Knowledge (XXG)

Helen S. Mayberg

Source đź“ť

263:
25 is connected to parts of the brain that are related to observable depression traits, such as appetite and sleeping habits. Her hypothesis is sometimes described as a pacemaker for the brain: electronic pulses that correct both the cause and the symptoms of depression. Current research looks into why some patients respond to DBS and others do not. To this end, a study led by Dr. Mayberg showed that brief intraoperative exposure to therapeutic stimulation at the time of implantation surgery induces rapid and consistent electrophysiological brain state change—indexed by a decrease in
932:
Ruben Gur, director of neuropsychology at the University of Pennsylvania School of Medicine, told jurors Tuesday that former Pfc. Steven Dale Green would be prone to acting inappropriately in chaotic situations because of the brain damage. Gur, testifying for the defense, said the brain damage likely
376:
One issue surrounding DBS is that it stands to change a patient’s identity or cause other undesirable emotional or biological conditions. The rebuttal is that severely depressed individuals often have lost a sense of self and that invasive procedures can block the barrier that might be the root cause
200:
Mayberg's research in neurology came about through observations that the psychological diagnoses of mental disorders was not aided by, or backed up by, neurological evidence—and that developing a system of mapping the circuitry of brain activity would allow for more objective diagnoses and treatment.
262:
of the brain in severely depressed patients. Initial results were encouraging, though clinical trials were deemed futile and ultimately halted; however, there were positive changes in the success rate of the trial after the trial was halted. As a result, she resumed research on her hypothesis. Area
368:
practicing meditation, and experiments involving DBS, it was likely that meditation could improve brain waves that are important to mental health — yet when a patient experiences a certain degree of depression, it takes biological treatment to restore the patient to where they can meditate at all.
267:
measured at the site of stimulation. These intraoperative brain state changes are seen in individual subjects and are correlated with a significant and sustained reduction in depressive symptoms outside of the operating room without additional stimulation, establishing reduction in beta power as a
413:
Other scholars, including Mayberg, have argued in editorials and interviews that science of the brain cannot be used, at least at this point, to offer evidence for a conviction. By extension, it could be erroneously interpreted that brain analyses could predict a person’s potential for criminal
367:
on the brain. The Dalai Lama was interested in whether the brain impacts the mind or if it might be the other way around. Mayberg pointed out the impact of DBS on severely depressed individuals. Their informal hypothesis was that, based on experiments that examined brain behavior from people
388:. Her commentary focused on how severely depressed patients are rarely irrational, and that there needs to be open communication and a two-way understanding of expectations. She also asserted in publications that DBS patients should have their own words reflected in the medical literature. 157:. As of August 2019, she has published 211 original peer-reviewed articles, 31 books and book chapters, and acted as principal investigator on 24 research grants. Mayberg is coinventor with Andres Lozano of “Method for Treating Depression Mood Disorders and Anxiety Disorders using 540:
Mayberg, HS; Liotti, M; Brannan, SK; McGinnis, S; Mahurin, RK; Jerabek, PA; Silva, JA; Tekell, JL; Martin, CC; Lancaster, JL; Fox, PT (1999). "Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness".
1086:
Holtzheimer, P. E.; Kelley, M. E.; Gross, R. E.; Filkowski, M. M.; Garlow, S. J.; Barrocas, A.; Wint, D.; Craighead, M. C.; Kozarsky, J.; Chismar, R.; Moreines, J. L.; Mewes, K.; Posse, P. R.; Gutman, D. A.; Mayberg, H. S. (January 2, 2012).
403:, is based on the concept that MRI and PET scans as well as other means of examining of a person’s brain composition, can be used to hold harmless an alleged perpetrator in a court of law. Or, conversely, to justify a conviction. 857:
Thomas, M; Sing, H; Belenky, G; et al. (December 2000). "Neural basis of alertness and cognitive performance impairments during sleepiness. I. Effects of 24 h of sleep deprivation on waking human regional brain activity".
779:
Mayberg, HS; Brannan, SK; Mahurin, RK; Jerabek, PA; Brickman, JS; Tekell, JL; Silva, JA; McGinnis, S; Glass, TG; Martin, CC; Fox, PT (1997). "Cingulate function in depression: a potential predictor of treatment response".
818:
Mayberg, HS; Brannan, SK; Tekell, JL; Silva, JA; Mahurin, RK; McGinnis, S; Jerabek, PA (2000). "Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response".
1634:
Sendi, Mohammad S. E; Waters, Allison C; Tiruvadi, Vineet; Riva-Pose, Patricio; Crowell, Andrea; Isbaine, Faical; Gale, John.T; Choi, Ki Sueng; Gross, Robert. E; Mayberg, Helen. S; Mahmoudi, Babak (2021-11-03).
