Gilead Sciences - Knowledge (XXG)

645: 5947: 654: 40: 49: 1097: 2066:. In the US, for instance, it was launched at $ 1,000 per pill or $ 84,000 for the standard 84-day course, but it was drastically cheaper in the developing world; in India, it dropped as low as $ 4.29 per pill. While Sovaldi represented a significant improvement over contemporary treatments, the controversy surrounding its price ignited a national debate in the US, according to Reuters. 455: 435: 415: 395: 372: 2184:, the sale of assets between affiliated entities. In particular, Gilead sells intellectual property to an Irish subsidiary, which then sells the finished products, such as Sovaldi, in the United States and elsewhere, paying the low Irish tax rate on profits. The practice is common among multinational pharmaceutical companies like Gilead. 777:. According to Riordan, he had always wanted to use the name Gilead Sciences all along. Still, he used Oligogen as a temporary name because he needed to deal with a trademark clearance issue with a California nonprofit organization that was already using the word Gilead in its name. He had first heard of the 2157:

developed countries where the cheaper, generic alternatives were still unavailable. (In India, a one-month treatment cost approximately US$ 300, versus $ 1,000 per pill in the United States.) Gilead required the Indian producers to screen patients to determine who could buy Sovaldi, which was criticized by

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Gilead introduced Truvada for PreP in 2012, at which point a prescription cost approximately $ 1,200 per month in the United States. By 2018, this price had increased to up to $ 2,000, despite generally costing less than $ 100 outside the U.S. Gilead made over $ 3 billion in sales of Truvada in 2018.

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launched an 18-month investigation of Gilead's Sovaldi pricing, and argued in its 2015 report that Gilead set prices high in disregard of the human cost and in order to set the stage for a higher eventual price for Sovaldi's successor, Harvoni. The committee's investigation, based in part on internal

1590:. This treatment for hepatitis C cures the patient in 94% to 99% of cases (HCV genotype 1). By 2017, Gilead was reporting drastic drops in Sovaldi revenue from year to year, not only because of pricing pressure but because the number of suitable patients decreased. Later single-pill combinations were 1251:

On May 9, 2019, the U.S. Department of Health and Human Services announced that Gilead Sciences will donate Truvada, the only drug approved to prevent infection with H.I.V., for free to 200,000 patients annually for 11 years. On December 3, 2019, HHS explained how the government would distribute the

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In October 2011, Gilead broke ground on a massive multi-year expansion of its 17-building headquarters campus in Foster City. By replacing eight one or two-story buildings with seven new structures ranging as tall as 10 stories, Gilead nearly doubled its headquarters real estate footprint from about

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In 2009, the company acquired CV Therapeutics, Inc. for $ 1.4 billion, bringing Ranexa and Lexiscan into Gilead. Ranexa is a cardiovascular drug used to treat chest pain related to coronary artery disease, with both of these products and pipeline building out Gilead's cardiovascular franchise. Later

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in the ACA; Leerink analyst Geoffrey Porges wrote that Gilead's HIV drugs could face funding pressure under reform proposals. Gilead has $ 32 billion in cash, but $ 27.4 billion is outside the U.S. and is unavailable for acquisitions unless Gilead pays U.S. tax on it, though it could borrow against

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Later in the same year, Gilead acquired Myogen, Inc. for $ 2.5 billion (then its largest acquisition). With two drugs in development (ambrisentan and darusentan), and one marketed product (Flolan) for pulmonary diseases, the acquisition of Myogen has solidified Gilead's position in this therapeutic

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In 2010, the company acquired CGI Pharmaceuticals for $ 120 million, expanding Gilead's research expertise into kinase biology and chemistry. Later that year, the company acquired Arresto Biosciences, Inc. for $ 225 million, obtaining developmental-stage research for treating fibrotic diseases and

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noted that by 2003, the Gilead corporate campus in Foster City had expanded to "seven low-slung sand-colored buildings around a tiny lake on which ducks happily paddle." Like many startups, Gilead originally leased its space, but in 2004, the company paid $ 123 million to buy all its headquarters

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Riordan later recalled that Gilead's first decade as a startup was an extremely stressful experience for him, as a young venture capitalist serving for the first time as the founder, chairman, and chief executive officer of his own biotech company. The new company had no products and very little

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Emergency use authorization for remdesivir was granted in the U.S. on May 1, 2020, for people hospitalized with severe COVID-19. In September 2020 following a review of the evidence, the WHO issued guidance not to use remdesivir for people with COVID-19, as there was no good evidence of benefit.

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and was the subject of a Congressional hearing in May 2019. Gilead's CEO defended its pricing in the hearing by noting the large sums the company spends on HIV/AIDS research. Activists pressured the US government to enforce its patent on Truvada in order to combat the high prices set by Gilead.

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asking Gilead to justify the price for this drug. The committee hearings did not result in new law, but in 2014 and 2015, due to negotiated and mandated discounts, Sovaldi was sold well below the list price. For poorer countries, Gilead licensed multiple companies to produce generic versions of

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One reason for entering into the Tamiflu licensing agreement was that with only 350 employees, Gilead still did not yet have the capability to sell its drugs directly to overseas buyers. To avoid having to license future drugs in order to access international markets, Gilead simply acquired the

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in profits through an Irish entity in just two years" without paying Irish taxes. The company repatriated a portion of the Irish subsidiary's holdings, $ 28 billion, to the United States in 2018 following reductions of the corporate tax rate. For this it paid an estimated $ 5.5 billion in tax.

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For the fiscal year 2017, Gilead Sciences reported earnings of US$ 4.628 billion and annual revenue of US$ 26.107 billion, a decline of 14.1% over the previous fiscal cycle. Gilead Sciences's shares traded at over $ 70 per share, and its market capitalization was valued at US$ 93.4 billion in

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sold shares of the company, receiving more than $ 5 million in capital gains, while still maintaining up to $ 25m-worth of shares by the end of the year. Sales of Tamiflu almost quadrupled again in 2005, to $ 161.6m, during which time the share price tripled. A 2005 report showed that, in all,

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In response to criticisms over the price of Sovaldi, Gilead began licensing the rights to produce generic versions of the drug to select producers in India in 2015. Included in the licensing agreements were 'anti-diversion' provisions, designed to prevent the drug from being exported back to

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noted that the donations still covered less than one-fifth of the people who need the drug, and argued it was possibly a move to help the company market Descovy, a more advanced successor drug. Walensky led a 2020 study that concluded the high costs of Descovy would on the whole negate any

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pandemic scare, Gilead Sciences' revenue from Tamiflu almost quadrupled to $ 44.6m as more than 60 national governments stockpiled the antiviral drug, though the firm had made a loss in 2003 before concern about the flu started. As stocks soared, US Defense Secretary and Pentagon chief

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documents obtained from Gilead, revealed that the company had considered prices ranging from $ 50,000 to $ 115,000 per year, trying to strike a balance between revenue and predicted activist and public relations blowback, with little regard to research and development costs.

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Gilead has also been accused of stifling competition. A lawsuit filed in the United States in 2019 alleged that the company entered "pay for delay" agreements with other manufacturers, wherein the manufacturers agreed to delay releasing generic versions of Truvada. In 2021,

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The company continued its growth in the 2010s. However, it came under heavy scrutiny over its business practices, including extremely high pricing of drugs such as Sovaldi and Truvada in the United States relative to production cost and cost in the developing world.

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Public outrage over the cost of Sovaldi in 2013 - despite that it was a vast improvement over existing equally expensive therapies - ignited a national debate on fair pricing for prescription medicines that the pharmaceutical industry has fought to deflect ever

2222:(FDA) on March 23, 2020. This designation is intended to encourage the development of drugs affecting fewer than 200,000 Americans by granting strengthened and extended legal monopoly rights to the manufacturer, along with waivers on taxes and government fees. 799:

species from that part of that world, and was therefore inspired to name his company Gilead. After founding Oligogen, he contacted the nonprofit about the naming issue and secured the right to use the Gilead Sciences name in exchange for a $ 1,000 donation.

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In January 2022, Gilead pulled its cancer drug Zydelig (idelalisib) from its accelerated approval in relapsed follicular B-cell non-Hodgkin lymphoma (FL) and relapsed small lymphocytic leukemia (SLL). In September, the company completed its acquisition of

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for use in adults and children (12 years of age and older who weigh at least 40 kilograms (88 lb) and are positive for COVID-19, not hospitalized, and are ill having high risk for developing severe COVID-19, including hospitalization or death.

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buildings from its landlords. However, even as Gilead developed its ability to distribute and sell its own drugs, it remained distinct from most pharmaceutical companies in terms of its strong reliance on subcontracting most of its manufacturing to

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By 1988, the company had moved its headquarters to Foster City's Vintage Park neighborhood, where it has been based ever since. The company began to develop small molecule antiviral therapeutics in 1991, when the company in-licensed a group of

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Gilead's first TAF medication, marketed under the trade name Genvoya, came out in 2015. Lawsuits allege that in the interim period, many HIV patients who continuously took Gilead's older TDF-based drugs suffered severe side effects, including

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had made a preliminary approach to Gilead for a potential merger, worth almost $ 240 billion. In the same month, the company announced it would acquire a 49.9% stake in privately held Pionyr Immunotherapeutics Inc for $ 275 million.

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for $ 95.50 a share ($ 4.9 billion in total). On April 7, 2020, Gilead completed acquisition of Forty Seven, Inc. for "$ 95.50 per share, net to the seller in cash, without interest, or approximately $ 4.9 billion in the aggregate."

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income, and narrowly escaped going out of business on several occasions: "It was touch and go for a long time". Finding a way for Gilead to make money was Riordan's top priority "every second of the day for eight years".

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Truvada was introduced to the market by Gilead in 2004 to treat HIV infections. In the following years, the United States government conducted research demonstrating that Truvada was able to prevent HIV infection. The US

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reported that in-hospital people with COVID-19 treated with remdesivir had lower death rates (by about 4%) and reduced need for oxygen and mechanical ventilation compared to people receiving standard-of-care treatments.

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In 2006, the company acquired Corus Pharma, Inc. for $ 365 million. The acquisition of Corus signaled Gilead's entry into the respiratory arena. Corus was developing aztreonam lysine for the treatment of patients with

2029:. Plaintiffs allege that Gilead suspended TAF in 2004 despite clear evidence indicating that TAF-based medications were safer than TDF, a compound whose long-term use was associated with adverse side effects such as 2114:

In May 2019, Gilead announced it would donate enough Truvada to treat up to 200,000 patients annually for up to 11 years, the result of discussions with the Department of Health and Human Services under Trump. Dr.

3140:"U.S. Food and Drug Administration (FDA) Approves Atripla (efavirenz 600 mg/ emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen For Adults With HIV-1 Infection" 4925: 1549:

investigated Sovaldi's high price ($ 1,000 per pill; $ 84,000 for the full 12-week regimen). Senators questioned the extent to which the market was operating "efficiently and rationally", and committee chairman

2249:, remdesivir had been approved for treatment of hospitalized people with COVID-19 in the United States, European Union, and multiple other countries. In 2022, the Canadian component of the WHO international 1119:($ 225 million plus milestone payments). The acquisition boosted Gilead's oncology and inflammation areas. Later that year, Gilead made its most important acquisition – and by then most expensive – with the 3597: 2127:

reimbursements to clinics serving primarily low-income communities; clinics argued this severely hinders their ability to provide HIV/AIDS prevention and treatment services among vulnerable populations.

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programs to ration treatment to patients, delaying treatment of less advanced hepatitis C cases. In Oregon, for example, 10,000 Medicaid patients were deemed good candidates for Sovaldi therapy, but the

2177:, is the use of legal means to shift tax burdens from the one jurisdiction to overseas affiliates that pay a lower tax rate, even if revenue is primarily generated outside the overseas jurisdiction. 618:, among others. It began evolving from a biotechnology company into a pharmaceutical company, acquiring several subsidiaries, though it still relied heavily on contracting to manufacture its drugs. 2862: 2285:

treatment of children under age 12 who are COVID-positive and not hospitalized, but have mild-to-moderate COVID-19 with high risk of developing severe COVID-19, including hospitalization or death.

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antibody-drug conjugate. In December, the business announced it would acquire German biotech, MYR GmbH, for €1.15 billion plus up to a further €300 million. MYR focuses on the treatment of chronic

5202:"Comparative Pricing of Branded Tenofovir Alafenamide–Emtricitabine Relative to Generic Tenofovir Disoproxil Fumarate–Emtricitabine for HIV Preexposure Prophylaxis: A Cost-Effectiveness Analysis" 2583: 1988:

As of 2017, Gilead's challenge is to develop or acquire new blockbuster drugs before its current revenue-producers wane or their patent protection expires. Gilead benefited from the expansion of

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In 2016, the company acquired Nimbus Apollo, Inc. for $ 400 million, giving Gilead control of the compound NDI-010976 (an ACC inhibitor) and other preclinical ACC inhibitors for the treatment of

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since it could lead to the exclusion of vulnerable groups like refugees and migrants from accessing the medicines. In response to the criticism, Gilead eventually relaxed these requirements.

