Healthier Lives - Knowledge (XXG)

737: 197: 174: 800: 309:, which together account for one third of total death and disability in New Zealand. At the time of establishment, the stated goal of Healthier Lives was to reduce the overall burden of these diseases on New Zealand's health system by 25% by the year 2025. At the halfway point HLNSC underwent a public consultation process and a research review by six international scientists to develop its 2019–2014 research strategy. This strategy addressed three areas: precision medicine for cancer and cardiovascular disease; culturally-centred health programmes for 506: 31: 338: 663: 650: 460: 410: 764:, commissioned by Healthier Lives, the Edgar Diabetes and Obesity Research Centre, Diabetes New Zealand and philanthropists Tony and Heather Falkenstein, estimated that the number of New Zealanders with type 2 diabetes would increase by 70–90% by 2040 and examined the projected economic and social costs. Healthier Lives called on the Government to develop a national strategy for tackling type 2 diabetes. In 2023, 679:. The HYPE team examined nine organisations that had adopted the policy but found none met its criteria, though the food and drink they had available for sale was healthier than organisations which had not adopted the policy. They concluded the voluntary policy was ineffective, recommended a mandatory one be adopted, and developed new resources to support implementation of this policy in the public sector. 389:

disease than Pākehā, but Chinese and other Asian New Zealanders had a 25–33% lower risk. The research replaced risk prediction equations developed from a much earlier US study of just 5,000 people which significantly overestimated risk for the healthy majority, while underestimating risk factors in others, potentially leading to under-treatment of vulnerable, high-risk groups. The

317:; and healthy food and physical activity environments. The use of big and linked data to answer health questions was also a focus of research. At the end of the review, MBIE commented that HLNSC had "developed exemplary methods of community engagement, and has co-created 40% of its research with stakeholders, which means implementation of research is more likely." 703:

date of birth, or sex incorrectly match records; when these errors are correlated with ethnicity, linkage bias can occur. A HLNSC project led by Andrea Teng developed a guide for health researchers on linkage bias in the IDI. The team also examined how to link community lab information to the wider health system, using a dataset of ten years of test results for

605: 481:, and two studies addressed this. One qualitative study, the Pasifika Prediabetes Youth Empowerment Programme (PPYEP) worked with Pasifika youth and adults to reduce risk factors for prediabetes. Another community-led study, Oire Tokoroa, successfully worked with 20 families in the Pacific community in 472:

Te Kāika DiRECT, a randomised controlled trial of 40 participants, most Māori or Pasifika, with prediabetes or type 2 diabetes, examined the effectiveness of a total three-month meal replacement regime and behavioural support for weight loss; the results suggested it was a non-surgical alternative to

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arrangement with the Governance Group, to be trialled for a year; HLNSC thus became the first National Science Challenge to adopt co-governance. A review in May 2018 endorsed the co-governance arrangement and in February 2019 it was formalised in the Collaboration Agreement with other institutions. A

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with Māori and Pacific community leaders and researchers, Heathier Lives funded research to reduce health inequities: co-designed and community-led healthcare programmes; an Implementation Network to assist the uptake of these research programmes; and initiatives to create systemic change in the New

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was appointed the first Chair of the 7-member Governance Group for Healthier Lives, which held its first full meeting on 27 October 2015. In August 2015 MBIE approved funding for the Heathier Lives National Science Challenge (HLNSC), with a budget of $ 31.26 million over 10 years. Additional funding

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makes large amounts of anonymised data available for analysis through its Integrated Data Infrastructure (IDI). However two problems make this data less useful for health research: a lack of primary care data, and linkage bias. Linkage errors happen when probabilistic linking of data through name,

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in partnership with Māori health providers Te Kōhao Health and Poutiri Charitable Trust developed a set of guidelines for health interventions with Māori communities – the He Pikinga Waiora Implementation Framework –based on building relationships and co-designing the way health interventions are

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created new and more accurate equations for predicting the risk of cardiovascular disease. The clinical study of 400,000 New Zealanders aged 30–74 revealed differences in risk from socioeconomic factors and ethnicity: Māori, Pacific, and Indian patients had a 13–48% greater risk of cardiovascular

756:

in preventing and treating non-communicable diseases; it also identified the need for a national nutrition survey to inform New Zealand health research and policy. In October 2021, the Ministry of Health commissioned a team at the National Institute for Health Innovation, led by Healthier Lives

2484:

The Diabetes and Nutrition Study Group (DNSG) of the European Association for the Study of Diabetes (EASD); Aas, Anne-Marie; Axelsen, Mette; Churuangsuk, Chaitong; Hermansen, Kjeld; Kendall, Cyril W. C.; Kahleova, Hana; Khan, Tauseef; Lean, Michael E. J.; Mann, Jim I.; Pedersen, Eva; Pfeiffer,

1748:

Firestone, Ridvan; Faeamani, Gavin; Okiakama, Elizabeth; Funaki, Tevita; Henry, Akarere; Prapaveissis, Danielle; Filikitonga, Jennifer; Firestone, Justice; Tiatia-Seath, Jemaima; Matheson, Anna; Brown, Blakely; Schleser, Max; Kaholokula, Joseph Keawe‘aimoku; Ing, Claire; Borman, Barry (2021).

