269:
29:
936:
Toral M, GĆ³mez-GuzmĆ”n M, JimĆ©nez R, Romero M, Zarzuelo MJ, Utrilla MP, Hermenegildo C, Cogolludo Ć, PĆ©rez-VizcaĆno F, GĆ”lvez J, Duarte J (September 2015). "Chronic peroxisome proliferator-activated receptorĪ²/Ī“ agonist GW0742 prevents hypertension, vascular inflammatory and oxidative status, and
620:
Sznaidman ML, Haffner CD, Maloney PR, Fivush A, Chao E, Goreham D, Sierra ML, LeGrumelec C, Xu HE, Montana VG, Lambert MH, Willson TM, Oliver WR, Sternbach DD (May 2003). "Novel selective small molecule agonists for peroxisome proliferator-activated receptor Ī“ (PPARĪ“)--synthesis and biological
895:
Paterniti I, Mazzon E, Riccardi L, Galuppo M, Impellizzeri D, Esposito E, Bramanti P, Cappellani A, Cuzzocrea S (July 2012). "Peroxisome proliferator-activated receptor Ī²/Ī“ agonist GW0742 ameliorates cerulein- and taurocholate-induced acute pancreatitis in mice".
1081:
Haskova Z, Hoang B, Luo G, Morgan LA, Billin AN, Barone FC, Shearer BG, Barton ME, Kilgore KS (July 2008). "Modulation of LPS-induced pulmonary neutrophil infiltration and cytokine production by the selective PPARbeta/delta ligand GW0742".
472:
GW0742 has been shown to ameliorate experimentally induced pancreatitis in mice. Additionally, it prevents hypertension in diet induced obese mice, has been investigated as potential antidiabetic drug, and has anti-inflammatory effects.
576:
Haskova Z, Hoang B, Luo G, Morgan LA, Billin AN, Barone FC, et al. (July 2008). "Modulation of LPS-induced pulmonary neutrophil infiltration and cytokine production by the selective PPARbeta/delta ligand GW0742".
1035:
Di Paola R, Esposito E, Mazzon E, Paterniti I, Galuppo M, Cuzzocrea S (August 2010). "GW0742, a selective PPAR-beta/delta agonist, contributes to the resolution of inflammation after gut ischemia/reperfusion injury".
532:
Smith SA, Monteith GR, Robinson JA, Venkata NG, May FJ, Roberts-Thomson SJ (July 2004). "Effect of the peroxisome proliferator-activated receptor beta activator GW0742 in rat cultured cerebellar granule neurons".
806:
Perez Diaz N, Zloh M, Patel P, Mackenzie LS (January 2016). "In silico modelling of prostacyclin and other lipid mediators to nuclear receptors reveal novel thyroid hormone receptor antagonist properties".
700:
Nandhikonda P, Yasgar A, Baranowski AM, Sidhu PS, McCallum MM, Pawlak AJ, Teske K, Feleke B, Yuan NY, Kevin C, Bikle DD, Ayers SD, Webb P, Rai G, Simeonov A, Jadhav A, Maloney D, Arnold LA (June 2013).
460:
Multiple derivatives of GW0742 core structure have been developed. One of the compounds has the thiazole ring replaced with an oxazole ring inhibited VDR-meditated transcription with IC
41:
351:
443:
It is mixed PPAR-B agonist antagonist depending on its dosage. It has weak activity on multiple nuclear receptors as well. It is antagonistic at androgen receptors and
1509:
1388:
1169:
365:
761:
1153:
492:
420:
393:
InChI=InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)
1144:
1962:
703:"Peroxisome proliferation-activated receptor Ī“ agonist GW0742 interacts weakly with multiple nuclear receptors, including the vitamin D receptor"
658:"Peroxisome proliferator-activated receptor beta stimulation induces rapid cardiac growth and angiogenesis via direct activation of calcineurin"
988:
1972:
1548:
1535:
1409:
1190:
1982:
385:
809:
1525:
86:
62:
1543:
1404:
1185:
1137:
844:
Teske KA, Rai G, Nandhikonda P, Sidhu PS, Feleke B, Simeonov A, Yasgar A, Jadhav A, Maloney DJ, Arnold LA (October 2017).
