Knowledge (XXG)

IL13RA2

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Gauchat JF, Schlagenhauf E, Feng NP, Moser R, Yamage M, Jeannin P, Alouani S, Elson G, Notarangelo LD, Wells T, Eugster HP, Bonnefoy JY (April 1997). "A novel 4-kb interleukin-13 receptor alpha mRNA expressed in human B, T, and endothelial cells encoding an alternate type-II
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Donaldson DD, Whitters MJ, Fitz LJ, Neben TY, Finnerty H, Henderson SL, O'Hara RM, Beier DR, Turner KJ, Wood CR, Collins M (September 1998). "The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1".
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Granel B, Allanore Y, Chevillard C, Arnaud V, Marquet S, Weiller PJ, Durand JM, Harlé JR, Grange C, Frances Y, Berbis P, Gaudart J, de Micco P, Kahan A, Dessein A (October 2006). "IL13RA2 gene polymorphisms are associated with systemic sclerosis".
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Okano F, Storkus WJ, Chambers WH, Pollack IF, Okada H (September 2002). "Identification of a novel HLA-A*0201-restricted, cytotoxic T lymphocyte epitope in a human glioma-associated antigen, interleukin 13 receptor alpha2 chain".
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Okamoto H, Yoshimatsu Y, Tomizawa T, Kunita A, Takayama R, Morikawa T, Komura D, Takahashi K, Oshima T, Sato M, Komai M, Podyma-Inoue KA, Uchida H, Hamada H, Fujiu K, Ishikawa S, Fukayama M, Fukuhara T, Watabe T (February 2019).
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Osawa M, Miyoshi S, Copeland NG, Gilbert DJ, Jenkins NA, Hiroyama T, Motohashi T, Nakamura Y, Iwama A, Nakauchi H (September 2000). "Characterization of the mouse interleukin-13 receptor alpha1 gene".
1676:"A novel mechanism by which interferon-gamma can regulate interleukin (IL)-13 responses. Evidence for intracellular stores of IL-13 receptor alpha -2 and their rapid mobilization by interferon-gamma" 1464:"Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned Il-13 receptor and Il-4 receptor alpha-chains" 1889:
Fichtner-Feigl S, Strober W, Kawakami K, Puri RK, Kitani A (January 2006). "IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis".
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with high affinity, but lacks any significant cytoplasmic domain, and does not appear to function as a signal mediator. It is, however, able to regulate the effects of both IL-13 and
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Cancino-Díaz JC, Reyes-Maldonado E, Bañuelos-Pánuco CA, Jiménez-Zamudio L, García-Latorre E, León-Dorantes G, Blancas-González F, Paredes-Cabrera G, Cancino-Díaz ME (November 2002).
2100: 312: 211: 5438: 2951: 1641:"Identification of distinct roles for a dileucine and a tyrosine internalization motif in the interleukin (IL)-13 binding component IL-13 receptor alpha 2 chain" 4130: 2931: 2068: 763: 744: 3793: 2117: 2093: 134: 4123: 1535:
Guo J, Apiou F, Mellerin MP, Lebeau B, Jacques Y, Minvielle S (May 1997). "Chromosome mapping and expression of the human interleukin-13 receptor".
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IL-13Rα2 has been found to be over-expressed in a variety of cancers, including pancreatic, ovarian, melanomas, and malignant gliomas.
971: 298: 5259: 1429:"Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain" 978: 4207: 4024: 1358:"Interleukin-13 receptor alpha chain: a novel tumor-associated transmembrane protein in primary explants of human malignant gliomas" 1076:, despite the fact it is unable to bind directly to the latter. It is also reported to play a role in the internalization of IL13. 275: 1462:
Zhang JG, Hilton DJ, Willson TA, McFarlane C, Roberts BA, Moritz RL, Simpson RJ, Alexander WS, Metcalf D, Nicola NA (April 1997).
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David M, Bertoglio J, Pierre J (November 2002). "TNF-alpha potentiates IL-4/IL-13-induced IL-13Ralpha2 expression".
304: 203: 3688: 2113: 1733:"Interleukin-13 receptor in psoriatic keratinocytes: overexpression of the mRNA and underexpression of the protein" 1038: 2554: 3738: 2633: 2037: 808: 122: 1963:"Interleukin-13 receptor alpha2 chain: a potential biomarker and molecular target for ovarian cancer therapy" 1251:"Interleukin-13 receptor alpha2 chain: a potential biomarker and molecular target for ovarian cancer therapy" 5178: 5138: 5117: 5061: 5029: 4988: 4946: 4900: 4819: 4793: 4737: 4696: 4670: 4644: 4298: 3702: 1093: 1065: 789: 4753: 4613: 4593: 4572: 4491: 4430: 4374: 4328: 4252: 4157: 3045: 3040: 3035: 3025: 2332: 2260: 2389: 2307: 1394:"IL-13 receptor alpha 2: a regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts" 4263: 1813:"Molecular cloning and identification of the human interleukin 13 alpha 2 receptor (IL-13Ra2) promoter" 5375: 5158: 4146: 3626: 3339: 1775: 1312: 186: 4288: 2033: 101: 5149: 4707: 4502: 4278: 4172: 3653: 3472: 1854:
Arima K, Sato K, Tanaka G, Kanaji S, Terada T, Honjo E, Kuroki R, Matsuo Y, Izuhara K (July 2005).