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clinics. Another project, Manawataki Fatu Fatu, led by Corina Grey and Matire Harwood and co-funded by the Heart Foundation, studied gaps in the assessment, care, and management of cardiovascular disease in Māori and Pacific communities. They found that improved hospital discharge summaries

779:, highlighted the frustration of health researchers with the slow uptake of research evidence to improve the health of New Zealanders. The report, which arose from a public webinar held on 17 November 2021, suggested ways of strengthening the pathway between research and its application. 1790:

Prapaveissis, Danielle; Henry, Akerere; Okiakama, Elizabeth; Funaki, Tevita; Faeamani, Gavin; Masaga, Jennifer; Brown, Blakely; Kaholokula, Keawe; Ing, Claire; Matheson, Anna; Tiatia-Seath, Jemaima; Schleser, Max; Borman, Barry; Ellison-Loschmann, Lis; Tupai-Firestone, Ridvan (2022).

2106:

Verbiest, Marjolein E A; Corrigan, Callie; Dalhousie, Sally; Firestone, Ridvan; Funaki, Tevita; Goodwin, Debbie; Grey, Jacqui; Henry, Akarere; Humphrey, Gayl; Jull, Andrew; Vano, Mereaumate; Pekepo, Crystal; Morenga, Lisa Te; Whittaker, Robyn; Mhurchu, Cliona Ni (16 July 2019).

636:

emissions and freshwater contamination, as well as minimising the financial impact on families and farmers. Related research led by Andrew Reynolds modelled five scenarios for replacing red meat in the New Zealand diet and found significant benefits associated with all of them.

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established five research projects with a total budget of $ 7.9 million, and a partnership equally funded by HLNSC and the Heart Foundation supported a $ 2 million three-year study, Manawataki Fatu Fatu, on cardiovascular disease inequities amongst Māori and Pasifika.

1262:

Fitzgerald, Sandra; Blenkiron, Cherie; Stephens, Rosalie; Mathy, Jon A.; Somers-Edgar, Tiffany; Rolfe, Gill; Martin, Richard; Jackson, Christopher; Eccles, Michael; Robb, Tamsin; Rodger, Euan; Lawrence, Ben; Guilford, Parry; Lasham, Annette; Print, Cristin G. (2023).

2064:

Te Morenga, Lisa; Pekepo, Crystal; Corrigan, Callie; Matoe, Leonie; Mules, Rangimarie; Goodwin, Debbie; Dymus, Janelle; Tunks, Megan; Grey, Jacqui; Humphrey, Gayl; Jull, Andrew; Whittaker, Robyn; Verbiest, Marjolein; Firestone, Ridvan; Ni Mhurchu, Cliona (2018).

540:, addressed ethnic health inequities by developing an equity-focussed implementation framework (FrEEIA) and equity readiness assessment tool for mainstream health interventions – the first adapted for a New Zealand context – which was trialled in a three-year 682:

Karen Witten and colleagues undertook the ACTIVATION research programme, which looked at encouraging active transport — walking and cycling – and improving community infrastructure to reduce car dependence. Researchers examined barriers to active mobility in

691:, and how housing and transport design could encourage active transport. A study of the effect of the 2022–2023 half-price bus fares in Christchurch found 45% of lower-income residents had been able to afford additional trips and more food and essentials. 1949:

Grey, Corina; Brewer, Karen Marie; Ameratunga, Shanthi; Selak, Vanessa; Hanchard, Sandra; Dicker, Bridget; Paynter, Janine; Taueetia-Su’a, Tua; Winter-Smith, Julie; Newport, Rochelle; Tane, Taria; Harwood, Matire Louise Ngarongoa (2023).

1320:

Pylypchuk, Romana; Wells, Sue; Kerr, Andrew; Poppe, Katrina; Riddell, Tania; Harwood, Matire; Exeter, Dan; Mehta, Suneela; Grey, Corina; Wu, Billy P; Metcalf, Patricia; Warren, Jim; Harrison, Jeff; Marshall, Roger; Jackson, Rod (2018).

1615:"A case study of using the He Pikinga Waiora Implementation Framework: challenges and successes in implementing a twelve-week lifestyle intervention to reduce weight in Māori men at risk of diabetes, cardiovascular disease and obesity" 535:

providers and researchers, the Healthier Lives Implementation Network, was set up to translate research into practice and better meet the health needs of Māori and Pacific communities. The Health Systems Change project, led by

790:

and an accompanying short guide. The report offered an evidence-based approach for co-designing research with Māori and Pacific communities, and a benchmark for assessing the integrity of future co-designed research projects.

627:), when modelled, was no more expensive than current diets, halved associated greenhouse gas emissions, and provided large health gains, cost savings and reductions in ethnic health inequities. Collaborative research with the 324:. Māori life expectancy is seven years shorter than Pākehā, and Pasifika six years; the life expectancy gap is not closing for Pasifika and increasing rates of diabetes means it is likely to widen. After consultation and 189:: large multi-year collaborative research programmes that would address important issues in New Zealand's future. The funding criteria were set out in January 2014, with proposals assessed by a Science Board within the 447:

carried out. The Framework was used to co-design two health programmes, one targeting Māori men at risk of diabetes, cardiovascular disease and obesity, and the other, Kimi Ora, a healthy lifestyle intervention.

2223:

Gustafson, Papillon; Abdul Aziz, Yasmin; Lambert, Michelle; Bartholomew, Karen; Rankin, Nicole; Fusheini, Adam; Brown, Rachel; Carswell, Peter; Ratima, Mihi; Priest, Patricia; Crengle, Sue (16 October 2023).

