Knowledge

GRIN2C

Source 📝

242: 219: 116: 141: 2826: 493: 248: 147: 1279:
Kalsi G, Whiting P, Bourdelles BL, Callen D, Barnard EA, Gurling H (Apr 1998). "Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation
1130:
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA
1624:
Corasaniti MT, Melino G, Navarra M, Garaci E, Finazzi-Agrò A, Nisticò G (1995). "Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase".
1586:
Lannuzel A, Lledo PM, Lamghitnia HO, Vincent JD, Tardieu M (1995). "HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced i increase, alter i homeostasis and induce neurotoxicity in human embryonic neurons".
1556:
Takano H, Onodera O, Tanaka H, Mori H, Sakimura K, Hori T, Kobayashi H, Mishina M, Tsuji S (1993). "Chromosomal localization of the epsilon 1, epsilon 3 and zeta 1 subunit genes of the human NMDA receptor channel".
1519:
Magnuson DS, Knudsen BE, Geiger JD, Brownstone RM, Nath A (1995). "Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity".
1437:
Monyer H, Sprengel R, Schoepfer R, Herb A, Higuchi M, Lomeli H, Burnashev N, Sakmann B, Seeburg PH (1992). "Heteromeric NMDA receptors: molecular and functional distinction of subtypes".
1654:
Pittaluga A, Pattarini R, Severi P, Raiteri M (1996). "Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120".
1765:
Toggas SM, Masliah E, Mucke L (1996). "Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine".
1874:
Lin YJ, Bovetto S, Carver JM, Giordano T (1996). "Cloning of the cDNA for the human NMDA receptor NR2C subunit and its expression in the central nervous system and periphery".
2078: 1841:"Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase" 255: 154: 2176: 2867: 1907:(1998). "CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins". 1946:"HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism" 2046: 1482:
Kornau HC, Schenker LT, Kennedy MB, Seeburg PH (1995). "Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95".
841: 822: 77: 1802:
Dreyer EB, Lipton SA (1995). "The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid".
2896: 2071: 2886: 1261: 1243: 241: 2860: 1056: 2064: 1381:
Schröder HC, Perovic S, Kavsan V, Ushijima H, Müller WE (1998). "Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death".
1049: 218: 2487: 2475: 2507: 2384: 1691:
Wu P, Price P, Du B, Hatch WC, Terwilliger EF (1996). "Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons".
1318: 2891: 1230: 1209: 1985:"The human N-methyl-D-aspartate receptor 2C subunit: genomic analysis, distribution in human brain, and functional expression" 2853: 2520: 140: 115: 1226: 1205: 57: 1156: 254: 153: 1728:
Bennett BA, Rusyniak DE, Hollingsworth CK (1995). "HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures".
2542: 2499: 247: 146: 2342: 2056: 2556: 2095: 2037: 886: 65: 1337:"Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102" 867: 2743: 1980: 2091: 129: 1491: 1446: 44: 2756: 2033: 1011: 960: 2559: 2294: 2103: 2014: 1932: 1827: 1790: 1753: 1716: 1679: 1612: 1544: 1470: 1176: 89: 1032: 1007: 981: 956: 575:
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