950: 903: 5019: 5014: 1301:"Interleukin-13 receptor α2 is a novel marker and potential therapeutic target for human melanoma" 4999: 4911: 4890: 4339: 4273: 4232: 4176: 4149: 3060: 2794: 1992: 1914: 1799: 1627: 1590: 1523: 1280: 146: 4880: 4748: 4655: 4634: 4385: 4354: 4349: 4293: 4212: 954: 929: 899: 878: 4926: 4359: 4187: 4182: 4532: 4517: 4481: 4451: 4197: 2044: 2014: 1984: 1949: 1906: 1877: 1842: 1791: 1754: 1719: 1697: 1662: 1619: 1582: 1552: 1515: 1485: 1450: 1415: 1369: 1338: 1272: 1231: 549: 94: 42: 5408: 1210:"A novel role of interleukin-13 receptor alpha2 in pancreatic cancer invasion and metastasis" 142: 5404: 5396: 5370: 3833: 3566: 3487: 3050: 2243: 2169: 1974: 1939: 1898: 1867: 1832: 1824: 1783: 1744: 1687: 1652: 1611: 1574: 1544: 1507: 1475: 1440: 1405: 1328: 1320: 1262: 1221: 391: 322: 266: 221: 4846: 4842: 4838: 5162: 3893: 2429: 2424: 2347: 366: 1928:"Level of expression of IL-13R alpha 2 impacts receptor distribution and IL-13 signaling" 1856:"Characterization of the interaction between interleukin-13 and interleukin-13 receptors" 1779: 1316: 5360: 5350: 5345: 5331: 5317: 5307: 5302: 5249: 5231: 5210: 5189: 5168: 5154: 5128: 5072: 5040: 5004: 4967: 4962: 4957: 4921: 4916: 4830: 4809: 4763: 4712: 4681: 4660: 4395: 4364: 3678: 3100: 2611: 2414: 1837: 1812: 1787: 1333: 1300: 1209: 1069: 1357: 678: 673: 668: 663: 647: 642: 637: 632: 627: 622: 606: 601: 591: 5451: 5102: 4758: 4624: 4583: 4507: 4441: 4390: 4344: 4283: 4168: 3648: 3105: 2196: 2072: 2053: 1749: 1732: 1594: 1392:
Andrews AL, Nasir T, Bucchieri F, Holloway JW, Holgate ST, Davies DE (October 2006).
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Daines MO, Tabata Y, Walker BA, Chen W, Warrier MR, Basu S, Hershey GK (June 2006).
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Caput D, Laurent P, Kaghad M, Lelias JM, Lefort S, Vita N, Ferrara P (July 1996).
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Kioi M, Kawakami M, Shimamura T, Husain SR, Puri RK (September 2006).
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Kioi M, Kawakami M, Shimamura T, Husain SR, Puri RK (September 2006).
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Overview of all the structural information available in the
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Fujisawa T, Joshi B, Nakajima A, Puri RK (November 2009).
374: 5412: 1195:"Entrez Gene: IL13RA2 interleukin 13 receptor, alpha 2" 539: 5295: 5275: 5268: 5219: 5198: 5177: 5137: 5116: 5060: 5028: 4987: 4945: 4899: 4818: 4792: 4736: 4695: 4669: 4643: 4612: 4592: 4571: 4490: 4429: 4373: 4327: 4251: 4156: 3917: 3711: 3460: 3144: 2867: 2527: 2125: 943: 922: 892: 871: 510:
dentate gyrus of hippocampal formation granule cell
1134: 1132: 1130: 1113: 1111: 1109: 2057:(Interleukin-13 receptor subunit alpha-2) at the 321: 220: 669:negative regulation of immunoglobulin production 18:Protein-coding gene in the species Homo sapiens 1639:Kawakami K, Takeshita F, Puri RK (July 2001). 1398:The Journal of Allergy and Clinical Immunology 1139:GRCm38: Ensembl release 89: ENSMUSG00000031289 664:negative regulation of mast cell degranulation 5432: 4131: 2094: 8: 1356:Joshi BH, Plautz GE, Puri RK (March 2000). 1118:GRCh38: Ensembl release 89: ENSG00000123496 5439: 5425: 5272: 4138: 4124: 4116: 2101: 2087: 2079: 2069:United States National Library of Medicine 1768:Annals of the New York Academy of Sciences 704: 574: 362: 261: 158: 60: 2118:list of human clusters of differentiation 2036:at the U.S. National Library of Medicine 1978: 1943: 1871: 1836: 1748: 1691: 1656: 1479: 1444: 1409: 1332: 1266: 1225: 5303:Interleukin 14 (taxilin alpha, HMW-BCGF) 2067:This article incorporates text from the 1737:The Journal of Investigative Dermatology 1498:interleukin-4/interleukin-13 receptor". 1189: 1187: 1105: 1031:Interleukin-13 receptor subunit alpha-2 674:immunoglobulin mediated immune response 4601:See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) 20: 326: 287: 282: 225: 184: 179: 7: 5393: 5391: 1674:Daines MO, Hershey GK (March 2002). 