1940:
1804:
1794:
1038:
188:
1977:
464:
of 660 nM. Other novel analogues which are more potent than GWO742 with reduced toxicity have been developed as well.
248:
1122:
1479:
1353:
850:
1130:
157:
939:
1967:
1718:
1530:
1328:
1323:
1235:
1992:
1313:
1084:
237:
148:
1728:
511:
1200:
846:"Parallel Chemistry Approach to Identify Novel Nuclear Receptor Ligands Based on the GW0742 Scaffold"
1997:
1844:
1563:
264:
103:
1766:
1736:
1713:
1708:
1693:
1608:
1583:
1987:
1703:
1648:
1613:
1161:
1109:
1063:
964:
602:
558:
444:
1741:
1434:
1849:
1673:
1668:
1663:
1464:
1454:
1293:
1288:
1225:
1499:
1494:
1363:
1308:
1101:
1055:
1017:
956:
915:
877:
826:
788:
734:
679:
656:
Wagner N, Jehl-PiƩtri C, Lopez P, Murdaca J, Giordano C, Schwartz C, et al. (July 2009).
638:
594:
550:
1859:
1839:
1819:
1814:
1638:
1373:
1270:
177:
1834:
1824:
1756:
1688:
1558:
1489:
1414:
1205:
1093:
1047:
1007:
997:
948:
907:
867:
859:
818:
778:
770:
724:
716:
669:
630:
586:
542:
285:
112:
197:
427:
268:
822:
1280:
1012:
983:
872:
845:
783:
756:
729:
702:
634:
1956:
1918:
1908:
1771:
1751:
1746:
1698:
1678:
1474:
1343:
1298:
1113:
1067:
968:
606:
562:
137:
1883:
1878:
1786:
1781:
1761:
1723:
1683:
1658:
1653:
1603:
1459:
1358:
1348:
1338:
1333:
1303:
1275:
707:
952:
1913:
1903:
1893:
1776:
1628:
1618:
1593:
1588:
1578:
1573:
1553:
1429:
1419:
1318:
1265:
1255:
1245:
1215:
1210:
1195:
487:
447:. In silico modelling suggest that it has effects on thyroid hormone receptors.
911:
863:
774:
1923:
1898:
1888:
1469:
1239:
1220:
1097:
590:
327:
168:
28:
1643:
1633:
1568:
1449:
1439:
1260:
1105:
1059:
1021:
984:"Development of PPAR-agonist GW0742 as antidiabetic drug: study in animals"
960:
919:
881:
830:
792:
738:
683:
642:
598:
554:
1623:
1598:
1424:
1250:
1230:
674:
482:
1510:
1389:
1170:
1051:
1002:
1809:
1444:
898:
423:
123:
20:
720:
546:
1378:
228:
657:
217:
1154:
350:
341:
208:
94:-4-methyl-5-thiazolyl]methyl]thio]-2-methyl phenoxy]-acetic acid
1126:
253:
1515:
Tooltip
Peroxisome proliferator-activated receptor gamma
1394:
Tooltip
Peroxisome proliferator-activated receptor delta
1175:
Tooltip
Peroxisome proliferator-activated receptor alpha
373:
FC(F)(F)c3c(F)cc(c1nc(c(s1)CSc2cc(c(OCC(=O)O)cc2)C)C)cc3
757:"Novel VDR antagonists based on the GW0742 scaffold"
1868:
1508:
1387:
1168:
339:
326:
284:
279:
247:
227:
207:
187:
167:
156:
147:
122:
102:
77:
61:
56:
40:
35:
1159:Tooltip Peroxisome proliferator-activated receptor
937:endothelial dysfunction in diet-induced obesity".
1795:
982:Niu HS, Ku PM, Niu CS, Cheng JT, Lee KS (2015).
755:Teske KA, Bogart JW, Arnold LA (February 2018).
