258:
235:
132:
157:
523:
516:
509:
264:
163:
40:
4687:
2455:
3482:
2448:
2441:
3514:
3356:
271:
170:
1973:
2464:
1061:
93:
2507:
1042:
2952:
1959:
1787:
4207:
3459:
3095:
3003:
2900:
1920:
1915:
2614:
2570:
3507:
3417:
1949:
3737:
2497:
4717:
4707:
2373:
2185:
1944:
3706:
2167:
3396:
3319:
1797:α can activate only one adenylyl cyclase enzyme, amplification of the signal occurs because one receptor can activate multiple copies of G
257:
3500:
3439:
1756:
1540:
1533:
4406:
2848:
234:
2978:
3351:
4297:
2154:
2133:
1879:
4292:
3407:
2609:
2585:
2565:
2019:
2015:
156:
131:
4562:
3214:
2150:
1747:
and to Gβγ to form the inactive G protein trimer. When the receptor binds an activating ligand outside the cell (such as a
4314:
3166:
2619:
2203:
Ellis C, Nature
Reviews Drug Discovery GPCR Questionnaire Participants (July 2004). "The state of GPCR research in 2004".
4677:
2129:
1731:. GPCRs function as part of a three-component system of receptor-transducer-effector. The transducer in this system is a
4362:
3679:
3372:
3347:
3338:
3200:
2853:
2012:
73:
4284:
2480:
3231:
270:
169:
4722:
2075:
1902:
1895:
1888:
1728:
4547:
4663:
4650:
4637:
4624:
4611:
4598:
4585:
4343:
3884:
3782:
3607:
3603:
3580:
3553:
3540:
3527:
2028:
1884:
263:
162:
4557:
4511:
4454:
3898:
3593:
3558:
3531:
3454:
3041:
2544:
2526:
2406:
2396:
2080:
1732:
1714:
1616:
1106:
81:
4459:
4268:
4231:
3570:
3247:
2957:
2927:
2912:
2875:
2070:
1087:
3998:
3638:
2535:
2105:
2058:
2024:
1861:
1854:
1760:
1674:
1626:
4480:
4399:
4128:
4036:
3328:
3139:
2907:
2035:
1978:
1964:
1763:
binding to Gα, which drives dissociation of GTP-bound Gα from Gβγ. In particular, GTP-bound, activated G
1744:
145:
4552:
2731:
2048:
1935:
1928:
1740:
1508:
1504:
1484:
1480:
1411:
1407:
1403:
1391:
1387:
1383:
1379:
60:
4712:
4516:
4333:
3310:
3183:
1999:
1910:
1724:
1476:
1442:
1438:
1434:
1430:
1359:
1355:
1351:
1341:
1337:
1333:
1329:
1305:
1301:
1297:
1259:
1255:
1228:
1224:
1220:
1210:
1206:
1202:
1198:
1645:α is the founding member of one of the four families of heterotrimeric G proteins, defined by the
1516:
1512:
1500:
1496:
1492:
1488:
1415:
1399:
1395:
1375:
4449:
4348:
3914:
3492:
2716:
2681:
2402:
2346:
2280:
2228:
1850:
1694:
105:
2433:
1472:
1468:
1464:
1460:
1456:
1446:
1371:
1367:
1363:
1325:
1293:
1289:
1285:
1281:
1271:
1267:
1263:
1240:
1236:
1232:
1194:
3588:
2604:
2560:
2413:
2369:
2338:
2272:
2220:
2043:
1954:
1809:α-bound adenylyl cyclase enzyme can generate substantial cAMP to activate many copies of PKA.
53:
4495:
4490:
4464:
4392:
3978:
3924:
3772:
3762:
3716:
2575:
2553:
2328:
2320:
2264:
2212:
2100:
2095:
2090:
2085:
2007:
1779:
1772:
1768:
1752:
1666:
1654:
1630:
522:
515:
508:
350:
281:
225:
180:
3791:
3272:
2813:
4542:
4526:
4439:
4325:
4214:
4028:
3728:
3548:
3295:
3290:
3051:
3046:
3022:
3017:
2983:
2880:
2808:
2632:
1646:
325:
101:
2392:
2268:
64:, AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, POH, SCG6, SgVI, GNAS complex locus, PITA3
4691:
4580:
4521:
3648:
2994:
2333:
2308:
1845:
1839:
1832:
1825:
976:
971:
966:
961:
956:
951:
946:
941:
936:
931:
926:
921:
916:
911:
906:
901:
896:
891:
886:
881:
876:
871:
866:
861:
856:
851:
846:
841:
836:
831:
826:
821:
816:
811:
806:
801:
796:
791:
786:
781:
776:
771:
766:
761:
756:
740:
735:
730:
725:
720:
715:
710:
705:
700:
695:
690:
685:
680:
675:
670:
665:
660:
644:
639:
634:
629:
624:
619:
614:
609:
604:
599:
594:
589:
579:
574:
569:
564:
39:
4701:
4485:
4444:
4192:
3802:
3073:
3012:
2885:
2422:
1869:
551:
2364:
Purves D, Augustine GJ, Fitzpatrick D, Hall WC, LaMantia AS, White LE, eds. (2007).
2350:
2284:
2232:
4434:
4177:
4150:
4079:
4072:
4055:
4050:
4024:
3029:
2867:
343:
122:
85:
109:
4658:
4593:
4429:
4273:
2932:
2502:
2190:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2172:
National Center for
Biotechnology Information, U.S. National Library of Medicine
4686:
426:
4258:
3947:
3122:
2917:
2594:
2426:(Guanine nucleotide-binding protein G(s) subunit alpha isoforms short) at the
1775:
242:
139:
89:
3444:
4632:
4606:
3964:
3523:
3386:
2599:
2517:
1689:, named for its predominant expression in the olfactory system. In humans, G
1006:
584:
486:
364:
309:
296:
208:
195:
97:
2255:
Gilman AG (1987). "G proteins: transducers of receptor-generated signals".
2224:
2342:
2276:
1580:
1575:
1925:
1564:
1175:
1171:
1167:
1163:
1144:
1140:
1136:
1132:
972:
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
797:
adenylate cyclase-activating G protein-coupled receptor signaling pathway
4369:
4338:
4116:
4111:
3870:
3860:
3835:
3830:
3565:
3464:
3188:
3034:
2427:
2417:
2324:
1802:
1748:
1118:
1073:
1739:α, and a complex of two tightly linked proteins called Gβ and Gγ in a
4645:
4415:
4246:
3888:
3865:
3855:
3825:
3820:
3815:
3810:
3767:
3757:
3752:
3747:
3742:
3711:
3699:
3694:
3689:
3684:
3672:
3667:
3662:
3611:
3469:
3257:
3252:
2962:
1638:
1548:
1028:
2216:
1780:
cAMP-dependent protein kinase (also called
Protein Kinase A or PKA)
17:
4619:
4302:
4241:
4224:
4219:
4067:
4045:
4011:
4006:
3991:
3969:
3957:
3952:
3942:
3937:
3932:
3657:
3633:
3267:
3262:
3224:
3209:
3176:
3171:
3132:
3127:
3115:
3110:
3105:
3100:
3088:
3066:
3061:
3056:
2833:
2828:
2823:
2818:
2778:
2773:
2711:
2706:
2701:
2696:
2671:
2666:
2661:
2656:
2651:
2646:
2641:
2053:
837:
adenylate cyclase-activating adrenergic receptor signaling pathway
991:
987:
4307:
4263:
4251:
4236:
4202:
4197:
4182:
4165:
4160:
4155:
4143:
4138:
4133:
4123:
4099:
4094:
4089:
4084:
3986:
3449:
3434:
3219:
3159:
3154:
3149:
3144:
3083:
3078:
2922:
2895:
2890:
2803:
2798:
2793:
2788:
2783:
2760:
2755:
2750:
2745:
2740:
2691:
2686:
2676:
1994:
1990:
1986:
1982:
1873:
1702:
792:
adenylate cyclase-activating dopamine receptor signaling pathway
77:
4388:
3496:
2437:
531:
4357:
4353:
3483:
deficiencies of intracellular signaling peptides and proteins
2412:
Overview of all the structural information available in the
1685:. The Gs-family has only two members: the other member is G
4384:
2309:"Nobel Lecture: Signal transduction: Evolution of an idea"
333:
2368:(4th ed.). New York: W. H. Freeman. p. 155.