2707: 631:

National Science Challenge modelled the changes in New Zealand land use that would produce food for this optimised healthy diet, and found that it would be possible to feed all New Zealanders while reducing

2340:

Gustafson, Papillon; Lambert, Michelle; Bartholomew, Karen; Ratima, Mihi; Aziz, Yasmin Abdul; Kremer, Lisa; Fusheini, Adam; Carswell, Peter; Brown, Rachel; Priest, Patricia; Crengle, Sue (27 January 2024).

1214:

Zou, Donghui; Day, Robert; Cocadiz, Judy A; Parackal, Sarah; Mitchell, Wilson; Black, Michael A; Lawrence, Ben; Fitzgerald, Sandra; Print, Cristin; Jackson, Christopher; Guilford, Parry (13 November 2020).

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The Mana Tū project, initiated by the National Hauora Coalition, which set up a network of community health workers and GPs to support Māori and Pacific people living with type 2 diabetes, was evaluated by

1691:"Experiences and Acceptability of a Weight Loss Intervention for Diabetes (Diabetes Remission Clinical Trial—DiRECT) in Aotearoa New Zealand: A Qualitative Study within a Pilot Randomised Controlled Trial" 1664: 520:

OL@-OR@, a mobile-phone (app and website) delivering lifestyle support programme for Māori and Pasifika, was co-designed and evaluated in a partnership between a team of university researchers led by

493:. The three-year trial studied the effectiveness of training healthcare navigators/kaimanaaki (social workers, nurses, and receptionists) to work with diabetes patients, with 400 participants over 10 736: 434:, can be altered by cardiovascular disease. Jones's team developed a risk model based on DNA methylation profiles of people with heart disease, combined with genetic markers and known risk factors. 320:

New Zealand has significant health inequities, with Māori having 1.8 times higher rates of cardiovascular disease mortality than non-Māori, and Pasifika 9.1 times the mortality rates of Pākehā from

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in the New Zealand population, encompassing prevention, treatment, and the reduction of health inequity, and including precision medicine techniques, and culturally-centred health programmes for

2283:

Gustafson, Papillon; Aziz, Yasmin Abdul; Lambert, Michelle; Bartholomew, Karen; Brown, Rachel; Carswell, Peter; Fusheini, Adam; Ratima, Mihi; Priest, Patricia; Crengle, Sue (1 February 2023).

675:

The HYPE (Healthy Policy Evaluation) project, led by Clíona Ní Mhurchú, examined the voluntary National Healthy Food and Drink Policy developed for public sector organisations such as

2166:"Healthier Lives Implementation Research Network for Māori and Pacific community health providers in Aotearoa New Zealand: a study protocol with an observational mixed methods design" 3560: 3475: 3078: 1952:"Manawataki Fatu Fatu for ACCESS (Māori and Pacific Hearts in Unison for Achieving Cardiovascular Care in Equity StudieS). Protocol for a Mixed Methods Programme of Research" 393:

adopted the new equations into its 2018 guidelines and issued a new data standard, which was incorporated into MedTech, the medical records system widely used by New Zealand

281:

single 8-member entity, the Governance Group and Kāhui Māori, was established. In 2020 at the end of the first 5-year funding period Jennifer McMahon stepped down, and Sir

2226:"A scoping review of equity-focused implementation theories, models and frameworks in healthcare and their application in addressing ethnicity-related health inequities" 1868:"Indigenous health worker support for patients with poorly controlled type 2 diabetes: study protocol for a cluster randomised controlled trial of the Mana Tū programme" 2882: 720:

to answer health questions: one looked at the rates of cardiovascular disease following the Canterbury earthquakes, another at the factors affecting the progression of

3345: 246: 190: 106: 196: 2109:"Using codesign to develop a culturally tailored, behavior change mHealth intervention for indigenous and other priority communities: A case study in New Zealand" 3449: 2460:

Saturated fat and trans-fat intakes and their replacement with other macronutrients: a systematic review and meta-analysis of prospective observational studies

2285:"Supporting implementation of interventions to address ethnicity-related health inequities: frameworks, facilitators and barriers – a scoping review protocol" 3423: 1992: 1372: 3051: 173: 3501: 1689:

Campbell, Kate; Peddie, Meredith; Ashton, Natalie; Ma’ia’i, Kim; Russell-Camp, Takiwai; Mann, Jim; Camp, Justine; Reynolds, Andrew N. (13 June 2024).

2017:

Chan, Daniel Zl; Grey, Corina; Doughty, Rob N.; Lund, Mayanna; Lee, Mildred Ai Wei; Poppe, Katrina; Harwood, Matire; Kerr, Andrew (29 January 2024).

3371: 1425: 799: 973: 250: 210: 1026: 3523: 2468: 1531: 1435: 1408: 900: 849: 2907:

Thorne, Rebekah; Fanueli, Elizabeth; Wild, Kirsty; Raja, Ali; Witten, Karen; Mackie, Hamish; Woodward, Alistair; Hirsch, Lily (3 May 2024).

2651:"The neglected potential of red and processed meat replacement with alternative protein sources: Simulation modelling and systematic review" 1398: 3605: 3600: 345:

Healthier Lives supported the development of precision medicine techniques, for example using tumour-derived DNA circulating in the blood (

2343:"Adapting an equity-focused implementation process framework with a focus on ethnic health inequities in the Aotearoa New Zealand context" 1751:"Pasifika prediabetes youth empowerment programme: evaluating a co-designed community-based intervention from a participants' perspective" 3185:"Living in areas with different levels of earthquake damage and association with risk of cardiovascular disease: a cohort-linkage study" 1198: 1178: 588:. These findings contributed to updated European guidelines for dietary management of diabetes, including the possibility of reversing 3131: 2749:"Tools and resources used to support implementation of workplace healthy food and drink policies: A scoping review of grey literature" 1554:

Oetzel, John; Scott, Nina; Hudson, Maui; Masters-Awatere, Bridgette; Rarere, Moana; Foote, Jeff; Beaton, Angela; Ehau, Terry (2017).

