Knowledge (XXG)

Herpesvirus entry mediator

Source 📝

321: 298: 195: 220: 2495: 572: 36: 327: 226: 2510: 1716:
Morin RD, Mendez-Lago M, Mungall AJ, Goya R, Mungall KL, Corbett RD, Johnson NA, Severson TM, Chiu R, Field M, Jackman S, Krzywinski M, Scott DW, Trinh DL, Tamura-Wells J, Li S, Firme MR, Rogic S, Griffith M, Chan S, Yakovenko O, Meyer IM, Zhao EY, Smailus D, Moksa M, Chittaranjan S, Rimsza L,
1774:
Lohr JG, Stojanov P, Lawrence MS, Auclair D, Chapuy B, Sougnez C, Cruz-Gordillo P, Knoechel B, Asmann YW, Slager SL, Novak AJ, Dogan A, Ansell SM, Link BK, Zou L, Gould J, Saksena G, Stransky N, Rangel-Escareño C, Fernandez-Lopez JC, Hidalgo-Miranda A, Melendez-Zajgla J, Hernández-Lemus E,
2226:
Carfí A, Gong H, Lou H, Willis SH, Cohen GH, Eisenberg RJ, Wiley DC (May 2002). "Crystallization and preliminary diffraction studies of the ectodomain of the envelope glycoprotein D from herpes simplex virus 1 alone and in complex with the ectodomain of the human receptor HveA".
62: 1717:
Brooks-Wilson A, Spinelli JJ, Ben-Neriah S, Meissner B, Woolcock B, Boyle M, McDonald H, Tam A, Zhao Y, Delaney A, Zeng T, Tse K, Butterfield Y, Birol I, Holt R, Schein J, Horsman DE, Moore R, Jones SJ, Connors JM, Hirst M, Gascoyne RD, Marra MA (August 2011).
2422:
Krummenacher C, Baribaud F, Ponce de Leon M, Baribaud I, Whitbeck JC, Xu R, Cohen GH, Eisenberg RJ (May 2004). "Comparative usage of herpesvirus entry mediator A and nectin-1 by laboratory strains and clinical isolates of herpes simplex virus".
1911:"Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1" 1587:"Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1" 2494: 3781: 3140: 3565: 1834:
Koo M, Ohgami RS (May 2017). "Pediatric-type Follicular Lymphoma and Pediatric Nodal Marginal Zone Lymphoma: Recent Clinical, Morphologic, Immunophenotypic, and Genetic Insights".
334: 233: 3797: 1497:
Hoek KS, Schlegel NC, Eichhoff OM, Widmer DS, Praetorius C, Einarsson SO, Valgeirsdottir S, Bergsteinsdottir K, Schepsky A, Dummer R, Steingrimsson E (December 2008).
4259: 3725: 3263: 1204: 3847: 4279: 2550: 1775:
Schwarz-Cruz y Celis A, Imaz-Rosshandler I, Ojesina AI, Jung J, Pedamallu CS, Lander ES, Habermann TM, Cerhan JR, Shipp MA, Getz G, Golub TR (March 2012).
4627: 3907: 3558: 850: 1398:
Kwon BS, Tan KB, Ni J, Oh KO, Lee ZH, Kim KK, Kim YJ, Wang S, Gentz R, Yu GL, Harrop J, Lyn SD, Silverman C, Porter TG, Truneh A, Young PR (May 1997).
831: 156: 2940: 1400:"A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation" 4250: 4239: 4215: 3705: 3511: 1196:
The protein encoded by this gene is a member of the TNF-receptor superfamily. The cytoplasmic region of this receptor was found to bind to several
3229: 3225: 3208: 1254:(HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. 3594: 3342: 3317: 3181: 1331: 3741: 3551: 3346: 3321: 3172: 2474: 2022:
Kelly K, Manos E, Jensen G, Nadauld L, Jones DA (February 2000). "APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death".
1481: 1944:
Mauri DN, Ebner R, Montgomery RI, Kochel KD, Cheung TC, Yu GL, Ruben S, Murphy M, Eisenberg RJ, Cohen GH, Spear PG, Ware CF (January 1998).
1313: 4647: 3873: 3499: 3198: 3133: 2509: 3193: 320: 3605: 1244: 1069: 4559: 1062: 297: 3072: 2777: 2769: 2543: 2193:"Search for polymorphisms in the genes for herpesvirus entry mediator, nectin-1, and nectin-2 in immune seronegative individuals" 1446: 127:, ATAR, CD270, HVEA, HVEM, LIGHTR, TR2, tumor necrosis factor receptor superfamily member 14, TNF receptor superfamily member 14 3420: 2718: 1300: 1279: 4270: 3972: 3415: 3363: 2754: 2158:"Tumor necrosis factor receptor and ligand superfamily family members TNFRSF14 and LIGHT: new players in human atherogenesis" 1197: 1296: 219: 194: 59: 2667: 2629: 2624: 1275: 1240: 2377:
Jung HW, La SJ, Kim JY, Heo SK, Kim JY, Wang S, Kim KK, Lee KM, Cho HR, Lee HW, Kwon B, Kim BS, Kwon BS (December 2003).
2043:
Zhang J, Salcedo TW, Wan X, Ullrich S, Hu B, Gregorio T, Feng P, Qi S, Chen H, Cho YH, Li Y, Moore PA, Wu J (June 2001).
1626:
Zhang J, Salcedo TW, Wan X, Ullrich S, Hu B, Gregorio T, Feng P, Qi S, Chen H, Cho YH, Li Y, Moore PA, Wu J (June 2001).
4652: 4574: 2672: 333: 232: 136: 3384: 3380: 2536: 1777:"Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing" 1216: 3085: 326: 225: 4564: 4206: 3400: 3016: 2572: 1677:"A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis" 1177: 4165: 3635: 3376: 3300: 2999: 2785: 2467: 2258:"Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptor" 3530: 3494: 3025: 899: 144: 2379:"High levels of soluble herpes virus entry mediator in sera of patients with allergic and autoimmune diseases" 1946:"LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator" 1200:(TRAF) family members, which may mediate the signal transduction pathways that activate the immune response. 3918: 3614: 3449: 3427: 3351: 3338: 3325: 3313: 3281: 3268: 3258: 3234: 3221: 3177: 3168: 3095: 3068: 3059: 2654: 880: 876: 3630: 4303: 3486: 3410: 3163: 3129: 3120: 3090: 3081: 3064: 2662: 2582: 4115: 4110: 4061: 3188: 2293:"Differential expression of LIGHT and its receptors in human placental villi and amniochorion membranes" 2088:"The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases" 1137: 3700: 2503:: CRYSTAL STRUCTURE OF THE HERPES SIMPLEX VIRUS GLYCOPROTEIN D BOUND TO THE CELLULAR RECEPTOR HVEA/HVEM 3715: 4230: 4066: 3771: 3665: 3308: 3216: 3158: 3115: 3042: 2460: 1788: 1730: 1251: 208: 123: 4473: 4181: 4071: 3963: 3680: 3675: 3670: 3660: 3525: 3520: 3358: 1351:"Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family" 1020: 969: 3934: 3792: 3761: 4095: 4090: 4056: 4051: 3997: 3812: 3585: 3577: 3515: 3286: 3034: 2567: 1380: 168: 20: 4584: 3888: 3878: 3868: 3802: 3751: 1045: 1024: 994: 973: 4513: 4503: 4493: 4430: 4155: 3858: 2121:
Carfí A, Willis SH, Whitbeck JC, Krummenacher C, Cohen GH, Eisenberg RJ, Wiley DC (July 2001).