1860:The Journal of Biological Chemistry 1680:The Journal of Biological Chemistry 1645:The Journal of Biological Chemistry 1468:The Journal of Biological Chemistry 1433:The Journal of Biological Chemistry 679:cytokine-mediated signaling pathway 5411:. You can help Knowledge (XXG) by 1788:10.1111/j.1749-6632.2002.tb04633.x 940: 919: 889: 868: 844: 825: 799: 780: 754: 735: 544: 462: 400: 379: 14: 1045:that in humans is encoded by the 5395: 1750:10.1046/j.1523-1747.2002.19509.x 1060:IL-13Rα2 is closely related to 643:external side of plasma membrane 548: 310: 303: 297: 274: 209: 202: 196: 171: 5129:Interleukin 27 (interleukin 30) 1500:European Journal of Immunology 623:integral component of membrane 559:More reference expression data 528:More reference expression data 1: 1227:10.1158/0008-5472.CAN-09-2100 295: 194: 1945:10.4049/jimmunol.176.12.7495 1068:complex. This protein binds 1041:213A2), is a membrane bound 5463:Clusters of differentiation 5458:Genes on human chromosome X 4479:Antisense oligonucleotides: 2114:clusters of differentiation 2007:The Journal of Rheumatology 1811:Wu AH, Low WC (July 2003). 1579:10.4049/jimmunol.161.5.2317 5484: 5390: 1411:10.1016/j.jaci.2006.06.041 1325:10.1038/s41598-019-39018-3 1039:cluster of differentiation 1033:(IL-13Rα2), also known as 597:signal transducer activity 592:cytokine receptor activity 1829:10.1215/s1152851702000510 1174:"Mouse PubMed Reference:" 1156:"Human PubMed Reference:" 1017: 1012: 1008: 1001: 985: 979:Chr X: 146.17 – 146.21 Mb 966: 947: 926: 915: 896: 875: 864: 851: 847: 832: 828: 819: 806: 802: 787: 783: 774: 761: 757: 742: 738: 729: 714: 707: 703: 687: 577: 573: 556: 547: 538: 525: 474: 465: 420:Descending thoracic aorta 412: 403: 373: 365: 361: 344: 331: 294: 273: 264: 260: 243: 230: 193: 170: 161: 157: 112: 109: 99: 92: 87: 68: 63: 46: 41: 36: 32: 28: 23: 2038:Medical Subject Headings 1712:Clinical Cancer Research 1446:10.1074/jbc.271.28.16921 5169:Interleukin-29 (IFN-λ1) 4314:Daclizumab (dacliximab) 4299:Tucotuzumab celmoleukin 1481:10.1074/jbc.272.14.9474 1094:Interleukin-13 receptor 1066:interleukin-13 receptor 5468:Membrane protein stubs 5407:–related article is a 5150:Interferon λ4 (IFN-λ4) 4243:Rilonacept (IL-1 Trap) 2034:IL13RA2+protein,+human 1873:10.1074/jbc.M502571200 1693:10.1074/jbc.M108109200 1658:10.1074/jbc.M100936200 1549:10.1006/geno.1997.4628 1512:10.1002/eji.1830270425 972:Chr X: 115 – 115.02 Mb 486:mesenteric lymph nodes 444:metanephric glomerulus 5073:Interleukin 23 (SGRF) 4754:Cintredekin besudotox 4682:Interleukin 11 (AGIF) 4661:Interleukin 10 (CSIF) 1932:Journal of Immunology 1616:10.1007/s002510000225 1567:Journal of Immunology 1080:Clinical Significance 4147:Interleukin receptor 633:extracellular region 514:skin of external ear 328:X F2|X 68.46 cM 289:X chromosome (mouse) 187:X chromosome (human) 64:List of PDB id codes 37:Available structures 4279:Denileukin diftitox 1780:2002NYASA.973..207D 1317:2019NatSR...9.1281O 1064:, a subunit of the 638:extracellular space 151:IL13RA2 - orthologs 4851:E (interleukin 25) 2071:, which is in the 1980:10.1002/cncr.22134 1305:Scientific Reports 1268:10.1002/cncr.22134 809:ENSMUSG00000031289 657:Biological process 616:Cellular component 585:Molecular function 452:anterior pituitary 5420: 5419: 5388: 5387: 5384: 5383: 5353:(signals through 5334:(signals through 5320:(signals through 5310:(signals through 4934:Binding proteins: 4264:Adargileukin alfa 4113: 4112: 1028: 1027: 1024: 1023: 997: 996: 962: 961: 937: 936: 911: 910: 886: 885: 860: 859: 841: 840: 815: 814: 796: 795: 770: 769: 751: 750: 699: 698: 569: 568: 565: 564: 534: 533: 521: 520: 459: 458: 357: 356: 256: 255: 83: 82: 79: 78: 47:Ortholog search: 5475: 5441: 5434: 5427: 5405:membrane protein 5399: 5392: 5376:Efineptakin alfa 5371:Efavaleukin alfa 5273: 4240:Decoy receptors: 4140: 4133: 4126: 4117: 2103: 2096: 2089: 2080: 2022: 2000: 1982: 1957: 1947: 1938:(12): 7495–501. 