136:
931:
929:
111:
750:
748:
695:
693:
1138:
8:
762:Bioorganic & Medicinal Chemistry Letters
623:Bioorganic & Medicinal Chemistry Letters
19:
426:that has been investigated for drug use by
1145:
1131:
1123:
810:Prostaglandins & Other Lipid Mediators
493:Peroxisome proliferator-activated receptor
267:
176:
27:
1011:
1001:
871:
782:
728:
673:
196:
503:
390:
370:
263:
91:
18:
236:
7:
989:Drug Design, Development and Therapy
823:10.1016/j.prostaglandins.2015.12.002
216:
127:
16:PPAR Ī²/Ī“ receptor Agonist compound
14:
1800:Tooltip Selective PPARĪ³ modulator
535:Journal of Neuroscience Research
308:
302:
296:
398:Key:HWVNEWGKWRGSRK-UHFFFAOYSA-N
1963:Drugs not assigned an ATC code
317:
311:
290:
1:
1941:Receptor/signaling modulators
635:10.1016/s0960-894x(03)00207-5
1039:Journal of Leukocyte Biology
953:10.1097/HJH.0000000000000634
1684:Muraglitazar (muroglitazar)
2014:
1973:Drugs developed by GSK plc
1536:15-Deoxy-Ī-prostaglandin J
912:10.1016/j.surg.2012.02.004
864:10.1021/acscombsci.7b00066
775:10.1016/j.bmcl.2017.12.041
280:Chemical and physical data
1983:Trifluoromethyl compounds
1932:
1480:Tetradecylthioacetic acid
1354:Tetradecylthioacetic acid
1098:10.1007/s00011-007-7157-4
851:ACS Combinatorial Science
591:10.1007/s00011-007-7157-4
381:
361:
82:
26:
512:"Cayman Chemical GW0742"
940:Journal of Hypertension
662:Cardiovascular Research
1719:Perfluorononanoic acid
1329:Perfluorooctanoic acid
1324:Perfluorononanoic acid
1314:Palmitoylethanolamide
1085:Inflammation Research
579:Inflammation Research
1531:5-Oxo-15-hydroxy-ETE
1201:Aluminium clofibrate
1052:10.1189/jlb.0110053
1003:10.2147/DDDT.S95045
23:
1978:Experimental drugs
675:10.1093/cvr/cvp106
1950:
1949:
1309:Oleylethanolamide
721:10.1021/bi400321p
547:10.1002/jnr.20153
406:
405:
352:Interactive image
249:CompTox Dashboard
2005:
1801:
1797:
1559:Arachidonic acid
1516:
1512:
1415:Arachidonic acid
1395:
1391:
1206:Arachidonic acid
1176:
1172:
1160:
1156:
1147:
1140:
1133:
1124:
1118:
1117:
1078:
1072:
1071:
1032:
1026:
1025:
1015:
1005:
979:
973:
972:
933:
924:
923:
892:
886:
885:
875:
841:
835:
834:
803:
797:
796:
786:
752:
743:
742:
732:
715:(24): 4193ā203.
697:
688:
687:
677:
653:
647:
646:
617:
611:
610:
573:
567:
566:
529:
523:
522:
520:
518:
508:
439:Pharmacodynamics
354:
334:
319:
313:
310:
304:
298:
292:
272:
271:
257:
255:
240:
220:
200:
180:
160:
140:
130:
129:
115:
31:
24:
22:
2013:
2012:
2008:
2007:
2006:
2004:
2003:
2002:
1953:
1952:
1951:
1946:
1928:
1864:
1799:
1732:
1729:Prostaglandin J
1539:
1514:
1504:
1393:
1383:
1284:
1174:
1164:
1158:
1151:
1121:
1080:
1079:
1075:
1034:
1033:
1029:
981:
980:
976:
935:
934:
927:
894:
893:
889:
858:(10): 646ā656.