1453:. National Library of Medicine, National Center for Biotechnology Information. 23 November 2023 571: 4523: 4508: 4425: 4390: 4135: 3640: 3574: 2559: 2440: 2410: 2365: 2322: 2279: 2244: 2214: 2179: 2144: 2109: 2074: 2031: 2010: 1967: 1932: 1897: 1851: 1816: 1756: 1698: 1657: 1608: 1564: 1520: 1477: 1421: 1372: 164: 116: 52: 4450: 3625: 1981:"Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2" 1876:"ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5" 1543:"ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5" 4176: 4105: 4100: 3988: 3645: 3474: 3277: 3150: 2991: 2983: 2884: 2876: 2868: 2860: 2432: 2400: 2390: 2355: 2347: 2312: 2304: 2269: 2236: 2204: 2169: 2134: 2099: 2064: 2056: 2000: 1992: 1957: 1922: 1887: 1843: 1806: 1796: 1746: 1738: 1688: 1647: 1639: 1598: 1554: 1510: 1472:
Ware, Carl (2008). "Chapter 25: TNF-Related Cytokines in Immunity". In Paul, William (ed.).
1411: 1362: 413: 344: 288: 243: 4084: 2336:"Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry" 1172:
are structurally unrelated proteins of the immunoglobulin superfamily. It is also known as
35: 4554: 4531: 4076: 3993: 3756: 2900: 1476:(Book) (6th ed.). Philadelphia: Lippincott Williams & Wilkins. pp. 776–801. 388: 2334:
Bender FC, Whitbeck JC, Ponce de Leon M, Lou H, Eisenberg RJ, Cohen GH (September 2003).
1792: 1734: 4415: 4405: 4332: 3949: 3939: 3863: 3695: 2801: 2317: 2292: 1811: 1776: 1751: 1718: 2360: 2335: 2308: 2139: 2122: 2069: 2044: 2005: 1980: 1962: 1945: 1652: 1627: 1367: 1350: 765: 760: 755: 750: 745: 740: 735: 730: 725: 720: 715: 710: 705: 700: 695: 690: 685: 669: 664: 659: 654: 649: 633: 628: 623: 618: 613: 4641: 4631: 3983: 3766: 3685: 3253: 3047: 2351: 1515: 1498: 600: 1384: 148: 4589: 4569: 4488: 4478: 4420: 4367: 4297: 4196: 4140: 3827: 3817: 3807: 3710: 3690: 3655: 3650: 3441: 2809: 1141: 406: 185: 2191:
Struyf F, Posavad CM, Keyaerts E, Van Ranst M, Corey L, Spear PG (January 2002).
1847: 172: 4599: 4594: 4498: 4483: 4455: 4445: 4440: 4395: 4362: 4357: 4352: 4347: 4342: 4327: 4322: 4145: 4130: 4125: 3944: 3929: 3746: 2634: 2609: 2436: 1336:
National Center for Biotechnology Information, U.S. National Library of Medicine
1318:
National Center for Biotechnology Information, U.S. National Library of Medicine
3543: 1781:
Proceedings of the National Academy of Sciences of the United States of America
489: 4435: 4337: 4191: 3736: 2240: 1447:"TNFRSF14 TNF receptor superfamily member 14 [ Homo sapiens (human) ]" 305: 202: 152: 1927: 1910: 1909:
Marsters SA, Ayres TM, Skubatch M, Gray CL, Rothe M, Ashkenazi A (May 1997).
1892: 1875: 1693: 1676: 1603: 1586: 1585:
Marsters SA, Ayres TM, Skubatch M, Gray CL, Rothe M, Ashkenazi A (May 1997).
1559: 1542: 1416: 1399: 4609: 4604: 4385: 3832: 2924: 2916: 2908: 2174: 2157: 1801: 1276:
ENSG00000157873 GRCh38: Ensembl release 89: ENSG00000273936, ENSG00000157873
795: 549: 427: 372: 359: 271: 258: 160: 2444: 2414: 2369: 2326: 2283: 2274: 2257: 2248: 2218: 2183: 2148: 2113: 2104: 2087: 2078: 2035: 1996: 1855: 1820: 1760: 1702: 1661: 1524: 2014: 1971: 1936: 1901: 1874:
Hsu H, Solovyev I, Colombero A, Elliott R, Kelley M, Boyle WJ (May 1997).
1612: 1568: 1541:
Hsu H, Solovyev I, Colombero A, Elliott R, Kelley M, Boyle WJ (May 1997).
1425: 1376: 1109: 1104: 3837: 2964: 2956: 2948: 2932: 1239:
Mutations in this gene have been recurrently been associated to cases of
1093: 944: 925: 2395: 2378: 1742: 1499:"Novel MITF targets identified using a two-step DNA microarray strategy" 3333: 3329: 3076: 1224: 911: 862: 2405: 2123:"Herpes simplex virus glycoprotein D bound to the human receptor HveA" 1719:"Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma" 93: 89: 85: 81: 4410: 4400: 4045: 4041: 4037: 4033: 4029: 4025: 3469: 3464: 3459: 3454: 3431: 3371: 3367: 3107: 2740: 2528: 2060: 1643: 1077: 817: 2209: 2192: 4080: 4021: 4017: 4013: 4009: 4005: 4001: 3898: 3504: 3124: 3055: 3051: 2841: 2793: 2735: 2699: 2694: 2689: 2684: 2679: 2644: 2604: 2594: 1228: 1220: 1203:
In melanocytic cells TNFRSF14 gene expression may be regulated by
780: 776: 4465: 4377: 4314: 2892: 2833: 2825: 2817: 2728: 2639: 2619: 2614: 2599: 2590: 1169: 1165: 140: 3547: 2532: 2456: 2256:
Hu YC, Shyr CR, Che W, Mu XM, Kim E, Chang C (September 2002).
580: 2452: 2045:"Modulation of T-cell responses to alloantigens by TR6/DcR3" 1628:"Modulation of T-cell responses to alloantigens by TR6/DcR3" 1349:
Montgomery RI, Warner MS, Lum BJ, Spear PG (November 1996).
1675:
Yu KY, Kwon B, Ni J, Zhai Y, Ebner R, Kwon BS (May 1999).
751:
positive regulation of peptidyl-tyrosine phosphorylation
396: 3706:
Methoxy polyethylene glycol-epoetin beta (CERA/Mircera)
1250:
This receptor was identified as a cellular mediator of
746:
negative regulation of alpha-beta T cell proliferation
19:"HveA" redirects here. For Harbourview Estates A, see 2086:
Franco PJ, Farooqui M, Seto E, Wei LN (August 2001).
