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Haplogroup K2

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Louzada, Sandra; Desalle, Rob; Ritchie, Graham R S; Cerveira, Eliza; Fitzgerald, Tomas W; Garrison, Erik; Marcketta, Anthony; Mittelman, David; Romanovitch, Mallory; Zhang, Chengsheng; Zheng-Bradley, Xiangqun; Abecasis, Gonçalo R; McCarroll, Steven A; Flicek, Paul; Underhill, Peter A; Coin, Lachlan; Zerbino, Daniel R; Yang, Fengtang; Lee, Charles; Clarke, Laura; Auton, Adam; Erlich, Yaniv; Handsaker, Robert E; Bustamante, Carlos D; Tyler-Smith, Chris (June 2016).
1283: 1175:"This pattern leads us to hypothesize a southeastern Asian origin for P-P295 and a later expansion of the ancestor of subhaplogroups R and Q into mainland Asia. An alternative explanation would involve an extinction event of ancestral P-P295* chromosomes everywhere in Asia. These scenarios are equally parsimonious. They involve either a migration event (P* chromosomes from Indonesia to mainland Asia) or an extinction event of P-P295* paragroup in Eurasia." 366:". According to Karafet et al., the estimated dates for the branching of K, K2, K2b and P point to a "rapid diversification" within K2 "that likely occurred in Southeast Asia", with subsequent "westward expansions" of P*, P1, Q and R. However, these authors also stipulated that haplogroup K might have arisen in Eurasia and later went extinct there, and that either origin hypothesis is "equally parsimonious". 1203:
Nagle, Nano; Ballantyne, Kaye N.; van Oven, Mannis; Tyler-Smith, Chris; Xue, Yali; Taylor, Duncan; Wilcox, Stephen; Wilcox, Leah; Turkalov, Rust; van Oorschot, Roland A.H.; McAllister, Peter; Williams, Lesley; Kayser, Manfred; Mitchell, Robert J.; Genographic, Consortium. (March 2016). "Antiquity and
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Fu, Qiaomei; Li, Heng; Moorjani, Priya; Jay, Flora; Slepchenko, Sergey M.; Bondarev, Aleksei A.; Johnson, Philip L. F.; Aximu-Petri, Ayinuer; Prüfer, Kay; de Filippo, Cesare; Meyer, Matthias; Zwyns, Nicolas; Salazar-García, Domingo C.; Kuzmin, Yaroslav V.; Keates, Susan G.; Kosintsev, Pavel A.;
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Poznik, G David; Xue, Yali; Mendez, Fernando L; Willems, Thomas F; Massaia, Andrea; Wilson Sayres, Melissa A; Ayub, Qasim; McCarthy, Shane A; Narechania, Apurva; Kashin, Seva; Chen, Yuan; Banerjee, Ruby; Rodriguez-Flores, Juan L; Cerezo, Maria; Shao, Haojing; Gymrek, Melissa; Malhotra, Ankit;
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K-M2313*, which as yet has no phylogenetic name, has been documented in two living individuals, who have ethnic ties to India and South East Asia. In addition, K-Y28299, which appears to be a primary branch of K-M2313, has been found in three living individuals from India. See: Poznik
717:; the haplogroups subordinate to MNOPS would likely have been renamed "U", "V", "W" and "X", and MNOPS would therefore have become "MNOPSUVWX". This posed a problem, because there was no way to disambiguate between "K(xLT)" in the broad and narrow meanings of the term. 962:
Bergström, Anders; Nagle, Nano; Chen, Yuan; McCarthy, Shane; Pollard, Martin O.; Ayub, Qasim; Wilcox, Stephen; Wilcox, Leah; van Oorschot, Roland A.H.; McAllister, Peter; Williams, Lesley; Xue, Yali; Mitchell, R. John; Tyler-Smith, Chris (21 March 2016).
