301:
278:
175:
200:
559:
552:
307:
206:
1776:
50:
1472:"Generation of minor histocompatibility antigen HA-1-specific cytotoxic T cells restricted by nonself HLA molecules: a potential strategy to treat relapsed leukemia after HLA-mismatched stem cell transplantation"
1301:
van Lochem E, van der Keur M, Mommaas AM, et al. (1997). "Functional expression of minor histocompatibility antigens on human peripheral blood dendritic cells and epidermal
Langerhans cells".
1638:
Kotzampasaki EM, Spyropoulou-Vlachou MS, Kalofoutis C, et al. (2005). "Minor histocompatibility antigen HA-1 and HPA-5 polymorphisms in HLA-identical related bone marrow transplantation".
1369:
Kaminski WE, Piehler A, Schmitz G (2001). "Genomic organization of the human cholesterol-responsive ABC transporter ABCA7: tandem linkage with the minor histocompatibility antigen HA-1 gene".
1243:"Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain"
1340:
Aróstegui JI, Gallardo D, Rodríguez-Luaces M, et al. (2001). "Genomic typing of minor histocompatibility antigen HA-1 by reference strand mediated conformation analysis (RSCA)".
1398:
Gillespie G, Mutis T, Schrama E, et al. (2002). "HLA class I-minor histocompatibility antigen tetramers select cytotoxic T cells with high avidity to the natural ligand".
314:
213:
1566:
Wilke M, Dolstra H, Maas F, et al. (2004). "Quantification of the HA-1 gene product at the RNA level; relevance for immunotherapy of hematological malignancies".
1737:
Krishnan NS, Higgins RM, Lam FT, et al. (2007). "HA-1 mismatch has significant effect in chronic allograft nephropathy in clinical renal transplantation".
787:
768:
136:
1206:
Wilke M, Pool J, den Haan JM, Goulmy E (Jan 1999). "Genomic identification of the minor histocompatibility antigen HA-1 locus by allele-specific PCR".
1845:
1704:"Homozygosity for the 168His variant of the minor histocompatibility antigen HA-1 is associated with reduced risk of primary Sjögren's syndrome"
1821:
1840:
1188:
1170:
300:
1042:
277:
1035:
1282:
1157:
1136:
199:
174:
1153:
47:
1132:
313:
212:
116:
1241:
Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (May 1997).
306:
205:
1814:
832:
124:
1669:"Cord blood comprises antigen-experienced T cells specific for maternal minor histocompatibility antigen HA-1"
813:
1807:
188:
1526:
103:
1014:
1010:
985:
981:
977:
973:
947:
939:
918:
910:
906:
902:
1626:
1501:
1458:
148:
1515:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
1018:
989:
943:
914:
1754:
1725:
1690:
1655:
1618:
1583:
1554:
1493:
1450:
1415:
1386:
1357:
1328:
1264:
1223:
144:
96:
40:
1791:
1746:
1715:
1680:
1647:
1608:
1575:
1544:
1534:
1483:
1440:
1407:
1378:
1349:
1318:
1310:
1254:
1215:
393:
324:
268:
223:
558:
551:
368:
107:, HA-1, HLA-HA1, HMHA1, histocompatibility (minor) HA-1, Rho GTPase activating protein 45
1530:
1750:
1651:
1219:
1549:
1514:
1353:
1314:
702:
697:
692:
687:
682:
666:
661:
656:
651:
646:
641:
636:
631:
626:
610:
605:
600:
1834:
1787:
1445:
1428:
587:
1630:
1505:
1462:
128:
386:
165:
152:
1193:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1175:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1685:
1668:
1488:
1471:
1411:
469:
285:
182:
132:
1259:
1242:
1597:"Complete sequencing and characterization of 21,243 full-length human cDNAs"
1429:"Expression of minor histocompatibility antigen, HA-1, in solid tumor cells"
732:
529:
407:
352:
339:
251:
238:
140:
1758:
1729:
1694:
1659:
1622:
1587:
1579:
1558:
1539:
1497:
1454:
1419:
1390:
1382:
1361:
1720:
1703:
1332:
1268:
1227:
1082:
1077:
1066:
877:
858:
1098:
844:
799:
73:
69:
1323:
1050:
754:
1775:
1667:
Mommaas B, Stegehuis-Kamp JA, van
Halteren AG, et al. (2005).
1613:
1596:
717:
713:
1783:
1105:
567:
120:
1513:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
376:
1795:
693:
regulation of small GTPase mediated signal transduction
1702:
Harangi M, Kaminski WE, Fleck M, et al. (2005).