561: 1180:
classification. Moreover, it is also referred to as
1130:
tumor necrosis factor receptor superfamily member 14
4544: 4522: 4464: 4376: 4313: 4296: 4289: 4269: 4249: 4229: 4205: 4164: 3971: 3962: 3917: 3897: 3846: 3780: 3724: 3613: 3604: 3584: 3485: 3440: 3399: 3299: 3245: 3207: 3149: 3106: 3033: 3024: 3015: 2976: 2853: 2762: 2753: 2708: 2653: 2581: 2566: 1038: 1013: 987: 962: 2518:: Crystal structure of the human BTLA-HVEM complex 2162:Arteriosclerosis, Thrombosis, and Vascular Biology 1292: 1290: 1288: 1271: 1269: 1267: 624:tumor necrosis factor-activated receptor activity 343: 242: 3798:Granulocyte macrophage colony-stimulating factor 696:tumor necrosis factor-mediated signaling pathway 16:Protein-coding gene in the species Homo sapiens 1979:Lee CH, Chinpaisal C, Wei LN (November 1998). 1580: 1578: 1536: 1534: 1297:GRCm38: Ensembl release 89: ENSMUSG00000042333 3559: 2544: 2468: 8: 761:defense response to Gram-positive bacterium 756:defense response to Gram-negative bacterium 716:regulation of cell population proliferation 4628:United States National Library of Medicine 4565:Leukemia/leukocyte inhibitory factor (LIF) 4310: 4293: 3968: 3610: 3566: 3552: 3544: 3030: 3021: 2759: 2578: 2551: 2537: 2529: 2475: 2461: 2453: 791: 596: 384: 283: 180: 70: 4560:FMS-like tyrosine kinase 3 ligand (FLT3L) 3989:Interferon alpha (interferon alfa, IFN-α) 2404: 2394: 2359: 2316: 2273: 2208: 2173: 2138: 2103: 2068: 2004: 1961: 1926: 1891: 1810: 1800: 1750: 1692: 1651: 1602: 1558: 1514: 1415: 1366: 4626:This article incorporates text from the 4582:Additional cytokine receptor modulators: 2291:Gill RM, Ni J, Hunt JS (December 2002). 1441: 1439: 1437: 1435: 2490: 1263: 766:positive regulation of T cell migration 706:cell surface receptor signaling pathway 4406:Cucurbitacin I (elatericin B, JSI-124) 25: 3742:Granulocyte colony-stimulating factor 2383:Experimental & Molecular Medicine 2156:Bobik A, Kalinina N (December 2001). 2049:The Journal of Clinical Investigation 1632:The Journal of Clinical Investigation 1156:This protein was originally known as 665:integral component of plasma membrane 348: 309: 304: 247: 206: 201: 7: 4101:Interferon kappa (IFN-ε/κ/τ/ζ, IFNK) 3874:Macrophage colony-stimulating factor 1503:Pigment Cell & Melanoma Research 4575:Thymic stromal lymphopoietin (TSLP) 2262:The Journal of Biological Chemistry 1915:The Journal of Biological Chemistry 1880:The Journal of Biological Chemistry 1681:The Journal of Biological Chemistry 1591:The Journal of Biological Chemistry 1547:The Journal of Biological Chemistry 1404:The Journal of Biological Chemistry 2197:The Journal of Infectious Diseases 1245:pediatric-type follicular lymphoma 1035: 1010: 984: 959: 935: 916: 890: 867: 841: 822: 701:multicellular organism development 566: 484: 422: 401: 14: 2297:The American Journal of Pathology 2508: 2493: 2352:10.1128/JVI.77.17.9542-9552.2003 2229:Acta Crystallographica Section D 1516:10.1111/j.1755-148X.2008.00505.x 1186:another TRAF-associated receptor 670:external side of plasma membrane 629:ubiquitin protein ligase binding 570: 332: 325: 319: 296: 231: 224: 218: 193: 34: 4106:Interferon omega (IFN-ω, IFNW1) 686:regulation of apoptotic process 1985:Molecular and Cellular Biology 1836:Advances in Anatomic Pathology 1198:TNF receptor associated factor 711:response to lipopolysaccharide 650:integral component of membrane 581:More reference expression data 550:More reference expression data 1: 2309:10.1016/S0002-9440(10)64479-3 2140:10.1016/S1097-2765(01)00298-2 1963:10.1016/S1074-7613(00)80455-0 1368:10.1016/S0092-8674(00)81363-X 1241:diffuse large B-cell lymphoma 317: 216: 1848:10.1097/PAP.0000000000000144 1158:herpesvirus entry mediator A 4648:Genes on human chromosome 1 3950:Thrombopoietin (THPO, MGDF) 3716:Pegol sihematide (EPO-018B) 3636:Carbamylated erythropoietin 2437:10.1016/j.virol.2004.02.005 1215:TNFRSF14 has been shown to 1144:superfamily encoded by the 726:apoptotic signaling pathway 4669: 1178:cluster of differentiation 1122:Herpesvirus entry mediator 731:viral entry into host cell 458:mucosa of transverse colon 18: 4499:Tofacitinib (tasocitinib) 4456:Tofacitinib (tasocitinib) 4363:Tofacitinib (tasocitinib) 2488: 2241:10.1107/S0907444902001270 1332:"Mouse PubMed Reference:" 1314:"Human PubMed Reference:" 1108: 1103: 1099: 1092: 1076: 1070:Chr 4: 155.01 – 155.01 Mb 1057: 1042: 1017: 1006: 991: 966: 955: 942: 938: 923: 919: 910: 897: 893: 874: 870: 861: 848: 844: 829: 825: 816: 801: 794: 790: 774: 599: 595: 578: 569: 560: 547: 496: 487: 434: 425: 395: 387: 383: 366: 353: 316: 295: 286: 282: 265: 252: 215: 192: 183: 179: 134: 131: 121: 114: 109: 78: 73: 56: 51: 46: 42: 33: 28: 4177:Interferon gamma (IFN-γ) 1928:10.1074/jbc.272.22.14029 1893:10.1074/jbc.272.21.13471 1694:10.1074/jbc.274.20.13733 1604:10.1074/jbc.272.22.14029 1560:10.1074/jbc.272.21.13471 1417:10.1074/jbc.272.22.14272 4077:Interferon beta (IFN-β) 2175:10.1161/atvb.21.12.1873 2092:Molecular Endocrinology 1802:10.1073/pnas.1121343109 614:virus receptor activity 4555:Cardiotrophin 1 (CT-1) 3487:Enzyme-linked receptor 2275:10.1074/jbc.M203531200 2105:10.1210/mend.15.8.0682 1997:10.1128/mcb.18.11.6745 1474:Fundamental Immunology 4552:Additional cytokines: 4479:Decernotinib (VX-509) 4116:Peginterferon alfa-2b 4111:Peginterferon alfa-2a 3631:Asialo erythropoietin 3309:Interleukin receptors 3217:Interleukin receptors 3159:Interleukin receptors 3116:Interleukin receptors 