679:, was provisionally named "pre-NO" (among other names), as it was believed initially to be ancestral to K2a (NO). However, it was later found to be a primary branch of Haplogroup K2 (K-M526) and a sibling of K2a; the new clade was renamed K2e. 735:
Razhev, Dmitry I.; Richards, Michael P.; Peristov, Nikolai V.; Lachmann, Michael; Douka, Katerina; Higham, Thomas F. G.; Slatkin, Montgomery; Hublin, Jean-Jacques; Reich, David; Kelso, Janet; Viola, T. Bence; Pääbo, Svante (October 2014).
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A rapid diversification within and from K2 (M526), most likely in Southeast Asia, is suggested by estimates of the point in time that K2 branched off from K* (M9). Likewise the branching from K2 of K2b (P331) and
1778: 327:. It is likely that haplogroup P diverged somewhere in South Asia into P1, which expanded into Siberia and Northern Eurasia, and into P2, which expanded into Oceania and Southeast Asia. 713:
in 2012 to replace MNOPS, was controversial. Under the previous methodology, a term such as "K(xLT)" designated all clades and subclades that belonged to K, but did not belong to
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K2c, K2d, and K2e are extremely rare subhaplogroups that are found in specific parts of South and Southeast Asia. K2c (P261) has been reported only among males in
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Van Oven M, Van Geystelen A, Kayser M, Decorte R, Larmuseau HD (2014). "Seeing the wood for the trees: a minimal reference phylogeny for the human Y chromosome".
289:. Another subclade, NO (M214)* – which for a time was thought to be synonymous with K2a (M2308)* – has not been identified in living individuals or remains. 664:(K2b2 P295) from K2b, as well as Haplogroups Q and R from P (K2b2), and their subsequent expansions westward in Europe, and eastward into the Americas. 1163:"Given the widespread distribution of K, it probably arose somewhere in the Middle East or Central Asia, perhaps in the region of Iran or Pakistan." 588:
At the level of highly derived subclades, K2 is almost universal in some modern Eurasian, Australasian and Native American populations. Haplogroup
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Population geneticist Tatiana Karafet and other researchers (2014) point out that both K2b1 and P* are virtually restricted geographically to
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from Singapore. In addition, K-Y28299, which appears to be a primary branch of K-M2313, has been found in three living individuals from
645: 1267: 2002: 1257: 375: 154: 269:". The only primary branch of K2a, known as K-M2313*, has been documented in two living individuals, who have ethnic ties to 1123: 686:
males carry K-M526*, which could not be classified into a known subclade at the time, and another 27% probably have
209:, while they are less common overall, are also very widespread, in northern Eurasia and the Americas respectively. 1924:
Haplogroup K2b1 (P397/P399) is also known as Haplogroup MS, but has a broader and more complex internal structure.
807:"Improved phylogenetic resolution and rapid diversification of Y-chromosome haplogroup K-M526 in Southeast Asia" 1446: 1116:"Downloadable genotypes of present-day and ancient DNA data (compiled from published papers) | David Reich Lab" 805:
Karafet, Tatiana M; Mendez, Fernando L; Sudoyo, Herawati; Lansing, J Stephen; Hammer, Michael F (March 2015).
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Haplogroup S, as of 2017, is also known as K2b1a. (Previously the name Haplogroup S was assigned to K2b1a4.)
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Haplogroup M, as of 2017, is also known as K2b1b. (Previously the name Haplogroup M was assigned to K2b1d.)
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Basal paragroup K2b* has not been identified among living males but was found in Upper Paleolithic
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paragroup K2* has been identified among native Australians, about 27% of them carry basal K-M526∗.
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This article is about the Y-chromosome haplogroup K2. For mitochondrial DNA haplogroup K2, see
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F-Y27277, sometimes known as F2'4, is both the parent clade of F2 and F4 and a child of F-M89.
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Hallast, Pille; Agdzhoyan, Anastasia; Balanovsky, Oleg; Xue, Yali; Tyler-Smith, Chris (2021).
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is extremely complex, and subclades of it are carried by males native to regions including
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Please help update this article to reflect recent events or newly available information.
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diversity of aboriginal Australian Y-chromosomes: Aboriginal Australian Y-Chromosomes".
