Knowledge (XXG)

Hemeralopia

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39: 417: 402: 1473: 870: 1542: 1468: 2023: 218:. Wherever possible, environmental illumination should be adjusted to comfortable level. Light-filtering lenses appear to help in people reporting 86:(during the day), which are affected by hemeralopia and in turn degrade the daytime optical response. Hence, many patients feel they see better at 482: 1490: 1485: 1310: 1350: 78:(eye discomfort/pain in light), which is typical of inflammations of the eye. Nighttime vision largely remains unchanged due to the use of 1463: 432: 1458: 1345: 912: 1073: 372: 172:(CAR), seen when certain cancers incite the production of deleterious antibodies against retinal components, may cause hemeralopia. 1213: 1178: 1753: 1271: 1183: 128:
has been used to describe night blindness rather than day blindness by many non-English-speaking doctors, causing confusion.
1173: 902: 1266: 1157: 1023: 169: 1664: 1355: 1340: 552: 510: 475: 1480: 1276: 1250: 1208: 1203: 1068: 941: 929: 885: 1547: 946: 1659: 1453: 1300: 1145: 892: 1198: 1169: 793: 758: 443: 179:(aka Pepper syndrome). Cohen syndrome is mostly characterized by obesity, mental retardation and craniofacial 1669: 1423: 1223: 743: 736: 1938: 1908: 1843: 1838: 1565: 843: 708: 468: 1881: 1557: 1654: 1240: 1235: 1193: 1008: 924: 38: 1959: 1833: 1633: 1516: 1508: 1296: 1260: 1245: 1100: 880: 660: 421: 1570: 1320: 1228: 1152: 1105: 917: 853: 838: 698: 647: 1913: 1810: 1575: 1435: 1218: 875: 781: 368: 337: 288: 71: 27: 1701: 1691: 1537: 1512: 1445: 1411: 1330: 961: 951: 848: 703: 590: 580: 327: 319: 278: 270: 234: 184: 64: 1768: 1732: 1696: 1315: 1140: 1127: 1061: 1018: 936: 748: 680: 600: 585: 203: 188: 113: 149: 1998: 1850: 1795: 1638: 1406: 1335: 1117: 1087: 1033: 987: 858: 731: 665: 655: 332: 307: 283: 258: 176: 137: 98: 426: 2017: 1918: 1773: 1713: 1430: 1378: 1325: 1255: 1164: 1051: 1028: 956: 865: 670: 575: 192: 145: 141: 32: 74:
gets worse, characterised by photoaversion (dislike/avoidance of light) rather than
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8q22–23. Rarely, it may have ocular complications such as hemeralopia, pigmentary
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Otherwise, treatment relies on identifying and treating any underlying disorder.
1982: 1933: 1876: 1828: 1806: 1717: 1708: 1628: 1606: 1418: 1390: 1188: 1056: 897: 718: 595: 547: 494: 219: 180: 75: 59:(night blindness), the inability to see clearly in low light. It is also called 1903: 1866: 1790: 1778: 1722: 1683: 1589: 1525: 1504: 1394: 753: 618: 411: 215: 56: 55:
is the inability to see clearly in bright light and is the exact opposite of
1954: 1928: 1802: 1748: 1736: 1621: 1616: 1601: 1597: 1135: 833: 810: 623: 570: 565: 542: 460: 274: 161: 83: 341: 292: 1993: 1758: 1292: 1095: 726: 323: 196: 157: 153: 79: 394: 164:, due to the lens clouding, disperses the light before it can reach the 160:, where the iris is defectively pigmented, may also cause this. Central 1820: 1763: 1305: 1112: 1043: 1013: 1003: 610: 259:"Nyctalopia and hemeralopia: the current usage trend in the literature" 168:
and is a common cause of hemeralopia and photoaversion in the elderly.
1923: 825: 802: 522: 406: 165: 109: 1895: 144:, affecting the cones in the retina, and the anti-epileptic drug 975: 537: 437: 87: 1980: 1376: 779: 508: 464: 121: 117: 136:
Hemeralopia is known to occur in several ocular conditions.
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brain injury. This may also cause concomitant nyctalopia.
