Knowledge (XXG)

HAS1

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242: 219: 116: 141: 493: 248: 147: 2927: 1458:"Characterization of hyaluronan synthase expression and hyaluronan synthesis in bone marrow mesenchymal progenitor cells: predominant expression of HAS1 mRNA and up-regulated hyaluronan synthesis in bone marrow cells derived from multiple myeloma patients" 1776:
Campo GM, Avenoso A, Campo S, et al. (2007). "TNF-alpha, IFN-gamma, and IL-1beta modulate hyaluronan synthase expression in human skin fibroblasts: synergistic effect by concomital treatment with FeSO4 plus ascorbate".
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Suzuki K, Yamamoto T, Usui T, et al. (2004). "Expression of hyaluronan synthase in intraocular proliferative diseases: regulation of expression in human vascular endothelial cells by transforming growth factor-beta".
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Spicer AP, Seldin MF, Olsen AS, Brown N, Wells DE, Doggett NA, Itano N, Kimata K, Inazawa J, McDonald JA (Jul 1997). "Chromosomal localization of the human and mouse hyaluronan synthase genes".
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Kao JJ (2007). "The NF-kappaB inhibitor pyrrolidine dithiocarbamate blocks IL-1beta induced hyaluronan synthase 1 (HAS1) mRNA transcription, pointing at NF-kappaB dependence of the gene HAS1".
2445: 2321: 2112: 1030:. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound 255: 154: 1677:"Adenovirus-mediated gene transfer of mutated IkappaB kinase and IkappaBalpha reveal NF-kappaB-dependent as well as NF-kappaB-independent pathways of HAS1 activation" 2426: 1423:"Manipulation of hyaluronan synthase expression in prostate adenocarcinoma cells alters pericellular matrix retention and adhesion to bone marrow endothelial cells" 2494: 1943: 2603: 1316:"Analysis of cell-growth-phase-related variations in hyaluronate synthase activity of isolated plasma-membrane fractions of cultured human skin fibroblasts" 2573: 1074:. HAS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant 726: 707: 77: 2248: 2243: 1544:
Adamia S, Crainie M, Kriangkum J, et al. (2003). "Abnormal expression of hyaluronan synthases in patients with Waldenstrom's macroglobulimenia".
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Grskovic B, Pollaschek C, Mueller MM, Stuhlmeier KM (2006). "Expression of hyaluronan synthase genes in umbilical cord blood stem/progenitor cells".
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at the inner surface of the plasma membrane, and the chains are extruded via ABC-transporter into the extracellular space.
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Yabushita H, Kishida T, Fusano K, et al. (2005). "Role of hyaluronan and hyaluronan synthase in endometrial cancer".
1605:"Intronic splicing of hyaluronan synthase 1 (HAS1): a biologically relevant indicator of poor outcome in multiple myeloma" 2917: 1113: 2039: 57: 2024: 254: 153: 2464: 2787: 1285:
Spicer AP, Nguyen TK (1999). "Mammalian hyaluronan synthases: investigation of functional relationships in vivo".
2903: 2890: 2877: 2864: 2851: 2838: 2825: 2589: 2481: 2394: 2029: 1969: 247: 146: 2797: 2751: 2694: 2034: 2007: 1960: 771: 65: 2699: 2524: 2087: 752: 2002: 1079: 2720: 2639: 2568: 2054: 2044: 129: 2792: 2436: 2263: 1997: 1504: 1059: 1027: 1892:
Kyossev Z, Weigel PH (2007). "An enzyme capture assay for analysis of active hyaluronan synthases".
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synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the
89: 1493:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 917: 896: 866: 845: 2952: 2593: 2019: 1921: 1909: 1880: 1845: 1794: 1756: 1727: 1698: 1663: 1634: 1591: 1561: 1532: 1479: 1444: 1409: 1374: 1345: 1302: 1262: 1204: 1083: 1054:. Changes in the serum concentration of HA are associated with inflammatory and degenerative 37: 1046:, and provision of a matrix through which cells can migrate. HA is actively produced during 2735: 2730: 2704: 2632: 2431: 2418: 2062: 2012: 1901: 1870: 1835: 1827: 1786: 1748: 1719: 1688: 1655: 1624: 1616: 1583: 1553: 1522: 1512: 1469: 1434: 1399: 1366: 1335: 1327: 1294: 1252: 1196: 334: 265: 209: 164: 2303: 2298: 2782: 2766: 2679: 2450: 1019: 492: 309: 85: 1508: 1241:"Hyaluronan export by the ABC transporter MRP5 and its modulation by intracellular cGMP" 2931: 2820: 2761: 1840: 1815: 1629: 1604: 1340: 1315: 1088: 1023: 1527: 1492: 641: 636: 631: 626: 621: 616: 611: 606: 590: 585: 580: 575: 570: 554: 549: 544: 539: 534: 2941: 2725: 2684: 2455: 1992: 1055: 1047: 521: 1806: 1768: 2674: 327: 106: 69: 1723: 93: 2898: 2833: 2669: 1952: 1816:"Large-scale mapping of human protein-protein interactions by mass spectrometry" 1752: 1174:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Itano N, Kimata K (1996). "Molecular cloning of human hyaluronan synthase".