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The name K2 was introduced in 2014, following dissatisfaction with the previous names.
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in East and Southeast Asia (as well as recent immigrants to other continents).
980: 653: 363: 339: 270: 170: 1955: 1092: 193:. Many of its branches are very common, the most numerically important being 929: 601: 392: 222: 174: 1826: 1225: 1059: 998: 948: 889: 840: 778: 856:"A Southeast Asian origin for present-day non-African human y chromosomes" 822: 355: 182: 1862:
Haplogroup A0-T is also known as A-L1085 (and previously as A0'1'2'3'4).
905:"Y chromosome diversity, human expansion, drift, and cultural evolution" 903:
Chiaroni, Jacques; Underhill, Peter A.; Cavalli-Sforza, Luca L. (2009).
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was known as "Haplogroup K2". That name has since been re-assigned to
1085: 1959:, 2017, "Details of the Y-SNP markers included in the minimal Y tree" 1096:, 2017, "Details of the Y-SNP markers included in the minimal Y tree" 649: 351: 266: 228:
Rare subclades outside of these major lineages are known mainly from
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Haplogroup K2b (M1221/P331/PF5911) is also known as Haplogroup MPS.
319:, haplogroup K, from which haplogroup P descend, originated in the 1148:
Deep Ancestry: The Landmark DNA Quest to Decipher Our Distant Past
286: 690:(P60, P304, P308; also known as "S-P308") and perhaps 2.0% have 672: 668: 1239: 1276: 675:. K2e (M147), which has been found in two modern cases from 608:-speaking populations. Similarly, the direct descendants of 682:
Studies published in 2014 and 2015 found that up to 27% of
527:) M1221/P331/PF5911, CTS2019/M1205, PF5990/L405, PF5969 – 1848:
International Society of Genetic Genealogy (ISOGG; 2015),
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F549/S22380/M2335/V4208; M2335/Z4952/M2339/E482; CTS11667
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Human Y chromosome DNA grouping indicating common ancestry
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Haplogroup LT (L298/P326) is also known as Haplogroup K1.
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primary subclade of K2a; no phylogenetic name as of 2017
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primary subclade of K2a; no phylogenetic name as of 2017
34:. For the Y-DNA haplogroup known until 2008 as K2, see 461:
M214/Page39; F176/M2314; CTS5858/M2325/F346; CTS11572
38:. For the haplogroup sometimes known as "K-P256", see 965:"Deep Roots for Aboriginal Australian Y Chromosomes" 481:) M175/P186/P191/P196; F369/M1755; F380/M1757/S27659 1318: 121: 94: 84: 74: 63: 49: 529:subclades of K2b include the major haplogroups 1961:(Access date of these pages: 9 December 2017) 1251: 800: 798: 796: 794: 792: 790: 788: 350:now make up "the most frequent haplogroup in 8: 632:. These are now numerically in dominant in: 405:) M526 – formerly known as K(xLT) and MNOPS 384:, K2 is a sibling of basal/paragroup K* and 1933:Haplogroup P (P295) is also klnown as K2b2. 