41:
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459:
644:
Nair, Jayaprakash K; Willoughby, Jennifer L. S; Chan, Amy; Charisse, Klaus; Alam, Md. Rowshon; Wang, Qianfan; Hoekstra, Menno; Kandasamy, Pachamuthu; Kel'In, Alexander V; Milstein, Stuart; Taneja, Nate; o'Shea, Jonathan; Shaikh, Sarfraz; Zhang, Ligang; Van Der Sluis, Ronald J; Jung, Michael E; Akinc,
616:
Donald M. Marcus; Elvin A. Kabat; Gerald
Schiffman (1964). "Immunochemical Studies on Blood Groups. XXXI. Destruction of Blood Group A Activity by an Enzyme from Clostridium tertium Which Deacetylates N-Acetylgalactosamine in Intact Blood Group Substances".
645:
Akin; Hutabarat, Renta; Kuchimanchi, Satya; Fitzgerald, Kevin; Zimmermann, Tracy; Van Berkel, Theo J. C; Maier, Martin A; Rajeev, Kallanthottathil G; Manoharan, Muthiah (2014).
472:
135:
343:
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693:
647:"Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing"
479:
251:
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272:
40:
719:
317:
InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6+,7-,8+/m1/s1
327:
InChI=1/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6+,7-,8+/m1/s1
518:
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549:, and is concentrated in sensory nerve structures of both humans and animals.
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Except where otherwise noted, data are given for materials in their
215:
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In humans it is the terminal carbohydrate forming the antigen of
206:
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172 to 173 °C (342 to 343 °F; 445 to 446 K)
564:
therapies targeted to the liver, where it binds to the
524:
It is typically the first monosaccharide that connects
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110:
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77:-Acetylchondrosamine; 2-Acetamido-2-deoxy-
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651:Journal of the American Chemical Society
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348:
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194:
545:-Acetylgalactosamine is necessary for
320:Key: OVRNDRQMDRJTHS-CBQIKETKSA-N
154:
7:
552:GalNAc is also used as a targeting
330:Key: OVRNDRQMDRJTHS-CBQIKETKBW
230:
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25:
687:
457:
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532:in particular forms of protein
453:(at 25 °C , 100 kPa).
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372:
1:
566:asialoglycoprotein receptors
69:GalNAc; 2-Acetamido-2-deoxy-
547:intercellular communication
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558:antisense oligonucleotides
402:221.21 g/mol
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57:2-(Acetylamino)-2-deoxy-
351:O(C(CO)O(O)1NC(C)=O)1O
694:N-Acetylgalactosamine
34:-Acetylgalactosamine
696:at Wikimedia Commons
495:-Acetylgalactosamine
657:(49): 16958–16961.
631:10.1021/bi00891a023
556:in investigational
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596:-Acetylglucosamine
480:Infobox references
434:-Acetylglucosamine
417:Related compounds
81:-galactopyranose;
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692:Media related to
663:10.1021/ja505986a
488:Chemical compound
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273:CompTox Dashboard
136:Interactive image
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27:Chemical compound
16:(Redirected from
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89:-galactosamine
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582:Galactosamine
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95:Identifiers
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73:-galactose;
67:Other names
31:
715:Hexosamines
570:hepatocytes
519:blood group
503:amino sugar
360:Properties
156:CHEBI:40356
710:Acetamides
704:Categories
603:References
501:), is an
398:Molar mass
261:833755V695
167:ChemSpider
123:3D model (
102:CAS Number
61:-galactose
54:IUPAC name
587:Globoside
530:threonine
507:galactose
442:Galactose
112:1811-31-0
671:25434769
598:) GlcNAc
576:See also
513:Function
423:Related
187:DrugBank
85:-Acetyl-
473:what is
471: (
228:PubChem
196:DB03567
669:
554:ligand
526:serine
499:GalNAc
468:verify
465:
344:SMILES
216:C01074
48:Names
18:GalNAc
562:siRNA
309:InChI
241:84265
176:76020
147:ChEBI
125:JSmol
667:PMID
560:and
252:UNII
207:KEGG
659:doi
655:136
627:doi
572:.
568:on
528:or
521:A.
278:EPA
231:CID
706::
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509:.
382:15
673:.
661::
633:.
629::
623:3
594:N
591:(
543:N
535:O
497:(
493:N
463:N
432:N
391:6
388:O
385:N
379:H
376:8
373:C
280:)
276:(
127:)
87:D
83:N
79:D
75:N
71:D
59:D
32:N
20:)
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