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and tissue repair to provide a framework for ingrowth of blood vessels and
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It serves a variety of functions, including space filling, lubrication of
981: 976: 1659: 1031: 965: 816: 797: 2613: 2471: 2204: 2199: 2194: 2189: 2184: 2152: 2076: 1831: 1298: 783: 738: 1331: 2885: 2655: 2409: 2179: 2174: 2169: 2164: 2159: 2147: 2142: 2137: 2132: 2127: 2122: 2117: 2105: 2100: 2095: 1043: 1000: 949: 693: 1070:, and overexpression of HA receptors has been correlated with tumor 2859: 2561: 2556: 2529: 2380: 2331: 2326: 1062:. In addition, the interaction of HA with the leukocyte receptor 1859:"Involvement of hyaluronan in regulation of fibroblast phenotype" 656: 652: 2375: 2370: 2365: 2360: 2355: 2350: 2343: 2338: 2293: 2288: 2283: 2278: 2273: 2268: 2258: 2253: 2225: 2220: 1388:"Functional cloning of the cDNA for a human hyaluronan synthase" 1063: 1007: 61: 2628: 2073:
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase
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B-N-acetylglucosaminyl-glycopeptide b-1,4-galactosyltransferase
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cellular response to platelet-derived growth factor stimulus
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Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
2624: 317: 1092:, and a recently described murine hyaluronan synthase. 2322:
Dolichyl-phosphate-mannose-protein mannosyltransferase
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Simpson MA, Wilson CM, Furcht LT, et al. (2002).
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Shyjan AM, Heldin P, Butcher EC, et al. (1996).
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Calabro A, Oken MM, Hascall VC, Masellis AM (2002).
2811: 2775: 2744: 2713: 2662: 2588: 2544: 2513: 2480: 2417: 2408: 2393: 2312: 2234: 2086: 2053: 1983: 1968: 1857:Meran S, Thomas D, Stephens P, et al. (2007). 1603:Adamia S, Reiman T, Crainie M, et al. (2005). 910: 885: 859: 834: 1130: 1128: 1126: 1109: 1107: 1105: 637:extracellular polysaccharide biosynthetic process 264: 163: 1814:Ewing RM, Chu P, Elisma F, et al. (2007). 16:Protein-coding gene in the species Homo sapiens 2495:Hypoxanthine-guanine phosphoribosyltransferase 1135:GRCm38: Ensembl release 89: ENSMUSG00000003665 2640: 1937: 1239:Schulz T, Schumacher U, Prehm P (July 2007). 8: 2604:Beta-galactoside alpha-2,6-sialyltransferase 2574:Indolylacetylinositol arabinosyltransferase 1114:GRCh38: Ensembl release 89: ENSG00000105509 1022:(HA) is a high molecular weight unbranched 612:negative regulation of fibroblast migration 2647: 2633: 2625: 2414: 2405: 1980: 1944: 1930: 1922: 1066:is important in tissue-specific homing by 667: 517: 305: 204: 101: 1874: 1839: 1692: 1628: 1526: 1516: 1473: 1438: 1403: 1339: 1256: 1226:"Entrez Gene: HAS1 hyaluronan synthase 1" 1220: 1218: 2922: 1101: 2609:Monosialoganglioside sialyltransferase 2446:NAD(P):arginine ADP-ribosyltransferase 2427:NAD:diphthamide ADP-ribosyltransferase 632:glycosaminoglycan biosynthetic process 18: 586:integral component of plasma membrane 269: 230: 225: 168: 127: 122: 7: 1675:Stuhlmeier KM, Pollaschek C (2006). 