Knowledge (XXG)

Growth hormone 1

Source đź“ť

334: 1213:, an arrangement thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. 311: 1683: 208: 233: 1698: 1638: 1668: 1653: 1608: 599: 592: 585: 340: 239: 1593: 1578: 29: 1623: 2407: 1208:
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones that play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same
55: 1682: 1738: 1461:
Cattini PA, Yang X, Jin Y, Detillieux KA (2006). "Regulation of the human growth hormone gene family: possible role for Pit-1 in early stages of pituitary-specific expression and repression".
1697: 1637: 1667: 1731: 347: 246: 1747: 1652: 1724: 1607: 2476: 2385: 169: 892: 873: 2087: 2481: 2452: 2471: 1557: 1307: 1289: 2167: 1592: 333: 52: 1123: 1577: 1116: 310: 2122: 1374: 1276: 1255: 1910: 1691:: PHAGE DISPLAY DERIVED VARIANT OF HUMAN GROWTH HORMONE COMPLEXED WITH TWO COPIES OF THE EXTRACELLULAR DOMAIN OF ITS RECEPTOR 232: 207: 1272: 1498:
Wagner K, Hemminki K, Försti A (2007). "The GH1/IGF-1 axis polymorphisms and their impact on breast cancer development".
1251: 149: 1210: 2445: 346: 245: 1550: 339: 238: 1820: 1810: 1222: 937: 157: 1622: 1768: 918: 1800: 2027: 2438: 1925: 221: 2067: 1845: 2370: 2346: 1795: 1543: 2192: 1952: 1785: 136: 2341: 2127: 2007: 1790: 1227: 2187: 2052: 2077: 1987: 1967: 1900: 1865: 1855: 1825: 1760: 1706:: HUMAN GROWTH HORMONE AND EXTRACELLULAR DOMAIN OF ITS RECEPTOR: CRYSTAL STRUCTURE OF THE COMPLEX 1523: 1486: 1414: 181: 2247: 2132: 2072: 1957: 1875: 1870: 1835: 1099: 1078: 1074: 1070: 1044: 1023: 1019: 1015: 1011: 1007: 2326: 2321: 2304: 2294: 2252: 2117: 2107: 2062: 2017: 1977: 1972: 1942: 1885: 2336: 2197: 2157: 1815: 1515: 1478: 1449: 1406: 1356: 129: 45: 2422: 2360: 2355: 2037: 2032: 2227: 2222: 2217: 2212: 2042: 2012: 1947: 1507: 1470: 1439: 1398: 1346: 1338: 426: 357: 301: 256: 598: 591: 584: 1646:: THE CRYSTAL STRUCTURE OF AFFINITY-MATURED HUMAN GROWTH HORMONE AT 2 ANGSTROMS RESOLUTION 401: 177: 1327:"The human growth hormone gene family: structure and evolution of the chromosomal locus" 1805: 1757: 1393:
Binder G (2003). "Isolated growth hormone deficiency and the GH-1 gene: update 2002".