1323:"Cardiovascular disease risk prediction equations in 400 000 primary care patients in New Zealand: a derivation and validation study" 1081: 2706:

Ni Mhurchu, Cliona; Gerritsen, Sarah; Kidd, Bruce; Rosin, Magda; Shen, Stephanie; Mackay, Sally; Te Morenga, Lisa (19 August 2022).

270: 242: 864: 841:

Pathways between research policy and practice for equitable evidence-informed health and wellbeing in Aotearoa's new health system

1866:

Selak, Vanessa; Stewart, Tereki; Jiang, Yannan; Reid, Jennifer; Tane, Taria; Carswell, Peter; Harwood, Matire (1 December 2018).

390: 214: 2600:

McDowell, Richard W.; Herzig, Alexander; van der Weerden, Tony J.; Cleghorn, Christine; Kaye-Blake, William (23 November 2022).

814: 205: 528:, and Rivdan Firestone, and community providers Toi Tangata, The Fono, and South Waikato Pacific Islands Community Services. 1665:"He Pikinga Waiora Kimi Ora lifestyle programme: case study of a successful community-based Indigenous diabetes intervention" 3250:

Teng, Andrea; Blakely, Tony; Scott, Nina; Jansen, Rawiri; Masters-Awatere, Bridgette; Krebs, Jeremy; Oetzel, John (2019).

1924: 840: 772:

established a working group, co-chaired by Healthier Lives director Jim Mann, to develop a National Diabetes Action Plan.

885:. This report, initiated by Healthier Lives, summarised research from three Science Challenges for health system leaders. 1512:"Data Analysis of DNA Methylation Epigenome-Wide Association Studies (EWAS): A Guide to the Principles of Best Practice" 1217:"Circulating tumor DNA is a sensitive marker for routine monitoring of treatment response in advanced colorectal cancer" 688: 385: 3396: 3252:"What protects against pre-diabetes progressing to diabetes? Observational study of integrated health and social data" 999: 485:

to help those with prediabetes or type 2 diabetes make healthier lifestyle choices, including developing a cookbook.

186: 138: 2602:"Growing for good: producing a healthy, low greenhouse gas and water quality footprint diet in Aotearoa, New Zealand" 609: 505: 2947: 2561:"Assessing the Health and Environmental Benefits of a New Zealand Diet Optimised for Health and Climate Protection" 1793:"Assessing youth empowerment and co-design to advance Pasifika health: a qualitative research study in New Zealand" 1556:"Implementation framework for chronic disease intervention effectiveness in Māori and other indigenous communities" 823: 3476:"NZ's evidence-based response to COVID has saved lives – we could do better when it comes to other major diseases" 2457:

Reynolds, Andrew N.; Hodson, Leanne; de Souza, Russell; Tran Diep Pham, Huyen; Vlietstra, Lara; Mann, Jim (2022).

728:

is associated with a reduced risk of progression), and a third estimated the prevalence of cancer in New Zealand.

521: 509: 3503:

Co-designing health research in Aotearoa New Zealand: Lessons from the Healthier Lives National Science Challenge

2948:"(Un)successful Urban Regeneration and Wellbeing Inter-Sector Collaboration in a Regenerating Post-Disaster City" 1151: 891:

Co-designing health research in Aotearoa New Zealand: Lessons from the Healthier Lives National Science Challenge

443: 422:

Another approach to predicting risk of cardiovascular disease was developed by a team led by Greg T. Jones using

3224: 1106: 752:

symposium co-hosted in Dunedin by Healthier Lives in February 2019 presented the latest research on the role of

687:, and how these could be overcome. In Christchurch, they studied the growth of inner-city housing following the 3077:

Curl, Angela; Coppens, Anna; Dares, Cushla; Williman, Jonathan; Fitt, Helen; Kingham, Simon (2 February 2024).

1840: 262: 2909:"'Everyone rides together, everyone rolls together': exploring walking and cycling cultures in South Auckland" 1055: 314: 162: 3305:

Brewer, Naomi; Teng, Andrea; Atkinson, June; Guilford, Parry; Print, Cristin; Blakely, Tony (8 May 2020).

699: 585: 552:

Research by Andrew Reynolds and colleagues established the evidence for the health benefits of increasing

499: 298: 258: 146: 948: 676: 624: 378: 346: 266: 2883:"Don't believe the backlash – the benefits of NZ investing more in cycling will far outweigh the costs" 3079:"Accessibility and Affordability Impacts of Half Price Public Transport Fares in Aotearoa New Zealand" 2708:"2021 assessment of New Zealand district health boards' institutional healthy food and drink policies" 835:. A list of the 15 New Zealand Government policies relevant to the Healthier Lives research programme. 30: 3023: 2970: 2908: 1750: 394: 222: 83: 2400:

Reynolds, Andrew; Mann, Jim; Cummings, John; Winter, Nicola; Mete, Evelyn; Te Morenga, Lisa (2019).