4675:
498:
1817:
The G protein-coupled receptors that couple to the G
1801:
while that receptor remains bound to its activating
1743:. When not stimulated by a receptor, Gα is bound to
1735:, composed of three subunits: a Gα protein such as G
762:
negative regulation of multicellular organism growth
4571:
4535:
4504:
4473:
4422:
4323:
4282:
4022:
3896:
3883:
3848:
3800:
3781:
3727:
3647:
3626:
3619:
3602:
3579:
3539:
3427:
3406:
3385:
3365:
3337:
3318:
3308:
3283:
3240:
3199:
3002:
2992:
2971:
2945:
2866:
2584:
2534:
2525:
2516:
2490:
2471:
1429:
1324:
1254:
1193:
3357:Sh2 domain-containing protein tyrosine phosphatase
2146:
2144:
2142:
2125:
2123:
2121:
1641:that functions as a cellular signaling protein. G
625:corticotropin-releasing hormone receptor 1 binding
937:positive regulation of osteoblast differentiation
902:positive regulation of osteoclast differentiation
777:positive regulation of cold-induced thermogenesis
280:
179:
1974:Luteinizing hormone/choriogonadotropin receptor
2151:GRCm38: Ensembl release 89: ENSMUSG00000027523
822:positive regulation of cAMP-mediated signaling
4400:
3508:
2465:Intracellular signaling peptides and proteins
2449:
2302:
2300:
2298:
2296:
2294:
2250:
2248:
2246:
2244:
2242:
832:cellular response to prostaglandin E stimulus
8:
877:G protein-coupled receptor signaling pathway
575:G-protein beta/gamma-subunit complex binding
2130:GRCh38: Ensembl release 89: ENSG00000087460
912:regulation of parathyroid hormone secretion
787:cellular response to catecholamine stimulus
615:insulin-like growth factor receptor binding
4407:
4393:
4385:
3893:
3623:
3616:
3515:
3501:
3493:
3352:Receptor-like protein tyrosine phosphatase
3315:
2999:
2531:
2522:
2456:
2442:
2434:
1727:in response to activation of cell surface
1426:
1321:
1251:
1190:
1002:
547:
321:
220:
117:
2953:Cyclin-dependent kinase inhibitor protein
2405:at the U.S. National Library of Medicine
2395:at the U.S. National Library of Medicine
2332:
1960:Growth-hormone-releasing hormone receptor
977:positive regulation of catalytic activity
3460:Phosphatidylethanolamine binding protein
3096:Interleukin-1 receptor associated kinase
2508:Ca2+/calmodulin-dependent protein kinase
1921:Corticotropin-releasing hormone receptor
1916:Calcitonin gene-related peptide receptor
952:embryonic cranial skeleton morphogenesis
827:activation of adenylate cyclase activity
4682:
2117:
1950:Gastric inhibitory polypeptide receptor
947:sensory perception of chemical stimulus
27:Mammalian protein found in Homo sapiens
3215:Focal adhesion protein-tyrosine kinase
2498:Intracellular calcium-sensing proteins
847:positive regulation of GTPase activity
812:cellular response to glucagon stimulus
29:
1945:Follicle-stimulating hormone receptor
635:ionotropic glutamate receptor binding
285:
246:
241:
184:
143:
138:
7:
1870:Adrenocorticotropic hormone receptor
1755:), the activated receptor acts as a
610:adenylate cyclase activator activity
2269:10.1146/annurev.bi.56.070187.003151
1786:α acting through PKA are described
1729:G protein-coupled receptors (GPCRs)
3440:Signal transducing adaptor protein
2615:3',5'-cyclic-GMP phosphodiesterase
2571:3',5'-cyclic-AMP phosphodiesterase
1757:guanine nucleotide exchange factor
1154:
1123:
1097:
1078:
1052:
1033:
645:G protein-coupled receptor binding
630:beta-2 adrenergic receptor binding
503:
465:central gray substance of midbrain
421:
359:
338:
25:
3435:Activating transcription factor 6
2849:G protein-coupled receptor kinase
2054:Trace amine-associated receptor 1
922:post-embryonic body morphogenesis
882:regulation of signal transduction
391:lateral nuclear group of thalamus
4685:
2979:Phosphoinositide phospholipase C
1759:to promote GDP release from and
1725:intracellular signaling pathways
967:embryonic hindlimb morphogenesis
957:energy reserve metabolic process
711:heterotrimeric G-protein complex
521:
514:
507:
445:dorsomedial hypothalamic nucleus
269:
262:
256:
233:
168:
161:
155:
130:
38:
1985:, MC2R (a.k.a. ACTH receptor),
1880:Arginine vasopressin receptor 2
807:regulation of insulin secretion
782:hair follicle placode formation
767:response to parathyroid hormone
716:intrinsic component of membrane
666:perinuclear region of cytoplasm
620:mu-type opioid receptor binding
3418:GTP-binding protein regulators
3408:GTP-binding protein regulators
2205:Nature Reviews. Drug Discovery
1778:, which in turn activates the
532:More reference expression data
487:More reference expression data
1:
3167:Rho-associated protein kinase
2257:Annual Review of Biochemistry
2013:Parathyroid hormone receptors
897:multicellular organism growth
254:
153:
4718:Peripheral membrane proteins
4708:Genes on human chromosome 20
3373:Dual-specificity phosphatase
3348:protein tyrosine phosphatase
2854:AMP-activated protein kinase
696:trans-Golgi network membrane
640:D1 dopamine receptor binding
4285:Protein-synthesizing GTPase
3397:apoptosis signaling pathway
887:skeletal system development
842:sensory perception of smell
4739:
2076:G protein-coupled receptor
1712:
917:post-embryonic development
585:signal transducer activity
437:superior cervical ganglion
4563:Michaelis–Menten kinetics
4344:Guanylate-binding protein
3528:acid anhydride hydrolases
3478:
3241:Serine/threonine/tyrosine
2844:
2727:
2628:
2186:"Mouse PubMed Reference:"
2168:"Human PubMed Reference:"
1821:family proteins include:
1793:Although each GTP-bound G
1719:The general function of G
1579:
1574:
1570:
1563:
1547:
1541:Chr 2: 174.13 – 174.19 Mb
1528:
1453:
1348:
1317:
1278:
1217:
1186:
1161:
1157:
1130:
1126:
1117:
1104:
1100:
1085:
1081:
1072:
1059:
1055:
1040:
1036:
1027:
1012:
1005:
1001:
985:
907:endochondral ossification
605:guanyl nucleotide binding
550:
546:
529:
506:
497:
484:
433:
424:
371:
362:
332:
324:
320:
303:
290:
253:
232:
223:
219:
202:
189:
152:
129:
120:
116:
71:
68:
58:
51:
46:
37:
32:
4455:Diffusion-limited enzyme
3899:Heterotrimeric G protein
3594:Phosphoadenylylsulfatase
3455:Olfactory marker protein
3042:Glycogen synthase kinase
2545:Heterotrimeric G protein
2407:Medical Subject Headings
2397:Medical Subject Headings
2081:Heterotrimeric G protein
1733:heterotrimeric G protein
1715:Heterotrimeric G protein
1617:heterotrimeric G protein
1534:Chr 20: 58.84 – 58.91 Mb
3571:Thiamine-triphosphatase
3248:Dual-specificity kinase
2958:Cyclin-dependent kinase
2071:Second messenger system
1782:. Cellular effects of G
857:renal water homeostasis
817:intracellular transport
2106:G12/G13 alpha subunits
2059:Vasopressin receptor 2
2025:Prostaglandin receptor
1885:β-adrenergic receptors
1846:serotonergic receptors
1627:cAMP-dependent pathway
1615:) is a subunit of the
741:apical plasma membrane
407:superior frontal gyrus
4548:Eadie–Hofstee diagram
4481:Allosteric regulation
4326:Polymerization motors
4037:Rho family of GTPases
3329:Protein phosphatase 2
3140:p21-activated kinases
1979:Melanocortin receptor
932:cartilage development
721:extracellular exosome
146:Chromosome 20 (human)
4558:Lineweaver–Burk plot
2732:G beta-gamma complex
2049:Thyrotropin receptor
1701:α is encoded by the
1693:α is encoded by the
1625:that stimulates the
867:platelet aggregation
852:developmental growth
671:extracellular region
287:2 H4|2 97.89 cM
248:Chromosome 2 (mouse)
4334:dynamin superfamily
3311:protein phosphatase
3184:Ribosomal s6 kinase
2403:GNAS+protein,+human
2211:(7): 575, 577–626.