1351: 1326: 807: 802: 797: 792: 787: 782: 777: 772: 767: 762: 757: 752: 747: 742: 737: 732: 727: 722: 717: 701: 696: 691: 686: 681: 665: 660: 655: 650: 645: 640: 2465: 2418: 1716: 627: 1527: 1490: 1418: 28: 2289: 2022: 1840: 1676:: 1:1 COMPLEX OF HUMAN GROWTH HORMONE MUTANT G120R WITH ITS SOLUBLE BINDING PROTEIN 419: 198: 161: 185: 2309: 2267: 2262: 2257: 2242: 2147: 2142: 2002: 1962: 1890: 1830: 1312:
National Center for Biotechnology Information, U.S. National Library of Medicine
1294:
National Center for Biotechnology Information, U.S. National Library of Medicine
502: 2299: 2284: 2272: 2237: 2202: 2137: 2047: 1997: 1992: 1982: 1860: 1511: 318: 215: 165: 1342: 2314: 2279: 837: 748:
positive regulation of insulin-like growth factor receptor signaling pathway
562: 440: 385: 372: 284: 271: 173: 1519: 1482: 1453: 1410: 1360: 1163: 1158: 2112: 1850: 1444: 1427: 1147: 982: 963: 2207: 1195: 949: 904: 1661:: 1:2 COMPLEX OF HUMAN GROWTH HORMONE WITH ITS SOLUBLE BINDING PROTEIN 1474: 1402: 106: 102: 98: 94: 90: 86: 82: 78: 74: 2232: 1131: 859: 140:, GH, GH-N, GHN, IGHD1B, hGH-N, GHB5, Growth hormone 1, IGHD2, IGHD1A 2406: 1616:: THE XRAY STRUCTURE OF A GROWTH HORMONE-PROLACTIN RECEPTOR COMPLEX 1428:"Growth hormone regulation of sex-dependent liver gene expression" 822: 818: 2414: 1202: 153: 1720: 1539: 778:
positive regulation of tyrosine phosphorylation of STAT protein
607: 1535: 768:
positive regulation of receptor signaling pathway via JAK-STAT
763:
positive regulation of phosphatidylinositol 3-kinase signaling
773:
positive regulation of activation of Janus kinase activity
1926: 2088: 758:
positive regulation of peptidyl-tyrosine phosphorylation
409: 2426: 1911: 788:
positive regulation of glucose transmembrane transport
718:
growth hormone receptor signaling pathway via JAK-STAT
574: 2371: 1752: 753:
positive regulation of multicellular organism growth
2369: 2168: 2166: 2086: 1924: 1767: 1092: 1063: 1037: 1000: 1601:: STRUCTURAL PLASTICITY AT THE HGH:HGHBP INTERFACE 1268: 1266: 1264: 1247: 1245: 1243: 1821:Placental growth hormone (growth hormone variant) 356: 255: 1586:: HUMAN GROWTH HORMONE BOUND TO SINGLE RECEPTOR 733:positive regulation of receptor internalization 1273:GRCm38: Ensembl release 89: ENSMUSG00000020713 2446: 1732: 1551: 1325:Barsh GS, Seeburg PH, Gelinas RE (Aug 1983). 