1922: 1885: 1875: 1866:(26): 24915–22. 1850: 1840: 1807: 1762: 1752: 1727: 1705: 1695: 1686:(12): 10387–93. 1670: 1660: 1651:(27): 25114–20. 1635: 1598: 1560: 1531: 1493: 1483: 1458: 1448: 1423: 1413: 1378: 1377: 1353: 1347: 1346: 1336: 1295: 1289: 1288: 1270: 1246: 1240: 1239: 1229: 1205: 1199: 1198: 1191: 1182: 1181: 1170: 1164: 1163: 1152: 1146: 1136: 1125: 1115: 1010: 1009: 981: 974: 957: 941: 932: 920: 916:RefSeq (protein) 906: 890: 881: 869: 845: 826: 800: 781: 755: 736: 705: 648:receptor complex 607:cytokine binding 575: 561: 552: 545: 530: 470: 468:Top expressed in 463: 408: 406:Top expressed in 401: 380: 363: 353: 340: 329: 314: 307: 301: 290: 278: 262: 252: 239: 228: 213: 206: 200: 189: 175: 159: 153: 104: 97: 74: 61: 55: 34: 33: 21: 5483: 5482: 5478: 5477: 5476: 5474: 5473: 5472: 5448: 5447: 5446: 5445: 5389: 5380: 5291: 5264: 5215: 5194: 5173: 5133: 5112: 5056: 5053:(against IL-22) 5024: 4983: 4980:(against IL-20) 4941: 4895: 4814: 4788: 4732: 4691: 4665: 4639: 4608: 4588: 4567: 4486: 4425: 4369: 4323: 4247: 4152: 4144: 4114: 4109: 3913: 3707: 3456: 3140: 2863: 2523: 2121: 2107: 2065: 2030: 2025: 2003: 1960: 1925: 1891:Nature Medicine 1888: 1853: 1810: 1765: 1730: 1708: 1673: 1638: 1601: 1563: 1534: 1496: 1474:(14): 9474–80. 1461: 1439:(28): 16921–6. 1426: 1391: 1387: 1385:Further reading 1382: 1381: 1362:Cancer Research 1355: 1354: 1350: 1297: 1296: 1292: 1248: 1247: 1243: 1220:(22): 8678–85. 1214:Cancer Research 1207: 1206: 1202: 1193: 1192: 1185: 1172: 1171: 1167: 1154: 1153: 1149: 1137: 1128: 1116: 1107: 1102: 1090: 1082: 1058: 1019:View/Edit Mouse 1014:View/Edit Human 977: 970: 967:Location (UCSC) 953: 949: 928: 902: 898: 877: 790:ENSG00000123496 683: 652: 611: 602:protein binding 557: 526: 517: 512: 508: 504: 502:ascending aorta 500: 496: 492: 488: 484: 480: 466: 455: 450: 446: 442: 438: 434: 430: 426: 424:ascending aorta 422: 418: 404: 348: 335: 327: 317: 316: 315: 308: 288: 265:Gene location ( 247: 234: 226: 216: 215: 214: 207: 185: 162:Gene location ( 113: 100: 93: 70: 48: 19: 12: 11: 5: 5481: 5479: 5471: 5470: 5465: 5460: 5450: 5449: 5444: 5443: 5436: 5429: 5421: 5418: 5417: 5400: 5386: 5385: 5382: 5381: 5379: 5378: 5373: 5364: 5363: 5361:Interleukin 35 5358: 5351:Interleukin 34 5348: 5346:Interleukin 32 5343: 5332:Interleukin 26 5329: 5318:Interleukin 24 5315: 5308:Interleukin 16 5305: 5299: 5297: 5293: 5292: 5290: 5289: 5281: 5279: 5270: 5266: 5265: 5263: 5262: 5253: 5252: 5250:Interleukin 38 5247: 5232:Interleukin 36 5225: 5223: 5217: 5216: 5214: 5213: 5211:Interleukin 33 5204: 5202: 5196: 5195: 5193: 5192: 5190:Interleukin 31 5183: 5181: 5175: 5174: 5172: 5171: 5166: 5155:Interleukin 28 5152: 5143: 5141: 5135: 5134: 5132: 5131: 5122: 5120: 5114: 5113: 5111: 5110: 5105: 5100: 5095: 5090: 5085: 5076: 5075: 5066: 5064: 5058: 5057: 5055: 5054: 5044: 5043: 5041:Interleukin 22 5034: 5032: 5026: 5025: 5023: 5022: 5017: 5008: 5007: 5005:Interleukin 21 5002: 4993: 4991: 4985: 4984: 4982: 4981: 4971: 4970: 4968:Interleukin 24 4965: 4963:Interleukin 20 4960: 4958:Interleukin 19 4951: 4949: 4943: 4942: 4940: 4939: 4930: 4929: 4924: 4922:Interleukin 37 4919: 4917:Interleukin 18 4914: 4905: 4903: 4897: 4896: 4894: 4893: 4888: 4883: 4878: 4873: 4868: 4859: 4858: 4831:Interleukin 17 4824: 4822: 4816: 4815: 4813: 4812: 4810:Interleukin 15 4807: 4798: 4796: 4790: 4789: 4787: 4786: 4781: 4776: 4767: 4766: 4764:Interleukin 13 4761: 4756: 4751: 4742: 4740: 4734: 4733: 4731: 4730: 4725: 4716: 4715: 4713:Interleukin 12 4710: 4701: 4699: 4693: 4692: 4690: 4689: 4684: 4675: 4673: 4667: 4666: 4664: 4663: 4658: 4649: 4647: 4641: 4640: 4638: 4637: 4628: 4627: 4618: 4616: 4610: 4609: 4607: 4606: 4598: 4596: 4590: 4589: 4587: 4586: 4577: 4575: 4569: 4568: 4566: 4565: 4560: 4555: 4550: 4545: 4540: 