4988: 4402: 1161:(JAK) family, specifically JAK1 and JAK2, into Gilead's oncology pipeline. The JAK enzymes have been implicated in myeloproliferative diseases, inflammatory disorders, and certain cancers. 4198: 2353: 3896: 7378: 5018: 3429: 3344: 1039:, a German company. Raylo Chemical was a custom manufacturer of active pharmaceutical ingredients and advanced intermediates for the pharmaceutical and biopharmaceutical industries. 6005: 5982: 4251: 2269:(FDA) in October 2020 use in hospitalized adults and children 12 years and older for treatment of severe COVID-19 infections. In January 2022, the FDA gave regulatory approval to 7383: 7363: 7358: 3370: 1256:

explained that the U.S. government will pay Gilead $ 200 per bottle for 30 pills for costs associated with getting the drug from factories into the eventual hands of patients.

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Remdesivir became a candidate for treating COVID-19; at the time the status was granted, fewer than 200,000 Americans had COVID-19, but numbers were climbing rapidly as the

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A 2016 report by the liberal think tank Americans for Tax Fairness argued that Gilead was able to avoid up to $ 10 billion in taxes on U.S. sales through mechanisms such as

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estimated that treating half of these patients would more than double the state's total drug expenditures. The state thus opted to limit treatment to 500 patients per year.

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magazine ranked Gilead its number 4 drug company, citing a market capitalization of US$ 113 billion and stock appreciation of 100%, and describing their 2011 purchase of

4936: 3485: 5250: 5042: 1248:. In November, the company announced it will acquire Cell Design Labs for up to $ 567 million, after it indirectly acquired a stake of 12.2% via the Kite Pharma deal. 935:

that was near FDA approval, and it had two other antivirals in its pipeline. The company also announced its first full year of profitability. Later that year, Hepsera (

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Abate, Tom (August 23, 1999). "Gilead's Success, Pipeline Has Been a Balm for Biotech Investors – Foster City firm's shares have jumped 250% in past year".

4699:"Interim Results of a Phase 1b/2 Study of Entospletinib (GS-9973) Monotherapy and in Combination with Chemotherapy in Patients with Acute Myeloid Leukemia" 4337: 5388: 7343: 6487: 6477: 6467: 6457: 6447: 6437: 6427: 6417: 6407: 3872: 3627: 5657:

Rizk, John G.; Forthal, Donald N.; Kalantar-Zadeh, Kamyar; Mehra, Mandeep R.; Lavie, Carl J.; Rizk, Youssef; Pfeiffer, JoAnn P.; Lewin, John C. (2021).

1059:. Additionally, Myogen was developing (in Phase 3 studies) darusentan, also an endothelin receptor antagonist, for the potential treatment of resistant 5606: 3139: 2415: 2021:

Several mass tort lawsuits have been filed against Gilead alleging that the company deliberately delayed development of antiretroviral drugs based on

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In December 2002, Gilead and Triangle Pharmaceuticals announced that Gilead would acquire Triangle for around $ 464 million; Triangle's lead drug was

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It paid $ 425 million for a 15% equity stake in Galapagos NV, with additional payments for Gilead to license the experimental anti-inflammatory drug

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reached the US, and crossing the threshold soon was considered inevitable. Gilead retains 20-year remdesivir patents in more than 70 countries.

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had been part of the 2011 acquisition of Pharmasset. In 2013, the FDA approved this drug, under the trade name Sovaldi, as a treatment for the

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for $ 11.9 billion, equating to $ 180 cash per share, a 29% premium over the closing price of the shares. The deal was Gilead's entry into the

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completed its acquisition of Tmunity Therapeutics In May, the business announced it would acquire XinThera and its small molecule inhibitors.

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to avoid U.S. corporate taxes on global profits, stating that the firm "used a controversial tax loophole arrangement to shift almost

863: 696: 676: 387: 5512: 4577: 3345:"Gilead Sciences to Acquire Calistoga Pharmaceuticals for $ 375 Million; Deal Adds Pipeline Candidates in Oncology and Inflammation" 2779: 2740: 5773: 4641: 4223: 2324: 975:

In 2006, Gilead completed two acquisitions that allowed the company to branch out from its historical antiviral franchise into the

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noted the FDA approval and subsequent strong sales of the "potentially revolutionary" drug as a positive indicator for the stock.

6752: 1319: 715:, along with H. Dubose Montgomery, one of Menlo Ventures founders. Riordan served as CEO from the company's founding until 1996. 680: 2803: 7373: 3400: 734:

The company's primary therapeutic focus was in antiviral medicines, a field that piqued Riordan's interest after he contracted

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Lamontagne F, Agoritsas T, Macdonald H, Leo YS, et al. (September 2020). "A living WHO guideline on drugs for covid-19".

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Gilead expanded its move into respiratory therapeutics in 2007 by entering into a licensing agreement with Parion for an

6378: 5536: 4237: 2888: 2584:"Gilead Sciences Board Resolution Michael Riordan Founder CEO Chairman Antiviral Medicine AIDS Therapeutics Nucleotides" 2266: 2219: 1575: 1001: 662: 3319:"Gilead Sciences to Acquire Arresto Biosciences for $ 225 Million; Deal Adds Pipeline Candidates for Fibrotic Diseases" 719:

subsequently made the first investment in Gilead of $ 2 million. Riordan also recruited scientific advisers, including

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It bought EpiTherapeutics for $ 65 million. This acquisition gave Gilead first-in-class small molecule inhibitors of

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it. Gilead would benefit from proposals to let companies repatriate offshore capital with minimal further taxation.

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Gilead later combined Sovaldi with other antivirals in single-pill combinations. First, Sovaldi was combined with

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During this era, Gilead completed its gradual evolution from a biotech startup into a pharmaceutical company. The

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In 2002, Gilead changed its corporate strategy to focus exclusively on antivirals, and sold its cancer assets to

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for prevention of HIV infection (it was already approved for treating HIV). The pill was a preventive measure (

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Gilead was founded in 1987 under the name Oligogen by Michael L. Riordan. The original name was a reference to

6690: 4873:"Gilead Lawsuits: 41 HIV and PrEP Patients File California Personal Injury Case Over Gilead's TDF-Based Drugs" 4036: 3318: 3208: 905:. Tamiflu was originally discovered by Gilead and licensed to Roche for late-phase development and marketing. 5841:"Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial" 5200:

Walensky, Rochelle P.; Horn, Tim; McCann, Nicole C.; Freedberg, Kenneth A.; Paltiel, A. David (May 5, 2020).

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In 2013, the company acquired YM Biosciences, Inc. for $ 510 million. The acquisition brings drug candidate

833: 684: 644: 596: 545: 200: 166: 5587: 4185:"Dow Jones Sustainability Indices Results Announced: Alphabet, Medtronic are in, Nestlé, TotalEnergies Out" 2836: 7287: 7282: 7172: 7142: 7102: 6922: 6912: 6645: 6615: 6565: 6520: 6368: 6059: 5424: 2626: 1341: 993: 5149: 4552: 3801: 3765: 3187: 6720: 6525: 6343: 6308: 6154: 6134: 5753: 2022: 1587: 1567: 1555: 1301: 1293: 825: 743: 573: 3749: 3645: 691:, where Michael was an associate. Three scientific advisers worked with Riordan to create the company: 1265: 909:

480-employee NeXstar, which had already built its own sales force in Europe to market AmBisome there.

7252: 7122: 6952: 6680: 6655: 6605: 6600: 6580: 6530: 6463: 6453: 6323: 6298: 6206: 6201: 6169: 6099: 6069: 5478: 4932: 4199:"Gilead Statement on Zydelig® U.S. Indication for Follicular Lymphoma and Small Lymphocytic Leukemia" 3209:"Parion Sciences and Gilead Sciences Sign Agreement to Advance Drug Candidates for Pulmonary Disease" 3113: 2150: 2146: 2026: 1225:. Charitable donations to HIV/AIDS and liver disease organizations totaled over 440 million in 2015. 1169: 1021: 1013: 376: 4252:"Gilead Strengthens Early Pipeline in Oncology and Inflammation Through the Acquisition of XinThera" 7097: 6771: 6705: 6670: 6660: 6585: 6570: 6293: 6288: 6029: 6019: 5393: 5389:"The drug company that shocked the world with its prices dodged $ 10 billion in taxes, report says" 4698: 4154: 1052: 925: 708: 5333: 2236:) generated more than $ 4.5 billion in annual revenues, and was Gilead's highest selling product. 1376: 7227: 7192: 7167: 7107: 7067: 7047: 6992: 6630: 6443: 6413: 6363: 6129: 6114: 5741: 4451: 4357: 4150:"Rand Paul discloses 16 months late that his wife bought stock in company behind covid treatment" 3806: 3770: 3270: 3242: 3087: 2651: 1469: 1195: 1084: 704: 5974: 2558: 1199: 5277:"Gilead is accused of cutting anti-competitive deals to extend profit on HIV drug combinations" 4130: 7267: 7127: 6862: 6610: 6575: 6064: 5870: 5733: 5696: 5678: 5398: 5231: 4854: 4813: 4443: 4362: 4159: 4063: 3811: 3775: 3460:"Drug Approval Package: Truvada (Emtricitabine and Tenofovir Disoproxil Fumarate) NDA #021752" 2970: 2952: 2811: 2775: 2736: 2519: 2513: 2246: 2226: 2116: 1519: 1128: 1032: 890: 874: 770: 700: 541: 5914:"FDA Takes Actions to Expand Use of Treatment for Outpatients with Mild-to-Moderate COVID-19" 3237: 2769: 2730: 1327: 7277: 7152: 7072: 6902: 6832: 6338: 6276: 6256: 6211: 6196: 6139: 5860: 5852: 5795: 5723: 5686: 5670: 5221: 5213: 4872: 4844: 4803: 4795: 4710: 4435: 3538: 3188:"ClinicalTrials.gov – Information on Clinical Trials and Human Research Studies: Darusentan" 2960: 2250: 2181: 1344:,and in September, paid Genesis Therapeutics $ 35 million for AI-based drug discovery work. 751: 720: 511: 447: 193: 4831:

Grigsby, Iwen F.; Pham, Lan; Mansky, Louis M.; Gopalakrishnan, Raj; Mansky, Kim C. (2010).

2543: 7077: 7037: 7007: 6977: 6685: 6595: 6590: 6231: 6179: 3082: 1172:(FXR) program used small-molecule FXR agonists in the treatment of liver diseases such as 1044: 988: 968: 963: 859: 844: 766: 739: 728: 592: 5124:"Gilead CEO insists federal government patent for HIV prevention pill Truvada is invalid" 4585: 2704:

Jacobs, Paul (April 5, 2004). "Gilead Gets Well – Tough Medicine Works At Biotech Firm".

5043:"How an $ 84,000 drug got its price: 'Let's hold our position … whatever the headlines'" 4426:

Keating GM (2015). "Ledipasvir/Sofosbuvir: a review of its use in chronic hepatitis C".

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Rumsfeld owned shares worth up to $ 95.9m, from which he got an income of up to $ 13m.

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while in medical school, then learned that naturally occurring acetylsalicylic acid (

127: 122: 83: 70: 17: 6763: 4715: 4455: 39: 7147: 7087: 6962: 6892: 6872: 6867: 6473: 5251:"Pharma giant's policy change will devastate local HIV-prevention clinics' efforts" 4900:"Patients sue Gilead, saying drug company intentionally delayed safer HIV medicine" 4758:"Patients sue Gilead, saying drug company intentionally delayed safer HIV medicine" 2677: 2138: 2034: 1607: 1477: 1285: 1233: 1158: 1060: 878: 774: 747: 735: 692: 5359: 3512:"FDA approves first drug for reducing the risk of sexually acquired HIV infection" 48: 5674: 4784:"Tenofovir Effect on the Kidneys of HIV-Infected Patients: A Double-Edged Sword?" 4103:"Gilead Moves Deeper into Oncology with $ 21 Billion Acquisition of Immunomedics" 3954:"A new pharma king? AstraZeneca approaches Gilead about potential merger: report" 2354:"Activists pounce on $ 1,000-a-day price for Gilead's hep C wonder drug, Sovaldi" 862:

was appointed chairman, but left the board in January 2001 when he was appointed

7297: 7262: 7257: 7232: 7082: 6997: 6972: 6877: 6665: 6348: 6216: 5360:"How big pharma and the Indian government are letting millions of patients down" 5303:"Pharmacy chains sue Gilead for allegedly blocking lower-cost generic HIV drugs" 2211: 2174: 2063: 1603: 1595: 1447: 1334: 1312: 1277: 1229: 1219: 1180: 1096: 980: 940: 898: 561: 557: 5563:"FDA Grants Experimental Coronavirus Drug Benefits For Rare Disease Treatments" 4926:"Gilead's HCV drug sofosbuvir approved by the FDA but accessible for how many?" 1536:

estimated Sovaldi sales in the year's final quarter would be $ 53 million, and

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Gilead came under intense criticism for its high pricing of its patented drug

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inhibitor for the treatment of pulmonary diseases, including cystic fibrosis,

1036: 805: 585: 581: 577: 407: 105: 99: 93: 5682: 5402: 4732:""Morally Blameworthy" Gilead Under Fire in Legal Battle Over HIV Medication" 4366: 4163: 4067: 3815: 3779: 3689:"Growth-hungry Gilead finally pivots from flagging hep C with $ 12B Kite buy" 3401:"Gilead breaking ground on 1st part of massive campus rebuild in Foster City" 2956: 2815: 2099:

holds the patent for this use of Truvada as pre-exposure prophylaxis (PreP).