1777: 524: 381: 82: 2320: 236:
that discriminate patient subgroups and optimize treatment selection in the management of individual patients across all stages of illness. She also concentrates on testing
1878: 2315: 1738: 984:"Considering Eligibility for Studies of Deep Brain Stimulation for Treatment-Resistant Depression Insights From a Clinical Trial in Unipolar and Bipolar Depression" 2258: 1562:"St. Jude Medical, BROADEN depression clinical trial failure, futility analysis, Helen Mayberg, deep brain stimulation (DBS) of Cg25, Parkinson's disease, FDA" 1164: 1266: 452: 1752: 2325: 745:"Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment" 2305: 2263: 189: 181: 512: 64: 2300: 456: 2128: 1298: 436: 1685: 180:. As of 2018, Mayberg holds positions as Professor of Neurology and Neurosurgery and Professor, Psychiatry and Neuroscience, both at 2310: 960: 448: 428: 523:(2016), the Gold Medal Award, Society of Biological Psychiatry (2014), Joan and Stanford Alexander Award in Psychiatry (2013), the 1609: 2007: 88: 70: 1212: 407:
was among those who postulated this theory in the 1980s, and it gained attention in the press after the trial and conviction of
468: 1854: 2295: 154: 76: 516: 460: 1347: 488: 213: 665:"Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy" 476: 946: 2031: 244:, engineers, imaging scientists and clinicians to refine, optimize and extend the treatment of depression and other 480: 258:
One deep brain stimulation treatment for depression, developed by Mayberg and colleagues, placed electrodes in the
165: 2055: 1274: 484: 185: 142: 1756: 1213:"William & Pudge Landau Lectureship | Office of Neuroscience Research | Washington University in St. Louis" 500: 444: 2129:"National Academy of Inventors Elects Lollar, Mayberg as Fellows > Publications > Hemophilia of Georgia" 1299:"National Academy of Inventors Elects Lollar, Mayberg as Fellows > Publications > Hemophilia of Georgia" 311:
Psychophysiological Assessment of DBS Effects in TRD Phase  II, Hope for Depression Research Foundation
162: 146: 1975: 2290: 252: 237: 221: 150: 1714: 432: 169: 2192: 2172: 2152: 1089:"Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Unipolar and Bipolar Depression" 188:. Since 2018, she has served as Director, Nash Family Center for Advanced Circuit Therapeutics at the 1507: 1380: 592: 241: 1239: 174:
Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Unipolar and Bipolar Depression
2234: 1561: 1267:"The 2010 Roche – Nature Medicine Translational Neuroscience Symposium : Spoonful of Medicine" 1470: 1240:"NARSAD presents 2007 prizes for outstanding achievement in neuroscience and psychiatric research" 701:"Attending to the present: mindfulness meditation reveals distinct neural modes of self-reference" 153:(DBS), a reversible method of selective modulation of a specific brain circuit, for patients with 2104: 883: 844: 805: 566: 508: 2275: 1893: 1830:"Transcript, Meeting 18, Session 3 | Presidential Commission for the Study of Bioethical Issues" 1446: 519:, elected member (2016), V. Sagar Sethi Mental Health Research Award, Psychiatric Foundation of 1829: 1188: 322:
Predictors of Antidepressant Treatment Response: The Emory CIDAR, NIMH  - P50 MH077083-01
1983: 1956: 1948: 1901: 1872: 1732: 1666: 1637:"Intraoperative neural signals predict rapid antidepressant effects of deep brain stimulation" 1543: 1525: 1404: 1396: 1118: 1068: 1013: 956: 920: 875: 836: 797: 766: 730: 686: 650: 620: 558: 472: 408: 205: 177: 333:
Multimodal Assessment of DBS Effects in TRD Phase I, Hope for Depression Research Foundation
2269: 1938: 1656: 1648: 1533: 1515: 1388: 1108: 1100: 1058: 1050: 1003: 995: 867: 828: 789: 756: 720: 712: 676: 642: 610: 600: 550: 400: 300:
Emory-MSSM-GSK-NIMH Collaborative Mood-Anxiety Disorders Initiative, NIMH - U19 MH069056-09
259: 225: 983: 948:
The Brain Defense: Murder in Manhattan and the Dawn of Neuroscience in America's Courtrooms
356: 245: 158: 1778:"When It Comes to Issues of Identity and Authenticity in DBS, Let Patients Have a Voice" 1511: 1384: 1104: 596: 173: 1661: 1636: 1585: 1538: 1495: 1113: 1088: 1063: 1038: 1008: 725: 700: 615: 580: 520: 229: 2173:"Society of Biological Psychiatry Gold Medal Award | Society of Biological Psychiatry" 1136: 832: 663:
Goldapple, K; Segal, Z; Garson, C; Lau, M; Bieling, P; Kennedy, S; Mayberg, H (2004).
2284: 952: 871: 793: 699:
Farb, NA; Segal, ZV; Mayberg, H; Bean, J; McKeon, D; Fatima, Z; Anderson, AK (2007).
633:
Mayberg, HS (1997). "Limbic-cortical dysregulation: a proposed model of depression".
