542:, the Stadie Award from the American Diabetes Association, and the 2010 Mentoring Award from the American Society of Hematology. In 2016 he received the American Society for Cell Biology Women In Cell Biology Sandra K. Masur Senior Leadership Award and was named a Lifetime Fellow by the Society. He received the 2016 Pioneer Award from the Diamond Blackfan Anemia Foundation, and the Metcalf Lifetime Achievement Award from the International Society for Experimental Hematology in 2020. In 2021 he received the Wallace H. Coulter Award for Lifetime Achievement in Hematology from the American Society of Hematology.
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401:, Inc, and Rubius Therapeutics. Together with two parents of children with Dravet Syndrome, he founded Tevard, a company developing novel gene therapy therapeutics for Dravet Syndrome and several other genetic brain disorders. And with two former students he founded Carmine, which develops red cell extracellular vesicles as gene delivery vehicles.
556:(Physiology or Medicine, 2013). Eight of his students and fellows are elected Members of the U.S. National Academies of Science or Medicine. In 1982 Dr. Lodish was elected to the Cleveland Heights High School (Cleveland Heights, Ohio) Alumni Hall of Fame, an honor he shares with his two younger brothers Leonard and Richard.
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He has taught undergraduate courses at MIT in
Molecular Biology, Cell Biology, and most recently Molecular Biotechnology. Together with Professor Andrew Lo of the MIT Sloan School of Management and several colleagues in the Biology and Biological Engineering Departments, he is currently teaching the
376:, where he also was Chair of the Research Committee of the Board of Trustees. From 2007 to 2014 he was Chair of the Scientific Advisory Board of the Massachusetts Life Sciences Center, the group charged with oversight of the state’s 10 year, $ 1 billion investment in the life sciences.
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Pharmaceuticals. He has testified as an expert witness in several high- profile biotechnology patent trials in
Federal Court, notably Amgen vs. TKT Aventis in 2000, Amgen vs. Roche in 2009, and Biogen vs. Merck - Serono in 2018; he was on the winning side in all.
473:(formerly Acrp30). These have been used to define the structure, biosynthesis, and cellular functions of these and related proteins and to identify and characterize related genes that encode proteins with important physiological functions.
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426:. Beginning in 1973, his laboratory has concentrated on the biogenesis, structure, and function of several important secreted and plasma membrane glycoproteins. He defined the biosynthesis and maturation of the
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538:, and a Foreign Member of the Royal Academy of Medicine of Belgium. Dr. Lodish received a MERIT award from the National Institute of Diabetes and Digestive and Kidney Diseases. He is also a recipient of a
438:, and clarified the role of pH changes in delivery of iron to cells and recycling of the transferrin receptor. His group has elucidated steps in folding and oligomerization of several proteins within the
483:– activation of and signal transduction by the erythropoietin receptor in erythroid progenitor cells, and the regulation of transcription, apoptosis, cell division, and enucleation during erythropoiesis.
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442:, showed that exit of newly made proteins from this organelle requires that they be properly folded, and developed probes for measurement of the redox state within the endoplasmic reticulum.
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course "Science and
Business of Biotechnology" to over 80 MIT graduate students. The version he taught in 2019 is on line as an MIT EdX course and has enrolled over 28,000 students:
319:(winner of the Nobel Prize in Physiology or Medicine, 1975). In 1999, Dr. Lodish also became Professor of Biological Engineering in the new MIT Department of Biological Engineering.
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Dr. Lodish is the lead author of the textbook
Molecular Cell Biology. The ninth edition was published in 2021 and the book has been translated into fourteen languages.
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He is the recipient of honorary
Doctorate of Science degrees from Kenyon College, the Chinese University of Hong Kong, and Case Western Reserve University.
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He has served on the
Scientific Advisory Board for the Eisai Research Institute in Massachusetts and on the Scientific Advisory Board of Astra and then
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Initially, Dr. Lodish's work focused on translational control of protein synthesis and on development of the cellular slime mold
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307:(winners of the Nobel Prize in Physiology or Medicine, 2002 and 1962, respectively), he joined the faculty of the
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in
Heidelberg, the Center for Molecular Biology Heidelberg (ZMBH) in Germany, the Life Sciences Institute of the
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and other plasma membrane glycoproteins, identified the intracellular organelles that mediate recycling of the
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His research group was the first to clone and sequence mRNAs encoding a mammalian glucose transport protein,
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and Long non-Coding RNAs in regulating hematopoiesis and fat and muscle cell development and metabolism
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354:, and the PEW Scholars Program in Biomedical Sciences. He has served on the Visiting Committees of the
342:. He has served on the advisory boards of several other institutions, including the Biozentrum of the
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Two former postdoctoral researchers in Dr. Lodish's laboratory have gone on to win Nobel Prizes:
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In 1963 he married Pamela
Chentow. They have three married children and seven grandchildren.