2025:

in order to maximize profits from previous-generation medications containing

7237: 7207: 7132: 7092: 7042: 6942: 6882: 6675: 6545: 6318: 6283: 6144: 6119: 5956: 5633:"Resurgent Veklury delivers Gilead $ 1.9B in sales and an earnings surprise" 5517: 5425:"Gilead avoided nearly $ 10 billion in taxes last year thanks to tax dodges" 2189: 2120:

comparative advantage of prescribing it over a generic Truvada alternative.

1551: 1308: 1253: 1214:. Also in 2016, the company was named the most generous company on the 2016 1009: 918: 902: 848: 840: 809: 565: 5874: 5737: 5700: 5235: 4989:"Will Gilead price its coronavirus drug for public good or company profit?" 4858: 4817: 4799: 4447: 3873:"Gilead buys Forty Seven for $ 4.9 billion to bolster cancer drug pipeline" 2974: 2387: 1288:

for $ 21 billion ($ 88 per share), gaining control of the cancer treatment

2939:

Masho, Saba Woldemichael; Wang, Cun-Lin; Nixon, Daniel E (December 2007).

7247: 7217: 7022: 7017: 7002: 6907: 6887: 6555: 6550: 6433: 6423: 6094: 5072:"#BreakThePatent: How HIV activists are going after Gilead's PrEP patent" 3837:"Gilead to Acquire Immuno-Oncology Company Forty Seven for $ 4.9 Billion" 3165: 2926: 2711: 2078: 1989: 1289: 1245: 1241: 1082:

that year, the company was named one of the Fastest Growing Companies by

936: 882: 762: 595:, small strands of DNA used to target genetic sequences. Gilead held its 569: 553: 352: 312: 287: 282: 242: 237: 227: 5856: 4131:"Gilead to acquire German biotech firm MYR for about 1.15 billion euros" 3671:"Gilead to buy Kite for promising cancer therapies in $ 12 billion deal" 3371:"Gilead Sciences to Acquire Calistoga Pharmaceuticals for $ 375 Million" 3142:(Press release). Bristol-Myers Squibb and Gilead Sciences. July 12, 2006 1027:

Gilead purchased Raylo Chemicals, Inc. in November 2006, for a price of

7302: 7212: 7197: 7137: 6982: 6947: 6710: 6560: 6483: 6403: 6373: 6271: 6236: 6174: 6089: 6049: 6034: 5966: 5607:"Gilead lifts 2021 guidance as remdesivir sales more than double in Q3" 2142: 1591: 1143: 1005: 894: 792: 761:

The company focused its early research on making small strands of DNA (

615: 604: 600: 357: 337: 332: 322: 317: 307: 297: 292: 277: 272: 267: 262: 257: 252: 247: 232: 5728: 4037:"Gilead to buy 49.9% stake in cancer drug developer for $ 275 million" 3628:"Gilead Sciences: Nimbus Drug Acquired, Offering Cure For Fatty Liver" 7202: 7187: 7182: 7162: 7062: 7012: 6987: 6967: 6957: 6927: 6897: 6822: 6715: 6650: 6640: 6535: 6266: 6079: 6024: 5217: 4963:"The same pill that costs $ 1,000 in the U.S. sells for $ 4 in India" 2107: 1599: 1559: 1524: 1297: 1284:

In September 2020, Gilead announced it had reached a deal to acquire

1154: 1115:

In February 2011, the company acquired Calistoga Pharmaceuticals for

1048: 829: 796: 611: 347: 342: 327: 302: 79: 5176:"New brand-name HIV-prevention pill not worth the added cost: study" 671:

In June 1987, Gilead Sciences was originally founded under the name

5451:"Gilead Seen Cutting Taxes by $ 10 Billion as Pricey Drug Took Off" 5098:"AIDS Activists Take Aim At Gilead To Lower Price Of HIV Drug PrEP" 4403:"The same pill that cost $ 1,000 in the U.S. sold for $ 4 in India" 3347:(Press release). Gilead Sciences. February 22, 2011. Archived from 3322: 3321:(Press release). Gilead Sciences. December 20, 2010. Archived from 3292: 3212: 731:, recipient of the Nobel Prize for Physiology or Medicine in 2009. 7057: 6932: 6852: 6842: 6730: 6700: 6635: 6124: 6054: 6039: 3716:"Gilead buys into multiple myeloma cell therapy with Arcellx deal" 3164:(Press release). Gilead Sciences. November 3, 2006. Archived from 3117: 1237: 1150:) for people at high risk of getting HIV through sexual activity. 1095: 427: 3802:"200,000 Uninsured Americans to Get Free H.I.V.-Prevention Drugs" 3211:(Press release). Gilead Sciences. August 15, 2007. Archived from 1157:, an orally-administered, once-daily, selective inhibitor of the 1008:, a once a day single tablet regimen for HIV, combining Sustiva ( 6510: 4782:

Tourret, Jérôme; Deray, Gilbert; Isnard-Bagnis, Corinne (2013).

2771:

Pandemics, Pills, and Politics: Governing Global Health Security

2732:

Pandemics, Pills, and Politics: Governing Global Health Security

2416:"Senate Report Criticizes Gilead's Pricing Strategy for Sovaldi" 1571: 1532:

for $ 11 billion as "one of the best pharma acquisitions ever".

852: 675:

by Michael L. Riordan, a medical doctor. Riordan graduated from

6767: 5978: 4281:"Gilead and Genesis partner to create novel therapies using AI" 4266:"Novartis, Ono Latest to Announce Billion-Dollar M&A Deals" 2388:"Gilead Deal to Sell Sovaldi in Poor Countries Meets Criticism" 1315:

had purchased a stake in Gilead Sciences on February 26, 2020.

824:

Gilead's antisense intellectual property portfolio was sold to

6917: 6817: 5839:

Ali K, Azher T, Baqi M, Binnie A, et al. (January 2022).

3554:"Gilead Boosts Cancer Pipeline With $ 65M EpiTherapeutics Buy" 3162:"Gilead Sciences Completes Acquisition of Raylo Chemicals Inc" 886: 3030:"Gilead's reliance on CMOs gives firm 'flexibility' says CFO" 2923:. San Francisco: American City Business Journals. p. C1. 658: 3952:

Hammond, Ed; Kirchfeld, Aaron; Nair, Dinesh (June 7, 2020).

921:) achieved first approval in 2001 for the treatment of HIV. 4054:

Lombardo, Cara; Rockoff, Jonathan D. (September 13, 2020).

610:

In the 2000s, Gilead received approval for drugs including

529: 526: 5940: 5774:"Veklury becomes first option for COVID-19 approved in EU" 5588:"No profiteering on COVID-19 drugs and vaccines, says MSF" 5150:"Gilead Will Donate Truvada to U.S. for H.I.V. Prevention" 4642:"Will Gilead's HIV Franchise Plan Be Dashed On TrumpCare?" 4056:"Gilead Reaches Deal to Buy Immunomedics for $ 21 Billion" 3766:"Gilead Will Donate Truvada to U.S. for H.I.V. Prevention" 3572:"Gilead (GILD) Collaborates with Galapagos for Filgotinib" 3110:"U.S. Food And Drug Administration (FDA) Approves Atripla" 3011:"Gilead to Pay $ 464 Million For Triangle Pharmaceuticals" 2863:"FDA approves first generic of Tamiflu for influenza A, B" 2325:"Lawsuit Alleges Price Gouging by Maker of Hepatitis Drug" 873:

In March 1999, Gilead acquired NeXstar Pharmaceuticals of

5513:"US pharma giant Gilead uses 'Double Irish' tax loophole" 3534:"Gilead to Acquire Phenex's FXR Program for Up-to-$ 470M" 2774:. Baltimore: Johns Hopkins University Press. p. 60. 2735:. Baltimore: Johns Hopkins University Press. p. 57. 520: 517: 3981:"AstraZeneca Ponders a Huge $ 240 Billion Gilead Gamble" 3741:"Gilead to buy Cell Design Labs for up to $ 567 million" 3486:"FDA encourages ongoing education of HIV PrEP treatment" 1579:

Sovaldi; in India, a pill's price was as low as $ 4.29.

1168:

It bought Phenex Pharmaceuticals for $ 470 million. Its

5041:

Johnson, Carolyn Y.; Dennis, Brady (December 1, 2015).

3646:"The Giving 20: The Most Generous Companies in America" 2106:

The high price drew the ire of activist groups such as

1228:

In August 2017, the company announced it would acquire

769:) to target specific genetic code sequences – that is, 4676:"Pharma M&A In 2017: The Most Likely Deal Hunters" 4621:"Gilead Sciences, Inc. 2021 Annual Report (Form 10-K)" 4518:"Gilead Sciences, Inc. 2019 Annual Report (Form 10-K)" 4009:"AstraZeneca Approaches Gilead About Potential Merger" 2676:

Moukheiber, Zina; Dolan, Kerry A. (October 27, 2003).

2303:"Gilead Sciences, Inc. 2023 Annual Report (Form 10-K)" 1264:

In March 2020, the company announced it would acquire

1139:

620,000 square feet to about 1.2 million square feet.

758:

as an investor and board member but was unsuccessful.

3056:"Donald Rumsfeld makes $ 5m killing on bird flu drug" 1236:

market and added a chimeric antigen receptor T cell (

687:. The idea for Gilead began as a research project at 659:"The Evolution of HIV/AIDS Therapies: A Conversation" 2609:"History of Gilead Sciences, Inc. – FundingUniverse" 2542:. Washington University in St. Louis. Archived from 742:

to join the board of directors in 1988, followed by

723:, a Nobel laureate who later became Director of the 532: 523: 486: 6503: 6394: 6387: 6012: 5916:. US Food and Drug Administration. January 21, 2022 5891:. US Food and Drug Administration. October 22, 2020 5533:"Remdesivir Orphan Drug Designations and Approvals" 2145:filed a lawsuit on similar grounds against Gilead, 2062:(sold under the brand name Sovaldi), used to treat 637: 514: 481: 465: 445: 425: 405: 385: 366: 220: 183: 173: 162: 154: 136: 115: 68: 58: 4661:"Gilead Sciences: Is an Incyte Deal 'Reasonable'?" 4410: 4224:"Gilead Sciences Completes Acquisition of MiroBio" 3927:"Gilead Completes Acquisition of Forty Seven, Inc" 3897:"Gilead Completes Acquisition of Forty Seven, Inc" 3880: 3748: 1164:In 2015, the company made a trio of acquisitions: 3855:"Gilead to Acquire Forty Seven for $ 4.9 Billion" 3238:"Gilead to Buy CV Therapeutics for $ 1.4 Billion" 2993:"Gilead Sciences to Buy Triangle Pharmaceuticals" 2804:"F.D.A. Approves Gilead's Drug for AIDS Patients" 2515:The Sage Encyclopedia of Pharmacology and Society 2123:In July 2021, Gilead announced it would decrease 4526:. Gilead Sciences. February 2020. Archived from 4137:. December 10, 2020 – via www.reuters.com. 2889:"Roche settles dispute with Gilead over Tamiflu" 2652:"The Nobel Prize in Physiology or Medicine 2009" 7379:Companies associated with the COVID-19 pandemic 3558:Genetic Engineering and Biotechnology News: GEN 3539:Genetic Engineering and Biotechnology News: GEN 3083:"F.D.A. Backs AIDS Pill to Be Taken Once a Day" 2763: 2761: 2759: 2724: 2722: 2720: 2410: 2408: 1318:In November 2021, the company was added to the 599:in 1992, and successfully developed drugs like 5798:. European Medicines Agency. December 22, 2021 5758:: CS1 maint: DOI inactive as of August 2024 ( 6779: 6006:Pharmaceutical companies of the United States 5990: 5506: 5504: 5382: 5380: 4788:Journal of the American Society of Nephrology 4512: 4510: 4508: 4506: 4504: 4502: 4500: 3430:"FDA approves first pill to help prevent HIV" 657:Gregg Alton of Gilead Sciences & others, 548:, that focuses on researching and developing 8: 7384:Pharmaceutical companies established in 1987 7364:Biotechnology companies of the United States 5592:Médecins Sans Frontières (MSF) International 5036: 5034: 5032: 4615: 4613: 4611: 4609: 4607: 4605: 4603: 4498: 4496: 4494: 4492: 4490: 4488: 4486: 4484: 4482: 4480: 4043:. June 23, 2020 – via www.reuters.com. 3266:"Fortune 100 Fastest-Growing Companies 2009" 1142:On July 16, 2012, the FDA approved Gilead's 1055:) in the United States for the treatment of 939:) was approved for the treatment of chronic 32: 7359:Biotechnology companies established in 1987 5889:"FDA Approves First Treatment for COVID-19" 5065: 5063: 4674:Ioannis Stamatopoulos (February 12, 2017). 4324:"Q4 Sovaldi Sales Tracking at $ 53 Million" 3800:McNeil, Jr., Donald G. (December 3, 2019). 2447: 2445: 2443: 2441: 2439: 2381: 2379: 1218:list of The Most Generous Companies of the 7369:Companies based in Foster City, California 6786: 6772: 6764: 6391: 5997: 5983: 5975: 5945: 5908: 5906: 5327: 5325: 5323: 3036:. Crawley: William Reed Business Media Ltd 2986: 2984: 2507: 2505: 2503: 2347: 2345: 1621: 47: 31: 5864: 5727: 5690: 5334:"Pharma combats diversion of cheap drugs" 5225: 4848: 4837:Therapeutics and Clinical Risk Management 4807: 4714: 4148:Stanley-Becker, Isaac (August 12, 2021). 4089:"Gilead Sciences to Acquire Immunomedics" 2964: 2945:Therapeutics and Clinical Risk Management 2699: 2697: 2695: 2693: 2691: 2318: 2316: 2071:United States Senate Committee on Finance 1547:United States Senate Committee on Finance 5820:. Government of Canada. January 17, 2022 5556: 5554: 4833:"Tenofovir-associated bone density loss" 3394: 3392: 2912: 2910: 2488:. Hearst Communications, Inc. p. E1 2475: 2473: 2471: 2469: 2467: 1333:In February 2023, the business, through 1194:, which may treat rheumatoid arthritis, 5096:Simmons-Duffin, Selena (May 30, 2019). 4626:U.S. Securities and Exchange Commission 4523:U.S. Securities and Exchange Commission 4238:"Kite Completes Acquisition of Tmunity" 3293:"Fortune 100 Fastest-Growing Companies" 2452:Rowland, Christopher (March 26, 2019). 2307:U.S. Securities and Exchange Commission 2294: 1340:In February 2024, the company acquired 839:In June 1996, Gilead launched Vistide ( 7339:American companies established in 1987 5751: 5605:Dulan Lokuwithana (October 28, 2021). 5479:"Just Compensation as Transfer Prices" 4353:"Critics Raise Concerns About Sovaldi" 4351:Sanger-Katz, Margot (August 2, 2014). 3764:McNeil, Jr., Donald G. (May 9, 2019). 2708:. San Jose: Knight Ridder. p. 1F. 795:) had been found in modern times in a 713:Fred Hutchinson Cancer Research Center 634: 5511:Paul O'Donoghue (December 26, 2018). 5449:Kocieniewski, David (July 13, 2016). 5275:Rowland, Christopher (May 14, 2019). 5122:Rowland, Christopher (May 16, 2019). 4629:. Gilead Sciences. February 23, 2022. 4279:Priyan, Vishnu (September 11, 2024). 4117:"Gilead Sciences to Acquire MYR GMBH" 3232: 3230: 3112:(Press release). Gilead Sciences and 2802:Fisher, Lawrence M. (June 28, 1996). 2480:Tansey, Bernadette (April 14, 2003). 1072:chronic obstructive pulmonary disease 7: 5845:Canadian Medical Association Journal 5358:Gahlot, Mandakini; Krishnan, Vidya. 4697:Alison R. Walker (January 1, 2016). 4578:"Mission & Core Values – Gilead" 4401:Ketaki Gokhale (December 28, 2015). 2991:Gellene, Denise (December 5, 2002). 2386:Silverman, Ed (September 15, 2014). 2023:tenofovir alafenamide fumarate (TAF) 1320:Dow Jones Sustainability World Index 957:contract manufacturing organizations 836:raised $ 86.25 million in proceeds. 5952:Business data for Gilead Sciences: 5631:Kevin Dunleavy (October 29, 2021). 4553:"Gilead Sciences Revenue 2006–2018" 4471:"I Was Wrong About Gilead Sciences" 2941:"Review of tenofovir-emtricitabine" 2678:"The Golden Age of Antiviral Drugs" 2630:National Institutes of Health (NIH) 2559:"The Golden Age of Antiviral Drugs" 2323:Silverman, Ed (December 19, 2014). 2245:However, over 2020–22 with further 2027:tenofovir disoproxil fumarate (TDF) 1210:and for the potential treatment of 1035:, was a wholly-owned subsidiary of 6284:Pharmaceutical Product Development 5776:. The Pharma Letter. March 7, 2020 5387:Merle, Renae; Johnson, Carolyn Y. 5148:McNeil, Donald G. (May 10, 2019). 5070:Fitzsimmons, Tim (July 19, 2018). 4469:Michael Douglass (March 9, 2017). 4326:. Street Insider. January 3, 2014. 3747:. December 7, 2017. Archived from 3377:(Press release). February 22, 2011 2518:. Sage Publications. p. 657. 2193:reported that Gilead had used the 864:United States Secretary of Defense 677:Washington University in St. Louis 25: 7344:1987 establishments in California 5561:Lupkin, Sydney (March 24, 2020). 5301:Leuty, Ron (September 23, 2021). 3578:. Yahoo/Zack's. December 18, 2015 3490:U.S. Food and Drug Administration 3464:U.S. Food and Drug Administration 3409:. American City Business Journals 3081:Pollack, Andrew (July 13, 2006). 2557:Moukheiber, Kerry A. Dolan Zina. 1307:On August 11, 2021, U.S. Senator 6753:List of pharmaceutical companies 5174:Rapaport, Lisa (March 9, 2020). 5017:Sullivan, Thomas (May 5, 2018). 4898:Petersen, Melody (May 9, 2018). 4756:Petersen, Melody (May 5, 2018). 4730:Jenner, Rob (January 12, 2024). 4640:Allison Gatlin (April 6, 2017). 3714:Bell, Jacob (December 9, 2022). 2540:"1996 Alumni Achievement Awards" 2165:Tax structures and tax avoidance 1104:used for HIV prevention through 843:injection) for the treatment of 681:Johns Hopkins School of Medicine 652: 643: 510: 454: 453: 434: 433: 414: 413: 394: 393: 371: 370: 38: 5423:Silverman, Ed (July 13, 2016). 5249:Ryan, Benjamin (July 7, 2021). 4716:10.1182/blood.V128.22.2831.2831 4659:Ben Levisohn (March 13, 2017). 3879:. March 2, 2020. Archived from 3399:Leuty, Ron (October 19, 2011). 3116:. July 12, 2006. Archived from 2232:In 2021, remdesivir (tradename 2173:. Tax avoidance, as opposed to 2169:Gilead has been criticized for 1043:arena. Under an agreement with 497:Footnotes / references 213:, and senior director, Biology) 27:American pharmaceutical company 7329:Companies listed on the Nasdaq 6938:Coca-Cola Europacific Partners 5332:Kazmin, Amy (April 12, 2015). 4987:Beasley, Deena (May 6, 2020). 4388:"Gilead Q4 2014 Earnings Call" 3933:(Press release). April 7, 2020 3514:(Press release). July 16, 2012 3406:San Francisco Business Journal 2920:San Francisco Business Journal 2265:received approval from the US 1562:) and ranking minority member 1057:primary pulmonary hypertension 89:Nasdaq Biotechnology component 1: 7349:1992 initial public offerings 6160:Institute for OneWorld Health 5477:Blair-Stanek, Andrew (2016). 3492:(Press release). July 1, 2019 3028:Stanton, Dan (May 20, 2015). 2077:The high prices forced state 1252:donated drugs. HHS Secretary 1208:non-alcoholic steatohepatitis 1174:non-alcoholic steatohepatitis 725:National Institutes of Health 471: 6379:West Pharmaceutical Services 5732:(inactive August 20, 2024). 