217: 52: 887: 809: 570: 251:
Since the 1990s, electric stimulation of parts of the brain have been used to treat
1496:"Core Concept: Can deep brain stimulation find success beyond Parkinson's disease?" 1471:"Biography of Helen Mayberg | Game Changers | School of Medicine, Emory University" 1054: 507:
Award for Distinguished Service to the Field of Neuroethics (2018), elected to the
504: 404: 209: 848: 1392: 999: 1422: 385: 134: 1804: 1652: 464: 364: 130: 33: 1987: 1952: 1905: 1529: 1400: 681: 664: 1520: 605: 269: 264: 233: 2080: 1960: 1686:"Buddhists Meet Mind Scientists in Conference on Meditation and Depression" 1670: 1547: 1408: 1122: 1072: 1017: 879: 840: 770: 761: 744: 734: 690: 624: 562: 1323: 910: 801: 716: 654: 554: 915: 396: 646: 982:
Filkowski, Megan M.; Mayberg, Helen; Holtzheimer, Paul E. (June 2016).
1165:"Why a 'Lifesaving' Depression Treatment Didn't Pass Clinical Trials" 535:
Partial list of original peer-reviewed articles ranked by citations:
440: 2056:"Two Emory faculty elected to American Academy of Arts and Sciences" 1943: 1926: 137:. Mayberg is known in particular for her work delineating abnormal 360: 138: 384:, where she expressed her clinical and experiential lessons in 1371:
Underwood, Emily (2013-11-01). "Short-Circuiting Depression".
525:
Robert J. and Claire Pasarow Foundation Medical Research Award
1894:"Neuroscience - Law - The Brain on the Stand - Jeffrey Rosen" 1039:"Deep Brain Stimulation for Treatment-Resistant Depression" 911:"Witness: Ex-soldier suffered from impulse control issues" 579:
Biswal, BB; Mennes, M; Zuo, XN; et al. (March 2010).
382:
Presidential Commission for the Study of Bioethical Issues
1614:
IEEE Spectrum: Technology, Engineering, and Science News
2008:"Criminologist Believes Violent Behavior Is Biological" 363:
attended a conference on mindfulness and the impact of
73:(Graduate studies: Department of Radiological Sciences) 240:
for treatment resistant depression, bringing together
83:
Columbia University College of Physicians and Surgeons
116:
Psychiatry, Behavioral sciences, Neurology, Radiology
91:(Research Fellow, Department of Radiology, 1985-1987) 77:
University of Southern California, School of Medicine
2276:
Nash Family Center for Advanced Circuit Therapeutics
1855:"Is "Neurolaw" Coming Soon to a Courtroom Near You?" 2153:"Society of Biological Psychiatry Gold Medal Award" 2081:"V. Sagar Sethi, M.D. Mental Health Research Award" 112: 104: 58: 48: 40: 28: 21: 1348:"Using Deep Brain Stimulation to Treat Depression" 581:"Toward discovery science of human brain function" 427:Mayberg is a member of the Governing Board of the 228:metrics to define brain mechanisms and testing of 184:, and Professor of Psychiatry, Emory University; 499:A list of honors and awards include election to 443:Scientific Advisory Board. She is active in the 232:treatments. She develops imaging biomarkers and 1500:Proceedings of the National Academy of Sciences 255:. The origins of DBS date back to the 1930s. 149:. This work led to the first pilot study of 8: 1877:: CS1 maint: multiple names: authors list ( 2321:Members of the National Academy of Medicine 1737:: CS1 maint: numeric names: authors list ( 1037:Holtzheimer PE III; Mayberg, H. S. (2010). 453:American College of Neuropsychopharmacology 380:Mayberg gave a presentation in 2014 at the 377:of the loss of self, thereby restoring it. 2229: 2227: 2225: 2223: 2221: 2219: 2217: 2215: 2213: 18: 1942: 1660: 1537: 1519: 1112: 1062: 1007: 760: 724: 680: 614: 604: 284:Grants, Contracts and Foundation Sources 1450:Brain & Behavior Research Foundation 1137:"Helen Mayberg | Mount Sinai - New York" 459:, and serves on the editorial boards of 282: 2266:New York Times Magazine (April 6, 2006) 1684:Charles L. Raison, M. D. (2008-03-01). 