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Yet another cause of hemeralopia is uni- or bilateral post
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Another known cause is a rare genetic condition called
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Rehabilitation of visual disorders after brain injury
384: 1947: 1894: 1859: 1819: 1731: 1682: 1647: 1588: 1556: 1524: 1503: 1444: 1389: 1285: 1126: 1086: 1042: 983: 974: 824: 801: 792: 717: 679: 646: 609: 530: 521: 388: 26: 21: 199:, having a serious effect on the person's vision. 1469:arteritic anterior (AAION or arteritic AION) 152:, which fails to constrict in response to light; 476: 8: 1543:Chronic progressive external ophthalmoplegia 871:Thygeson's superficial punctate keratopathy 1977: 1741: 1530: 1521: 1399: 1386: 1373: 980: 798: 789: 776: 527: 518: 505: 483: 469: 461: 385: 37: 18: 331: 282: 214:People with hemeralopia may benefit from 246: 357: 355: 353: 351: 252: 250: 63:. It can be described as insufficient 7: 1351:Familial exudative vitreoretinopathy 156:, which is absence of the iris; and 1474:non-arteritic anterior (NAION) 1311:Leber's hereditary optic neuropathy 1346:Persistent tunica vasculosa lentis 14: 2024:Visual disturbances and blindness 1074:Polypoidal choroidal vasculopathy 367:. East Sussex: Psychology Press. 1179:Central retinal artery occlusion 312:British Journal of Ophthalmology 257:Ohba N, Ohba A (December 2006). 1184:Branch retinal artery occlusion 913:Terrien's marginal degeneration 1214:Bietti's crystalline dystrophy 1174:Central retinal vein occlusion 903:Pellucid marginal degeneration 1: 1267:Vitelliform macular dystrophy 1158:Posterior vitreous detachment 1024:Persistent pupillary membrane 170:Cancer-associated retinopathy 1754:Leber's congenital amaurosis 1665:Internuclear ophthalmoplegia 1356:Vogt-Koyanagi-Harada disease 1341:Persistent fetal vasculature 1272:Leber's congenital amaurosis 553:Meibomian gland dysfunction 183:due to genetic mutation at 2040: 1277:Birdshot chorioretinopathy 1251:Central serous retinopathy 1069:Focal choroidal excavation 942:Corneal neovascularization 759:Subconjunctival hemorrhage 124:was the goddess of night. 1989: 1976: 1744: 1660:Convergence insufficiency 1533: 1402: 1385: 1372: 1301:Primary juvenile glaucoma 1146:Cytomegalovirus retinitis 788: 775: 561: 517: 504: 495:Diseases of the human eye 1170:Ocular ischemic syndrome 70:In hemeralopia, daytime 1670:One and a half syndrome 1424:Foster Kennedy syndrome 275:10.1136/bjo.2006.097519 1909:Argyll Robertson pupil 709:Periorbital cellulitis 1882:Scintillating scotoma 1548:Kearns–Sayre syndrome 1491:Toxic and nutritional 1464:posterior (PION) 947:Kayser–Fleischer ring 306:GördĂŒren, S. (1950). 1655:Conjugate gaze palsy 1526:Paralytic strabismus 1459:anterior (AION) 1241:Retinitis pigmentosa 1236:Macular degeneration 1009:Intermediate uveitis 925:Keratoconjunctivitis 363:Zihl, Josef (2000). 324:10.1136/bjo.34.9.563 148:are typical causes. 