5675:10.1016/j.drudis.2020.11.025 5537:Food and Drug Administration 5307:San Francisco Business Times 2837:"Donald Rumsfeld Fast Facts" 2267:Food and Drug Administration 2220:Food and Drug Administration 1353:Gilead Sciences Acquisitions 1002:Food and Drug Administration 947:) for the treatment of HIV. 870:'s first term as president. 663:Chemical Heritage Foundation 580:. Gilead is a member of the 7354:Biopharmaceutical companies 7324:Companies in the Nasdaq-100 5206:Annals of Internal Medicine 4709:(22). Blood Journal: 2831. 4648:. Investors Business Daily. 4340:. Barrons. January 2, 2014. 2512:Boslaugh, Sarah E. (2015). 2279:Emergency Use Authorization 2210:Gilead sought and obtained 2097:Centers for Disease Control 1031:. Raylo Chemical, based in 754:. Riordan tried to recruit 53:Headquarters in Foster City 7405: 6185:McNeil Consumer Healthcare 3436:. NBC News. Archived from 3150:– via Business Wire. 1510:Treatments for hepatitis C 1408:Calistoga Pharmaceuticals 1296:-hziy) – a first-in-class 893:announced FDA approval of 889:patients. That same year, 6803: 6748: 6691:Smith, Kline & French 6242:Northwest Biotherapeutics 6227:Merrimack Pharmaceuticals 4646:Investor's Business Daily 4440:10.1007/s40265-015-0381-2 4285:Pharmaceutical Technology 3959:The Sydney Morning Herald 3941:– via Businesswire. 3246:. Reuters. March 12, 2009 2125:340B Drug Pricing Program 2000:has shown a 90% complete 1370:Triangle Pharmaceuticals 1068:epithelial sodium channel 651: 642: 552:used in the treatment of 544:company headquartered in 495: 46: 37: 4736:Jenner Law, Baltimore MD 4306:"Grading Pharma in 2013" 2627:"Harold E. Varmus, M.D." 2195:Double Irish arrangement 2159:Médecins Sans Frontières 2132:Anticompetitive behavior 1984:Prospects for the future 1364:NeXstar Pharmaceuticals 1311:disclosed that his wife 1212:hepatocellular carcinoma 1131:by giving it control of 1106:pre-exposure prophylaxis 828:. Gilead debuted on the 765:, or more particularly, 2486:San Francisco Chronicle 2084:Oregon Health Authority 2006:acute myeloid leukaemia 1423:Phenex Pharmaceuticals 1183:involved in regulating 1000:In July 2006, the U.S. 952:San Francisco Chronicle 901:) for the treatment of 834:initial public offering 685:Harvard Business School 597:initial public offering 546:Foster City, California 167:Foster City, California 7374:Life sciences industry 7288:Warner Bros. Discovery 7143:Mondelez International 7103:Marriott International 6923:Charter Communications 6616:Leiner Health Products 6060:Amneal Pharmaceuticals 4800:10.1681/ASN.2012080857 3034:Outsourcing-Pharma.com 2768:Elbe, Stephan (2018). 2729:Elbe, Stephan (2018). 2277:The FDA also provided 2187:On December 26, 2018, 2017:TAF development delays 1545:On July 11, 2014, the 1396:CV Therapeutics, Inc. 1108: 1016:product, and Truvada ( 994:Pseudomonas aeruginosa 991:who are infected with 142:; 37 years ago 6170:Johnson & Johnson 5818:"COVID-19 Treatments" 5023:Policy & Medicine 4415:on December 31, 2015. 4226:. September 20, 2022. 4105:. September 14, 2020. 3608:on September 23, 2021 3375:Gilead Sciences, Inc. 2706:San Jose Mercury News 1497:CymaBay Therapeutics 1461:Tmunity Therapeutics 1302:hepatitis delta virus 1294:Sacituzumab govitecan 1099: 1024:), a Gilead product. 832:in January 1992. Its 826:Ionis Pharmaceuticals 744:Benno C. Schmidt, Sr. 574:ledipasvir/sofosbuvir 506:Gilead Sciences, Inc. 33:Gilead Sciences, Inc. 18:Gilead Sciences, Inc. 7253:Take-Two Interactive 6953:Constellation Energy 6464:Jazz Pharmaceuticals 6454:Horizon Therapeutics 6324:Sarepta Therapeutics 6299:Proteon Therapeutics 6294:Procter & Gamble 6207:Melinta Therapeutics 6100:Bristol Myers Squibb 5663:Drug Discovery Today 4942:on February 26, 2014 4933:Doctors of the World 4312:. December 31, 2013. 4240:. February 22, 2023. 4187:. November 15, 2021. 4119:. December 10, 2020. 3602:investors.gilead.com 3120:on November 15, 2008 3114:Bristol-Myers Squibb 2364:on February 18, 2014 2309:. February 23, 2024. 2151:Teva Pharmaceuticals 2147:Bristol-Myers Squibb 1441:Nimbus Apollo, Inc. 1402:CGI Pharmaceuticals 1342:CymaBay Therapeutics 1181:histone demethylases 1170:Farnesoid X receptor 1022:tenofovir disoproxil 1014:Bristol-Myers Squibb 983:therapeutic arenas. 962:In 2004, during the 806:nucleotide compounds 738:. Riordan recruited 7173:O'Reilly Auto Parts 6671:Repros Therapeutics 6586:Forest Laboratories 6571:Cutter Laboratories 6289:Prasco Laboratories 6030:Acorda Therapeutics 6020:Abbott Laboratories 5857:10.1503/cmaj.211698 5394:The Washington Post 4557:www.macrotrends.net 4390:. February 3, 2015. 4155:The Washington Post 4060:Wall Street Journal 3325:on January 13, 2011 3215:on February 8, 2013 3168:on January 16, 2013 3017:. December 4, 2002. 3015:Wall Street Journal 2895:. November 17, 2005 2613:fundinguniverse.com 2546:on August 21, 2014. 2392:Wall Street Journal 2329:Wall Street Journal 2258:Regulatory approval 2090:Truvada and Descovy 1348:Acquisition history 1330:for $ 405 million. 1053:epoprostenol sodium 928:for $ 200 million. 926:OSI Pharmaceuticals 709:Harold M. Weintraub 467:Number of employees 34: 7228:Roper Technologies 7193:Palo Alto Networks 7068:Intuitive Surgical 7048:Idexx Laboratories 6993:Diamondback Energy 6631:Miles Laboratories 6621:Martek Biosciences 6444:Endo International 6364:Ventria Bioscience 6130:Danco Laboratories 5483:Arizona Law Review 5154:The New York Times 4967:chicagotribune.com 4588:on August 11, 2022 4473:. The Motley Fool. 4358:The New York Times 3885:on March 27, 2022. 3807:The New York Times 3771:The New York Times 3677:. August 28, 2017. 3466:. January 31, 2006 3428:Perrone, Matthew. 3243:The New York Times 3088:The New York Times 2925:Available through 2808:The New York Times 2710:Available through 2424:. December 2, 2015 1384:Corus Pharma, Inc 1196:ulcerative colitis 1185:gene transcription 1109: 1047:, Myogen marketed 199:Andrew Dickinson ( 158:Michael L. Riordan 140:June 22, 1987 7311: 7310: 7268:Texas Instruments 6863:Applied Materials 6794:Companies of the 6761: 6760: 6744: 6743: 6576:DNAPrint Genomics 6065:Avax Technologies 5729:10.1136/bmj.m3379 4961:Gokhale, Ketaki. 4904:Los Angeles Times 4794:(10): 1519–1527. 4762:Los Angeles Times 4533:on March 13, 2022 4338:"Stocks to Watch" 3907:on April 25, 2022 3695:. August 28, 2017 3299:. August 17, 2009 2997:Los Angeles Times 2525:978-1-4833-4999-2 2247:clinical research 2227:COVID-19 pandemic 2117:Rochelle Walensky 1981: 1980: 1520:hepatitis C virus 1500: 1494: 1488: 1482: 1474: 1464: 1458: 1455:Cell Design Labs 1452: 1444: 1438: 1432: 1426: 1420: 1411: 1405: 1399: 1393: 1387: 1381: 1373: 1367: 1129:hepatitis C virus 1033:Edmonton, Alberta 1029:US$ 133.3 million 875:Boulder, Colorado 858:In January 1997, 851:in patients with 771:antisense therapy 669: 668: 542:biopharmaceutical 540:) is an American 503: 502: 459:US$ 22.83 billion 439:US$ 62.13 billion 419:US$ 5.613 billion 399:US$ 7.605 billion 16:(Redirected from 7396: 7153:Monster Beverage 7073:Keurig Dr Pepper 6903:Booking Holdings 6788: 6781: 6774: 6765: 6392: 6339:Tec Laboratories 6212:Melior Discovery 6197:Kinetic Concepts 6140:Galena Biopharma 5999: 5992: 5985: 5976: 5949: 5944: 5943: 5941:Official website 5926: 5925: 5923: 5921: 5910: 5901: 5900: 5898: 5896: 5885: 5879: 5878: 5868: 5851:(7): E242–E251. 5836: 5830: 5829: 5827: 5825: 5814: 5808: 5807: 5805: 5803: 5792: 5786: 5785: 5783: 5781: 5770: 5764: 5763: 5757: 5749: 5731: 5711: 5705: 5704: 5694: 5654: 5648: 5647: 5645: 5643: 5628: 5622: 5621: 5619: 5617: 5602: 5596: 5595: 5584: 5578: 5577: 5575: 5573: 5558: 5549: 5548: 5546: 5544: 5529: 5523: 5522: 5508: 5499: 5498: 5496: 5494: 5474: 5468: 5467: 5465: 5463: 5446: 5440: 5439: 5437: 5435: 5420: 5414: 5413: 5411: 5409: 5384: 5375: 5374: 5372: 5370: 5355: 5349: 5348: 5346: 5344: 5329: 5318: 5317: 5315: 5313: 5298: 5292: 5291: 5289: 5287: 5272: 5266: 5265: 5263: 5261: 5246: 5240: 5239: 5229: 5218:10.7326/m19-3478 5197: 5191: 5190: 5188: 5186: 5171: 5165: 5164: 5162: 5160: 5145: 5139: 5138: 5136: 5134: 5119: 5113: 5112: 5110: 5108: 5093: 5087: 5086: 5084: 5082: 5067: 5058: 5057: 5055: 5053: 5038: 5027: 5026: 5014: 5008: 5007: 5001: 4999: 4984: 4978: 4977: 4975: 4973: 4958: 4952: 4951: 4949: 4947: 4941: 4935:. Archived from 4930: 4921: 4915: 4914: 4912: 4910: 4895: 4889: 4888: 4886: 4884: 4879:. April 11, 2019 4869: 4863: 4862: 4852: 4828: 4822: 4821: 4811: 4779: 4773: 4772: 4770: 4768: 4753: 4747: 4746: 4744: 4742: 4727: 4721: 4720: 4718: 4694: 4688: 4687: 4685: 4683: 4671: 4665: 4664: 4656: 4650: 4649: 4637: 4631: 4630: 4617: 4598: 4597: 4595: 4593: 4584:. Archived from 4574: 4568: 4567: 4565: 4563: 4549: 4543: 4542: 4540: 4538: 4532: 4514: 4475: 4474: 4466: 4460: 4459: 4423: 4417: 4416: 4414: 4409:. Archived from 4398: 4392: 4391: 4384: 4378: 4377: 4375: 4373: 4348: 4342: 4341: 4334: 4328: 4327: 4320: 4314: 4313: 4302: 4296: 4295: 4293: 4291: 4276: 4270: 4269: 4268:. March 5, 2024. 4262: 4256: 4255: 4248: 4242: 4241: 4234: 4228: 4227: 4220: 4214: 4213: 4211: 4209: 4195: 4189: 4188: 4181: 4175: 4174: 4172: 4170: 4145: 4139: 4138: 4127: 4121: 4120: 4113: 4107: 4106: 4099: 4093: 4092: 4085: 4079: 4078: 4076: 4074: 4051: 4045: 4044: 4033: 4027: 4026: 4024: 4022: 4005: 3999: 3998: 3996: 3994: 3977: 3971: 3970: 3968: 3966: 3949: 3943: 3942: 3940: 3938: 3923: 3917: 3916: 3914: 3912: 3903:. Archived from 3893: 3887: 3886: 3884: 3869: 3863: 3862: 3851: 3845: 3844: 3843:. March 2, 2020. 