16:Hormone that regulates growth and development 8: 1252:GRCh38: Ensembl release 89: ENSG00000259384 2453: 2439: 1739: 1725: 1717: 1558: 1544: 1536: 833: 728:positive regulation of MAP kinase activity 623: 397: 296: 193: 63: 1443: 1350: 783:regulation of signaling receptor activity 743:growth hormone receptor signaling pathway 533:fetal liver hematopoietic progenitor cell 702:collagen-containing extracellular matrix 1573: 1239: 1916:Tooltip Growth hormone-binding protein 1769: 1748: 18: 361: 322: 317: 260: 219: 214: 7: 2403: 2401: 1375:"Entrez Gene: GH1 growth hormone 1" 2425:. You can help Knowledge (XXG) by 1089: 1060: 1034: 997: 973: 954: 928: 909: 883: 864: 579: 549:choroid plexus of fourth ventricle 497: 435: 414: 14: 2477:Hormones of the somatotropic axis 1198:that in humans is encoded by the 2405: 1696: 1681: 1666: 1651: 1636: 1621: 1606: 1591: 1576: 597: 590: 583: 345: 338: 332: 309: 244: 237: 231: 206: 27: 697:growth hormone receptor complex 661:growth hormone receptor binding 2482:Human chromosome 17 gene stubs 1861:Somatrogon (MOD-4023; hGH-CTP) 1426:Waxman DJ, O'Connor C (2007). 608:More reference expression data 563:More reference expression data 475:right hemisphere of cerebellum 1: 798:positive regulation of growth 541:epithelium of small intestine 330: 229: 2472:Genes on human chromosome 17 537:Epithelium of choroid plexus 1898:Antisense oligonucleotides: 1211:transcriptional orientation 793:response to nutrient levels 545:nucleus of stria terminalis 2498: 2400: 1124:Chr 11: 106.19 – 106.19 Mb 666:prolactin receptor binding 1571: 1512:10.1007/s10549-006-9411-9 1308:"Mouse PubMed Reference:" 1290:"Human PubMed Reference:" 1162: 1157: 1153: 1146: 1130: 1111: 1096: 1067: 1056: 1041: 1004: 993: 980: 976: 961: 957: 948: 935: 931: 916: 912: 903: 890: 886: 871: 867: 858: 843: 836: 832: 816: 626: 622: 605: 582: 573: 560: 509: 500: 483:Descending thoracic aorta 447: 438: 408: 400: 396: 379: 366: 329: 308: 299: 295: 278: 265: 228: 205: 196: 192: 147: 144: 134: 127: 122: 71: 66: 49: 44: 39: 35: 26: 21: 1811:Human placental lactogen 1500:Breast Cancer Res. Treat 1223:Placental growth hormone 1180:pituitary growth hormone 1117:Chr 17: 63.92 – 63.92 Mb 803:animal organ development 1397:. 58 Suppl 3 (3): 2–6. 2203:Examorelin (hexarelin) 1631:: HUMAN GROWTH HORMONE 1343:10.1093/nar/11.12.3939 656:growth factor activity 363:11 E1|11 68.89 cM 723:response to estradiol 467:right coronary artery 324:Chromosome 11 (mouse) 222:Chromosome 17 (human) 2258:Pralmorelin (GHRP-2) 1801:Eftansomatropin alfa 1445:10.1210/me.2006-0007 682:extracellular region 67:List of PDB id codes 40:Available structures 2300:Ibutamoren (MK-677) 2128:Modified GRF (1-29) 2028:Somatostatin (1-28) 2023:Somatostatin (GHIH) 1791:Bovine somatotropin 1228:Somatotropin family 808:signal transduction 687:extracellular space 487:canal of the cervix 2413:This article on a 1463:Neuroendocrinology 938:ENSMUSG00000020713 711:Biological process 675:Cellular component 634:Molecular function 521:anterior pituitary 479:right uterine tube 455:anterior pituitary 