342:
319:
216:
241:
607:
600:
593:
348:
247:
29:
3512:
55:
2567:
Collins C, Duff C, Duncan AM, Planells-Cases R, Sun W, Norremolle A, et al. (July 1993). "Mapping of the human NMDA receptor subunit (NMDAR1) and the proposed NMDA receptor glutamate-binding subunit (NMDARA1) to chromosomes 9q34.3 and chromosome 8, respectively".
1668:
and is alternatively spliced, producing transcript variants differing in the C-terminus. The sequence of exon 5 is identical in vertebrates, with exon 5 splicing demonstrated in human, mouse and rat. Cell-specific factors are thought to control expression of different
2635:
Corasaniti MT, Melino G, Navarra M, Garaci E, Finazzi-Agrò A, Nisticò G (September 1995). "Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase".
2597:
Lannuzel A, Lledo PM, Lamghitnia HO, Vincent JD, Tardieu M (November 1995). "HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced i increase, alter i homeostasis and induce neurotoxicity in human embryonic neurons".
2117:
Adriani W, Felici A, Sargolini F, Roullet P, Usiello A, Oliverio A, Mele A (November 1998). "N-methyl-D-aspartate and dopamine receptor involvement in the modulation of locomotor activity and memory processes".
2381:
Magnuson DS, Knudsen BE, Geiger JD, Brownstone RM, Nath A (March 1995). "Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity".
2538:
Foldes RL, Rampersad V, Kamboj RK (September 1993). "Cloning and sequence analysis of cDNAs encoding human hippocampus N-methyl-D-aspartate receptor subunits: evidence for alternative RNA splicing".
2708:
Pittaluga A, Pattarini R, Severi P, Raiteri M (May 1996). "Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120".
3553:
2419:
Foldes RL, Rampersad V, Kamboj RK (September 1994). "Cloning and sequence analysis of additional splice variants encoding human N-methyl-D-aspartate receptor (hNR1) subunits".
2767:
355:
254:
1780:
Monyer H, Sprengel R, Schoepfer R, Herb A, Higuchi M, Lomeli H, et al. (May 1992). "Heteromeric NMDA receptors: molecular and functional distinction of subtypes".
2865:
2005:
Manta G, Spathis AD, Taraviras S, Kouvelas ED, Mitsacos A (August 2011). "Age and visual experience-dependent expression of NMDAR1 splice variants in rat retina".
2211:
Zimmer M, Fink TM, Franke Y, Lichter P, Spiess J (July 1995). "Cloning and structure of the gene encoding the human N-methyl-D-aspartate receptor (NMDAR1)".
2448:
Sheng M, Cummings J, Roldan LA, Jan YN, Jan LY (March 1994). "Changing subunit composition of heteromeric NMDA receptors during development of rat cortex".
2493:
Tingley WG, Roche KW, Thompson AK, Huganir RL (July 1993). "Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain".
1280:
1261:
177:
3546:
3577:
2760:
3587:
2330:"Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain"
1762:
1744:
3572:
3539:
2055:"Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1"
1568:
341:
2753:
2096:
Schröder HC, Perovic S, Kavsan V, Ushijima H, Müller WE (1998). "Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death".
3176:
3164:
1575:
318:
3196:
3073:
1834:
1731:
1710:
3209:
1645:
1727:
240:
215:
52:
1706:
157:
1899:"N-terminal alternative splicing of GluN1 regulates the maturation of excitatory synapses and seizure susceptibility"
354:
253:
1850:"Control of Long-Term Synaptic Potentiation and Learning by Alternative Splicing of the NMDA Receptor Subunit GluN1"
148:, GluN1, MRD8, NMDA1, NMDAR1, NR1, NMD-R1, glutamate ionotropic receptor NMDA type subunit 1, NDHMSR, NDHMSD, DEE101
3231:
3188:
347:
246:
3031:
2745:
3245:
2784:
1653:
1325:
165:
2242:"Molecular cloning and chromosomal localization of the key subunit of the human N-methyl-D-aspartate receptor"
1958:"Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data"
1306:
3519:
3432:
3582:
2780:
1652:
channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a
2502:
2457:
2341:
2288:
1910:
1789:
229:
144:
3445:
2155:
Dingledine R, Borges K, Bowie D, Traynelis SF (March 1999). "The glutamate receptor ion channels".
1657:
1551:
1547:
1543:
1533:
1529:
1521:
1517:
1494:
1490:
1460:
1456:
1452:
1442:
1438:
1430:
1426:
1403:
1399:
3248:
2983:
2792:
2733:
2696:
2623:
2526:
2481:
2407:
2143:
2030:
1879:
1813:
1649:
189:
1525:
1502:
1498:
1486:
1434:
1411:
1407:
1395:
714:
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
2725:
2688:
2653:
2615:
2585:
2555:
2518:
2473:
2436:
2399:
2369:
2316:
2263:
2228:
2199:
2164:
2135:
2105:
2084:
2022:
1987:
1938:
1871:
1805:
606:
599:
592:
137:
45:
3290:
3023:
2717:
2678:
2645:
2607:
2577:
2547:
2510:
2465:
2428:
2391:
2359:
2349:
2306:
2296:
2253:
2220:
2189:
2127:
2074:
2066:
2014:
1977:
1969:
1928:
1918:
1861:
1797:
434:
365:
309:
264:
185:
409:
2667:"Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit"
2277:"Inducible expression of neuronal glutamate receptor channels in the NT2 human cell line"
2506:
2461:
2345:
2292:
1914:
1793:
3523:
2857:
2809:
2611:
2275:
Younkin DP, Tang CM, Hardy M, Reddy UR, Shi QY, Pleasure SJ, et al. (March 1993).