3043:Interleukin receptors 1138:cell surface receptor 1063:Chr 1: 2.56 – 2.57 Mb 736:inflammatory response 4067:Interferon alfacon-1 3696:Erythropoietin (EPO) 3359:Interferon receptors 1252:herpes simplex virus 691:T cell costimulation 462:right adrenal cortex 311:Chromosome 4 (mouse) 209:Chromosome 1 (human) 173:TNFRSF14 - orthologs 74:List of PDB id codes 47:Available structures 4653:TNF receptor family 4214:See IL-28R (IFNLR) 4182:Interferon gamma 1b 4072:Interferon alpha-n3 2396:10.1038/emm.2003.65 2340:Journal of Virology 1793:2012PNAS..109.3879L 1743:10.1038/nature10351 1735:2011Natur.476..298M 466:canal of the cervix 4630:, which is in the 4570:Oncostatin M (OSM) 4096:Interferon beta 1b 4091:Interferon beta 1a 4062:Interferon alfa n1 4057:Interferon alfa 2b 4052:Interferon alfa 2a 3886:Kinase inhibitors: 2568:Chemokine receptor 2560:Cytokine receptors 1235:Clinical relevance 900:ENSMUSG00000042333 679:Biological process 643:Cellular component 607:Molecular function 446:right uterine tube 21:CityPlace, Toronto 4622: 4621: 4618: 4617: 4540: 4539: 4307: 4225: 4224: 3958: 3957: 3701:Erythropoietin-Fc 3575:Cytokine receptor 3541: 3540: 3395: 3394: 3295: 3294: 3011: 3010: 2749: 2748: 2526: 2525: 1729:(7360): 298–303. 1483:978-0-7817-6519-0 1128:), also known as 1119: 1118: 1115: 1114: 1088: 1087: 1053: 1052: 1032: 1031: 1002: 1001: 981: 980: 951: 950: 932: 931: 906: 905: 887: 886: 857: 856: 838: 837: 786: 785: 591: 590: 587: 586: 556: 555: 543: 542: 481: 480: 379: 378: 278: 277: 105: 104: 101: 100: 57:Ortholog search: 4660: 4311: 4301: 4294: 4153:Decoy receptors: 3969: 3646:Darbepoetin alfa 3611: 3568: 3561: 3554: 3545: 3278:hormone receptor 3031: 3022: 2760: 2579: 2553: 2546: 2539: 2530: 2512: 2497: 2477: 2470: 2463: 2454: 2448: 2418: 2408: 2398: 2373: 2363: 2330: 2320: 2287: 2277: 2252: 2222: 2212: 2187: 2177: 2152: 2142: 2117: 2107: 2082: 2072: 2061:10.1172/JCI12159 2039: 2018: 2008: 1975: 1965: 1940: 1930: 1921:(22): 14029–32. 1905: 1895: 1860: 1859: 1831: 1825: 1824: 1814: 1804: 1771: 1765: 1764: 1754: 1713: 1707: 1706: 1696: 1672: 1666: 1665: 1655: 1644:10.1172/JCI12159 1623: 1617: 1616: 1606: 1597:(22): 14029–32. 1582: 1573: 1572: 1562: 1538: 1529: 1528: 1518: 1494: 1488: 1487: 1469: 1463: 1462: 1460: 1458: 1443: 1430: 1429: 1419: 1395: 1389: 1388: 1370: 1346: 1340: 1339: 1328: 1322: 1321: 1310: 1304: 1294: 1283: 1273: 1101: 1100: 1072: 1065: 1048: 1036: 1027: 1011: 1007:RefSeq (protein) 997: 985: 976: 960: 936: 917: 891: 868: 842: 823: 792: 634:cytokine binding 597: 583: 574: 567: 552: 492: 490:Top expressed in 485: 454:transverse colon 430: 428:Top expressed in 423: 402: 385: 375: 362: 351: 336: 329: 323: 312: 300: 284: 274: 261: 250: 235: 228: 222: 211: 197: 181: 175: 126: 119: 96: 71: 65: 44: 43: 38: 26: 4668: 4667: 4663: 4662: 4661: 4659: 4658: 4657: 4638: 4637: 4623: 4614: 4536: 4532:Deucravacitinib 4518: 4460: 4372: 4300: 4285: 4265: 4245: 4221: 4201: 4160: 3994:Interferon alfa 3954: 3913: 3893: 3842: 3776: 3772:Pegnartograstim 3757:Lipegfilgrastim 3720: 3666:Epoetin epsilon 3600: 3580: 3572: 3542: 3537: 3481: 3436: 3391: 3291: 3241: 3203: 3145: 3102: 3007: 2972: 2901:Osteoprotegerin 2849: 2745: 2704: 2649: 2570: 2562: 2557: 2527: 2522: 2519: 2513: 2504: 2498: 2484: 2481: 2451: 2421: 2376: 2346:(17): 9542–52. 2333: 2290: 2268:(37): 33571–9. 2255: 2235:(Pt 5): 836–8. 2225: 2190: 2155: 2120: 2085: 2055:(11): 1459–68. 2042: 2024:Cancer Research 2021: 1991:(11): 6745–55. 1978: 1943: 1908: 1886:(21): 13471–4. 1873: 1869: 1867:Further reading 1864: 1863: 1833: 1832: 1828: 1787:(10): 3879–84. 1773: 1772: 1768: 1715: 1714: 1710: 1687:(20): 13733–6. 1674: 1673: 1669: 1638:(11): 1459–68. 1625: 1624: 1620: 1584: 1583: 1576: 1553:(21): 13471–4. 1540: 1539: 1532: 1496: 1495: 1491: 1484: 1471: 1470: 1466: 1456: 1454: 1445: 1444: 1433: 1410:(22): 14272–6. 1397: 1396: 1392: 1348: 1347: 1343: 1330: 1329: 1325: 1312: 1311: 1307: 1295: 1286: 1274: 1265: 1260: 1237: 1213: 1194: 1154: 1110:View/Edit Mouse 1105:View/Edit Human 1068: 1061: 1058:Location (UCSC) 1044: 1023: 1019: 993: 972: 968: 881:ENSG00000157873 879: 877:ENSG00000273936 770: 721:immune response 674: 660:plasma membrane 638: 619:protein binding 579: 548: 539: 534: 530: 526: 522: 518: 516:muscle of thigh 514: 510: 506: 502: 488: 477: 472: 468: 464: 460: 456: 452: 448: 444: 440: 426: 370: 357: 349: 339: 338: 337: 330: 310: 287:Gene location ( 269: 256: 248: 238: 237: 236: 229: 207: 184:Gene location ( 135: 122: 115: 80: 58: 24: 17: 12: 11: 5: 4666: 4664: 4656: 4655: 4650: 4640: 4639: 4620: 4619: 4616: 4615: 4613: 4612: 4607: 4602: 4597: 4592: 4587: 4578: 4577: 4572: 4567: 4562: 4557: 4548: 4546: 4542: 4541: 4538: 4537: 4535: 4534: 4528: 4526: 4520: 4519: 4517: 4516: 4511: 4506: 4501: 4496: 4491: 4486: 4481: 4476: 4474:Cercosporamide 4470: 4468: 4462: 4461: 4459: 4458: 4453: 4448: 4443: 4438: 4433: 4428: 4423: 4418: 4416:Deuruxolitinib 4413: 4408: 4403: 4398: 4393: 4388: 4382: 4380: 4374: 4373: 4371: 4370: 4365: 4360: 4355: 4350: 4345: 4340: 4335: 4333:Deuruxolitinib 4330: 4325: 4319: 4317: 4308: 4291: 4287: 4286: 4284: 4283: 4275: 4273: 4267: 4266: 4264: 4263: 4255: 4253: 4247: 4246: 4244: 4243: 4235: 4233: 4227: 4226: 4223: 4222: 4220: 4219: 4211: 4209: 4207:IFNLR (λ, III) 4203: 4202: 4200: 4199: 4194: 4185: 4184: 4179: 4170: 4168: 4162: 4161: 4159: 4158: 4149: 4148: 4143: 4138: 4133: 4128: 4119: 4118: 4113: 4108: 4103: 4098: 4093: 4088: 4074: 4069: 4064: 4059: 4054: 4049: 