907: 882: 856: 831: 807: 788: 762: 743: 717: 698: 487: 405: 343: 322: 14: 2490:Adenine phosphoribosyltransferase 1003:that in humans is encoded by the 2925: 2500:Uracil phosphoribosyltransferase 491: 253: 246: 240: 217: 152: 145: 139: 114: 2521:Purine nucleoside phosphorylase 617:hyaluronan biosynthetic process 2505:Amidophosphoribosyltransferase 576:integral component of membrane 502:More reference expression data 471:More reference expression data 1: 1359:Biochem. Biophys. Res. Commun 627:extracellular matrix assembly 238: 137: 2948:Genes on human chromosome 19 2040:Ceramide glucosyltransferase 1724:10.1016/j.bbagen.2006.02.002 1497:Proc. Natl. Acad. Sci. U.S.A 1078:to the hasA gene product of 545:hyaluronan synthase activity 535:glycosyltransferase activity 48:, HAS, hyaluronan synthase 1 1753:10.1016/j.exger.2006.04.003 2969: 2465:Poly ADP ribose polymerase 1621:10.1182/blood-2004-10-3825 1475:10.1182/blood-2002-01-0030 2803:Michaelis–Menten kinetics 2482:Phosphoribosyltransferase 1791:10.1007/s11010-006-9230-7 1588:10.1016/j.jjo.2003.09.001 1170:"Mouse PubMed Reference:" 1152:"Human PubMed Reference:" 980: 975: 971: 964: 948: 929: 914: 889: 878: 863: 838: 827: 814: 810: 795: 791: 782: 769: 765: 750: 746: 737: 724: 720: 705: 701: 692: 677: 670: 666: 650: 555:identical protein binding 520: 516: 499: 490: 481: 468: 417: 408: 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 2695:Diffusion-limited enzyme 2035:1,3-Beta-glucan synthase 1906:10.1016/j.ab.2007.08.025 1405:10.1074/jbc.271.38.23395 942:Chr 17: 18.06 – 18.08 Mb 935:Chr 19: 51.71 – 51.72 Mb 271:17 A3.2|17 10.53 cM 2525:Thymidine phosphorylase 1558:10.1053/sonc.2003.50042 1086:synthetase (DG42) from 2419:ADP-ribosyltransferase 1876:10.1074/jbc.M700773200 1712:Biochim. Biophys. Acta 1694:10.1074/jbc.M503374200 1518:10.1073/pnas.242603899 1440:10.1074/jbc.M110069200 1371:10.1006/bbrc.1996.0827 1258:10.1074/jbc.M700915200 1201:10.1006/geno.1997.4696 1080:Streptococcus pyogenes 2788:Eadie–Hofstee diagram 2721:Allosteric regulation 2569:Arabinosyltransferase 2045:N-glycosyltransferase 395:middle temporal gyrus 232:Chromosome 17 (mouse) 130:Chromosome 19 (human) 2798:Lineweaver–Burk plot 2437:Pseudomonas exotoxin 1957:glycosyltransferases 1660:10.3892/or.13.6.1101 1060:rheumatoid arthritis 1028:extracellular matrix 540:transferase activity 441:facial motor nucleus 2212:Hyaluronan synthase 1509:2002PNAS...9916899M 1287:Biochem. Soc. Trans 453:submandibular gland 371:germinal epithelium 2757:Enzyme superfamily 2690:Enzyme promiscuity 2552:Xylosyltransferase 2025:Debranching enzyme 1832:10.1038/msb4100134 1779:Mol. Cell. Biochem 1576:Jpn. J. Ophthalmol 1299:10.1042/bst0270109 1251:(29): 20999–1004. 772:ENSMUSG00000003665 600:Biological process 564:Cellular component 528:Molecular function 2913: 2912: 2622: 2621: 2584: 2583: 2540: 2539: 2389: 2388: 2020:Glycogen synthase 1503:(26): 16899–903. 