4535: 4530: 4525: 4520: 4511: 4510: 4505: 4496: 4494: 4488: 4487: 4485: 4484: 4475: 4474: 4469: 4464: 4455: 4454: 4445: 4444: 4435: 4433: 4427: 4426: 4424: 4423: 4418: 4409: 4408: 4399: 4398: 4396:Interleukin 13 4393: 4388: 4379: 4377: 4371: 4370: 4368: 4367: 4365:Promegapoietin 4362: 4357: 4352: 4347: 4342: 4333: 4331: 4325: 4324: 4322: 4321: 4316: 4311: 4302: 4301: 4296: 4291: 4289:Pegaldesleukin 4286: 4281: 4276: 4271: 4266: 4257: 4255: 4249: 4248: 4246: 4245: 4236: 4235: 4230: 4225: 4216: 4215: 4210: 4205: 4200: 4191: 4190: 4185: 4180: 4162: 4160: 4154: 4153: 4145: 4143: 4142: 4135: 4128: 4120: 4111: 4110: 4108: 4107: 4102: 4097: 4092: 4087: 4082: 4077: 4072: 4067: 4062: 4057: 4052: 4047: 4042: 4037: 4032: 4027: 4022: 4017: 4012: 4007: 4002: 3997: 3992: 3987: 3982: 3977: 3972: 3967: 3962: 3957: 3952: 3947: 3942: 3937: 3932: 3927: 3921: 3919: 3915: 3914: 3912: 3911: 3906: 3901: 3896: 3891: 3886: 3881: 3876: 3871: 3866: 3861: 3856: 3851: 3846: 3841: 3836: 3831: 3826: 3821: 3816: 3811: 3806: 3801: 3796: 3791: 3786: 3781: 3776: 3771: 3766: 3761: 3756: 3751: 3746: 3741: 3736: 3731: 3726: 3721: 3715: 3713: 3709: 3708: 3706: 3705: 3700: 3691: 3686: 3681: 3676: 3671: 3666: 3661: 3656: 3651: 3646: 3645: 3644: 3639: 3629: 3624: 3619: 3614: 3609: 3604: 3599: 3594: 3589: 3584: 3579: 3574: 3569: 3564: 3558: 3549: 3544: 3543: 3542: 3537: 3527: 3522: 3521: 3520: 3515: 3505: 3500: 3495: 3490: 3485: 3480: 3475: 3470: 3464: 3462: 3458: 3457: 3455: 3454: 3449: 3444: 3439: 3434: 3429: 3424: 3419: 3414: 3409: 3404: 3399: 3394: 3389: 3384: 3379: 3374: 3369: 3368: 3367: 3362: 3352: 3347: 3342: 3337: 3336: 3335: 3330: 3325: 3315: 3310: 3305: 3300: 3295: 3294: 3293: 3288: 3278: 3273: 3268: 3263: 3258: 3253: 3248: 3247: 3246: 3241: 3231: 3225: 3220: 3215: 3210: 3201: 3196: 3195: 3194: 3189: 3184: 3174: 3169: 3164: 3159: 3154: 3148: 3146: 3142: 3141: 3139: 3138: 3133: 3128: 3123: 3118: 3113: 3108: 3103: 3098: 3093: 3088: 3083: 3078: 3073: 3068: 3063: 3058: 3053: 3048: 3043: 3038: 3033: 3028: 3023: 3018: 3013: 3012: 3011: 3006: 2996: 2995: 2994: 2989: 2979: 2974: 2969: 2964: 2959: 2954: 2949: 2944: 2939: 2934: 2929: 2924: 2919: 2918: 2917: 2912: 2902: 2897: 2892: 2887: 2882: 2877: 2871: 2869: 2865: 2864: 2862: 2861: 2856: 2851: 2846: 2841: 2836: 2831: 2826: 2821: 2812: 2807: 2802: 2797: 2792: 2787: 2786: 2785: 2780: 2775: 2770: 2765: 2760: 2750: 2745: 2740: 2735: 2730: 2725: 2724: 2723: 2718: 2708: 2703: 2698: 2693: 2688: 2683: 2678: 2673: 2668: 2667: 2666: 2661: 2656: 2651: 2646: 2641: 2631: 2630: 2629: 2624: 2619: 2609: 2604: 2603: 2602: 2597: 2592: 2582: 2577: 2572: 2567: 2562: 2557: 2552: 2547: 2542: 2537: 2531: 2529: 2525: 2524: 2522: 2521: 2516: 2515: 2514: 2509: 2504: 2499: 2494: 2489: 2479: 2474: 2469: 2464: 2459: 2454: 2449: 2448: 2447: 2442: 2437: 2432: 2422: 2417: 2412: 2407: 2402: 2397: 2392: 2387: 2382: 2377: 2376: 2375: 2370: 2360: 2355: 2350: 2345: 2340: 2335: 2330: 2325: 2320: 2315: 2310: 2305: 2300: 2295: 2290: 2289: 2288: 2283: 2273: 2268: 2263: 2258: 2257: 2256: 2251: 2246: 2241: 2231: 2226: 2221: 2220: 2219: 2209: 2204: 2199: 2194: 2189: 2188: 2187: 2182: 2177: 2167: 2162: 2161: 2160: 2155: 2150: 2145: 2140: 2129: 2127: 2123: 2122: 2108: 2106: 2105: 2098: 2091: 2083: 2063: 2062: 2041: 2029: 2028:External links 2026: 2024: 2023: 2013:(10): 2015–9. 2001: 1973:(6): 1407–18. 1958: 1923: 1903:10.1038/nm1332 1886: 1851: 1817:Neuro-Oncology 1808: 1763: 1743:(5): 1114–20. 1728: 1706: 1671: 1636: 1610:(11): 974–81. 1604:Immunogenetics 1599: 1573:(5): 2317–24. 1561: 1532: 1494: 1459: 1424: 1388: 1386: 1383: 1380: 1379: 1368:(5): 1168–72. 1348: 1290: 1261:(6): 1407–18. 