Knowledge (XXG)

Biliary tract

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at the small intestine. The function of the common bile duct is to allow bile to travel from the gallbladder to the small intestine, mixing with pancreatic digestive enzymes along the way. One possible complication of choledocholithiasis is an infection of the bile ducts between the liver and the
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The system is usually referred to as the biliary tract or system, and can include the use of the term "hepatobiliary" when used to refer just to the liver and bile ducts. The name biliary tract is used to refer to all of the ducts, structures and organs involved in the production, storage and
417:. Between meals, secreted bile is stored in the gall bladder, where 80–90% of the water and electrolytes can be absorbed, leaving the bile acids and cholesterol. During a meal, the smooth muscles in the gallbladder wall contract, causing bile to be secreted into the 507:, which includes fever, right upper quadrant abdominal pain, and jaundice. This constellation of symptoms has a 96% specificity for cholangitis, and can be expanded upon with the addition of hypotension and altered mental status to form 522:
due to infection and inflammation of the biliary tract is not a somatic pain. Rather, pain may be caused by luminal distension, which causes stretching of the wall. This is the same mechanism that causes pain in
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Chronic inflammatory conditions of the biliary tract, including Primary Sclerosing Cholangitis (PSC) and Primary Biliary Cirrhosis (PBC), can lead to hardening of the ducts in the biliary tree.
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Occasionally gallstones may become lodged in the common bile duct and obstruct the flow of bile from the gallbladder to the small intestine– this condition is known as
91: 1123: 41: 885: 750: 566: 490:. The common bile duct, commonly abbreviated CBD, is formed by the union of the cystic duct and common hepatic duct, and it later joins the 448:
can form within the gallbladder and get stuck within the biliary tract, leading to various diseases depending on the location of the stone.
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The biliary tract can also serve as a reservoir for intestinal tract infections. Since the biliary tract is an internal organ, it has no
1116: 1000:"Colon distention induces persistent visceral hypersensitivity by mechanotranscription of pain mediators in colonic smooth muscle cells" 766:
Jurkovich, G. J.; Hoyt, D. B.; Moore, F. A.; Ney, A. L.; Morris, J. A.; Scalea, T. M.; Pachter, H. L.; Davis, J. W. (September 1995).
626: 367:>> intrahepatic bile ductule (in portal tracts / triads) >> interlobular bile ducts >> left and right hepatic ducts 1253: 437: 504: 86: 1403: 916:
Lam, Robert; Zakko, Alan; Petrov, Jessica C.; Kumar, Priyanka; Duffy, Andrew J.; Muniraj, Thiruvengadam (July 2021).
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family, the biliary tract is often referred to as a tree because it begins with many small branches that end in the
1198: 1419: 283: 471:, and can lead to inflammation in the wall of the gallbladder. This inflammation of the gallbladder is known as 1439: 863: 74: 1297: 1282: 1176: 205: 1191: 1156: 1140: 515: 235: 174:. Between meals, secreted bile is stored in the gallbladder. During a meal, the bile is secreted into the 98: 1243: 1186: 338: 1203: 160: 1049:"Biliary tract inflammatory disorders: primary sclerosing cholangitis and primary biliary cirrhosis" 321:
The biliary tract refers to the path by which bile is secreted by the liver then transported to the
1462: 1314: 508: 483: 414: 377: 371: 342: 245: 215: 171: 1108: 745:. Brown JL, Moore LA (40th ed.). London: Churchill Livingstone. pp. 1163, 1177, 1185–6. 1309: 1166: 249: 178:(part of the small intestine) to rid the body of waste stored in the bile as well as aid in the 349:. Bile flows in the direction opposite to that of the blood present in the other two channels. 1434: 1429: 1347: 1304: 1076: 1068: 1029: 975: 945: 937: 881: 842: 834: 795: 787: 746: 718: 684: 676: 622: 594: 562: 524: 500: 190: 1399: 1394: 1389: 1384: 1342: 1337: 1292: 1287: 1225: 1213: 1060: 1019: 1011: 929: 826: 779: 668: 495: 468: 401: 391: 364: 334: 230: 225: 1414: 491: 487: 476: 395: 360: 326: 295: 288: 859: 441:
Union of common bile duct and pancreatic duct terminating at duodenum (small intestine).