3991: 3986: 3977: 3975: 3973:IFNAR (α/β, I) 3966: 3960: 3959: 3956: 3955: 3953: 3952: 3947: 3942: 3940:Promegapoietin 3937: 3932: 3923: 3921: 3919:Thrombopoietin 3915: 3914: 3912: 3911: 3903: 3901: 3895: 3894: 3892: 3891: 3882: 3881: 3876: 3871: 3866: 3864:Interleukin-34 3861: 3852: 3850: 3844: 3843: 3841: 3840: 3835: 3830: 3821: 3820: 3815: 3810: 3805: 3800: 3795: 3786: 3784: 3778: 3777: 3775: 3774: 3769: 3764: 3759: 3754: 3749: 3744: 3739: 3730: 3728: 3722: 3721: 3719: 3718: 3713: 3708: 3703: 3698: 3693: 3688: 3683: 3678: 3673: 3668: 3663: 3658: 3653: 3648: 3643: 3638: 3633: 3628: 3619: 3617: 3615:Erythropoietin 3608: 3602: 3601: 3599: 3598: 3590: 3588: 3582: 3581: 3573: 3571: 3570: 3563: 3556: 3548: 3539: 3538: 3536: 3535: 3534: 3533: 3528: 3523: 3509: 3508: 3507: 3502: 3491: 3489: 3483: 3482: 3480: 3479: 3478: 3477: 3472: 3467: 3462: 3457: 3446: 3444: 3438: 3437: 3435: 3434: 3425: 3424: 3423: 3418: 3408: 3405: 3403: 3401:Ig superfamily 3397: 3396: 3393: 3392: 3390: 3389: 3388: 3387: 3374: 3356: 3355: 3354: 3349: 3336: 3305: 3303: 3297: 3296: 3293: 3292: 3290: 3289: 3284: 3274: 3273: 3272: 3271: 3269:Thrombopoietin 3266: 3261: 3249: 3247: 3243: 3242: 3240: 3239: 3238: 3237: 3232: 3213: 3211: 3205: 3204: 3202: 3201: 3196: 3191: 3186: 3185: 3184: 3175: 3166: 3155: 3153: 3147: 3146: 3144: 3143: 3138: 3137: 3136: 3127: 3112: 3110: 3104: 3103: 3101: 3100: 3099: 3098: 3093: 3088: 3079: 3062: 3039: 3037: 3028: 3019: 3013: 3012: 3009: 3008: 3006: 3005: 2997: 2989: 2980: 2978: 2974: 2973: 2971: 2970: 2962: 2954: 2946: 2938: 2930: 2922: 2914: 2906: 2898: 2890: 2882: 2874: 2866: 2857: 2855: 2851: 2850: 2848: 2847: 2839: 2831: 2823: 2815: 2807: 2799: 2791: 2783: 2775: 2766: 2764: 2757: 2751: 2750: 2747: 2746: 2744: 2743: 2738: 2733: 2732: 2731: 2723: 2722: 2721: 2712: 2710: 2706: 2705: 2703: 2702: 2697: 2692: 2687: 2682: 2677: 2676: 2675: 2670: 2659: 2657: 2651: 2650: 2648: 2647: 2642: 2637: 2632: 2627: 2622: 2617: 2612: 2607: 2602: 2597: 2587: 2585: 2576: 2564: 2563: 2558: 2556: 2555: 2548: 2541: 2533: 2524: 2523: 2521: 2520: 2514: 2507: 2505: 2499: 2492: 2489: 2486: 2485: 2482: 2480: 2479: 2472: 2465: 2457: 2450: 2449: 2419: 2374: 2331: 2288: 2253: 2223: 2210:10.1086/338116 2188: 2168:(12): 1873–5. 2153: 2127:Molecular Cell 2118: 2098:(8): 1318–28. 2083: 2040: 2019: 1976: 1941: 1906: 1870: 1868: 1865: 1862: 1861: 1842:(3): 128–135. 1826: 1766: 1708: 1667: 1618: 1574: 1530: 1489: 1482: 1464: 1431: 1390: 1341: 1323: 1305: 1284: 1262: 1261: 1259: 1256: 1236: 1233: 1212: 1209: 1193: 1190: 1153: 1150: 1136:), is a human 1117: 1116: 1113: 1112: 1107: 1097: 1096: 1090: 1089: 1086: 1085: 1083: 1081: 1074: 1073: 1066: 1059: 1055: 1054: 1051: 1050: 1040: 1039: 1033: 1030: 1029: 1015: 1014: 1008: 1004: 1003: 1000: 999: 989: 988: 982: 979: 978: 964: 963: 957: 953: 952: 949: 948: 940: 939: 933: 930: 929: 921: 920: 914: 908: 907: 904: 903: 895: 894: 888: 885: 884: 872: 871: 865: 859: 858: 855: 854: 846: 845: 839: 836: 835: 827: 826: 820: 814: 813: 808: 803: 799: 798: 788: 787: 784: 783: 772: 771: 769: 768: 763: 758: 753: 748: 743: 738: 733: 728: 723: 718: 713: 708: 703: 698: 693: 688: 682: 680: 676: 675: 673: 672: 667: 662: 657: 652: 646: 644: 640: 639: 637: 636: 631: 626: 621: 616: 610: 608: 604: 603: 593: 592: 589: 588: 585: 584: 576: 575: 564: 558: 557: 554: 553: 545: 544: 541: 540: 538: 537: 533: 529: 525: 521: 517: 513: 509: 505: 501: 497: 494: 493: 482: 479: 478: 476: 475: 474:gastric mucosa 471: 467: 463: 459: 455: 451: 447: 443: 439: 435: 432: 431: 419: 418: 410: 399: 393: 392: 389:RNA expression 381: 380: 377: 376: 368: 364: 363: 355: 352: 347: 341: 340: 331: 324: 318: 314: 313: 308: 302: 301: 293: 292: 280: 279: 276: 275: 267: 263: 262: 254: 251: 246: 240: 239: 230: 223: 217: 213: 212: 205: 199: 198: 190: 189: 177: 176: 133: 129: 128: 120: 112: 111: 107: 106: 103: 102: 99: 98: 76: 75: 67: 66: 55: 49: 48: 40: 39: 31: 30: 15: 13: 10: 9: 6: 4: 3: 2: 4665: 4654: 4651: 4649: 4646: 4645: 4643: 4636: 4635: 4633: 4632:public domain 4629: 4611: 4608: 4606: 4603: 4601: 4598: 4596: 4593: 4591: 4588: 4586: 4583: 4580: 4579: 4576: 4573: 4571: 4568: 4566: 4563: 4561: 4558: 4556: 4553: 4550: 4549: 4547: 4543: 4533: 4530: 4529: 4527: 4525: 4521: 4515: 4512: 4510: 4507: 4505: 4502: 4500: 4497: 4495: 4492: 4490: 4487: 4485: 4482: 4480: 4477: 4475: 4472: 4471: 4469: 4467: 4463: 4457: 4454: 4452: 4449: 4447: 4444: 4442: 4439: 4437: 4434: 4432: 4429: 4427: 4424: 4422: 4419: 4417: 4414: 4412: 4409: 4407: 4404: 4402: 4399: 4397: 4394: 4392: 4389: 4387: 4384: 4383: 4381: 4379: 4375: 4369: 4366: 4364: 4361: 4359: 4356: 4354: 4351: 4349: 4346: 4344: 4341: 4339: 4336: 4334: 4331: 4329: 4326: 4324: 4321: 4320: 4318: 4316: 4312: 4309: 4305: 4299: 4295: 4292: 4288: 4281: 4277: 4276: 4274: 4272: 4268: 4261: 4257: 4256: 4254: 4252: 4248: 4241: 4237: 4236: 4234: 4232: 4228: 4217: 4213: 4212: 4210: 4208: 4204: 4198: 4195: 4193: 4190: 4187: 4186: 4183: 4180: 4178: 4175: 4172: 4171: 4169: 4167: 4166:IFNGR (γ, II) 4163: 4157: 4154: 4151: 4150: 4147: 4144: 4142: 4139: 4137: 4134: 4132: 4129: 4127: 4124: 4121: 4120: 4117: 4114: 4112: 4109: 4107: 4104: 4102: 4099: 4097: 4094: 4092: 4089: 4086: 4082: 4078: 4075: 4073: 4070: 4068: 4065: 4063: 4060: 4058: 4055: 4053: 4050: 4047: 4043: 4039: 4035: 4031: 4027: 4023: 4019: 4015: 4011: 4007: 4003: 3999: 3995: 3992: 3990: 3987: 3985: 3984:Albinterferon 3982: 3979: 3978: 3976: 3974: 3970: 3967: 3965: 3961: 3951: 3948: 3946: 3943: 3941: 