2006: 1967: 1924: 1904: 1891: 1862: 1819: 1782: 1745: 1708: 1671: 1642: 1604: 1574: 1536: 1507: 1462: 1425: 1390: 1358: 1297: 37: 2833: 2825: 2601: 2334: 1996: 1957: 1916: 1883: 1852: 1811: 1774: 1737: 1700: 1663: 1634: 1596: 1566: 1528: 1499: 1454: 1415: 1348: 1289: 492: 334: 265: 209: 164: 85: 309: 1979:
Daggett LP, Johnson EC, Varney MA, Lin FF, Hess SD, Deal CR, Jachec C, Lu CC, Kerner JA,
2001: 1984: 1495: 1450: 2837: 2168: 2120: 1815: 1600: 1887: 756: 751: 746: 741: 736: 731: 726: 721: 716: 711: 706: 701: 696: 691: 686: 681: 676: 671: 666: 661: 645: 640: 635: 630: 625: 620: 615: 610: 605: 600: 595: 590: 574: 569: 564: 559: 554: 549: 544: 539: 534: 2880: 2646: 2576: 2160: 2112: 2050: 1778: 1741: 1704: 1667: 1638: 1181: 521: 2018: 1936: 1794: 1757: 1720: 1616: 1548: 2764: 1831: 1683: 327: 106: 1474: 1458: 69: 1420: 1403: 93: 2087: 1266:
National Center for Biotechnology Information, U.S. National Library of Medicine
1248:
National Center for Biotechnology Information, U.S. National Library of Medicine
410: 1131:
receptor channels are heteromers composed of the key receptor subunit NMDAR1 (
226: 123: 73: 1962: 1945: 1319:"Entrez Gene: GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C" 1503: 786: 470: 348: 293: 280: 192: 179: 81: 1920: 1857: 1840: 1570: 1429: 1362: 1353: 1336: 1293: 48:, GluN2C, NMDAR2C, NR2C, glutamate ionotropic receptor NMDA type subunit 2C 2010: 1971: 1928: 1895: 1866: 1823: 1786: 1749: 1712: 1675: 1646: 1608: 1578: 1540: 1532: 1511: 1466: 1394: 1301: 1096: 1091: 1080: 931: 912: 2691: 2686: 2435: 1112: 898: 853: 2681: 2676: 2671: 2661: 2656: 2455: 2450: 2445: 2440: 2430: 2425: 2420: 2415: 2410: 2405: 2400: 2395: 2319: 2311: 2303: 2264: 2256: 2248: 2240: 2232: 2224: 2216: 2208: 2200: 2192: 2184: 1144: 1140: 1136: 1064: 808: 2799: 2794: 2789: 2784: 2779: 2774: 2769: 2724: 2716: 2651: 2626: 2621: 2616: 2611: 2606: 2595: 2590: 2585: 2580: 2465: 2460: 2366: 2358: 2350: 2287: 2282: 2277: 2272: 2148: 2143: 2138: 2133: 2128: 1132: 1944:
New DR, Maggirwar SB, Epstein LG, Dewhurst S, Gelbard HA (1998).
1839:
Raber J, Toggas SM, Lee S, Bloom FE, Epstein CJ, Mucke L (1996).
771: 767: 2374: 1164: 1160: 1119: 61: 2060: 501: 1983:, Standaert DG, Young AB, Harpold MM, Veliçelebi G (1998). 317: 2841: 482: 555:
extracellularly glutamate-gated ion channel activity
2755: 2742: 2702: 2637: 2567: 2555: 2533: 2383: 2333: 2159: 2111: 2102: 1402:King JE, Eugenin EA, Buckner CM, Berman JW (2006). 1135:) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A ( 1025: 1000: 974: 949: 1222: 1220: 1218: 1201: 1199: 1197: 264: 163: 677:negative regulation of protein catabolic process 702:ionotropic glutamate receptor signaling pathway 16:Protein-coding gene in the species Homo sapiens 1330: 1328: 1227:GRCm38: Ensembl release 89: ENSMUSG00000020734 2861: 2072: 757:protein localization to postsynaptic membrane 722:calcium ion transmembrane import into cytosol 8: 565:glutamate-gated calcium ion channel activity 1206:GRCh38: Ensembl release 89: ENSG00000161509 2868: 2854: 2752: 2564: 2108: 2079: 2065: 2057: 2047:United States National Library of Medicine 782: 517: 305: 204: 101: 2036:at the U.S. National Library of Medicine 2000: 1961: 1856: 1419: 1352: 752:excitatory chemical synaptic transmission 672:neuromuscular process controlling balance 636:NMDA selective glutamate receptor complex 2045:This article incorporates text from the 1903:Kurschner C, Mermelstein PG, Holden WT, 1313: 1311: 1193: 545:ionotropic glutamate receptor activity 18: 1335:Lim IA, Hall DD, Hell JW (Jun 2002). 