3833: 3827: 3826: 3824: 3822: 3797: 3791: 3790: 3788: 3786: 3761: 3755: 3754: 3753:on June 6, 2020. 3752: 3737: 3731: 3730: 3728: 3726: 3711: 3705: 3704: 3702: 3700: 3693:fiercepharma.com 3685: 3679: 3678: 3667: 3661: 3660: 3658: 3656: 3642: 3636: 3635: 3634:. April 6, 2016. 3624: 3618: 3617: 3615: 3613: 3604:. Archived from 3594: 3588: 3587: 3585: 3583: 3568: 3562: 3561: 3550: 3544: 3543: 3530: 3524: 3523: 3521: 3519: 3508: 3502: 3501: 3499: 3497: 3482: 3476: 3475: 3473: 3471: 3456: 3450: 3449: 3447: 3445: 3440:on July 16, 2012 3425: 3419: 3418: 3416: 3414: 3396: 3387: 3386: 3384: 3382: 3367: 3361: 3360: 3358: 3356: 3341: 3335: 3334: 3332: 3330: 3315: 3309: 3308: 3306: 3304: 3289: 3283: 3282: 3280: 3278: 3262: 3256: 3255: 3253: 3251: 3234: 3225: 3224: 3222: 3220: 3205: 3199: 3198: 3196: 3194: 3184: 3178: 3177: 3175: 3173: 3158: 3152: 3151: 3149: 3147: 3136: 3130: 3129: 3127: 3125: 3106: 3100: 3099: 3097: 3095: 3078: 3072: 3071: 3069: 3067: 3062:. March 12, 2006 3052: 3046: 3045: 3043: 3041: 3025: 3019: 3018: 3007: 3001: 3000: 2988: 2979: 2978: 2968: 2951:(6): 1097–1104. 2936: 2930: 2924: 2914: 2905: 2904: 2902: 2900: 2885: 2879: 2878: 2876: 2874: 2869:. August 4, 2016 2859: 2853: 2852: 2850: 2848: 2833: 2827: 2826: 2824: 2822: 2799: 2793: 2792: 2790: 2788: 2765: 2754: 2753: 2751: 2749: 2726: 2715: 2709: 2701: 2686: 2685: 2673: 2667: 2666: 2664: 2662: 2648: 2642: 2641: 2639: 2637: 2632:. August 6, 2015 2623: 2617: 2616: 2605: 2599: 2598: 2596: 2594: 2580: 2574: 2573: 2571: 2569: 2554: 2548: 2547: 2536: 2530: 2529: 2509: 2498: 2497: 2495: 2493: 2477: 2462: 2461: 2449: 2434: 2433: 2431: 2429: 2412: 2403: 2402: 2400: 2398: 2383: 2374: 2373: 2371: 2369: 2360:. Archived from 2349: 2340: 2339: 2337: 2335: 2320: 2311: 2310: 2299: 2251:Solidarity Trial 2214:designation for 2200: 2182:transfer pricing 1622: 1586:and marketed as 1498: 1492: 1486: 1480: 1472: 1462: 1456: 1450: 1442: 1436: 1430: 1429:EpiTherapeutics 1424: 1418: 1409: 1403: 1397: 1391: 1390:Raylo Chemicals 1385: 1379: 1371: 1365: 1266:Forty Seven Inc. 1122: 1121:US$ 10.4 billion 1118: 1030: 767:oligonucleotides 752:George P. Shultz 656: 655: 647: 635: 593:oligonucleotides 539: 538: 535: 534: 531: 528: 525: 522: 519: 516: 491: 488: 476: 473: 460: 457: 456: 450: 440: 437: 436: 430: 420: 417: 416: 400: 397: 396: 388:Operating income 380: 374: 373: 194:chairman and CEO 150: 148: 143: 51: 42: 35: 21: 7404: 7403: 7399: 7398: 7397: 7395: 7394: 7393: 7389:Specialty drugs 7334:Gilead Sciences 7314: 7313: 7312: 7307: 7038:GlobalFoundries 7008:Electronic Arts 6799: 6792: 6762: 6757: 6740: 6686:Schering-Plough 6596:ImClone Systems 6499: 6383: 6232:Myriad Genetics 6222:Merck & Co. 6180:Janssen Biotech 6150:Gilead Sciences 6008: 6003: 5971: 5939: 5938: 5935: 5930: 5929: 5919: 5917: 5912: 5911: 5904: 5894: 5892: 5887: 5886: 5882: 5838: 5837: 5833: 5823: 5821: 5816: 5815: 5811: 5801: 5799: 5794: 5793: 5789: 5779: 5777: 5772: 5771: 5767: 5750: 5713: 5712: 5708: 5656: 5655: 5651: 5641: 5639: 5630: 5629: 5625: 5615: 5613: 5604: 5603: 5599: 5586: 5585: 5581: 5571: 5569: 5560: 5559: 5552: 5542: 5540: 5531: 5530: 5526: 5510: 5509: 5502: 5492: 5490: 5476: 5475: 5471: 5461: 5459: 5448: 5447: 5443: 5433: 5431: 5422: 5421: 5417: 5407: 5405: 5386: 5385: 5378: 5368: 5366: 5357: 5356: 5352: 5342: 5340: 5338:Financial Times 5331: 5330: 5321: 5311: 5309: 5300: 5299: 5295: 5285: 5283: 5281:Washington Post 5274: 5273: 5269: 5259: 5257: 5248: 5247: 5243: 5199: 5198: 5194: 5184: 5182: 5173: 5172: 5168: 5158: 5156: 5147: 5146: 5142: 5132: 5130: 5128:Washington Post 5121: 5120: 5116: 5106: 5104: 5095: 5094: 5090: 5080: 5078: 5069: 5068: 5061: 5051: 5049: 5047:Washington Post 5040: 5039: 5030: 5016: 5015: 5011: 4997: 4995: 4986: 4985: 4981: 4971: 4969: 4960: 4959: 4955: 4945: 4943: 4939: 4928: 4923: 4922: 4918: 4908: 4906: 4897: 4896: 4892: 4882: 4880: 4871: 4870: 4866: 4830: 4829: 4825: 4781: 4780: 4776: 4766: 4764: 4755: 4754: 4750: 4740: 4738: 4729: 4728: 4724: 4696: 4695: 4691: 4681: 4679: 4678:. Seeking Alpha 4673: 4672: 4668: 4658: 4657: 4653: 4639: 4638: 4634: 4619: 4618: 4601: 4591: 4589: 4576: 4575: 4571: 4561: 4559: 4551: 4550: 4546: 4536: 4534: 4530: 4516: 4515: 4478: 4468: 4467: 4463: 4425: 4424: 4420: 4400: 4399: 4395: 4386: 4385: 4381: 4371: 4369: 4350: 4349: 4345: 4336: 4335: 4331: 4322: 4321: 4317: 4304: 4303: 4299: 4289: 4287: 4278: 4277: 4273: 4264: 4263: 4259: 4250: 4249: 4245: 4236: 4235: 4231: 4222: 4221: 4217: 4207: 4205: 4197: 4196: 4192: 4183: 4182: 4178: 4168: 4166: 4147: 4146: 4142: 4129: 4128: 4124: 4115: 4114: 4110: 4101: 4100: 4096: 4087: 4086: 4082: 4072: 4070: 4053: 4052: 4048: 4035: 4034: 4030: 4020: 4018: 4007: 4006: 4002: 3992: 3990: 3979: 3978: 3974: 3964: 3962: 3951: 3950: 3946: 3936: 3934: 3931:Gilead Sciences 3925: 3924: 3920: 3910: 3908: 3901:Gilead Sciences 3895: 3894: 3890: 3871: 3870: 3866: 3853: 3852: 3848: 3835: 3834: 3830: 3820: 3818: 3799: 3798: 3794: 3784: 3782: 3763: 3762: 3758: 3739: 3738: 3734: 3724: 3722: 3713: 3712: 3708: 3698: 3696: 3687: 3686: 3682: 3669: 3668: 3664: 3654: 3652: 3644: 3643: 3639: 3626: 3625: 3621: 3611: 3609: 3596: 3595: 3591: 3581: 3579: 3570: 3569: 3565: 3552: 3551: 3547: 3532: 3531: 3527: 3517: 3515: 3510: 3509: 3505: 3495: 3493: 3484: 3483: 3479: 3469: 3467: 3458: 3457: 3453: 3443: 3441: 3427: 3426: 3422: 3412: 3410: 3398: 3397: 3390: 3380: 3378: 3369: 3368: 3364: 3354: 3352: 3351:on July 9, 2012 3343: 3342: 3338: 3328: 3326: 3317: 3316: 3312: 3302: 3300: 3291: 3290: 3286: 3276: 3274: 3264: 3263: 3259: 3249: 3247: 3236: 3235: 3228: 3218: 3216: 3207: 3206: 3202: 3192: 3190: 3186: 3185: 3181: 3171: 3169: 3160: 3159: 3155: 3145: 3143: 3138: 3137: 3133: 3123: 3121: 3108: 3107: 3103: 3093: 3091: 3080: 3079: 3075: 3065: 3063: 3060:The Independent 3054: 3053: 3049: 3039: 3037: 3027: 3026: 3022: 3009: 3008: 3004: 2990: 2989: 2982: 2938: 2937: 2933: 2916: 2915: 2908: 2898: 2896: 2887: 2886: 2882: 2872: 2870: 2861: 2860: 2856: 2846: 2844: 2843:. June 27, 2019 2835: 2834: 2830: 2820: 2818: 2801: 2800: 2796: 2786: 2784: 2782: 2767: 2766: 2757: 2747: 2745: 2743: 2728: 2727: 2718: 2703: 2702: 2689: 2675: 2674: 2670: 2660: 2658: 2650: 2649: 2645: 2635: 2633: 2625: 2624: 2620: 2607: 2606: 2602: 2592: 2590: 2582: 2581: 2577: 2567: 2565: 2556: 2555: 2551: 2538: 2537: 2533: 2526: 2511: 2510: 2501: 2491: 2489: 2479: 2478: 2465: 2458:Washington Post 2451: 2450: 2437: 2427: 2425: 2414: 2413: 2406: 2396: 2394: 2385: 2384: 2377: 2367: 2365: 2351: 2350: 2343: 2333: 2331: 2322: 2321: 2314: 2301: 2300: 2296: 2291: 2260: 2242: 2208: 2198: 2167: 2134: 2092: 2056: 2051: 2019: 2014: 1986: 1644: 1643:Price per share 1639: 1634: 1629: 1616: 1574:) wrote to CEO 1512: 1507: 1506: 1505: 1360:Gilead Sciences 1354: 1350: 1278:AstraZeneca Plc 1262: 1200:Crohn's disease 1120: 1117:US$ 375 million 1116: 1094: 1045:GlaxoSmithKline 1028: 1004:(FDA) approved 989:cystic fibrosis 969:Donald Rumsfeld 943:, and Emtriva ( 915: 860:Donald Rumsfeld 845:cytomegalovirus 822: 740:Donald Rumsfeld 653: 638:External videos 633: 628: 550:antiviral drugs 513: 509: 499: 485: 474: 468: 458: 446: 438: 426: 418: 410: 398: 390: 375: 362: 216: 186: 176: 169:, United States 146: 144: 141: 132: 111: 73: 54: 28: 23: 22: 15: 12: 11: 5: 7402: 7400: 7392: 7391: 7386: 7381: 7376: 7371: 7366: 7361: 7356: 7351: 7346: 7341: 7336: 7331: 7326: 7316: 7315: 7309: 7308: 7306: 7305: 7300: 7295: 7290: 7285: 7280: 7275: 7270: 7265: 7260: 7255: 7250: 7245: 7240: 7235: 7230: 7225: 7220: 7215: 7210: 7205: 7200: 7195: 7190: 7185: 7180: 7175: 7170: 7165: 7160: 7155: 7150: 7145: 7140: 7135: 7130: 7125: 7120: 7115: 7110: 7105: 7100: 7095: 7090: 7085: 7080: 7075: 7070: 7065: 7060: 7055: 7050: 7045: 7040: 7035: 7030: 7025: 7020: 7015: 7010: 7005: 7000: 6995: 6990: 6985: 6980: 6975: 6970: 6965: 6960: 6955: 6950: 6945: 6940: 6935: 6930: 6925: 6920: 6915: 6910: 6905: 6900: 6895: 6890: 6885: 6880: 6875: 6870: 6865: 6860: 6855: 6850: 6848:Analog Devices 6845: 6840: 6835: 6830: 6825: 6820: 6815: 6810: 6804: 6801: 6800: 6793: 6791: 6790: 6783: 6776: 6768: 6759: 6758: 6756: 6755: 6749: 6746: 6745: 6742: 6741: 6739: 6738: 6733: 6728: 6723: 6718: 6713: 6708: 6703: 6698: 6693: 6688: 6683: 6678: 6673: 6668: 6663: 6658: 6653: 6648: 6643: 6638: 6633: 6628: 6623: 6618: 6613: 6608: 6603: 6598: 6593: 6588: 6583: 6578: 6573: 6568: 6563: 6558: 6553: 6548: 6543: 6538: 6533: 6528: 6523: 6518: 6516:Allergan, Inc. 6513: 6507: 6505: 6501: 6500: 6498: 6497: 6496:(Canada, 2010) 6491: 6481: 6471: 6461: 6451: 6441: 6431: 6421: 6411: 6400: 6398: 6389: 6385: 6384: 6382: 6381: 6376: 6371: 6366: 6361: 6356: 6351: 6346: 6341: 6336: 6331: 6326: 6321: 6316: 6311: 6306: 6301: 6296: 6291: 6286: 6281: 6280: 6279: 6274: 6264: 6259: 6254: 6249: 6247:Norwich Pharma 6244: 6239: 6234: 6229: 6224: 6219: 6214: 6209: 6204: 6199: 6194: 6193: 6192: 6187: 6182: 6177: 6167: 6162: 6157: 6152: 6147: 6142: 6137: 6132: 6127: 6122: 6117: 6112: 6107: 6102: 6097: 6092: 6087: 6082: 6077: 6072: 6067: 6062: 6057: 6052: 6047: 6042: 6037: 6032: 6027: 6022: 6016: 6014: 6010: 6009: 6004: 6002: 6001: 5994: 5987: 5979: 5973: 5972: 5970: 5969: 5964: 5959: 5953: 5950: 5934: 5933:External links 5931: 5928: 5927: 5902: 5880: 5831: 5809: 5787: 5765: 5706: 5669:(2): 593–603. 