42:
438:
191:
498:
at the small intestine. The function of the common bile duct is to allow bile to travel from the gallbladder to the small intestine, mixing with pancreatic digestive enzymes along the way. One possible complication of choledocholithiasis is an infection of the bile ducts between the liver and the
352:
The system is usually referred to as the biliary tract or system, and can include the use of the term "hepatobiliary" when used to refer just to the liver and bile ducts. The name biliary tract is used to refer to all of the ducts, structures and organs involved in the production, storage and
417:. Between meals, secreted bile is stored in the gall bladder, where 80–90% of the water and electrolytes can be absorbed, leaving the bile acids and cholesterol. During a meal, the smooth muscles in the gallbladder wall contract, causing bile to be secreted into the
507:, which includes fever, right upper quadrant abdominal pain, and jaundice. This constellation of symptoms has a 96% specificity for cholangitis, and can be expanded upon with the addition of hypotension and altered mental status to form
522:
due to infection and inflammation of the biliary tract is not a somatic pain. Rather, pain may be caused by luminal distension, which causes stretching of the wall. This is the same mechanism that causes pain in
530:
Chronic inflammatory conditions of the biliary tract, including
Primary Sclerosing Cholangitis (PSC) and Primary Biliary Cirrhosis (PBC), can lead to hardening of the ducts in the biliary tree.
1130:
482:
Occasionally gallstones may become lodged in the common bile duct and obstruct the flow of bile from the gallbladder to the small intestine– this condition is known as
91:
1123:
41:
885:
750:
566:
490:. The common bile duct, commonly abbreviated CBD, is formed by the union of the cystic duct and common hepatic duct, and it later joins the
448:
can form within the gallbladder and get stuck within the biliary tract, leading to various diseases depending on the location of the stone.
514:
The biliary tract can also serve as a reservoir for intestinal tract infections. Since the biliary tract is an internal organ, it has no
1116:
1000:"Colon distention induces persistent visceral hypersensitivity by mechanotranscription of pain mediators in colonic smooth muscle cells"
766:
Jurkovich, G. J.; Hoyt, D. B.; Moore, F. A.; Ney, A. L.; Morris, J. A.; Scalea, T. M.; Pachter, H. L.; Davis, J. W. (September 1995).
626:
367:>> intrahepatic bile ductule (in portal tracts / triads) >> interlobular bile ducts >> left and right hepatic ducts
1253:
437:
504:
86:
1403:
916:
Lam, Robert; Zakko, Alan; Petrov, Jessica C.; Kumar, Priyanka; Duffy, Andrew J.; Muniraj, Thiruvengadam (July 2021).
333:
family, the biliary tract is often referred to as a tree because it begins with many small branches that end in the
1198:
1419:
283:
471:, and can lead to inflammation in the wall of the gallbladder. This inflammation of the gallbladder is known as
1439:
863:
74:
1297:
1282:
1176:
205:
1191:
1156:
1140:
515:
235:
174:. Between meals, secreted bile is stored in the gallbladder. During a meal, the bile is secreted into the
98:
1243:
1186:
338:
1203:
160:
1049:"Biliary tract inflammatory disorders: primary sclerosing cholangitis and primary biliary cirrhosis"
321:
The biliary tract refers to the path by which bile is secreted by the liver then transported to the
1462:
1314:
508:
483:
414:
377:
371:
342:
245:
215:
171:
1108:
745:. Brown JL, Moore LA (40th ed.). London: Churchill Livingstone. pp. 1163, 1177, 1185–6.
1309:
1166:
249:
178:(part of the small intestine) to rid the body of waste stored in the bile as well as aid in the
349:. Bile flows in the direction opposite to that of the blood present in the other two channels.
1434:
1429:
1347:
1304:
1076:
1068:
1029:
975:
945:
937:
881:
842:
834:
795:
787:
746:
718:
684:
676:
622:
594:
562:
524:
500:
190:
1399:
1394:
1389:
1384:
1342:
1337:
1292:
1287:
1225:
1213:
1060:
1019:
1011:
929:
826:
779:
668:
495:
468:
401:
391:
364:
334:
230:
225:
1414:
491:
487:
476:
395:
360:
326:
295:
288:
859:
441:
Union of common bile duct and pancreatic duct terminating at duodenum (small intestine).