1109:Glutamate receptor subunit epsilon-3 631:integral component of plasma membrane 269: 230: 225: 168: 127: 122: 7: 2822: 2820: 667:glutamate receptor signaling pathway 2002:10.1046/j.1471-4159.1998.71051953.x 1816:10.1111/j.1460-9568.1995.tb01048.x 1601:10.1111/j.1460-9568.1995.tb00649.x 1143:), NMDAR2C (GRIN2C), and NMDAR2D ( 1022: 997: 971: 946: 922: 903: 877: 858: 832: 813: 626:intracellular anatomical structure 487: 453:choroid plexus of fourth ventricle 405: 343: 322: 14: 1115:that in humans is encoded by the 742:regulation of synaptic plasticity 712:excitatory postsynaptic potential 2824: 1705:10.1097/00001756-199604100-00018 1668:10.1097/00002030-199605000-00003 727:regulation of molecular function 682:regulation of membrane potential 560:NMDA glutamate receptor activity 491: 253: 246: 240: 217: 152: 145: 139: 114: 2897:Ionotropic glutamate receptors 591:integral component of membrane 502:More reference expression data 471:More reference expression data 359:right hemisphere of cerebellum 1: 1888:10.1016/S0169-328X(96)00146-5 1559:Biochem. Biophys. Res. Commun 1459:10.1126/science.256.5060.1217 641:postsynaptic density membrane 238: 137: 2887:Genes on human chromosome 17 2840:. You can help Knowledge by 1779:10.1016/0006-8993(95)01197-8 1742:10.1016/0006-8993(95)01166-8 1639:10.1016/1055-8330(95)90021-7 1421:10.1016/j.micinf.2005.11.014 1404:"HIV tat and neurotoxicity" 570:signaling receptor activity 383:right lobe of thyroid gland 363:paraflocculus of cerebellum 2913: 2819: 1057:Chr 11: 115.14 – 115.16 Mb 717:calcium-mediated signaling 457:lateral geniculate nucleus 2639:Voltage- and ligand-gated 2096:ligand-gated ion channels 1876:Brain Res. Mol. Brain Res 1262:"Mouse PubMed Reference:" 1244:"Human PubMed Reference:" 1155:GRIN2C has been shown to 1095: 1090: 1086: 1079: 1063: 1044: 1029: 1004: 993: 978: 953: 942: 929: 925: 910: 906: 897: 884: 880: 865: 861: 852: 839: 835: 820: 816: 807: 792: 785: 781: 765: 520: 516: 499: 490: 481: 468: 417: 408: 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 2038:Medical Subject Headings 1963:10.1074/jbc.273.28.17852 1280:hybrid mapping panels". 1050:Chr 17: 74.84 – 74.86 Mb 2385:Nicotinic acetylcholine 1504:10.1126/science.7569905 550:cation channel activity 2892:Membrane protein stubs 2836:–related article is a 1921:10.1006/mcne.1998.0679 1858:10.1006/viro.1996.0664 1571:10.1006/bbrc.1993.2567 1354:10.1074/jbc.M112339200 1294:10.1006/geno.1997.5132 747:long-term potentiation 687:directional locomotion 2092:cell surface receptor 2034:GRIN2C+protein,+human 1533:10.1002/ana.410370314 646:glutamatergic synapse 596:postsynaptic membrane 441:medial dorsal nucleus 271:11 E2|11 80.8 cM 232:Chromosome 11 (mouse) 130:Chromosome 17 (human) 2757:Purinergic receptors 707:response to wounding 662:protein localization 606:postsynaptic density 535:ion channel activity 1909:Mol. Cell. Neurosci 1496:1995Sci...269.1737K 1451:1992Sci...256.1217M 2525:β1δε - Muscle type 2104:Cys-loop receptors 2049:, which is in the 1177:Glutamate receptor 887:ENSMUSG00000020734 655:Biological process 584:Cellular component 528:Molecular function 421:lobe of cerebellum 395:right frontal lobe 94:GRIN2C - orthologs 2849: 2848: 2814: 2813: 2810: 2809: 2738: 2737: 2569:Ligand-gated only 2551: 2550: 1627:Neurodegeneration 1490:(5231): 1737–40. 1445:(5060): 1217–21. 1347:(24): 21697–711. 1106: 1105: 1102: 1101: 1075: 1074: 1040: 1039: 1019: 1018: 989: 988: 968: 967: 938: 937: 919: 918: 893: 892: 874: 873: 848: 847: 829: 828: 777: 776: 737:brain development 512: 511: 508: 507: 477: 476: 464: 463: 433:perirhinal cortex 429:entorhinal cortex 425:cerebellar vermis 402: 401: 367:cerebellar vermis 300: 299: 199: 198: 2904: 2870: 2863: 2856: 2834:membrane protein 2828: 2821: 2753: 2565: 2109: 2081: 2074: 2067: 2058: 2022: 2004: 1981:Landwehrmeyer GB 1975: 1965: 1940: 1899: 1870: 1860: 1835: 1804:Eur. J. Neurosci 1798: 1761: 1724: 1687: 1650: 1620: 1589:Eur. J. Neurosci 1582: 1552: 1515: 1478: 1433: 1423: 1398: 1367: 1366: 1356: 1332: 1323: 1322: 1315: 1306: 1305: 1276: 1270: 1269: 1258: 1252: 1251: 1240: 1234: 1224: 1213: 1203: 1088: 1087: 1059: 1052: 1035: 1023: 1014: 998: 994:RefSeq (protein) 984: 972: 963: 947: 923: 904: 878: 859: 833: 814: 783: 518: 504: 495: 488: 473: 413: 411:Top expressed in 406: 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 47: 40: 19: 2912: 2911: 2907: 2906: 2905: 2903: 2902: 2901: 2877: 2876: 2875: 2874: 2817: 2815: 2806: 2734: 2728: 2720: 2698: 2633: 2547: 2529: 2524: 2516:- Ganglion type 2515: 2511: 2503: 2495: 2491: 2483: 2479: 2379: 2370: 2362: 2354: 2346: 2329: 2323: 2315: 2307: 2298: 2268: 2260: 2252: 2244: 2236: 2228: 2220: 2212: 2204: 2196: 2188: 2180: 2172: 2155: 2124: 2098: 2085: 2030: 2025: 1978: 1956:(28): 17852–8. 1943: 1902: 1873: 1838: 1801: 1764: 1736:(1–2): 168–76. 1727: 1690: 1653: 1623: 1595:(11): 2285–93. 1585: 1555: 1518: 1481: 1436: 1408:Microbes Infect 1401: 1383:Neurotoxicology 1380: 1376: 1374:Further reading 1371: 1370: 1334: 1333: 1326: 1317: 1316: 1309: 1278: 1277: 1273: 1260: 1259: 1255: 1242: 1241: 1237: 1225: 1216: 1204: 1195: 1190: 1173: 1153: 1128: 1097:View/Edit Mouse 1092:View/Edit Human 1055: 1048: 1045:Location (UCSC) 1031: 1010: 1006: 980: 959: 955: 868:ENSG00000161509 761: 650: 611:plasma membrane 579: 540:protein binding 500: 469: 460: 455: 451: 447: 443: 439: 435: 431: 427: 423: 409: 398: 393: 391:caudate nucleus 389: 385: 381: 377: 373: 369: 365: 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 2910: 2908: 2900: 2899: 2894: 2889: 2879: 2878: 2873: 2872: 2865: 2858: 2850: 2847: 2846: 2829: 2812: 2811: 2808: 2807: 2805: 2804: 2803: 2802: 2797: 2792: 2787: 2782: 2777: 2772: 2761: 2759: 2750: 2748:gated channels 2740: 2739: 2736: 2735: 2733: 2732: 2731: 2730: 2726: 2722: 2718: 2708: 2706: 2700: 2699: 2697: 2696: 2695: 2694: 2689: 2684: 2679: 2674: 2669: 