3938: 3936: 3933: 3931: 3928: 3925: 3924: 3922: 3920: 3916: 3909: 3905: 3904: 3902: 3900: 3896: 3890: 3887: 3884: 3883: 3880: 3877: 3875: 3872: 3870: 3867: 3865: 3862: 3860: 3857: 3854: 3853: 3851: 3849: 3845: 3839: 3836: 3834: 3831: 3829: 3826: 3823: 3822: 3819: 3816: 3814: 3811: 3809: 3806: 3804: 3801: 3799: 3796: 3794: 3791: 3788: 3787: 3785: 3783: 3782:GM-CSF (CSF2) 3779: 3773: 3770: 3768: 3767:Pegfilgrastim 3765: 3763: 3760: 3758: 3755: 3753: 3750: 3748: 3745: 3743: 3740: 3738: 3735: 3732: 3731: 3729: 3727: 3723: 3717: 3714: 3712: 3709: 3707: 3704: 3702: 3699: 3697: 3694: 3692: 3689: 3687: 3686:Epoetin theta 3684: 3682: 3681:Epoetin omega 3679: 3677: 3676:Epoetin kappa 3674: 3672: 3671:Epoetin gamma 3669: 3667: 3664: 3662: 3661:Epoetin delta 3659: 3657: 3654: 3652: 3649: 3647: 3644: 3642: 3639: 3637: 3634: 3632: 3629: 3627: 3624: 3621: 3620: 3618: 3616: 3612: 3609: 3607: 3603: 3596: 3592: 3591: 3589: 3587: 3583: 3579: 3576: 3569: 3564: 3562: 3557: 3555: 3550: 3549: 3546: 3532: 3529: 3527: 3524: 3522: 3519: 3518: 3517: 3513: 3510: 3506: 3503: 3501: 3498: 3497: 3496: 3493: 3492: 3490: 3488: 3484: 3476: 3473: 3471: 3468: 3466: 3463: 3461: 3458: 3456: 3453: 3452: 3451: 3448: 3447: 3445: 3443: 3439: 3433: 3429: 3426: 3422: 3419: 3417: 3414: 3413: 3412: 3409: 3407: 3406: 3404: 3402: 3398: 3386: 3382: 3378: 3375: 3373: 3369: 3365: 3362: 3361: 3360: 3357: 3353: 3350: 3348: 3344: 3340: 3337: 3335: 3331: 3327: 3323: 3319: 3315: 3312: 3311: 3310: 3307: 3306: 3304: 3302: 3298: 3288: 3285: 3283: 3279: 3276: 3275: 3270: 3267: 3265: 3262: 3260: 3257: 3256: 3255: 3254:CSF receptors 3251: 3250: 3248: 3244: 3236: 3233: 3231: 3227: 3223: 3220: 3219: 3218: 3215: 3214: 3212: 3210: 3206: 3200: 3197: 3195: 3192: 3190: 3187: 3183: 3179: 3176: 3174: 3170: 3167: 3165: 3162: 3161: 3160: 3157: 3156: 3154: 3152: 3148: 3142: 3139: 3135: 3131: 3128: 3126: 3122: 3119: 3118: 3117: 3114: 3113: 3111: 3109: 3105: 3097: 3094: 3092: 3089: 3087: 3083: 3080: 3078: 3074: 3070: 3066: 3063: 3061: 3057: 3053: 3049: 3046: 3045: 3044: 3041: 3040: 3038: 3036: 3032: 3029: 3027: 3023: 3020: 3018: 3014: 3004: 3001: 2998: 2996: 2993: 2990: 2988: 2985: 2982: 2981: 2979: 2975: 2969: 2966: 2963: 2961: 2958: 2955: 2953: 2950: 2947: 2945: 2942: 2939: 2937: 2934: 2931: 2929: 2926: 2923: 2921: 2918: 2915: 2913: 2910: 2907: 2905: 2902: 2899: 2897: 2894: 2891: 2889: 2886: 2883: 2881: 2878: 2875: 2873: 2870: 2867: 2865: 2862: 2859: 2858: 2856: 2852: 2846: 2843: 2840: 2838: 2835: 2832: 2830: 2827: 2824: 2822: 2819: 2816: 2814: 2811: 2808: 2806: 2803: 2800: 2798: 2795: 2792: 2790: 2787: 2784: 2782: 2779: 2776: 2774: 2771: 2768: 2767: 2765: 2761: 2758: 2756: 2752: 2742: 2739: 2737: 2734: 2730: 2727: 2726: 2724: 2720: 2717: 2716: 2714: 2713: 2711: 2707: 2701: 2698: 2696: 2693: 2691: 2688: 2686: 2683: 2681: 2678: 2674: 2671: 2669: 2666: 2665: 2664: 2661: 2660: 2658: 2656: 2652: 2646: 2643: 2641: 2638: 2636: 2633: 2631: 2628: 2626: 2623: 2621: 2618: 2616: 2613: 2611: 2608: 2606: 2603: 2601: 2598: 2596: 2592: 2589: 2588: 2586: 2584: 2580: 2577: 2574: 2569: 2565: 2561: 2554: 2549: 2547: 2542: 2540: 2535: 2534: 2531: 2517: 2511: 2506: 2502: 2496: 2491: 2487: 2478: 2473: 2471: 2466: 2464: 2459: 2458: 2455: 2446: 2442: 2438: 2434: 2431:(2): 286–99. 2430: 2426: 2420: 2416: 2412: 2407: 2402: 2397: 2392: 2388: 2384: 2380: 2375: 2371: 2367: 2362: 2357: 2353: 2349: 2345: 2341: 2337: 2332: 2328: 2324: 2319: 2314: 2310: 2306: 2303:(6): 2011–7. 2302: 2298: 2294: 2289: 2285: 2281: 2276: 2271: 2267: 2263: 2259: 2254: 2250: 2246: 2242: 2238: 2234: 2230: 2224: 2220: 2216: 2211: 2206: 2202: 2198: 2194: 2189: 2185: 2181: 2176: 2171: 2167: 2163: 2159: 2154: 2150: 2146: 2141: 2136: 2133:(1): 169–79. 2132: 2128: 2124: 2119: 2115: 2111: 2106: 2101: 2097: 2093: 2089: 2084: 2080: 2076: 2071: 2066: 2062: 2058: 2054: 2050: 2046: 2041: 2037: 2033: 2030:(4): 1021–7. 2029: 2025: 2020: 2016: 2012: 2007: 2002: 1998: 1994: 1990: 1986: 1982: 1977: 1973: 1969: 1964: 1959: 1955: 1951: 1947: 1942: 1938: 1934: 1929: 1924: 1920: 1916: 1912: 1907: 1903: 1899: 1894: 1889: 1885: 1881: 1877: 1872: 1871: 1866: 1857: 1853: 1849: 1845: 1841: 1837: 1830: 1827: 1822: 1818: 1813: 1808: 1803: 1798: 1794: 1790: 1786: 1782: 1778: 1770: 1767: 1762: 1758: 1753: 1748: 1744: 1740: 1736: 1732: 1728: 1724: 1720: 1712: 1709: 1704: 1700: 1695: 1690: 1686: 1682: 1678: 1671: 1668: 1663: 1659: 1654: 1649: 1645: 1641: 1637: 1633: 1629: 1622: 1619: 1614: 1610: 1605: 1600: 1596: 1592: 1588: 1581: 1579: 1575: 1570: 1566: 1561: 1556: 1552: 1548: 1544: 1537: 1535: 1531: 1526: 1522: 1517: 1512: 1509:(6): 665–76. 1508: 1504: 1500: 1493: 1490: 1485: 1479: 1475: 1468: 1465: 1452: 1448: 1442: 1440: 1438: 1436: 1432: 1427: 1423: 1418: 1413: 1409: 1405: 1401: 1394: 1391: 1386: 1382: 1378: 1374: 1369: 1364: 1361:(3): 427–36. 