5649: 5623: 5597: 5579: 5550: 5524: 5500: 5469: 5456:Bloomberg News 5441: 5415: 5376: 5350: 5319: 5293: 5267: 5241: 5212:(9): 583–590. 5192: 5166: 5140: 5114: 5088: 5059: 5028: 5009: 4979: 4953: 4916: 4890: 4864: 4823: 4774: 4748: 4722: 4689: 4666: 4651: 4632: 4599: 4582:www.gilead.com 4569: 4544: 4476: 4461: 4418: 4407:Bloomberg News 4393: 4379: 4343: 4329: 4315: 4297: 4271: 4257: 4254:. May 9, 2023. 4243: 4229: 4215: 4203:www.gilead.com 4190: 4176: 4140: 4122: 4108: 4094: 4080: 4046: 4028: 4017:. June 7, 2020 4014:Bloomberg News 4000: 3989:. June 7, 2020 3972: 3944: 3918: 3888: 3864: 3846: 3828: 3792: 3756: 3732: 3720:BioPharma Dive 3706: 3680: 3662: 3637: 3619: 3589: 3563: 3560:. May 6, 2015. 3545: 3525: 3503: 3477: 3451: 3420: 3388: 3362: 3336: 3310: 3284: 3257: 3226: 3200: 3179: 3153: 3131: 3101: 3073: 3047: 3020: 3002: 2980: 2931: 2906: 2880: 2867:www.healio.com 2854: 2828: 2794: 2780: 2755: 2741: 2716: 2687: 2668: 2656:NobelPrize.org 2643: 2618: 2600: 2575: 2549: 2531: 2524: 2499: 2463: 2435: 2404: 2375: 2341: 2312: 2293: 2292: 2290: 2287: 2259: 2256: 2241: 2238: 2207: 2204: 2166: 2163: 2133: 2130: 2091: 2088: 2055: 2052: 2050: 2047: 2043:nephrotoxicity 2031:nephrotoxicity 2018: 2015: 2013: 2010: 1985: 1982: 1979: 1978: 1975: 1973: 1970: 1967: 1964: 1960: 1959: 1956: 1954: 1951: 1948: 1945: 1941: 1940: 1937: 1935: 1932: 1929: 1926: 1922: 1921: 1918: 1915: 1912: 1909: 1906: 1902: 1901: 1898: 1895: 1892: 1889: 1886: 1882: 1881: 1878: 1875: 1872: 1869: 1866: 1862: 1861: 1858: 1855: 1852: 1849: 1846: 1842: 1841: 1838: 1835: 1832: 1829: 1826: 1822: 1821: 1818: 1815: 1812: 1809: 1806: 1802: 1801: 1799: 1796: 1793: 1790: 1787: 1783: 1782: 1780: 1777: 1774: 1771: 1768: 1764: 1763: 1761: 1758: 1755: 1752: 1749: 1745: 1744: 1742: 1739: 1736: 1733: 1730: 1726: 1725: 1723: 1720: 1717: 1714: 1711: 1707: 1706: 1704: 1701: 1698: 1695: 1692: 1688: 1687: 1685: 1682: 1679: 1676: 1673: 1669: 1668: 1666: 1663: 1660: 1657: 1654: 1650: 1649: 1646: 1641: 1640:in mil. USD$ 1636: 1635:in mil. USD$ 1631: 1630:in mil. USD$ 1626: 1619:October 2018. 1615: 1612: 1576:John C. Martin 1564:Chuck Grassley 1511: 1508: 1504: 1503: 1502: 1501: 1495: 1489: 1483: 1475: 1467: 1466: 1465: 1459: 1445: 1439: 1433: 1427: 1421: 1412: 1406: 1400: 1394: 1388: 1382: 1374: 1368: 1356: 1355: 1352: 1351: 1349: 1346: 1276:reported that 1272:In June 2020, 1261: 1258: 1204: 1203: 1188: 1177: 1093: 1090: 1076:bronchiectasis 977:cardiovascular 914: 911: 885:drug taken by 868:George W. Bush 821: 820:1990–1999: IPO 818: 788:Balm in Gilead 783:Lanford Wilson 779:Balm of Gilead 756:Warren Buffett 717:Menlo Ventures 689:Menlo Ventures 667: 666: 649: 648: 640: 639: 632: 629: 627: 624: 501: 500: 493: 492: 483: 479: 478: 469: 466: 463: 462: 451: 443: 442: 431: 423: 422: 411: 406: 403: 402: 391: 386: 383: 382: 368: 364: 363: 361: 360: 355: 350: 345: 340: 335: 330: 325: 320: 315: 310: 305: 300: 295: 290: 285: 280: 275: 270: 265: 260: 255: 250: 245: 240: 235: 230: 224: 222: 218: 217: 215: 214: 211:vice president 204: 197: 192:Daniel O'Day ( 189: 187: 184: 181: 180: 177: 174: 171: 170: 164: 160: 159: 156: 152: 151: 138: 134: 133: 131: 130: 125: 119: 117: 113: 112: 110: 109: 103: 97: 91: 86: 76: 74: 69: 66: 65: 60: 56: 55: 52: 44: 43: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 7401: 7390: 7387: 7385: 7382: 7380: 7377: 7375: 7372: 7370: 7367: 7365: 7362: 7360: 7357: 7355: 7352: 7350: 7347: 7345: 7342: 7340: 7337: 7335: 7332: 7330: 7327: 7325: 7322: 7321: 7319: 7304: 7301: 7299: 7296: 7294: 7291: 7289: 7286: 7284: 7281: 7279: 7276: 7274: 7271: 7269: 7266: 7264: 7261: 7259: 7256: 7254: 7251: 7249: 7246: 7244: 7241: 7239: 7236: 7234: 7231: 7229: 7226: 7224: 7221: 7219: 7216: 7214: 7211: 7209: 7206: 7204: 7201: 7199: 7196: 7194: 7191: 7189: 7186: 7184: 7181: 7179: 7176: 7174: 7171: 7169: 7166: 7164: 7161: 7159: 7156: 7154: 7151: 7149: 7146: 7144: 7141: 7139: 7136: 7134: 7131: 7129: 7126: 7124: 7121: 7119: 7116: 7114: 7113:Mercado Libre 7111: 7109: 7106: 7104: 7101: 7099: 7096: 7094: 7091: 7089: 7086: 7084: 7081: 7079: 7076: 7074: 7071: 7069: 7066: 7064: 7061: 7059: 7056: 7054: 7051: 7049: 7046: 7044: 7041: 7039: 7036: 7034: 7031: 7029: 7028:GE HealthCare 7026: 7024: 7021: 7019: 7016: 7014: 7011: 7009: 7006: 7004: 7001: 6999: 6996: 6994: 6991: 6989: 6986: 6984: 6981: 6979: 6976: 6974: 6971: 6969: 6966: 6964: 6961: 6959: 6956: 6954: 6951: 6949: 6946: 6944: 6941: 6939: 6936: 6934: 6931: 6929: 6926: 6924: 6921: 6919: 6916: 6914: 6911: 6909: 6906: 6904: 6901: 6899: 6896: 6894: 6891: 6889: 6886: 6884: 6881: 6879: 6876: 6874: 6871: 6869: 6866: 6864: 6861: 6859: 6856: 6854: 6851: 6849: 6846: 6844: 6841: 6839: 6836: 6834: 6831: 6829: 6826: 6824: 6821: 6819: 6816: 6814: 6811: 6809: 6806: 6805: 6802: 6797: 6789: 6784: 6782: 6777: 6775: 6770: 6769: 6766: 6754: 6751: 6750: 6747: 6737: 6734: 6732: 6729: 6727: 6724: 6722: 6719: 6717: 6714: 6712: 6709: 6707: 6704: 6702: 6699: 6697: 6696:Sterling Drug 6694: 6692: 6689: 6687: 6684: 6682: 6679: 6677: 6674: 6672: 6669: 6667: 6664: 6662: 6659: 6657: 6654: 6652: 6649: 6647: 6644: 6642: 6639: 6637: 6634: 6632: 6629: 6627: 6624: 6622: 6619: 6617: 6614: 6612: 6609: 6607: 6604: 6602: 6599: 6597: 6594: 6592: 6589: 6587: 6584: 6582: 6579: 6577: 6574: 6572: 6569: 6567: 6564: 6562: 6559: 6557: 6554: 6552: 6549: 6547: 6544: 6542: 6539: 6537: 6534: 6532: 6529: 6527: 6524: 6522: 6519: 6517: 6514: 6512: 6509: 6508: 6506: 6502: 6495: 6494:Bausch Health 6492: 6489: 6485: 6482: 6479: 6475: 6472: 6469: 6465: 6462: 6459: 6455: 6452: 6449: 6445: 6442: 6439: 6435: 6432: 6429: 6425: 6422: 6419: 6415: 6412: 6409: 6405: 6402: 6401: 6399: 6397: 6396:Tax inversion 6393: 6390: 6386: 6380: 6377: 6375: 6372: 6370: 6367: 6365: 6362: 6360: 6357: 6355: 6352: 6350: 6347: 6345: 6342: 6340: 6337: 6335: 6332: 6330: 6327: 6325: 6322: 6320: 6317: 6315: 6312: 6310: 6307: 6305: 6304:Purdue Pharma 6302: 6300: 6297: 6295: 6292: 6290: 6287: 6285: 6282: 6278: 6275: 6273: 6270: 6269: 6268: 6265: 6263: 6260: 6258: 6255: 6253: 6250: 6248: 6245: 6243: 6240: 6238: 6235: 6233: 6230: 6228: 6225: 6223: 6220: 6218: 6215: 6213: 6210: 6208: 6205: 6203: 6200: 6198: 6195: 6191: 6188: 6186: 6183: 6181: 6178: 6176: 6173: 6172: 6171: 6168: 6166: 6163: 6161: 6158: 6156: 6153: 6151: 6148: 6146: 6143: 6141: 6138: 6136: 6133: 6131: 6128: 6126: 6123: 6121: 6118: 6116: 6113: 6111: 6108: 6106: 6103: 6101: 6098: 6096: 6093: 6091: 6088: 6086: 6083: 6081: 6078: 6076: 6073: 6071: 6068: 6066: 6063: 6061: 6058: 6056: 6053: 6051: 6048: 6046: 6043: 6041: 6038: 6036: 6033: 6031: 6028: 6026: 6023: 6021: 6018: 6017: 6015: 6011: 6007: 6000: 5995: 5993: 5988: 5986: 5981: 5980: 5977: 5968: 5965: 5963: 5960: 5958: 5955: 5954: 5951: 5948: 5942: 5937: 5936: 5932: 5915: 5909: 5907: 5903: 5890: 5884: 5881: 5876: 5872: 5867: 5862: 5858: 5854: 5850: 5846: 5842: 5835: 5832: 5819: 5813: 5810: 5797: 5791: 5788: 5775: 5769: 5766: 5761: 5755: 5747: 5743: 5739: 5735: 5730: 5725: 5721: 5717: 5710: 5707: 5702: 5698: 5693: 5688: 5684: 5680: 5676: 5672: 5668: 5664: 5660: 5653: 5650: 5638: 5637:Fierce Pharma 5634: 5627: 5624: 5612: 5611:Seeking Alpha 5608: 5601: 5598: 5593: 5589: 5583: 5580: 5568: 5564: 5557: 5555: 5551: 5538: 5534: 5528: 5525: 5520: 5519: 5514: 5507: 5505: 5501: 5488: 5484: 5480: 5473: 5470: 5458: 5457: 5452: 5445: 5442: 5430: 5426: 5419: 5416: 5404: 5400: 5396: 5395: 5390: 5383: 5381: 5377: 5365: 5361: 5354: 5351: 5343:September 27, 5339: 5335: 5328: 5326: 5324: 5320: 5312:September 27, 5308: 5304: 5297: 5294: 5286:September 27, 5282: 5278: 5271: 5268: 5260:September 23, 5256: 5252: 5245: 5242: 5237: 5233: 5228: 5223: 5219: 5215: 5211: 5207: 5203: 5196: 5193: 5185:September 23, 5181: 5177: 5170: 5167: 5159:September 20, 5155: 5151: 5144: 5141: 5133:September 19, 5129: 5125: 5118: 5115: 5107:September 19, 5103: 5099: 5092: 5089: 5081:September 19, 5077: 5073: 5066: 5064: 5060: 5052:September 19, 5048: 5044: 5037: 5035: 5033: 5029: 5024: 5020: 5013: 5010: 5006: 4998:September 19, 4994: 4990: 4983: 4980: 4972:September 19, 4968: 4964: 4957: 4954: 4938: 4934: 4927: 4920: 4917: 4905: 4901: 4894: 4891: 4878: 4877:Business Wire 4874: 4868: 4865: 4860: 4856: 4851: 4846: 4842: 4838: 4834: 4827: 4824: 4819: 4815: 4810: 4805: 4801: 4797: 4793: 4789: 4785: 4778: 4775: 4763: 4759: 4752: 4749: 4737: 4733: 4726: 4723: 4717: 4712: 4708: 4704: 4700: 4693: 4690: 4677: 4670: 4667: 4662: 4655: 4652: 4647: 4643: 4636: 4633: 4628: 4627: 4622: 4616: 4614: 4612: 4610: 4608: 4606: 4604: 4600: 4587: 4583: 4579: 4573: 4570: 4558: 4554: 4548: 4545: 4529: 4525: 4524: 4519: 4513: 4511: 4509: 4507: 4505: 4503: 4501: 4499: 4497: 4495: 4493: 4491: 4489: 4487: 4485: 4483: 4481: 4477: 4472: 4465: 4462: 4457: 4453: 4449: 4445: 4441: 4437: 4434:(6): 675–85. 