337:, sometimes referred to as the trunk of the biliary tree. The duct, the branches of the
1357:
1208:
1181:
1094:
1024:
999:
460:
453:
1456:
1230:
1171:
783:
519:
472:
210:
933:
17:
1248:
1220:
1161:
815:"Bile acid regulation of hepatic physiology: I. Hepatocyte transport of bile acids"
385:
346:
156:
132:
79:
1332:
1324:
464:
381:
240:
220:
152:
144:
967:
710:
586:
1238:
1064:
672:
426:
164:
136:
1072:
1015:
941:
838:
830:
791:
709:
Jones, Mark W.; Small, Kaitlynn; Kashyap, Sarang; Deppen, Jeffrey G. (2022),
680:
1274:
966:
Hassler, Kenneth R.; Collins, Jason T.; Philip, Ken; Jones, Mark W. (2022),
449:
445:
422:
263:
197:
179:
148:
1080:
1048:
1033:
979:
949:
917:
846:
814:
722:
688:
656:
598:
799:
767:
1373:
534:
456:, is very common in the United States, impacting over 20 million people.
418:
322:
303:
275:
175:
104:
475:
and is a common indication for surgical removal of the gallbladder, or
459:
Gallstones frequently occur without causing symptoms– this is known as
308:
268:
503:
and is commonly associated with a triad of clinical symptoms known as
1004:
American
Journal of Physiology. Gastrointestinal and Liver Physiology
819:
American
Journal of Physiology. Gastrointestinal and Liver Physiology
499:
gallstone lodged in the common bile duct. This condition is known as
413:
Bile is secreted by the liver into small ducts that join to form the
330:
313:
258:
170:
Bile is secreted by the liver into small ducts that join to form the
167:(liver cells); the rest are extracted from the blood by the liver.
1148:
436:
421:
to rid the body of waste stored in the bile as well as aid in the
253:
128:
317:
The front border of the liver has been lifted up (brown arrow).
140:
61:
1112:
743:
Gray's anatomy : the anatomical basis of clinical practice
998:
Lin YM, Fu Y, Wu CC, Xu GY, Huang LY, Shi XZ (March 2015).
467:, which serves as a bridge between the gallbladder and the
655:
Vakili, Khashayar; Pomfret, Elizabeth A. (December 2008).
139:, and how they work together to make, store and secrete
27:
Organ system which creates, stores, and transports bile
813:
Wolkoff, Allan W.; Cohen, David E. (February 2003).
1372:
1323:
1273:
1264:
1147:
585:Hundt, Melanie; Basit, Hajira; John, Savio (2022),
85:
73:
68:
56:
51:
34:
537:, a yellowing of the skin and whites of the eyes.
533:An obstruction of the biliary tract can result in
974:, Treasure Island (FL): StatPearls Publishing,
918:"Gallbladder Disorders: A Comprehensive Review"
717:, Treasure Island (FL): StatPearls Publishing,
621:(21st ed.). Elsevier. pp. 1489–1527.
593:, Treasure Island (FL): StatPearls Publishing,
1124:
8:
463:. Sometimes gallstones may get stuck in the
329:. A structure common to most members of the
1270:
1131:
1117:
1109:
40:
1023:
880:(32nd ed.). Elsevier. p. 1946.
862:at the U.S. National Library of Medicine
878:Dorland's Illustrated Medical Dictionary
561:(32nd ed.). Elsevier. p. 846.
559:Dorland's Illustrated Medical Dictionary
189:
546:
102:
31:
1047:Franco, J.; Saeian, K. (April 1999).
961:
959:
911:
909:
907:
905:
903:
901:
899:
897:
741:Standring S, Borley NR, eds. (2008).
661:The Surgical Clinics of North America
163:. Some components are synthesized by
7:
704:
702:
700:
698:
650:
648:
646:
644:
642:
640:
638:
580:
578:
552:
550:
423:absorption of dietary fats and oils
380:exits the liver and joins with the
307: 20.
302: 19.
287: 17.
282: 16.
180:absorption of dietary fats and oils
234: 8.
229: 7.
224: 6.
219: 5.
214: 4.
209: 3.
204: 2.