108:alaos, "blindness". 1960:Childhood blindness 1939:Parinaud's syndrome 1509:Extraocular muscles 1297:Ocular hypertension 1261:Epiretinal membrane 1246:Retinal haemorrhage 1101:Congenital cataract 104:hemera, "day", and 1486:Leber's hereditary 1153:Retinal detachment 1106:Childhood cataract 918:Post-LASIK ectasia 699:Orbital cellulitis 648:Lacrimal apparatus 2011: 2010: 2007: 2006: 1972: 1971: 1968: 1967: 1914:Marcus Gunn pupil 1890: 1889: 1811:Visual impairment 1678: 1677: 1584: 1583: 1571:Fourth-nerve (IV) 1499: 1498: 1436:Optic disc drusen 1368: 1367: 1364: 1363: 1082: 1081: 970: 969: 876:Corneal dystrophy 771: 770: 767: 766: 642: 641: 458: 457: 90:than in daytime. 67:to bright light. 46: 45: 16:Medical condition 2031: 1978: 1742: 1733:Vision disorders 1692:Refractive error 1634:Brown's syndrome 1590:Other strabismus 1576:Sixth-nerve (VI) 1566:Oculomotor (III) 1538:Ophthalmoparesis 1531: 1522: 1513:Binocular vision 1446:Optic neuropathy 1412:optic papillitis 1400: 1387: 1374: 1263:(Macular pucker) 981: 962:Band keratopathy 799: 790: 777: 704:Orbital lymphoma 591:Blepharophimosis 581:Blepharochalasis 528: 519: 506: 485: 478: 471: 462: 386: 379: 378: 359: 346: 345: 335: 303: 297: 296: 286: 254: 235:Adaptation (eye) 195:or retinal/iris 42: 41: 19: 2039: 2038: 2034: 2033: 2032: 2030: 2029: 2028: 2014: 2013: 2012: 2003: 1985: 1964: 1943: 1886: 1855: 1815: 1769:Color blindness 1735: 1727: 1674: 1648:Other binocular 1643: 1580: 1552: 1515: 1511: 1507: 1495: 1440: 1393: 1381: 1360: 1316:Ocular hypotony 1281: 1141:Chorioretinitis 1122: 1078: 1062:Chorioretinitis 1038: 1019:Rubeosis iridis 997: 966: 937:Corneal opacity 893:Corneal ectasia 820: 784: 763: 749:Pseudopterygium 713: 675: 638: 605: 601:Ankyloblepharon 557: 513: 500: 499: 489: 459: 454: 453: 397: 383: 382: 375: 362: 360: 349: 308:"Day-Blindness" 305: 304: 300: 263:Br J Ophthalmol 256: 255: 248: 243: 231: 212: 189:chorioretinitis 134: 97:comes from the 36: 17: 12: 11: 5: 2037: 2035: 2027: 2026: 2016: 2015: 2009: 2008: 2005: 2004: 2002: 2001: 1999:Onchocerciasis 1996: 1990: 1987: 1986: 1981: 1974: 1973: 1970: 1969: 1966: 1965: 1963: 1962: 1957: 1951: 1949: 1945: 1944: 1942: 1941: 1936: 1931: 1926: 1921: 1916: 1911: 1906: 1900: 1898: 1892: 1891: 1888: 1887: 1885: 1884: 1879: 1874: 1869: 1863: 1861: 1857: 1856: 1854: 1853: 1851:Quadrantanopia 1848: 1847: 1846: 1841: 1836: 1825: 1823: 1817: 1816: 1814: 1813: 1800: 1799: 1798: 1796:Oguchi disease 1788: 1787: 1786: 1781: 1776: 1766: 1761: 1756: 1751: 1745: 1739: 1729: 1728: 1726: 1725: 1720: 1711: 1706: 1705: 1704: 1699: 1688: 1686: 1680: 1679: 1676: 1675: 1673: 1672: 1667: 1662: 1657: 1651: 1649: 1645: 1644: 1642: 1641: 1639:Duane syndrome 1636: 1631: 1626: 1625: 1624: 1619: 1609: 1604: 1594: 1592: 1586: 1585: 1582: 1581: 1579: 1578: 1573: 1568: 1562: 1560: 1554: 1553: 1551: 1550: 1545: 1540: 1534: 1528: 1519: 1501: 1500: 1497: 1496: 1494: 1493: 1488: 1483: 1478: 1477: 1476: 1471: 1466: 1461: 1450: 1448: 1442: 1441: 1439: 1438: 1433: 