1427:American Academy of Arts & Sciences 902: 503:Society of Scholars (2018), recipient, 2316:21st-century American women physicians 2036:Hope For Depression Research Institute 1870: 1730: 2193:"Helen Mayberg Wins Psychiatry Award" 1799: 1797: 1293: 1291: 1261: 1259: 1234: 1232: 513:American Academy of Arts and Sciences 108:Researcher, Professor, Medical Doctor 65:University of California, Los Angeles 7: 1753:"How meditating may help your brain" 1158: 1156: 933:was caused by several head injuries. 457:Organization for Human Brain Mapping 447:, Society of Biological Psychiatry, 1715:"How Thinking Can Change the Brain" 1713:Lama, The 14th Dalai (2019-12-10). 1105:10.1001/archgenpsychiatry.2011.1456 1043:The American Journal of Psychiatry 280:A partial list of recent grants: 14: 2032:"Helen S. Mayberg, M.D Biography" 1692:. Psychiatric Times Vol 25 No 3. 449:American Neurological Association 429:International Neuroethics Society 2326:21st-century American physicians 1189:"Helen Mayberg, M.D. | MindCORE" 872:10.1046/j.1365-2869.2000.00225.x 794:10.1097/00001756-199703030-00048 272:for DBS treatment optimization. 89:Johns Hopkins School of Medicine 71:University of California, Irvine 1925:Hughes, Virginia (2010-03-01). 1853:Magazine, Eryn Brown,Knowable. 1834:bioethicsarchive.georgetown.edu 635:J Neuropsychiatry Clin Neurosci 176:(SCC DBS) for the treatment of 2306:American women neuroscientists 1217:neuroscienceresearch.wustl.edu 1093:Archives of General Psychiatry 1055:10.1176/appi.ajp.2010.10010141 355:In 2017, Mayberg and the 14th 155:treatment-resistant depression 85:New York (Resident, Neurology) 1: 1927:"Science in court: Head case" 1892:Rosen, Jeffrey (2007-03-11). 1494:Shen, Helen H. (2019-03-12). 833:10.1016/s0006-3223(00)01036-2 517:National Academy of Inventors 161:,” US patent 2005/0033379A1. 2109:National Academy of Medicine 1974:Raine, Adrian (2013-04-26). 1393:10.1126/science.342.6158.548 1000:10.1097/YCT.0000000000000281 585:Proc. Natl. Acad. Sci. U.S.A 509:National Academy of Medicine 489:Brain Structure and Function 423:Memberships and associations 214:Positron emission tomography 2301:American women neurologists 1322:Witten, Mark (2004-04-12). 1163:Dobbs, David (2018-04-17). 2342: 1809:www.neuroethicssociety.org 1653:10.1038/s41398-021-01669-0 224:as well as behavioral and 182:Mount Sinai Medical School 141:function in patients with 1586:"Changing Minds: Area 25" 1141:Mount Sinai Health System 351:Meditation and depression 186:Emory University Hospital 120: 97: 67:(B.A. Psychobiology 1976) 2311:American neuroscientists 1641:Translational Psychiatry 1566:www.neurotechreports.com 1447:"Helen S. Mayberg, M.D." 705:Soc Cogn Affect Neurosci 682:10.1001/archpsyc.61.1.34 501:Johns Hopkins University 445:Society for Neuroscience 190:Icahn School of Medicine 1521:10.1073/pnas.1900442116 606:10.1073/pnas.0911855107 487:(associate editor) and 336:Principal Investigator 325:Principal Investigator 314:Principal Investigator 303:Principal Investigator 147:functional neuroimaging 1193:mindcore.sas.upenn.edu 238:deep brain stimulation 151:deep brain stimulation 2296:American neurologists 2264:"A Depression Switch" 2133:Hemophilia of Georgia 555:10.1176/ajp.156.5.675 469:Biological Psychiatry 433:Institute of Medicine 418:Membership and awards 242:electro physiologists 170:intellectual property 2085:www.ncpsychiatry.org 1759:on November 23, 2011 945:Kevin Davis (2017). 762:10.1093/bmb/65.1.193 743:Mayberg, HS (2003). 527:(2013), and others. 