1332:10.1042/bj2370333 1084:glycosaminoglycan 991: 990: 987: 986: 960: 959: 925: 924: 904: 903: 874: 873: 853: 852: 823: 822: 804: 803: 778: 777: 759: 758: 733: 732: 714: 713: 662: 661: 512: 511: 508: 507: 477: 476: 464: 463: 402: 401: 387:synovial membrane 300: 299: 199: 198: 2960: 2930: 2929: 2921: 2793:Hanes–Woolf plot 2736:Enzyme activator 2731:Enzyme inhibitor 2705:Enzyme catalysis 2649: 2642: 2635: 2626: 2432:Diphtheria toxin 2415: 2406: 2063:Lactose synthase 2030:Branching enzyme 1981: 1946: 1939: 1932: 1923: 1917: 1888: 1878: 1869:(35): 25687–97. 1853: 1843: 1810: 1772: 1735: 1706: 1696: 1687:(52): 42766–73. 1671: 1642: 1632: 1599: 1569: 1540: 1530: 1520: 1487: 1477: 1452: 1442: 1417: 1407: 1382: 1353: 1343: 1310: 1271: 1270: 1260: 1236: 1230: 1229: 1222: 1213: 1212: 1184: 1178: 1177: 1166: 1160: 1159: 1148: 1142: 1132: 1121: 1111: 973: 972: 944: 937: 920: 908: 899: 883: 879:RefSeq (protein) 869: 857: 848: 832: 808: 789: 763: 744: 718: 699: 668: 518: 504: 495: 488: 473: 429:genital tubercle 413: 411:Top expressed in 406: 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 94:HAS1 - orthologs 47: 40: 19: 2968: 2967: 2963: 2962: 2961: 2959: 2958: 2957: 2938: 2937: 2936: 2924: 2916: 2914: 2909: 2821:Oxidoreductases 2807: 2783:Enzyme kinetics 2771: 2767:List of enzymes 2740: 2709: 2680:Catalytic triad 2658: 2653: 2623: 2618: 2595: 2580: 2536: 2509: 2476: 2451:Pertussis toxin 2400: 2385: 2308: 2230: 2082: 2049: 1975: 1964: 1950: 1920: 1891: 1856: 1820:Mol. Syst. Biol 1813: 1785:(1–2): 169–78. 1775: 1738: 1709: 1674: 1645: 1615:(12): 4836–44. 1602: 1572: 1543: 1490: 1455: 1433:(12): 10050–7. 1420: 1398:(38): 23395–9. 1385: 1356: 1314:Mian N (1987). 1313: 1284: 1280: 1278:Further reading 1275: 1274: 1238: 1237: 1233: 1224: 1223: 1216: 1186: 1185: 1181: 1168: 1167: 1163: 1150: 1149: 1145: 1133: 1124: 1112: 1103: 1098: 1040: 1020:hyaluronic acid 1016: 982:View/Edit Mouse 977:View/Edit Human 940: 933: 930:Location (UCSC) 916: 895: 891: 865: 844: 840: 753:ENSG00000105509 646: 595: 581:plasma membrane 559: 550:protein binding 500: 469: 460: 457:ascending aorta 455: 451: 447: 443: 439: 435: 431: 427: 423: 409: 398: 393: 389: 385: 381: 377: 373: 369: 365: 363:parietal pleura 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 2966: 2964: 2956: 2955: 2950: 2940: 2939: 2935: 2934: 2911: 2910: 2908: 2907: 2894: 2881: 2868: 2855: 2842: 2829: 2815: 2813: 2809: 2808: 2806: 2805: 2800: 2795: 2790: 2785: 2779: 2777: 2773: 2772: 2770: 2769: 2764: 2759: 2754: 2748: 2746: 2745:Classification 2742: 2741: 2739: 2738: 2733: 2728: 2723: 2717: 2715: 2711: 2710: 2708: 2707: 2702: 2697: 2692: 2687: 2682: 2677: 2672: 2666: 2664: 2660: 2659: 2654: 2652: 2651: 2644: 2637: 2629: 2620: 2619: 2617: 2616: 2611: 2606: 2600: 2598: 2586: 2585: 2582: 2581: 2579: 2578: 2577: 2576: 2566: 2565: 2564: 2559: 2548: 2546: 2542: 2541: 2538: 2537: 2535: 2534: 2533: 2532: 2517: 2515: 2511: 2510: 2508: 2507: 2502: 2497: 2492: 2486: 2484: 2478: 2477: 2475: 2474: 2468: 2467: 2461: 2460: 2459: 2458: 2453: 2442: 2441: 2440: 2439: 2434: 2423: 2421: 2412: 2403: 2391: 2390: 2387: 2386: 2384: 2383: 2378: 2373: 2368: 2363: 2358: 2353: 2347: 2346: 2341: 2336: 2335: 2334: 2329: 2318: 2316: 2310: 2309: 2307: 