1241: 1200: 1183: 1165: 1147: 1126: 1104: 1103: 1101: 1098: 1097: 1096: 1089: 1086: 1081: 1078: 1057: 1054: 1026: 1025: 1022: 1021: 1016: 1006: 1005: 999: 998: 995: 994: 992: 990: 983: 982: 975: 968: 964: 963: 960: 959: 945: 944: 938: 935: 934: 924: 923: 917: 913: 912: 909: 908: 894: 893: 887: 884: 883: 873: 872: 866: 862: 861: 858: 857: 849: 848: 842: 839: 838: 830: 829: 823: 817: 816: 813: 812: 804: 803: 797: 794: 793: 785: 784: 778: 772: 771: 768: 767: 759: 758: 752: 749: 748: 740: 739: 733: 727: 726: 721: 716: 712: 711: 701: 700: 697: 696: 685: 684: 682: 681: 676: 671: 666: 660: 658: 654: 653: 651: 650: 645: 640: 635: 630: 625: 619: 617: 613: 612: 610: 609: 604: 599: 594: 588: 586: 582: 581: 571: 570: 567: 566: 563: 562: 554: 553: 542: 536: 535: 532: 531: 523: 522: 519: 518: 516: 515: 511: 507: 503: 499: 495: 491: 487: 483: 479: 475: 472: 471: 460: 457: 456: 454: 453: 449: 445: 441: 437: 433: 429: 425: 421: 417: 413: 410: 409: 397: 396: 388: 377: 371: 370: 367:RNA expression 359: 358: 355: 354: 346: 342: 341: 333: 330: 325: 319: 318: 309: 302: 296: 292: 291: 286: 280: 279: 271: 270: 258: 257: 254: 253: 245: 241: 240: 232: 229: 224: 218: 217: 208: 201: 195: 191: 190: 183: 177: 176: 168: 167: 155: 154: 111: 107: 106: 98: 90: 89: 85: 84: 81: 80: 77: 76: 66: 65: 57: 56: 45: 39: 38: 30: 29: 26: 25: 17: 13: 10: 9: 6: 4: 3: 2: 5480: 5469: 5466: 5464: 5461: 5459: 5456: 5455: 5453: 5442: 5437: 5435: 5430: 5428: 5423: 5422: 5416: 5414: 5410: 5406: 5401: 5398: 5394: 5377: 5374: 5372: 5369: 5366: 5365: 5362: 5359: 5356: 5352: 5349: 5347: 5344: 5341: 5337: 5333: 5330: 5327: 5323: 5319: 5316: 5313: 5309: 5306: 5304: 5301: 5300: 5298: 5294: 5287: 5283: 5282: 5280: 5278: 5274: 5271: 5267: 5261: 5258: 5255: 5254: 5251: 5248: 5245: 5241: 5237: 5233: 5230: 5227: 5226: 5224: 5222: 5218: 5212: 5209: 5206: 5205: 5203: 5201: 5197: 5191: 5188: 5185: 5184: 5182: 5180: 5176: 5170: 5167: 5164: 5160: 5156: 5153: 5151: 5148: 5145: 5144: 5142: 5140: 5136: 5130: 5127: 5124: 5123: 5121: 5119: 5115: 5109: 5106: 5104: 5103:Tildrakizumab 5101: 5099: 5096: 5094: 5091: 5089: 5086: 5084: 5081: 5078: 5077: 5074: 5071: 5068: 5067: 5065: 5063: 5059: 5052: 5049: 5046: 5045: 5042: 5039: 5036: 5035: 5033: 5031: 5027: 5021: 5018: 5016: 5013: 5010: 5009: 5006: 5003: 5001: 4998: 4995: 4994: 4992: 4990: 4986: 4979: 4976: 4973: 4972: 4969: 4966: 4964: 4961: 4959: 4956: 4953: 4952: 4950: 4948: 4944: 4938: 4935: 4932: 4931: 4928: 4925: 4923: 4920: 4918: 4915: 4913: 4910: 4907: 4906: 4904: 4902: 4898: 4892: 4889: 4887: 4884: 4882: 4879: 4877: 4874: 4872: 4869: 4867: 4864: 4861: 4860: 4856: 4852: 4848: 4844: 4840: 4836: 4832: 4829: 4826: 4825: 4823: 4821: 4817: 4811: 4808: 4806: 4803: 4800: 4799: 4797: 4795: 4791: 4785: 4782: 4780: 4777: 4775: 4772: 4769: 4768: 4765: 4762: 4760: 4759:Interleukin 4 4757: 4755: 4752: 4750: 4747: 4744: 4743: 4741: 4739: 4735: 4729: 4726: 4724: 4721: 4718: 4717: 4714: 4711: 4709: 4708:Edodekin alfa 4706: 4703: 4702: 4700: 4698: 4694: 4688: 4685: 4683: 4680: 4677: 4676: 4674: 4672: 4668: 4662: 4659: 4657: 4654: 4651: 4650: 4648: 4646: 4642: 4636: 4633: 4630: 4629: 4626: 4625:Interleukin 9 4623: 4620: 4619: 4617: 4615: 4611: 4604: 4600: 4599: 4597: 4595: 4591: 4585: 4584:Interleukin 7 4582: 4579: 4578: 4576: 4574: 4570: 4564: 4561: 4559: 4556: 4554: 4551: 4549: 4546: 4544: 4541: 4539: 4536: 4534: 4531: 4529: 4526: 4524: 4521: 4519: 4516: 4513: 4512: 4509: 4508:Interleukin 6 4506: 4504: 4503:Atexakin alfa 4501: 4498: 4497: 4495: 4493: 4489: 4483: 4480: 4477: 4476: 4473: 4470: 4468: 4465: 4463: 4460: 4457: 4456: 4453: 4450: 4447: 4446: 4443: 4442:Interleukin 5 4440: 4437: 4436: 4434: 4432: 4428: 4422: 4419: 4417: 4414: 4411: 4410: 4407: 4404: 4401: 4400: 4397: 4394: 4392: 4391:Interleukin 4 4389: 4387: 4384: 4381: 4380: 4378: 4376: 4372: 4366: 4363: 4361: 4358: 4356: 4353: 4351: 4348: 4346: 4345:Interleukin 3 4343: 4341: 4338: 4335: 4334: 4332: 4330: 4326: 4320: 4317: 4315: 4312: 4310: 4307: 4304: 4303: 4300: 4297: 4295: 4292: 4290: 4287: 4285: 4284:Interleukin 2 4282: 4280: 4277: 4275: 4272: 4270: 4267: 4265: 4262: 4259: 4258: 4256: 4254: 4250: 4244: 4241: 4238: 4237: 4234: 4231: 4229: 4226: 4224: 4221: 4218: 4217: 4214: 4211: 