463:(associate editor), 16:American neurologist 1980:Wall Street Journal 1976:"The Criminal Mind" 1859:Scientific American 1719:The 14th Dalai Lama 1512:2019PNAS..116.4764S 1385:2013Sci...342..548U 1324:"Mapping the Blues" 717:10.1093/scan/nsm030 669:Arch Gen Psychiatry 647:10.1176/jnp.9.3.471 597:2010PNAS..107.4734B 461:Human Brain Mapping 295:Direct Costs (USD) 285: 226:psychophysiological 216:(PET), sMRI, fMRI, 212:strategies such as 2105:"Helen S. Mayberg" 1898:The New York Times 1610:"Full Page Reload" 1423:"Helen S. Mayberg" 346:Related activities 283: 133:), is an American 2060:Emory News Center 1937:(7287): 340–342. 1690:Psychiatric Times 1506:(11): 4764–4766. 1379:(6158): 548–551. 1352:Discover Magazine 1049:(12): 1437–1444. 921:Paducah, Kentucky 495:Honors and awards 477:Brain Stimulation 409:John Hinckley Jr. 343: 342: 260:Broadmann area 25 178:severe depression 124: 123: 23:Helen S. Mayberg. 2333: 2246: 2245: 2243: 2241: 2235:"Google Scholar" 2231: 2208: 2207: 2205: 2204: 2189: 2183: 2182: 2180: 2179: 2169: 2163: 2162: 2160: 2159: 2149: 2143: 2142: 2140: 2139: 2125: 2119: 2118: 2116: 2115: 2101: 2095: 2094: 2092: 2091: 2077: 2071: 2070: 2068: 2067: 2062:. April 11, 2017 2052: 2046: 2045: 2043: 2042: 2028: 2022: 2021: 2019: 2018: 2004: 1998: 1997: 1995: 1994: 1971: 1965: 1964: 1946: 1922: 1916: 1915: 1913: 1912: 1889: 1883: 1882: 1876: 1868: 1866: 1865: 1850: 1844: 1843: 1841: 1840: 1826: 1820: 1819: 1817: 1815: 1801: 1792: 1791: 1789: 1788: 1774: 1768: 1767: 1765: 1764: 1755:. Archived from 1749: 1743: 1742: 1736: 1728: 1726: 1725: 1710: 1704: 1703: 1701: 1700: 1681: 1675: 1674: 1664: 1631: 1625: 1624: 1622: 1621: 1606: 1600: 1599: 1597: 1596: 1582: 1576: 1575: 1573: 1572: 1558: 1552: 1551: 1541: 1523: 1491: 1485: 1484: 1482: 1481: 1467: 1461: 1460: 1458: 1457: 1443: 1437: 1436: 1434: 1433: 1419: 1413: 1412: 1368: 1362: 1361: 1359: 1358: 1344: 1338: 1337: 1335: 1334: 1319: 1313: 1312: 1310: 1309: 1295: 1286: 1285: 1283: 1282: 1273:. Archived from 1271:blogs.nature.com 1263: 1254: 1253: 1251: 1250: 1236: 1227: 1226: 1224: 1223: 1209: 1203: 1202: 1200: 1199: 1185: 1179: 1178: 1176: 1175: 1160: 1151: 1150: 1148: 1147: 1133: 1127: 1126: 1116: 1083: 1077: 1076: 1066: 1034: 1028: 1027: 1025: 1024: 1011: 979: 973: 972: 970: 969: 942: 936: 935: 929: 928: 907: 891: 852: 813: 774: 764: 738: 728: 694: 684: 658: 628: 618: 608: 574: 481:Neuroinformatics 401:Neurocriminology 286: 246:neuropsychiatric 204:Mayberg studies 192:at Mount Sinai. 163:St. Jude Medical 143:major depression 127:Helen S. Mayberg 19: 2341: 2340: 2336: 2335: 2334: 2332: 2331: 2330: 2281: 2280: 2255: 2250: 2249: 2239: 2237: 2233: 2232: 2211: 2202: 2200: 2197:Dana Foundation 2191: 2190: 2186: 2177: 2175: 2171: 2170: 2166: 2157: 2155: 2151: 2150: 2146: 2137: 2135: 2127: 2126: 2122: 2113: 2111: 2103: 2102: 2098: 2089: 2087: 2079: 2078: 2074: 2065: 2063: 2054: 2053: 2049: 2040: 2038: 2030: 2029: 2025: 2016: 2014: 2006: 2005: 2001: 1992: 1990: 1973: 1972: 1968: 1944:10.1038/464340a 1924: 1923: 1919: 1910: 1908: 1891: 1890: 1886: 1869: 1863: 1861: 1852: 1851: 1847: 1838: 1836: 1828: 1827: 1823: 1813: 1811: 1803: 1802: 1795: 1786: 1784: 1776: 1775: 1771: 1762: 1760: 1751: 1750: 1746: 1729: 1723: 1721: 1712: 1711: 1707: 1698: 1696: 1683: 1682: 1678: 1633: 1632: 1628: 1619: 1617: 1616:. 