2434: 2433: 2395: 2394: 2377: 2350: 2174: 2094: 2068:Cyclosomatostatin 1932: 1908:Binding proteins: 1816:Lonapegsomatropin 1775: 1714: 1713: 1475:10.1159/000095522 1403:10.1159/000066476 1331:Nucleic Acids Res 1173: 1172: 1169: 1168: 1142: 1141: 1107: 1106: 1086: 1085: 1052: 1051: 1031: 1030: 989: 988: 970: 969: 944: 943: 925: 924: 899: 898: 880: 879: 828: 827: 646:metal ion binding 618: 617: 614: 613: 569: 568: 556: 555: 529:perirhinal cortex 525:entorhinal cortex 494: 493: 392: 391: 291: 290: 118: 117: 114: 113: 50:Ortholog search: 2489: 2455: 2448: 2441: 2409: 2402: 2375: 2373: 2348: 2172: 2170: 2092: 2090: 1930: 1928: 1917: 1913: 1846:Somatropin pegol 1773: 1771: 1754: 1750: 1741: 1734: 1727: 1718: 1700: 1685: 1670: 1655: 1640: 1625: 1610: 1595: 1580: 1560: 1553: 1546: 1537: 1531: 1494: 1457: 1447: 1422: 1379: 1378: 1371: 1365: 1364: 1354: 1322: 1316: 1315: 1304: 1298: 1297: 1286: 1280: 1270: 1259: 1249: 1178:, also known as 1176:Growth hormone 1 1155: 1154: 1126: 1119: 1102: 1090: 1081: 1061: 1057:RefSeq (protein) 1047: 1035: 1026: 998: 974: 955: 929: 910: 884: 865: 834: 641:hormone activity 624: 610: 601: 594: 587: 580: 565: 505: 503:Top expressed in 498: 443: 441:Top expressed in 436: 415: 398: 388: 375: 364: 349: 342: 336: 325: 313: 297: 287: 274: 263: 248: 241: 235: 224: 210: 194: 188: 139: 132: 109: 64: 58: 37: 36: 31: 19: 2497: 2496: 2492: 2491: 2490: 2488: 2487: 2486: 2462: 2461: 2460: 2459: 2398: 2396: 2391: 2374: 2365: 2171: 2162: 2091: 2082: 1929: 1920: 1915: 1796:Efpegsomatropin 1772: 1763: 1745: 1715: 1710: 1707: 1701: 1692: 1686: 1677: 1671: 1662: 1656: 1647: 1641: 1632: 1626: 1617: 1611: 1602: 1596: 1587: 1581: 1567: 1564: 1534: 1497: 1469:(3–4): 145–53. 1460: 1438:(11): 2613–29. 1432:Mol. Endocrinol 1425: 1392: 1388: 1386:Further reading 1383: 1382: 1373: 1372: 1368: 1337:(12): 3939–58. 1324: 1323: 1319: 1306: 1305: 1301: 1288: 1287: 1283: 1271: 1262: 1250: 1241: 1236: 1219: 1164:View/Edit Mouse 1159:View/Edit Human 1122: 1115: 1112:Location (UCSC) 1098: 1077: 1073: 1069: 1043: 1022: 1018: 1014: 1010: 1006: 919:ENSG00000259384 812: 738:bone maturation 706: 670: 651:protein binding 606: 596: 595: 589: 588: 561: 552: 547: 543: 539: 535: 531: 527: 523: 519: 515: 513:pituitary gland 501: 490: 485: 481: 477: 473: 469: 465: 461: 457: 453: 451:pituitary gland 439: 383: 370: 362: 352: 351: 350: 343: 323: 300:Gene location ( 282: 269: 261: 251: 250: 249: 242: 220: 197:Gene location ( 186:GH1 - orthologs 148: 135: 128: 73: 51: 17: 12: 11: 5: 2495: 2493: 2485: 2484: 2479: 2474: 2464: 2463: 2458: 2457: 2450: 2443: 2435: 2432: 2431: 2410: 2393: 2392: 2390: 2389: 2381: 2379: 2367: 2366: 2364: 2363: 2358: 2353: 2344: 2339: 2330: 2329: 2324: 