2664: 2659: 2654: 2643: 2641: 2635: 2634: 2632: 2631: 2630: 2629: 2624: 2619: 2614: 2609: 2599: 2593: 2588: 2583: 2573: 2571: 2562: 2553: 2552: 2549: 2548: 2546: 2545: 2543:Zinc-activated 2539: 2537: 2531: 2530: 2528: 2527: 2522: 2518: 2513: 2509: 2505: 2501: 2497: 2493: 2489: 2485: 2481: 2477: 2469: 2468: 2463: 2458: 2453: 2448: 2443: 2438: 2433: 2428: 2423: 2418: 2413: 2408: 2403: 2398: 2389: 2387: 2381: 2380: 2378: 2377: 2372: 2368: 2364: 2360: 2356: 2352: 2348: 2344: 2339: 2337: 2331: 2330: 2328: 2327: 2326: 2325: 2321: 2317: 2313: 2309: 2305: 2296: 2292: 2291: 2290: 2285: 2280: 2275: 2270: 2266: 2262: 2258: 2254: 2250: 2246: 2242: 2238: 2234: 2230: 2226: 2222: 2218: 2214: 2210: 2206: 2202: 2198: 2194: 2190: 2186: 2182: 2178: 2170: 2165: 2163: 2157: 2156: 2154: 2153: 2152: 2151: 2146: 2141: 2136: 2131: 2122: 2117: 2115: 2113:5-HT/serotonin 2106: 2100: 2099: 2086: 2084: 2083: 2076: 2069: 2061: 2042: 2041: 2029: 2028:External links 2026: 2024: 2023: 1995:(5): 1953–68. 1976: 1941: 1900: 1882:(1–2): 57–64. 1871: 1836: 1810:(12): 2502–7. 1799: 1762: 1725: 1688: 1651: 1621: 1583: 1553: 1516: 1479: 1434: 1414:(5): 1347–57. 1399: 1389:(4–5): 683–8. 1377: 1375: 1372: 1369: 1368: 1324: 1307: 1271: 1253: 1235: 1214: 1192: 1191: 1189: 1186: 1185: 1184: 1179: 1172: 1169: 1152: 1149: 1127: 1124: 1104: 1103: 1100: 1099: 1094: 1084: 1083: 1077: 1076: 1073: 1072: 1070: 1068: 1061: 1060: 1053: 1046: 1042: 1041: 1038: 1037: 1027: 1026: 1020: 1017: 1016: 1002: 1001: 995: 991: 990: 987: 986: 976: 975: 969: 966: 965: 951: 950: 944: 940: 939: 936: 935: 927: 926: 920: 917: 916: 908: 907: 901: 895: 894: 891: 890: 882: 881: 875: 872: 871: 863: 862: 856: 850: 849: 846: 845: 837: 836: 830: 827: 826: 818: 817: 811: 805: 804: 799: 794: 790: 789: 779: 778: 775: 774: 763: 762: 760: 759: 754: 749: 744: 739: 734: 729: 724: 719: 714: 709: 704: 699: 694: 689: 684: 679: 674: 669: 664: 658: 656: 652: 651: 649: 648: 643: 638: 633: 628: 623: 618: 613: 608: 603: 598: 593: 587: 585: 581: 580: 578: 577: 572: 567: 562: 557: 552: 547: 542: 537: 531: 529: 525: 524: 514: 513: 510: 509: 506: 505: 497: 496: 485: 479: 478: 475: 474: 466: 465: 462: 461: 459: 458: 454: 450: 449:granular layer 446: 442: 438: 434: 430: 426: 422: 418: 415: 414: 403: 400: 399: 397: 396: 392: 388: 384: 380: 376: 372: 368: 364: 360: 356: 353: 352: 340: 339: 331: 320: 314: 313: 310:RNA expression 302: 301: 298: 297: 289: 285: 284: 276: 273: 268: 262: 261: 252: 245: 239: 235: 234: 229: 223: 222: 214: 213: 201: 200: 197: 196: 188: 184: 183: 175: 172: 167: 161: 160: 151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2909: 2898: 2895: 2893: 2890: 2888: 2885: 2884: 2882: 2871: 2866: 2864: 2859: 2857: 2852: 2851: 2845: 2843: 2839: 2835: 2830: 2827: 2823: 2818: 2801: 2798: 2796: 2793: 2791: 2788: 2786: 2783: 2781: 2778: 2776: 2773: 2771: 2768: 2767: 2766: 2763: 2762: 2760: 2758: 2754: 2751: 2749: 2745: 2741: 2729: 2723: 2721: 2715: 2714: 2713: 2710: 2709: 2707: 2705: 2701: 2693: 2690: 2688: 2685: 2683: 2680: 2678: 2675: 2673: 2670: 2668: 2665: 2663: 2660: 2658: 2655: 2653: 2650: 2649: 2648: 2645: 2644: 2642: 2640: 2636: 2628: 2625: 