2000:Olfactory receptors
1911:Calcitonin receptor
1649:they contain: the G
872:signal transduction
681:cytoplasmic vesicle
4517:Enzyme superfamily
4450:Enzyme promiscuity
2481:MAP kinase pathway
2325:10.1007/bf01207453
2313:Bioscience Reports
2307:Rodbell M (1995).
1851:Adenosine receptor
1695:GNAS complex locus
1107:ENSMUSG00000027523
942:tissue homeostasis
892:genetic imprinting
750:Biological process
654:Cellular component
570:nucleotide binding
565:molecular function
558:Molecular function
395:anterior pituitary
4723:Medical mnemonics
4673:
4672:
4382:
4381:
4378:
4377:
3879:
3878:
3844:
3843:
3589:Adenylylsulfatase
3490:
3489:
3445:I-kappa B protein
3381:
3380:
3304:
3303:
2941:
2940:
2862:
2861:
2605:Guanylate cyclase
2561:Adenylate cyclase
2375:978-0-87893-697-7
2044:Secretin receptor
2008:olfactory neurons
1955:Glucagon receptor
1590:
1589:
1586:
1585:
1559:
1558:
1524:
1523:
1423:
1422:
1313:
1312:
1248:
1247:
1182:
1181:
1151:
1150:
1113:
1112:
1094:
1093:
1068:
1067:
1049:
1048:
997:
996:
772:protein secretion
676:transport vesicle
590:metal ion binding
542:
541:
538:
537:
493:
492:
480:
479:
449:perirhinal cortex
441:entorhinal cortex
418:
417:
403:entorhinal cortex
379:postcentral gyrus
316:
315:
215:
214:
16:(Redirected from
4730:
4690:
4689:
4681:
4553:Hanes–Woolf plot
4496:Enzyme activator
4491:Enzyme inhibitor
4465:Enzyme catalysis
4409:
4402:
4395:
4386:
3894:
3624:
3617:
3517:
3510:
3503:
3494:
3320:Serine/threonine
3316:
3004:Serine/threonine
3000:
2620:Protein kinase G
2576:Protein kinase A
2532:
2523:
2458:
2451:
2444:
2435:
2380:
2379:
2361:
2355:
2354:
2336:
2304:
2289:
2288:
2252:
2237:
2236:
2200:
2194:
2193:
2182:
2176:
2175:
2164:
2158:
2148:
2137:
2127:
2101:Gq alpha subunit
2096:Gi alpha subunit
2091:Protein kinase A
2086:Adenylyl cyclase
1773:second messenger
1769:adenylyl cyclase
1753:neurotransmitter
1631:adenylyl cyclase
1572:
1571:
1543:
1536:
1519:
1427:
1418:
1322:
1318:RefSeq (protein)
1308:
1252:
1243:
1191:
1155:
1124:
1098:
1079:
1053:
1034:
1003:
962:skin development
862:bone development
757:female pregnancy
548:
534:
525:
518:
511:
504:
489:
429:
427:Top expressed in
422:
399:Brodmann area 10
383:Brodmann area 46
367:
365:Top expressed in
360:
339:
322:
312:
299:
288:
273:
266:
260:
249:
237:
221:
211:
198:
187:
172:
165:
159:
148:
134:
118:
112:
110:GNAS - orthologs
63:
56:
42:
30:
21:
4738:
4737:
4733:
4732:
4731:
4729:
4728:
4727:
4698:
4697:
4696:
4684:
4676:
4674:
4669:
4581:Oxidoreductases
4567:
4543:Enzyme kinetics
4531:
4527:List of enzymes
4500:
4469:
4440:Catalytic triad
4418:
4413:
4383:
4374:
4319:
4278:
4029:Ras superfamily
4018:
4002:
3982:
3928:
3918:
3910:
3875:
3840:
3796:
3777:
3723:
3680:Plasma membrane
3643:
3598:
3575:
3549:Pyrophosphatase
3535:
3521:
3491:
3486:
3474:
3423:
3402:
3377:
3361:
3333:
3300:
3291:Arginine kinase
3279:
3236:
3195:
2988:
2984:Phospholipase C
2967:
2937:
2858:
2840:
2770:
2737:
2723:
2638:
2633:G alpha subunit
2624:
2580:
2512:
2486:
2467:
2462:
2389:
2384:
2383:
2376:
2363:
2362:
2358:
2306:
2305:
2292:
2254:
2253:
2240:
2217:10.1038/nrd1458
2202:
2201:
2197:
2184:
2183:
2179:
2166:
2165:
2161:
2149:
2140:
2128:
2119:
2114:
2067:
2039:
2032:
2005:
1968:
1939:
1932:
1906:
1899:
1892:
1865:
1858:
1843:
1836:
1829:
1820:
1815:
1808:
1800:
1796:
1785:
1771:to produce the
1766:
1738:
1723:is to activate
1722:
1717:
1711:
1700:
1692:
1688:
1682:
1678:
1670:
1662:
1658:
1652:
1644:
1636:
1623:
1612:
1605:
1597:
1581:View/Edit Mouse
1576:View/Edit Human
1539:
1532:
1529:Location (UCSC)
1515:
1511:
1507:
1503:
1499:
1495:
1491:
1487:
1483:
1479:
1475:
1471:
1467:
1463:
1459:
1455:
1449:
1445:
1441:
1437:
1433:
1414:
1410:
1406:
1402:
1398:
1394:
1390:
1386:
1382:
1378:
1374:
1370:
1366:
1362:
1358:
1354:
1350:
1344:
1340:
1336:
1332:
1328:
1304:
1300:
1296:
1292:
1288:
1284:
1280:
1274:
1270:
1266:
1262:
1258:
1239:
1235:
1231:
1227:
1223:
1219:
1213:
1209:
1205:
1201:
1197:
1174:
1170:
1166:
1143:
1139:
1135:
1088:ENSG00000087460
981:
927:DNA methylation
745:
731:cell projection
706:plasma membrane
649:
600:GTPase activity
595:protein binding
530:
520:
519:
513:
512:
485:
476:
471:
469:median eminence
467:
463:
459:
455:
453:pituitary gland
451:
447:
443:
439:
425:
414:
409:
405:
401:
397:
393:
389:
387:pituitary gland
385:
381:
377:
363:
307:
294:
286:
276:
275:
274:
267:
247:
224:Gene location (
206:
193:
185:
175:
174:
173:
166:
144:
121:Gene location (
72:
59:
52:
28:
23:
22:
15:
12:
11:
5:
4736:
4734:
4726:
4725:
4720:
4715:
4710:
4700:
4699:
4695:
4694:
4671:
4670:
4668:
4667:
4654:
4641:
4628:
4615:
4602:
4589:
4575:
4573:
4569:
4568:
4566:
4565:
4560:
4555:
4550:
4545:
4539:
4537:
4533:
4532:
4530:
4529:
4524:
4519:
4514:
4508:
4506:
4505:Classification
4502:
4501:
4499:
4498:
4493:
4488:
4483:
4477:
4475:
4471:
4470:
4468:
4467:
4462:
4457:
4452:
4447:
4442:
4437:
4432:
4426:
4424:
4420:
4419:
4414:
4412:
4411:
4404:
4397:
4389:
4380:
4379:
4376:
4375:
4373:
4372:
4367:
4366:
4365:
4360:
4351:
4346:
4341:
4330:
4328:
4321:
4320:
4318:
4317:
4312:
4311:
4310:
4305:
4300:
4289:
4287:
4280:
4279:
4277:
4276:
4271:
4266:
4261:
4256:
4255:
4254:
4249:
4244:
4239:
4229:
4228:
4227:
4222:
4212:
4211:
4210:
4205:
4200:
4188:
4187:
4186:
4185:
4180:
4170:
4169:
4168:
4163:
4158:
4148:
4147:
4146:
4141:
4136:
4126:
4121:
4120:
4119:
4114:
4104:
4103:
4102:
4097:
4092:
4087:
4077:
4076:
4075:
4070:
4060:
4059:
4058:
4053:
4048:
4033:
4031:
4020:
4019:
4017:
4016:
4015:
4014:
4009:
4000:
3996:
3995:
3994:
3989:
3980:
3976:
3975:
3974:
3973:
3972:
3962:
3961:
3960:
3955:
3945:
3940:
3935:
3926:
3922:
3921:
3920:
3916:
3908:
3903:
3901:
3891:
3881:
3880:
3877:
3876:
3874:
3873:
3868:
3863:
3858:
3852:
3850:
3846:
3845:
3842:
3841:
3839:
3838:
3833:
3828:
3823:
3818:
3813:
3807:
3805:
3798:
3797:
3795:
3794:
3788:
3786:
3779:
3778:
3776:
3775:
3770:
3765:
3760:
3755:
3750:
3745:
3740:
3734:
3732:
3725:
3724:
3722:
3721:
3720:
3719:
3714:
3704:
3703:
3702:
3697:
3692:
3687:
3677:
3676:
3675:
3670:
3665:
3654:
3652:
3645:
3644:
3642:
3641:
3636:
3630:
3628:
3627:Cu++ (3.6.3.4)
3621:
3614:
3600:
3599:
3597:
3596:
3591:
3585:
3583:
3577:
3576:
3574:
3573:
3568:
3563:
3562:
3561:
3556:
3545:
3543:
3537:
3536:
3522:
3520:
3519:
3512:
3505:
3497:
3488:
3487:
3479:
3476:
3475:
3473:
3472:
3467:
3462:
3457:
3452:
3447:
3442:
3437:
3431:
3429:
3425:
3424:
3422:
3421:
3412:
3410:
3404:
3403:
3401:
3400:
3391:
3389:
3383:
3382:
3379:
3378:
3376:
3375:
3369:
3367:
3363:
3362:
3360:
3359:
3354:
3344:
3342:
3335:
3334:
3332:
3331:
3325:
3323:
3313:
3306:
3305:
3302:
3301:
3299:
3298:
3293:
3287:
3285:
3281:
3280:
3278:
3277:
3276:
3275:
3270:
3265:
3260:
3255:
3244:
3242:
3238:
3237:
3235:
3234:
3229:
3228:
3227:
3222:
3212:
3206:
3204:
3197:
3196:
3194:
3193:
3192:
3191:
3181:
3180:
3179:
3174:
3164:
3163:
3162:
3157:
3152:
3147:
3137:
3136:
3135:
3130:
3120:
3119:
3118:
3113:
3108:
3103:
3093:
3092:
3091:
3086:
3081:
3071:
3070:
3069:
3064:
3059:
3054:
3049:
3039:
3038:
3037:
3027:
3026:
3025:
3020:
3009:
3007:
2997:
2995:protein kinase
2990:
2989:
2987:
2986:
2981:
2975:
2973:
2969:
2968:
2966:
2965:
2960:
2955:
2949:
2947:
2943:
2942:
2939:
2938:
2936:
2935:
2930:
2925:
2920:
2915:
2910:
2905:
2904:
2903:
2898:
2893:
2883:
2878:
2872:
2870:
2864:
2863:
2860:
2859:
2857:
2856:
2851:
2845:
2842:
2841:
2839:
2838:
2837:
2836:
2831:
2826:
2821:
2816:
2811:
2806:
2801:
2796:
2791:
2786:
2781:
2776:
2768:
2765:
2764:
2763:
2758:
2753:
2748:
2743:
2735:
2728:
2725:
2724:
2722:
2721:
2720:
2719:
2714:
2709:
2704:
2699:
2694:
2689:
2684:
2679:
2674:
2669:
2664:
2659:
2654:
2649:
2644:
2636:
2629:
2626:
2625:
2623:
2622:
2617:
2612:
2607:
2602:
2597:
2591:
2589:
2582:
2581:
2579:
2578:
2573:
2568:
2563:
2558:
2557:
2556:
2541:
2539:
2529:
2527:Heterotrimeric
2520:
2514:
2513:
2511:
2510:
2505:
2500:
2494:
2492:
2488:
2487:
2485:
2484:
2475:
2473:
2469:
2468:
2463:
2461:
2460:
2453:
2446:
2438:
2432:
2431:
2410:
2400:
2388:
2387:External links
2385:
2382:
2381:
2374:
2356:
2319:(3): 117–133.