2312: 2307: 2302: 2297: 2292: 2287: 2282: 2270: 2265: 2260: 2255: 2250: 2245: 2240: 2235: 2230: 2225: 2220: 2215: 2210: 2205: 2200: 2195: 2193:Cortistatin-14 2190: 2178: 2176: 2164: 2163: 2161: 2160: 2151: 2150: 2145: 2140: 2135: 2130: 2125: 2120: 2115: 2110: 2098: 2096: 2093:(somatocrinin) 2084: 2083: 2081: 2080: 2075: 2070: 2065: 2056: 2055: 2050: 2045: 2040: 2035: 2030: 2025: 2020: 2015: 2010: 2005: 2000: 1995: 1990: 1985: 1980: 1975: 1970: 1965: 1960: 1955: 1953:Cortistatin-14 1950: 1945: 1936: 1934: 1931:(somatostatin) 1922: 1921: 1919: 1918: 1904: 1903: 1894: 1893: 1888: 1879: 1878: 1873: 1868: 1863: 1858: 1853: 1848: 1843: 1838: 1833: 1828: 1823: 1818: 1813: 1808: 1806:Growth hormone 1803: 1798: 1793: 1788: 1786:Albusomatropin 1779: 1777: 1774:(somatotropin) 1765: 1764: 1746: 1744: 1743: 1736: 1729: 1721: 1712: 1711: 1709: 1708: 1702: 1695: 1693: 1687: 1680: 1678: 1672: 1665: 1663: 1657: 1650: 1648: 1642: 1635: 1633: 1627: 1620: 1618: 1612: 1605: 1603: 1597: 1590: 1588: 1582: 1575: 1572: 1569: 1568: 1565: 1563: 1562: 1555: 1548: 1540: 1533: 1532: 1495: 1458: 1423: 1389: 1387: 1384: 1381: 1380: 1366: 1317: 1299: 1281: 1260: 1238: 1237: 1235: 1232: 1231: 1230: 1225: 1218: 1215: 1184:growth hormone 1171: 1170: 1167: 1166: 1161: 1151: 1150: 1144: 1143: 1140: 1139: 1137: 1135: 1128: 1127: 1120: 1113: 1109: 1108: 1105: 1104: 1094: 1093: 1087: 1084: 1083: 1065: 1064: 1058: 1054: 1053: 1050: 1049: 1039: 1038: 1032: 1029: 1028: 1002: 1001: 995: 991: 990: 987: 986: 978: 977: 971: 968: 967: 959: 958: 952: 946: 945: 942: 941: 933: 932: 926: 923: 922: 914: 913: 907: 901: 900: 897: 896: 888: 887: 881: 878: 877: 869: 868: 862: 856: 855: 850: 845: 841: 840: 830: 829: 826: 825: 814: 813: 811: 810: 805: 800: 795: 790: 785: 780: 775: 770: 765: 760: 755: 750: 745: 740: 735: 730: 725: 720: 714: 712: 708: 707: 705: 704: 699: 694: 692:endosome lumen 689: 684: 678: 676: 672: 671: 669: 668: 663: 658: 653: 648: 643: 637: 635: 631: 630: 620: 619: 616: 615: 612: 611: 603: 602: 577: 571: 570: 567: 566: 558: 557: 554: 553: 551: 550: 546: 542: 538: 534: 530: 526: 522: 518: 514: 510: 507: 506: 495: 492: 491: 489: 488: 484: 480: 476: 472: 471:gastric mucosa 468: 464: 460: 456: 452: 448: 445: 444: 432: 431: 423: 412: 406: 405: 402:RNA expression 394: 393: 390: 389: 381: 377: 376: 368: 365: 360: 354: 353: 344: 337: 331: 327: 326: 321: 315: 314: 306: 305: 293: 292: 289: 288: 280: 276: 275: 267: 264: 259: 253: 252: 243: 236: 230: 226: 225: 218: 212: 211: 203: 202: 190: 189: 146: 142: 141: 133: 125: 124: 120: 119: 116: 115: 112: 111: 69: 68: 60: 59: 48: 42: 41: 33: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2494: 2483: 2480: 2478: 2475: 2473: 2470: 2469: 2467: 2456: 2451: 