740:, the United States, and many other countries. Varicella vaccination has raised concerns in some that the immunity induced by the vaccine may not be lifelong, possibly leaving adults vulnerable to more severe disease as the immunity from their childhood immunization wanes. Vaccine coverage in the United States in the population recommended for vaccination is approaching 90%, with concomitant reductions in the incidence of varicella cases and hospitalizations and deaths due to VZV. So far, clinical data has proved that the vaccine is effective for over ten years in preventing varicella infection in healthy individuals, and when
651:(SNP) present in ORF22, and the E1 and E2 genotypes were resolved using SNP located in ORF21, ORF22 or ORF50. Sequence analysis of 342 clinical varicella and zoster specimens from 18 European countries identified the following distribution of VZV genotypes: E1, 221 (65%); E2, 87 (25%); M1, 20 (6%); M2, 3 (1%); M4, 11 (3%). No M3 or J strains were observed. Of 165 clinical varicella and zoster isolates from Australia and New Zealand typed using this approach, 67 of 127 eastern Australian isolates were E1, 30 were E2, 16 were J, 10 were M1, and 4 were M2; 25 of 38 New Zealand isolates were E1, 8 were E2, and 5 were M1.
42:
647:(E1, E2, J, M1, M2, M3, M4, VIII and IX). Complete sequences for M3 and M4 strains are unavailable, but targeted analyses of representative strains suggest they are stable, circulating VZV genotypes. Sequence analysis of VZV isolates identified both shared and specific markers for every genotype and validated a unified VZV genotyping strategy. Despite high genotype diversity no evidence for intra-genotypic recombination was observed. Five of seven VZV genotypes were reliably discriminated using only four
67:
3325:
575:
476:
636:. Clade 4 includes some strains from Europe but its geographic origins need further clarification. There are also four genotypes that do not fit into these clades. Allocation of VZV strains to clades required the sequence of whole virus genome. Practically all molecular epidemiological data on global VZV strains distribution are obtained with targeted
360:, the period of illness lasts about 3 to 4 days. Infected individuals are most contagious 1–2 days before the lesions appear. Signs and symptoms include vesicles that fill with pus, rupture, and scab before healing. Lesions most commonly occur on the face, throat, the lower back, the chest and shoulders.
461:
long. The capsid is surrounded by loosely associated proteins known collectively as the tegument; many of these proteins play critical roles in initiating the process of virus reproduction in the infected cell. The tegument is in turn covered by a lipid envelope studded with glycoproteins that are
372:
or herpes zoster. The individual lifetime risk of developing herpes zoster is thought to be between 20% and 30%, or approximately 1 in 4 people. However, for people aged 85 and over, this risk increases to 1 in 2. In a study in Sweden by
Nilsson et al. (2015) the annual incidence of herpes zoster
774:
which was approved in the United States by the FDA in
October 2017. The ACIP recommended Shingrix for adults over the age of 50, including those who have already received Zostavax. The committee voted that Shingrix is preferred over Zostavax for the prevention of zoster and related complications
795:
Chickenpox-like rashes were recognized and described by ancient civilizations; the relationship between zoster and chickenpox was not realized until 1888. In 1943, the similarity between virus particles isolated from the lesions of zoster and those from chickenpox was noted. In 1974 the first
407:
giving lesions that follow specific branches of the facial nerve. Symptoms may include painful blisters on the tongue and ear along with one-sided facial weakness and hearing loss. After infection during initial stages of pregnancy, the fetus can be severely damaged.
387:, almost always on one side of the body only. The skin lesions usually subside over the course of several weeks, while the pain often persists longer. In 10–15% of cases the pain persists more than three months, a chronic and often disabling condition known as
694:. Acyclovir is frequently used as the drug of choice in primary VZV infections, and beginning its administration early can significantly shorten the duration of any symptoms. However, reaching an effective serum concentration of acyclovir typically requires
412:
can happen after initial infection, causing continuous vomiting and signs of brain dysfunction such as extreme drowsiness or combative behavior. In some cases, death or coma can follow. Reye's syndrome mostly affects children and teenagers; using
775:
because phase 3 clinical data showed vaccine efficacy of >90% against shingles across all age groups, as well as sustained efficacy over a four-year follow-up. Unlike
Zostavax, which is given as a single shot, Shingrix is given as two
433:(gB, gC, gE, gH, gI, gK, gL) correspond with those in HSV; however, there is no equivalent of the HSV gD protein. VZV also fails to produce the LAT (latency-associated transcripts) that play an important role in establishing HSV
755:
for the prevention of shingles. Zostavax is a more concentrated formulation of the
Varivax vaccine, designed to elicit an immune response in older adults whose immunity to VZV wanes with advancing age. A systematic review by
2040:
Ligon BL (January 2002). "Thomas Huckle Weller MD: Nobel
Laureate and research pioneer in poliomyelitis, varicella-zoster virus, cytomegalovirus, rubella, and other infectious diseases".
1588:"Identification of five major and two minor genotypes of varicella-zoster virus strains: a practical two-amplicon approach used to genotype clinical isolates in Australia and New Zealand"
929:
860:
380:, with a 2013 article reporting an incidence rate of 1.02 cases per 100,000 inhabitants in Switzerland, and an annual incidence rate of 1.8 cases per 100,000 inhabitants in Sweden.
3529:
1780:
de
Oliveira Gomes J, Gagliardi AM, Andriolo BN, Torloni MR, Andriolo RB, Puga ME, Canteiro Cruz E (October 2023). "Vaccines for preventing herpes zoster in older adults".
545:(inverted S) which are present with equal frequency for a total frequency of 90–95%. The L segment can also be inverted resulting in a total of four linear isomers (I
4414:
3319:
4468:
4312:
1050:
Harpaz R, Ortega-Sanchez IR, Seward JF (June 2008). "Prevention of herpes zoster: recommendations of the
Advisory Committee on Immunization Practices (ACIP)".
1870:"Safety and immunogenicity of an adjuvanted herpes zoster subunit candidate vaccine in HIV-infected adults: a phase 1/2a randomized, placebo-controlled study"
745:
666:
mutation rates among the herpesviruses have been estimated at 1 × 10 and 2.7 × 10 mutations/site/year, respectively, based on the highly conserved gB gene.
632:
of this virus. Clades 1 and 3 include
European/North American strains; clade 2 are Asian strains, especially from Japan; and clade 5 appears to be based in
1498:"Distribution of varicella-zoster virus (VZV) wild-type genotypes in northern and southern Europe: evidence for high conservation of circulating genotypes"
4115:
3359:
3786:
553:). This is distinct from HSV's equiprobable distribution, and the discriminatory mechanism is not known. A small percentage of isolated molecules are
621:; five genes (out of about 70) do not have corresponding HSV genes. Relation with other human herpes viruses is less strong, but many homologues and
3522:
1979:
Takahashi M, Otsuka T, Okuno Y, Asano Y, Yazaki T (November 1974). "Live vaccine used to prevent the spread of varicella in children in hospital".
373:
infection is estimated at a total of 315 cases per 100,000 inhabitants for all ages and 577 cases per 100,000 for people 50 years of age or older.
2147:
1720:"Prevention of varicella: Recommendations of the Advisory Committee on Immunization Practices (ACIP). Centers for Disease Control and Prevention"
336:(either viral bronchitis or secondary bacterial bronchitis). Even when clinical symptoms of chickenpox have resolved, VZV remains dormant in the
872:
586:
about genotype-clade mapping (use existing sources); widespread recombination and clade produced by recombination (use "9geno"); clade 6 (use
736:(FDA) for approval in 1990 and was approved in 1995. Since then, it has been added to the recommended vaccination schedules for children in
4317:
1846:
383:
Shingles lesions and the associated pain, often described as burning, tend to occur on the skin that is innervated by one or two adjacent
3515:
3423:
3038:
836:
3203:
2672:
2567:
1635:
McGeoch DJ, Cook S (April 1994). "Molecular phylogeny of the alphaherpesvirinae subfamily and a proposed evolutionary timescale".
3717:
3153:
3033:
2782:
748:(ACIP) recommended a second dose of vaccine before school entry to ensure the maintenance of high levels of varicella immunity.
