39:
66:
Notably, in people who do not have the genetic disorder hypobetalipoproteinemia, a very low cholesterol level (less than 100 mg/dl) may be a marker for poor nutrition, wasting disease, cancer, hyperthyroidism, and liver disease. In 1997 a study showed that
Japanese Centenarians had tenfold
400:
385:
500:
601:
236:
Young SG, Hubl ST, Chappell DA, et al. (June 1989). "Familial hypobetalipoproteinemia associated with a mutant species of apolipoprotein B (B-46)".
493:
83:
109:
Typically in hypobetalipoproteinemia, plasma cholesterol levels will be around 80–120 mg/dL, LDL cholesterol will be around 50–80 mg/dL.
708:
486:
415:
547:
513:
562:
272:
Tarugi P, Averna M, Di Leo E, et al. (December 2007). "Molecular diagnosis of hypobetalipoproteinemia: an ENID review".
656:
634:
567:
552:
542:
94:
629:
687:
509:
682:
59:, below the 5th percentile. The patient can have hypobetalipoproteinemia and simultaneously have high levels of
593:
426:
557:
466:
624:
537:
533:
87:
38:
584:
404:
478:
177:
677:
348:
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289:
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169:
27:
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159:
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76:
56:
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60:
52:
164:
139:
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409:
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32:
517:
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181:
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672:
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307:
Zamel, Rola; Khan, Razi; Pollex, Rebecca L.; Hegele, Robert A. (2008-07-08).
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173:
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574:
461:
377:
389:
98:
420:
482:
309:"Abetalipoproteinemia: two case reports and literature review"
67:
increase of hypobetalipoproteinemia compared with controls.
140:"Familial hypobetalipoproteinemia: genetics and metabolism"
367:
665:
647:
615:
592:
583:
524:
441:
371:
121:in infants and children has shown to be effective.
26:
21:
602:Lecithin cholesterol acyltransferase deficiency
494:
8:
197:"Familial hypobetalipoproteinemia: a review"
75:One form is thought to be caused by mutated
589:
548:Familial apoprotein CII deficiency/Type Ib
501:
487:
479:
368:
51:is a disorder consisting of low levels of
37:
18:
342:
324:
212:
163:
563:Familial dysbetalipoproteinemia/Type III
84:microsomal triglyceride transfer protein
138:Schonfeld G, Lin X, Yue P (June 2005).
130:
553:Familial hypercholesterolemia/Type IIa
568:Familial hypertriglyceridemia/Type IV
543:Lipoprotein lipase deficiency/Type Ia
286:10.1016/j.atherosclerosis.2007.05.003
7:
14:
313:Orphanet Journal of Rare Diseases
688:APOA1 familial renal amyloidosis
558:Combined hyperlipidemia/Type IIb
82:Another form is associated with
1:
635:Chylomicron retention disease
95:chylomicron retention disease
594:Hypoalphalipoproteinemia/HDL
630:Apolipoprotein B deficiency
617:Hypobetalipoproteinemia/LDL
251:10.1056/NEJM198906153202407
725:
709:Lipid metabolism disorders
214:10.1194/jlr.R300002-JLR200
97:(CRD), is associated with
657:Barraquer–Simons syndrome
156:10.1007/s00018-005-4473-0
195:Schonfeld G (May 2003).
49:Hypobetalipoproteinemia
22:Hypobetalipoproteinemia
575:Xanthoma/Xanthomatosis
326:10.1186/1750-1172-3-19
625:Abetalipoproteinemia
538:Hypertriglyceridemia
534:Hypercholesterolemia
117:Early high doses of
88:abetalipoproteinemia
585:Hypolipoproteinemia
144:Cell. Mol. Life Sci
683:Lipoid proteinosis
442:External resources
696:
695:
678:Adiposis dolorosa
643:
642:
476:
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46:
45:
16:Medical condition
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590:
514:lipid metabolism
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239:N. Engl. J. Med.
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77:apolipoprotein B
57:apolipoprotein B
42:
41:
19:
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719:
718:
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607:Tangier disease
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437:
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380:
366:
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274:Atherosclerosis
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245:(24): 1604–10.
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194:
193:
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137:
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115:
107:
73:
61:HDL cholesterol
53:LDL cholesterol
36:
17:
12:
11:
5:
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526:Hyperlipidemia
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373:
372:Classification
365:
364:External links
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187:
150:(12): 1372–8.
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93:A third form,
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44:
43:
30:
24:
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15:
13:
10:
9:
6:
4:
3:
2:
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689:
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664:
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649:Lipodystrophy
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628:
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283:
280:(2): e19–27.
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256:
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207:(5): 878–83.
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86:which causes
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78:
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68:
64:
62:
58:
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50:
40:
34:
33:Endocrinology
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29:
25:
20:
616:
518:dyslipidemia
510:Inborn error
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201:J. Lipid Res
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147:
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133:
116:
108:
92:
81:
74:
65:
48:
47:
673:Lipomatosis
125:References
451:eMedicine
335:1750-1172
119:vitamin E
113:Treatment
105:Diagnosis
28:Specialty
703:Category
462:Orphanet
456:med/1117
353:18611256
294:17570373
223:12639976
174:15818469
165:11139194
432:D006995
344:2467409
259:2725600
182:9054743
421:615558
351:
341:
333:
319:: 19.
292:
257:
221:
180:
172:
162:
71:Causes
35:
666:Other
467:31154
410:272.5
395:E78.6
178:S2CID
99:SARA2
512:of
427:MeSH
416:OMIM
405:9-CM
349:PMID
331:ISSN
290:PMID
255:PMID
219:PMID
170:PMID
401:ICD
386:ICD
339:PMC
321:doi
282:doi
278:195
247:doi
243:320
209:doi
160:PMC
152:doi
55:or
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390:10
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205:44
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148:62
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90:.
79:.
63:.
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502:e
495:t
488:v
403:-
388:-
378:D
355:.
323::
317:3
296:.
284::
261:.
249::
225:.
211::
184:.
154::
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