1103:, 2016, DNA Marker Index Chromosome Y V4208 1258: 1244: 1236: 55: 1206:American Journal of Physical Anthropology 1151:. National Geographic Books. p. 79. 1049: 988: 938: 928: 879: 830: 768: 418:found only in ancient remains; see above) 1871:Haplogroup A1 is also known as A1'2'3'4. 1186:"ISOGG 2018 Y-DNA Haplogroup Tree Trunk" 1018: 1016: 1014: 1012: 1010: 1008: 510:found in two living individuals in India 1797: 726: 694:– also known as M-M4 (or "M-M186") and 497:found in one living individual in India 1081: 1079: 1077: 1075: 1073: 1071: 1069: 471:) M231; CTS2947/M2175; Z4891; CTS10118 225:, where they occur at high frequency. 46: 7: 1784:Y-DNA haplogroups of historic people 1759: 1754: 1745: 1743: 1738: 1736: 1731: 1726: 1721: 1715: 1708: 1698: 1696: 1686: 1678: 1666: 1664: 1655: 1647: 1605: 1598: 1592: 1590: 1584: 1578: 1576: 1570: 1564: 1552:       1542: 1536: 1530: 1521: 1516: 1507: 1502: 1493: 1488: 1452: 1438: 1321: 338:. Whereas, in a striking contrast, 312:are the only primary clades of K2b. 1426: 1366: 1349: 1145:Wells, Spencer (20 November 2007). 709:K(xLT), the name introduced by the 811:European Journal of Human Genetics 508:) Y28301/Y28328; Y28358; Y28410 – 495:) Y28299/Y28355; Y28357; Y28412 – 342:(P-M45) and its primary subclades 217:are almost entirely restricted to 25: 1853:. (Access date: 1 February 2015.) 1281: 395:of haplogroup K2 is as follows: 300:(P397/P399) known previously as 1906:, the sibling of Haplogroup LT. 376:Structure of Y-DNA Haplogroup K 612:include the major haplogroups 1: 197:in Europe and South Asia and 1268:Y-chromosome DNA haplogroups 596:, includes most males among 249:K2a* has been found only in 1266:Phylogenetic tree of human 2019: 1850:Y-DNA Haplogroup Tree 2015 1752: 1719: 1676: 1645: 1636: 1628: 1621: 1614: 1607: 1562: 1528: 1514: 1500: 1486: 1470: 1454: 1323: 872:10.1007/s00439-020-02204-9 373: 29: 1773: 1551: 1544: 1478: 1461: 1445: 1440: 1433: 1428: 1419: 1414: 1412: 1405: 1400: 1398: 1391: 1384: 1382: 1375: 1368: 1358: 1351: 1341: 1334: 1332: 1316: 1290:This article needs to be 1274: 981:10.1016/j.cub.2016.01.028 261:, known respectively as " 153:Relative to its age, the 54: 315:According to geneticist 308:(P-P295), also known as 155:internal structure of K2 75:Possible place of origin 2003:Human Y-DNA haplogroups 1898:Between 2002 and 2008, 930:10.1073/pnas.0910803106 711:Y Chromosome Consortium 671:and K2d (P402) only in 380:A direct descendant of 64:Possible time of origin 138:and formerly known as 1120:reich.hms.harvard.edu 823:10.1038/ejhg.2014.106 684:Aboriginal Australian 592:, as a descendant of 253:remains from western 230:Island Southeast Asia 1091:(9 December 2017); 388:(also known as K1). 