4039:
3328:
3113:
1820:
4506:
4054:
3352:
3098:
3093:
648:
4271:
3296:
2907:
2802:
2727:
2627:
2622:
2607:
2602:
2537:
2512:
1749:
Marin M, Güris D, Chaves SS, Schmid S, Seward JF, et al. (Advisory
Committee On Immunization Practices) (June 2007).
1389:"Bioinformatics of varicella-zoster virus: single nucleotide polymorphisms define clades and attenuated vaccine genotypes"
1181:"Infection of the central nervous system caused by varicella zoster virus reactivation: a retrospective case series study"
989:
Steiner I, Kennedy PG, Pachner AR (November 2007). "The neurotropic herpes viruses: herpes simplex and varicella-zoster".
4337:
66:
4283:
3281:
3276:
3058:
3043:
2993:
2882:
2877:
2872:
2822:
2507:
2467:
733:
400:
4392:
1826:. Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, US Food and Drug Administration
4327:
4218:
3963:
3697:
3413:
3271:
3266:
3256:
3193:
3158:
3053:
2657:
2597:
2592:
2532:
2492:
2440:
2140:
807:
also isolated the virus and found evidence that the same virus was responsible for both chickenpox and herpes zoster.
597:
498:
255:
810:
The etymology of the name of the virus comes from the two diseases it causes, varicella and herpes zoster. The word
41:
4017:
3707:
3702:
3645:
3428:
3418:
3246:
3241:
3108:
3073:
3068:
2947:
2912:
2797:
2792:
2667:
2617:
2582:
2557:
663:
4473:
4501:
4332:
3918:
3345:
3251:
3198:
3103:
3063:
2987:
2817:
2812:
2732:
2687:
2682:
2677:
2652:
2647:
2612:
2562:
2502:
2497:
2487:
2462:
2350:
527:
4138:
4024:
3610:
3291:
3286:
3261:
3188:
3183:
3178:
3118:
3048:
2981:
2937:
2932:
2902:
2807:
2777:
2772:
2722:
2717:
2712:
2707:
2702:
2697:
2692:
2662:
2577:
2572:
954:
Nagel MA, Gilden DH (July 2007). "The protean neurologic manifestations of varicella-zoster virus infection".
487:
about
Annotated ORFs, like we did for HSV. (Or at least the interesting parts -- maybe differences from HSV?)
392:
4288:
3958:
3620:
3133:
3128:
3123:
2952:
2942:
2852:
2847:
2842:
2787:
2737:
2360:
2355:
2315:
776:
757:
659:
1539:"Sequencing of 21 varicella-zoster virus genomes reveals two novel genotypes and evidence of recombination"
4354:
3712:
3408:
2957:
2390:
2385:
2380:
2330:
2325:
2320:
2133:
841:
741:
687:
388:
377:
3507:
4179:
4144:
4067:
3324:
2418:
1672:"FDA approval of an extended period for administering VariZIG for postexposure prophylaxis of varicella"
278:
1321:
557:, about which little is known. (It is known that HSV circularizes on infection.) There are at least 70
4401:
4241:
3882:
3872:
3586:
1751:"Prevention of varicella: recommendations of the Advisory Committee on Immunization Practices (ACIP)"
1400:
831:
804:
426:
349:
270:
235:
61:
4496:
3791:
3742:
3454:
2295:
2290:
2285:
2202:
695:
554:
404:
329:
49:
4034:
3923:
3777:
3640:
3605:
3575:
3496:
2972:
2431:
1961:
1014:
729:
622:
558:
353:
282:
186:
151:
4322:
3913:
1220:
Nagel MA, Cohrs RJ, Mahalingam R, Wellish MC, Forghani B, Schiller A, et al. (March 2008).
900:
409:
4419:
1496:
Loparev VN, Rubtcova EN, Bostik V, Tzaneva V, Sauerbrei A, Robo A, et al. (January 2009).
437:(herpes simplex virus). VZV virions are spherical and 180–200 nm in diameter. Their lipid
356:
and has an incubation period of 10–21 days, with an average of 14 days. Targeting the skin and
4455:
4266:
4110:
4029:
4007:
3877:
3732:
3635:
3470:
3024:
2752:
2261:
2057:
1996:
1926:
1899:
1868:
Berkowitz EM, Moyle G, Stellbrink HJ, Schürmann D, Kegg S, Stoll M, et al. (April 2015).
1801:
1762:
1731:
1686:
1652:
1617:
1568:
1519:
1475:
1426:
1369:
1302:
1251:
1202:
1161:
1110:
1059:
1006:
971:
707:
674:
Within the human body it can be treated by a number of drugs and therapeutic agents including
587:
523:
488:
1586:
Loparev VN, Rubtcova EN, Bostik V, Govil D, Birch CJ, Druce JD, et al. (December 2007).
3989:
3978:
3759:
3600:
2095:
2087:
2049:
1988:
1953:
1889:
1881:
1797:
1789:
1644:
1607:
1599:
1558:
1550:
1509:
1465:
1457:
1446:"Pangaea and the Out-of-Africa Model of Varicella-Zoster Virus Evolution and Phylogeography"
1416:
1408:
1359:
1292:
1282:
1241:
1233:
1192:
1151:
1141:
1100:
1090:
1079:"Similar herpes zoster incidence across Europe: results from a systematic literature review"
998:
963:
357:
345:
1222:"The varicella zoster virus vasculopathies: clinical, CSF, imaging, and virologic features"
4170:
3845:
3766:
2833:
2763:
771:
767:
325:
1750:
1719:
1708:(3rd ed.). Philadelphia: Lippincott Williams & Wilkins Health. pp. 255–272.
1404:
596:
Please expand the section to include this information. Further details may exist on the
497:
Please expand the section to include this information. Further details may exist on the
285:. Many years after the person has recovered from initial chickenpox infection, VZV can
17:
4128:
4099:
4072:
4049:
3862:
3625:
3538:
3475:
3382:
3315:
2638:
2188:
2176:
2100:
2075:
1894:
1869:
1612:
1587:
1563:
1538:
1470:
1445:
1421:
1388:
1246:
1237:
1221:
1156:
1129:
1105:
1078:
780:
760:(updated in 2023) shows that Zostavax reduces the incidence of shingles by almost 50%.
725:
711:
637:
618:
438:
368:
In about a third of cases, VZV reactivates in later life, producing a disease known as
337:
163:
103:
1992:
1297:
1270:
1002:
4490:
4207:
4105:
3928:
3819:
3564:
3403:
2863:
2409:
2341:
2276:
2182:
2170:
2158:
655:
384:
341:
262:-specific to humans. The virus can survive in external environments for a few hours.
243:
239:
139:
127:
115:
91:
1965:
643:
Phylogenetic analysis of VZV genomic sequences resolves wild-type strains into nine
4460:
4257:
4089:
4012:
4002:
3949:
3909:
3900:
3748:
3232:
3144:
2923:
2548:
2371:
2306:
1793:
1018:
800:
683:
430:
317:
2118:
1179:
Becerra JC, Sieber R, Martinetti G, Costa ST, Meylan P, Bernasconi E (July 2013).
4446:
1412:
4386:
4246:
3214:
2235:
2125:
1514:
1497:
1364:
1347:
679:
1537:
Zell R, Taudien S, Pfaff F, Wutzler P, Platzer M, Sauerbrei A (February 2012).
1197:
1180:
4276:
4232:
3889:
3808:
3687:
3449:
3398:
3169:
3006:
2523:
2478:
2015:
1821:"Biologics License Application (BLA) for Zoster Vaccine Recombinant, Adjuvant"
1146:
691:
458:
333:
313:
307:
247:
1671:
1095:
936:. Pathogen Regulation Directorate, Public Health Agency of Canada. 2012-04-30
930:"Pathogen Safety Data Sheets: Infectious Substances – Varicella-zoster virus"
4197:
4160:
4044:
3630:
3554:
3480:
3444:
3084:
2893:
2453:
2217:
2053:
1885:
737:
675:
534:
462:
displayed on the exterior of the virion, each approximately 8 nm long.