1360: 1356: 1352: 1345: 1342: 1337: 1333: 1327: 1324: 1319: 1315: 1309: 1306: 1302: 1298: 1293: 1291: 1289: 1285: 1281: 1277: 1272: 1270: 1268: 1264: 1257: 1255: 1253: 1248: 1246: 1242: 1234: 1232: 1230: 1226: 1222: 1218: 1210: 1208: 1206: 1201: 1199: 1191: 1189: 1187: 1183: 1179: 1175: 1171: 1167: 1163: 1159: 1151: 1149: 1147: 1143: 1139: 1135: 1131: 1127: 1123: 1111: 1106: 1102: 1098: 1095: 1091: 1084: 1082: 1079: 1075: 1071: 1067: 1064: 1060: 1056: 1049: 1047: 1041: 1037: 1034: 1028: 1026: 1022: 1016: 1012: 1009: 1005: 998: 996: 990: 986: 983: 977: 975: 971: 965: 961: 958: 956:RefSeq (mRNA) 954: 947: 946: 941: 937: 934: 928: 927: 922: 918: 915: 913: 909: 902: 901: 896: 892: 889: 883: 882: 878: 873: 869: 866: 864: 860: 853: 852: 847: 843: 840: 834: 833: 828: 824: 821: 819: 815: 812: 809: 807: 804: 800: 797: 793: 789: 782: 778: 773: 767: 764: 762: 759: 757: 754: 752: 749: 747: 744: 742: 741:viral process 739: 737: 734: 732: 729: 727: 724: 722: 719: 717: 714: 712: 709: 707: 704: 702: 699: 697: 694: 692: 689: 687: 684: 683: 681: 678: 677: 671: 668: 666: 663: 661: 658: 656: 653: 651: 648: 647: 645: 642: 641: 635: 632: 630: 627: 625: 622: 620: 617: 615: 612: 611: 609: 606: 605: 602: 601:Gene ontology 598: 594: 582: 577: 573: 568: 565: 563: 559: 551: 546: 535: 531: 527: 523: 519: 515: 511: 507: 503: 499: 498: 495: 491: 486: 483: 473: 469: 465: 461: 457: 453: 449: 445: 441: 437: 436: 433: 429: 424: 421: 420: 417: 415: 411: 409: 408: 404: 403: 400: 398: 394: 390: 386: 382: 374: 369: 365: 361: 356: 346: 342: 335: 328: 322: 315: 307: 303: 299: 294: 290: 285: 281: 273: 268: 264: 260: 255: 245: 241: 234: 227: 221: 214: 210: 204: 200: 196: 191: 187: 182: 178: 174: 170: 166: 162: 158: 154: 150: 146: 142: 138: 130: 125: 118: 113: 108: 97: 95: 91: 87: 83: 77: 72: 69: 68: 64: 61: 54: 50: 45: 41: 37: 32: 27: 22: 4625: 4624: 4590:Lestaurtinib 4581: 4551: 4489:Ritlecitinib 4421:Lestaurtinib 4368:Upadacitinib 4197:Fontolizumab 4188: 4173: 4152: 4141:Rontalizumab 4122: 3980: 3935:Pegacaristim 3926: 3885: 3855: 3848:M-CSF (CSF1) 3828:Mavrilimumab 3824: 3818:Sargramostim 3808:Molgramostim 3793:Ecogramostim 3789: 3762:Nartograstim 3733: 3726:G-CSF (CSF3) 3711:Peginesatide 3691:Epoetin zeta 3656:Epoetin beta 3651:Epoetin alfa 3622: 3442:IL 17 family 3002: 2994: 2986: 2967: 2959: 2951: 2943: 2935: 2927: 2919: 2911: 2903: 2895: 2887: 2879: 2871: 2863: 2844: 2836: 2828: 2820: 2812: 2810:Fas receptor 2804: 2796: 2788: 2780: 2772: 2755:TNF receptor 2515: 2500: 2428: 2424: 2389:(6): 501–8. 2386: 2382: 2343: 2339: 2300: 2296: 2265: 2261: 2232: 2228: 2203:(1): 36–44. 2200: 2196: 2165: 2161: 2130: 2126: 2095: 2091: 2052: 2048: 2027: 2023: 1988: 1984: 1956:(1): 21–30. 1953: 1949: 1918: 1914: 1883: 1879: 1839: 1835: 1829: 1784: 1780: 1769: 1726: 1722: 1711: 1684: 1680: 1670: 1635: 1631: 1621: 1594: 1590: 1550: 1546: 1506: 1502: 1492: 1473: 1467: 1455:. Retrieved 1450: 1407: 1403: 1393: 1358: 1354: 1344: 1335: 1326: 1317: 1308: 1249: 1238: 1214: 1211:Interactions 1202: 1195: 1185: 1181: 1173: 1161: 1157: 1155: 1152:Nomenclature 1145: 1142:TNF-receptor 1133: 1129: 1125: 1121: 1120: 1043: 1021:NP_001284534 1018: 992: 970:NM_001297605 967: 943: 924: 898: 875: 849: 830: 810: 805: 412: 405: 371:155,013,020 358:155,006,390 132:External IDs 79: 4600:Quizartinib 4595:Midostaurin 4484:Peficitinib 4446:Ruxolitinib 4441:Peficitinib 4396:Baricitinib 4358:Ruxolitinib 4353:Peficitinib 4348:Oclacitinib 4343:Momelotinib 4328:Baricitinib 4323:Abrocitinib 4231:Interleukin 4189:Antibodies: 4146:Sifalimumab 4131:Faralimomab 4126:Anifrolumab 4123:Antibodies: 3945:Romiplostim 3930:Eltrombopag 3899:SCF (c-Kit) 3825:Antibodies: 3813:Regramostim 3747:Lenograstim 2928:(TNFRSF13C) 2920:(TNFRSF13B) 2912:(TNFRSF12A) 2904:(TNFRSF11B) 2896:(TNFRSF11A) 2888:(TNFRSF10D) 2880:(TNFRSF10C) 2872:(TNFRSF10B) 2864:(TNFRSF10A) 2483:PDB gallery 500:granulocyte 438:granulocyte 350:4|4 E2 110:Identifiers 4642:Categories 4585:Emfilermin 4436:Pacritinib 4338:Filgotinib 4304:inhibitors 4192:Emapalumab 3964:Interferon 3889:Agerafenib 3879:Mirimostim 3869:Lanimostim 3803:Milodistim 3752:Leridistim 3737:Filgrastim 3578:modulators 3003:(TNFRSF27) 2995:(TNFRSF25) 2987:(TNFRSF21) 2968:(TNFRSF19) 2960:(TNFRSF18) 2952:(TNFRSF17) 2944:(TNFRSF16) 2936:(TNFRSF14) 2821:(TNFRSF6B) 2781:(TNFRSF1B) 2773:(TNFRSF1A) 2406:1805/24635 1303:, May 2017 1282:, May 2017 1258:References 416:(ortholog) 270:2,565,382 257:2,555,639 153:HomoloGene 4610:Sunitinib 4605:Sorafenib 4514:ZM-449829 4504:WHI-P 154 4494:TCS-21311 4431:NSC-33994 4386:Atiprimod 4174:Agonists: 4156:Bifarcept 3981:Agonists: 3927:Agonists: 3859:Cilmostim 3856:Agonists: 3833:Namilumab 3790:Agonists: 3734:Agonists: 3623:Agonists: 3586:Chemokine 3287:prolactin 2845:(TNFRSF9) 2837:(TNFRSF8) 2829:(TNFRSF7) 2813:(TNFRSF6) 2805:(TNFRSF5) 2797:(TNFRSF4) 2789:(TNFRSF3) 1457:5 January 1046:NP_849262 1025:NP_003811 995:NM_178931 974:NM_003820 796:Orthologs 161:GeneCards 4509:ZM-39923 4426:NSC-7908 4391:AZD-1480 4282:instead. 4262:instead. 4242:instead. 4218:instead. 4136:MEDI-545 3910:instead. 3838:Otilimab 3641:CNTO-530 3597:instead. 3516:TGF-beta 3017:JAK-STAT 2965:TAJ/TROY 2445:15110526 2425:Virology 2415:14749527 2370:12915568 2327:12466117 2284:12093804 2249:11976496 2219:11756979 2184:11742858 2149:11511370 2114:11463856 2079:11390428 2036:10706119 1950:Immunity 1856:28277421 1821:22343534 1761:21796119 1703:10318773 1662:11390428 1525:19067971 1385:14626053 1299:– 1278:– 1217:interact 1192:Function 1146:TNFRSF14 1134:TNFRSF14 1094:Wikidata 775:Sources: 655:membrane 520:duodenum 508:yolk sac 450:duodenum 165:TNFRSF14 124:TNFRSF14 29:TNFRSF14 4451:SD-1008 3626:ARA-290 3512:Ser/Thr 3334:IL22RA2 3330:IL22RA1 3301:Type II 3230:IL12RB2 3226:IL12RB1 3209:IL12RB1 3108:β-chain 3077:IL13RA2 3073:IL13RA1 3035:γ-chain 2318:1850908 2015:9774688 1972:9462508 1937:9162022 1902:9153189 1812:3309757 1789:Bibcode 1752:3210554 1731:Bibcode 1613:9162022 1569:9153189 1426:9162061 1377:8898196 1301:Ensembl 1280:Ensembl 1225:TNFSF14 1176:in the 1140:of the 912:UniProt 863:Ensembl 802:Species 781:QuickGO 532:jejunum 391:pattern 