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Gordon M. Keller

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in 1979, and completed his postdoctoral fellowship with the Ontario Cancer Institute in 1983. He then began his career in Switzerland and Austria. In 1990, he moved to the United States. Initially, Keller was at the National Jewish Centre for Immunology and Respiratory Medicine in Denver, CO and
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Nostro MC, Sarangi F, Ogawa S, Holtzinger A, Corneo B, Li X, Micallef SJ, Park IH, Basford C, Wheeler MB, Daley GQ, Elefanty AG, Stanley EG, Keller G (2011).
287: 773: 788: 783: 361: 163: 115: 495:"Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells" 778: 753: 626:"T lymphocyte potential marks the emergence of definitive hematopoietic progenitors in human pluripotent stem cell differentiation cultures" 544:"Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages" 768: 312: 743: 409:
Choi K, Kennedy M, Kazarov A, Papadimitriou JC, Keller G (1998). "A common precursor for hematopoietic and endothelial cells".
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in New York City, NY. In 2007, Keller returned to Canada to assume his current role and established his laboratory at the
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Currently, the Keller group's research includes the differentiation of pluripotent stem cells to the
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Kennedy M, Awong G, Sturgeon CM, Ditadi A, LaMotte-Mohs R, Zúñiga-Pflücker JC, Keller G (2012).
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in Embryonic Stem Cell Biology (2013-2020). He serves on the Scientific Advisory Boards of the
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Craft AM, Ahmed N, Rockel JS, Baht GS, Alman BA, Kandel RA, Grigoriadis AE, Keller GM (2013).
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In 1997, Keller's team was the first to successfully isolate the developmentally significant
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and Stemgent, and is also a founding member and past president (2005-2006) of the
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for the development of iPSC-derived cells for clinical transplantation.
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and was raised on a farm. He completed his Bachelor of Science at the
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is a Canadian scientist recognized for his research on applying
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Han S, Dziedzic N, Gadue P, Keller GM, Gouon-Evans V (2011).
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Sturgeon CM, Ditadi A, Awong G, Kennedy M, Keller G (2014).
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differentiation. He is currently a Senior Scientist at the
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Centre for Commercialization of Regenerative Medicine
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Centre for Commercialization of Regenerative Medicine
283: 111: 103: 80: 62: 48: 40: 28: 21: 8: 398:"Honorary Doctor of Science - Gordon Keller" 288:International Society for Stem Cell Research 749:Academic staff of the University of Toronto 201:MaRS Centre/Toronto Medical Discovery Tower 18: 690: 641: 600: 559: 518: 469: 542:Kattman SJ, Huber TL, Keller GM (2006). 107:Stem cell biology, Developmental biology 303: 164:McEwen Centre for Regenerative Medicine 116:McEwen Centre for Regenerative Medicine 350:"Research Profile: Gordon Keller, PhD" 332: 330: 328: 326: 92:Ogawa-Yamanaka Stem Cell Prize (2019) 7: 311:Langelier, Julie (July 31, 2019). 14: 774:University of Saskatchewan alumni 789:21st-century Canadian biologists 784:20th-century Canadian scientists 338:"Lead Scientist: Gordon Keller" 197:Mount Sinai School of Medicine 35:Melville, Saskatchewan, Canada 16:Canadian biologist (born 1952) 1: 85:25 Transformational Canadians 779:University of Alberta alumni 754:Scientists from Saskatchewan 643:10.1016/j.celrep.2012.11.003 561:10.1016/j.devcel.2006.10.002 130:University of Alberta, Ph.D. 396:University of Saskatchewan 250:progenitors; as well as to 174:Keller was born in 1952 in 805: 348:University Health Network 186:. He completed his PhD in 184:University of Saskatchewan 57:University of Saskatchewan 134: 124:University Health Network 96: 162:and the director of the 156:Ontario Cancer Institute 128:Ontario Cancer Institute 769:Scientists from Toronto 744:Canada Research Chairs 278:Keller holds a Tier I 75:pluripotent stem cells 739:Stem cell researchers 423:10.1242/dev.125.4.725 280:Canada Research Chair 192:University of Alberta 160:University of Toronto 158:, a Professor at the 152:pluripotent stem cell 145:developmental biology 120:University of Toronto 89:Canada Research Chair 53:University of Alberta 23:Gordon Michael Keller 671:Nature Biotechnology 384:The Globe and Mail 229:embryonic stem cell 211:Scientific research 195:later moved to the 719:: Editorial Board" 602:10.1242/dev.087890 548:Developmental Cell 511:10.1242/dev.055236 595:(12): 2597–2610. 