2079:
2070:
2054:
1982:
1957:
1933:
1898:
2683:
2666:
2258:
2241:
1195:
1190:
1185:
1180:
1175:
1170:
1165:
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1155:
1150:
1145:
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1135:
1130:
1125:
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1115:
1110:
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1095:
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1065:
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1055:
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1045:
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1035:
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1025:
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1015:
1010:
1005:
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985:
980:
975:
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965:
960:
955:
950:
945:
940:
935:
930:
925:
920:
915:
910:
905:
900:
895:
890:
885:
880:
875:
859:
854:
849:
844:
839:
834:
829:
824:
819:
814:
809:
804:
799:
794:
789:
784:
779:
774:
769:
764:
759:
754:
749:
733:
728:
723:
718:
713:
708:
703:
698:
693:
688:
683:
678:
673:
668:
663:
658:
653:
648:
3566:
3335:
3265:
2849:
2801:
2721:
2649:
2551:
2432:
2364:
2329:
2311:
2276:
2224:
1883:
1682:
635:
2627:
2411:
2034:
3453:
2737:
2700:
2530:
2485:
2147:
1848:
Sengar AS, Li H, Zhang W, Leung C, Ramani AK, Saw NM, et al. (December 2019).
427:
206:
1817:
1801:
169:
2194:
2177:
1866:
1849:
193:
2776:
1767:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1749:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2334:
Proceedings of the
National Academy of Sciences of the United States of America
2281:
Proceedings of the
National Academy of Sciences of the United States of America
1973:
1903:
Proceedings of the
National Academy of Sciences of the United States of America
510:
2018:
326:
223:
173:
1664:, which is believed to underlie memory and learning. The gene consists of 21
2354:
1923:
1225:
570:
448:
393:
380:
292:
279:
181:
2581:
2301:
2203:
2168:
2026:
1991:
1942:
1875:
1835:"Entrez Gene: GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1"
2729:
2692:
2657:
2619:
2589:
2559:
2522:
2477:
2440:
2403:
2395:
2373:
2320:
2267:
2232:
2139:
2131:
2109:
2088:
2053:
Lin JW, Wyszynski M, Madhavan R, Sealock R, Kim JU, Sheng M (March 1998).
1809:
1615:
1610:
28:
1599:
1370:
1351:
3380:
3375:
3124:
1670:
1661:
1631:
1337:
1292:
3511:
114:
110:
106:
102:
98:
94:
90:
86:
82:
78:
74:
3370:
3365:
3360:
3355:
3350:
3345:
3144:
3139:
3134:
3129:
3119:
3114:
3109:
3104:
3099:
3094:
3089:
3084:
3008:
3000:
2992:
2953:
2945:
2937:
2929:
2921:
2913:
2905:
2897:
2889:
2881:
2873:
2514:
2469:
1673:, possibly contributing to the functional diversity of the subunits.
1583:
1247:
1897:
Liu H, Wang H, Peterson M, Zhang W, Hou G, Zhang ZW (October 2019).
1171:
positive regulation of reactive oxygen species biosynthetic process
3488:
3483:
3478:
3473:
3468:
3463:
3458:
3413:
3405:
3315:
3310:
3305:
3300:
3295:
3284:
3279:
3274:
3269:
3154:
3149:
3055:
3047:
3039:
2976:
2971:
2966:
2961:
2837:
2832:
2827:
2822:
2817:
2328:
Planells-Cases R, Sun W, Ferrer-Montiel AV, Montal M (June 1993).
1210:
1206:
3063:
1665:
1638:
161:
2749:
615:
2240:
Karp SJ, Masu M, Eki T, Ozawa K, Nakanishi S (February 1993).
1191:
positive regulation of cysteine-type endopeptidase activity
2665:
Ehlers MD, Zhang S, Bernhadt JP, Huganir RL (March 1996).
1644:
The protein encoded by this gene is a critical subunit of
2176:
King JE, Eugenin EA, Buckner CM, Berman JW (April 2006).
1956:
Herbrechter R, Hube N, Buchholz R, Reiner A (July 2021).
