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Schematic showing high-level multi-step process of neurogenesis and gliogenesis. Activation of proneural genes by EGF and FGF results in neural stem cell (NSC) differentiation. Upon Notch-Delta signaling between neighboring NSCs, a subset of cells will become neuronal progenitors (giving rise to
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Stem cell differentiation and Notch-Delta lateral inhibition in neural stem cells, resulting in the generation of neuronal and glia progenitors.
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neurons), whereas the inhibited cells will become glial progenitors (giving rise to astrocytes and oligodendrocytes).
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fibroblast growth factor receptor signaling pathway
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1051:Сигнальний шлях Notch
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971:03:25, 10 May 2019
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123:You can help
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22:File history
1008:Gliogenesis
616:copyrighted
266:share alike
260:attribution
145:Description
999:File usage
956:Dimensions
853:media type
723:9 May 2019
532:some value
168:9 May 2019
27:File usage
1083:59.05 dpc
1075:59.05 dpc
953:Thumbnail
950:Date/Time
868:image/png
742:data size
708:inception
429:astrocyte
344:stem cell
197:Licensing
154:English:
89:image/png
1059:Metadata
982:(384 KB)
887:checksum
757:393,560
304:Captions
249:to remix
243:to share
234:license.
178:Own work
37:Metadata
967:current
962:Comment
517:creator
328:depicts
308:English
137:Summary
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831:7,084
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395:neuron
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174:Source
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164:Date
17:File
572:URL
446:EGF
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