2306: 2301: 2296: 2291: 2286: 2281: 2276: 2271: 2266: 2261: 2256: 2251: 2246: 2240: 2238: 2232: 2231: 2229: 2228: 2223: 2218: 2208: 2207: 2202: 2197: 2192: 2187: 2182: 2177: 2172: 2167: 2162: 2156: 2155: 2150: 2145: 2140: 2135: 2130: 2125: 2120: 2115: 2109: 2108: 2103: 2098: 2092: 2090: 2084: 2083: 2081: 2080: 2070: 2065: 2059: 2057: 2051: 2050: 2048: 2047: 2042: 2037: 2032: 2027: 2022: 2017: 2016: 2015: 2010: 2005: 2000: 1989: 1987: 1978: 1966: 1965: 1951: 1949: 1948: 1941: 1934: 1926: 1919: 1918: 1889: 1854: 1811: 1773: 1736: 1707: 1672: 1643: 1600: 1570: 1541: 1488: 1468:(7): 2578–85. 1453: 1418: 1383: 1354: 1311: 1281: 1279: 1276: 1273: 1272: 1231: 1214: 1179: 1161: 1143: 1122: 1100: 1099: 1097: 1094: 1089:Xenopus laevis 1039: 1036: 1024:polysaccharide 1018:Hyaluronan or 1015: 1012: 989: 988: 985: 984: 979: 969: 968: 962: 961: 958: 957: 955: 953: 946: 945: 938: 931: 927: 926: 923: 922: 912: 911: 905: 902: 901: 887: 886: 880: 876: 875: 872: 871: 861: 860: 854: 851: 850: 836: 835: 829: 825: 824: 821: 820: 812: 811: 805: 802: 801: 793: 792: 786: 780: 779: 776: 775: 767: 766: 760: 757: 756: 748: 747: 741: 735: 734: 731: 730: 722: 721: 715: 712: 711: 703: 702: 696: 690: 689: 684: 679: 675: 674: 664: 663: 660: 659: 648: 647: 645: 644: 639: 634: 629: 624: 619: 614: 609: 603: 601: 597: 596: 594: 593: 588: 583: 578: 573: 567: 565: 561: 560: 558: 557: 552: 547: 542: 537: 531: 529: 525: 524: 514: 513: 510: 509: 506: 505: 497: 496: 485: 479: 478: 475: 474: 466: 465: 462: 461: 459: 458: 454: 450: 446: 442: 438: 434: 433:tail of embryo 430: 426: 422: 418: 415: 414: 403: 400: 399: 397: 396: 392: 388: 384: 380: 379:synovial joint 376: 372: 368: 364: 360: 356: 353: 352: 340: 339: 331: 320: 314: 313: 310:RNA expression 302: 301: 298: 297: 289: 285: 284: 276: 273: 268: 262: 261: 252: 245: 239: 235: 234: 229: 223: 222: 214: 213: 201: 200: 197: 196: 188: 184: 183: 175: 172: 167: 161: 160: 151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2965: 2954: 2951: 2949: 2946: 2945: 2943: 2933: 2928: 2923: 2919: 2905: 2901: 2900: 2895: 2892: 2888: 2887: 2882: 2879: 2875: 2874: 2869: 2866: 2862: 2861: 2856: 2853: 2849: 2848: 2843: 2840: 2836: 2835: 2830: 2827: 2823: 2822: 2817: 2816: 2814: 2810: 2804: 2801: 2799: 2796: 2794: 2791: 2789: 2786: 2784: 2781: 2780: 2778: 2774: 2768: 2765: 2763: 2762:Enzyme family 2760: 2758: 2755: 2753: 2750: 2749: 2747: 2743: 2737: 2734: 2732: 2729: 2727: 2726:Cooperativity 2724: 2722: 2719: 2718: 2716: 2712: 2706: 2703: 2701: 2698: 2696: 2693: 2691: 2688: 2686: 2685:Oxyanion hole 2683: 2681: 2678: 2676: 2673: 2671: 2668: 2667: 2665: 2661: 2657: 2650: 2645: 2643: 2638: 2636: 2631: 2630: 2627: 2615: 2612: 2610: 2607: 2605: 2602: 2601: 2599: 2597: 2591: 2587: 2575: 2572: 2571: 2570: 2567: 2563: 2560: 2558: 2555: 2554: 2553: 2550: 2549: 2547: 2543: 2531: 2528: 2527: 2526: 2522: 2519: 2518: 2516: 2512: 2506: 2503: 2501: 2498: 2496: 2493: 2491: 2488: 2487: 2485: 2483: 2479: 2473: 2470: 2469: 2466: 2463: 2462: 2457: 2456:Cholera toxin 2454: 2452: 2449: 2448: 2447: 2444: 2443: 2438: 2435: 2433: 2430: 2429: 2428: 2425: 2424: 2422: 2420: 2416: 2413: 