1453:"A validated restriction enzyme ddPCR cg05575921 (AHRR) assay to accurately assess smoking exposure" 1424:

Health Information Standards Organisation (HISO), Manatū Hauora - Ministry of Health (31 May 2019).

3183:

Teng, Andrea M; Blakely, Tony; Ivory, Vivienne; Kingham, Simon; Cameron, Vicky (1 September 2017).

873: 705: 623:

found that a New Zealand version of a sustainable healthy diet (based on the EAT-Lancet Commission

577: 573: 532: 234: 498:(especially for heart failure) and recruitment, retention, and support for the Māori and Pasifika 141:. Running from 2015 to 2024, the focus of Healthier Lives National Science Challenge research was 3287: 3011: 2631: 2439: 2067:"Co-designing an mHealth tool in the New Zealand Māori community with a "Kaupapa Māori" approach" 1350: 628: 96: 2164:

Oetzel, John; Sika-Paotonu, Dianne; Penetito-Hemara, Darrio; Henry, Akarere (22 November 2022).

226: 592:

through weight loss, and World Health Organization guidelines on dietary carbohydrate and fat.

337: 200:

The Healthier Lives Governance Group and Science Leadership Team at its launch in December 2015

3519: 3326: 3318: 3279: 3271: 3206: 3115: 3096: 2992: 2928: 2837: 2819: 2778: 2770: 2748: 2729: 2688: 2670: 2623: 2582: 2516: 2508: 2464: 2431: 2423: 2382: 2364: 2322: 2304: 2265: 2247: 2205: 2187: 2146: 2138: 2088: 2046: 2038: 1973: 1905: 1887: 1822: 1772: 1730: 1712: 1646: 1595: 1577: 1537: 1527: 1492: 1474: 1431: 1404: 1342: 1302: 1284: 1244: 1236: 896: 845: 620: 513: 354: 254: 225:

was appointed as director of Healthier Lives, and the programme was launched at a ceremony at

3424:"COVID-19 urgency needed to address an "avalanche of diabetes" amongst the Pacific community" 1216: 3529: 3511: 3263: 3196: 3086: 3031: 3012:"Considering the importance of transport to the wellbeing of Māori social housing residents" 2982: 2920: 2827: 2809: 2760: 2719: 2678: 2662: 2613: 2572: 2498: 2413: 2372: 2354: 2312: 2296: 2255: 2237: 2195: 2177: 2128: 2120: 2078: 2030: 1963: 1951: 1895: 1879: 1812: 1804: 1762: 1720: 1702: 1636: 1626: 1585: 1567: 1519: 1482: 1464: 1334: 1292: 1276: 1228: 877: 828: 783: 494: 3554: 1518:, Methods in Molecular Biology, vol. 2458, New York, NY: Springer US, pp. 23–45, 3157: 769: 589: 525: 477:-supported care programme. The prevalence of type 2 diabetes in Pasifika is twice that of 431: 374: 321: 282: 230: 3565: 3397:"Parliamentary launch: The Economic and Social Cost of Type 2 Diabetes - Healthier Lives" 3132:"Big data for tackling non-communicable diseases and health inequities - Healthier Lives" 2402:"Carbohydrate quality and human health: a series of systematic reviews and meta-analyses" 757:

deputy director Clíona Ní Mhurchú, to develop the methods and tools for the next survey.

725: 414:

Developing precise and equitable cardiovascular disease risk prediction tools in Aotearoa

310: 158: 3027: 2832: 2797: 2458: 2377: 2342: 2260: 2225: 1725: 1690: 1511: 1487: 1452: 1297: 1264: 1203:. Association of Salaried Medical Specialists and the Canterbury Charity Hospital Trust. 2683: 2650: 2317: 2200: 2165: 2108: 1900: 1817: 1792: 1641: 1614: 1613:

Oetzel, John; Rarere, Moana; Wihapi, Ray; Manuel, Carey; Tapsell, Jade (22 June 2020).

1590: 1555: 1451:

Fitzgerald, Sandra; Bhat, Basharat; Print, Cristin; Jones, Gregory T. (25 March 2024).

1265:"Dynamic ctDNA Mutational Complexity in Patients with Melanoma Receiving Immunotherapy" 1197:

Association of Salaried Medical Specialists; Canterbury Charity Hospital Trust (2021).

710: 684: 633: 557: 490: 366: 3201: 3184: 3010:

Russell, Els; McKerchar, Christina; Berghan, James; Curl, Angela; Fitt, Helen (2024).

2418: 2401: 1338: 276:

A 4-member Kāhui Māori group was established in 2016, and on 19 October it proposed a

3594: 2635: 753: 569: 553: 362: 277: 3291: 2969:

Russell, Els; McKerchar, Christina; Thompson, Lee; Berghan, James (2 October 2023).

2443: 1510:

Bhat, Basharat; Jones, Gregory T. (2022), Horsfield, Julia; Marsman, Judith (eds.),

1373:"Māori, Pasifika and South Asians at greater risk of cardiovascular disease - study" 1354: 237:

was chosen to host HLNSC, with other research partners around New Zealand including

3307:"An estimate of limited duration cancer prevalence in New Zealand using 'big' data" 974:"Multi-million dollar funding collaboration to improve long-term health conditions" 765: 581: 178: 3267: 2987: 2924: 2618: 2601: 1767: 1107:"Sir Jerry Mateparae to lead the Healthier Lives Governance Group and Kāhui Māori" 832: 786:

evaluation of several Healthier Lives co-designed projects led to the 2024 report

478: 2666: 2649:

Reynolds, Andrew N.; Mhurchu, Cliona Ni; Kok, Zi-Yi; Cleghorn, Christine (2023).