67:47,000-50,000 years 36:Haplogroup T (Y-DNA) 32:Haplogroup K (mtDNA) 1779:Y-DNA by population 1694:    1173:Karafet et al. 2015 1101:GeneticHomeland.com 1098:(9 December 2017); 921:2009PNAS..10620174C 761:10.1038/nature13810 753:2014Natur.514..445F 1819:10.1002/humu.22468 1545:    1326:Y-chromosomal Adam 1218:10.1002/ajpa.22886 1126:on 2 November 2019 1105:(9 December 2017). 281:from India and an 122:Defining mutations 1990: 1989: 1952:, 2017, "K-M2335" 1950:YFull YTree v5.08 1900:Haplogroup T-M184 1768: 1767: 1713: 1703: 1693: 1684: 1672: 1661: 1653: 1641: 1633: 1626: 1619: 1612: 1557: 1476: 1468: 1459: 1389: 1373: 1356: 1339: 1311: 1310: 1158:978-1-4262-0211-7 1089:, 2017, "K-M2335" 1087:YFull YTree v5.08 747:(7523): 445–449. 251:Upper Paleolithic 129: 128: 40:Haplogroup M-P256 18:Haplogroup K-M526 16:(Redirected from 2010: 1980: 1977: 1971: 1968: 1962: 1940: 1934: 1931: 1925: 1922: 1916: 1913: 1907: 1896: 1890: 1887: 1881: 1878: 1872: 1869: 1863: 1860: 1854: 1845: 1839: 1838: 1802: 1709: 1699: 1687: 1679: 1667: 1657: 1648: 1637: 1629: 1622: 1615: 1608: 1553: 1472: 1463: 1455: 1385: 1369: 1352: 1335: 1319: 1306: 1303: 1297: 1285: 1284: 1277: 1260: 1253: 1246: 1237: 1230: 1229: 1200: 1194: 1193: 1182: 1176: 1170: 1164: 1162: 1142: 1136: 1135: 1133: 1131: 1122:. 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256: 252: 247: 245: 241: 239: 235: 231: 226: 224: 220: 216: 212: 208: 204: 203:Haplogroups N 200: 196: 192: 188: 184: 180: 176: 172: 168: 164: 160: 156: 151: 149: 146:, is a human 145: 141: 137: 133: 132:Haplogroup K2 124: 120: 116: 112: 108: 104: 100: 97: 93: 90: 87: 83: 80: 77: 73: 70: 66: 62: 58: 53: 50:Haplogroup K2 48: 45: 41: 37: 33: 19: 1975: 1966: 1956: 1949: 1944: 1938: 1929: 1920: 1911: 1903: 1894: 1885: 1876: 1867: 1858: 1849: 1843: 1810: 1806: 1800: 1791: 1656:   1599:   1554: 1299: 1291: 1209: 1205: 1198: 1189: 1180: 1168: 1147: 1140: 1130:11 September 1128:. Retrieved 1124:the original 1119: 1110: 1100: 1093: 1086: 1033: 1029: 972: 968: 957: 912: 908: 898: 863: 859: 849: 814: 810: 744: 740: 729: 708: 705: 695: 681: 666: 662:Haplogroup P 658: 638:Central Asia 587: 584:Distribution 576: 566: 556: 528: 524: 518: 509: 505: 501: 496: 492: 488: 478: 474: 468: 464: 458: 454: 448: 442: 438: 432: 426: 422: 417: 413: 409: 402: 398: 397: 390: 382:Haplogroup K 379: 360:Central Asia 329: 325:Central Asia 314: 309: 306:Haplogroup P 301: 296:from China. 294:Tianyuan man 291: 283:ethnic Malay 248: 242: 227: 221:and eastern 179:Central Asia 152: 143: 139: 135: 131: 130: 44: 677:South India 606:Finno-Ugric 416:) M2308 – 321:Middle East 238:Philippines 159:Australasia 95:Descendants 654:South Asia 602:East Asian 364:South Asia 271:South Asia 189:, and the 171:South Asia 1957:PhyloTree 1792:Footnotes 1094:PhyloTree 721:Footnotes 393:phylogeny 370:Structure 223:Indonesia 175:East Asia 101:(M2308); 1997:Category 1954:, and; 1945:op. cit. 1835:23291764 1827:24166809 1465:F-Y27277 1226:26515539 1060:27111036 999:26923783 949:19920170 890:32666166 841:24896152 779:25341783 644:, among 502:K-Y28301 489:K-Y28299 450:NO1-M214 429:) M2313 356:Americas 257:and the 236:and the 183:Americas 