4209: 4206: 4204: 4201: 4199: 4196: 4193: 4192: 4189: 4186: 4184: 4181: 4178: 4174: 4170: 4169:Interleukin 1 4167: 4164: 4163: 4161: 4159: 4155: 4151: 4148: 4141: 4136: 4134: 4129: 4127: 4122: 4121: 4118: 4106: 4103: 4101: 4098: 4096: 4093: 4091: 4088: 4086: 4083: 4081: 4078: 4076: 4073: 4071: 4068: 4066: 4063: 4061: 4058: 4056: 4053: 4051: 4048: 4046: 4043: 4041: 4038: 4036: 4033: 4031: 4028: 4026: 4023: 4021: 4018: 4016: 4013: 4011: 4008: 4006: 4003: 4001: 3998: 3996: 3993: 3991: 3988: 3986: 3983: 3981: 3978: 3976: 3973: 3971: 3968: 3966: 3963: 3961: 3958: 3956: 3953: 3951: 3948: 3946: 3943: 3941: 3938: 3936: 3933: 3931: 3928: 3926: 3923: 3922: 3920: 3916: 3910: 3907: 3905: 3902: 3900: 3897: 3895: 3892: 3890: 3887: 3885: 3882: 3880: 3877: 3875: 3872: 3870: 3867: 3865: 3862: 3860: 3857: 3855: 3852: 3850: 3847: 3845: 3842: 3840: 3837: 3835: 3832: 3830: 3827: 3825: 3822: 3820: 3817: 3815: 3812: 3810: 3807: 3805: 3802: 3800: 3797: 3795: 3792: 3790: 3787: 3785: 3782: 3780: 3777: 3775: 3772: 3770: 3767: 3765: 3762: 3760: 3757: 3755: 3752: 3750: 3747: 3745: 3742: 3740: 3737: 3735: 3732: 3730: 3727: 3725: 3722: 3720: 3717: 3716: 3714: 3710: 3704: 3701: 3699: 3695: 3692: 3690: 3687: 3685: 3682: 3680: 3677: 3675: 3672: 3670: 3667: 3665: 3662: 3660: 3657: 3655: 3652: 3650: 3647: 3643: 3640: 3638: 3635: 3634: 3633: 3630: 3628: 3625: 3623: 3620: 3618: 3615: 3613: 3610: 3608: 3605: 3603: 3600: 3598: 3595: 3593: 3590: 3588: 3585: 3583: 3580: 3578: 3575: 3573: 3570: 3568: 3565: 3562: 3559: 3557: 3553: 3550: 3548: 3545: 3541: 3538: 3536: 3533: 3532: 3531: 3528: 3526: 3523: 3519: 3516: 3514: 3511: 3510: 3509: 3506: 3504: 3501: 3499: 3496: 3494: 3491: 3489: 3486: 3484: 3481: 3479: 3476: 3474: 3471: 3469: 3466: 3465: 3463: 3459: 3453: 3450: 3448: 3445: 3443: 3440: 3438: 3435: 3433: 3430: 3428: 3425: 3423: 3420: 3418: 3415: 3413: 3410: 3408: 3405: 3403: 3400: 3398: 3395: 3393: 3390: 3388: 3385: 3383: 3380: 3378: 3375: 3373: 3370: 3366: 3363: 3361: 3358: 3357: 3356: 3353: 3351: 3348: 3346: 3343: 3341: 3338: 3334: 3331: 3329: 3326: 3324: 3321: 3320: 3319: 3316: 3314: 3311: 3309: 3306: 3304: 3301: 3299: 3296: 3292: 3289: 3287: 3284: 3283: 3282: 3279: 3277: 3274: 3272: 3269: 3267: 3264: 3262: 3259: 3257: 3254: 3252: 3249: 3245: 3242: 3240: 3237: 3236: 3235: 3232: 3229: 3226: 3224: 3221: 3219: 3216: 3214: 3211: 3209: 3205: 3202: 3200: 3197: 3193: 3190: 3188: 3185: 3183: 3180: 3179: 3178: 3175: 3173: 3170: 3168: 3165: 3163: 3160: 3158: 3155: 3153: 3150: 3149: 3147: 3143: 3137: 3134: 3132: 3129: 3127: 3124: 3122: 3119: 3117: 3114: 3112: 3109: 3107: 3104: 3102: 3099: 3097: 3094: 3092: 3089: 3087: 3084: 3082: 3079: 3077: 3074: 3072: 3069: 3067: 3064: 3062: 3059: 3057: 3054: 3052: 3049: 3047: 3044: 3042: 3039: 3037: 3034: 3032: 3029: 3027: 3024: 3022: 3019: 3017: 3014: 3010: 3007: 3005: 3002: 3001: 3000: 2997: 2993: 2990: 2988: 2985: 2984: 2983: 2980: 2978: 2975: 2973: 2970: 2968: 2965: 2963: 2960: 2958: 2955: 2953: 2950: 2948: 2945: 2943: 2940: 2938: 2935: 2933: 2930: 2928: 2925: 2923: 2920: 2916: 2913: 2911: 2908: 2907: 2906: 2903: 2901: 2898: 2896: 2893: 2891: 2888: 2886: 2883: 2881: 2878: 2876: 2873: 2872: 2870: 2866: 2860: 2857: 2855: 2852: 2850: 2847: 2845: 2842: 2840: 2837: 2835: 2832: 2830: 2827: 2825: 2822: 2820: 2816: 2813: 2811: 2808: 2806: 2803: 2801: 2798: 2796: 2793: 2791: 2788: 2784: 2781: 2779: 2776: 2774: 2771: 2769: 2766: 2764: 2761: 2759: 2756: 2755: 2754: 2751: 2749: 2746: 2744: 2741: 2739: 2736: 2734: 2731: 2729: 2726: 2722: 2719: 2717: 2714: 2713: 2712: 2709: 2707: 2704: 2702: 2699: 2697: 2694: 2692: 2689: 2687: 2684: 2682: 2679: 2677: 2674: 2672: 2669: 2665: 2662: 2660: 2657: 2655: 2652: 2650: 2647: 2645: 2642: 2640: 2637: 2636: 2635: 2632: 2628: 2625: 2623: 2620: 2618: 2615: 2614: 2613: 2610: 2608: 2605: 2601: 2598: 2596: 2593: 2591: 2588: 2587: 2586: 2583: 2581: 2578: 2576: 2573: 2571: 2568: 2566: 2563: 2561: 2558: 2556: 2553: 2551: 