1428: 1427: 1426: 1416: 1415: 1414: 1407:Optic neuritis 1403: 1397: 1383: 1382: 1377: 1370: 1369: 1366: 1365: 1362: 1361: 1359: 1358: 1353: 1348: 1343: 1338: 1336:Phthisis bulbi 1333: 1328: 1323: 1318: 1313: 1308: 1303: 1289: 1287: 1283: 1282: 1280: 1279: 1274: 1269: 1264: 1258: 1253: 1248: 1243: 1238: 1233: 1232: 1231: 1226: 1221: 1219:Coats' disease 1216: 1211: 1209:of prematurity 1206: 1201: 1196: 1186: 1181: 1176: 1167: 1162: 1161: 1160: 1150: 1149: 1148: 1143: 1132: 1130: 1124: 1123: 1121: 1120: 1118:Ectopia lentis 1115: 1110: 1109: 1108: 1103: 1092: 1090: 1084: 1083: 1080: 1079: 1077: 1076: 1071: 1066: 1065: 1064: 1054: 1048: 1046: 1040: 1039: 1037: 1036: 1031: 1026: 1021: 1016: 1011: 1006: 1000: 998: 996: 995: 990: 984: 978: 976:Vascular tunic 972: 971: 968: 967: 965: 964: 959: 954: 949: 944: 939: 934: 933: 932: 922: 921: 920: 915: 910: 905: 900: 890: 889: 888: 883: 873: 868: 863: 862: 861: 859:Photokeratitis 856: 851: 846: 841: 830: 828: 822: 821: 819: 818: 813: 807: 805: 796: 786: 785: 780: 773: 772: 769: 768: 765: 764: 762: 761: 756: 751: 746: 741: 740: 739: 732:Conjunctivitis 729: 723: 721: 715: 714: 712: 711: 706: 701: 696: 691: 685: 683: 677: 676: 674: 673: 668: 666:Dacryocystitis 663: 658: 656:Dacryoadenitis 652: 650: 644: 643: 640: 639: 637: 636: 631: 626: 621: 615: 613: 607: 606: 604: 603: 598: 593: 588: 583: 578: 573: 568: 562: 559: 558: 556: 555: 550: 545: 540: 534: 532: 525: 515: 514: 509: 502: 501: 498: 497: 491: 490: 488: 487: 480: 473: 465: 456: 455: 452: 451: 440: 429: 414: 398: 393: 392: 390: 389:Classification 381: 380: 373: 347: 318:(9): 563–567. 298: 269:(12): 1548–9. 245: 244: 242: 239: 238: 237: 230: 227: 211: 208: 177:Cohen syndrome 138:Cone dystrophy 133: 130: 82:as opposed to 44: 43: 30: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2036: 2025: 2022: 2021: 2019: 2000: 1997: 1995: 1992: 1991: 1988: 1984: 1979: 1975: 1961: 1958: 1956: 1953: 1952: 1950: 1946: 1940: 1937: 1935: 1932: 1930: 1927: 1925: 1922: 1920: 1919:Adie syndrome 1917: 1915: 1912: 1910: 1907: 1905: 1902: 1901: 1899: 1897: 1893: 1883: 1880: 1878: 1875: 1873: 1870: 1868: 1865: 1864: 1862: 1858: 1852: 1849: 1845: 1842: 1840: 1837: 1835: 1832: 1831: 1830: 1827: 1826: 1824: 1822: 1818: 1812: 1808: 1804: 1801: 1797: 1794: 1793: 1792: 1789: 1785: 1782: 1780: 1777: 1775: 1774:Achromatopsia 1772: 1771: 1770: 1767: 1765: 1762: 1760: 1757: 1755: 1752: 1750: 1747: 1746: 1743: 1740: 1738: 1734: 1730: 1724: 1721: 1719: 1715: 1714:Anisometropia 1712: 1710: 1707: 1703: 1700: 1698: 1695: 1694: 1693: 1690: 1689: 1687: 1685: 1681: 1671: 1668: 1666: 1663: 1661: 1658: 1656: 1653: 1652: 1650: 1646: 1640: 1637: 1635: 1632: 1630: 1627: 1623: 1620: 1618: 1615: 1614: 1613: 1610: 1608: 1605: 1603: 1599: 1596: 1595: 1593: 1591: 1587: 1577: 1574: 1572: 1569: 1567: 1564: 1563: 1561: 1559: 1555: 1549: 1546: 1544: 1541: 1539: 1536: 1535: 1532: 1529: 1527: 1523: 1520: 1518: 1517:Accommodation 1514: 1510: 1506: 1502: 1492: 1489: 1487: 1484: 1482: 1479: 1475: 