1146:
positive regulation of calcium ion transport into cytosol
1121:
positive regulation of transcription by RNA polymerase II
916:
positive regulation of excitatory postsynaptic potential
417:
3527:
582:
946:
regulation of long-term neuronal synaptic plasticity
679:
extracellularly glutamate-gated ion channel activity
3444:
3431:
3391:
3326:
3256:
3244:
3222:
3072:
3022:
2848:
2800:
2791:
1516:
1479:
1425:
1388:
860:
integral component of postsynaptic density membrane
541:
dentate gyrus of hippocampal formation granule cell
1723:
1721:
1719:
1702:
1700:
1698:
1036:respiratory gaseous exchange by respiratory system
364:
263:
981:ionotropic glutamate receptor signaling pathway
876:negative regulation of neuron apoptotic process
16:Protein-coding gene in the species Homo sapiens
1728:GRCm38: Ensembl release 89: ENSMUSG00000026959
3547:
2761:
1176:protein localization to postsynaptic membrane
1161:calcium ion transmembrane import into cytosol
8:
724:glutamate-gated calcium ion channel activity
1707:GRCh38: Ensembl release 89: ENSG00000176884
3554:
3540:
3441:
3253:
2797:
2768:
2754:
2746:
1513:
1422:
1221:
1001:regulation of neuronal synaptic plasticity
891:regulation of respiratory gaseous exchange
631:
405:
304:
201:
63:
2682:
2363:
2353:
2310:
2300:
2257:
2193:
2078:
1981:
1932:
1922:
1865:
1166:excitatory chemical synaptic transmission
1136:regulation of ion transmembrane transport
770:NMDA selective glutamate receptor complex
1829:
1827:
1656:. These subunits play a key role in the
1116:positive regulation of apoptotic process
1694:
1126:positive regulation of GTPase activity
956:regulation of neuron apoptotic process
704:ionotropic glutamate receptor activity
18:
815:integral component of plasma membrane
369:
330:
325:
268:
227:
222:
7:
3508:
3506:
2600:The European Journal of Neuroscience
1962:Cellular and Molecular Life Sciences
1196:regulation of NMDA receptor activity
1101:regulation of dendrite morphogenesis
886:synaptic transmission, glutamatergic
553:molecular layer of cerebellar cortex
2246:The Journal of Biological Chemistry
1131:calcium ion transmembrane transport
2612:10.1111/j.1460-9568.1995.tb00649.x
2071:10.1523/JNEUROSCI.18-06-02017.1998
1628:Glutamate receptor subunit zeta-1
1476:
1385:
1361:
1342:
1316:
1297:
1271:
1252:
734:protein-containing complex binding
587:
505:
443:
422:
14:
1634:that in humans is encoded by the
1181:cellular response to amyloid-beta
1091:ephrin receptor signaling pathway
1041:regulation of synaptic plasticity
986:excitatory postsynaptic potential
3510:
2722:10.1097/00002030-199605000-00003
1081:regulation of cell communication
1026:cellular calcium ion homeostasis
901:regulation of membrane potential
694:NMDA glutamate receptor activity
605:
598:
591:
353:
346:
340:
317:
252:
245:
239:
214:
27:
3578:Ionotropic glutamate receptors
1646:N-methyl-D-aspartate receptors
1031:cation transmembrane transport
906:regulation of synapse assembly
800:integral component of membrane
616:More reference expression data
571:More reference expression data
459:right hemisphere of cerebellum
1:
2684:10.1016/S0092-8674(00)81052-1
2259:10.1016/S0021-9258(18)53754-6
1802:10.1126/science.256.5060.1217
1156:protein heterotetramerization
845:postsynaptic density membrane
338:
237:
3588:Transmembrane receptor stubs
3526:. You can help Knowledge by
2650:10.1016/1055-8330(95)90021-7
2552:10.1016/0378-1119(93)90309-Q
2433:10.1016/0378-1119(94)90089-2
2225:10.1016/0378-1119(95)00044-7
2195:10.1016/j.micinf.2005.11.014
1867:10.1016/j.celrep.2019.11.087
3573:Genes on human chromosome 9
2178:"HIV tat and neurotoxicity"
2120:Experimental Brain Research
2059:The Journal of Neuroscience
1106:ion transmembrane transport
1061:cerebral cortex development
1051:propylene metabolic process
729:signaling receptor activity
3604:
3505:
1974:10.1007/s00018-021-03865-z
1151:calcium-mediated signaling
1071:sensory perception of pain
1056:conditioned taste aversion
971:regulation of axonogenesis
654:signaling receptor binding
3328:Voltage- and ligand-gated
2785:ligand-gated ion channels
2019:10.1007/s11064-011-0467-5
1763:"Mouse PubMed Reference:"
1745:"Human PubMed Reference:"
1614:
1609:
1605:
1598:
1582:
1569:Chr 9: 137.14 – 137.17 Mb
1563:
1540:
1483:
1472:
1449:
1392:
1381:
1368:
1364:
1349:
1345:
1336:
1323:
1319:
1304:
1300:
1291:
1278:
1274:
1259:
1255:
1246:
1231:
1224:
1220:
1204:
951:adult locomotory behavior
634:
630:
613:
590:
581:
568:
517:
508:
467:anterior cingulate cortex
455:
446:
416:
408:
404:
387:
374:
337:
316:
307:
303:
286:
273:
236:
213:
204:
200:
155:
152:
142:
135:
130:
71:
66:
49:
44:
39:
35:
26:
21:
1654:ligand-gated ion channel
709:neurotransmitter binding
689:calcium channel activity
3074:Nicotinic acetylcholine
2355:10.1073/pnas.90.11.5057
2157:Pharmacological Reviews
1924:10.1073/pnas.1905721116
1576:Chr 2: 25.18 – 25.21 Mb
1016:calcium ion homeostasis
896:response to amphetamine
674:cation channel activity
3522:-related article is a
3520:transmembrane receptor
2582:10.1006/geno.1993.1311
2302:10.1073/pnas.90.6.2174
2182:Microbes and Infection
2007:Neurochemical Research
533:superior frontal gyrus
2781:cell surface receptor
2396:10.1002/ana.410370314
2132:10.1007/s002210050544
976:neuromuscular process
926:calcium ion transport
855:glutamatergic synapse
795:endoplasmic reticulum
755:postsynaptic membrane
529:primary visual cortex
3446:Purinergic receptors
1860:(13): 4285–4294.e5.
1046:response to morphine
1006:associative learning
941:male mating behavior
810:postsynaptic density
719:amyloid-beta binding
699:ion channel activity
557:primary motor cortex
371:2 A3|2 17.14 cM
332:Chromosome 2 (mouse)
230:Chromosome 9 (human)
67:List of PDB id codes
40:Available structures
2507:1993Natur.364...70T
2462:1994Natur.368..144S
2384:Annals of Neurology
2346:1993PNAS...90.5057P
2293:1993PNAS...90.2174Y
1915:2019PNAS..11621207L
1909:(42): 21207–21212.