18 April 2017 1608: 1607: 1603: 1594: 1592: 1590:www.cbsnews.com 1584: 1583: 1579: 1570: 1568: 1560: 1559: 1555: 1493: 1492: 1488: 1479: 1477: 1469: 1468: 1464: 1455: 1453: 1445: 1444: 1440: 1431: 1429: 1421: 1420: 1416: 1370: 1369: 1365: 1356: 1354: 1346: 1345: 1341: 1332: 1330: 1321: 1320: 1316: 1307: 1305: 1297: 1296: 1289: 1280: 1278: 1265: 1264: 1257: 1248: 1246: 1238: 1237: 1230: 1221: 1219: 1211: 1210: 1206: 1197: 1195: 1187: 1186: 1182: 1173: 1171: 1162: 1161: 1154: 1145: 1143: 1135: 1134: 1130: 1085: 1084: 1080: 1036: 1035: 1031: 1022: 1020: 981: 980: 976: 967: 965: 963: 944: 943: 939: 926: 924: 909: 908: 904: 899: 856: 821:Biol Psychiatry 817: 814:Citations: 1127 778: 775:Citations: 1156 742: 739:Citations: 1163 698: 695:Citations: 1321 662: 659:Citations: 1507 632: 629:Citations: 2100 578: 575:Citations: 2557 543:Am J Psychiatry 539: 533: 505:Steven E. Hyman 497: 485:Neuromodulation 425: 420: 394: 374: 353: 348: 278: 208:and integrates 198: 166:Neuromodulation 159:Neuromodulation 36: 24: 17: 12: 11: 5: 2339: 2337: 2329: 2328: 2323: 2318: 2313: 2308: 2303: 2298: 2293: 2283: 2282: 2279: 2278: 2273: 2267: 2261: 2254: 2253:External links 2251: 2248: 2247: 2209: 2184: 2164: 2144: 2120: 2096: 2072: 2047: 2023: 1999: 1966: 1917: 1884: 1845: 1821: 1793: 1769: 1744: 1705: 1676: 1626: 1601: 1577: 1553: 1486: 1462: 1438: 1414: 1363: 1339: 1314: 1287: 1255: 1228: 1204: 1180: 1152: 1128: 1099:(2): 150–158. 1078: 1029: 994:(2): 122–126. 988:Journal of ECT 974: 961: 937: 901: 900: 898: 895: 894: 893: 892:Citations: 961 854: 853:Citations: 961 815: 788:(4): 1057–61. 776: 740: 696: 660: 630: 591:(10): 4734–9. 576: 532: 529: 521:North Carolina 496: 493: 424: 421: 419: 416: 393: 390: 373: 370: 352: 349: 347: 344: 341: 340: 337: 334: 330: 329: 326: 323: 319: 318: 315: 312: 308: 307: 304: 301: 297: 296: 293: 290: 289:Title and No. 277: 274: 230:antidepressant 197: 194: 129:(born 1956 in 122: 121: 118: 117: 114: 110: 109: 106: 102: 101: 99:Medical career 95: 94: 93: 92: 86: 80: 74: 68: 60: 56: 55: 50: 46: 45: 42: 38: 37: 32: 30: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 2338: 2327: 2324: 2322: 2319: 2317: 2314: 2312: 2309: 2307: 2304: 2302: 2299: 2297: 2294: 2292: 2291:Living people 2289: 2288: 2286: 2277: 2274: 2271: 2270:Helen Mayberg 2268: 2265: 2262: 2260: 2257: 2256: 2252: 2236: 2230: 2228: 2226: 2224: 2222: 2220: 2218: 2216: 2214: 2210: 2198: 2194: 2188: 2185: 2174: 2168: 2165: 2154: 2148: 2145: 2134: 2130: 2124: 2121: 2110: 2106: 2100: 2097: 2086: 2082: 2076: 2073: 2061: 2057: 2051: 2048: 2037: 2033: 2027: 2024: 2013: 2009: 2003: 2000: 1989: 1985: 1981: 1977: 1970: 1967: 1962: 1958: 1954: 1950: 1945: 1940: 1936: 1932: 1928: 1921: 1918: 1907: 1903: 1899: 1895: 1888: 1885: 1880: 1874: 1860: 1856: 1849: 1846: 1835: 1831: 1825: 1822: 1810: 1806: 1800: 1798: 1794: 1783: 1779: 1773: 1770: 1758: 1754: 1748: 1745: 1740: 1734: 1720: 1716: 1709: 1706: 1695: 1691: 1687: 1680: 1677: 1672: 1668: 1663: 1658: 1654: 1650: 1646: 1642: 1638: 1630: 1627: 1615: 1611: 1605: 1602: 1591: 1587: 1581: 1578: 1567: 1563: 1557: 1554: 1549: 1545: 1540: 1535: 1531: 1527: 1522: 1517: 1513: 1509: 1505: 1501: 1497: 1490: 1487: 1476: 1475:med.emory.edu 1472: 1466: 1463: 1451: 1448: 1442: 1439: 1428: 1424: 1418: 1415: 1410: 1406: 1402: 1398: 1394: 1390: 1386: 1382: 1378: 1374: 1367: 1364: 1353: 1349: 1343: 1340: 1329: 1325: 1318: 1315: 1304: 1300: 1294: 1292: 1288: 1277:on 2019-12-10 1276: 1272: 1268: 1262: 1260: 1256: 1245: 1241: 1235: 1233: 1229: 1218: 1214: 1208: 1205: 1194: 1190: 1184: 1181: 1170: 1166: 1159: 1157: 1153: 1142: 1138: 1132: 1129: 1124: 1120: 1115: 1110: 1106: 1102: 1098: 1094: 1090: 1082: 1079: 1074: 1070: 1065: 1060: 1056: 1052: 1048: 1044: 1040: 1033: 1030: 1019: 1015: 1010: 1005: 1001: 997: 993: 989: 985: 978: 975: 964: 962:9780698183353 958: 954: 950: 949: 941: 938: 934: 922: 918: 917: 912: 906: 903: 896: 889: 885: 881: 877: 873: 869: 866:(4): 335–52. 865: 861: 855: 850: 846: 842: 838: 834: 830: 827:(8): 830–43. 826: 822: 816: 811: 807: 803: 799: 795: 791: 787: 783: 777: 772: 768: 763: 758: 754: 750: 746: 741: 736: 732: 727: 722: 718: 714: 711:(4): 313–22. 