2623: 2620: 2618: 2615: 2613: 2610: 2608: 2605: 2604: 2603: 2600: 2597: 2594: 2592: 2589: 2587: 2584: 2582: 2578: 2575: 2574: 2572: 2570: 2566: 2563: 2561: 2558: 2554: 2544: 2541: 2540: 2538: 2536: 2532: 2526: 2519: 2517: 2506: 2504: 2498: 2496: 2486: 2484: 2474: 2471: 2470: 2467: 2464: 2462: 2459: 2457: 2454: 2452: 2449: 2447: 2444: 2442: 2439: 2437: 2434: 2432: 2429: 2427: 2424: 2422: 2419: 2417: 2414: 2412: 2409: 2407: 2404: 2402: 2399: 2397: 2394: 2391: 2390: 2388: 2386: 2382: 2376: 2373: 2371: 2365: 2363: 2357: 2355: 2349: 2347: 2341: 2340: 2338: 2336: 2332: 2324: 2318: 2316: 2310: 2308: 2302: 2301: 2300: 2293: 2289: 2286: 2284: 2281: 2279: 2276: 2274: 2271: 2269: 2263: 2261: 2255: 2253: 2247: 2245: 2239: 2237: 2231: 2229: 2223: 2221: 2215: 2213: 2207: 2205: 2199: 2197: 2191: 2189: 2183: 2181: 2175: 2174: 2173: 2167: 2166: 2164: 2162: 2158: 2150: 2147: 2145: 2142: 2140: 2137: 2135: 2132: 2130: 2127: 2126: 2125: 2119: 2118: 2116: 2114: 2110: 2107: 2105: 2101: 2097: 2093: 2089: 2082: 2077: 2075: 2070: 2068: 2063: 2062: 2059: 2055: 2054: 2052: 2051:public domain 2048: 2039: 2035: 2032: 2031: 2027: 2020: 2016: 2012: 2008: 2003: 1998: 1994: 1990: 1986: 1982: 1977: 1973: 1969: 1964: 1959: 1955: 1951: 1950:J. Biol. Chem 1947: 1942: 1938: 1934: 1930: 1926: 1922: 1918: 1915:(3): 161–72. 1914: 1910: 1906: 1901: 1897: 1893: 1889: 1885: 1881: 1877: 1872: 1868: 1864: 1859: 1854: 1851:(2): 362–73. 1850: 1846: 1842: 1837: 1833: 1829: 1825: 1821: 1817: 1813: 1809: 1805: 1800: 1796: 1792: 1788: 1784: 1780: 1776: 1772: 1768: 1763: 1759: 1755: 1751: 1747: 1743: 1739: 1735: 1731: 1726: 1722: 1718: 1714: 1710: 1706: 1702: 1699:(5): 1045–9. 1698: 1694: 1689: 1685: 1681: 1677: 1673: 1669: 1665: 1661: 1657: 1652: 1648: 1644: 1640: 1636: 1633:(3): 315–21. 1632: 1628: 1622: 1618: 1614: 1610: 1606: 1602: 1598: 1594: 1590: 1584: 1580: 1576: 1572: 1568: 1564: 1560: 1554: 1550: 1546: 1542: 1538: 1534: 1530: 1527:(3): 373–80. 1526: 1522: 1517: 1513: 1509: 1505: 1501: 1497: 1493: 1489: 1485: 1480: 1476: 1472: 1468: 1464: 1460: 1456: 1452: 1448: 1444: 1440: 1435: 1431: 1427: 1422: 1417: 1413: 1409: 1405: 1400: 1396: 1392: 1388: 1384: 1379: 1378: 1373: 1364: 1360: 1355: 1350: 1346: 1342: 1341:J. Biol. Chem 1338: 1331: 1329: 1325: 1320: 1314: 1312: 1308: 1303: 1299: 1295: 1291: 1287: 1283: 1275: 1272: 1267: 1263: 1257: 1254: 1249: 1245: 1239: 1236: 1232: 1228: 1223: 1221: 1219: 1215: 1211: 1207: 1202: 1200: 1198: 1194: 1187: 1183: 1182:NMDA receptor 1180: 1178: 1175: 1174: 1170: 1168: 1166: 1162: 1158: 1150: 1148: 1146: 1142: 1138: 1134: 1125: 1123: 1121: 1118: 1114: 1110: 1098: 1093: 1089: 1085: 1082: 1078: 1071: 1069: 1066: 1062: 1058: 1054: 1051: 1047: 1043: 1036: 1034: 1028: 1024: 1021: 1015: 1013: 1009: 1003: 999: 996: 992: 985: 983: 977: 973: 970: 964: 962: 958: 952: 948: 945: 943:RefSeq (mRNA) 941: 934: 933: 928: 924: 921: 915: 914: 909: 905: 902: 900: 896: 889: 888: 883: 879: 876: 870: 869: 864: 860: 857: 855: 851: 844: 843: 838: 834: 831: 825: 824: 819: 815: 812: 810: 806: 803: 800: 798: 795: 791: 788: 784: 780: 773: 769: 764: 758: 755: 753: 750: 748: 745: 743: 740: 738: 735: 733: 