450:
446:
321:
2091:
2061:
1930:
1903:
1805:
1766:
1690:
1648:
1621:
1572:
1523:
1479:
1430:
1255:
1206:
1165:
1114:
1063:
1010:
975:
591:
574:
492:
475:
273:, after primary infection with VZV (chickenpox), the virus lies dormant in
254:
in adults but rarely in children. As a late complication of VZV infection,
2000:
1735:
1656:
1373:
1322:"General Characteristics and Epidemiology of varicella-zoster virus (VZV)"
1306:
967:
4440:
4377:
4371:
3867:
3838:
3833:
3828:
3692:
1603:
1554:
1461:
819:
763:
752:
644:
395:, zoster multiplex, and inflammation of arteries in the brain leading to
369:
290:
251:
1287:
4213:
4184:
3953:
3933:
3754:
3667:
3657:
2587:
1957:
721:
720:
is available and is marketed in the United States under the trade name
717:
414:
259:
3857:
3615:
3595:
698:
administration, making its use more difficult outside of a hospital.
538:
519:
442:
396:
274:
266:
4348:
1077:
Pinchinat S, Cebrián-Cuenca AM, Bricout H, Johnson RW (April 2013).
541:, depending on the orientation of the S segment, P (prototype) and I
391:. Other serious complications of varicella zoster infection include
3337:
3542:
728:
in the 1980s from the Oka strain virus isolated and attenuated by
633:
629:
78:
4406:
3998:
3850:
1944:
Ruska H (1943). "Über das Virus der Varicellen und des Zoster".
4352:
3511:
3341:
2129:
2121:. Centers for Disease Control and Prevention (CDC). 2017-07-07.
1130:"Burden of herpes zoster and post-herpetic neuralgia in Sweden"
1030:
1028:
784:
568:
530:
469:
454:
1917:
Wood MJ (October 2000). "History of Varicella Zoster Virus".
779:
doses, two to six months apart. This vaccine has shown to be
457:
is a single, linear, double-stranded molecule, 125,000
399:, myelitis, herpes ophthalmicus, or zoster sine herpete. In
1847:"ACIP: New Vaccine Recommendations for Shingles Prevention"
1670:
Centers for Disease Control Prevention (CDC) (March 2012).
316:(varicella), which may result in complications including
744:
do occur, illness is typically mild. In 2006, the CDC's
732:
and colleagues in the 1970s. It was submitted to the US
429:(HSV), sharing much genome homology. The known envelope
269:, and causes a wide variety of symptoms. Similar to the
2016:"Pioneering Molecular Biologist Dies of COVID-19 at 89"
1348:"The complete DNA sequence of varicella-zoster virus"
909:
International Committee on Taxonomy of Viruses (ICTV)
888:
Human herpesvirus 3 (HHV-3) (Varicella-zoster virus)
869:
International Committee on Taxonomy of Viruses (ICTV)
312:
Primary varicella zoster virus infection results in
4430:
4361:
4305:
4255:
4230:
4195:
4168:
4159:
4126:
4087:
3987:
3976:
3942:
3898:
3817:
3806:
3775:
3730:
3676:
3654:
3584:
3573:
3562:
3553:
3489:
3463:
3437:
3391:
3373:
3230:
3212:
3167:
3142:
3082:
3022:
3004:
2970:
2921:
2891:
2861:
2831:
2761:
2750:
2636:
2546:
2521:
2476:
2451:
2429:
2407:
2369:
2339:
2304:
2274:
2259:
2233:
2215:
2200:
803:while she was working at Cleveland City Hospital.
250:commonly affecting children and young adults, and
799:The varicella zoster virus was first isolated by
27:Herpes virus that causes chickenpox and shingles
1706:Lippincott's illustrated reviews: Microbiology
258:may develop in rare cases. VZV infections are
4313:Asymmetric periflexural exanthem of childhood
3523:
3353:
3318:species listed below parent taxon –– Source:
2141:
1128:Nilsson J, Cassel T, Lindquist L (May 2015).
8:
1387:Chow VT, Tipples GA, Grose C (August 2013).
1185:International Journal of Infectious Diseases
746:Advisory Committee on Immunization Practices
1782:The Cochrane Database of Systematic Reviews
1679:MMWR. Morbidity and Mortality Weekly Report
617:Commonality with HSV1 and HSV2 indicates a
4349:
4165:
4116:Papular purpuric gloves and socks syndrome
3984:
3814:
3581:
3570:
3559:
3550:
3530:
3516:
3508:
3360:
3346:
3338:
3001:
2758:
2448:
2426:
2271:
2267:
2212:
2208:
2148:
2134:
2126:
822:coined by Rudolph Augustin Vogel in 1764.
533:molecule, a laboratory strain has 124,884
40:
29:
2099:
2042:Seminars in Pediatric Infectious Diseases
1893:
1611:
1562:
1513:
1469:
1420:
1363:
1296:
1286:
1245:
1196:
1155:
1145:
1104:
1094:
417:during infection can increase this risk.
1491:
1489:
3787:Kaposi's sarcoma-associated herpesvirus
1849:. Medical Professionals Reference (MPR)
1346:Davison AJ, Scott JE (September 1986).
1328:. Medical Professionals Reference (MPR)
852:
716:A live attenuated VZV Oka/Merck strain
453:arranged in an icosahedral form. Its
7:
4318:Post-vaccination follicular eruption
2119:"Varicella (Chickenpox) Vaccination"
2076:"Etymologia: Varicella Zoster Virus"
1326:The Lecturio Medical Concept Library
956:Cleveland Clinic Journal of Medicine
796:chickenpox vaccine was introduced.
770:(HHV3 glycoprotein E) developed by
3424:Progressive outer retinal necrosis
1874:The Journal of Infectious Diseases
1238:10.1212/01.wnl.0000304747.38502.e8
837:Progressive outer retinal necrosis
198:Human herpesvirus 3, HHV-3, HHV3,
25:
1755:MMWR. Recommendations and Reports
1724:MMWR. Recommendations and Reports
1393:Infection, Genetics and Evolution
1052:MMWR. Recommendations and Reports
537:. The genome has two predominant
4333:Viral-associated trichodysplasia
3718:Modified varicella-like syndrome
3541:, symptoms and signs related to
3323:
962:(7): 489–94, 496, 498–9 passim.
573:
474:
65:
4040:Epidermodysplasia verruciformis
1919:Herpes: The Journal of the IHMF
1352:The Journal of General Virology
649:single nucleotide polymorphisms
4055:Verrucae palmares et plantares
1794:10.1002/14651858.CD008858.pub5
425:VZV is closely related to the
308:Chickenpox § Epidemiology
1:
4272:Hand, foot, and mouth disease
3767:Cytomegalic inclusion disease
1993:10.1016/s0140-6736(74)90144-5
1819:Gruber MF (20 October 2017).
1275:Clinical Microbiology Reviews
1037:Microbiology: An Introduction
1003:10.1016/S1474-4422(07)70267-3
4284:Foot-and-mouth disease virus
3414:Ramsay Hunt syndrome type II
2080:Emerging Infectious Diseases
1637:Journal of Molecular Biology
1413:10.1016/j.meegid.2012.11.008
1039:. Pearson. pp. 601–602.
785:human immunodeficiency virus
734:Food and Drug Administration
4328:Eruptive pseudoangiomatosis
4219:Congenital rubella syndrome
3964:Molluscum contagiosum virus
2014:Frellick M (July 1, 2020).
1515:10.1016/j.virol.2008.10.026
1365:10.1099/0022-1317-67-9-1759
281:, dorsal root ganglia, and
256:Ramsay Hunt syndrome type 2
195:Varicella-zoster virus, VZV
4523:
3708:Disseminated herpes zoster
3646:Herpetic gingivostomatitis
3419:Disseminated herpes zoster
1845:Han HD (25 October 2017).
1730:(RR-11): 1–36. July 1996.
1444:Grose C (September 2012).
1320:Han DH (25 October 2017).
1198:10.1016/j.ijid.2013.01.031
1058:(RR-5): 1–30, quiz CE2-4.