541:
1283:"Entrez Gene: HMHA1 histocompatibility (minor) HA-1"
1470:Mutis T, Blokland E, Kester M, et al. (2002).
1003:
966:
932:
895:
1595:Ota T, Suzuki Y, Nishikawa T, et al. (2004).
1149:
1147:
1145:
1128:
1126:
1124:
323:
222:
1427:Fujii N, Hiraki A, Ikeda K, et al. (2002).
16:Protein-coding gene in the species Homo sapiens
1154:GRCm38: Ensembl release 89: ENSMUSG00000035697
1815:
8:
1133:GRCh38: Ensembl release 89: ENSG00000180448
1822:
1808:
728:
583:
364:
263:
160:
58:
1719:
1684:
1612:
1548:
1538:
1487:
1444:
1322:
1258:
1120:
683:positive regulation of GTPase activity
18:
1095:Minor histocompatibility protein HA-1
328:
289:
284:
227:
186:
181:
7:
1772:
1770:
1794:. You can help Knowledge (XXG) by
1751:10.1016/j.transproceed.2007.02.066
1652:10.1016/j.transproceed.2004.06.007
1220:10.1111/j.1399-0039.1998.tb03053.x
1000:
963:
929:
892:
868:
849:
823:
804:
778:
759:
546:
464:
402:
381:
14:
1354:10.1034/j.1399-0039.2000.560109.x
1101:that in humans is encoded by the
688:intracellular signal transduction
1774:
1446:10.1097/00007890-200204150-00022
557:
550:
312:
305:
299:
276:
211:
204:
198:
173:
1846:Human chromosome 19 gene stubs
568:More reference expression data
530:More reference expression data
1:
1371:Biochem. Biophys. Res. Commun
1315:10.1016/S0966-3274(96)80009-8
297:
196:
1841:Genes on human chromosome 19
1519:Proc. Natl. Acad. Sci. U.S.A
512:subcutaneous adipose tissue
1862:
1769:
1686:10.1182/blood-2004-07-2832
1489:10.1182/blood-2002-01-0024
1189:"Mouse PubMed Reference:"
1171:"Human PubMed Reference:"
1081:
1076:
1072:
1065:
1049:
1030:
1007:
970:
959:
936:
899:
888:
875:
871:
856:
852:
843:
830:
826:
811:
807:
798:
785:
781:
766:
762:
753:
738:
731:
727:
711:
611:GTPase activator activity
586:
582:
565:
549:
540:
527:
476:
467:
414:
405:
375:
367:
363:
346:
333:
296:
275:
266:
262:
245:
232:
195:
172:
163:
159:
114:
111:
101:
94:
89:
66:
61:
44:
39:
34:
30:
26:
21:
1043:Chr 10: 79.85 – 79.87 Mb
703:neutrophil degranulation
642:azurophil granule lumen
637:secretory granule lumen
1580:10.1038/sj.thj.6200318
1540:10.1073/pnas.242603899
1412:10.1038/sj/thj/6200065
1383:10.1006/bbrc.2000.3880
1260:10.1093/dnares/3.5.321
1036:Chr 19: 1.07 – 1.09 Mb
488:mesenteric lymph nodes
1721:10.1002/eji.200425406
508:stroma of bone marrow
291:Chromosome 10 (mouse)
189:Chromosome 19 (human)
632:extracellular region
153:ARHGAP45 - orthologs
62:List of PDB id codes
35:Available structures
1531:2002PNAS...9916899M
1525:(26): 16899–16903.
698:signal transduction
1782:This article on a
833:ENSMUSG00000035697
676:Biological process
620:Cellular component
594:Molecular function
500:tibiofemoral joint
1803:
1802:
1092:
1091:
1088:
1087:
1061:
1060:
1026:
1025:
997:
996:
955:
954:
926:
925:
884:
883:
865:
864:
839:
838:
820:
819:
794:
793:
775:
774:
723:
722:
606:metal ion binding
578:
577:
574:
573:
536:
535:
523:
522:
461:
460:
454:bone marrow cells
359:
358:
258:
257:
85:
84:
81:
80:
45:Ortholog search:
1853:
1824:
1817:
1810:
1778:
1771:
1762:
1745:(5): 1439–1445.
1739:Transplant. Proc
1733:
1723:
1698:
1688:
1679:(4): 1823–1827.
1663:
1646:(6): 1735–1738.
1640:Transplant. Proc
1634:
1616:
1591:
1562:
1552:
1542:
1509:
1491:
1466:
1448:
1439:(7): 1137–1141.