337:, sometimes referred to as the trunk of the biliary tree. The duct, the branches of the 1357: 1208: 1181: 1094: 1024: 999: 460: 453: 1456: 1230: 1171: 783: 519: 472: 210: 933: 17: 1248: 1220: 1161: 815:"Bile acid regulation of hepatic physiology: I. Hepatocyte transport of bile acids" 385: 346: 156: 132: 79: 1332: 1324: 464: 381: 240: 220: 152: 144: 967: 710: 586: 1238: 1064: 672: 426: 164: 136: 1072: 1015: 941: 838: 830: 791: 709:
Jones, Mark W.; Small, Kaitlynn; Kashyap, Sarang; Deppen, Jeffrey G. (2022),
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Hassler, Kenneth R.; Collins, Jason T.; Philip, Ken; Jones, Mark W. (2022),
449: 445: 422: 263: 197: 179: 148: 1080: 1048: 1033: 979: 949: 917: 846: 814: 722: 688: 656: 598: 799: 767: 1373: 534: 456:, is very common in the United States, impacting over 20 million people. 418: 322: 303: 275: 175: 104: 475:
and is a common indication for surgical removal of the gallbladder, or
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Gallstones frequently occur without causing symptoms– this is known as
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and is commonly associated with a triad of clinical symptoms known as
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American Journal of Physiology. Gastrointestinal and Liver Physiology
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American Journal of Physiology. Gastrointestinal and Liver Physiology
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gallstone lodged in the common bile duct. This condition is known as
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Bile is secreted by the liver into small ducts that join to form the
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Bile is secreted by the liver into small ducts that join to form the
167:(liver cells); the rest are extracted from the blood by the liver. 1148: 436: 421:
to rid the body of waste stored in the bile as well as aid in the
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The front border of the liver has been lifted up (brown arrow).
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Gray's anatomy : the anatomical basis of clinical practice
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Lin YM, Fu Y, Wu CC, Xu GY, Huang LY, Shi XZ (March 2015).
467:, which serves as a bridge between the gallbladder and the 655:
Vakili, Khashayar; Pomfret, Elizabeth A. (December 2008).
139:, and how they work together to make, store and secrete 27:
Organ system which creates, stores, and transports bile
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Wolkoff, Allan W.; Cohen, David E. (February 2003).
1372: 1323: 1273: 1264: 1147: 585:Hundt, Melanie; Basit, Hajira; John, Savio (2022), 85: 73: 68: 56: 51: 34: 537:, a yellowing of the skin and whites of the eyes. 533:An obstruction of the biliary tract can result in 974:, Treasure Island (FL): StatPearls Publishing, 918:"Gallbladder Disorders: A Comprehensive Review" 717:, Treasure Island (FL): StatPearls Publishing, 621:(21st ed.). Elsevier. pp. 1489–1527. 593:, Treasure Island (FL): StatPearls Publishing, 1124: 8: 463:. Sometimes gallstones may get stuck in the 329:. A structure common to most members of the 1270: 1131: 1117: 1109: 40: 1023: 880:(32nd ed.). Elsevier. p. 1946. 862:at the U.S. National Library of Medicine 878:Dorland's Illustrated Medical Dictionary 561:(32nd ed.). Elsevier. p. 846. 559:Dorland's Illustrated Medical Dictionary 189: 546: 102: 31: 1047:Franco, J.; Saeian, K. (April 1999). 