2034: 713:

which has significantly different death rates across ethnicities in New Zealand.

3450:"Type 2 diabetes to become epidemic that will 'bankrupt' health system — expert" 3251: 2487:"Evidence-based European recommendations for the dietary management of diabetes" 2300: 1993:"Pacific Research Fellowship winner excited to spread early heart check message" 1883: 1523: 1322: 860: 721: 561: 541: 537: 423: 370: 134: 3052:"Cheaper public transport trial helped people experiencing 'transport poverty'" 2503: 2486: 2359: 2284: 2242: 2182: 1867: 1631: 1469: 1280: 921: 177:

Walking onto Ōtākou marae at the launch of Healthier Lives on 4 December 2015,

3036: 2855: 2534: 1968: 1572: 890: 666: 653: 463: 413: 350: 325: 238: 3322: 3275: 3100: 2996: 2932: 2823: 2774: 2674: 2627: 2586: 2512: 2427: 2368: 2308: 2251: 2191: 2142: 2092: 2083: 2066: 2042: 1977: 1891: 1776: 1716: 1581: 1478: 1288: 1240: 1232: 1180:

National Science Challenges: Science Board decisions on second period funding

922:"Criteria for Proposals for National Science Challenges funding - 2014-go548" 724:

to type 2 diabetes in New Zealand (including the novel finding that speaking

3533: 3306: 2765: 2018: 1808: 881: 565: 474: 3330: 3283: 3210: 2841: 2782: 2733: 2692: 2520: 2435: 2386: 2326: 2269: 2209: 2150: 2050: 1909: 1826: 1734: 1650: 1599: 1541: 1496: 1346: 1306: 1248: 430:

from environmental factors such as smoking. One type of epigenetic change,

3372:"Numbers with type 2 diabetes could almost double in two decades - report" 1186:. Wellington: Ministry of Business, Innovation, and Employment. p. 6. 2124: 717: 358: 329:

Zealand health system to support equitable outcomes from new programmes.

306: 293:

The focus of Heathier Lives was four chronic, non-communicable diseases:

154: 16:

Collaborative public health research programme in New Zealand (2015–2024)

3091: 2577: 2560: 361:, both prevalent in New Zealand, and the technology is being applied to 209:

came from collaborations: the Long Term Conditions partnership with the

3515: 2814: 2724: 1707: 482: 302: 150: 2133: 2019:"Widening ethnic inequities in heart failure incidence in New Zealand" 1400:

Cardiovascular Disease Risk Assessment and Management for Primary Care

1138:

Heathier Lives National Science Challenge Research Strategy 2019–2024

815:

Heathier Lives National Science Challenge Research Strategy 2019–2024

294: 142: 1427:

HISO 10071:2019 Cardiovascular Disease Risk Assessment Data Standard

1200:

Creating Solutions Te Ara Whai Tika: A roadmap to health equity 2040

2535:"The EAT-Lancet Commission on Food, Planet, Health - EAT Knowledge" 2485:

Andreas; Rahelić, Dario; Reynolds, Andrew N.; Risérus, Ulf (2023).

1140:. Dunedin: Department of Medicine, University of Otago. June 2019. 838:

Mann, J., Cockram, J., Glen, J., and Stayner, C. (November 2022).

803:

Healthier Lives Governance Group and Kāhui Māori at the launch of

798: 735: 669:(Feb 2024 presentation by Karen Witten, Simon Kingham, and others) 504: 336: 195: 172: 3575: 3570: 3550: 502:

workforce were needed to reduce inequities in heart healthcare.

2559:

Cleghorn, Christine; Nghiem, Nhung; Ni Mhurchu, Cliona (2022).

844:. Healthier Lives–He Oranga Hauora National Science Challenge. 341:

Tanis Godwin, Parry Guilford, and Donghui Zou in Guilford's lab

117: 3580: 2971:"Māori experiences of social housing in Ōtautahi Christchurch" 2798:"Meat-Free Mondays in Hospital Cafés in Aotearoa, New Zealand" 427: 3346:"Comment: Time for a check-up on Kiwis' latest eating habits" 827:. Auckland: Public Policy Institute, University of Auckland. 821:

Leakey, C.J., Curtin, J., and Greaves, L.M. (24 March 2022).

895:

Healthier Lives–He Oranga Hauora National Science Challenge

824:

Healthier Lives National Science Challenge: Policy Inventory

2071:

AlterNative: An International Journal of Indigenous Peoples

866:

Evidence for Health and Wellbeing in Aotearoa New Zealand

656:(A Feb 2024 discussion with Clíona Ní Mhurchú and others) 185:

The New Zealand Government agreed in August 2012 to fund

2747:

Rosin, Magda; Mackay, Sally; Ni Mhurchu, Cliona (2023).

888:

Goodwin, Debbie & Boulton, Amohia. (February 2024).

564:. Their work also supported the importance of replacing 2975:

Kōtuitui: New Zealand Journal of Social Sciences Online

1755:

Kōtuitui: New Zealand Journal of Social Sciences Online

1000:"New research projects for long-term health conditions" 818:. Dunedin: Department of Medicine, University of Otago. 438:

Culturally-centred Māori and Pasifika health programmes

3585: 1925:"Research shows navigators effective for Maori health" 516:

at the Healthier Lives Kōrero Tahi symposium, Feb 2024

3117:

Linkage error and linkage bias: a guide for IDI users

137:'s eleven collaborative research programmes known as 3422:

Pasifika Medical Association Group (17 March 2021).