1423:
1394:
1365:
1336:
1326:
1303:Transpl. Immunol
1287:
1286:
1279:
1273:
1272:
1262:
1238:
1232:
1231:
1203:
1197:
1196:
1185:
1179:
1178:
1167:
1161:
1151:
1140:
1130:
1074:
1073:
1045:
1038:
1021:
1001:
992:
964:
960:RefSeq (protein)
950:
930:
921:
893:
869:
850:
824:
805:
779:
760:
729:
584:
570:
561:
554:
547:
532:
472:
470:Top expressed in
465:
434:secondary oocyte
410:
408:Top expressed in
403:
382:
365:
355:
342:
331:
316:
309:
303:
292:
280:
264:
254:
241:
230:
215:
208:
202:
191:
177:
161:
155:
106:
99:
76:
59:
53:
32:
31:
19:
1861:
1860:
1856:
1855:
1854:
1852:
1851:
1850:
1831:
1830:
1829:
1828:
1767:
1765:
1736:
1708:Eur. J. Immunol
1701:
1666:
1637:
1594:
1565:
1512:
1469:
1433:Transplantation
1426:
1397:
1368:
1342:Tissue Antigens
1339:
1300:
1296:
1294:Further reading
1291:
1290:
1281:
1280:
1276:
1240:
1239:
1235:
1208:Tissue Antigens
1205:
1204:
1200:
1187:
1186:
1182:
1169:
1168:
1164:
1152:
1143:
1131:
1122:
1117:
1111:
1083:View/Edit Mouse
1078:View/Edit Human
1041:
1034:
1031:Location (UCSC)
1017:
1013:
1009:
988:
984:
980:
976:
972:
946:
942:
938:
917:
913:
909:
905:
901:
814:ENSG00000180448
707:
671:
667:cell projection
662:ruffle membrane
652:plasma membrane
615:
601:protein binding
566:
556:
555:
528:
519:
514:
510:
506:
502:
498:
494:
490:
486:
482:
468:
457:
452:
448:
444:
440:
436:
432:
428:
424:
420:
406:
350:
337:
329:
319:
318:
317:
310:
290:
267:Gene location (
249:
236:
228:
218:
217:
216:
209:
187:
164:Gene location (
115:
102:
95:
68:
46:
17:
12:
11:
5:
1859:
1857:
1849:
1848:
1843:
1833:
1832:
1827:
1826:
1819:
1812:
1804:
1801:
1800:
1779:
1764:
1763:
1734:
1714:(1): 305–317.
1699:
1664:
1635:
1614:10.1038/ng1285
1592:
1574:(5): 315–320.
1563:
1510:
1482:(2): 547–552.
1467:
1424:
1395:
1377:(3): 782–789.
1366:
1337:
1309:(2): 151–157.
1297:
1295:
1292:
1289:
1288:
1274:
1253:(5): 321–329.
1233:
1214:(4): 312–317.
1198:
1180:
1162:
1141:
1119:
1118:
1116:
1113:
1090:
1089:
1086:
1085:
1080:
1070:
1069:
1063:
1062:
1059:
1058:
1056:
1054:
1047:
1046:
1039:
1032:
1028:
1027:
1024:
1023:
1005:
1004:
998:
995:
994:
968:
967:
961:
957:
956:
953:
952:
934:
933:
927:
924:
923:
897:
896:
890:
886:
885:
882:
881:
873:
872:
866:
863:
862:
854:
853:
847:
841:
840:
837:
836:
828:
827:
821:
818:
817:
809:
808:
802:
796:
795:
792:
791:
783:
782:
776:
773:
772:
764:
763:
757:
751:
750:
745:
740:
736:
735:
725:
724:
721:
720:
709:
708:
706:
705:
700:
695:
690:
685:
679:
677:
673:
672:
670:
669:
664:
659:
654:
649:
644:
639:
634:
629:
623:
621:
617:
616:
614:
613:
608:
603:
597:
595:
591:
590:
580:
579:
576:
575:
572:
571:
563:
562:
544:
538:
537:
534:
533:
525:
524:
521:
520:
518:
517:
513:
509:
505:
501:
497:
493:
489:
485:
481:
477:
474:
473:
462:
459:
458:
456:
455:
451:
447:
443:
439:
435:
431:
427:
423:
419:
415:
412:
411:
399:
398:
390:
379:
373:
372:
369:RNA expression
361:
360:
357:
356:
348:
344:
343:
335:
332:
327:
321:
320:
311:
304:
298:
294:
293:
288:
282:
281:
273:
272:
260:
259:
256:
255:
247:
243:
242:
234:
231:
226:
220:
219:
210:
203:
197:
193:
192:
185:
179:
178:
170:
169:
157:
156:
113:
109:
108:
100:
92:
91:
87:
86:
83:
82:
79:
78:
64:
63:
55:
54:
43:
37:
36:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1858:
1847:
1844:
1842:
1839:
1838:
1836:
1825:
1820:
1818:
1813:
1811:
1806:
1805:
1799:
1797:
1793:
1789:
1788:chromosome 19
1785:
1780:
1777:
1773:
1768:
1760:
1756:
1752:
1748:
1744:
1740:
1735:
1731:
1727:
1722:
1717:
1713:
1709:
1705:
1700:
1696:
1692:
1687:
1682:
1678:
1674:
1670:
1665:
1661:
1657:
1653:
1649:
1645:
1641:
1636:
1632:
1628:
1624:
1620:
1615:
1610:
1606:
1602:
1598:
1593:
1589:
1585:
1581:
1577:
1573:
1569:
1564:
1560:
1556:
1551:
1546:
1541:
1536:
1532:
1528:
1524:
1520:
1516:
1511:
1507:
1503:
1499:
1495:
1490:
1485:
1481:
1477:
1473:
1468:
1464:
1460:
1456:
1452:
1447:
1442:
1438:
1434:
1430:
1425:
1421:
1417:
1413:
1409:
1406:(6): 403–10.