2290:
2238:
2195:
2177:
2159:
2138:
2116:
2115:
2113:
2110:
2109:
2108:
2103:
2098:
2093:
2088:
2083:
2078:
2073:
2066:
2063:
2062:
2061:
2056:
2051:
2046:
2041:
2037:
2030:
2022:
2010:
2003:
1997:
1976:
1971:
1966:
1962:
1957:
1952:
1947:
1942:
1937:
1930:
1923:
1918:
1913:
1908:
1904:
1897:
1890:
1882:
1877:
1867:
1863:
1856:
1848:
1841:
1834:
1827:
1818:
1814:
1811:
1806:
1798:
1794:
1783:
1764:
1736:
1720:
1713:Main article:
1710:
1707:
1698:
1690:
1686:
1680:
1676:
1668:
1660:
1656:
1650:
1647:alpha subunits
1642:
1634:
1629:by activating
1621:
1610:
1603:
1595:
1588:
1587:
1584:
1583:
1578:
1568:
1567:
1561:
1560:
1557:
1556:
1554:
1552:
1545:
1544:
1537:
1530:
1526:
1525:
1522:
1521:
1509:NP_001297014.1
1505:NP_001070975.1
1485:NP_001297014.1
1481:NP_001070975.1
1451:
1450:
1424:
1421:
1420:
1412:NP_001296812.1
1408:NP_001296812.1
1404:NP_001070958.1
1392:NP_001296769.1
1388:NP_001070958.1
1384:NP_001070957.1
1380:NP_001070956.1
1346:
1345:
1319:
1315:
1314:
1311:
1310:
1276:
1275:
1249:
1246:
1245:
1215:
1214:
1188:
1184:
1183:
1180:
1179:
1159:
1158:
1152:
1149:
1148:
1128:
1127:
1121:
1115:
1114:
1111:
1110:
1102:
1101:
1095:
1092:
1091:
1083:
1082:
1076:
1070:
1069:
1066:
1065:
1057:
1056:
1050:
1047:
1046:
1038:
1037:
1031:
1025:
1024:
1019:
1014:
1010:
1009:
999:
998:
995:
994:
983:
982:
980:
979:
974:
969:
964:
959:
954:
949:
944:
939:
934:
929:
924:
919:
914:
909:
904:
899:
894:
889:
884:
879:
874:
869:
864:
859:
854:
849:
844:
839:
834:
829:
824:
819:
814:
809:
804:
799:
794:
789:
784:
779:
774:
769:
764:
759:
753:
751:
747:
746:
744:
743:
738:
733:
728:
723:
718:
713:
708:
703:
698:
693:
688:
683:
678:
673:
668:
663:
657:
655:
651:
650:
648:
647:
642:
637:
632:
627:
622:
617:
612:
607:
602:
597:
592:
587:
582:
577:
572:
567:
561:
559:
555:
554:
544:
543:
540:
539:
536:
535:
527:
526:
501:
495:
494:
491:
490:
482:
481:
478:
477:
475:
474:
470:
466:
462:
458:
454:
450:
446:
442:
438:
434:
431:
430:
419:
416:
415:
413:
412:
408:
404:
400:
396:
392:
388:
384:
380:
376:
372:
369:
368:
356:
355:
347:
336:
330:
329:
326:RNA expression
318:
317:
314:
313:
305:
301:
300:
292:
289:
284:
278:
277:
268:
261:
255:
251:
250:
245:
239:
238:
230:
229:
217:
216:
213:
212:
204:
200:
199:
191:
188:
183:
177:
176:
167:
160:
154:
150:
149:
142:
136:
135:
127:
126:
114:
113:
70:
66:
65:
57:
49:
48:
44:
43:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
4735:
4724:
4721:
4719:
4716:
4714:
4711:
4709:
4706:
4705:
4703:
4693:
4688:
4683:
4679:
4665:
4661:
4660:
4655:
4652:
4648:
4647:
4642:
4639:
4635:
4634:
4629:
4626:
4622:
4621:
4616:
4613:
4609:
4608:
4603:
4600:
4596:
4595:
4590:
4587:
4583:
4582:
4577:
4576:
4574:
4570:
4564:
4561:
4559:
4556:
4554:
4551:
4549:
4546:
4544:
4541:
4540:
4538:
4534:
4528:
4525:
4523:
4522:Enzyme family
4520:
4518:
4515:
4513:
4510:
4509:
4507:
4503:
4497:
4494:
4492:
4489:
4487:
4486:Cooperativity
4484:
4482:
4479:
4478:
4476:
4472:
4466:
4463:
4461:
4458:
4456:
4453:
4451:
4448:
4446:
4445:Oxyanion hole
4443:
4441:
4438:
4436:
4433:
4431:
4428:
4427:
4425:
4421:
4417:
4410:
4405:
4403:
4398:
4396:
4391:
4390:
4387:
4371:
4368:
4364:
4361:
4359:
4355:
4352:
4350:
4347:
4345:
4342:
4340:
4337:
4336:
4335:
4332:
4331:
4329:
4327:
4322:
4316:
4313:
4309:
4306:
4304:
4301:
4299:
4296:
4295:
4294:
4291:
4290:
4288:
4286:
4281:
4275:
4272:
4270:
4267:
4265:
4262:
4260:
4257:
4253:
4250:
4248:
4245:
4243:
4240:
4238:
4235:
4234:
4233:
4230:
4226:
4223:
4221:
4218:
4217:
4216:
4213:
4209:
4206:
4204:
4201:
4199:
4196:
4195:
4194:
4190:
4189:
4184:
4181:
4179:
4176:
4175:
4174:
4171:
4167:
4164:
4162:
4159:
4157:
4154:
4153:
4152:
4149:
4145:
4142:
4140:
4137:
4135:
4132:
4131:
4130:
4127:
4125:
4122:
4118:
4115:
4113:
4110:
4109:
4108:
4105:
4101:
4098:
4096:
4093:
4091:
4088:
4086:
4083:
4082:
4081:
4078:
4074:
4071:
4069:
4066:
4065:
4064:
4061:
4057:
4054:
4052:
4049:
4047:
4044:
4043:
4042:
4038:
4035:
4034:
4032:
4030:
4026:
4021:
4013:
4010:
4008:
4005:
4004:
4003:
3997:
3993:
3990:
3988:
3985:
3984:
3983:
3977:
3971:
3968:
3967:
3966:
3963:
3959:
3956:
3954:
3951:
3950:
3949:
3946:
3944:
3941:
3939:
3936:
3934:
3931:
3930:
3929:
3923:
3919:
3913:
3912:
3911:
3905:
3904:
3902:
3900:
3895:
3892:
3890:
3886:
3882:
3872:
3869:
3867:
3864:
3862:
3859:
3857:
3854:
3853:
3851:
3847:
3837:
3834:
3832:
3829:
3827:
3824:
3822:
3819:
3817:
3814:
3812:
3809:
3808:
3806:
3804:
3803:P-type ATPase
3799:
3793:
3790:
3789:
3787:
3784:
3780:
3774:
3771:
3769:
3766:
3764:
3761:
3759:
3756:
3754:
3751:
3749:
3746:
3744:
3741:
3739:
3736:
3735:
3733:
3730:
3726:
3718:
3715:
3713:
3710:
3709:
3708:
3705:
3701:
3698:
3696:
3693:
3691:
3688:
3686:
3683:
3682:
3681:
3678:
3674:
3671:
3669:
3666:
3664:
3661:
3660:
3659:
3656:
3655:
3653:
3650:
3646:
3640:
3637:
3635:
3632:
3631:
3629:
3625:
3622:
3618:
3615:
3613:
3609:
3605:
3601:
3595:
3592:
3590:
3587:
3586:
3584:
3582:
3578:
3572:
3569:
3567:
3564:
3560:
3557:
3555:
3552:
3551:
3550:
3547:
3546:
3544:
3542:
3538:
3533:
3529:
3525:
3518:
3513:
3511:
3506:
3504:
3499:
3498:
3495:
3485:
3484:
3477:
3471:
3468:
3466:
3463:
3461:
3458:
3456:
3453:
3451:
3448:
3446:
3443:
3441:
3438:
3436:
3433:
3432:
3430:
3426:
3420:
3419:
3414:
3413:
3411:
3409:
3405:
3399:
3398:
3393:
3392:
3390:
3388:
3384:
3374:
3371:
3370:
3368:
3364:
3358:
3355:
3353:
3349:
3346:
3345:
3343:
3340:
3336:
3330:
3327:
3326:
3324:
3321:
3317:
3314:
3312:
3307:
3297:
3294:
3292:
3289:
3288:
3286:
3282:
3274:
3271:
3269:
3266:
3264:
3261:
3259:
3256:
3254:
3251:
3250:
3249:
3246:
3245:
3243:
3239:
3233:
3230:
3226:
3223:
3221:
3218:
3217:
3216:
3213:
3211:
3208:
3207:
3205:
3202:
3198:
3190:
3187:
3186:
3185:
3182:
3178:
3175:
3173:
3170:
3169:
3168:
3165:
3161:
3158:
3156:
3153:
3151:
3148:
3146:
3143:
3142:
3141:
3138:
3134:
3131:
3129:
3126:
3125:
3124:
3121:
3117:
3114:
3112:
3109:
3107:
3104:
3102:
3099:
3098:
3097:
3094:
3090:
3087:
3085:
3082:
3080:
3077:
3076:
3075:
3072:
3068:
3065:
3063:
3060:
3058:
3055:
3053:
3050:
3048:
3045:
3044:
3043:
3040:
3036:
3033:
3032:
3031:
3028:
3024:
3021:
3019:
3016:
3015:
3014:
3013:Casein kinase
3011:
3010:
3008:
3005:
3001:
2998:
2996:
2991:
2985:
2982:
2980:
2977:
2976:
2974:
2970:
2964:
2961:
2959:
2956:
2954:
2951:
2950:
2948:
2944:
2934:
2931:
2929:
2926:
2924:
2921:
2919:
2916:
2914:
2911:
2909:
2906:
2902:
2899:
2897:
2894:
2892:
2889:
2888:
2887:
2884:
2882:
2879:
2877:
2874:
2873:
2871:
2869:
2865:
2855:
2852:
2850:
2847:
2846:
2843:
2835:
2832:
2830:
2827:
2825:
2822:
2820:
2817:
2815:
2812:
2810:
2807:
2805:
2802:
2800:
2797:
2795:
2792:
2790:
2787:
2785:
2782:
2780:
2777:
2775:
2772:
2771:
2766:
2762:
2759:
2757:
2754:
2752:
2749:
2747:
2744:
2742:
2739:
2738:
2733:
2730:
2729:
2726:
2718:
2715:
2713:
2710:
2708:
2705:
2703:
2700:
2698:
2695:
2693:
2690:
2688:
2685:
2683:
2680:
2678:
2675:
2673:
2670:
2668:
2665:
2663:
2660:
2658:
2655:
2653:
2650:
2648:
2645:
2643:
2640:
2639:
2634:
2631:
2630:
2627:
2621:
2618:
2616:
2613:
2611:
2608:
2606:
2603:
2601:
2598:
2596:
2593:
2592:
2590:
2587:
2583:
2577:
2574:
2572:
2569:
2567:
2564:
2562:
2559:
2555:
2551:
2548:
2547:
2546:
2543:
2542:
2540:
2537:
2533:
2530:
2528:
2524:
2521:
2519:
2515:
2509:
2506:
2504:
2501:
2499:
2496:
2495:
2493:
2489:
2483:
2482:
2477:
2476:
2474:
2470:
2466:
2459:
2454:
2452:
2447:
2445:
2440:
2439:
2436:
2429:
2425:
2424:
2419:
2415:
2411:
2408:
2404:
2401:
2398:
2394:
2391:
2390:
2386:
2377:
2371:
2367:
2360:
2357:
2352:
2348:
2344:
2340:
2335:
2330:
2326:
2322:
2318:
2314:
2310:
2303:
2301:
2299:
2297:
2295:
2291:
2286:
2282:
2278:
2274:
2270:
2266:
2262:
2258:
2251:
2249:
2247:
2245:
2243:
2239:
2234:
2230:
2226:
2222:
2218:
2214:
2210:
2206:
2199:
2196:
2191:
2187:
2181:
2178:
2173:
2169:
2163:
2160:
2156:
2152:
2147:
2145:
2143:
2139:
2135:
2131:
2126:
2124:
2122:
2118:
2111:
2107:
2104:
2102:
2099:
2097:
2094:
2092:
2089:
2087:
2084:
2082:
2079:
2077:
2074:
2072:
2069:
2068:
2064:
2060:
2057:
2055:
2052:
2050:
2047:
2045:
2042:
2040:
2033:
2026:
2023:
2021:
2017:
2014:
2011:
2009:
2001:
1998:
1996:
1992:
1988:
1984:
1980:
1977:
1975:
1972:
1970:
1963:
1961:
1958:
1956:
1953:
1951:
1948:
1946:
1943:
1940:
1933:
1927:
1924:
1922:
1919:
1917:
1914:
1912:
1909:
1907:
1900:
1893:
1886:
1883:
1881:
1878:
1875:
1871:
1868:
1866:
1859:
1852:
1849:
1847:
1844:
1837:
1830:
1824:
1823:
1822:
1812:
1810:
1804:
1791:
1789:
1781:
1777:
1774:
1770:
1762:
1758:
1754:
1750:
1746:
1742:
1734:
1730:
1726:
1716:
1708:
1706:
1704:
1696:
1684:
1672:
1664:
1648:
1640:
1632:
1628:
1624:
1618:
1614:
1606:
1599:
1598:alpha subunit
1582:
1577:
1573:
1569:
1566:
1562:
1555:
1553:
1550:
1546:
1542:
1538:
1535:
1531:
1527:
1520:
1518:
1514:
1510:
1506:
1502:
1498:
1494:
1490:
1486:
1482:
1478:
1474:
1470:
1466:
1462:
1458:
1452:
1448:
1444:
1440:
1436:
1432:
1428:
1425:
1419:
1417:
1413:
1409:
1405:
1401:
1397:
1393:
1389:
1385:
1381:
1377:
1373:
1369:
1365:
1361:
1357:
1353:
1347:
1343:
1339:
1335:
1331:
1327:
1323:
1320:
1316:
1309:
1307:
1303:
1299:
1295:
1291:
1287:
1283:
1277:
1273:
1269:
1265:
1261:
1257:
1253:
1250:
1244:
1242:
1238:
1234:
1230:
1226:
1222:
1216:
1212:
1208:
1204:
1200:
1196:
1192:
1189:
1187:RefSeq (mRNA)
1185:
1178:
1177:
1173:
1169:
1165:
1160:
1156:
1153:
1147:
1146:
1142:
1138:
1134:
1129:
1125:
1122:
1120:
1116:
1109:
1108:
1103:
1099:
1096:
1090:
1089:
1084:
1080:
1077:
1075:
1071:
1064:
1063:
1058:
1054:
1051:
1045:
1044:
1039:
1035:
1032:
1030:
1026:
1023:
1020:
1018:
1015:
1011:
1008:
1004:
1000:
993:
989:
984:
978:
975:
973:
970:
968:
965:
963:
960:
958:
955:
953:
950:
948:
945:
943:
940:
938:
935:
933:
930:
928:
925:
923:
920:
918:
915:
913:
910:
908:
905:
903:
900:
898:
895:
893:
890:
888:
885:
883:
880:
878:
875:
873:
870:
868:
865:
863:
860:
858:
855:
853:
850:
848:
845:
843:
840:
838:
835:
833:
830:
828:
825:
823:
820:
818:
815:
813:
810:
808:
805:
803:
800:
798:
795:
793:
790:
788:
785:
783:
780:
778:
775:
773:
770:
768:
765:
763:
760:
758:
755:
754:
752:
749:
748:
742:
739:
737:
734:
732:
729:
727:
724:
722:
719:
717:
714:
712:
709:
707:
704:
702:
699:
697:
694:
692:
689:
687:
684:
682:
679:
677:
674:
672:
669:
667:
664:
662:
659:
658:
656:
653:
652:
646:
643:
641:
638:
636:
633:
631:
628:
626:
623:
621:
618:
616:
613:
611:
608:
606:
603:
601:
598:
596:
593:
591:
588:
586:
583:
581:
578:
576:
573:
571:
568:
566:
563:
562:
560:
557:
556:
553:
552:Gene ontology
549:
545:
533:
528:
524:
517:
510:
505:
502:
500:
496:
488:
483:
472:
468:
464:
460:
456:
452:
448:
444:
440:
436:
435:
432:
428:
423:
420:
410:
406:
402:
398:
394:
390:
386:
382:
378:
374:
373:
370:
366:
361:
358:
357:
354:
352:
348:
346:
345:
341:
340:
337:
335:
331:
327:
323:
319:
311:
306:
302:
298:
293:
283:
279:
272:
265:
259:
252:
244:
240:
236:
231:
227:
222:
218:
210:
205:
201:
197:
192:
182:
178:
171:
164:
158:
151:
147:
141:
137:
133:
128:
124:
119:
115:
111:
107:
103:
99:
95:
91:
87:
83:
79:
75:
67:
62:
55:
50:
45:
41:
36:
31:
19:
4659:Translocases
4656:
4643:
4630:
4617:
4604:
4594:Transferases
4591:
4578:
4435:Binding site
4172:
4106:
4062:
4040:
4025:Small GTPase
3906:
3639:Wilson/ATP7B
3634:Menkes/ATP7A
3480:
3415:
3394:
3030:eIF-2 kinase
2549:
2478:
2421:
2366:Neuroscience
2365:
2359:
2316:
2312:
2260:
2256:
2208:
2204:
2198:
2189:
2180:
2171:
2162:
1816:
1805:, and each G
1792:
1718:
1619:
1608:
1601:
1593:
1591:
1477:NP_001350959
1454:
1443:NP_001297014
1439:NP_001297012
1435:NP_001070978
1431:NP_001070975
1360:NP_001296812
1356:NP_001296790
1352:NP_001296771
1349:
1342:NP_001296769
1338:NP_001070958
1334:NP_001070957
1330:NP_001070956
1306:NM_001364030
1302:NM_001310085
1298:NM_001310083
1279:
1260:NM_001077510
1256:NM_001077507
1229:NM_001309883
1225:NM_001309861
1221:NM_001309842
1218:
1211:NM_001309840
1207:NM_001077490
1203:NM_001077489
1199:NM_001077488
1162:
1131:
1105:
1086:
1060:
1041:
1021:
1016:
411:frontal pole
349:
342:
308:174,188,537
295:174,126,113
69:External IDs
4430:Active site
4349:Mitofusin-1
4324:3.6.5.5-6:
4293:Prokaryotic
2717:GNA15/GNA16
2503:Calcineurin
2263:: 615–649.
2002:, through G
1965:Histamine H
1767:α binds to
1741:Gβγ complex
1517:NP_963912.1
1513:NP_963911.1
1501:NP_068840.2
1497:NP_062664.2
1493:NP_963911.1
1489:NP_034439.2
1416:NP_536350.2
1400:NP_536351.1
1396:NP_536350.2
1376:NP_000507.1
580:GTP binding
461:human fetus
207:58,911,192
194:58,839,718
47:Identifiers
4713:G proteins
4702:Categories
4633:Isomerases
4607:Hydrolases
4474:Regulation
4315:Eukaryotic
3948:Transducin
3785:(3.6.3.10)
3524:Hydrolases
3123:Lim kinase
3074:IκB kinase
2595:Transducin
2157:, May 2017
2136:, May 2017
2112:References
353:(ortholog)
90:HomoloGene
4512:EC number
4283:3.6.5.3:
4023:3.6.5.2:
3965:Gustducin
3897:3.6.5.1:
3731:(3.6.3.9)
3651:(3.6.3.8)
3554:Inorganic
3481:see also
3387:Apoptosis
2868:Monomeric
2600:Gustducin
2518:G protein
2393:G(s)alpha
1941:receptors
1813:Receptors
1697:, while G
1473:NP_963912
1469:NP_963911
1465:NP_963910
1461:NP_068840
1457:NP_062664
1447:NP_034439
1372:NP_536351
1368:NP_536350
1364:NP_057676
1326:NP_000507
1294:NM_201618
1290:NM_201617
1286:NM_201616
1282:NM_022000
1272:NM_019690
1268:NM_010310
1264:NM_010309
1241:NM_080426
1237:NM_080425
1233:NM_016592
1195:NM_000516
1007:Orthologs
802:cognition
661:cytoplasm
457:CA3 field
375:beta cell
98:GeneCards
4536:Kinetics
4460:Cofactor
4423:Activity
3559:Thiamine
3339:Tyrosine
3284:Arginine
3201:Tyrosine
2351:11025853
2285:33992382
2233:33620092
2225:15272499
2153:–
2132:–
2065:See also
1969:receptor
1926:Dopamine
1872:(a.k.a.
1709:Function
1653:family,
1565:Wikidata
986:Sources:
736:dendrite
701:membrane
186:20q13.32
4692:Biology
4646:Ligases
4416:Enzymes
4370:Tubulin
4339:Dynamin
4191:other:
3871:Katanin
3861:Kinesin
3836:ATP13A3
3831:ATP13A2
3566:Apyrase
3465:EDARADD
3450:Mucin-4
3189:RPS6KA1
3035:EIF2AK3
2491:Calcium
2428:PDBe-KB
2418:UniProt
2343:7579038
2334:1519115
2277:3113327
2155:Ensembl
2134:Ensembl
2006:in the
1803:agonist
1749:hormone
1637:α is a
1119:UniProt
1074:Ensembl
1013:Species
992:QuickGO
691:cytosol
686:nucleus
328:pattern
54:Aliases
4678:Portal
4620:Lyases
4247:ARL13B
4107:RhoBTB
4001:α12/13
3889:GTPase
3866:Myosin
3856:Dynein
3826:ATP12A
3821:ATP11B
3816:ATP10A
3811:ATP8B1
3801:Other
3773:ATP1B4
3768:ATP1B3
3763:ATP1B2
3758:ATP1B1
3753:ATP1A4
3748:ATP1A3
3743:ATP1A2
3738:ATP1A1
3729:Na+/K+
3717:ATP2C2
3712:ATP2C1
3700:ATP2B4
3695:ATP2B3
3690:ATP2B2
3685:ATP2B1
3673:ATP2A3
3668:ATP2A2
3663:ATP2A1
3612:ATPase
3470:PRKCSH
3309:Other
3258:DYRK1B
3253:DYRK1A
2993:Other
2963:Cyclin
2946:Cyclin
2423:P63092
2409:(MeSH)
2399:(MeSH)
2372:
2349:
2341:
2331:
2283:
2275:
2231:
2223:
2027:types
1887:types
1853:types
1705:gene.