710: 706: 702: 697: 692: 688: 683: 678: 674: 670: 666: 661: 656: 652: 648: 644: 641:(3): 471–81. 640: 636: 631: 626: 622: 617: 612: 607: 602: 598: 594: 590: 586: 582: 577: 572: 568: 564: 560: 556: 552: 549:(5): 675–82. 548: 544: 538: 537: 536: 530: 528: 526: 522: 518: 514: 510: 506: 502: 494: 492: 490: 486: 482: 478: 474: 470: 466: 462: 458: 454: 450: 446: 442: 438: 437:Dana Alliance 434: 430: 422: 417: 415: 411: 410: 406: 402: 399:, related to 398: 391: 389: 387: 383: 378: 371: 369: 366: 362: 358: 350: 345: 338: 335: 332: 331: 327: 324: 321: 320: 316: 313: 310: 309: 306:$ 11,133,630 305: 302: 299: 298: 294: 291: 288: 287: 281: 275: 273: 271: 266: 261: 256: 254: 249: 247: 243: 239: 235: 231: 227: 223: 219: 215: 211: 207: 202: 195: 193: 191: 187: 183: 179: 175: 171: 168:licensed her 167: 164: 160: 156: 152: 148: 144: 140: 136: 132: 128: 119: 115: 111: 107: 103: 100: 96: 90: 87: 84: 81: 78: 75: 72: 69: 66: 63: 62: 61: 57: 54: 53:United States 51: 47: 43: 39: 35: 31: 27: 20: 2238:. Retrieved 2201:. Retrieved 2199:. 2013-04-11 2196: 2187: 2176:. Retrieved 2167: 2156:. Retrieved 2147: 2136:. Retrieved 2132: 2123: 2112:. Retrieved 2108: 2099: 2088:. Retrieved 2084: 2075: 2064:. Retrieved 2059: 2050: 2039:. Retrieved 2035: 2026: 2015:. Retrieved 2011: 2002: 1991:. Retrieved 1979: 1969: 1934: 1930: 1920: 1909:. Retrieved 1897: 1887: 1862:. Retrieved 1858: 1848: 1837:. Retrieved 1833: 1824: 1812:. Retrieved 1808: 1805:"Leadership" 1785:. Retrieved 1781: 1772: 1761:. Retrieved 1757:the original 1747: 1722:. Retrieved 1718: 1708: 1697:. Retrieved 1693: 1689: 1679: 1644: 1640: 1629: 1618:. Retrieved 1613: 1604: 1593:. Retrieved 1589: 1580: 1569:. Retrieved 1565: 1556: 1503: 1499: 1489: 1478:. Retrieved 1474: 1465: 1454:. Retrieved 1452:. 2017-03-14 1449: 1441: 1430:. Retrieved 1426: 1417: 1376: 1372: 1366: 1355:. Retrieved 1351: 1342: 1331:. Retrieved 1327: 1317: 1306:. Retrieved 1302: 1279:. Retrieved 1275:the original 1270: 1247:. Retrieved 1243: 1220:. Retrieved 1216: 1207: 1196:. Retrieved 1192: 1183: 1172:. Retrieved 1169:The Atlantic 1168: 1144:. Retrieved 1140: 1131: 1096: 1092: 1081: 1046: 1042: 1032: 1021:. Retrieved 991: 987: 977: 966:. Retrieved 947: 940: 931: 925:. Retrieved 923:. 2009-05-12 914: 905: 863: 859: 824: 820: 785: 781: 752: 748: 708: 704: 675:(1): 34–41. 672: 668: 638: 634: 588: 584: 546: 542: 534: 531:Publications 498: 467:, Clinical, 426: 412: 405:Adrian Raine 395: 379: 375: 354: 328:$ 7,500,000 279: 257: 250: 210:neuroimaging 203: 199: 126: 125: 98: 2259:DBS Summary 1814:13 February 1782:www.sfn.org 1303:www.hog.org 1244:EurekAlert! 860:J Sleep Res 782:NeuroReport 755:: 193–207. 749:Br Med Bull 515:(2017) and 386:neuroethics 372:Neuroethics 248:disorders. 172:to develop 135:neurologist 79:(M.D. 1981) 49:Citizenship 41:Nationality 2285:Categories 2203:2019-12-10 2178:2019-12-10 2158:2019-08-20 2138:2019-08-20 2114:2020-07-20 2090:2019-08-20 2066:2019-08-19 2041:2019-08-19 2017:2019-12-11 1993:2019-12-11 1911:2019-12-11 1864:2019-12-11 1839:2019-12-11 1787:2019-12-11 1763:2019-12-11 1724:2019-12-11 1699:2019-12-11 1647:(1): 551. 1620:2019-12-10 1595:2019-12-10 1571:2019-12-10 1480:2019-09-13 1456:2019-12-10 1432:2019-12-10 1357:2019-12-10 1333:2019-12-10 1328:The Walrus 1308:2019-12-10 1281:2019-12-10 1249:2019-12-10 1222:2019-09-13 1198:2019-09-13 1174:2019-09-13 1146:2019-09-13 1023:2019-08-16 968:2018-02-12 927:2018-02-12 897:References 473:ex officio 465:NeuroImage 414:behavior. 