1405:
1401:
1396:
1392:
1388:
1384:
1380:
1376:
1372:
1367:
1363:
1359:
1355:
1351:
1347:
1343:
1338:
1334:
1330:
1325:
1320:
1316:
1312:
1308:
1304:
1299:
1298:
1293:
1284:
1278:
1275:
1270:
1266:
1261:
1256:
1252:
1248:
1244:
1237:
1234:
1229:
1225:
1221:
1217:
1213:
1209:
1202:
1199:
1194:
1190:
1184:
1181:
1176:
1172:
1166:
1163:
1159:
1155:
1150:
1148:
1146:
1142:
1138:
1134:
1129:
1127:
1125:
1121:
1114:
1112:
1109:
1107:
1104:
1100:
1096:
1084:
1079:
1075:
1071:
1068:
1064:
1057:
1055:
1052:
1048:
1044:
1040:
1037:
1033:
1029:
1022:
1020:
1016:
1012:
1006:
1002:
999:
993:
991:
987:
983:
979:
975:
969:
965:
962:
958:
951:
949:
945:
941:
935:
931:
928:
922:
920:
916:
912:
908:
904:
898:
894:
891:
889:RefSeq (mRNA)
887:
880:
879:
874:
870:
867:
861:
860:
855:
851:
848:
846:
842:
835:
834:
829:
825:
822:
816:
815:
810:
806:
803:
801:
797:
790:
789:
784:
780:
777:
771:
770:
765:
761:
758:
756:
752:
749:
746:
744:
741:
737:
734:
730:
726:
719:
715:
710:
704:
701:
699:
696:
694:
691:
689:
686:
684:
681:
680:
678:
675:
674:
668:
665:
663:
660:
658:
655:
653:
650:
648:
645:
643:
640:
638:
635:
633:
630:
628:
625:
624:
622:
619:
618:
612:
609:
607:
604:
602:
599:
598:
596:
593:
592:
589:
588:Gene ontology
585:
581:
569:
564:
560:
553:
548:
545:
543:
539:
531:
526:
515:
511:
507:
503:
499:
495:
491:
487:
483:
479:
478:
475:
471:
466:
463:
453:
449:
445:
441:
437:
433:
429:
425:
421:
417:
416:
413:
409:
404:
401:
400:
397:
395:
391:
389:
388:
384:
383:
380:
378:
374:
370:
366:
362:
354:
349:
345:
341:
336:
330:10|10 C1
326:
322:
315:
308:
302:
295:
287:
283:
279:
274:
270:
265:
261:
253:
248:
244:
240:
235:
225:
221:
214:
207:
201:
194:
190:
184:
180:
176:
171:
167:
162:
158:
154:
150:
146:
142:
138:
134:
130:
126:
122:
118:
110:
105:
98:
93:
88:
77:
75:
71:
65:
60:
57:
56:
52:
49:
42:
38:
33:
29:
25:
20:
1796:expanding it
1781:
1766:
1742:
1738:
1711:
1707:
1676:
1672:
1643:
1639:
1607:(1): 40–45.
1604:
1600:
1571:
1567:
1522:
1518:
1479:
1475:
1436:
1432:
1403:
1399:
1374:
1370:
1348:(1): 69–76.