730: 728: 725: 723: 720: 718: 715: 713: 710: 708: 705: 703: 700: 698: 695: 693: 692:ion transport 690: 688: 685: 683: 680: 678: 675: 673: 670: 668: 665: 663: 660: 659: 657: 654: 653: 647: 644: 642: 639: 637: 634: 632: 629: 627: 624: 622: 621:cell junction 619: 617: 614: 612: 609: 607: 604: 602: 599: 597: 594: 592: 589: 588: 586: 583: 582: 576: 573: 571: 568: 566: 563: 561: 558: 556: 553: 551: 548: 546: 543: 541: 538: 536: 533: 532: 530: 527: 526: 523: 522:Gene ontology 519: 515: 503: 498: 494: 489: 486: 484: 480: 472: 467: 456: 452: 448: 445:visual cortex 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 394: 390: 386: 382: 378: 375:right auricle 374: 371:parotid gland 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 2842:expanding it 2831: 2816: 2747: 2711: 2703: 2666: 2638: 2568: 2534: 2472: 2392: 2044: 2043: 1992: 1989:J. Neurochem 1988: 1953: 1949: 1912: 1908: 1879: 1875: 1848: 1844: 1807: 1803: 1773:(2): 303–7. 1770: 1766: 1733: 1729: 1696: 1692: 1662:(5): 463–8. 1659: 1655: 1630: 1626: 1592: 1588: 1565:(2): 922–6. 1562: 1558: 1524: 1520: 1487: 1483: 1442: 1438: 1411: 1407: 1386: 1382: 1344: 1340: 1288:(3): 423–5. 1285: 1281: 1274: 1265: 1256: 1247: 1238: 1154: 1151:Interactions 1139:), NMDAR2B ( 1129: 1116: 1108: 1107: 1030: 1012:NP_001265482 1005: 979: 961:NM_001278553 954: 930: 911: 885: 866: 840: 821: 801: 796: 697:MAPK cascade 333: 326: 292:115,158,069 279:115,139,995 53:External IDs 2088:Ion channel 1905:Surmeier DJ 1693:NeuroReport 1521:Ann. Neurol 191:74,861,504 178:74,842,023 31:Identifiers 2881:Categories 2560:glutamates 2557:Ionotropic 2473:pentamers: 1233:, May 2017 1212:, May 2017 1188:References 337:(ortholog) 74:HomoloGene 2393:monomers: 1767:Brain Res 1730:Brain Res 1033:NP_034480 1008:NP_000826 982:NM_010350 957:NM_000835 787:Orthologs 732:transport 437:CA3 field 82:GeneCards 2704:‘Orphan’ 2019:21368815 1937:36534759 1845:Virology 1795:44260060 1758:32822686 1721:21018147 1617:27201873 1549:24405132 1430:16697675 1363:11937501 1282:Genomics 1229:– 1208:– 1171:See also 1157:interact 1126:Function 1081:Wikidata 766:Sources: 601:membrane 387:amygdala 2602:Kainate 2335:Glycine 2011:9798920 1972:9651389 1929:9647694 1896:9037519 1867:8955056 1832:7370984 1824:8845955 1787:8822372 1750:8821747 1713:8804048 1684:1669986 1676:8724036 1647:8581564 1609:8563977 1579:8267632 1541:7695237 1512:7569905 1492:Bibcode 1484:Science 1467:1350383 1447:Bibcode 1439:Science 1395:9745929 1302:9480759 1231:Ensembl 1210:Ensembl 1113:protein 899:UniProt 854:Ensembl 793:Species 772:QuickGO 616:synapse 379:putamen 312:pattern 170:17q25.1 38:Aliases 2040:(MeSH) 2017:  2009:  1970:  1935:  1927:  1894:  1865:  1830:  1822:  1793:  1785:  1756:  1748:  1719:  1711:  1682:  1674:  1645:  1615:  1607:  1577:  1547:  1539:  1510:  1475:989677 1473:  1465:  1428:  1393:  1361:  1300:  1145:GRIN2D 1141:GRIN2B 1137:GRIN2A 1117:GRIN2C 1067:search 1065:PubMed 932:Q01098 913:Q14957 809:Entrez 483:BioGPS 86:GRIN2C 62:138254 45:GRIN2C 22:GRIN2C 2832:This 2015:S2CID 1933:S2CID 1828:S2CID 1791:S2CID 1754:S2CID 1717:S2CID 1680:S2CID 1613:S2CID 1545:S2CID 1471:S2CID 1159:with 