365:meditation 357:Dalai Lama 339:$ 400,000 317:$ 550,000 253:Parkinsons 234:algorithms 206:depression 131:California 105:Profession 34:California 2240:16 August 1988:0099-9660 1953:1476-4687 1906:0362-4331 1530:0027-8424 1401:0036-8075 475:editor), 270:biomarker 265:Beta wave 59:Education 2272:at Emory 1961:20237536 1873:cite web 1733:cite web 1671:34728599 1548:30862742 1409:24179199 1123:22213770 1073:21131410 1018:26479487 916:NBC News 888:35893889 880:11123521 841:11063978 810:32709385 771:12697626 735:18985137 691:14706942 625:20176931 571:16258492 563:10327898 511:(2008); 439:and the 397:Neurolaw 392:Neurolaw 196:Research 44:American 2012:NPR.org 1662:8563808 1539:6421452 1508:Bibcode 1381:Bibcode 1373:Science 1114:4423545 1064:4413473 1009:4834065 953:Penguin 802:9141092 726:2566754 655:9276848 616:2842060 593:Bibcode 1986:  1959:  1951:  1931:Nature 1904:  1669:  1659:  1546:  1536:  1528:  1407:  1399:  1121:  1111:  1071:  1061:  1016:  1006:  959:  886:  878:  849:634661 847:  839:  808:  800:  769:  733:  723:  689:  653:  623:  613:  569:  561:  455:, the 441:NARSAD 435:, the 431:, the 276:Grants 268:novel 220:, and 145:using 884:S2CID 845:S2CID 806:S2CID 567:S2CID 361:Tibet 292:Role 139:brain 113:Field 2242:2019 1984:ISSN 1957:PMID 1949:ISSN 1902:ISSN 1879:link 1816:2018 1739:link 1667:PMID 1544:PMID 1526:ISSN 1405:PMID 1397:ISSN 1119:PMID 1069:PMID 1014:PMID 957:ISBN 876:PMID 837:PMID 798:PMID 767:PMID 731:PMID 687:PMID 651:PMID 621:PMID 559:PMID 29:Born 1939:doi 1935:464 1657:PMC 1649:doi 1534:PMC 1516:doi 1504:116 1389:doi 1377:342 1109:PMC 1101:doi 1059:PMC 1051:doi 1047:167 1004:PMC 996:doi 868:doi 829:doi 790:doi 757:doi 721:PMC 713:doi 677:doi 643:doi 611:PMC 601:doi 589:107 551:doi 547:156 359:of 222:EEG 218:DTI 2287:: 2212:^ 2195:. 2131:. 2107:. 2083:. 2058:. 2034:. 2010:. 1982:. 1978:. 1955:. 1947:. 1933:. 1929:. 1900:. 1896:. 1875:}} 1871:{{ 1857:. 1832:. 1807:. 1796:^ 1780:. 1735:}} 1731:{{ 1717:. 1694:25 1688:. 1665:. 1655:. 1645:11 1643:. 1639:. 1612:. 1588:. 1564:. 1542:. 1532:. 1524:. 1514:. 1502:. 1498:. 1473:. 1425:. 1403:. 1395:. 1387:. 1375:. 1350:. 1326:. 1301:. 1290:^ 1269:. 1258:^ 1242:. 1231:^ 1215:. 1191:. 1167:. 1155:^ 1139:. 1117:. 1107:. 1097:69 1095:. 1091:. 1067:. 1057:. 1045:. 1041:. 1012:. 1002:. 992:32 990:. 986:. 955:. 951:. 930:. 919:. 913:. 882:. 874:. 862:. 843:. 835:. 825:48 823:. 804:. 796:. 784:. 765:. 753:65 751:. 747:. 729:. 719:. 707:. 703:. 685:. 673:61 671:. 667:. 649:. 637:. 619:. 609:. 599:. 587:. 583:. 565:. 557:. 545:. 491:. 483:, 479:, 451:, 2244:. 2206:. 2181:. 2161:. 2141:. 2117:. 2093:. 2069:. 2044:. 2020:. 1996:. 1963:. 1941:: 1914:. 1881:) 1867:. 1842:. 1818:. 1790:. 1766:. 1741:) 1727:. 1702:. 1673:. 1651:: 1623:. 1598:. 1574:. 1550:. 1518:: 1510:: 1483:. 1459:. 1435:. 1411:. 1391:: 1383:: 1360:. 1336:. 1311:. 1284:. 1252:. 1225:. 1201:. 1177:. 1149:. 1125:. 1103:: 1075:. 1053:: 1026:. 998:: 971:. 890:. 870:: 864:9 851:. 831:: 812:. 792:: 786:8 773:. 759:: 737:. 715:: 709:2 693:. 679:: 657:. 645:: 639:9 627:. 603:: 595:: 573:. 553:: 471:(

Index

California
United States
University of California, Los Angeles
University of California, Irvine
University of Southern California, School of Medicine
Columbia University College of Physicians and Surgeons
Johns Hopkins School of Medicine
California
neurologist
brain
major depression
functional neuroimaging
deep brain stimulation
treatment-resistant depression
Neuromodulation
St. Jude Medical
Neuromodulation
intellectual property
Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Unipolar and Bipolar Depression
severe depression
Mount Sinai Medical School
Emory University Hospital
Icahn School of Medicine
depression
neuroimaging
Positron emission tomography
DTI
EEG
psychophysiological
antidepressant

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

↑