2411: 2407: 2404: 2402: 2396: 2392: 2382: 2379: 2377: 2374: 2372: 2369: 2367: 2364: 2362: 2359: 2357: 2354: 2352: 2349: 2348: 2345: 2342: 2340: 2337: 2333: 2330: 2328: 2325: 2324: 2323: 2320: 2319: 2317: 2315: 2311: 2305: 2302: 2300: 2297: 2295: 2292: 2290: 2287: 2285: 2282: 2280: 2277: 2275: 2272: 2270: 2267: 2265: 2262: 2260: 2257: 2255: 2252: 2250: 2247: 2245: 2242: 2241: 2239: 2237: 2233: 2227: 2224: 2222: 2219: 2217: 2213: 2210: 2209: 2206: 2203: 2201: 2198: 2196: 2193: 2191: 2188: 2186: 2183: 2181: 2178: 2176: 2173: 2171: 2168: 2166: 2163: 2161: 2158: 2157: 2154: 2151: 2149: 2146: 2144: 2141: 2139: 2136: 2134: 2131: 2129: 2126: 2124: 2121: 2119: 2116: 2114: 2111: 2110: 2107: 2104: 2102: 2099: 2097: 2094: 2093: 2091: 2089: 2088:Glucuronosyl- 2085: 2078: 2074: 2071: 2069: 2066: 2064: 2061: 2060: 2058: 2056: 2052: 2046: 2043: 2041: 2038: 2036: 2033: 2031: 2028: 2026: 2023: 2021: 2018: 2014: 2011: 2009: 2006: 2004: 2001: 1999: 1996: 1995: 1994: 1993:Phosphorylase 1991: 1990: 1988: 1986: 1982: 1979: 1977: 1971: 1967: 1962: 1958: 1954: 1947: 1942: 1940: 1935: 1933: 1928: 1927: 1924: 1915: 1911: 1907: 1903: 1899: 1895: 1894:Anal. Biochem 1890: 1886: 1882: 1877: 1872: 1868: 1864: 1863:J. Biol. Chem 1860: 1855: 1851: 1847: 1842: 1837: 1833: 1829: 1825: 1821: 1817: 1812: 1808: 1804: 1800: 1796: 1792: 1788: 1784: 1780: 1774: 1770: 1766: 1762: 1758: 1754: 1750: 1746: 1742: 1741:Exp. Gerontol 1737: 1733: 1729: 1725: 1721: 1717: 1713: 1708: 1704: 1700: 1695: 1690: 1686: 1682: 1681:J. Biol. Chem 1678: 1673: 1669: 1665: 1661: 1657: 1654:(6): 1101–5. 1653: 1649: 1644: 1640: 1636: 1631: 1626: 1622: 1618: 1614: 1610: 1606: 1601: 1597: 1593: 1589: 1585: 1582:(6): 557–64. 1581: 1577: 1571: 1567: 1563: 1559: 1555: 1551: 1547: 1542: 1538: 1534: 1529: 1524: 1519: 1514: 1510: 1506: 1502: 1498: 1494: 1489: 1485: 1481: 1476: 1471: 1467: 1463: 1459: 1454: 1450: 1446: 1441: 1436: 1432: 1428: 1427:J. Biol. Chem 1424: 1419: 1415: 1411: 1406: 1401: 1397: 1393: 1392:J. Biol. Chem 1389: 1384: 1380: 1376: 1372: 1368: 1365:(3): 816–20. 1364: 1360: 1355: 1351: 1347: 1342: 1337: 1333: 1329: 1326:(2): 333–42. 1325: 1321: 1317: 1312: 1308: 1304: 1300: 1296: 1293:(2): 109–15. 1292: 1288: 1283: 1282: 1277: 1268: 1264: 1259: 1254: 1250: 1246: 1245:J. Biol. Chem 1242: 1235: 1232: 1227: 1221: 1219: 1215: 1210: 1206: 1202: 1198: 1194: 1190: 1183: 1180: 1175: 1171: 1165: 1162: 1157: 1153: 1147: 1144: 1140: 1136: 1131: 1129: 1127: 1123: 1119: 1115: 1110: 1108: 1106: 1102: 1095: 1093: 1091: 1090: 1085: 1081: 1077: 1073: 1069: 1065: 1061: 1057: 1056:arthropathies 1053: 1049: 1048:wound healing 1045: 1037: 1035: 1033: 1029: 1025: 1021: 1013: 1011: 1009: 1006: 1002: 998: 996: 983: 978: 974: 970: 967: 963: 956: 954: 951: 947: 943: 939: 936: 932: 928: 921: 919: 913: 909: 906: 900: 898: 894: 888: 884: 881: 877: 870: 868: 862: 858: 855: 849: 847: 843: 837: 833: 830: 828:RefSeq (mRNA) 826: 819: 818: 813: 809: 806: 800: 799: 794: 790: 787: 785: 781: 774: 773: 768: 764: 761: 755: 754: 749: 745: 742: 740: 736: 729: 728: 723: 719: 716: 710: 709: 704: 700: 697: 695: 691: 688: 685: 683: 680: 676: 673: 669: 