25:
1254:Liver sinusoidal endothelial cell
1141:liver, pancreas and biliary tree
1053:Current Gastroenterology Reports
784:10.1097/00005373-199509000-00005
657:"Biliary anatomy and embryology"
934:10.1016/j.disamonth.2021.101130
968:"Laparoscopic Cholecystectomy"
486:and is another indication for
64:, which aids in fat absorption
1:
345:form the central axis of the
619:Sabiston Textbook of Surgery
587:"Physiology, Bile Secretion"
211:Left and right hepatic ducts
1095:"Definition: biliary tract"
461:asymptomatic cholelithiasis
425:by solubilizing them using
1479:
1199:Fibrous capsule of Glisson
356:The tract is as follows:
143:. Bile consists of water,
46:Ducts of the biliary tract
1099:Online Medical Dictionary
1065:10.1007/s11894-996-0006-8
711:"Physiology, Gallbladder"
673:10.1016/j.suc.2008.07.001
284:Accessory pancreatic duct
97:
39:
1016:10.1152/ajpgi.00328.2014
864:Medical Subject Headings
831:10.1152/ajpgi.00409.2002
390:Together these form the
370:These merge to form the
325:, the first part of the
1283:Intrahepatic bile ducts
768:"Portal triad injuries"
400:These pass through the
206:Intrahepatic bile ducts
60:Facilitate movement of
442:
404:and enter the duodenum
318:
312:21–22. Right and left
236:Major duodenal papilla
99:Anatomical terminology
1244:Hepatic stellate cell
772:The Journal of Trauma
667:(6): 1159–1174, vii.
440:
433:Clinical significance
193:
1204:Perisinusoidal space
516:somatic nerve supply
494:to terminate in the
161:conjugated bilirubin
18:Hepatobiliary system
1315:Common hepatic duct
876:Dorland WA (2012).
617:Townsend C (2022).
557:Dorland WA (2012).
484:choledocholithiasis
415:common hepatic duct
378:common hepatic duct
372:common hepatic duct
353:secretion of bile.
216:Common hepatic duct
172:common hepatic duct
1310:Right hepatic duct
1167:Ligamentum venosum
525:bowel obstructions
443:
319:
1450:
1449:
1435:Centroacinar cell
1430:Pancreatic islets
1368:
1367:
1348:Sphincter of Oddi
1305:Left hepatic duct
887:978-1-4160-6257-8
752:978-0-8089-2371-8
568:978-1-4160-6257-8
501:acute cholangitis
450:Gallstone disease
113:
112:
108:
16:(Redirected from
1470:
1404:Uncinate process
1343:Ampulla of Vater
1338:Common bile duct
1293:Canals of Hering
1288:Bile canaliculus
1271:
1226:Lobules of liver
1214:Periportal space
1133:
1126:
1119:
1110:
1103:
1102:
1091:
1085:
1084:
1044:
1038:
1037:
1027:
1010:(5): G434–G441.
995:
989:
988:
987:
986:
963:
954:
953:
913:
892:
891:
873:
867:
857:
851:
850:
810:
804:
803:
763:
757:
756:
738:
732:
731:
730:
729:
706:
693:
692:
652:
633:
632:
614:
608:
607:
606:
605:
582:
573:
572:
554:
509:Reynold's Pentad
496:Ampulla of Vater
469:common bile duct
402:ampulla of Vater
394:which joins the
392:common bile duct
365:Canals of Hering
335:common bile duct
231:Ampulla of Vater
226:Common bile duct
127:) refers to the
105:edit on Wikidata
44:
32:
21:
1478:
1477:
1473:
1472:
1471:
1469:
1468:
1467:
1453:
1452:
1451:
1446:
1364:
1319:
1260:
1143:
1139:Anatomy of the
1137:
1107:
1106:
1093:
1092:
1088:
1046:
1045:
1041:
997:
996:
992:
984:
982:
965:
964:
957:
922:Disease-a-Month
915:
914:
895:
888:
875:
874:
870:
858:
854:
825:(2): G175–179.