1472: 1470: 1467: 1465: 1462: 1460: 1457: 1456: 1455: 1452: 1451: 1449: 1447: 1443: 1437: 1434: 1432: 1431:Optic atrophy 1429: 1425: 1422: 1421: 1420: 1417: 1413: 1410: 1409: 1408: 1405: 1404: 1401: 1398: 1396: 1392: 1388: 1384: 1380: 1375: 1371: 1357: 1354: 1352: 1349: 1347: 1344: 1342: 1339: 1337: 1334: 1332: 1331:Keratomycosis 1329: 1327: 1326:Globe rupture 1324: 1322: 1319: 1317: 1314: 1312: 1309: 1307: 1304: 1302: 1298: 1294: 1291: 1290: 1288: 1284: 1278: 1275: 1273: 1270: 1268: 1265: 1262: 1259: 1257: 1256:Macular edema 1254: 1252: 1249: 1247: 1244: 1242: 1239: 1237: 1234: 1230: 1227: 1225: 1222: 1220: 1217: 1215: 1212: 1210: 1207: 1205: 1202: 1200: 1197: 1195: 1192: 1191: 1190: 1187: 1185: 1182: 1180: 1177: 1175: 1171: 1168: 1166: 1165:Retinoschisis 1163: 1159: 1156: 1155: 1154: 1151: 1147: 1144: 1142: 1139: 1138: 1137: 1134: 1133: 1131: 1129: 1125: 1119: 1116: 1114: 1111: 1107: 1104: 1102: 1099: 1098: 1097: 1094: 1093: 1091: 1089: 1085: 1075: 1072: 1070: 1067: 1063: 1060: 1059: 1058: 1055: 1053: 1052:Choroideremia 1050: 1049: 1047: 1045: 1041: 1035: 1032: 1030: 1029:Iridodialysis 1027: 1025: 1022: 1020: 1017: 1015: 1012: 1010: 1007: 1005: 1002: 1001: 999: 994: 991: 989: 986: 985: 982: 979: 977: 973: 963: 960: 958: 957:Arcus senilis 955: 953: 952:Haab's striae 950: 948: 945: 943: 940: 938: 935: 931: 928: 927: 926: 923: 919: 916: 914: 911: 909: 906: 904: 901: 899: 896: 895: 894: 891: 887: 884: 882: 879: 878: 877: 874: 872: 869: 867: 866:Corneal ulcer 864: 860: 857: 855: 852: 850: 847: 845: 844:acanthamoebic 842: 840: 837: 836: 835: 832: 831: 829: 827: 823: 817: 814: 812: 809: 808: 806: 804: 800: 797: 795: 794:Fibrous tunic 791: 787: 783: 778: 774: 760: 757: 755: 752: 750: 747: 745: 742: 738: 735: 734: 733: 730: 728: 725: 724: 722: 720: 716: 710: 707: 705: 702: 700: 697: 695: 692: 690: 687: 686: 684: 682: 678: 672: 671:Xerophthalmia 669: 667: 664: 662: 659: 657: 654: 653: 651: 649: 645: 635: 632: 630: 627: 625: 622: 620: 617: 616: 614: 612: 608: 602: 599: 597: 594: 592: 589: 587: 584: 582: 579: 577: 576:Lagophthalmos 574: 572: 569: 567: 564: 563: 560: 554: 551: 549: 546: 544: 541: 539: 536: 535: 533: 529: 526: 524: 520: 516: 512: 507: 503: 496: 493: 492: 486: 481: 479: 474: 472: 467: 466: 463: 450: 446: 445: 441: 439: 435: 434: 430: 428: 424: 423: 419: 415: 413: 409: 408: 404: 400: 399: 396: 391: 387: 376: 374:0-86377-898-4 370: 366: 358: 356: 354: 352: 348: 343: 339: 334: 329: 325: 321: 317: 313: 309: 302: 299: 294: 290: 285: 280: 276: 272: 268: 264: 260: 253: 251: 247: 240: 236: 233: 232: 228: 226: 223: 221: 217: 209: 207: 205: 200: 198: 194: 193:optic atrophy 190: 186: 182: 178: 173: 171: 167: 163: 159: 155: 151: 147: 146:trimethadione 143: 142:achromatopsia 139: 131: 129: 127: 123: 119: 115: 114:Greek goddess 111: 107: 103: 100: 96: 91: 89: 85: 81: 77: 73: 68: 66: 62: 58: 54: 53:day blindness 50: 40: 34: 33:Ophthalmology 31: 29: 25: 20: 1871: 1809: / 1805: / 1784:Monochromacy 1716: / 1612:Heterophoria 1600: / 1299: / 