751:In 2006, the FDA approved
705:
305:
4063:
3919:Bovine papular stomatitis
3549:
3313:
2270:
2211:
2166:
1147:10.1186/s12879-015-0951-7
814:is possibly derived from
441:encloses the 100 nm
352:. VZV enters through the
340:of the infected person (
192:
185:
60:
48:
39:
32:
4432:Human alphaherpesvirus 3
4393:Human alphaherpesvirus 3
4338:Gianotti–Crosti syndrome
4139:Merkel cell polyomavirus
4025:Laryngeal papillomatosis
3611:Herpes simplex keratitis
1271:"Varicella-zoster virus"
1096:10.1186/1471-2334-13-170
903:Human alphaherpesvirus 3
901:"ICTV Taxonomy history:
861:"ICTV 9th Report (2011)
783:and safe in adults with
726:Merck, Sharp & Dohme
628:There are at least five
625:blocks are still found.
526:in 1986. It is a linear
376:VZV can also infect the
252:shingles (herpes zoster)
238:), is one of nine known
231:Human alphaherpesvirus 3
200:Human alphaherpesvirus 3
178:Human alphaherpesvirus 3
54:Human alphaherpesvirus 3
34:Human alphaherpesvirus 3
18:Human alphaherpesvirus 3
4289:Boston exanthem disease
3959:Yaba monkey tumor virus
3641:Herpetiform esophagitis
3621:Neonatal herpes simplex
2054:10.1053/spid.2002.31314
1704:Cornelissen CN (2013).
1134:BMC Infectious Diseases
1083:BMC Infectious Diseases
742:breakthrough infections
3713:Zoster-associated pain
3409:Postherpetic neuralgia
3375:Varicella zoster virus
2092:10.3201/eid2104.ET2104
1649:10.1006/jmbi.1994.1264
1269:Arvin AM (July 1996).
842:Simian varicella virus
724:. It was developed by
688:zoster-immune globulin
584:is missing information
485:is missing information
427:herpes simplex viruses
389:postherpetic neuralgia
378:central nervous system
271:herpes simplex viruses
265:VZV multiplies in the
248:chickenpox (varicella)
210:Varicella zoster virus
4507:Animal viral diseases
4145:Merkel cell carcinoma
4068:Bovine papillomavirus
1886:10.1093/infdis/jiu606
991:The Lancet. Neurology
968:10.3949/ccjm.74.7.489
640:of selected regions.
393:Mollaret's meningitis
279:cranial nerve ganglia
4242:Alphavirus infection
4106:Erythema infectiosum
3883:Progressive vaccinia
3873:Generalized vaccinia
3698:Herpes zoster oticus
1604:10.1128/JVI.01145-07
1555:10.1128/JVI.06233-11
1462:10.1128/JVI.00357-12
875:on December 22, 2018
832:Herpes simplex virus
805:Thomas Huckle Weller
401:Ramsay Hunt syndrome
62:Virus classification
4363:Human herpesvirus 3
3743:Human herpesvirus 6
3455:VZV immune globulin
2203:Malacoherpesviridae
1592:Journal of Virology
1543:Journal of Virology
1450:Journal of Virology
1405:2013InfGE..18..351C
1288:10.1128/CMR.9.3.361
886:Human herpesvirus 3
559:open reading frames
405:geniculate ganglion
350:dorsal root ganglia
330:bacterial pneumonia
218:human herpesvirus 3
50:Electron micrograph
4221:("German measles")
4035:Bowenoid papulosis
3606:Herpes gladiatorum
3497:Michiaki Takahashi
1958:10.1007/bf01768631
1952:(46–47): 703–704.
730:Michiaki Takahashi
686:for the shingles,
403:, VZV affects the
354:respiratory system
153:Orthoherpesviridae
4484:
4483:
4355:Taxon identifiers
4346:
4345:
4301:
4300:
4297:
4296:
4267:Coxsackie A virus
4247:Chikungunya fever
4155:
4154:
4111:Reticulocytopenia
4083:
4082:
3972:
3971:
3878:Eczema vaccinatum
3802:
3801:
3755:Exanthema subitum
3726:
3725:
3703:Ophthalmic zoster
3668:B virus infection
3636:Eczema herpeticum
3505:
3504:
3471:Varicella vaccine
3429:Ophthalmic zoster
3335:
3334:
3309:
3308:
3305:
3304:
3025:Lymphocryptovirus
2998:
2997:
2966:
2965:
2746:
2745:
2445:
2444:
2423:
2422:
2403:
2402:
2399:
2398:
2262:Alloherpesviridae
2255:
2254:
2251:
2250:
2168:Higher taxonomy:
1987:(7892): 1288–90.
708:varicella vaccine
615:
614:
516:
515:
358:peripheral nerves
283:autonomic ganglia
244:can infect humans
216:), also known as
207:
206:
16:(Redirected from
4514:
4502:Varicelloviruses
4477:
4476:
4464:
4463:
4451:
4450:
4449:
4423:
4422:
4410:
4409:
4397:
4396:
4395:
4382:
4381:
4380:
4350:
4166:
3992:
3985:
3979:Papillomaviridae
3815:
3792:Kaposi's sarcoma
3760:Roseola vaccinia
3681:
3661:
3616:Herpetic sycosis
3601:Herpetic whitlow
3589:
3582:
3571:
3560:
3551:
3532:
3525:
3518:
3509:
3368:Varicella zoster
3362:
3355:
3348:
3339:
3327:
3002:
2996:
2990:
2984:
2979:
2978:
2759:
2449:
2443:
2438:
2437:
2427:
2421:
2416:
2415:
2272:
2268:
2213:
2209:
2156:Taxonomy of the
2150:
2143:
2136:
2127:
2122:
2106:
2105:
2103:
2086:(4): 698. 2015.
2072:
2066:
2065:
2037:
2031:
2030:
2028:
2026:
2011:
2005:
2004:
1976:
1970:
1969:
1941:
1935:
1934:
1914:
1908:
1907:
1897:
1865:
1859:
1858:
1856:
1854:
1842:
1836:
1835:
1833:
1831:
1825:
1816:
1810:
1809:
1800: 10542961.
1788:(10): CD008858.
1777:
1771:
1770:
1746:
1740:
1739:
1716:
1710:
1709:
1701:
1695:
1694:
1676:
1667:
1661:
1660:
1632:
1626:
1625:
1615:
1598:(23): 12758–65.
1583:
1577:
1576:
1566:
1534:
1528:
1527:
1517:
1493:
1484:
1483:
1473:
1441:
1435:
1434:
1424:
1384:
1378:
1377:
1367:
1343:
1337:
1336:
1334:
1333:
1317:
1311:
1310:
1300:
1290:
1266:
1260:
1259:
1249:
1217:
1211:
1210:
1200:
1176:
1170:
1169:
1159:
1149:
1125:
1119:
1118:
1108:
1098:
1074:
1068:
1067:
1047:
1041:
1040:
1032:
1023:
1022:
986:
980:
979:
951:
945:
944:
942:
941:
926:
920:
919:
917:
915:
897:
891:
890:
882:
880:
871:. Archived from
857:
678:for chickenpox,
610:
607:
601:
577:
569:
555:circular genomes
511:
508:
502:
478:
470:
277:, including the
70:
69:
44:
30:
21:
4522:
4521:
4517:
4516:
4515:
4513:
4512:
4511:
4487:
4486:
4485:
4480:
4472:
4467:
4459:
4454:
4445:
4444:
4439:
4426:
4418:
4413:
4405:
4400:
4391:
4390:
4385:
4376:
4375:
4370:
4357:
4347:
4342:
4323:Lipschütz ulcer
4293:
4251:
4226:
4191:
4171:Paramyxoviridae
4151:
4122:
4079:
4059:
3988:
3968:
3938:
3914:Milker's nodule
3894:
3846:Monkeypox virus
3798:
3771:
3722:
3677:
3672:
3655:
3650:
3585:
3545:
3539:Skin infections
3536:
3506:
3501:
3485:
3459:
3433:
3387:
3369:
3366:
3336:
3331:
3301:
3226:
3208:
3163:
3138:
3078:
3018:
2992:
2991:
2986:
2985:
2980:
2977:
2976:
2962:
2917:
2887:
2857:
2834:Muromegalovirus
2827:
2764:Cytomegalovirus
2742:
2632:
2542:
2517:
2472:
2439:
2436:
2435:
2417:
2414:
2413:
2395:
2365:
2335:
2300:
2247:
2229:
2196:
2162:
2154:
2117:
2114:
2109:
2074:
2073:
2069:
2039:
2038:
2034:
2024:
2022:
2013:
2012:
2008:
1978:
1977:
1973:
1946:Klin Wochenschr
1943:
1942:
1938:
1916:
1915:
1911:
1867:
1866:
1862:
1852:
1850:
1844:
1843:
1839:
1829:
1827:
1823:
1818:
1817:
1813:
1779:
1778:
1774:
1748:
1747:
1743:
1718:
1717:
1713:
1703:
1702:
1698:
1674:
1669:
1668:
1664:
1634:
1633:
1629:
1585:
1584:
1580:
1536:
1535:
1531:
1495:
1494:
1487:
1456:(18): 9558–65.