961: 959: 911: 909: 907: 905: 903: 901: 899: 897: 741:Standring S, Borley NR, eds. (2008). 661:The Surgical Clinics of North America 163:. Some components are synthesized by 7: 704: 702: 700: 698: 650: 648: 646: 644: 642: 640: 638: 580: 578: 552: 550: 423:absorption of dietary fats and oils 380:exits the liver and joins with the 307:      20. 302:      19. 287:      17. 282:      16. 180:absorption of dietary fats and oils 234:      8. 229:      7. 224:      6. 219:      5. 214:      4. 209:      3. 204:      2. 25: 1254:Liver sinusoidal endothelial cell 1141:liver, pancreas and biliary tree 1053:Current Gastroenterology Reports 784:10.1097/00005373-199509000-00005 657:"Biliary anatomy and embryology" 934:10.1016/j.disamonth.2021.101130 968:"Laparoscopic Cholecystectomy" 486:and is another indication for 64:, which aids in fat absorption 1: 345:form the central axis of the 619:Sabiston Textbook of Surgery 587:"Physiology, Bile Secretion" 211:Left and right hepatic ducts 1095:"Definition: biliary tract" 461:asymptomatic cholelithiasis 425:by solubilizing them using 1479: 1199:Fibrous capsule of Glisson 356:The tract is as follows: 143:. Bile consists of water, 46:Ducts of the biliary tract 1099:Online Medical Dictionary 1065:10.1007/s11894-996-0006-8 711:"Physiology, Gallbladder" 673:10.1016/j.suc.2008.07.001 284:Accessory pancreatic duct 97: 39: 1016:10.1152/ajpgi.00328.2014 864:Medical Subject Headings 831:10.1152/ajpgi.00409.2002 390:Together these form the 370:These merge to form the 325:, the first part of the 1283:Intrahepatic bile ducts 768:"Portal triad injuries" 400:These pass through the 206:Intrahepatic bile ducts 60:Facilitate movement of 442: 404:and enter the duodenum 318: 312:21–22. Right and left 236:Major duodenal papilla 99:Anatomical terminology 1244:Hepatic stellate cell 772:The Journal of Trauma 667:(6): 1159–1174, vii. 440: 433:Clinical significance 193: 1204:Perisinusoidal space 516:somatic nerve supply 494:to terminate in the 161:conjugated bilirubin 18:Hepatobiliary system 1315:Common hepatic duct 876:Dorland WA (2012). 617:Townsend C (2022). 557:Dorland WA (2012). 484:choledocholithiasis 415:common hepatic duct 378:common hepatic duct 372:common hepatic duct 353:secretion of bile. 216:Common hepatic duct 172:common hepatic duct 1310:Right hepatic duct 1167:Ligamentum venosum 525:bowel obstructions 443: 319: 1450: 1449: 1435:Centroacinar cell 1430:Pancreatic islets 1368: 1367: 1348:Sphincter of Oddi 1305:Left hepatic duct 887:978-1-4160-6257-8 752:978-0-8089-2371-8 568:978-1-4160-6257-8 501:acute cholangitis 450:Gallstone disease 113: 112: 108: 16:(Redirected from 1470: 1404:Uncinate process 1343:Ampulla of Vater 1338:Common bile duct 1293:Canals of Hering 1288:Bile canaliculus 1271: 1226:Lobules of liver 1214:Periportal space 1133: 1126: 1119: 1110: 1103: 1102: 1091: 1085: 1084: 1044: 1038: 1037: 1027: 1010:(5): G434–G441. 995: 989: 988: 987: 986: 963: 954: 953: 913: 892: 891: 873: 867: 857: 851: 850: 810: 804: 803: 763: 757: 756: 738: 732: 731: 730: 729: 706: 693: 692: 652: 633: 632: 614: 608: 607: 606: 605: 582: 573: 572: 554: 509:Reynold's Pentad 496:Ampulla of Vater 469:common bile duct 402:ampulla of Vater 394:which joins the 392:common bile duct 365:Canals of Hering 335:common bile duct 231:Ampulla of Vater 226:Common bile duct 127:) refers to the 105:edit on Wikidata 44: 32: 21: 1478: 1477: 1473: 1472: 1471: 1469: 1468: 1467: 1453: 1452: 1451: 1446: 1364: 1319: 1260: 1143: 1139:Anatomy of the 1137: 1107: 1106: 1093: 1092: 1088: 1046: 1045: 1041: 997: 996: 992: 984: 982: 965: 964: 957: 922:Disease-a-Month 915: 914: 895: 888: 875: 874: 870: 858: 854: 825:(2): G175–179. 