2449: 2444: 2442: 2437: 2436: 2430: 2428: 2424: 2420: 2419:chromosome 17 2416: 2411: 2408: 2404: 2399: 2387: 2383: 2382: 2380: 2378: 2376:(somatomedin) 2368: 2362: 2359: 2357: 2354: 2352: 2351:-LysÂł)-GHRP-6 2345: 2343: 2342:Cortistatin-8 2340: 2338: 2335: 2332: 2331: 2328: 2325: 2323: 2320: 2316: 2313: 2311: 2308: 2306: 2303: 2301: 2298: 2296: 2293: 2291: 2288: 2286: 2283: 2281: 2278: 2274: 2271: 2269: 2266: 2264: 2261: 2259: 2256: 2254: 2251: 2249: 2246: 2244: 2241: 2239: 2236: 2234: 2231: 2229: 2226: 2224: 2221: 2219: 2216: 2214: 2211: 2209: 2206: 2204: 2201: 2199: 2196: 2194: 2191: 2189: 2186: 2183: 2180: 2179: 2177: 2175: 2165: 2159: 2156: 2153: 2152: 2149: 2146: 2144: 2141: 2139: 2136: 2134: 2131: 2129: 2126: 2124: 2121: 2119: 2116: 2114: 2111: 2109: 2106: 2103: 2100: 2099: 2097: 2095: 2085: 2079: 2076: 2074: 2071: 2069: 2066: 2064: 2061: 2058: 2057: 2054: 2051: 2049: 2046: 2044: 2041: 2039: 2036: 2034: 2031: 2029: 2026: 2024: 2021: 2019: 2016: 2014: 2011: 2009: 2008:Pentetreotide 2006: 2004: 2001: 1999: 1996: 1994: 1991: 1989: 1986: 1984: 1981: 1979: 1976: 1974: 1971: 1969: 1966: 1964: 1961: 1959: 1956: 1954: 1951: 1949: 1946: 1944: 1941: 1938: 1937: 1935: 1933: 1923: 1914: 1909: 1906: 1905: 1902: 1899: 1896: 1895: 1892: 1889: 1887: 1884: 1881: 1880: 1877: 1874: 1872: 1869: 1867: 1864: 1862: 1859: 1857: 1854: 1852: 1849: 1847: 1844: 1842: 1839: 1837: 1834: 1832: 1829: 1827: 1824: 1822: 1819: 1817: 1814: 1812: 1809: 1807: 1804: 1802: 1799: 1797: 1794: 1792: 1789: 1787: 1784: 1781: 1780: 1778: 1776: 1766: 1762: 1759: 1756: 1742: 1737: 1735: 1730: 1728: 1723: 1722: 1719: 1705: 1699: 1694: 1690: 1684: 1679: 1675: 1669: 1664: 1660: 1654: 1649: 1645: 1639: 1634: 1630: 1624: 1619: 1615: 1609: 1604: 1600: 1594: 1589: 1585: 1579: 1574: 1570: 1561: 1556: 1554: 1549: 1547: 1542: 1541: 1538: 1529: 1525: 1521: 1517: 1513: 1509: 1506:(3): 233–48. 1505: 1501: 1496: 1492: 1488: 1484: 1480: 1476: 1472: 1468: 1464: 1459: 1455: 1451: 1446: 1441: 1437: 1433: 1429: 1424: 1420: 1416: 1412: 1408: 1404: 1400: 1396: 1391: 1390: 1385: 1376: 1370: 1367: 1362: 1358: 1353: 1348: 1344: 1340: 1336: 1332: 1328: 1321: 1318: 1313: 1309: 1303: 1300: 1295: 1291: 1285: 1282: 1278: 1274: 1269: 1267: 1265: 1261: 1257: 1253: 1248: 1246: 1244: 1240: 1233: 1229: 1226: 1224: 1221: 1220: 1216: 1214: 1212: 1206: 1204: 1201: 1197: 1193: 1189: 1185: 1182:or simply as 1181: 1177: 1165: 1160: 1156: 1152: 1149: 1145: 1138: 1136: 1133: 1129: 1125: 1121: 1118: 1114: 1110: 1103: 1101: 1095: 1091: 1088: 1082: 1080: 1076: 1072: 1066: 1062: 1059: 1055: 1048: 1046: 1040: 1036: 1033: 1027: 1025: 1021: 1017: 1013: 1009: 1003: 999: 996: 994:RefSeq (mRNA) 992: 985: 984: 979: 975: 972: 966: 965: 960: 