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He closed his laboratory in 2019; the most recent efforts of his group were focused on:
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742:"Dr. Harvey Lodish: Founding Member, Whitehead Institute - DARPA BIT Keynote Speaker"
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Dr. Lodish received his A.B. degree Summa Cum Laude and with
Highest Honors in
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334:. He was Chair of the advisory board of the Division of Basic Sciences of the
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From 1989 through 2007 Dr. Lodish was a member of the Board of
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During the 2004 calendar year Dr. Lodish served as president of the
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Dr. Lodish was a founder and scientific advisory board member of
772:. HKUST Jockey Club Institute for Advanced Study. June 19, 2020.
754:"History of Whitehead Institute by Harvey Lodish (May 25, 2018)"
766:"IAS Distinguished Lecture: Prof Harvey F Lodish (19 Jun 2018)"
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760:. Whitehead Institute for Biomedical Research. July 17, 2018.
591:"Translational Control of Protein Synthesis: The Early Years"
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Division of Biology and of the Engineering Division of the
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Members of the United States National Academy of Sciences
786:(Introduction by Gene Brown, talk on December 17, 2008)
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Dr. Lodish has served on advisory panels for the U.S.
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the Lodish Lab, Massachusetts Institute of Technology
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Fellows of the American Academy of Arts and Sciences
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American Association for the Advancement of Science
372:Dr. Lodish is a member of the Board of Trustees of
280:in 1962, and his Ph.D. degree in genetics with Dr.
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726:MIT Department of Biological Engineering homepage
784:. MIT Department of Biology. August 24, 2020.
560:Bard Lecture, Johns Hopkins University (2008)
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338:and of the Lerner Research Institute of the
313:Whitehead Institute for Biomedical Research
242:Whitehead Institute for Biomedical Research
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69:Learn how and when to remove this message
369:, and currently is an Emeritus Trustee.
32:This article includes a list of general
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536:European Molecular Biology Organization
534:, an Associate (Foreign) Member of the
360:University of California Santa Barbara
528:American Academy of Arts and Sciences
348:European Molecular Biology Laboratory
238:Massachusetts Institute of Technology
7:
393:, Inc., Arris Pharmaceuticals, Inc,
778:"A Conversation with Harvey Lodish"
595:The Journal of Biological Chemistry
188:MRC Laboratory of Molecular Biology
721:MIT Department of Biology homepage
356:California Institute of Technology
244:, and lead author of the textbook
38:it lacks sufficient corresponding
16:American cell biologist, born 1941
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815:MIT School of Engineering faculty
384:American Society for Cell Biology
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589:Lodish, Harvey F. (2012-10-19).
532:American Academy of Microbiology
288:in 1966. Following two years of
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297:Laboratory of Molecular Biology
248:. Lodish's research focused on
518:Dr. Lodish is a Member of the
240:(MIT), Founding Member of the
228:(born November 16, 1941) is a
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855:University of Michigan people
830:American molecular biologists
820:Rockefeller University alumni
336:Fred Hutchinson Cancer Center
324:National Institutes of Health
731:Whitehead Institute homepage
520:National Academy of Sciences
453:and the insulin- responsive
850:Whitehead Institute faculty
328:National Science Foundation
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428:vesicular stomatitis virus
395:Millennium Pharmaceuticals
374:Boston Children’s Hospital
748:. DARPAtv. June 26, 2015.
499:Elucidating the roles of
309:MIT Department of Biology
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835:American cell biologists
487:Hematopoietic stem cells
423:Dictyostelium discoideum
608:10.1074/jbc.X112.420356
463:erythropoietin receptor
332:American Cancer Society
53:more precise citations.
552:(Chemistry, 2004) and
465:, two subunits of the
352:University of Michigan
286:Rockefeller University
254:molecular cell biology
246:Molecular Cell Biology
226:Harvey Franklin Lodish
149:Rockefeller University
825:Kenyon College alumni
540:Guggenheim Fellowship
440:endoplasmic reticulum
436:transferrin receptors
416:Research and Teaching
315:by Founding Director
290:postdoctoral research
250:cell surface proteins
214:Lydia Villa-Komaroff
736:Lodish Lab homepage
601:(43): 36528–36535.
344:University of Basel
236:, professor at the
180:Whitehead Institute
705:has a profile for
530:, a Fellow of the
526:, a Fellow of the
432:asialoglycoprotein
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492:The functions of
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160:Scientific career
113:November 16, 1941
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805:1941 births
494:adiponectin
471:adiponectin
449:, and then
406:AstraZeneca
274:Mathematics
135:Citizenship
127:Nationality
51:introducing
794:Categories
710:(Q5677403)
659:2020-01-24
649:"Founders"
565:References
459:isomaltase
299:with Drs.
109:1941-11-16
34:references
617:0021-9258
501:microRNAs
284:from the
270:Chemistry
264:Biography
230:molecular
635:22988251
399:Allozyne
397:, Inc,
330:and the
258:medicine
130:American
782:YouTube
770:YouTube
758:YouTube
746:YouTube
703:Scholia
626:3476319
391:Genzyme
292:at the
276:, from
47:improve
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514:Awards
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346:, the
294:M.R.C.
166:Fields
36:, but
455:GLUT4
451:GLUT2
447:GLUT1
631:PMID
613:ISSN
434:and
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