1295: / 1199:hypertensive 1172: / 993:Ciliary body 908:Keratoglobus 816:Episcleritis 694:Enophthalmos 689:Exophthalmos 634:Trichomegaly 629:Distichiasis 531:Inflammation 442: 431: 416: 401: 364: 361:Page 96 in: 315: 311: 301: 266: 262: 224: 213: 201: 174: 150:Adie's pupil 135: 125: 105: 101: 94: 92: 69: 60: 52: 48: 47: 1934:Cycloplegia 1877:Photophobia 1872:Hemeralopia 1829:Hemianopsia 1807:Vision loss 1718:Aniseikonia 1709:Astigmatism 1629:Cyclotropia 1607:Hypertropia 1419:Papilledema 1391:Optic nerve 1224:Sickle cell 1204:Purtscher's 1189:Retinopathy 1057:Choroiditis 898:Keratoconus 719:Conjunctiva 596:Xanthelasma 548:Blepharitis 220:photophobia 181:dysmorphism 126:Hemeralopia 95:hemeralopia 76:photophobia 61:heliophobia 49:Hemeralopia 22:Hemeralopia 1983:Infections 1904:Anisocoria 1867:Asthenopia 1860:subjective 1844:homonymous 1839:bitemporal 1791:Nyctalopia 1779:Dichromacy 1723:Presbyopia 1684:Refraction 1505:Strabismus 1395:Optic disc 754:Pinguecula 619:Trichiasis 241:References 216:sunglasses 210:Management 204:chiasmatic 65:adaptation 57:nyctalopia 1955:Nystagmus 1929:Mydriasis 1803:Blindness 1749:Amblyopia 1737:Blindness 1697:Hyperopia 1622:Exophoria 1617:Esophoria 1602:Exotropia 1598:Esotropia 1136:Retinitis 834:Keratitis 811:Scleritis 744:Pterygium 624:Madarosis 571:Ectropion 566:Entropion 543:Chalazion 162:cataracts 93:The word 28:Specialty 2018:Category 1994:Trachoma 1759:Diplopia 1454:Ischemic 1379:Pathways 1293:Glaucoma 1194:diabetic 1096:Cataract 1034:Synechia 886:Meesmann 854:Exposure 839:herpetic 737:allergic 727:Chemosis 661:Epiphora 342:14777856 293:17114591 229:See also 197:coloboma 158:albinism 154:aniridia 112:was the 1834:binasal 1821:Anopsia 1764:Scotoma 1558:palsies 1321:Red eye 1306:Floater 1113:Aphakia 1044:Choroid 1014:Hyphema 1004:Uveitis 611:Eyelash 449:D014780 333:1323631 284:1857511 1924:Miosis 1702:Myopia 1481:Kjer's 1229:photic 1128:Retina 881:Fuchs' 849:fungal 826:Cornea 803:Sclera 586:Ptosis 523:Eyelid 511:Adnexa 438:310500 371:  340:  330:  291:  281:  166:retina 132:Causes 120:, and 110:Hemera 72:vision 35:  1948:Other 1896:Pupil 1286:Other 930:sicca 782:Globe 681:Orbit 427:368.6 412:H53.1 185:locus 106:αλαός 102:ηΌέρα 99:Greek 84:cones 1088:Lens 988:Iris 538:Stye 444:MeSH 433:OMIM 422:9-CM 369:ISBN 338:PMID 289:PMID 140:and 88:dusk 80:rods 418:ICD 403:ICD 328:PMC 320:doi 279:PMC 271:doi 122:Nyx 118:day 116:of 51:or 2020:: 447:: 436:: 425:: 410:: 407:10 350:^ 336:. 326:. 316:34 314:. 310:. 287:. 277:. 267:90 265:. 261:. 249:^ 222:. 191:, 484:e 477:t 470:v 420:- 405:- 395:D 377:. 344:. 322:: 295:. 273::

Index

Specialty
Ophthalmology
Edit this on Wikidata
nyctalopia
adaptation
vision
photophobia
rods
cones
dusk
Greek
Hemera
Greek goddess
day
Nyx
Cone dystrophy
achromatopsia
trimethadione
Adie's pupil
aniridia
albinism
cataracts
retina
Cancer-associated retinopathy
Cohen syndrome
dysmorphism
locus
chorioretinitis
optic atrophy
coloboma

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