956: 953: 951: 947: 940: 939: 934: 930: 927: 921: 920: 915: 911: 908: 906: 902: 895: 894: 889: 885: 882: 876: 875: 870: 866: 863: 861: 857: 854: 851: 849: 846: 842: 839: 835: 831: 824: 820: 815: 809: 806: 804: 801: 799: 796: 794: 791: 789: 786: 784: 781: 779: 776: 774: 771: 769: 766: 764: 761: 759: 756: 754: 751: 749: 746: 744: 741: 739: 736: 734: 731: 729: 726: 724: 721: 719: 716: 715: 713: 710: 709: 703: 700: 698: 695: 693: 690: 688: 685: 683: 680: 679: 677: 674: 673: 667: 664: 662: 659: 657: 654: 652: 649: 647: 644: 642: 639: 638: 636: 633: 632: 629: 628:Gene ontology 625: 621: 609: 604: 600: 593: 586: 581: 578: 576: 572: 564: 559: 548: 544: 540: 536: 532: 528: 524: 520: 516: 512: 511: 508: 504: 499: 496: 486: 482: 478: 474: 470: 466: 462: 458: 454: 450: 449: 446: 442: 437: 434: 433: 430: 428: 424: 422: 421: 417: 416: 413: 411: 407: 403: 399: 395: 387: 382: 378: 374: 369: 359: 355: 348: 341: 335: 328: 320: 316: 312: 307: 303: 298: 294: 286: 281: 277: 273: 268: 258: 254: 247: 240: 234: 227: 223: 217: 213: 209: 204: 200: 195: 191: 187: 183: 179: 175: 171: 167: 163: 159: 155: 151: 143: 138: 131: 126: 121: 110: 108: 104: 100: 96: 92: 88: 84: 80: 76: 70: 65: 62: 61: 57: 54: 47: 43: 38: 34: 30: 25: 20: 2427:expanding it 2412: 2397: 2334:Antagonists: 2333: 2318: 2290:Capromorelin 2277:Non-peptide: 2276: 2188:Alexamorelin 2184: 2181: 2155:Antagonists: 2154: 2104: 2101: 2060:Antagonists: 2059: 2053:Veldoreotide 1939: 1907: 1897: 1883:Antagonists: 1882: 1841:Somatotropin 1782: 1703: 1688: 1673: 1658: 1643: 1628: 1613: 1598: 1583: 1503: 1499: 1466: 1462: 1435: 1431: 1394: 1369: 1334: 1330: 1320: 1311: 1302: 1293: 1284: 1207: 1199: 1192:somatotropin 1191: 1187: 1183: 1179: 1175: 1174: 1097: 1068: 1042: 1005: 981: 962: 936: 917: 891: 872: 852: 847: 425: 418: 384:106,192,691 371:106,191,097 145:External IDs 72: 2310:Macimorelin 2268:Tabimorelin 2263:Relamorelin 2243:Lenomorelin 2148:Tesamorelin 2143:Somatorelin 2078:Satoreotide 2003:Pasireotide 1988:NNC 26-9100 1968:Ilatreotide 1963:Edotreotide 1901:Atesidorsen 1891:Pegvisomant 1866:Somavaratan 1856:Sometribove 1831:Somapacitan 1826:Somagrebove 1566:PDB gallery 463:granulocyte 283:63,918,839 270:63,917,200 123:Identifiers 2466:Categories 2285:Anamorelin 2273:Ulimorelin 2248:Livoletide 2238:Ipamorelin 2138:Sermorelin 2133:Rismorelin 2073:CYN-154806 2048:Vapreotide 1998:Octreotide 1993:Octreotate 1983:Lanreotide 1958:Depreotide 1876:Somidobove 1871:Somavubove 1836:Somatosalm 1761:modulators 1279:, May 2017 1258:, May 2017 1234:References 429:(ortholog) 166:HomoloGene 2417:on human 2327:LY-444711 2322:LY-426410 2319:Unsorted: 2315:SM-130686 2305:L-692,585 2295:CP-464709 2280:Adenosine 2253:LY-444711 2182:Agonists: 2173:(ghrelin) 2118:Dumorelin 2108:ALRN-5281 2102:Agonists: 2063:BIM-23056 2018:Seglitide 1978:L-817,818 1973:L-803,087 1943:BIM-23052 1940:Agonists: 1886:G120K-hGH 1783:Agonists: 1758:signaling 1395:Horm. Res 1100:NP_032143 1079:NP_072054 1075:NP_072053 1071:NP_000506 1045:NM_008117 1024:NM_022562 1020:NM_022561 1016:NM_022560 1012:NM_022559 1008:NM_000515 838:Orthologs 174:GeneCards 2388:instead. 