843:
842:
838:
805:
804:
800:
754:
753:
746:
699:
698:
691:
655:
654:
650:
619:
618:
614:
575:
574:
570:
531:
530:
526:
516:
514:
510:
509:
505:
501:
479:
470:
463:
458:
453:
441:
436:
428:GlaxoSmithKline
411:(also known as
402:
399:
394:
389:
388:
377:
374:
369:
368:
357:
332:
322:
316:
307:
301:
295:
275:
251:
243:
223:
203:
183:
163:
143:
126:
118:
98:
95:
90:
89:
73:
70:Investigational
52:
17:
12:
11:
5:
2011:
2009:
2001:
2000:
1995:
1990:
1985:
1980:
1975:
1970:
1965:
1955:
1954:
1948:
1947:
1945:
1944:
1937:
1933:
1930:
1929:
1927:
1926:
1921:
1916:
1911:
1906:
1901:
1896:
1891:
1886:
1881:
1872:
1870:
1866:
1865:
1863:
1862:
1853:
1852:
1847:
1842:
1837:
1828:
1827:
1822:
1817:
1812:
1807:
1790:
1789:
1784:
1779:
1774:
1769:
1764:
1759:
1754:
1749:
1744:
1739:
1734:
1730:
1726:
1721:
1716:
1711:
1706:
1701:
1696:
1691:
1686:
1681:
1676:
1671:
1666:
1661:
1656:
1651:
1646:
1641:
1636:
1631:
1626:
1621:
1616:
1611:
1606:
1601:
1596:
1591:
1586:
1581:
1576:
1571:
1566:
1561:
1556:
1551:
1546:
1541:
1537:
1533:
1528:
1519:
1517:
1506:
1505:
1503:
1502:
1497:
1492:
1483:
1482:
1477:
1472:
1467:
1462:
1457:
1452:
1447:
1442:
1437:
1432:
1427:
1422:
1417:
1412:
1407:
1398:
1396:
1385:
1384:
1382:
1381:
1376:
1367:
1366:
1361:
1356:
1351:
1346:
1341:
1336:
1331:
1326:
1321:
1316:
1311:
1306:
1301:
1296:
1291:
1286:
1282:
1278:
1273:
1268:
1263:
1258:
1253:
1248:
1243:
1242:) (in rodents)
1233:
1228:
1223:
1218:
1213:
1208:
1203:
1198:
1193:
1188:
1179:
1177:
1166:
1165:
1152:
1150:
1149:
1142:
1135:
1127:
1120:
1119:
1073:
1046:(2): 291ā301.
1027:
974:
947:(9): 1831ā44.
925:
887:
836:
798:
769:(3): 351ā354.
744:
689:
648:
629:(9): 1517ā21.
612:
568:
524:
502:
500:
497:
496:
495:
490:
485:
478:
475:
469:
466:
461:
457:
454:
452:
449:
440:
437:
435:
432:
404:
403:
401:
400:
397:
395:
392:
384:
383:
382:
379:
378:
376:
375:
372:
364:
363:
362:
359:
358:
356:
355:
347:
345:
337:
336:
330:
324:
323:
320:
314:
305:
299:
293:
288:
282:
281:
277:
276:
274:
273:
260:
258:
245:
244:
242:
241:
233:
231:
225:
224:
222:
221:
213:
211:
205:
204:
202:
201:
193:
191:
185:
184:
182:
181:
173:
171:
165:
164:
162:
161:
153:
151:
145:
144:
142:
141:
133:
131:
120:
119:
117:
116:
108:
106:
100:
99:
97:
96:
93:
85:
84:
83:
80:
79:
75:
74:
72:
71:
67:
65:
59:
58:
54:
53:
51:
50:
46:
44:
38:
37:
33:
32:
15:
13:
10:
9:
6:
4:
3:
2:
2010:
1999:
1996:
1994:
1991:
1989:
1986:
1984:
1981:
1979:
1976:
1974:
1971:
1969:
1968:PPAR agonists
1966:
1964:
1961:
1960:
1958:
1943:
1942:
1938:
1935:
1934:
1931:
1925:
1922:
1920:
1919:Rivoglitazone
1917:
1915:
1912:
1910:
1909:Netoglitazone
1907:
1905:
1902:
1900:
1897:
1895:
1892:
1890:
1887:
1885:
1882:
1880:
1877:
1874:
1873:
1871:
1869:Non-selective
1867:
1861:
1858:
1855:
1854:
1851:
1848:
1846:
1843:
1841:
1838:
1836:
1833:
1830:
1829:
1826:
1823:
1821:
1818:
1816:
1813:
1811:
1808:
1806:
1803:
1798:
1792:
1791:
1788:
1785:
1783:
1780:
1778:
1775:
1773:
1772:Sodelglitazar
1770:
1768:
1765:
1763:
1760:
1758:
1755:
1753:
1752:Rosiglitazone
1750:
1748:
1747:Rivoglitazone
1745:
1743:
1740:
1738:
1735:
1733:
1727:
1725:
1722:
1720:
1717:
1715:
1712:
1710:
1707:
1705:
1702:
1700:
1699:Netoglitazone
1697:
1695:
1692:
1690:
1687:
1685:
1682:
1680:
1679:Lobeglitazone
1677:
1675:
1672:
1670:
1667:
1665:
1662:
1660:
1657:
1655:
1652:
1650:
1647:
1645:
1642:
1640:
1637:
1635:
1632:
1630:
1627:
1625:
1622:
1620:
1617:
1615:
1612:
1610:
1607:
1605:
1602:
1600:
1597:
1595:
1592:
1590:
1587:
1585:
1582:
1580:
1577:
1575:
1572:
1570:
1567:
1565:
1564:Balaglitazone
1562:
1560:
1557:
1555:
1552:
1550:
1547:
1545:
1542:
1540:
1534:
1532:
1529:
1527:
1524:
1521:
1520:
1518:
1513:
1507:
1501:
1498:
1496:
1493:
1491:
1488:
1485:
1484:
1481:
1478:
1476:
1475:Sodelglitazar
1473:
1471:
1468:
1466:
1463:
1461:
1458:
1456:
1453:
1451:
1448:
1446:
1443:
1441:
1438:
1436:
1433:
1431:
1428:
1426:
1423:
1421:
1418:
1416:
1413:
1411:
1408:
1406:
1403:
1400:
1399:
1397:
1392:
1386:
1380:
1377:
1375:
1372:
1369:
1368:
1365:
1362:
1360:
1357:
1355:
1352:
1350:
1347:
1345:
1344:Sodelglitazar
1342:
1340:
1337:
1335:
1332:
1330:
1327:
1325:
1322:
1320:
1317:
1315:
1312:
1310:
1307:
1305:
1302:
1300:
1299:Lobeglitazone
1297:
1295:
1292:
1290:
1287:
1285:
1281:Leukotriene B
1279:
1277:
1274:
1272:
1269:
1267:
1264:
1262:
1259:
1257:
1254:
1252:
1249:
1247:
1244:
1241:
1237:
1234:
1232:
1229:
1227:
1224:
1222:
1219:
1217:
1214:
1212:
1209:
1207:
1204:
1202:
1199:
1197:
1194:
1192:
1189:
1187:
1184:
1181:
1180:
1178:
1173:
1167:
1163:
1157:
1148:
1143:
1141:
1136:
1134:
1129:
1128:
1125:
1115:
1111:
1107:
1103:
1099:
1095:
1092:(7): 314ā21.
1091:
1087:
1086:
1077:
1074:
1069:
1065:
1061:
1057:
1053:
1049:
1045:
1041:
1040:
1031:
1028:
1023:
1019:
1014:
1009:
1004:
999:
995:
991:
990:
985:
978:
975:
970:
966:
962:
958:
954:
950:
946:
942:
941:
932:
930:
926:
921:
917:
913:
909:
906:(1): 90ā106.