1794:1992Sci...256.1217M
1788:(5060): 1217–1221.
1186:response to glycine
936:prepulse inhibition
921:response to ethanol
649:calcium ion binding
549:superior colliculus
3214:β1δε - Muscle type
2793:Cys-loop receptors
1650:glutamate receptor
1326:ENSMUSG00000026959
1076:olfactory learning
991:learning or memory
869:Biological process
820:excitatory synapse
743:Cellular component
664:calmodulin binding
642:Molecular function
463:right frontal lobe
3535:
3534:
3503:
3502:
3499:
3498:
3427:
3426:
3258:Ligand-gated only
3240:
3239:
2638:Neurodegeneration
2606:(11): 2285–2293.
2456:(6467): 144–147.
2340:(11): 5057–5061.
1968:(14): 5605–5630.
1648:, members of the
1625:
1624:
1621:
1620:
1594:
1593:
1559:
1558:
1510:
1509:
1468:
1467:
1419:
1418:
1377:
1376:
1358:
1357:
1332:
1331:
1313:
1312:
1287:
1286:
1268:
1267:
1216:
1215:
1141:brain development
931:suckling behavior
850:synaptic membrane
775:neuron projection
684:glutamate binding
626:
625:
622:
621:
577:
576:
564:
563:
545:cerebellar cortex
525:entorhinal cortex
521:perirhinal cortex
502:
501:
475:prefrontal cortex
471:nucleus accumbens
400:
399:
299:
298:
194:GRIN1 - orthologs
126:
125:
122:
121:
50:Ortholog search:
3595:
3556:
3549:
3542:
3514:
3507:
3442:
3254:
2798:
2770:
2763:
2756:
2747:
2741:
2704:
2686:
2661:
2631:
2593:
2563:
2534:
2515:10.1038/364070a0
2489:
2470:10.1038/368144a0
2444:
2415:
2377:
2367:
2357:
2324:
2314:
2304:
2287:(6): 2174–2178.
2271:
2261:
2252:(5): 3728–3733.
2236:
2207:
2197:
2188:(5): 1347–1357.
2172:
2151:
2113:
2104:(4–5): 683–688.
2092:
2082:
2065:(6): 2017–2027.
2039:
2038:
2013:(8): 1417–1425.
2002:
1996:
1995:
1985:
1953:
1947:
1946:
1936:
1926:
1894:
1888:
1887:
1869:
1845:
1839:
1838:
1831:
1822:
1821:
1777:
1771:
1770:
1759:
1753:
1752:
1741:
1735:
1725:
1714:
1704:
1607:
1606:
1578:
1571:
1554:
1514:
1505:
1477:
1473:RefSeq (protein)
1463:
1423:
1414:
1386:
1362:
1343:
1317:
1298:
1272:
1253:
1222:
1111:long-term memory
1021:cation transport
1011:startle response
780:synaptic vesicle
632:
618:
609:
602:
595:
588:
573:
513:
511:Top expressed in
506:
495:Brodmann area 10
451:
449:Top expressed in
444:
423:
406:
396:
383:
372:
357:
350:
344:
333:
321:
305:
295:
282:
271:
256:
249:
243:
232:
218:
202:
196:
147:
140:
117:
64:
58:
37:
36:
31:
19:
3603:
3602:
3598:
3597:
3596:
3594:
3593:
3592:
3563:
3562:
3561:
3560:
3504:
3495:
3423:
3417:
3409:
3387:
3322:
3236:
3218:
3213:
3205:- Ganglion type
3204:
3200:
3192:
3184:
3180:
3172:
3168:
3068:
3059:
3051:
3043:
3035:
3018:
3012:
3004:
2996:
2987:
2957:
2949:
2941:
2933:
2925:
2917:
2909:
2901:
2893:
2885:
2877:
2869:
2861:
2844:
2813:
2787:
2774:
2744:
2707:
2664:
2634:
2596:
2566:
2537:
2501:(6432): 70–73.