788:

Co-designing Health Research in Aotearoa New Zealand

381:

to detect early relapse and allow timely treatment.

3225:"Earthquakes literally broke hearts in New Zealand" 1841:"Oire Tokoroa Family Diabetes Prevention Programme" 1797:

Australian and New Zealand Journal of Public Health

642: 597: 452: 402: 112: 102: 89: 77: 61: 53: 45: 37: 2796:Ewens, Ella; Young, Leanne; Mackay, Sally (2023). 1152:"An international lens on Healthier Lives science" 1082:"Healthier Lives Challenge tackles major diseases" 1430:. Wellington: Te Whatu Ora - Health New Zealand. 812:Healthier Lives – He Oranga Hauora. (June 2019). 3500:Amohia Boulton; Debbie Goodwin (February 2024). 191:Ministry of Business, Innovation, and Employment 762:The Economic and Social Cost of Type 2 Diabetes 742:The Economic and Social Cost of Type 2 Diabetes 777:Pathways between research, policy and practice 464:Community-led research for sustainable futures 3120:. Wellington: University of Otago Wellington. 442:Research led by Nina Scott, John Oetzel, and 8: 1956:International Journal of Qualitative Methods 1027:"Tackling The Inequities In Health Outcomes" 744:report to the New Zealand Parliament in 2021 2606:Journal of the Royal Society of New Zealand 1056:"Magnitude of health challenge highlighted" 3571:He Pikinga Waiora Implementation Framework 2347:International Journal for Equity in Health 1619:International Journal for Equity in Health 1080:New Zealand Government (4 December 2015). 29: 18: 3559:Healthier Lives publications archived at 3200: 3114:Kvalsvig, A.; Gibb, S.; Teng, A. (2019). 3090: 3035: 2986: 2831: 2813: 2764: 2723: 2682: 2617: 2576: 2502: 2417: 2376: 2358: 2316: 2259: 2241: 2199: 2181: 2132: 2082: 1967: 1899: 1816: 1766: 1724: 1706: 1640: 1630: 1589: 1571: 1486: 1468: 1296: 949:"Further boost for Otago health sciences" 716:Several studies led by Andrea Teng used 3256:Diabetes Research and Clinical Practice 3162:University of Otago Research Highlights 2946:Banwell, Karen; Kingham, Simon (2023). 913: 3566:Healthier Lives Implementation Network 667:Healthy physical activity environments 639: 594: 449: 399: 251:Malaghan Institute of Medical Research 2463:. Geneva: World Health Organization. 2170:Implementation Science Communications 1366: 1364: 353:developed sensitive ctDNA assays for 7: 1132: 1130: 1128: 1049: 1047: 613:, an illustration by Yasmine El Orfi 584:in one's diet to reduce the risk of 1025:Heart Foundation (31 August 2019). 947:Elder, Vaughan (24 November 2015). 863:; A Better Start (September 2023), 689:Canterbury earthquakes of 2010–2011 548:Healthy foods and physical activity 3586:Virtual Health Information Network 3344:Bezzant, Niki (24 February 2019). 2856:"HYPE (Healthy Policy Evaluation)" 1403:. Wellington: Ministry of Health. 1054:Elder, Vaughan (5 December 2015). 750:Focus on Fibre and Food Monitoring 131:Healthier Lives – He Oranga Hauora 23:Healthier Lives – He Oranga Hauora 14: 3016:Journal of Transport & Health 2113:Translational Behavioral Medicine 1923:Waatea News (20 September 2020). 1269:Molecular Diagnosis & Therapy 271:Victoria University of Wellington 243:Auckland University of Technology 3448:Witton, Bridie (15 March 2021). 3401:Healthier Lives–He Oranga Hauora 1991:Bhatia, Ripu (7 December 2017). 1929:Waatea News: Māori Radio Station 661: 648: 603: 458: 408: 3561:University of Otago OUR Archive 3370:Murphy, Sally (16 March 2021). 3311:The New Zealand Medical Journal 2023:Heart (British Cardiac Society) 1371:Dreaver, Charlie (5 May 2018). 2881:Kingham, Simon (24 May 2022). 221:University of Otago Professor 1: 3268:10.1016/j.diabres.2018.12.003 3202:10.1016/S2542-5196(17)30101-8 2988:10.1080/1177083X.2023.2180762 2925:10.1080/17450101.2023.2289441 2619:10.1080/03036758.2022.2137532 2419:10.1016/s0140-6736(18)31809-9 1768:10.1080/1177083X.2021.1876743 1339:10.1016/S0140-6736(18)30664-0 1060:Otago Daily Times Online News 953:Otago Daily Times Online News 833:10.17608/k6.auckland.19372769 2667:10.1016/j.eclinm.2022.101774 2035:10.1136/heartjnl-2023-322795 805:Co-designing health research 169:Establishment and governance 3606:Medical research in Oceania 3601:National Science Challenges 3474:Mann, Jim (15 March 2023). 