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Morgan DE, Spann JS, Lockhart ME, Winningham B, Bolus DN (April 2011). "Assessment of adverse reaction rates during gadoteridol-enhanced MR imaging in 28,078 patients".
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InChI=1S/C17H32N4O7.Gd/c1-14(22)10-18-2-4-19(11-15(23)24)6-8-21(13-17(27)28)9-7-20(5-3-18)12-16(25)26;/h14,22H,2-13H2,1H3,(H,23,24)(H,25,26)(H,27,28);/q;+3/p-3
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Specifically, the rate of nausea (0.530%) was less than half the rate (1.4%) in clinical trials of 1251 patients, leading to FDA approval in 1992.
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45:(10-(2-(hydroxy-κO)propyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3)-κN1,κN4,κN7,κN10,κO1,κO4,κO7)-gadolinium
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551:"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)"
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533:. Gadoteridol was first approved for use in the United States in 1992.
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609:"Gadoteridol (ProHance) prescribing information"
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461:.C(=O)CN1CCN(CCN(CCN(CC(O)C)CC1)CC()=O)CC()=O
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1007:
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607:Bracco Diagnostic Inc. (26 October 2022).
525:, used particularly in the imaging of the
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62:Micromedex Detailed Consumer Information
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523:gadolinium-based MRI contrast agent
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1319:. You can help Knowledge (XXG) by
1262:. You can help Knowledge (XXG) by
529:. It is sold under the brand name
396:
14:
1376:Nuclear magnetic resonance stubs
1303:
1246:
399:
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168:gadolinium(+3) cation; 2-acetate
27:
486:Key:DPNNNPAKRZOSMO-UHFFFAOYSA-K
580:"Prohance Product information"
405:
384:
1:
617:National Library of Medicine
1402:
1366:Organogadolinium compounds
1298:
1256:magnetic resonance imaging
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374:Chemical and physical data
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26:
1087:Ferric ammonium citrate
653:10.1148/radiol.10100906
1315:-related article is a
527:central nervous system
1381:Medical imaging stubs
1371:MRI contrast agents
1254:This article about
1191:Sulfur hexafluoride
23:
1386:Pharmacology stubs
1226:Never to phase III
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1327:
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1102:Superparamagnetic
1051:Gadopentetic acid
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440:Interactive image
343:CompTox Dashboard
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16:Chemical compound
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1184:Microspheres of
1021:Gadolinium-based
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927:Calcium iopodate
766:Ioxitalamic acid
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1216:Clinical trials
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1071:Gadoversetamide
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977:
942:Water insoluble
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931:
922:Tyropanoic acid
917:Sodium iopodate
902:Iobenzamic acid
892:Ioglycamic acid
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776:Acetrizoic acid
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498:(what is this?)
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1061:Gadoteric acid
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1038:
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1026:Gadobenic acid
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989:Barium sulfate
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588:. 30 July 1998
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913:
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907:Iopanoic acid
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903:
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890:
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887:Iotroxic acid
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800:Nephrotropic,
798:
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789:
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779:
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771:Ioglicic acid
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735:Nephrotropic,
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647:(1): 109–16.
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585:Health Canada
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332:ChEMBL1200593
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36:Clinical data
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25:
1321:expanding it
1313:pharmacology
1310:
1264:expanding it
1253:
1238:
1180:Perflenapent
1162:Microspheres
1092:Mangafodipir
1082:
1065:
1056:Gadopiclenol
1041:Gadofosveset
1019:
1012:Paramagnetic
968:Propyliodone
953:Ethyl esters
875:Hepatotropic
738:high osmolar
718:X-ray and CT
664:
644:
638:
632:
620:. Retrieved
612:
602:
590:. Retrieved
583:
574:
562:. Retrieved
554:
545:
530:
514:
513:
502:
496:
114:Legal status
108:Legal status
1212:from market
1066:Gadoteridol
1036:Gadodiamide
973:Iofendylate
959:, lipiodol)
957:fatty acids
955:of iodised
811:Metrizamide
803:low osmolar
515:Gadoteridol
423: g·mol
312:CHEBI:31643
187:120066-54-8
152:Identifiers
41:Other names
21:Gadoteridol
1360:Categories
1154:Ultrasound
1140:Perflubron
1120:Iron oxide
1115:Ferristene
1110:Ferumoxsil
1046:Gadolinium
1031:Gadobutrol
940:Iodinated,
897:Adipiodone
861:Iobitridol
726:Iodinated,
537:References
428:3D model (
416:Molar mass
272:0199MV609F
243:ChemSpider
178:CAS Number
161:IUPAC name
1222:Phase III
1210:Withdrawn
1175:galactose
851:Iodixanol
831:Iopromide
826:Iopamidol
786:Methiodal
640:Radiology
70:Routes of
56:Drugs.com
856:Iomeprol
846:Iopentol
841:Ioversol
836:Iotrolan
756:Iodamide
661:21248237
613:DailyMed
592:19 April
531:ProHance
505:(verify)
223:DrugBank
84:ATC code
963:Iopydol
866:Ioxilan
816:Iohexol
791:Diodone
615:. U.S.
521:) is a
380:Formula
232:DB00597
198:PubChem
144:Rx-only
141:WARNING
126::
100:)
94: (
92:V08CA04
1205:WHO-EM
659:
622:17 May
564:22 Oct
454:SMILES
421:558.69
323:ChEMBL
292:D01137
138:
128:℞-only
1311:This
1258:is a
1133:Other
1083:Other
474:InChI
430:JSmol
303:ChEBI
252:54719
212:60714
1317:stub
1260:stub
657:PMID
624:2023
594:2024
566:2023
283:KEGG
263:UNII
52:AHFS
1173:of
1164:of
1003:MRI
951:(=
709:V08
649:doi
645:259
559:FDA
519:INN
348:EPA
202:CID
97:WHO
1362::
1218::
1122:,
1085::
1024::
663:.
655:.
643:.
611:.
582:.
557:.
553:.
397:Gd
394:29
388:17
134:US
123:CA
77:IV
1348:e
1341:t
1334:v
1323:.
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1266:.
711:)
707:(
697:e
690:t
683:v
651::
626:.
596:.
568:.
517:(
432:)
409:7
406:O
403:4
400:N
391:H
385:C
350:)
346:(
136::
54:/
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