2492:
2447:
2418:
2380:
2327:
2274:
2239:
2210:
2175:
2154:
2116:
2098:Neurotoxicology
2095:
2052:
2048:
2046:Further reading
2043:
2042:
2004:
2003:
1999:
1955:
1954:
1950:
1896:
1895:
1891:
1847:
1846:
1842:
1833:
1832:
1825:
1779:
1778:
1774:
1761:
1760:
1756:
1743:
1742:
1738:
1726:
1717:
1705:
1696:
1691:
1679:
1616:View/Edit Mouse
1611:View/Edit Human
1574:
1567:
1564:Location (UCSC)
1550:
1546:
1542:
1536:
1532:
1528:
1524:
1520:
1501:
1497:
1493:
1489:
1485:
1459:
1455:
1451:
1445:
1441:
1437:
1433:
1429:
1410:
1406:
1402:
1398:
1394:
1307:ENSG00000176884
1200:
1086:visual learning
996:social behavior
881:pons maturation
864:
840:terminal bouton
805:plasma membrane
785:dendritic spine
738:
669:protein binding
659:glycine binding
614:
604:
603:
597:
596:
569:
560:
555:
551:
547:
543:
539:
535:
531:
527:
523:
509:
498:
493:
491:caudate nucleus
489:
485:
481:
479:Brodmann area 9
477:
473:
469:
465:
461:
447:
391:
378:
370:
360:
359:
358:
351:
331:
308:Gene location (
290:
277:
269:
259:
258:
257:
250:
228:
205:Gene location (
156:
143:
136:
73:
51:
17:
12:
11:
5:
3601:
3599:
3591:
3590:
3585:
3580:
3575:
3565:
3564:
3559:
3558:
3551:
3544:
3536:
3533:
3532:
3515:
3501:
3500:
3497:
3496:
3494:
3493:
3492:
3491:
3486:
3481:
3476:
3471:
3466:
3461:
3450:
3448:
3439:
3437:gated channels
3429:
3428:
3425:
3424:
3422:
3421:
3420:
3419:
3415:
3411:
3407:
3397:
3395:
3389:
3388:
3386:
3385:
3384:
3383:
3378:
3373:
3368:
3363:
3358:
3353:
3348:
3343:
3332:
3330:
3324:
3323:
3321:
3320:
3319:
3318:
3313:
3308:
3303:
3298:
3288:
3282:
3277:
3272:
3262:
3260:
3251:
3242:
3241:
3238:
3237:
3235:
3234:
3232:Zinc-activated
3228:
3226:
3220:
3219:
3217:
3216:
3211:
3207:
3202:
3198:
3194:
3190:
3186:
3182:
3178:
3174:
3170:
3166:
3158:
3157:
3152:
3147:
3142:
3137:
3132:
3127:
3122:
3117:
3112:
3107:
3102:
3097:
3092:
3087:
3078:
3076:
3070:
3069:
3067:
3066:
3061:
3057:
3053:
3049:
3045:
3041:
3037:
3033:
3028:
3026:
3020:
3019:
3017:
3016:
3015:
3014:
3010:
3006:
3002:
2998:
2994:
2985:
2981:
2980:
2979:
2974:
2969:
2964:
2959:
2955:
2951:
2947:
2943:
2939:
2935:
2931:
2927:
2923:
2919:
2915:
2911:
2907:
2903:
2899:
2895:
2891:
2887:
2883:
2879:
2875:
2871:
2867:
2859:
2854:
2852:
2846:
2845:
2843:
2842:
2841:
2840:
2835:
2830:
2825:
2820:
2811:
2806:
2804:
2802:5-HT/serotonin
2795:
2789:
2788:
2775:
2773:
2772:
2765:
2758:
2750:
2743:
2742:
2716:(5): 463–468.
2705:
2677:(5): 745–755.
2662:
2644:(3): 315–321.
2632:
2594:
2576:(1): 237–239.
2564:
2546:(2): 293–298.
2535:
2490:
2445:
2427:(2): 303–304.
2416:
2390:(3): 373–380.
2378:
2325:
2272:
2237:
2219:(2): 219–223.
2208:
2173:
2152:
2126:(1–2): 52–59.
2114:
2093:
2049:
2047:
2044:
2041:
2040:
1997:
1948:
1889:
1840:
1823:
1772:
1754:
1736:
1715:
1693:
1692:
1690:
1687:
1686:
1685:
1678:
1675:
1623:
1622:
1619:
1618:
1613:
1603:
1602:
1596:
1595:
1592:
1591:
1589:
1587:
1580:
1579:
1572:
1565:
1561:
1560:
1557:
1556:
1538:
1537:
1511:
1508:
1507:
1481:
1480:
1474:
1470:
1469:
1466:
1465:
1447:
1446:
1420:
1417:
1416:
1390:
1389:
1383:
1379:
1378:
1375:
1374:
1366:
1365:
1359:
1356:
1355:
1347:
1346:
1340:
1334:
1333:
1330:
1329:
1321:
1320:
1314:
1311:
1310:
1302:
1301:
1295:
1289:
1288:
1285:
1284:
1276:
1275:
1269:
1266:
1265:
1257:
1256:
1250:
1244:
1243:
1238:
1233:
1229:
1228:
1218:
1217:
1214:
1213:
1202:
1201:
1199:
1198:
1193:
1188:
1183:
1178:
1173:
1168:
1163:
1158:
1153:
1148:
1143:
1138:
1133:
1128:
1123:
1118:
1113:
1108:
1103:
1098:
1093:
1088:
1083:
1078:
1073:
1068:
1063:
1058:
1053:
1048:
1043:
1038:
1033:
1028:
1023:
1018:
1013:
1008:
1003:
998:
993:
988:
983:
978:
973:
968:
963:
958:
953:
948:
943:
938:
933:
928:
923:
918:
913:
908:
903:
898:
893:
888:
883:
878:
872:
870:
866:
865:
863:
862:
857:
852:
847:
842:
837:
835:synaptic cleft
832:
827:
822:
817:
812:
807:
802:
797:
792:
787:
782:
777:
772:
767:
762:
757:
752:
746:
744:
740:
739:
737:
736:
731:
726:
721:
716:
711:
706:
701:
696:
691:
686:
681:
676:
671:
666:
661:
656:
651:
645:
643:
639:
638:
628:
627:
624:
623:
620:
619:
611:
610:
585:
579:
578:
575:
574:
566:
565:
562:
561:
559:
558:
554:
550:
546:
542:
538:
534:
530:
526:
522:
518:
515:
514:
503:
500:
499:
497:
496:
492:
488:
484:
480:
476:
472:
468:
464:
460:
456:
453:
452:
440:
439:
431:
420:
414:
413:
410:RNA expression
402:
401:
398:
397:
389:
385:
384:
376:
373:
368:
362:
361:
352:
345:
339:
335:
334:
329:
323:
322:
314:
313:
301:
300:
297:
296:
288:
284:
283:
275:
272:
267:
261:
260:
251:
244:
238:
234:
233:
226:
220:
219:
211:
210:
198:
197:
154:
150:
149:
141:
133:
132:
128:
127:
124:
123:
120:
119:
69:
68:
60:
59:
48:
42:
41:
33:
32:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
3600:
3589:
3586:
3584:
3581:
3579:
3576:
3574:
3571:
3570:
3568:
3557:
3552:
3550:
3545:
3543:
3538:
3537:
3531:
3529:
3525:
3521:
3516:
3513:
3509:
3490:
3487:
3485:
3482:
3480:
3477:
3475:
3472:
3470:
3467:
3465:
3462:
3460:
3457:
3456:
3455:
3452:
3451:
3449:
3447:
3443:
3440:
3438:
3434:
3430:
3418:
3412:
3410:
3404:
3403:
3402:
3399:
3398:
3396:
3394:
3390:
3382:
3379:
3377:
3374:
3372:
3369:
3367:
3364:
3362:
3359:
3357:
3354:
3352:
3349:
3347:
3344:
3342:
3339:
3338:
3337:
3334:
3333:
3331:
3329:
3325:
3317:
3314:
3312:
3309:
3307:
3304:
3302:
3299:
3297:
3294:
3293:
3292:
3289:
3286:
3283:
3281:
3278:
3276:
3273:
3271:
3267:
3264:
3263:
3261:
3259:
3255:
3252:
3250:
3247:
3243:
3233:
3230:
3229:
3227:
3225:
3221:
3215:
3208:
3206:
3195:
3193:
3187:
3185:
3175:
3173:
3163:
3160:
3159:
3156:
3153:
3151:
3148:
3146:
3143:
3141:
3138:
3136:
3133:
3131:
3128:
3126:
3123:
3121:
3118:
3116:
3113:
3111:
3108:
3106:
3103:
3101:
3098:
3096:
3093:
3091:
3088:
3086:
3083:
3080:
3079:
3077:
3075:
3071:
3065:
3062:
3060:
3054:
3052:
3046:
3044:
3038:
3036:
3030:
3029:
3027:
3025:
3021:
3013:
3007:
3005:
2999:
2997:
2991:
2990:
2989:
2982:
2978:
2975:
2973:
2970:
2968:
2965:
2963:
2960:
2958:
2952:
2950:
2944:
2942:
2936:
2934:
2928:
2926:
2920:
2918:
2912:
2910:
2904:
2902:
2896:
2894:
2888:
2886:
2880:
2878:
2872:
2870:
2864:
2863:
2862:
2856:
2855:
2853:
2851:
2847:
2839:
2836:
2834:
2831:
2829:
2826:
2824:
2821:
2819:
2816:
2815:
2814:
2808:
2807:
2805:
2803:
2799:
2796:
2794:
2790:
2786:
2782:
2778:
2771:
2766:
2764:
2759:
2757:
2752:
2751:
2748:
2739:
2735:
2731:
2727:
2723:
2719:
2715:
2711:
2706:
2702:
2698:
2694:
2690:
2685:
2680:
2676:
2672:
2668:
2663:
2659:
2655:
2651:
2647:
2643:
2639:
2633:
2629:
2625:
2621:
2617:
2613:
2609:
2605:
2601:
2595:
2591:
2587:
2583:
2579:
2575:
2571:
2565:
2561:
2557:
2553:
2549:
2545:
2541:
2536:
2532:
2528:
2524:
2520:
2516:
2512:
2508:
2504:
2500:
2496:
2491:
2487:
2483:
2479:
2475:
2471:
2467:
2463:
2459:
2455:
2451:
2446:
2442:
2438:
2434:
2430:
2426:
2422:
2417:
2413:
2409:
2405:
2401:
2397:
2393:
2389:
2385:
2379:
2375:
2371:
2366:
2361:
2356:
2351:
2347:
2343:
2339:
2335:
2331:
2326:
2322:
2318:
2313:
2308:
2303:
2298:
2294:
2290:
2286:
2282:
2278:
2273:
2269:
2265:
2260:
2255:
2251:
2247:
2243:
2238:
2234:
2230:
2226:
2222:
2218:
2214:
2209:
2205:
2201:
2196:
2191:
2187:
2183:
2179:
2174:
2170:
2166:
2162:
2158:
2153:
2149:
2145:
2141:
2137:
2133:
2129:
2125:
2121:
2115:
2111:
2107:
2103:
2099:
2094:
2090:
2086:
2081:
2076:
2072:
2068:
2064:
2060:
2056:
2051:
2050:
2045:
2036:
2032:
2028:
2024:
2020:
2016:
2012:
2008:
2001:
1998:
1993:
1989:
1984:
1979:
1975:
1971:
1967:
1963:
1959:
1952:
1949:
1944:
1940:
1935:
1930:
1925:
1920:
1916:
1912:
1908:
1904:
1900:
1893:
1890:
1885:
1881:
1877:
1873:
1868:
1863:
1859:
1855:
1851:
1844:
1841:
1836:
1830:
1828:
1824:
1819:
1815:
1811:
1807:
1803:
1799:
1795:
1791:
1787:
1783:
1776:
1773:
1768:
1764:
1758:
1755:
1750:
1746:
1740:
1737:
1733:
1729:
1724:
1722:
1720:
1716:
1712:
1708:
1703:
1701:
1699:
1695:
1688:
1684:
1683:NMDA receptor
1681:
1680:
1676:
1674:
1672:
1667:
1663:
1659:
1655:
1651:
1647:
1642:
1640:
1637:
1633:
1629:
1617:
1612:
1608:
1604:
1601:
1597:
1590:
1588:
1585:
1581:
1577:
1573:
1570:
1566:
1562:
1555:
1553:
1549:
1545:
1539:
1535:
1531:
1527:
1523:
1519:
1515:
1512:
1506:
1504:
1500:
1496:
1492:
1488:
1482:
1478:
1475:
1471:
1464:
1462:
1458:
1454:
1448:
1444:
1440:
1436:
1432:
1428:
1424:
1421:
1415:
1413:
1409:
1405:
1401:
1397:
1391:
1387:
1384:
1382:RefSeq (mRNA)
1380:
1373:
1372:
1367:
1363:
1360:
1354:
1353:
1348:
1344:
1341:
1339:
1335:
1328:
1327:
1322:
1318:
1315:
1309:
1308:
1303:
1299:
1296:
1294:
1290:
1283:
1282:
1277:
1273:
1270:
1264:
1263:
1258:
1254:
1251:
1249:
1245:
1242:
1239:
1237:
1234:
1230:
1227:
1223:
1219:
1212:
1208:
1203:
1197:
1194:
1192:
1189:
1187:
1184:
1182:
1179:
1177:
1174:
1172:
1169:
1167:
1164:
1162:
1159:
1157:
1154:
1152:
1149:
1147:
1144:
1142:
1139:
1137:
1134:
1132:
1129:
1127:
1124:
1122:
1119:
1117:
1114:
1112:
1109:
1107:
1104:
1102:
1099:
1097:
1094:
1092:
1089:
1087:
1084:
1082:
1079:
1077:
1074:
1072:
1069:
1067:
1064:
1062:
1059:
1057:
1054:
1052:
1049:
1047:
1044:
1042:
1039:
1037:
1034:
1032:
1029:
1027:
1024:
1022:
1019:
1017:
1014:
1012:
1009:
1007:
1004:
1002:
999:
997:
994:
992:
989:
987:
984:
982:
979:
977:
974:
972:
969:
967:
964:
962:
961:ion transport
959:
957:
954:
952:
949:
947:
944:
942:
939:
937:
934:
932:
929:
927:
924:
922:
919:
917:
914:
912:
909:
907:
904:
902:
899:
897:
894:
892:
889:
887:
884:
882:
879:
877:
874:
873:
871:
868:
867:
861:
858:
856:
853:
851:
848:
846:
843:
841:
838:
836:
833:
831:
828:
826:
825:cell junction
823:
821:
818:
816:
813:
811:
808:
806:
803:
801:
798:
796:
793:
791:
788:
786:
783:
781:
778:
776:
773:
771:
768:
766:
763:
761:
758:
756:
753:
751:
748:
747:
745:
742:
741:
735:
732:
730:
727:
725:
722:
720:
717:
715:
712:
710:
707:
705:
702:
700:
697:
695:
692:
690:
687:
685:
682:
680:
677:
675:
672:
670:
667:
665:
662:
660:
657:
655:
652:
650:
647:
646:
644:
641:
640:
637:
636:Gene ontology
633:
629:
617:
612:
608:
601:
594:
589:
586:
584:
580:
572:
567:
556:
552:
548:
544:
540:
536:
532:
528:
524:
520:
519:
516:
512:
507:
504:
494:
490:
486:
482:
478:
474:
470:
466:
462:
458:
457:
454:
450:
445:
442:
441:
438:
436:
432:
430:
429:
425:
424:
421:
419:
415:
411:
407:
403:
395:
390:
386:
382:
377:
367:
363:
356:
349:
343:
336:
328:
324:
320:
315:
311:
306:
302:
294:
289:
285:
281:
276:
266:
262:
255:
248:
242:
235:
231:
225:
221:
217:
212:
208:
203:
199:
195:
191:
187:
183:
179:
175:
171:
167:
163:
159:
151:
146:
139:
134:
129:
118:
116:
112:
108:
104:
100:
96:
92:
88:
84:
80:
76:
70:
65:
62:
61:
57:
54:
47:
43:
38:
34:
30:
25:
20:
3583:Ion channels
3528:expanding it
3517:
3436:
3400:
3392:
3340:
3327:
3257:
3223:
3161:
3081:
2713:
2709:
2674:
2670:
2641:
2637:
2603:
2599:
2573:
2569:
2543:
2539:
2498:
2494:
2453:
2449:
2424:
2420:
2387:
2383:
2337:
2333:
2284:
2280:
2249:
2245:
2216:
2212:
2185:
2181:
2160:
2156:
2123:
2119:
2101:
2097:
2062:
2058:
2010:
2006:
2000:
1965:
1961:
1951:
1906:
1902:
1892:
1857:
1854:Cell Reports
1853:
1843:
1785:
1781:
1775:
1766:
1757:
1748:
1739:
1643:
1635:
1627:
1626:
1552:NP_001359491
1548:NP_001359490
1544:NP_001359489
1541:
1534:NP_001359488
1530:NP_001359487
1522:NP_001171128
1518:NP_001171127
1495:NP_001172020
1491:NP_001172019
1484:
1461:NM_001372562
1457:NM_001372561
1453:NM_001372560
1450:
1443:NM_001372559
1439:NM_001372558
1431:NM_001177657
1427:NM_001177656
1404:NM_001185091
1400:NM_001185090
1393:
1369:
1350:
1324:
1305:
1279:
1260:
1240:
1235:
1096:MAPK cascade
790:cell surface
433:
426:
291:137,168,756
278:137,139,154
153:External IDs
72:
2777:Ion channel
2163:(1): 7–61.