812:
811:
807:
765:
764:
760:
753:
740:
739:
735:
727:
725:
708:
707:
696:
654:
653:
636:
629:
616:
615:
611:
603:
601:
584:
583:
576:
569:
556:
555:
548:
543:
505:Charcot's Triad
492:pancreatic duct
488:cholecystectomy
477:cholecystectomy
435:
411:
396:pancreatic duct
361:Bile canaliculi
327:small intestine
316:
311:
306:
301:
296:Small intestine
291:
289:Pancreatic duct
286:
281:
271:
266:
261:
256:
243:
238:
233:
228:
223:
218:
213:
208:
203:
188:
109:
47:
28:
23:
22:
15:
12:
11:
5:
1476:
1474:
1466:
1465:
1455:
1454:
1448:
1447:
1445:
1444:
1443:
1442:
1437:
1432:
1424:
1423:
1422:
1417:
1409:
1408:
1407:
1397:
1392:
1387:
1378:
1376:
1370:
1369:
1366:
1365:
1363:
1362:
1361:
1360:
1358:Cholecystocyte
1352:
1351:
1350:
1340:
1335:
1329:
1327:
1321:
1320:
1318:
1317:
1312:
1307:
1302:
1301:
1300:
1295:
1290:
1279:
1277:
1268:
1262:
1261:
1259:
1258:
1257:
1256:
1251:
1246:
1241:
1233:
1228:
1223:
1218:
1217:
1216:
1209:Liver sinusoid
1206:
1201:
1196:
1195:
1194:
1189:
1182:Lobes of liver
1179:
1177:Round ligament
1174:
1169:
1164:
1159:
1153:
1151:
1145:
1144:
1138:
1136:
1135:
1128:
1121:
1113:
1105:
1104:
1086:
1039:
990:
955:
893:
886:
868:
852:
805:
778:(3): 426–434.
758:
751:
733:
694:
634:
628:978-0275972837
627:
609:
574:
567:
545:
544:
542:
539:
454:cholelithiasis
434:
431:
410:
407:
406:
405:
398:
388:
374:
368:
339:hepatic artery
187:
184:
125:biliary system
111:
110:
101:
95:
94:
89:
83:
82:
77:
71:
70:
66:
65:
58:
54:
53:
49:
48:
45:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1475:
1464:
1461:
1460:
1458:
1441:
1440:Stellate cell
1438:
1436:
1433:
1431:
1428:
1427:
1426:Microanatomy
1425:
1421:
1418:
1416:
1413:
1412:
1410:
1405:
1401:
1398:
1396:
1393:
1391:
1388:
1386:
1383:
1382:
1380:
1379:
1377:
1375:
1371:
1359:
1356:
1355:
1353:
1349:
1346:
1345:
1344:
1341:
1339:
1336:
1334:
1331:
1330:
1328:
1326:
1322:
1316:
1313:
1311:
1308:
1306:
1303:
1299:
1296:
1294:
1291:
1289:
1286:
1285:
1284:
1281:
1280:
1278:
1276:
1272:
1269:
1267:
1266:Biliary tract
1263:
1255:
1252:
1250:
1247:
1245:
1242:
1240:
1237:
1236:
1235:Microanatomy
1234:
1232:
1231:Liver segment
1229:
1227:
1224:
1222:
1219:
1215:
1212:
1211:
1210:
1207:
1205:
1202:
1200:
1197:
1193:
1190:
1188:
1185:
1184:
1183:
1180:
1178:
1175:
1173:
1172:Porta hepatis
1170:
1168:
1165:
1163:
1160:
1158:
1155:
1154:
1152:
1150:
1146:
1142:
1134:
1129:
1127:
1122:
1120:
1115:
1114:
1111:
1100:
1096:
1090:
1087:
1082:
1078:
1074:
1070:
1066:
1062:
1059:(2): 95–101.
1058:
1054:
1050:
1043:
1040:
1035:
1031:
1026:
1021:
1017:
1013:
1009:
1005:
1001:
994:
991:
981:
977:
973:
969:
962:
960:
956:
951:
947:
943:
939:
935:
931:
928:(7): 101130.