1345:
1341:
1306:
1302:
1277:
1250:
1246:
1236:
1211:
1207:
1201:
1192:
1183:
1174:
1165:
1110:
1102:
1094:
1093:
1015:NP_001334003
1011:NP_001136173
1008:
986:NP_001308161
982:NP_001269264
978:NP_001269263
974:NP_001245257
971:
948:NM_001347074
940:NM_001142701
937:
919:NM_001321232
911:NM_001282335
907:NM_001282334
903:NM_001258328
900:
876:
857:
831:
812:
786:
767:
747:
742:
392:
385:
112:External IDs
67:
516:ankle joint
504:bone marrow
480:granulocyte
418:granulocyte
351:79,867,306
338:79,852,487
90:Identifiers
1835:Categories
1601:Nat. Genet
1568:Hematol. J
1400:Hematol. J
1160:, May 2017
1139:, May 2017
1115:References
442:lymph node
396:(ortholog)
250:1,086,628
237:1,065,923
133:HomoloGene
1786:on human
1324:1887/2991
1019:NP_081797
990:NP_036424
944:NM_027521
915:NM_012292
733:Orthologs
647:cytoplasm
141:GeneCards
1759:17580157
1730:15593299
1695:15498856
1660:15350465
1631:21903526
1623:14702039
1588:14502255
1559:12477932
1506:31440495
1498:12091347
1463:21504762
1455:11965046
1420:11920221
1391:11095984
1362:10958358
1156:–
1135:–
1067:Wikidata
712:Sources:
657:membrane
450:appendix
438:monocyte
145:ARHGAP45
104:ARHGAP45
22:ARHGAP45
1527:Bibcode
1333:8843592
1269:9039502
1247:DNA Res
1228:9820596
1158:Ensembl
1137:Ensembl
1099:protein
845:UniProt
800:Ensembl
739:Species
718:QuickGO
627:cytosol
371:pattern
229:19p13.3
129:1917969
97:Aliases
1757:
1728:
1693:
1658:
1629:
1621:
1586:
1557:
1550:139241
1547:
1504:
1496:
1461:
1453:
1418:
1389:
1360:
1331:
1267:
1226:
1053:search
1051:PubMed
878:Q3TBD2
859:Q92619
755:Entrez
542:BioGPS
496:spleen
484:thymus
446:thymus
430:oocyte
426:spleen
121:601155
1790:is a
1673:Blood
1627:S2CID
1502:S2CID
1476:Blood
1459:S2CID
1103:HMHA1
1097:is a
788:70719
769:23526
748:Mouse
743:Human
714:Amigo
492:blood
422:blood
394:Mouse
387:Human
334:Start
269:Mouse
233:Start
166:Human
137:69120
1792:stub
1784:gene
1755:PMID
1726:PMID
1691:PMID
1656:PMID
1619:PMID
1584:PMID
1555:PMID
1494:PMID
1451:PMID
1416:PMID
1387:PMID
1358:PMID
1329:PMID
1265:PMID
1224:PMID
1106:gene
377:Bgee
325:Band
286:Chr.
224:Band
183:Chr.
117:OMIM
74:3FT3
70:3D25
51:RCSB
48:PDBe
1747:doi
1716:doi
1681:doi
1677:105
1648:doi
1609:doi
1576:doi
1545:PMC
1535:doi
1484:doi
1480:100
1441:doi
1408:doi
1379:doi
1375:278
1350:doi
1319:hdl
1311:doi
1255:doi
1216:doi
347:End
246:End
149:OMA
125:MGI
41:PDB
1837::
1753:.
1743:39
1741:.
1724:.
1712:35
1710:.
1706:.
1689:.
1675:.
1671:.
1654:.
1644:36
1642:.
1625:.
1617:.
1605:36
1603:.
1599:.
1582:.
1570:.
1553:.
1543:.
1533:.
1523:99
1521:.
1517:.
1500:.
1492:.
1478:.
1474:.
1457:.
1449:.
1437:73
1435:.
1431:.
1414:.
1402:.
1385:.
1373:.
1356:.
1346:56
1344:.
1327:.
1317:.
1305:.
1263:.
1249:.
1245:.
1222:.
1212:52
1210:.
1191:.
1173:.
1144:^
1123:^
1108:.
716:/
353:bp
340:bp
252:bp
239:bp
147:;
143::
139:;
135::
131:;
127::
123:;
119::
72:,
1823:e
1816:t
1809:v
1798:.
1761:.
1749::
1732:.
1718::
1697:.
1683::
1662:.
1650::
1633:.
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1590:.
1578::
1572:4
1561:.
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1404:1
1393:.
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1335:.
1321::
1313::
1307:4
1285:.
1271:.
1257::
1251:3
1230:.
1218::
1195:.
1177:.
271:)
168:)
151::
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