2337:A-778193 2198:EP-51216 2185:Peptide: 2158:MZ-5-156 2113:CJC-1295 2105:Peptide: 1851:Somatrem 1528:13544290 1520:17082888 1491:34757447 1483:17047377 1454:16543404 1419:34602772 1411:12435888 1275:– 1254:– 1217:See also 1148:Wikidata 817:Sources: 459:testicle 2361:YIL-781 2356:JMV2959 2208:Ghrelin 2038:SRIF-28 2033:SRIF-14 1361:6306568 1277:Ensembl 1256:Ensembl 1196:protein 1194:, is a 950:UniProt 905:Ensembl 844:Species 823:QuickGO 404:pattern 262:17q23.3 130:Aliases 2233:GHRP-6 2228:GHRP-5 2223:GHRP-4 2218:GHRP-3 2213:GHRP-1 2043:TT-232 2013:RC-160 1948:CH-275 1526:  1518:  1489:  1481:  1452:  1417:  1409:  1359:  1352:326017 1349:  1134:search 1132:PubMed 983:P06880 964:P01241 860:Entrez 575:BioGPS 517:morula 170:128036 154:139250 2421:is a 2372:IGF-1 1753:IGF-1 1524:S2CID 1487:S2CID 1415:S2CID 893:14599 853:Mouse 848:Human 819:Amigo 427:Mouse 420:Human 367:Start 302:Mouse 266:Start 199:Human 162:95707 2423:stub 2415:gene 2386:here 2384:See 2123:GHRH 2089:GHRH 1927:GHIH 1912:GHBP 1755:axis 1704:3hhr 1689:1kf9 1674:1hwh 1659:1hwg 1644:1huw 1629:1hgu 1614:1bp3 1599:1axi 1584:1a22 1516:PMID 1479:PMID 1450:PMID 1407:PMID 1357:PMID 1203:gene 874:2688 410:Bgee 358:Band 319:Chr. 257:Band 216:Chr. 150:OMIM 107:1HWH 103:1BP3 99:1HWG 95:1KF9 91:3HHR 87:1HGU 83:1A22 79:1HUW 75:1AXI 56:RCSB 53:PDBe 2169:GHS 1508:doi 1504:104 1471:doi 1440:doi 1399:doi 1347:PMC 1339:doi 1200:GH1 1190:) 380:End 279:End 182:OMA 178:GH1 158:MGI 137:GH1 46:PDB 22:GH1 2468:: 2317:; 2275:; 1770:GH 1749:GH 1522:. 1514:. 1502:. 1485:. 1477:. 1467:83 1465:. 1448:. 1436:20 1434:. 1430:. 1413:. 1405:. 1355:. 1345:. 1335:11 1333:. 1329:. 1310:. 1292:. 1263:^ 1242:^ 1205:. 1188:GH 821:/ 386:bp 373:bp 285:bp 272:bp 180:; 176:: 172:; 168:: 164:; 160:: 156:; 152:: 105:, 101:, 97:, 93:, 89:, 85:, 81:, 77:, 2454:e 2447:t 2440:v 2429:. 2349:D 2347:( 1751:/ 1740:e 1733:t 1726:v 1559:e 1552:t 1545:v 1530:. 1510:: 1493:. 1473:: 1456:. 1442:: 1421:. 1401:: 1377:. 1363:. 1341:: 1314:. 1296:. 1186:( 304:) 201:) 184::

Index


PDB
PDBe
RCSB
1AXI
1HUW
1A22
1HGU
3HHR
1KF9
1HWG
1BP3
1HWH
Aliases
GH1
OMIM
139250
MGI
95707
HomoloGene
128036
GeneCards
GH1
OMA
GH1 - orthologs
Human
Chromosome 17 (human)
Chr.
Chromosome 17 (human)
Chromosome 17 (human)

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

↑