927:
923:
919:
912:
910:
908:
906:
904:
902:
900:
898:
894:
889:
883:
879:
872:
869:
865:
861:
860:Biliary+tract
856:
853:
848:
844:
840:
836:
832:
828:
824:
820:
816:
809:
806:
801:
797:
793:
789:
785:
781:
777:
773:
769:
762:
759:
754:
748:
744:
737:
734:
724:
720:
716:
712:
705:
703:
701:
699:
695:
690:
686:
682:
678:
674:
670:
666:
662:
658:
651:
649:
647:
645:
643:
641:
639:
635:
630:
624:
620:
613:
610:
600:
596:
592:
588:
581:
579:
575:
570:
564:
560:
553:
551:
547:
540:
538:
536:
531:
528:
526:
521:
520:biliary colic
517:
512:
510:
506:
502:
497:
493:
489:
485:
480:
478:
474:
473:cholecystitis
470:
466:
462:
457:
455:
451:
447:
439:
432:
430:
428:
424:
420:
416:
408:
403:
399:
397:
393:
389:
387:
383:
379:
375:
373:
369:
366:
362:
359:
358:
357:
354:
350:
348:
344:
340:
336:
332:
328:
324:
315:
310:
305:
299:
298:
297:
290:
285:
279:
278:
277:
270:
265:
260:
255:
251:
247:
242:
237:
232:
227:
222:
217:
212:
207:
201:
200:
199:
192:
185:
183:
181:
177:
173:
168:
166:
162:
158:
157:phospholipids
154:
150:
146:
142:
138:
134:
130:
126:
122:
118:
117:biliary tract
106:
100:
96:
93:
90:
88:
84:
81:
78:
76:
72:
67:
63:
59:
55:
50:
43:
38:
35:Biliary tract
33:
30:
19:
1298:Interlobular
1265:
1249:Kupffer cell
1221:Portal triad
1162:Cantlie line
1098:
1089:
1056:
1052:
1042:
1007:
1003:
993:
983:, retrieved
971:
925:
921:
877:
871:
855:
822:
818:
808:
775:
771:
761:
742:
736:
726:, retrieved
714:
664:
660:
618:
612:
602:, retrieved
590:
558:
532:
529:
513:
481:
458:
444:
412:
386:gall bladder
355:
351:
347:portal triad
320:
294:
293:
274:
273:
196:
195:
169:
145:electrolytes
124:
121:biliary tree
120:
116:
114:
29:
1333:Cystic duct
1325:Gallbladder
465:cystic duct
382:cystic duct
343:portal vein
241:Gallbladder
221:Cystic duct
165:hepatocytes
153:cholesterol
133:gallbladder
69:Identifiers
1463:Hepatology
1275:Bile ducts
1239:Hepatocyte
985:2022-11-03
972:StatPearls
728:2022-11-03
715:StatPearls
604:2022-11-14
591:StatPearls
541:References
446:Gallstones
427:bile acids
341:, and the
198:Bile ducts
149:bile acids
137:bile ducts
1420:accessory
1157:Bare area
1073:1522-8037
942:1557-8194
839:0193-1857
792:0022-5282
681:0039-6109
363:>>
264:Esophagus
252:lobes of
186:Structure
1457:Category
1374:Pancreas
1192:Quadrate
1081:10980934
1034:25540231
980:28846328
950:33478678
847:12529265
723:29494095
689:18992589
599:29262229
535:jaundice
419:duodenum
409:Function
323:duodenum
304:Duodenum
276:Pancreas
176:duodenum
57:Function
1187:Caudate
1025:4346753
800:7473903
314:kidneys
309:Jejunum
269:Stomach
244:10–11.
80:D001659
52:Details
1411:Ducts
1381:Gross
1354:Cells
1079:
1071:
1032:
1022:
978:
948:
940:
884:
866:(MeSH)
845:
837:
798:
790:
749:
721:
687:
679:
625:
597:
565:
518:, and
331:mammal
259:Spleen
119:(also
1149:Liver
452:, or
384:from
254:liver
246:Right
129:liver
103:[
92:79646
1415:main
1400:Head
1395:Neck
1390:Body
1385:Tail
1077:PMID
1069:ISSN
1030:PMID
976:PMID
946:PMID
938:ISSN
882:ISBN
843:PMID
835:ISSN
796:PMID
788:ISSN
747:ISBN
719:PMID
685:PMID
677:ISSN
623:ISBN
595:PMID
563:ISBN
376:The
292:18.
272:15.
267:14.
262:13.
257:12.
250:left
248:and
159:and
141:bile
135:and
115:The
75:MeSH
62:bile
1061:doi
1020:PMC
1012:doi
1008:308
930:doi
827:doi
823:284
780:doi
669:doi
239:9.
194:1.
123:or
87:FMA
1459::
1097:.
1075:.
1067:.
1055:.
1051:.
1028:.
1018:.
1006:.
1002:.
970:,
958:^
944:.
936:.
926:67
924:.
920:.
896:^
841:.
833:.
821:.
817:.
794:.
786:.
776:39
774:.
770:.
713:,
697:^
683:.
675:.
665:88
663:.
659:.
637:^
589:,
577:^
549:^
527:.
511:.
479:.
429:.
300::
280::
202::
182:.
155:,
151:,
147:,
131:,
1406:)
1402:(
1132:e
1125:t
1118:v
1101:.
1083:.
1063::
1057:1
1036:.
1014::
952:.
932::
890:.
849:.
829::
802:.
782::
755:.
691:.
671::
631:.
571:.
107:]
20:)
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