3189:The Lancet Planetary Health 3158:"Big data for big problems" 2712:New Zealand Medical Journal 2301:10.1136/bmjopen-2022-065721 1884:10.1136/bmjopen-2017-019572 1524:10.1007/978-1-0716-2140-0_2 1397:Ministry of Health (2018). 187:National Science Challenges 139:National Science Challenges 3622: 2504:10.1007/s00125-023-05894-8 2360:10.1186/s12939-023-02087-y 2243:10.1186/s13012-023-01304-0 2183:10.1186/s43058-022-00373-4 1632:10.1186/s12939-020-01222-3 1470:10.1186/s13148-024-01659-1 1281:10.1007/s40291-023-00651-4 610:Sustainable dietary intake 544:screening intervention. 3037:10.1016/j.jth.2024.101809 2753:Nutrition & Dietetics 1969:10.1177/16094069231176348 1573:10.1186/s12992-017-0295-8 660: 654:Healthy food environments 647: 602: 457: 444:Bridgette Masters-Awatere 407: 28: 21: 2084:10.1177/1177180117753169 1560:Globalization and Health 807:, Te Papa, February 2024 426:: reversible changes to 263:University of Canterbury 233:on 4 December 2015. The 3551:Healthier Lives website 2766:10.1111/1747-0080.12844 1809:10.1111/1753-6405.13187 211:Health Research Council 2230:Implementation Science 1233:10.1093/carcin/bgaa102 808: 745: 700:Statistics New Zealand 677:District Health Boards 586:coronary heart disease 580:, and slowly-digested 517: 379:neuroendocrine cancers 349:). Parry Guilford and 342: 299:cardiovascular disease 259:University of Auckland 201: 182: 147:cardiovascular disease 802: 739: 625:planetary health diet 508: 340: 285:was appointed Chair. 267:University of Waikato 199: 176: 3581:Manawataki Fatu Fatu 1457:Clinical Epigenetics 1333:(10133): 1897–1907. 578:monounsaturated fats 574:polyunsaturated fats 3231:. 26 September 2017 3092:10.32866/001c.92735 3028:2024JTHea..3601809R 2578:10.3390/su142113900 1962:: 160940692311763. 1669:journal.nzma.org.nz 1031:Heart Foundation NZ 926:New Zealand Gazette 874:University of Otago 709:, a major cause of 695:Big and linked data 512:, Magda Rosin, and 235:University of Otago 3428:New Zealand Doctor 3138:. 22 November 2020 3058:. 21 February 2024 2862:. 16 November 2020 2815:10.3390/nu15224797 2725:10.26635/6965.5698 2412:(10170): 434–445. 2125:10.1093/tbm/iby093 1708:10.3390/nu16121853 809: 746: 706:Heliobacter pylori 629:Our Land and Water 518: 391:Ministry of Health 343: 333:Precision medicine 215:Ministry of Health 202: 183: 57:Research programme 3525:978-0-473-63852-8 3164:. 31 January 2018 2952:Built Environment 2655:eClinicalMedicine 2470:978-92-4-006166-8 1533:978-1-0716-2139-4 1437:978-1-98-856877-5 1410:978-1-98-853933-1 1227:(11): 1507–1517. 980:. 9 February 2017 928:. 31 January 2014 901:978-0-473-63852-8 850:978-0-473-64187-0 673: 672: 621:Cristina Cleghorn 617: 616: 522:Clíona Ní Mhurchú 514:Cristina Cleghorn 510:Clíona Ní Mhurchú 470: 469: 420: 419: 355:colorectal cancer 255:Massey University 128: 127: 3613: 3538: 3537: 3497: 3491: 3490: 3488: 3486: 3480:The Conversation 3471: 3465: 3464: 3462: 3460: 3445: 3439: 3438: 3436: 3434: 3419: 3413: 3412: 3410: 3408: 3393: 3387: 3386: 3384: 3382: 3367: 3361: 3360: 3358: 3356: 3341: 3335: 3334: 3302: 3296: 3295: 3247: 3241: 3240: 3238: 3236: 3221: 3215: 3214: 3204: 3195:(6): E242–E253. 3180: 3174: 3173: 3171: 3169: 3154: 3148: 3147: 3145: 3143: 3128: 3122: 3121: 3111: 3105: 3104: 3094: 3074: 3068: 3067: 3065: 3063: 3048: 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570:saturated fats 558:refined grains 556:and replacing 549: 546: 533:primary health 491:Matire Harwood 468: 467: 455: 454: 439: 436: 418: 417: 405: 404: 334: 331: 290: 287: 204:In April 2015 170: 167: 126: 125: 118:healthierlives 114: 110: 109: 104: 100: 99: 93: 90: 87: 86: 81: 78: 75: 74: 72: 71: 65: 63: 59: 58: 55: 51: 50: 47: 43: 42: 39: 35: 34: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 3618: 3607: 3604: 3602: 3599: 3598: 3596: 3587: 3584: 3582: 3579: 3577: 3574: 3572: 3569: 3567: 3564: 3562: 3558: 3556: 3552: 3549: 3548: 3544: 3535: 3531: 3527: 3521: 3517: 3513: 3509: 3505: 3504: 3496: 3493: 3481: 3477: 3470: 3467: 3455: 3451: 3444: 3441: 3429: 3425: 3418: 3415: 3402: 3398: 3392: 3389: 3377: 3373: 3366: 3363: 3351: 3347: 3340: 3337: 3332: 3328: 3324: 3320: 3316: 3312: 3308: 3301: 3298: 3293: 3289: 3285: 3281: 3277: 3273: 3269: 3265: 3261: 3257: 3253: 3246: 3243: 3230: 3226: 3220: 3217: 3212: 3208: 3203: 3198: 3194: 3190: 3186: 3179: 3176: 3163: 3159: 3153: 3150: 3137: 3133: 3127: 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