665: 658: 654: 649: 643: 642:estrous cycle 640: 638: 635: 633: 630: 628: 625: 623: 620: 618: 615: 613: 610: 608: 607:cell adhesion 605: 604: 602: 599: 598: 592: 589: 587: 584: 582: 579: 577: 574: 572: 569: 568: 566: 563: 562: 556: 553: 551: 548: 546: 543: 541: 538: 536: 533: 532: 530: 527: 526: 523: 522:Gene ontology 519: 515: 503: 498: 494: 489: 486: 484: 480: 472: 467: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 394: 390: 386: 382: 378: 374: 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 2899:Translocases 2896: 2883: 2870: 2857: 2844: 2834:Transferases 2831: 2818: 2675:Binding site 2596:transferases 2401:transferases 2215: 1976:transferases 1953:Transferases 1900:(1): 62–70. 1897: 1893: 1866: 1862: 1823: 1819: 1782: 1778: 1747:(6): 641–7. 1744: 1740: 1718:(6): 890–5. 1715: 1711: 1684: 1680: 1651: 1647: 1612: 1608: 1579: 1575: 1552:(2): 165–8. 1549: 1546:Semin. Oncol 1545: 1500: 1496: 1465: 1461: 1430: 1426: 1395: 1391: 1362: 1358: 1323: 1319: 1290: 1286: 1248: 1244: 1234: 1195:(3): 493–7. 1192: 1188: 1182: 1173: 1164: 1155: 1146: 1087: 1041: 1017: 1004: 993: 992: 915: 893:NP_001284365 890: 864: 842:NM_001297436 839: 815: 796: 770: 751: 725: 706: 686: 681: 449:aortic valve 333: 326: 53:External IDs 2670:Active site 2055:Galactosyl- 1052:fibroblasts 421:ankle joint 391:pericardium 375:right ovary 292:18,075,467 279:18,063,585 191:51,723,991 178:51,713,112 31:Identifiers 2942:Categories 2873:Isomerases 2847:Hydrolases 2714:Regulation 2008:Cellobiose 1648:Oncol. Rep 1320:Biochem. J 1141:, May 2017 1120:, May 2017 1096:References 1072:metastasis 1068:leukocytes 997:synthase 1 995:Hyaluronan 383:left ovary 337:(ortholog) 74:HomoloGene 2752:EC number 2399:Pentosyl- 2314:Mannosyl- 1985:Glucosyl- 1826:(1): 89. 1014:Structure 918:NP_032241 897:NP_001514 867:NM_008215 846:NM_001523 672:Orthologs 571:cytoplasm 367:vena cava 82:GeneCards 2953:EC 2.4.1 2776:Kinetics 2700:Cofactor 2663:Activity 2236:Fucosyl- 2003:Glycogen 1974:Hexosyl- 1914:17904513 1885:17611197 1850:17353931 1807:37598580 1799:16786194 1769:54406345 1761:16723203 1732:16564133 1703:16258173 1668:15870928 1639:15731173 1596:14636845 1566:12720129 1537:12477932 1484:12239172 1449:11790779 1307:10093717 1267:17540771 1189:Genomics 1137:– 1116:– 1076:homology 1058:such as 1038:Function 1032:synthase 966:Wikidata 651:Sources: 591:membrane 359:testicle 170:19q13.41 2932:Biology 2886:Ligases 2656:Enzymes 2614:ST8SIA4 2472:Sirtuin 2205:UGT2B28 2200:UGT2B17 2195:UGT2B15 2190:UGT2B11 2185:UGT2B10 2153:UGT1A10 2077:C1GALT1 1841:1847948 1630:1894997 1505:Bibcode 1414:8798544 1379:8651928 1350:3099751 1341:1146992 1209:9169154 1139:Ensembl 1118:Ensembl 784:UniProt 739:Ensembl 678:Species 657:QuickGO 445:trachea 312:pattern 38:Aliases 2918:Portal 2860:Lyases 2594:Sialyl 2590:2.4.99 2410:Ribose 2249:POFUT2 2244:POFUT1 2180:UGT2B7 2175:UGT2B4 2170:UGT2A3 2165:UGT2A2 2160:UGT2A1 2148:UGT1A9 2143:UGT1A8 2138:UGT1A7 2133:UGT1A6 2128:UGT1A5 2123:UGT1A4 2118:UGT1A3 2113:UGT1A1 2106:B3GAT3 2101:B3GAT2 2096:B3GAT1 1998:Starch 1912:  1883:  1848:  1838:  1805:  1797:  1767:  1759:  1730:  1701:  1666:  