1443:
1442:
1438:
1386:
1385:
1381:
1358:(9): 1759–816.
1345:
1344:
1340:
1331:
1329:
1319:
1318:
1314:
1268:
1267:
1263:
1219:
1218:
1214:
1178:
1177:
1173:
1127:
1126:
1122:
1076:
1075:
1071:
1049:
1048:
1044:
1034:
1033:
1026:
997:(11): 1015–28.
988:
987:
983:
953:
952:
948:
939:
937:
928:
927:
923:
913:
911:
899:
898:
894:
878:
876:
859:
858:
854:
850:
828:
793:
772:GlaxoSmithKline
768:subunit vaccine
714:
706:Main articles:
704:
672:
619:common ancestor
611:
605:
602:
595:
578:
567:
561:in the genome.
552:
548:
544:
512:
506:
503:
496:
479:
468:
449:and pentameric
423:
410:Reye's syndrome
366:
326:viral pneumonia
324:(either direct
310:
304:
299:
181:
64:
28:
23:
22:
15:
12:
11:
5:
4520:
4518:
4510:
4509:
4504:
4499:
4489:
4488:
4482:
4481:
4479:
4478:
4465:
4452:
4436:
4434:
4428:
4427:
4425:
4424:
4411:
4398:
4383:
4367:
4365:
4359:
4358:
4353:
4344:
4343:
4341:
4340:
4335:
4330:
4325:
4320:
4315:
4309:
4307:
4303:
4302:
4299:
4298:
4295:
4294:
4292:
4291:
4286:
4281:
4280:
4279:
4274:
4263:
4261:
4258:Picornaviridae
4253:
4252:
4250:
4249:
4244:
4238:
4236:
4228:
4227:
4225:
4224:
4223:
4222:
4216:
4203:
4201:
4193:
4192:
4190:
4189:
4188:
4187:
4176:
4174:
4163:
4157:
4156:
4153:
4152:
4150:
4149:
4148:
4147:
4134:
4132:
4129:Polyomaviridae
4124:
4123:
4121:
4120:
4119:
4118:
4113:
4108:
4100:Parvovirus B19
4095:
4093:
4085:
4084:
4081:
4080:
4078:
4077:
4076:
4075:
4073:Equine sarcoid
4064:
4061:
4060:
4058:
4057:
4052:
4050:Pigmented wart
4047:
4042:
4037:
4032:
4030:Butcher's wart
4027:
4022:
4021:
4020:
4010:
4008:Heck's disease
4005:
3995:
3993:
3982:
3974:
3973:
3970:
3969:
3967:
3966:
3961:
3956:
3946:
3944:
3940:
3939:
3937:
3936:
3931:
3926:
3921:
3916:
3906:
3904:
3896:
3895:
3893:
3892:
3887:
3886:
3885:
3880:
3875:
3870:
3863:Vaccinia virus
3860:
3855:
3854:
3853:
3843:
3842:
3841:
3836:
3825:
3823:
3812:
3804:
3803:
3800:
3799:
3797:
3796:
3795:
3794:
3783:
3781:
3773:
3772:
3770:
3769:
3764:
3763:
3762:
3757:
3738:
3736:
3728:
3727:
3724:
3723:
3721:
3720:
3715:
3710:
3705:
3700:
3695:
3690:
3684:
3682:
3674:
3673:
3671:
3670:
3664:
3662:
3652:
3651:
3649:
3648:
3643:
3638:
3633:
3628:
3626:Genital herpes
3623:
3618:
3613:
3608:
3603:
3598:
3596:Herpes simplex
3592:
3590:
3579:
3568:
3557:
3547:
3546:
3537:
3535:
3534:
3527:
3520:
3512:
3503:
3502:
3500:
3499:
3493:
3491:
3487:
3486:
3484:
3483:
3478:
3476:Zoster vaccine
3473:
3467:
3465:
3461:
3460:
3458:
3457:
3452:
3447:
3441:
3439:
3435:
3434:
3432:
3431:
3426:
3421:
3416:
3411:
3406:
3401:
3395:
3393:
3389:
3388:
3386:
3385:
3383:Varicellovirus
3379:
3377:
3371:
3370:
3367:
3365:
3364:
3357:
3350:
3342:
3333:
3332:
3314:
3311:
3310:
3307:
3306:
3303:
3302:
3300:
3299:
3294:
3289:
3284:
3279:
3274:
3269:
3264:
3259:
3254:
3249:
3244:
3238:
3236:
3228:
3227:
3225:
3224:
3220:
3218:
3210:
3209:
3207:
3206:
3201:
3196:
3191:
3186:
3181:
3175:
3173:
3165:
3164:
3162:
3161:
3156:
3150:
3148:
3140:
3139:
3137:
3136:
3131:
3126:
3121:
3116:
3111:
3106:
3101:
3096:
3090:
3088:
3080:
3079:
3077:
3076:
3071:
3066:
3061:
3056:
3051:
3046:
3041:
3036:
3030:
3028:
3020:
3019:
3017:
3016:
3012:
3010:
2999:
2968:
2967:
2964:
2963:
2961:
2960:
2955:
2950:
2945:
2940:
2935:
2929:
2927:
2919:
2918:
2916:
2915:
2910:
2905:
2899:
2897:
2889:
2888:
2886:
2885:
2880:
2875:
2869:
2867:
2859:
2858:
2856:
2855:
2850:
2845:
2839:
2837:
2829:
2828:
2826:
2825:
2820:
2815:
2810:
2805:
2800:
2795:
2790:
2785:
2780:
2775:
2769:
2767:
2756:
2748:
2747:
2744:
2743:
2741:
2740:
2735:
2730:
2725:
2720:
2715:
2710:
2705:
2700:
2695:
2690:
2685:
2680:
2675:
2670:
2665:
2660:
2655:
2650:
2644:
2642:
2639:Varicellovirus
2634:
2633:
2631:
2630:
2625:
2620:
2615:
2610:
2605:
2600:
2595:
2590:
2585:
2580:
2575:
2570:
2565:
2560:
2554:
2552:
2544:
2543:
2541:
2540:
2535:
2529:
2527:
2519:
2518:
2516:
2515:
2510:
2505:
2500:
2495:
2490:
2484:
2482:
2474:
2473:
2471:
2470:
2465:
2459:
2457:
2446:
2424:
2405:
2404:
2401:
2400:
2397:
2396:
2394:
2393:
2388:
2383:
2377:
2375:
2367:
2366:
2364:
2363:
2358:
2353:
2347:
2345:
2337:
2336:
2334:
2333:
2328:
2323:
2318:
2312:
2310:
2302:
2301:
2299:
2298:
2293:
2288:
2282:
2280:
2265:
2257:
2256:
2253:
2252:
2249:
2248:
2246:
2245:
2241:
2239:
2231:
2230:
2228:
2227:
2223:
2221:
2206:
2198:
2197:
2189:Herviviricetes
2177:Heunggongvirae
2167:
2164:
2163:
2155:
2153:
2152:
2145:
2138:
2130:
2124:
2123:
2113:
2112:External links
2110:
2108:
2107:
2067:
2032:
2006:
1971:
1936:
1909:
1880:(8): 1279–87.