905:
901:
900:
891:
888:
883:
879:
874:
869:
865:
861:
857:
853:
852:
847:
840:
837:
832:
828:
824:
820:
816:
812:
811:
802:
799:
794:
790:
785:
780:
776:
772:
768:
764:
763:
758:
751:
749:
745:
740:
736:
731:
726:
722:
718:
714:
710:
709:
704:
696:
694:
690:
685:
681:
676:
671:
667:
663:
659:
652:
649:
644:
640:
636:
632:
628:
624:
616:
613:
608:
604:
600:
596:
592:
588:
585:(7): 314ā21.
584:
580:
572:
569:
564:
560:
556:
552:
548:
544:
540:
536:
528:
525:
513:
507:
504:
498:
494:
491:
489:
486:
484:
481:
480:
476:
474:
467:
465:
455:
450:
448:
446:
438:
433:
431:
429:
425:
422:
418:
414:
410:
396:
391:
387:
380:
371:
367:
360:
353:
349:
348:
346:
343:
338:
331:
329:
325:
289:
287:
283:
278:
270:
266:
265:DTXSID9040760
262:
261:
259:
250:
246:
239:
235:
234:
232:
230:
226:
219:
215:
214:
212:
210:
206:
199:
195:
194:
192:
190:
186:
179:
175:
174:
172:
170:
166:
159:
155:
154:
152:
150:
146:
139:
135:
134:
132:
125:
121:
114:
110:
109:
107:
105:
101:
92:
88:
81:
76:
69:
68:
66:
64:
60:
55:
48:
47:
45:
43:
39:
36:Clinical data
34:
30:
25:
1993:Fluoroarenes
1939:
1884:Clinofibrate
1879:Ciprofibrate
1875:
1856:
1832:Antagonists:
1831:
1793:
1787:Troglitazone
1782:Tesaglitazar
1767:Sipoglitazar
1762:Saroglitazar
1737:Ragaglitazar
1724:Pioglitazone
1714:Pemaglitazar
1709:Peliglitazar
1694:Naveglitazar
1659:Lanifibranor
1654:Indeglitazar
1609:Edaglitazone
1604:Darglitazone
1584:Cevoglitazar
1522:
1487:Antagonists:
1486:
1460:Lanifibranor
1401:
1371:Antagonists:
1370:
1359:Troglitazone
1349:Tesaglitazar
1339:Saroglitazar
1334:Pioglitazone
1304:Muraglitazar
1276:Lanifibranor
1182:
1089:
1083:
1076:
1043:
1037:
1030:
993:
987:
977:
944:
938:
903:
897:
890:
855:
849:
839:
814:
808:
801:
766:
760:
712:
708:Biochemistry
706:
668:(1): 61ā71.
665:
661:
651:
626:
622:
615:
582:
578:
571:
541:(2): 240ā9.
538:
534:
527:
515:. Retrieved
506:
471:
459:
442:
434:Pharmacology
416:
412:
408:
407:
63:Legal status
57:Legal status
1914:Ronifibrate
1904:Farglitazar
1894:Englitazone
1777:Telmisartan
1704:Oxeglitazar
1649:Imiglitazar
1629:Farglitazar
1619:Englitazone
1614:Efatutazone
1594:Ciglitazone
1589:Chiglitazar
1579:Cannabidiol
1574:Bezafibrate
1554:Aleglitazar
1430:Elafibranor
1420:Bezafibrate
1319:Pemafibrate
1266:Gemfibrozil
1256:Fenofibrate
1246:Elafibranor
1216:Chiglitazar
1211:Bezafibrate
1196:Aleglitazar
996:: 5625ā32.
621:activity".
488:Elafibranor
456:Derivatives
335: gĀ·mol
238:ChEMBL38508
113:317318-84-6
78:Identifiers
1998:Thioethers
1957:Categories
1924:Simfibrate
1899:Etofibrate
1889:Clofibride
1742:Reglitazar
1470:Seladelpar
1435:Fonadelpar
1240:prasterone
1221:Clofibrate
1162:modulators
499:References
340:3D model (
328:Molar mass
198:4PZK9FJC4Z
169:ChemSpider
149:IUPHAR/BPS
104:CAS Number
87:IUPAC name
1988:Thiazoles
1876:Agonists:
1850:T-0070907
1674:LG-101506
1669:LG-100754
1664:LG-100268
1644:Ibuprofen
1634:Genistein
1569:Berberine
1526:5-Oxo-ETE
1523:Agonists:
1465:LG-101506
1455:L-165,041
1450:GW-501516
1440:Genistein
1402:Agonists:
1294:LG-100754
1289:LG-101506
1261:Genistein
1226:CP-775146
1183:Agonists:
817:: 18ā27.