1637:  1627:  1594:  1564:  1535:  1528:139241 1525:  1482:  1447:  1412:  1377:  1348:  1338:  1305:  1265:  1207:  1044:joints 1001:enzyme 999:is an 952:search 950:PubMed 817:Q61647 798:Q92839 694:Entrez 483:BioGPS 437:embryo 70:106590 62:601463 2812:Types 2562:XYLT2 2557:XYLT1 2545:Other 2530:ECGF1 2514:Other 2395:2.4.2 2381:ALG12 2332:POMT2 2327:POMT1 2304:FUT11 2299:FUT10 1970:2.4.1 1803:S2CID 1765:S2CID 1609:Blood 1462:Blood 727:15116 687:Mouse 682:Human 653:Amigo 425:ankle 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 2904:list 2897:EC7 2891:list 2884:EC6 2878:list 2871:EC5 2865:list 2858:EC4 2852:list 2845:EC3 2839:list 2832:EC2 2826:list 2819:EC1 2376:ALG9 2371:ALG8 2366:ALG6 2361:ALG3 2356:ALG2 2351:ALG1 2344:DPM3 2339:DPM1 2294:FUT9 2289:FUT8 2284:FUT7 2279:FUT6 2274:FUT5 2269:FUT4 2264:FUT3 2259:FUT2 2254:FUT1 2226:HAS3 2221:HAS2 2216:HAS1 2013:Myo- 1963:2.4) 1910:PMID 1881:PMID 1846:PMID 1795:PMID 1757:PMID 1728:PMID 1716:1760 1699:PMID 1664:PMID 1635:PMID 1592:PMID 1562:PMID 1533:PMID 1480:PMID 1445:PMID 1410:PMID 1375:PMID 1346:PMID 1303:PMID 1263:PMID 1205:PMID 1082:, a 1064:CD44 1008:gene 1005:HAS1 708:3036 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 86:HAS1 78:1165 58:OMIM 45:HAS1 22:HAS1 1902:doi 1898:371 1871:doi 1867:282 1836:PMC 1828:doi 1787:doi 1783:292 1749:doi 1720:doi 1689:doi 1685:280 1656:doi 1625:PMC 1617:doi 1613:105 1584:doi 1554:doi 1523:PMC 1513:doi 1470:doi 1466:100 1435:doi 1431:277 1400:doi 1396:271 1367:doi 1363:222 1336:PMC 1328:doi 1324:237 1295:doi 1253:doi 1249:282 1197:doi 288:End 187:End 90:OMA 66:MGI 2944:: 2592:: 2523:: 2397:: 2214:: 1972:: 1961:EC 1955:: 1908:. 1896:. 1879:. 1865:. 1861:. 1844:. 1834:. 1822:. 1818:. 1801:. 1793:. 1781:. 1763:. 1755:. 1745:41 1743:. 1726:. 1714:. 1697:. 1683:. 1679:. 1662:. 1652:13 1650:. 1633:. 1623:. 1611:. 1607:. 1590:. 1580:47 1578:. 1560:. 1550:30 1548:. 1531:. 1521:. 1511:. 1501:99 1499:. 1495:. 1478:. 1464:. 1460:. 1443:. 1429:. 1425:. 1408:. 1394:. 1390:. 1373:. 1361:. 1344:. 1334:. 1322:. 1318:. 1301:. 1291:27 1289:. 1261:. 1247:. 1243:. 1217:^ 1203:. 1193:41 1191:. 1172:. 1154:. 1125:^ 1104:^ 1010:. 655:/ 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 2920:: 2906:) 2902:( 2893:) 2889:( 2880:) 2876:( 2867:) 2863:( 2854:) 2850:( 2841:) 2837:( 2828:) 2824:( 2648:e 2641:t 2634:v 2079:) 2075:( 1959:( 1945:e 1938:t 1931:v 1916:. 1904:: 1887:. 1873:: 1852:. 1830:: 1824:3 1809:. 1789:: 1771:. 1751:: 1734:. 1722:: 1705:. 1691:: 1670:. 1658:: 1641:. 1619:: 1598:. 1586:: 1568:. 1556:: 1539:. 1515:: 1507:: 1486:. 1472:: 1451:. 1437:: 1416:. 1402:: 1381:. 1369:: 1352:. 1330:: 1309:. 1297:: 1269:. 1255:: 1228:. 1211:. 1199:: 1176:. 1158:. 212:) 109:) 92::

Index

Aliases
HAS1
OMIM
601463
MGI
106590
HomoloGene
1165
GeneCards
HAS1
OMA
HAS1 - orthologs
Human
Chromosome 19 (human)
Chr.
Chromosome 19 (human)
Chromosome 19 (human)
Genomic location for HAS1
Genomic location for HAS1
Band
bp
bp
Mouse
Chromosome 17 (mouse)
Chr.
Chromosome 17 (mouse)
Genomic location for HAS1
Genomic location for HAS1
Band
bp

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