392:25,209,199
379:25,181,193
131:Identifiers
3567:Categories
3249:glutamates
3246:Ionotropic
3162:pentamers:
1734:, May 2017
1713:, May 2017
1689:References
1658:plasticity
437:(ortholog)
174:HomoloGene
3082:monomers:
1884:209482250
1526:NP_032195
1503:NP_067544
1499:NP_015566
1487:NP_000823
1435:NM_008169
1412:NM_021569
1408:NM_007327
1396:NM_000832
1226:Orthologs
1066:transport
750:cytoplasm
537:CA3 field
182:GeneCards
3393:‘Orphan’
2628:27201873
2570:Genomics
2412:24405132
2204:16697675
2169:10049997
2035:11853676
2027:21499738
1992:34100982
1943:31570583
1876:31875540
1730:–
1709:–
1677:See also
1671:isoforms
1662:synapses
1600:Wikidata
1205:Sources:
911:learning
830:dendrite
760:membrane
487:amygdala
3291:Kainate
3024:Glycine
2738:1669986
2730:8724036
2701:1376853
2693:8625412
2658:8581564
2620:8563977
2590:8406459
2560:8406025
2531:4322831
2523:8316301
2503:Bibcode
2486:4332025
2478:8139656
2458:Bibcode
2441:7926821
2404:7695237
2374:7685113
2342:Bibcode
2321:7681588
2289:Bibcode
2268:7679115
2233:7622053
2148:8388670
2140:9835392
2110:9745929
2089:9482789
2080:6792910
1983:8257547
1934:6800312
1911:Bibcode
1810:1350383
1790:Bibcode
1782:Science
1732:Ensembl
1711:Ensembl
1632:protein
1338:UniProt
1293:Ensembl
1232:Species
1211:QuickGO
765:synapse
483:putamen
412:pattern
138:Aliases
2736:
2728:
2699:
2691:
2656:
2626:
2618:
2588:
2558:
2529:
2521:
2495:Nature
2484:
2476:
2450:Nature
2439:
2410:
2402:
2372:
2362:
2319:
2309:
2266:
2231:
2202:
2167:
2146:
2138:
2108:
2087:
2077:
2033:
2025:
1990:
1980:
1941:
1931:
1882:
1874:
1818:989677
1816:
1808:
1586:search
1584:PubMed
1371:P35438
1352:Q05586
1248:Entrez
966:memory
583:BioGPS
270:9q34.3
162:138249
3518:This
2734:S2CID
2697:S2CID
2624:S2CID
2527:S2CID
2482:S2CID
2408:S2CID
2365:46653
2312:46048
2144:S2CID
2031:S2CID
1880:S2CID
1814:S2CID
1666:exons
1636:GRIN1
1630:is a
1281:14810
1241:Mouse
1236:Human
1207:Amigo
435:Mouse
428:Human
375:Start
310:Mouse
274:Start
207:Human
186:GRIN1
170:95819
145:GRIN1
22:GRIN1
3524:stub
3401:GluD
3336:NMDA
3266:AMPA
3224:Zinc
3210:(α1)
3201:(β4)
3197:(α1)
3189:(α7)
3181:(β2)
3177:(α4)
3169:(β4)
3165:(α3)
2984:GABA
2858:GABA
2850:GABA
2810:5-HT
2726:PMID
2710:AIDS
2689:PMID
2671:Cell
2654:PMID
2616:PMID
2586:PMID
2556:PMID
2540:Gene
2519:PMID
2474:PMID
2437:PMID
2421:Gene
2400:PMID
2370:PMID
2317:PMID
2264:PMID
2229:PMID
2213:Gene
2200:PMID
2165:PMID
2136:PMID
2106:PMID
2085:PMID
2023:PMID
1988:PMID
1939:PMID
1872:PMID
1806:PMID
1639:gene
1262:2902
418:Bgee
366:Band
327:Chr.
265:Band
224:Chr.
178:7187
158:OMIM
115:5KDT
111:5KCJ
107:5I2K
103:5I2N
99:5H8F
95:5H8Q
91:5H8H
87:5H8N
83:3BYA
79:2NR1
75:2HQW
56:RCSB
53:PDBe
3454:P2X
3433:ATP
3381:L1B
3376:L1A
3125:α10
2718:doi
2679:doi
2646:doi
2608:doi
2578:doi
2548:doi
2544:131
2511:doi
2499:364
2466:doi
2454:368
2429:doi
2425:147
2392:doi
2360:PMC
2350:doi
2307:PMC
2297:doi
2254:doi
2250:268
2221:doi
2217:159
2190:doi
2128:doi
2124:123
2075:PMC
2067:doi
2015:doi
1978:PMC
1970:doi
1929:PMC
1919:doi
1907:116
1862:doi
1798:doi
1786:256
1660:of
388:End
287:End
190:OMA
166:MGI
46:PDB
3569::
3371:3B
3366:3A
3361:2D
3356:2C
3351:2B
3346:2A
3145:β4
3140:β3
3135:β2
3130:β1
3120:α9
3115:α7
3110:α6
3105:α5
3100:α4
3095:α3
3090:α2
3085:α1
2988:-ρ
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