1860:
1837:
1811:
1772:
1761:(RR-4): 1–40.
1741:
1711:
1696:
1662:
1627:
1578:
1549:(3): 1608–22.
1529:
1485:
1436:
1379:
1338:
1312:
1261:
1232:(11): 853–60.
1212:
1191:(7): e529-34.
1171:
1120:
1069:
1042:
1024:
981:
946:
921:
892:
851:
849:
846:
845:
844:
839:
834:
827:
824:
792:
789:
712:zoster vaccine
703:
700:
671:
668:
623:conserved gene
613:
612:
581:
579:
572:
566:
563:
550:
546:
542:
514:
513:
482:
480:
473:
467:
464:
422:
419:
385:sensory nerves
365:
362:
338:nervous system
306:Main article:
303:
300:
298:
295:
240:herpes viruses
205:
204:
203:
202:
196:
190:
189:
183:
182:
175:
173:
169:
168:
165:Varicellovirus
161:
157:
156:
149:
145:
144:
137:
133:
132:
129:Herviviricetes
125:
121:
120:
113:
109:
108:
105:Heunggongvirae
101:
97:
96:
89:
82:
81:
76:
72:
71:
58:
57:
46:
45:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
4519:
4508:
4505:
4503:
4500:
4498:
4495:
4494:
4492:
4475:
4470:
4466:
4462:
4457:
4453:
4448:
4442:
4438:
4437:
4435:
4433:
4429:
4421:
4416:
4412:
4408:
4403:
4399:
4394:
4388:
4384:
4379:
4373:
4369:
4368:
4366:
4364:
4360:
4356:
4351:
4339:
4336:
4334:
4331:
4329:
4326:
4324:
4321:
4319:
4316:
4314:
4311:
4310:
4308:
4304:
4290:
4287:
4285:
4282:
4278:
4275:
4273:
4270:
4269:
4268:
4265:
4264:
4262:
4260:
4259:
4254:
4248:
4245:
4243:
4240:
4239:
4237:
4235:
4234:
4229:
4220:
4217:
4215:
4212:
4211:
4210:
4209:
4208:Rubella virus
4205:
4204:
4202:
4200:
4199:
4198:Matonaviridae
4194:
4186:
4183:
4182:
4181:
4178:
4177:
4175:
4173:
4172:
4167:
4164:
4162:
4158:
4146:
4143:
4142:
4141:
4140:
4136:
4135:
4133:
4131:
4130:
4125:
4117:
4114:
4112:
4109:
4107:
4104:
4103:
4102:
4101:
4097:
4096:
4094:
4092:
4091:
4086:
4074:
4071:
4070:
4069:
4066:
4065:
4062:
4056:
4053:
4051:
4048:
4046:
4045:Verruca plana
4043:
4041:
4038:
4036:
4033:
4031:
4028:
4026:
4023:
4019:
4016:
4015:
4014:
4011:
4009:
4006:
4004:
4000:
3997:
3996:
3994:
3991:
3986:
3983:
3981:
3980:
3975:
3965:
3962:
3960:
3957:
3955:
3951:
3948:
3947:
3945:
3941:
3935:
3932:
3930:
3927:
3925:
3922:
3920:
3917:
3915:
3911:
3908:
3907:
3905:
3903:
3902:
3897:
3891:
3888:
3884:
3881:
3879:
3876:
3874:
3871:
3869:
3866:
3865:
3864:
3861:
3859:
3856:
3852:
3849:
3848:
3847:
3844:
3840:
3837:
3835:
3832:
3831:
3830:
3827:
3826:
3824:
3822:
3821:
3816:
3813:
3811:
3810:
3805:
3793:
3790:
3789:
3788:
3785:
3784:
3782:
3780:
3779:
3774:
3768:
3765:
3761:
3758:
3756:
3753:
3752:
3751:
3750:
3745:
3744:
3740:
3739:
3737:
3735:
3734:
3729:
3719:
3716:
3714:
3711:
3709:
3706:
3704:
3701:
3699:
3696:
3694:
3693:Herpes zoster
3691:
3689:
3686:
3685:
3683:
3680:
3675:
3669:
3666:
3665:
3663:
3660:
3659:
3653:
3647:
3644:
3642:
3639:
3637:
3634:
3632:
3629:
3627:
3624:
3622:
3619:
3617:
3614:
3612:
3609:
3607:
3604:
3602:
3599:
3597:
3594:
3593:
3591:
3588:
3583:
3580:
3578:
3577:
3572:
3569:
3567:
3566:
3565:Herpesviridae
3561:
3558:
3556:
3552:
3548:
3544:
3540:
3533:
3528:
3526:
3521:
3519:
3514:
3513:
3510:
3498:
3495:
3494:
3492:
3488:
3482:
3479:
3477:
3474:
3472:
3469:
3468:
3466:
3462:
3456:
3453:
3451:
3448:
3446:
3443:
3442:
3440:
3436:
3430:
3427:
3425:
3422:
3420:
3417:
3415:
3412:
3410:
3407:
3405:
3404:Herpes zoster
3402:
3400:
3397:
3396:
3394:
3390:
3384:
3381:
3380:
3378:
3376:
3372:
3363:
3358:
3356:
3351:
3349:
3344:
3343:
3340:
3330:
3326:
3321:
3317:
3312:
3298:
3295:
3293:
3290:
3288:
3285:
3283:
3280:
3278:
3275:
3273:
3270:
3268:
3265:
3263:
3260:
3258:
3255:
3253:
3250:
3248:
3245:
3243:
3240:
3239:
3237:
3235:
3234:
3229:
3222:
3221:
3219:
3217:
3216:
3211:
3205:
3202:
3200:
3197:
3195:
3192:
3190:
3187:
3185:
3182:
3180:
3177:
3176:
3174:
3172:
3171:
3166:
3160:
3157:
3155:
3152:
3151:
3149:
3147:
3146:
3141:
3135:
3132:
3130:
3127:
3125:
3122:
3120:
3117:
3115:
3112:
3110:
3107:
3105:
3102:
3100:
3097:
3095:
3092:
3091:
3089:
3087:
3086:
3081:
3075:
3072:
3070:
3067:
3065:
3062:
3060:
3057:
3055:
3052:
3050:
3047:
3045:
3042:
3040:
3037:
3035:
3032:
3031:
3029:
3027:
3026:
3021:
3014:
3013:
3011:
3009:
3008:
3003:
3000:
2995:
2989:
2983:
2975:
2974:
2969:
2959:
2956:
2954:
2951:
2949:
2946:
2944:
2941:
2939:
2936:
2934:
2931:
2930:
2928:
2926:
2925:
2920:
2914:
2911:
2909:
2906:
2904:
2901:
2900:
2898:
2896:
2895:
2890:
2884:
2881:
2879:
2876:
2874:
2871:
2870:
2868:
2866:
2865:
2864:Proboscivirus
2860:
2854:
2851:
2849:
2846:
2844:
2841:
2840:
2838:
2836:
2835:
2830:
2824:
2821:
2819:
2816:
2814:
2811:
2809:
2806:
2804:
2801:
2799:
2796:
2794:
2791:
2789:
2786:
2784:
2781:
2779:
2776:
2774:
2771:
2770:
2768:
2766:
2765:
2760:
2757:
2755:
2754:
2749:
2739:
2736:
2734:
2731:
2729:
2726:
2724:
2721:
2719:
2716:
2714:
2711:
2709:
2706:
2704:
2701:
2699:
2696:
2694:
2691:
2689:
2686:
2684:
2681:
2679:
2676:
2674:
2671:
2669:
2666:
2664:
2661:
2659:
2656:
2654:
2651:
2649:
2646:
2645:
2643:
2641:
2640:
2635:
2629:
2626:
2624:
2621:
2619:
2616:
2614:
2611:
2609:
2606:
2604:
2601:
2599:
2596:
2594:
2591:
2589:
2586:
2584:
2581:
2579:
2576:
2574:
2571:
2569:
2566:
2564:
2561:
2559:
2556:
2555:
2553:
2551:
2550:
2545:
2539:
2536:
2534:
2531:
2530:
2528:
2526:
2525:
2520:
2514:
2511:
2509:
2506:
2504:
2501:
2499:
2496:
2494:
2491:
2489:
2486:
2485:
2483:
2481:
2480:
2475:
2469:
2466:
2464:
2461:
2460:
2458:
2456:
2455:
2450:
2447:
2442:
2434:
2433:
2428:
2425:
2420:
2412:
2411:
2410:Herpesviridae
2406:
2392:
2389:
2387:
2384:
2382:
2379:
2378:
2376:
2374:
2373:
2368:
2362:
2359:
2357:
2354:
2352:
2349:
2348:
2346:
2344:
2343:
2342:Ictalurivirus
2338:
2332:
2329:
2327:
2324:
2322:
2319:
2317:
2314:
2313:
2311:
2309:
2308:
2303:
2297:
2294:
2292:
2289:
2287:
2284:
2283:
2281:
2279:
2278:
2277:Batrachovirus
2273:
2269:
2266:
2264:
2263:
2258:
2243:
2242:
2240:
2238:
2237:
2232:
2225:
2224:
2222:
2220:
2219:
2214:
2210:
2207:
2205:
2204:
2199:
2195:
2194:Herpesvirales
2191:
2190:
2185:
2184:
2183:Peploviricota
2179:
2178:
2173:
2172:
2171:Duplodnaviria
2165:
2161:
2160:
2159:Herpesvirales
2151:
2146:
2144:
2139:
2137:
2132:
2131:
2128:
2120:
2116:
2115:
2111:
2102:
2097:
2093:
2089:
2085:
2081:
2077:
2071:
2068:
2063:
2059:
2055:
2051:
2047:
2043:
2036:
2033:
2021:
2017:
2010:
2007:
2002:
1998:
1994:
1990:
1986:
1982:
1975:
1972:
1967:
1963:
1959:
1955:
1951:
1947:
1940:
1937:
1932:
1928:
1924:
1920:
1913:
1910:
1905:
1901:
1896:
1891:
1887:
1883:
1879:
1875:
1871:
1864:
1861:
1848:
1841:
1838:
1822:
1815:
1812:
1807:
1803:
1799:
1795:
1791:
1787:
1783:
1776:
1773:
1768:
1764:
1760:
1756:
1752:
1745:
1742:
1737:
1733:
1729:
1725:
1721:
1715:
1712:
1707:
1700:
1697:
1692:
1688:
1684:
1680:
1673:
1666:
1663:
1658:
1654:
1650:
1646:
1642:
1638:
1631:
1628:
1623:
1619:
1614:
1609:
1605:
1601:
1597:
1593:
1589:
1582:
1579:
1574:
1570:
1565:
1560:
1556:
1552:
1548:
1544:
1540:
1533:
1530:
1525:
1521:
1516:
1511:
1508:(2): 216–25.
1507:
1503:
1499:
1492:
1490:
1486:
1481:
1477:
1472:
1467:
1463:
1459:
1455:
1451:
1447:
1440:
1437:
1432:
1428:
1423:
1418:
1414:
1410:
1406:
1402:
1398:
1394:
1390:
1383:
1380:
1375:
1371:
1366:
1361:
1357:
1353:
1349:
1342:
1339:
1327:
1323:
1316:
1313:
1308:
1304:
1299:
1294:
1289:
1284:
1281:(3): 361–81.
1280:
1276:
1272:
1265:
1262:
1257:
1253:
1248:
1243:
1239:
1235:
1231:
1227:
1223:
1216:
1213:
1208:
1204:
1199:
1194:
1190:
1186:
1182:
1175:
1172:
1167:
1163:
1158:
1153:
1148:
1143:
1139:
1135:
1131:
1124:
1121:
1116:
1112:
1107:
1102:
1097:
1092:
1088:
1084:
1080:
1073:
1070:
1065:
1061:
1057:
1053:
1046:
1043:
1038:
1031:
1029:
1025:
1020:
1016:
1012:
1008:
1004:
1000:
996:
992:
985:
982:
977:
973:
969:
965:
961:
957:
950:
947:
935:
931:
925:
922:
910:
906:
904:
896:
893:
889:
887:
874:
870:
866:
864:
863:Herpesviridae
856:
853:
847:
843:
840:
838:
835:
833:
830:
829:
825:
823:
821:
818:, a term for
817:
813:
808:
806:
802:
797:
790:
788:
786:
782:
778:
777:intramuscular
773:
769:
765:
761:
759:
754:
749:
747:
743:
739:
735:
731:
727:
723:
719:
713:
709:
701:
699:
697:
693:
689:
685:
681:
677:
669:
667:
665:
664:nonsynonymous
661:
657:
656:mutation rate
652:
650:
646:
641:
639:
635:
631:
626:
624:
620:
609:
606:November 2021
599:
593:
589:
585:
582:This section
580:
576:
571:
570:
564:
562:
560:
556:
540:
536:
532:
529:
525:
521:
510:
507:November 2021
500:
494:
490:
486:
483:This section
481:
477:
472:
471:
465:
463:
460:
456:
452:
448:
444:
440:
436:
432:
431:glycoproteins
428:
420:
418:
416:
411:
406:
402:
398:
394:
390:
386:
381:
379:
374:
371:
363:
361:
359:
355:
351:
347:
343:
342:virus latency
339:
335:
331:
328:or secondary
327:
323:
319:
315:
309:
301:
296:
294:
292:
288:
284:
280:
276:
272:
268:
263:
261:
257:
253:
249:
245:
241:
237:
236:taxonomically
233:
232:
227:
223:
219:
215:
211:
201:
197:
194:
193:
191:
188:
184:
180:
179:
174:
171:
170:
167:
166:
162:
159:
158:
155:
154:
150:
147:
146:
143:
142:
141:Herpesvirales
138:
135:
134:
131:
130:
126:
123:
122:
119:
118:
117:Peploviricota
114:
111:
110:
107:
106:
102:
99:
98:
95:
94:
93:Duplodnaviria
90:
87:
84:
83:
80:
77:
74:
73:
68:
63:
59:
55:
51:
47:
43:
38:
35:
31:
19:
4431:
4362:
4256:
4231:
4206:
4196:
4169:
4137:
4127:
4098:
4090:Parvoviridae
4088:
4013:Genital wart
4003:plantar wart
3977:
3950:Yatapoxvirus
3924:Pseudocowpox
3910:Farmyard pox
3899:
3818:
3807:
3776:
3749:Roseolovirus
3747:
3741:
3731:
3678:
3656:
3574:
3563:
3374:
3233:Rhadinovirus
3231:
3213:
3168:
3145:Manticavirus
3143:
3083:
3023:
3005:
2971:
2924:Roseolovirus
2922:
2892:
2862:
2832:
2762:
2751:
2637:
2549:Simplexvirus
2547:
2522:
2477:
2452:
2430:
2408:
2372:Salmonivirus
2370:
2340:
2307:Cyprinivirus
2305:
2275:
2260:
2234:
2216:
2201:
2193:
2187:
2181:
2175:
2169:
2157:
2083:
2079:
2070:
2048:(1): 55–63.
2045:
2041:
2035:
2023:. Retrieved
2019:
2009:
1984:
1980:
1974:
1949:
1945:
1939:
1925:(3): 60–65.