138: 137: 98:Scientific career 44:Canadian/American 796: 723: 722: 711: 705: 704: 694: 683:10.1038/nbt.2915 662: 656: 655: 645: 636:(6): 1722–1735. 621: 615: 614: 604: 580: 574: 573: 563: 539: 533: 532: 522: 490: 484: 483: 473: 462:10.1002/stem.576 441: 435: 434: 406: 400: 394: 388: 382: 376: 375: 373: 371: 366: 358: 352: 346: 340: 334: 321: 320: 308: 225:endothelial cell 141:Gordon M. Keller 19: 804: 803: 799: 798: 797: 795: 794: 793: 729: 728: 727: 726: 713: 712: 708: 664: 663: 659: 623: 622: 618: 582: 581: 577: 541: 540: 536: 492: 491: 487: 443: 442: 438: 408: 407: 403: 395: 391: 383: 379: 369: 367: 364: 360: 359: 355: 347: 343: 335: 324: 310: 309: 305: 300: 276: 213: 172: 126: 122: 118: 91: 87: 71:differentiation 55: 49:Alma mater 36: 33: 24: 17: 12: 11: 5: 802: 800: 792: 791: 786: 781: 776: 771: 766: 761: 756: 751: 746: 741: 731: 730: 725: 724: 706: 677:(6): 554–561. 657: 616: 575: 554:(5): 723–732. 534: 505:(5): 861–871. 485: 456:(2): 217–228. 436: 417:(4): 725–732. 401: 389: 377: 353: 341: 322: 302: 301: 299: 296: 275: 272: 256:cardiomyocytes 244:cholangiocytes 212: 209: 171: 168: 136: 135: 132: 131: 113: 109: 108: 105: 101: 100: 94: 93: 82: 78: 77: 64: 63:Known for 60: 59: 50: 46: 45: 42: 38: 37: 34: 30: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 801: 790: 787: 785: 782: 780: 777: 775: 772: 770: 767: 765: 762: 760: 759:Living people 757: 755: 752: 750: 747: 745: 742: 740: 737: 736: 734: 720: 718: 710: 707: 702: 698: 693: 688: 684: 680: 676: 672: 668: 661: 658: 653: 649: 644: 639: 635: 631: 627: 620: 617: 612: 608: 603: 598: 594: 590: 586: 579: 576: 571: 567: 562: 557: 553: 549: 545: 538: 535: 530: 526: 521: 516: 512: 508: 504: 500: 496: 489: 486: 481: 477: 472: 467: 463: 459: 455: 451: 447: 440: 437: 432: 428: 424: 420: 416: 412: 405: 402: 399: 393: 390: 387: 381: 378: 363: 357: 354: 351: 345: 342: 339: 333: 331: 329: 327: 323: 318: 317:gladstone.org 314: 307: 304: 297: 295: 293: 289: 285: 281: 273: 271: 269: 265: 264:T lymphocytes 261: 257: 253: 249: 245: 241: 237: 232: 230: 226: 222: 221:hematopoietic 218: 217:hemangioblast 210: 208: 206: 205:Lorenz Studer 202: 198: 193: 189: 185: 181: 177: 169: 167: 165: 161: 157: 153: 150: 146: 142: 133: 129: 125: 121: 117: 114: 110: 106: 102: 99: 95: 90: 86: 83: 79: 76: 72: 68: 65: 61: 58: 54: 51: 47: 43: 39: 32:November 1952 31: 27: 20: 716: 709: 674: 670: 660: 633: 630:Cell Reports 629: 619: 592: 588: 578: 551: 547: 537: 502: 498: 488: 453: 449: 439: 414: 410: 404: 392: 380: 368:. Retrieved 356: 344: 316: 306: 291: 277: 270:precursors. 260:chondrocytes 254:cell fates: 233: 231:technology. 227:fates—using 214: 180:Saskatchewan 173: 148: 147:findings to 140: 139: 112:Institutions 97: 66: 764:1952 births 717:Development 589:Development 499:Development 411:Development 370:14 December 292:Development 240:hepatocytes 41:Nationality 733:Categories 450:Stem Cells 298:References 252:mesodermal 248:pancreatic 236:endodermal 188:Immunology 238:lineage: 170:Biography 69:directed 701:24837661 652:23219550 611:23715552 570:17084363 529:21270052 480:21732480 176:Melville 149:in vitro 67:In vitro 692:4152856 520:3035090 471:3437666 431:9435292 274:Honours 268:myeloid 190:at the 699:  689:  650:  609:  568:  527:  517:  478:  468:  429:  104:Fields 81:Awards 365:(PDF) 697:PMID 648:PMID 607:PMID 566:PMID 525:PMID 476:PMID 427:PMID 372:2023 266:and 246:and 223:and 29:Born 687:PMC 679:doi 638:doi 597:doi 593:140 556:doi 515:PMC 507:doi 503:138 466:PMC 458:doi 419:doi 415:125 73:of 735:: 695:. 685:. 675:32 673:. 669:. 646:. 632:. 628:. 605:. 591:. 587:. 564:. 552:11 550:. 546:. 523:. 513:. 501:. 497:. 474:. 464:. 454:29 452:. 448:. 425:. 413:. 325:^ 315:. 294:. 262:, 258:, 242:, 178:, 166:. 721:. 715:" 703:. 681:: 654:. 640:: 634:2 613:. 599:: 572:. 558:: 531:. 509:: 482:. 460:: 433:. 421:: 374:. 319:.

Index

University of Alberta
University of Saskatchewan
differentiation
pluripotent stem cells
25 Transformational Canadians
Canada Research Chair
McEwen Centre for Regenerative Medicine
University of Toronto
University Health Network
Ontario Cancer Institute
developmental biology
pluripotent stem cell
Ontario Cancer Institute
University of Toronto
McEwen Centre for Regenerative Medicine
Melville
Saskatchewan
University of Saskatchewan
Immunology
University of Alberta
Mount Sinai School of Medicine
MaRS Centre/Toronto Medical Discovery Tower
Lorenz Studer
hemangioblast
hematopoietic
endothelial cell
embryonic stem cell
endodermal
hepatocytes
cholangiocytes

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