1683:family
1673:, and
1671:family
1663:family
1639:GTPase
1551:search
1549:PubMed
1176:Q6R0H6
1172:Q9Z0F1
1168:Q6R0H7
1164:P63094
1145:Q5JWF2
1141:P84996
1137:P63092
1133:O95467
1029:Entrez
726:ruffle
499:BioGPS
473:dermis
78:139320
4572:Types
4303:EF-Tu
4242:SAR1B
4225:RAB27
4220:RAB23
4173:RhoDF
4063:RhoUV
4046:CDC42
4041:Cdc42
4027:>
4012:GNA13
4007:GNA12
3992:GNA11
3981:αq/11
3970:GNAT3
3958:GNAT2
3953:GNAT1
3943:GNAI3
3938:GNAI2
3933:GNAI1
3885:3.6.5
3849:3.6.4
3792:ATP4A
3783:H+/K+
3658:SERCA
3620:3.6.3
3604:3.6.3
3581:3.6.2
3541:3.6.1
3428:Other
3366:both:
3273:DYRK4
3268:DYRK3
3263:DYRK2
3225:PTK2B
3210:ZAP70
3177:ROCK2
3172:ROCK1
3133:LIMK2
3128:LIMK1
3116:IRAK4
3111:IRAK3
3106:IRAK2
3101:IRAK1
3089:IKBKG
3067:GSK3B
3062:GSK3A
3057:GSK-3
2972:Lipid
2923:Rhebs
2834:BSCL2
2829:GNG13
2824:GNG12
2819:GNG11
2814:GNG10
2779:GNGT2
2774:GNGT1
2712:GNA14
2707:GNA13
2702:GNA12
2697:GNA11
2672:GNAT3
2667:GNAT2
2662:GNAT1
2657:GNAI3
2652:GNAI2
2647:GNAI1
2642:GNAO1
2347:S2CID
2281:S2CID
2229:S2CID
2020:PTH2R
2016:PTH1R
1062:14683
1022:Mouse
1017:Human
988:Amigo
351:Mouse
344:Human
291:Start
226:Mouse
190:Start
123:Human
94:55534
86:95777
4664:list
4657:EC7
4651:list
4644:EC6
4638:list
4631:EC5
4625:list
4618:EC4
4612:list
4605:EC3
4599:list
4592:EC2
4586:list
4579:EC1
4363:OPA1
4356:and
4308:EF-G
4298:IF-2
4264:Rheb
4252:ARL6
4237:ARF6
4208:NRAS
4203:KRAS
4198:HRAS
4183:RhoD
4178:RhoF
4124:RhoH
4100:RhoG
4085:Rac1
4073:RhoV
4068:RhoU
4051:TC10
3987:GNAQ
3707:SPCA
3534:3.6)
3416:see
3395:see
3296:McsB
3220:PTK2
3160:PAK4
3155:PAK3
3150:PAK2
3145:PAK1
3084:IKK2
3079:CHUK
3052:GSK2
3047:GSK1
2933:RGKs
2928:Raps
2913:Arfs
2908:Rhos
2901:NRAS
2896:KRAS
2891:HRAS
2881:Rabs
2876:ARFs
2809:GNG8
2804:GNG7
2799:GNG5
2794:GNG4
2789:GNG3
2784:GNG2
2761:GNB5
2756:GNB4
2751:GNB3
2746:GNB2
2741:GNB1
2692:GNAQ
2687:GNAL
2682:GNAS
2677:GNAZ
2610:cGMP
2586:cGMP
2566:cAMP
2536:cAMP
2479:see
2416:for
2370:ISBN
2339:PMID
2273:PMID
2221:PMID
2034:and
2018:and
1995:MC5R
1991:MC4R
1987:MC3R
1983:MC1R
1934:and
1901:and
1874:MC2R
1860:and
1840:5-HT
1838:and
1833:5-HT
1826:5-HT
1788:here
1776:cAMP
1703:GNAL
1592:The
1043:2778
334:Bgee
282:Band
243:Chr.
181:Band
140:Chr.
102:GNAS
74:OMIM
61:GNAS
33:GNAS
4358:MX2
4354:MX1
4274:RGK
4269:Rap
4259:Ran
4232:Arf
4215:Rab
4193:Ras
4151:Rnd
4129:Rho
4080:Rac
4056:TCL
3917:olf
3649:Ca+
3232:BTK
2918:Ran
2886:Ras
2472:MAP
2414:PDB
2329:PMC
2321:doi
2265:doi
2213:doi
2004:olf
1761:GTP
1751:or
1745:GDP
1699:olf
1687:olf
1681:α13
1677:α12
1633:. G
304:End
203:End
106:OMA
82:MGI
18:Gsα
4704::
4039::
3927:αi
3909:αs
3887::
3610::
3532:EC
3526::
3350::
2554:Gi
2550:Gs
2420::
2345:.
2337:.
2327:.
2317:15
2315:.
2311:.
2293:^
2279:.
2271:.
2261:56
2259:.
2241:^
2227:.
2219:.
2207:.
2188:.
2170:.
2141:^
2120:^
1993:,
1989:,
1981::
1894:,
1864:2b
1857:2a
1831:,
1790:.
1679:/G
1669:αq
1665:,
1661:αo
1659:/G
1657:αi
1651:αs
1607:,
1604:αs
990:/
310:bp
297:bp
209:bp
196:bp
104:;
100::
96:;
92::
88:;
84::
80:;
76::
4680::
4666:)
4662:(
4653:)
4649:(
4640:)
4636:(
4627:)
4623:(
4614:)
4610:(
4601:)
4597:(
4588:)
4584:(
4408:e
4401:t
4394:v
4166:3
4161:2
4156:1
4144:C
4139:B
4134:A
4117:2
4112:1
4095:3
4090:2
3999:G
3979:G
3925:G
3915:G
3907:G
3608:4
3606:-
3530:(
3516:e
3509:t
3502:v
3341::
3322::
3203::
3023:2
3018:1
3006::
2769:γ
2767:G
2736:β
2734:G
2637:α
2635:G
2588::
2552:/
2538::
2457:e
2450:t
2443:v
2430:.
2378:.
2353:.
2323::
2287:.
2267::
2235:.
2215::
2209:3
2192:.
2174:.
2038:2
2036:I
2031:2
2029:D
1967:2
1938:5
1936:D
1931:1
1929:D
1905:3
1903:β
1898:2
1896:β
1891:1
1889:β
1876:)
1862:A
1855:A
1842:7
1835:6
1828:4
1819:s
1807:s
1799:s
1795:s
1784:s
1765:s
1737:s
1721:s
1691:s
1675:G
1667:G
1655:G
1643:s
1635:s
1622:s
1620:G
1613:α
1611:s
1609:G
1602:G
1600:(
1596:s
1594:G
228:)
125:)
108::
20:)
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