812: 811: 807: 765: 764: 760: 753: 740: 739: 735: 727: 725: 708: 707: 696: 654: 653: 636: 629: 616: 615: 611: 603: 601: 584: 583: 576: 569: 556: 555: 548: 543: 505:Charcot's Triad 492:pancreatic duct 488:cholecystectomy 477:cholecystectomy 435: 411: 396:pancreatic duct 361:Bile canaliculi 327:small intestine 316: 311: 306: 301: 296:Small intestine 291: 289:Pancreatic duct 286: 281: 271: 266: 261: 256: 243: 238: 233: 228: 223: 218: 213: 208: 203: 188: 109: 47: 28: 23: 22: 15: 12: 11: 5: 1476: 1474: 1466: 1465: 1455: 1454: 1448: 1447: 1445: 1444: 1443: 1442: 1437: 1432: 1424: 1423: 1422: 1417: 1409: 1408: 1407: 1397: 1392: 1387: 1378: 1376: 1370: 1369: 1366: 1365: 1363: 1362: 1361: 1360: 1358:Cholecystocyte 1352: 1351: 1350: 1340: 1335: 1329: 1327: 1321: 1320: 1318: 1317: 1312: 1307: 1302: 1301: 1300: 1295: 1290: 1279: 1277: 1268: 1262: 1261: 1259: 1258: 1257: 1256: 1251: 1246: 1241: 1233: 1228: 1223: 1218: 1217: 1216: 1209:Liver sinusoid 1206: 1201: 1196: 1195: 1194: 1189: 1182:Lobes of liver 1179: 1177:Round ligament 1174: 1169: 1164: 1159: 1153: 1151: 1145: 1144: 1138: 1136: 1135: 1128: 1121: 1113: 1105: 1104: 1086: 1039: 990: 955: 893: 886: 868: 852: 805: 778:(3): 426–434. 758: 751: 733: 694: 634: 628:978-0275972837 627: 609: 574: 567: 545: 544: 542: 539: 454:cholelithiasis 434: 431: 410: 407: 406: 405: 398: 388: 374: 368: 339:hepatic artery 187: 184: 125:biliary system 111: 110: 101: 95: 94: 89: 83: 82: 77: 71: 70: 66: 65: 58: 54: 53: 49: 48: 45: 37: 36: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 1475: 1464: 1461: 1460: 1458: 1441: 1440:Stellate cell 1438: 1436: 1433: 1431: 1428: 1427: 1426:Microanatomy 1425: 1421: 1418: 1416: 1413: 1412: 1410: 1405: 1401: 1398: 1396: 1393: 1391: 1388: 1386: 1383: 1382: 1380: 1379: 1377: 1375: 1371: 1359: 1356: 1355: 1353: 1349: 1346: 1345: 1344: 1341: 1339: 1336: 1334: 1331: 1330: 1328: 1326: 1322: 1316: 1313: 1311: 1308: 1306: 1303: 1299: 1296: 1294: 1291: 1289: 1286: 1285: 1284: 1281: 1280: 1278: 1276: 1272: 1269: 1267: 1266:Biliary tract 1263: 1255: 1252: 1250: 1247: 1245: 1242: 1240: 1237: 1236: 1235:Microanatomy 1234: 1232: 1231:Liver segment 1229: 1227: 1224: 1222: 1219: 1215: 1212: 1211: 1210: 1207: 1205: 1202: 1200: 1197: 1193: 1190: 1188: 1185: 1184: 1183: 1180: 1178: 1175: 1173: 1172:Porta hepatis 1170: 1168: 1165: 1163: 1160: 1158: 1155: 1154: 1152: 1150: 1146: 1142: 1134: 1129: 1127: 1122: 1120: 1115: 1114: 1111: 1100: 1096: 1090: 1087: 1082: 1078: 1074: 1070: 1066: 1062: 1059:(2): 95–101. 1058: 1054: 1050: 1043: 1040: 1035: 1031: 1026: 1021: 1017: 1013: 1009: 1005: 1001: 994: 991: 981: 977: 973: 969: 962: 960: 956: 951: 947: 943: 939: 935: 931: 928:(7): 101130. 927: 923: 919: 912: 910: 908: 906: 904: 902: 900: 898: 894: 889: 883: 879: 872: 869: 865: 861: 860:Biliary+tract 856: 853: 848: 844: 840: 836: 832: 828: 824: 820: 816: 809: 806: 801: 797: 793: 789: 785: 781: 777: 773: 769: 762: 759: 754: 748: 744: 737: 734: 724: 720: 716: 712: 705: 703: 701: 699: 695: 690: 686: 682: 678: 674: 670: 666: 662: 658: 651: 649: 647: 645: 643: 641: 639: 635: 630: 624: 620: 613: 610: 600: 596: 592: 588: 581: 579: 575: 570: 564: 560: 553: 551: 547: 540: 538: 536: 531: 528: 526: 521: 520:biliary colic 517: 512: 510: 506: 502: 497: 493: 489: 485: 480: 478: 474: 473:cholecystitis 470: 466: 462: 457: 455: 451: 447: 439: 432: 430: 428: 424: 420: 416: 408: 403: 399: 397: 