451:Chemistry
1936:See also
1857:Unknown:
1624:Etalocib
1599:Daidzein
1549:15-HpETE
1500:GSK-3787
1495:GSK-0660
1425:Daidzein
1410:15-HpETE
1364:WY-14643
1251:Etomoxir
1231:Daidzein
1191:15-HpETE
1114:25631088
1106:18622687
1068:21168990
1060:20430778
1022:26508837
969:38565637
961:26147382
920:22521259
882:28825467
831:26686607
793:29287957
739:23713684
684:19351742
643:12699745
607:25631088
599:18622687
563:21295375
555:15211590
483:GW501516
477:See also
468:Research
417:fitorine
413:GW610742
42:ATC code
1860:SR-1664
1840:GW-9662
1820:MK-0533
1815:INT-131
1810:EPI-001
1796:SPPARMs
1639:GW-1929
1544:15-HETE
1445:GW-0742
1405:15-HETE
1374:GW-6471
1271:GW-7647
1186:15-HETE
1013:4610778
899:Surgery
873:5643073
784:6008168
730:3724348
424:agonist
421:PPARĪ“/Ī²
419:) is a
286:Formula
178:8110086
138:9934458
124:PubChem
1845:SR-202
1835:FH-535
1825:S26948
1757:RS5444
1689:nTZDpa
1490:FH-535
1379:MK-886
1112:
1104:
1066:
1058:
1020:
1010:
967:
959:
918:
880:
870:
829:
791:
781:
737:
727:
682:
641:
605:
597:
561:
553:
517:31 Mar
409:GW0742
366:SMILES
333:471.48
229:ChEMBL
218:C15625
21:GW0742
1805:BADGE
1511:PPARĪ³
1390:PPARĪ“
1171:PPARĪ±
1110:S2CID
1064:S2CID
965:S2CID
603:S2CID
559:S2CID
386:InChI
342:JSmol
1236:DHEA
1155:PPAR
1102:PMID
1056:PMID
1018:PMID
957:PMID
916:PMID
878:PMID
827:PMID
789:PMID
735:PMID
680:PMID
639:PMID
595:PMID
551:PMID
519:2013
415:and
209:KEGG
189:UNII
158:2686
49:None
1094:doi
1048:doi
1008:PMC
998:doi
949:doi
908:doi
904:152
868:PMC
860:doi
819:doi
815:122
779:PMC
771:doi
725:PMC
717:doi
670:doi
631:doi
587:doi
543:doi
445:VDR
254:EPA
128:CID
1959::
1108:.
1100:.
1090:57
1088:.
1062:.
1054:.
1044:88
1042:.
1016:.
1006:.
992:.
986:.
963:.
955:.
945:33
943:.
928:^
914:.
902:.
876:.
866:.
856:19
854:.
848:.
825:.
813:.
787:.
777:.
767:28
765:.
759:.
747:^
733:.
723:.
713:52
711:.
705:.
692:^
678:.
666:83
664:.
660:.
637:.
627:13
625:.
601:.
593:.
583:57
581:.
557:.
549:.
539:77
537:.
462:50
430:.
300:17
294:21
1802::
1731:2
1538:2
1283:4
1238:(
1146:e
1139:t
1132:v
1116:.
1096::
1070:.
1050::
1024:.
1000::
994:9
971:.
951::
922:.
910::
884:.
862::
833:.
821::
795:.
773::
741:.
719::
686:.
672::
645:.
633::
609:.
589::
565:.
545::
521:.
344:)
321:2
318:S
315:3
312:O
309:N
306:4
303:F
297:H
291:C
256:)
252:(
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