1133:GRIN1 1111:is a 842:14813 802:Mouse 797:Human 768:Amigo 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 70:95822 2838:stub 2712:GluD 2647:NMDA 2577:AMPA 2535:Zinc 2521:(α1) 2512:(β4) 2508:(α1) 2500:(α7) 2492:(β2) 2488:(α4) 2480:(β4) 2476:(α3) 2295:GABA 2169:GABA 2161:GABA 2121:5-HT 2007:PMID 1968:PMID 1925:PMID 1892:PMID 1863:PMID 1820:PMID 1783:PMID 1746:PMID 1709:PMID 1672:PMID 1656:AIDS 1643:PMID 1605:PMID 1575:PMID 1537:PMID 1508:PMID 1463:PMID 1426:PMID 1391:PMID 1359:PMID 1298:PMID 1165:DLG3 1163:and 1161:DLG4 1120:gene 823:2905 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 58:OMIM 2765:P2X 2744:ATP 2692:L1B 2687:L1A 2436:α10 1997:doi 1958:doi 1954:273 1917:doi 1884:doi 1853:doi 1849:226 1812:doi 1775:doi 1771:706 1738:doi 1734:705 1701:doi 1664:doi 1635:doi 1597:doi 1567:doi 1563:197 1529:doi 1500:doi 1488:269 1455:doi 1443:256 1416:doi 1349:doi 1345:277 1290:doi 1147:). 288:End 187:End 90:OMA 78:647 66:MGI 2883:: 2682:3B 2677:3A 2672:2D 2667:2C 2662:2B 2657:2A 2456:β4 2451:β3 2446:β2 2441:β1 2431:α9 2426:α7 2421:α6 2416:α5 2411:α4 2406:α3 2401:α2 2396:α1 2299:-ρ 2094:: 2090:, 2013:. 2005:. 1993:71 1991:. 1987:. 1966:. 1952:. 1948:. 1931:. 1923:. 1913:11 1911:. 1890:. 1880:43 1878:. 1861:. 1847:. 1843:. 1826:. 1818:. 1806:. 1789:. 1781:. 1769:. 1752:. 1744:. 1732:. 1715:. 1707:. 1695:. 1678:. 1670:. 1660:10 1658:. 1641:. 1629:. 1611:. 1603:. 1591:. 1573:. 1561:. 1543:. 1535:. 1525:37 1523:. 1506:. 1498:. 1486:. 1469:. 1461:. 1453:. 1441:. 1424:. 1410:. 1406:. 1387:19 1385:. 1357:. 1343:. 1339:. 1327:^ 1310:^ 1296:. 1286:47 1284:. 1264:. 1246:. 1217:^ 1196:^ 1167:. 1122:. 770:/ 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 2869:e 2862:t 2855:v 2844:. 2800:7 2795:6 2790:5 2785:4 2780:3 2775:2 2770:1 2746:- 2727:2 2725:δ 2719:1 2717:δ 2652:1 2627:5 2622:4 2617:3 2612:2 2607:1 2598:) 2596:4 2591:3 2586:2 2581:1 2579:( 2523:2 2514:3 2510:2 2502:5 2494:3 2490:2 2482:3 2478:2 2466:ε 2461:δ 2375:β 2369:4 2367:α 2361:3 2359:α 2353:2 2351:α 2345:1 2343:α 2322:3 2320:ρ 2314:2 2312:ρ 2306:1 2304:ρ 2297:A 2288:θ 2283:π 2278:ε 2273:δ 2267:3 2265:γ 2259:2 2257:γ 2251:1 2249:γ 2243:3 2241:β 2235:2 2233:β 2227:1 2225:β 2219:6 2217:α 2211:5 2209:α 2203:4 2201:α 2195:3 2193:α 2187:2 2185:α 2179:1 2177:α 2171:A 2149:E 2144:D 2139:C 2134:B 2129:A 2123:3 2080:e 2073:t 2066:v 2053:. 2021:. 1999:: 1974:. 1960:: 1939:. 1919:: 1898:. 1886:: 1869:. 1855:: 1834:. 1814:: 1808:7 1797:. 1777:: 1760:. 1740:: 1723:. 1703:: 1697:7 1686:. 1666:: 1649:. 1637:: 1631:4 1619:. 1599:: 1593:7 1581:. 1569:: 1551:. 1531:: 1514:. 1502:: 1494:: 1477:. 1457:: 1449:: 1432:. 1418:: 1412:8 1397:. 1365:. 1351:: 1321:. 1304:. 1292:: 1268:. 1250:. 212:) 109:) 92::

Index

Aliases
GRIN2C
OMIM
138254
MGI
95822
HomoloGene
647
GeneCards
GRIN2C
OMA
GRIN2C - orthologs
Human
Chromosome 17 (human)
Chr.
Chromosome 17 (human)
Chromosome 17 (human)
Genomic location for GRIN2C
Genomic location for GRIN2C
Band
bp
bp
Mouse
Chromosome 11 (mouse)
Chr.
Chromosome 11 (mouse)
Genomic location for GRIN2C
Genomic location for GRIN2C
Band
bp

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.