4433: 4429: 4422: 4419: 4413: 4408: 4404: 4397: 4394: 4389: 4383: 4380: 4368: 4364: 4360: 4359: 4354: 4347: 4344: 4339: 4333: 4330: 4325: 4319: 4316: 4311: 4307: 4301: 4298: 4290:September 16, 4286: 4282: 4275: 4272: 4267: 4261: 4258: 4253: 4247: 4244: 4239: 4233: 4230: 4225: 4219: 4216: 4204: 4200: 4194: 4191: 4186: 4180: 4177: 4165: 4161: 4157: 4156: 4151: 4144: 4141: 4136: 4132: 4126: 4123: 4118: 4112: 4109: 4104: 4098: 4095: 4090: 4084: 4081: 4073:September 13, 4069: 4065: 4061: 4057: 4050: 4047: 4042: 4038: 4032: 4029: 4016: 4015: 4010: 4004: 4001: 3988: 3987: 3986:Bloomberg Law 3982: 3976: 3973: 3961: 3960: 3955: 3948: 3945: 3932: 3928: 3922: 3919: 3906: 3902: 3898: 3892: 3889: 3883: 3878: 3874: 3868: 3865: 3860: 3856: 3850: 3847: 3842: 3838: 3832: 3829: 3817: 3813: 3809: 3808: 3803: 3796: 3793: 3781: 3777: 3773: 3772: 3767: 3760: 3757: 3751: 3746: 3742: 3736: 3733: 3721: 3717: 3710: 3707: 3694: 3690: 3684: 3681: 3676: 3672: 3666: 3663: 3651: 3647: 3641: 3638: 3633: 3632:Parent Herald 3629: 3623: 3620: 3612:September 23, 3607: 3603: 3599: 3593: 3590: 3577: 3576:Yahoo Finance 3573: 3567: 3564: 3559: 3555: 3549: 3546: 3541: 3540: 3535: 3529: 3526: 3513: 3507: 3504: 3491: 3487: 3481: 3478: 3465: 3461: 3455: 3452: 3439: 3435: 3431: 3424: 3421: 3408: 3407: 3402: 3395: 3393: 3389: 3376: 3372: 3366: 3363: 3350: 3346: 3340: 3337: 3324: 3320: 3314: 3311: 3298: 3294: 3288: 3285: 3273: 3272: 3267: 3261: 3258: 3245: 3244: 3239: 3233: 3231: 3227: 3214: 3210: 3204: 3201: 3189: 3183: 3180: 3167: 3163: 3157: 3154: 3141: 3135: 3132: 3119: 3115: 3111: 3105: 3102: 3094:September 20, 3090: 3089: 3084: 3077: 3074: 3061: 3057: 3051: 3048: 3035: 3031: 3024: 3021: 3016: 3012: 3006: 3003: 2998: 2994: 2987: 2985: 2981: 2976: 2972: 2967: 2962: 2958: 2954: 2950: 2946: 2942: 2935: 2932: 2928: 2922: 2921: 2913: 2911: 2907: 2899:September 19, 2894: 2890: 2884: 2881: 2868: 2864: 2858: 2855: 2842: 2838: 2832: 2829: 2821:September 22, 2817: 2813: 2809: 2805: 2798: 2795: 2783: 2781:9781421425580 2777: 2773: 2772: 2764: 2762: 2760: 2756: 2744: 2742:9781421425580 2738: 2734: 2733: 2725: 2723: 2721: 2717: 2713: 2707: 2700: 2698: 2696: 2694: 2692: 2688: 2683: 2679: 2672: 2669: 2657: 2653: 2647: 2644: 2631: 2628: 2622: 2619: 2614: 2610: 2604: 2601: 2589: 2585: 2579: 2576: 2564: 2560: 2553: 2550: 2545: 2541: 2535: 2532: 2527: 2521: 2517: 2516: 2508: 2506: 2504: 2500: 2487: 2483: 2476: 2474: 2472: 2470: 2468: 2464: 2459: 2455: 2448: 2446: 2444: 2442: 2440: 2436: 2428:September 19, 2423: 2422: 2421:Bloomberg Law 2417: 2411: 2409: 2405: 2397:September 19, 2393: 2389: 2382: 2380: 2376: 2363: 2359: 2355: 2348: 2346: 2342: 2334:September 19, 2330: 2326: 2319: 2317: 2313: 2308: 2304: 2298: 2295: 2288: 2286: 2284: 2280: 2275: 2272: 2268: 2264: 2257: 2255: 2252: 2248: 2239: 2237: 2235: 2230: 2228: 2223: 2221: 2217: 2213: 2205: 2203: 2196: 2192: 2191: 2185: 2183: 2178: 2176: 2172: 2171:tax avoidance 2164: 2162: 2160: 2154: 2152: 2148: 2144: 2140: 2131: 2129: 2126: 2121: 2118: 2112: 2109: 2104: 2100: 2098: 2089: 2087: 2085: 2080: 2075: 2072: 2067: 2065: 2061: 2053: 2048: 2046: 2044: 2038: 2036: 2032: 2028: 2024: 2016: 2011: 2009: 2007: 2004:for MLL type 2003: 2002:response rate 1999: 1998:Entospletinib 1994: 1991: 1983: 1976: 1974: 1971: 1968: 1965: 1962: 1961: 1957: 1955: 1952: 1949: 1946: 1943: 1942: 1938: 1936: 1933: 1930: 1927: 1924: 1923: 1919: 1916: 1913: 1910: 1907: 1904: 1903: 1899: 1896: 1893: 1890: 1887: 1884: 1883: 1879: 1876: 1873: 1870: 1867: 1864: 1863: 1859: 1856: 1853: 1850: 1847: 1844: 1843: 1839: 1836: 1833: 1830: 1827: 1824: 1823: 1819: 1816: 1813: 1810: 1807: 1804: 1803: 1800: 1797: 1794: 1791: 1788: 1785: 1784: 1781: 1778: 1775: 1772: 1769: 1766: 1765: 1762: 1759: 1756: 1753: 1750: 1747: 1746: 1743: 1740: 1737: 1734: 1731: 1728: 1727: 1724: 1721: 1718: 1715: 1712: 1709: 1708: 1705: 1702: 1699: 1696: 1693: 1690: 1689: 1686: 1683: 1680: 1677: 1674: 1671: 1670: 1667: 1664: 1661: 1658: 1655: 1652: 1651: 1647: 1642: 1637: 1632: 1627: 1624: 1623: 1620: 1613: 1611: 1609: 1605: 1601: 1597: 1593: 1589: 1585: 1580: 1577: 1573: 1569: 1565: 1561: 1557: 1553: 1548: 1543: 1541: 1540: 1535: 1534:Deutsche Bank 1531: 1527: 1526: 1521: 1517: 1509: 1496: 1490: 1484: 1479: 1476: 1471: 1468: 1460: 1454: 1453: 1449: 1446: 1440: 1435:Galapagos NV 1434: 1428: 1422: 1416: 1413: 1407: 1401: 1395: 1389: 1383: 1378: 1375: 1369: 1363: 1362: 1361: 1358: 1357: 1347: 1345: 1343: 1338: 1336: 1331: 1329: 1323: 1321: 1316: 1314: 1310: 1305: 1303: 1299: 1295: 1291: 1287: 1282: 1279: 1275: 1270: 1267: 1259: 1257: 1255: 1249: 1247: 1243: 1239: 1235: 1231: 1226: 1224: 1222: 1217: 1213: 1209: 1201: 1197: 1193: 1189: 1186: 1182: 1178: 1175: 1171: 1167: 1166: 1165: 1162: 1160: 1156: 1151: 1149: 1145: 1140: 1136: 1135:(see below). 1134: 1130: 1126: 1113: 1107: 1103: 1098: 1091: 1089: 1087: 1086: 1079: 1077: 1073: 1069: 1064: 1062: 1058: 1054: 1050: 1046: 1040: 1038: 1034: 1025: 1023: 1019: 1018:emtricitabine 1015: 1011: 1007: 1003: 998: 996: 995: 990: 984: 982: 978: 973: 970: 965: 960: 958: 953: 948: 946: 945:emtricitabine 942: 938: 934: 933:emtricitabine 929: 927: 922: 920: 912: 910: 906: 904: 900: 896: 892: 888: 884: 880: 876: 871: 869: 865: 861: 856: 854: 850: 846: 842: 837: 835: 831: 827: 819: 817: 813: 811: 807: 801: 798: 794: 790: 789: 784: 781:when he read 780: 776: 772: 768: 764: 759: 757: 753: 749: 745: 741: 737: 732: 730: 726: 722: 721:Harold Varmus 718: 714: 710: 706: 702: 698: 694: 690: 686: 682: 678: 674: 664: 660: 650: 646: 641: 636: 630: 625: 623: 619: 617: 613: 608: 607:that decade. 606: 602: 598: 594: 589: 587: 583: 579: 575: 571: 567: 563: 559: 555: 551: 547: 543: 537: 507: 498: 494: 490: 484: 480: 475: 18,000 470: 464: 452: 449: 444: 432: 429: 424: 412: 409: 404: 392: 389: 384: 379:27.12 billion 378: 369: 365: 359: 356: 354: 351: 349: 346: 344: 341: 339: 336: 334: 331: 329: 326: 324: 321: 319: 316: 314: 311: 309: 306: 304: 301: 299: 296: 294: 291: 289: 286: 284: 281: 279: 276: 274: 271: 269: 266: 264: 261: 259: 256: 254: 251: 249: 246: 244: 241: 239: 236: 234: 231: 229: 226: 225: 223: 219: 212: 208: 205: 202: 198: 195: 191: 190: 188: 182: 178: 172: 168: 165: 161: 157: 153: 139: 135: 129: 128:Biotechnology 126: 124: 123:Pharmaceutics 121: 120: 118: 114: 107: 104: 101: 98: 95: 92: 90: 87: 85: 81: 78: 77: 75: 72: 67: 64: 61: 57: 50: 45: 41: 36: 30: 19: 7208:PDD Holdings 7178:Old Dominion 7088:Lam Research 7032: 6893:Baker Hughes 6474:Mallinckrodt 6359:Upsher-Smith 6190:Ortho-McNeil 6149: 5918:. Retrieved 5893:. Retrieved 5883: 5848: 5844: 5834: 5822:. Retrieved 5812: 5800:. Retrieved 5790: 5778:. Retrieved 5768: 5754:cite journal 5719: 5715: 5709: 5666: 5662: 5652: 5640:. Retrieved 5636: 5626: 5614:. Retrieved 5610: 5600: 5591: 5582: 5570:. Retrieved 5566: 5541:. Retrieved 5527: 5516: 5491:. Retrieved 5489:(4): 1093–94 5486: 5482: 5472: 5460:. Retrieved 5454: 5444: 5432:. Retrieved 5428: 5418: 5406:. Retrieved 5392: 5367:. Retrieved 5363: 5353: 5341:. Retrieved 5337: 5310:. Retrieved 5306: 5296: 5284:. Retrieved 5280: 5270: 5258:. Retrieved 5254: 5244: 5209: 5205: 5195: 5183:. Retrieved 5179: 5169: 5157:. Retrieved 5153: 5143: 5131:. Retrieved 5127: 5117: 5105:. Retrieved 5101: 5091: 5079:. Retrieved 5075: 5050:. Retrieved 5046: 5022: 5012: 5003: 4996:. Retrieved 4992: 4982: 4970:. Retrieved 4966: 4956: 4946:February 22, 4944:. Retrieved 4937:the original 4919: 4907:. Retrieved 4903: 4893: 4881:. Retrieved 4876: 4867: 4840: 4836: 4826: 4791: 4787: 4777: 4765:. Retrieved 4761: 4751: 4739:. Retrieved 4735: 4725: 4706: 4702: 4692: 4680:. Retrieved 4669: 4654: 4645: 4635: 4624: 4590:. Retrieved 4586:the original 4581: 4572: 4560:. Retrieved 4556: 4547: 4535:. Retrieved 4528:the original 4521: 4464: 4431: 4427: 4421: 4412:the original 4396: 4382: 4370:. Retrieved 4356: 4346: 4332: 4318: 4309: 4300: 4288:. Retrieved 4284: 4274: 4260: 4246: 4232: 4218: 4206:. Retrieved 4202: 4193: 4179: 4167:. Retrieved 4153: 4143: 4134: 4125: 4111: 4097: 4083: 4071:. Retrieved 4059: 4049: 4040: 4031: 4021:September 7, 4019:. Retrieved 4012: 4003: 3993:September 7, 3991:. Retrieved 3984: 3975: 3963:. Retrieved 3957: 3947: 3935:. Retrieved 3930: 3921: 3909:. Retrieved 3905:the original 3900: 3891: 3882:the original 3876: 3867: 3858: 3849: 3840: 3831: 3819:. Retrieved 3805: 3795: 3783:. Retrieved 3769: 3759: 3750:the original 3744: 3735: 3725:December 10, 3723:. Retrieved 3719: 3709: 3697:. Retrieved 3692: 3683: 3674: 3665: 3655:December 14, 3653:. Retrieved 3649: 3640: 3631: 3622: 3610:. Retrieved 3606:the original 3601: 3592: 3582:December 31, 3580:. Retrieved 3575: 3566: 3557: 3548: 3537: 3528: 3516:. Retrieved 3506: 3494:. Retrieved 3489: 3480: 3468:. Retrieved 3463: 3454: 3442:. Retrieved 3438:the original 3434:Today Health 3433: 3423: 3411:. Retrieved 3404: 3379:. Retrieved 3374: 3365: 3355:February 22, 3353:. Retrieved 3349:the original 3339: 3327:. Retrieved 3323:the original 3313: 3301:. Retrieved 3297:www.cnbc.com 3296: 3287: 3275:. Retrieved 3269: 3260: 3248:. Retrieved 3241: 3217:. Retrieved 3213:the original 3203: 3191:. Retrieved 3182: 3170:. Retrieved 3166:the original 3156: 3144:. Retrieved 3134: 3124:December 15, 3122:. Retrieved 3118:the original 3104: 3092:. Retrieved 3086: 3076: 3064:. Retrieved 3059: 3050: 3038:. Retrieved 3033: 3023: 3014: 3005: 2996: 2948: 2944: 2934: 2918: 2897:. Retrieved 2892: 2883: 2871:. Retrieved 2866: 2857: 2845:. Retrieved 2840: 2831: 2819:. Retrieved 2807: 2797: 2785:. 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