85:Ancestor 1669:K-M2313 1662:  1603:  1588:  1574:  1558:  1549:  1540:  1362:  1345:  1292:updated 1051:4884158 990:4819516 940:2787129 917:Bibcode 881:7864842 832:4326703 770:4753769 749:Bibcode 642:Siberia 634:Oceania 459:NO-F176 443:K-M2335 434:NO-F549 423:K-M2313 410:K-M2308 336:Oceania 265:" and " 259:Balkans 255:Siberia 219:Oceania 163:Oceania 105:(MPS); 1904:K-M526 1833:  1825:  1692:  1688:  1683:  1671:  1652:  1479:  1471:  1467:  1462:  1224:  1155:  1058:  1048:  997:  987:  947:  937:  888:  878:  839:  829:  777:  767:  741:Nature 702:Naming 696:K2b1d1 688:K2b1a1 652:, and 650:Europe 628:, and 604:, and 579:) M147 573:K-M147 569:) P402 563:K-P402 559:) P261 553:K-P261 545:, and 520:K-P331 475:O-M175 465:N-M231 399:K-M526 358:, and 354:, the 352:Europe 304:, and 279:Telugu 267:Oase-1 187:Europe 181:, the 140:K(xLT) 136:K-M526 1831:S2CID 1481:GHIJK 457:) or 441:) or 287:India 244:Basal 144:MNOPS 1823:PMID 1650:K2b1 1495:HIJK 1387:A1b1 1343:A0-T 1222:PMID 1153:ISBN 1132:2019 1056:PMID 995:PMID 945:PMID 909:PNAS 886:PMID 837:PMID 775:PMID 673:Java 669:Bali 455:NO1* 427:K2a1 362:and 346:and 334:and 310:K2b2 298:K2b1 273:and 213:and 205:and 142:and 1815:doi 1733:P1a 1728:P1b 1723:P1c 1711:NO1 1639:K2a 1631:K2b 1624:K2c 1617:K2d 1610:K2e 1504:IJK 1377:A1b 1371:A1a 1337:A00 1214:doi 1210:159 1046:PMC 1038:doi 985:PMC 977:doi 935:PMC 925:doi 913:106 876:PMC 868:doi 864:140 827:PMC 819:doi 765:PMC 757:doi 745:514 610:K2b 577:K2e 567:K2d 557:K2c 525:K2b 439:NO* 414:K2a 323:or 240:). 115:K2e 111:K2d 107:K2c 103:K2b 99:K2a 1999:: 1947:; 1829:. 1821:. 1811:35 1809:. 1701:P1 1586:J2 1580:J1 1572:I2 1566:I1 1555:K2 1547:LT 1518:IJ 1474:F3 1457:F1 1421:CF 1416:DE 1407:CT 1393:BT 1360:A1 1354:A0 1328:" 1220:. 1208:. 1188:. 1118:. 1068:^ 1054:. 1044:. 1034:48 1032:. 1028:. 1007:^ 993:. 983:. 973:26 971:. 967:. 943:. 933:. 923:. 911:. 907:. 884:. 874:. 862:. 858:. 835:. 825:. 815:23 813:. 809:. 787:^ 773:. 763:. 755:. 743:. 739:. 698:. 656:. 640:, 636:, 624:, 620:, 616:; 600:, 541:, 537:, 533:; 479:O* 469:N* 403:K2 340:P1 185:, 177:, 173:, 169:, 165:, 161:, 150:. 113:; 109:; 69:BP 1837:. 1817:: 1761:Q 1756:R 1747:O 1740:N 1690:M 1681:S 1659:P 1601:T 1594:L 1538:J 1532:I 1523:K 1509:H 1490:G 1447:F 1442:C 1435:E 1430:D 1402:B 1324:" 1304:) 1300:( 1294:. 1259:e 1252:t 1245:v 1228:. 1216:: 1192:. 1161:. 1134:. 1062:. 1040:: 1001:. 979:: 951:. 927:: 919:: 892:. 870:: 843:. 821:: 781:. 759:: 751:: 630:R 626:Q 622:P 618:S 614:M 575:( 565:( 555:( 547:R 543:Q 539:P 535:S 531:M 523:( 504:( 491:( 477:( 467:( 453:( 437:( 425:( 412:( 401:( 348:R 344:Q 215:S 211:M 207:Q 199:O 195:R 117:. 89:K 42:. 20:)

Index

Haplogroup K-M526
Haplogroup K (mtDNA)
Haplogroup T (Y-DNA)
Haplogroup M-P256

BP
Southeast Asia
K
K2a
K2b
K2c
K2d
K2e
Y-DNA haplogroup
internal structure of K2
Australasia
Oceania
Southeast Asia
South Asia
East Asia
Central Asia
Americas
Europe
Horn of Africa
R
O
Haplogroups N
Q
M
S

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