249:1p36.32 149:2675303 117:Aliases 4545:Others 4411:CYT387 4401:CHZ868 4290:Others 4046:IFNA21 4042:IFNA17 4038:IFNA16 4034:IFNA14 4030:IFNA13 4026:IFNA10 3531:family 3526:TGFBR2 3521:TGFBR1 3475:IL17RE 3470:IL17RD 3465:IL17RC 3460:IL17RB 3455:IL17RA 3432:IL18R1 3385:IFNGR2 3381:IFNGR1 3372:IFNAR2 3368:IFNAR1 3347:IL20RB 3343:IL20RA 3322:IL10RB 3318:IL10RA 3252:other 3182:IL27RA 3173:IL11RA 3141:GM-CSF 3026:Type I 2909:TweakR 2741:CMKLR1 2719:CX3CR1 2443:  2413:  2368:  2361:187402 2358:  2325:  2315:  2282:  2247:  2217:  2182:  2147:  2112:  2077:  2070:209323 2067:  2034:  2013:  2006:109258 2003:  1970:  1935:  1900:  1854:  1819:  1809:  1759:  1749:  1723:Nature 1701:  1660:  1653:209323 1650:  1611:  1567:  1523:  1480:  1424:  1383:  1375:  1148:gene. 1080:search 1078:PubMed 945:Q80WM9 926:Q92956 851:230979 818:Entrez 562:BioGPS 528:spleen 512:embryo 504:thymus 442:spleen 141:602746 4085:IFNB3 4081:IFNB1 4022:IFNA8 4018:IFNA7 4014:IFNA6 4010:IFNA5 4006:IFNA4 4002:IFNA2 3998:IFNA1 3500:CSF1R 3428:IL18R 3421:IL1R2 3416:IL1R1 3352:IL28R 3339:IL20R 3326:IL22R 3314:IL10R 3264:G-CSF 3246:Other 3235:IL23R 3222:IL12R 3199:CNTFR 3164:IL6RA 3151:gp130 3134:IL5RA 3125:IL3RA 3096:IL21R 3086:IL7RA 3069:IL13R 3060:IL15R 3056:IL2RB 3052:IL2RA 3000:EDA2R 2977:21-27 2925:BAFFR 2854:11-20 2842:CD137 2794:CD134 2778:TNFR2 2770:TNFR1 2736:CCBP2 2715:CX3C 2709:Other 2700:CXCR7 2695:CXCR6 2690:CXCR5 2685:CXCR4 2680:CXCR3 2673:CXCR2 2668:CXCR1 2645:CCR10 2605:CCRL2 2595:CCRL1 2573:GPCRs 1381:S2CID 1229:TRAF5 1221:TRAF2 1219:with 1174:CD270 811:Mouse 806:Human 777:Amigo 536:blood 470:blood 414:Mouse 407:Human 354:Start 289:Mouse 253:Start 186:Human 4524:TYK2 4466:JAK3 4378:JAK2 4315:JAK1 4280:here 4278:See 4260:here 4258:See 4251:TGFβ 4240:here 4238:See 4216:here 3908:here 3906:See 3595:here 3593:See 3450:IL17 3364:-α/β 3194:LIFR 3189:OSMR 3130:IL5R 3121:IL3R 3091:IL9R 3082:IL7R 3065:IL4R 3048:IL2R 2957:GITR 2949:BCMA 2941:NGFR 2933:HVEM 2917:TACI 2893:RANK 2885:DcR2 2877:DcR1 2834:CD30 2826:CD27 2818:DcR3 2802:CD40 2786:LTBR 2763:1-10 2729:XCR1 2663:IL-8 2640:CCR9 2635:CCR8 2630:CCR7 2625:CCR6 2620:CCR5 2615:CCR4 2610:CCR3 2600:CCR2 2591:CCR1 2516:2aw2 2501:1jma 2441:PMID 2411:PMID 2366:PMID 2323:PMID 2280:PMID 2245:PMID 2215:PMID 2180:PMID 2145:PMID 2110:PMID 2075:PMID 2032:PMID 2011:PMID 1968:PMID 1933:PMID 1898:PMID 1852:PMID 1817:PMID 1757:PMID 1699:PMID 1658:PMID 1609:PMID 1565:PMID 1521:PMID 1478:ISBN 1459:2024 1451:Gene 1422:PMID 1373:PMID 1355:Cell 1243:and 1227:and 1205:MITF 1182:ATAR 1170:HveC 1168:and 1166:HveB 1162:HveA 1126:HVEM 832:8764 397:Bgee 345:Band 306:Chr. 244:Band 203:Chr. 157:2833 137:OMIM 94:4RSU 90:4FHQ 86:2AW2 82:1JMA 63:RCSB 60:PDBe 4298:JAK 4271:TNF 3606:CSF 3505:KIT 3495:Tyr 3411:IL1 3259:EPO 2992:DR3 2984:DR6 2869:DR5 2861:DR4 2725:XC 2655:CXC 2433:doi 2429:322 2401:hdl 2391:doi 2356:PMC 2348:doi 2313:PMC 2305:doi 2301:161 2270:doi 2266:277 2237:doi 2205:doi 2201:185 2170:doi 2135:doi 2100:doi 2065:PMC 2057:doi 2053:107 2001:PMC 1993:doi 1958:doi 1923:doi 1919:272 1888:doi 1884:272 1844:doi 1807:PMC 1797:doi 1785:109 1747:PMC 1739:doi 1727:476 1689:doi 1685:274 1648:PMC 1640:doi 1636:107 1599:doi 1595:272 1555:doi 1551:272 1511:doi 1412:doi 1408:272 1363:doi 1188:). 1164:); 524:lip 367:End 266:End 169:OMA 145:MGI 53:PDB 4644:: 4083:, 4044:, 4040:, 4036:, 4032:, 4028:, 4024:, 4020:, 4016:, 4012:, 4008:, 4004:, 4000:, 3514:: 3430:/ 3383:/ 3377:-γ 3366:/ 3345:/ 3341:/ 3332:/ 3328:/ 3324:/ 3320:/ 3316:/ 3282:GH 3280:: 3178:27 3169:11 3132:/ 3123:/ 3084:/ 3075:/ 3071:/ 3067:/ 3058:/ 3050:/ 2593:/ 2583:CC 2439:. 2427:. 2409:. 2399:. 2387:35 2385:. 2381:. 2364:. 2354:. 2344:77 2342:. 2338:. 2321:. 2311:. 2299:. 2295:. 2278:. 2264:. 2260:. 2243:. 2233:58 2231:. 2213:. 2199:. 2195:. 2178:. 2166:21 2164:. 2160:. 2143:. 2129:. 2125:. 2108:. 2096:15 2094:. 2090:. 2073:. 2063:. 2051:. 2047:. 2028:60 2026:. 2009:. 1999:. 1989:18 1987:. 1983:. 1966:. 1952:. 1948:. 1931:. 1917:. 1913:. 1896:. 1882:. 1878:. 1850:. 1840:24 1838:. 1815:. 1805:. 1795:. 1783:. 1779:. 1755:. 1745:. 1737:. 1725:. 1721:. 1697:. 1683:. 1679:. 1656:. 1646:. 1634:. 1630:. 1607:. 1593:. 1589:. 1577:^ 1563:. 1549:. 1545:. 1533:^ 1519:. 1507:21 1505:. 1501:. 1449:. 1434:^ 1420:. 1406:. 1402:. 1379:. 1371:. 1359:87 1357:. 1353:. 1334:. 1316:. 1287:^ 1266:^ 1247:. 1231:. 1223:, 1207:. 779:/ 373:bp 360:bp 272:bp 259:bp 167:; 163:: 159:; 155:: 151:; 147:: 143:; 139:: 92:, 88:, 84:, 4634:. 4306:) 4302:( 4087:) 4079:( 4048:) 3996:( 3567:e 3560:t 3553:v 3379:/ 3370:/ 3228:/ 3224:/ 3180:/ 3171:/ 3054:/ 2575:) 2571:( 2552:e 2545:t 2538:v 2476:e 2469:t 2462:v 2447:. 2435:: 2417:. 2403:: 2393:: 2372:. 2350:: 2329:. 2307:: 2286:. 2272:: 2251:. 2239:: 2221:. 2207:: 2186:. 2172:: 2151:. 2137:: 2131:8 2116:. 2102:: 2081:. 2059:: 2038:. 2017:. 1995:: 1974:. 1960:: 1954:8 1939:. 1925:: 1904:. 1890:: 1858:. 1846:: 1823:. 1799:: 1791:: 1763:. 1741:: 1733:: 1705:. 1691:: 1664:. 1642:: 1615:. 1601:: 1571:. 1557:: 1527:. 1513:: 1486:. 1461:. 1428:. 1414:: 1387:. 1365:: 1338:. 1320:. 1184:( 1160:( 1132:( 1124:( 291:) 188:) 171:: 23:.

Index

CityPlace, Toronto

PDB
PDBe
RCSB
1JMA
2AW2
4FHQ
4RSU
Aliases
TNFRSF14
OMIM
602746
MGI
2675303
HomoloGene
2833
GeneCards
TNFRSF14
OMA
TNFRSF14 - orthologs
Human
Chromosome 1 (human)
Chr.
Chromosome 1 (human)
Chromosome 1 (human)
Genomic location for TNFRSF14
Genomic location for TNFRSF14
Band
bp

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.