393: 389: 387: 383: 379: 375: 373: 369: 366: 362: 359: 358: 357: 354: 350: 348: 344: 340: 336: 332: 328: 324: 315: 310: 305: 299: 298: 297: 290: 285: 279: 278: 277: 270: 265: 260: 255: 251: 247: 242: 237: 232: 227: 222: 217: 212: 207: 201: 200: 199: 192: 185: 183: 181: 177: 173: 168: 166: 162: 158: 157:phospholipids 154: 150: 146: 142: 138: 134: 130: 126: 122: 118: 117:biliary tract 106: 100: 96: 93: 90: 88: 84: 81: 78: 76: 72: 67: 63: 59: 55: 50: 43: 38: 35:Biliary tract 33: 30: 19: 1298:Interlobular 1265: 1249:Kupffer cell 1221:Portal triad 1162:Cantlie line 1098: 1089: 1056: 1052: 1042: 1007: 1003: 993: 983:, retrieved 971: 925: 921: 877: 871: 855: 822: 818: 808: 775: 771: 761: 742: 736: 726:, retrieved 714: 664: 660: 618: 612: 602:, retrieved 590: 558: 532: 529: 513: 481: 458: 444: 412: 386:gall bladder 355: 351: 347:portal triad 320: 294: 293: 274: 273: 196: 195: 169: 145:electrolytes 124: 121:biliary tree 120: 116: 114: 29: 1333:Cystic duct 1325:Gallbladder 465:cystic duct 382:cystic duct 343:portal vein 241:Gallbladder 221:Cystic duct 165:hepatocytes 153:cholesterol 133:gallbladder 69:Identifiers 1463:Hepatology 1275:Bile ducts 1239:Hepatocyte 985:2022-11-03 972:StatPearls 728:2022-11-03 715:StatPearls 604:2022-11-14 591:StatPearls 541:References 446:Gallstones 427:bile acids 341:, and the 198:Bile ducts 149:bile acids 137:bile ducts 1420:accessory 1157:Bare area 1073:1522-8037 942:1557-8194 839:0193-1857 792:0022-5282 681:0039-6109 363:>> 264:Esophagus 252:lobes of 186:Structure 1457:Category 1374:Pancreas 1192:Quadrate 1081:10980934 1034:25540231 980:28846328 950:33478678 847:12529265 723:29494095 689:18992589 599:29262229 535:jaundice 419:duodenum 409:Function 323:duodenum 304:Duodenum 276:Pancreas 176:duodenum 57:Function 1187:Caudate 1025:4346753 800:7473903 314:kidneys 309:Jejunum 269:Stomach 244:10–11. 80:D001659 52:Details 1411:Ducts 1381:Gross 1354:Cells 1079:  1071:  1032:  1022:  978:  948:  940:  884:  866:(MeSH) 845:  837:  798:  790:  749:  721:  687:  679:  625:  597:  565:  518:, and 331:mammal 259:Spleen 119:(also 1149:Liver 452:, or 384:from 254:liver 246:Right 129:liver 103:[ 92:79646 1415:main 1400:Head 1395:Neck 1390:Body 1385:Tail 1077:PMID 1069:ISSN 1030:PMID 976:PMID 946:PMID 938:ISSN 882:ISBN 843:PMID 835:ISSN 796:PMID 788:ISSN 747:ISBN 719:PMID 685:PMID 677:ISSN 623:ISBN 595:PMID 563:ISBN 376:The 292:18. 272:15. 267:14. 262:13. 257:12. 250:left 248:and 159:and 141:bile 135:and 115:The 75:MeSH 62:bile 1061:doi 1020:PMC 1012:doi 1008:308 930:doi 827:doi 823:284 780:doi 669:doi 239:9. 194:1. 123:or 87:FMA 1459:: 1097:. 1075:. 1067:. 1055:. 1051:. 1028:. 1018:. 1006:. 1002:. 970:, 958:^ 944:. 936:. 926:67 924:. 920:. 896:^ 841:. 833:. 821:. 817:. 794:. 786:. 776:39 774:. 770:. 713:, 697:^ 683:. 675:. 665:88 663:. 659:. 637:^ 589:, 577:^ 549:^ 527:. 511:. 479:. 429:. 300:: 280:: 202:: 182:. 155:, 151:, 147:, 131:, 1406:) 1402:( 1132:e 1125:t 1118:v 1101:. 1083:. 1063:: 1057:1 1036:. 1014:: 952:. 932:: 890:. 849:. 829:: 802:. 782:: 755:. 691:. 671:: 631:. 571:. 107:] 20:)

Index

Hepatobiliary system

bile
MeSH
D001659
FMA
79646
Anatomical terminology
edit on Wikidata
liver
gallbladder
bile ducts
bile
electrolytes
bile acids
cholesterol
phospholipids
conjugated bilirubin
hepatocytes
common hepatic duct
duodenum
absorption of dietary fats and oils

Bile ducts
Intrahepatic bile ducts
Left and right hepatic ducts
Common hepatic duct
Cystic duct
Common bile duct
Ampulla of Vater

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