1922:
1918:
1912:
1877:
1873:
1863:
1851:. Retrieved
1840:
1828:. Retrieved
1814:
1785:
1781:
1775:
1758:
1754:
1744:
1727:
1723:
1714:
1705:
1699:
1682:
1678:
1665:
1640:
1636:
1630:
1595:
1591:
1581:
1546:
1542:
1532:
1505:
1501:
1453:
1449:
1439:
1396:
1392:
1382:
1355:
1351:
1341:
1330:. Retrieved
1325:
1315:
1278:
1274:
1264:
1229:
1225:
1215:
1188:
1184:
1174:
1137:
1133:
1123:
1086:
1082:
1072:
1055:
1051:
1045:
1036:
994:
990:
984:
959:
955:
949:
938:. Retrieved
933:
924:
912:. Retrieved
908:
902:
895:
885:
884:
877:. Retrieved
873:the original
868:
862:
855:
815:
811:
809:
801:Evelyn Nicol
798:
794:
762:
750:
715:
684:valaciclovir
673:
653:
642:
627:
616:
603:
583:
517:
504:
484:
443:nucleocapsid
434:
424:
382:
375:
367:
318:encephalitis
311:
297:Epidemiology
286:
264:
246:. It causes
230:
229:
225:
221:
217:
213:
209:
208:
199:
177:
176:
164:
152:
140:
128:
116:
104:
92:
85:
75:(unranked):
53:
33:
4387:Wikispecies
4233:Togaviridae
3329:Wikispecies
3215:Patagivirus
2236:Ostreavirus
1853:October 30,
1830:16 November
1685:(12): 212.
1643:(1): 9–22.
1035:Tortora G.
781:immunogenic
702:Vaccination
696:intravenous
690:(ZIG), and
680:famciclovir
495:is useful..
4497:Chickenpox
4491:Categories
4277:Herpangina
3890:Buffalopox
3809:Poxviridae
3688:Chickenpox
3464:Prevention
3450:Vidarabine
3399:Chickenpox
3316:Unassigned
3170:Percavirus
3007:Bossavirus
2524:Scutavirus
2479:Mardivirus
1332:2021-06-14
1089:(1): 170.
940:2017-10-10
848:References
692:vidarabine
660:synonymous
638:sequencing
535:base pairs
522:was first
451:capsomeres
421:Morphology
346:trigeminal
344:), in the
334:bronchitis
314:chickenpox
302:Chickenpox
287:reactivate
4447:Q24808715
4306:Ungrouped
4161:RNA virus
3851:Monkeypox
3631:Cold sore
3555:DNA virus
3481:Pox party
3445:Aciclovir
3438:Treatment
3085:Macavirus
2894:Quwivirus
2454:Iltovirus
2218:Aurivirus
1399:: 351–6.
1226:Neurology
934:canada.ca
914:9 January
879:9 January
812:varicella
738:Australia
676:acyclovir
670:Treatment
645:genotypes
598:talk page
565:Evolution
524:sequenced
499:talk page
447:hexameric
322:pneumonia
289:to cause
172:Species:
100:Kingdom:
4441:Wikidata
4420:11460001
4407:46699975
4372:Wikidata
3868:Vaccinia
3839:Alastrim
3834:Smallpox
3392:Diseases
2908:MschBHV1
2062:12118846
2020:Medscape
1966:11118674
1931:11867004
1904:25371534
1806:37781954
1767:17585291
1691:22456121
1622:17898056
1573:22130537
1524:19019403
1502:Virology
1480:22761371
1431:23183312
1256:18332343
1207:23566589
1166:26002038
1115:23574765
1064:18528318
1011:17945155
976:17682626
826:See also
820:smallpox
764:Shingrix
758:Cochrane
753:Zostavax
592:25926648
493:20225013
439:envelope
370:shingles
364:Shingles
291:shingles
187:Synonyms
148:Family:
112:Phylum:
4214:Rubella
4185:Measles
3954:Tanapox
3934:Sealpox
3829:Variola
3658:B virus
3543:viruses
3194:MusHV-1
3154:PhaHV-1
3039:CeHV-14
3034:CalHV-3
2513:SpAHV-1
2381:SalHV-1
2351:AciHV-2
2316:AngHV-1
2101:4378502
2025:Sep 19,
2001:4139526
1895:4371767
1736:8668119
1657:8145260
1613:2169114
1564:3264370
1471:3446551
1422:3594394
1401:Bibcode
1374:3018124
1307:8809466
1247:2938740
1157:4493830
1140:: 215.
1106:3637114
1019:6691444
816:variola
791:History
722:Varivax
718:vaccine
539:isomers
466:Genomes
445:of 162
435:latency
415:aspirin
275:neurons
267:tonsils
260:species
160:Genus:
136:Order:
124:Class:
56:virion
3858:Cowpox
3820:Ortho.
3778:Gamma.
3576:Alpha.
3297:SaHV-2
3287:MuHV-4
3267:McHV-5
3257:CrHV-2
3252:BoHV-4
3242:AtHV-2
3223:VeHV-3
3204:VeHV-1
3199:PhHV-3
3189:FeHV-1
3159:VoHV-1
3124:SuHV-3
3119:OvHV-2
3114:HiHV-1
3109:CpHV-2
3104:BoHV-6
3094:AlHV-1
3074:PoHV-2
3069:PaHV-1
3064:PnHV-1
3054:McHV-4
3044:GoHV-1
3015:DeHV-1
2994:SgHV-1
2988:PhHV-2
2958:SuHV-2
2953:MuHV-3
2948:McHV-9
2933:HHV-6A
2913:TuHV-1
2903:CaHV-2
2873:ElHV-1
2843:MuHV-1
2823:SaHV-4
2813:PaHV-3
2808:PnHV-2
2803:MnHV-1
2793:McHV-3
2783:CeHV-5
2778:CbHV-1
2773:AoHV-1
2738:SuHV-1
2733:PhHV-1
2728:MoHV-1
2718:FeHV-1
2678:CvHV-1
2673:CeHV-9
2668:CpHV-1
2663:CaHV-1
2658:BuHV-1
2648:BoHV-1
2628:SaHV-1
2623:PtHV-1
2618:PaHV-2
2613:PnHV-3
2603:MaHV-1
2588:McHV-1
2583:LeHV-4
2568:CeHV-2
2563:BoHV-2
2558:AtHV-1
2538:TeHV-3
2533:ChHV-5
2508:MeHV-1
2498:GaHV-2
2493:CoHV-1
2488:AnHV-1
2468:PsHV-1
2463:GaHV-1
2441:ChHV-6
2419:IgHV-2
2356:IcHV-1
2321:CyHV-1
2286:RaHV-1
2244:OsHV-1
2226:AbHV-1
2098:
2060:
1999:
1981:Lancet
1964:
1929:
1902:
1892:
1804:
1765:
1734:
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1655:
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630:clades
590:
528:duplex
520:genome
491:
397:stroke
332:), or
4474:10335
4461:3MT72
4415:IRMNG
4378:Q6868
4018:giant
3943:Other
3901:Para.
3733:Beta.
3490:Other
3262:HHV-8
3179:EHV-2
3049:HHV-4
2982:EHV-7
2788:HHV-5
2723:HHV-3
2693:EHV-1
2573:HHV-1
2192:>
2186:>
2180:>
2174:>
1962:S2CID
1824:(PDF)
1675:(PDF)
1015:S2CID
766:is a
634:India
549:and I
242:that
228:) or
222:HHV-3
86:Realm
79:Virus
52:of a
4469:NCBI
3999:Wart
3320:ICTV
2058:PMID
2027:2022
1997:PMID
1927:PMID
1900:PMID
1855:2017
1832:2018
1802:PMID
1786:2023
1763:PMID
1732:PMID
1687:PMID
1653:PMID
1618:PMID
1569:PMID
1520:PMID
1476:PMID
1427:PMID
1370:PMID
1303:PMID
1252:PMID
1203:PMID
1162:PMID
1111:PMID
1060:PMID
1007:PMID
972:PMID
916:2019
881:2019
710:and
662:and
658:for
654:The
588:PMID
518:The
489:PMID
348:and
226:HHV3
4456:CoL
4402:EoL
4180:MeV
3990:HPV
3929:Orf
3679:VZV
3587:HSV
3322:––
2096:PMC
2088:doi
2050:doi
1989:doi
1954:doi
1890:PMC
1882:doi
1878:211
1798:PMC
1790:doi
1645:doi
1641:238
1608:PMC
1600:doi
1559:PMC
1551:doi
1510:doi
1506:383
1466:PMC
1458:doi
1417:PMC
1409:doi
1360:doi
1293:PMC
1283:doi
1242:PMC
1234:doi
1193:doi
1152:PMC
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1101:PMC
1091:doi
999:doi
964:doi
531:DNA
455:DNA
214:VZV
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