2548: 2546: 2543: 2541: 2538: 2536: 2533: 2532: 2530: 2526: 2520: 2517: 2513: 2510: 2508: 2505: 2503: 2500: 2498: 2495: 2493: 2490: 2488: 2485: 2484: 2483: 2480: 2478: 2475: 2473: 2470: 2468: 2465: 2463: 2460: 2458: 2455: 2453: 2450: 2446: 2443: 2441: 2438: 2436: 2433: 2431: 2428: 2427: 2426: 2423: 2421: 2418: 2416: 2413: 2411: 2408: 2406: 2403: 2401: 2398: 2396: 2393: 2391: 2388: 2386: 2383: 2381: 2378: 2374: 2371: 2369: 2366: 2365: 2364: 2361: 2359: 2356: 2354: 2351: 2349: 2346: 2344: 2341: 2339: 2336: 2334: 2331: 2329: 2326: 2324: 2321: 2319: 2316: 2314: 2311: 2309: 2306: 2304: 2301: 2299: 2296: 2294: 2291: 2287: 2284: 2282: 2279: 2278: 2277: 2274: 2272: 2269: 2267: 2264: 2262: 2259: 2255: 2252: 2250: 2247: 2245: 2242: 2240: 2237: 2236: 2235: 2232: 2230: 2227: 2225: 2222: 2218: 2215: 2214: 2213: 2210: 2208: 2205: 2203: 2200: 2198: 2195: 2193: 2190: 2186: 2183: 2181: 2178: 2176: 2173: 2172: 2171: 2168: 2166: 2163: 2159: 2156: 2154: 2151: 2149: 2146: 2144: 2141: 2139: 2136: 2135: 2134: 2131: 2130: 2128: 2124: 2119: 2115: 2111: 2104: 2099: 2097: 2092: 2090: 2085: 2084: 2081: 2077: 2076: 2074: 2073:public domain 2070: 2060: 2056: 2055: 2050: 2046: 2042: 2039: 2035: 2032: 2031: 2027: 2020: 2016: 2012: 2008: 2002: 1998: 1994: 1990: 1986: 1981: 1976: 1972: 1968: 1964: 1959: 1955: 1951: 1946: 1941: 1937: 1933: 1929: 1924: 1920: 1916: 1912: 1908: 1904: 1900: 1897:(1): 99–106. 1896: 1892: 1887: 1883: 1879: 1874: 1869: 1865: 1861: 1857: 1852: 1848: 1844: 1839: 1834: 1830: 1826: 1823:(3): 179–87. 1822: 1818: 1814: 1809: 1805: 1801: 1797: 1793: 1789: 1785: 1781: 1777: 1773: 1769: 1764: 1760: 1756: 1751: 1746: 1742: 1738: 1734: 1729: 1725: 1721: 1718:(9): 2851–5. 1717: 1713: 1707: 1703: 1699: 1694: 1689: 1685: 1681: 1677: 1672: 1668: 1664: 1659: 1654: 1650: 1646: 1642: 1637: 1633: 1629: 1625: 1621: 1617: 1613: 1609: 1605: 1600: 1596: 1592: 1588: 1584: 1580: 1576: 1572: 1568: 1562: 1558: 1554: 1550: 1546: 1542: 1538: 1533: 1529: 1525: 1521: 1517: 1513: 1509: 1505: 1501: 1495: 1491: 1487: 1482: 1477: 1473: 1469: 1465: 1460: 1456: 1452: 1447: 1442: 1438: 1434: 1430: 1425: 1421: 1417: 1412: 1407: 1404:(4): 858–65. 1403: 1399: 1395: 1390: 1389: 1384: 1375: 1371: 1367: 1363: 1359: 1352: 1349: 1344: 1340: 1335: 1330: 1326: 1322: 1318: 1314: 1310: 1306: 1302: 1294: 1291: 1286: 1282: 1278: 1274: 1269: 1264: 1260: 1256: 1252: 1245: 1242: 1237: 1233: 1228: 1223: 1219: 1215: 1211: 1204: 1201: 1196: 1190: 1188: 1184: 1179: 1175: 1169: 1166: 1161: 1157: 1151: 1148: 1144: 1140: 1135: 1133: 1131: 1127: 1123: 1119: 1114: 1112: 1110: 1106: 1099: 1095: 1092: 1091: 1087: 1085: 1079: 1077: 1075: 1071: 1067: 1063: 1055: 1053: 1051: 1048: 1044: 1040: 1036: 1032: 1020: 1015: 1011: 1007: 1004: 1000: 993: 991: 988: 984: 980: 976: 973: 969: 965: 958: 956: 952: 946: 942: 939: 933: 931: 925: 921: 918: 914: 907: 905: 901: 895: 891: 888: 882: 880: 874: 870: 867: 865:RefSeq (mRNA) 863: 856: 855: 850: 846: 843: 837: 836: 831: 827: 824: 822: 818: 811: 810: 805: 801: 798: 792: 791: 786: 782: 779: 777: 773: 766: 765: 760: 756: 753: 747: 746: 741: 737: 734: 732: 728: 725: 722: 720: 717: 713: 710: 706: 702: 695: 691: 686: 680: 677: 675: 672: 670: 667: 665: 662: 661: 659: 656: 655: 649: 646: 644: 641: 639: 636: 634: 631: 629: 626: 624: 621: 620: 618: 615: 614: 608: 605: 603: 600: 598: 595: 593: 590: 589: 587: 584: 583: 580: 579:Gene ontology 576: 572: 560: 555: 551: 546: 543: 541: 537: 529: 524: 513: 509: 505: 501: 497: 493: 489: 485: 481: 477: 476: 473: 469: 464: 461: 451: 447: 443: 439: 435: 431: 427: 423: 419: 415: 414: 411: 407: 402: 399: 398: 395: 393: 389: 387: 386: 382: 381: 378: 376: 372: 368: 364: 360: 352: 347: 343: 339: 334: 324: 320: 313: 306: 300: 293: 285: 281: 277: 272: 268: 263: 259: 251: 246: 242: 238: 233: 223: 219: 212: 205: 199: 192: 188: 182: 178: 174: 169: 165: 160: 156: 152: 148: 144: 140: 136: 132: 128: 124: 120: 116: 108: 103: 96: 91: 86: 75: 73: 67: 62: 59: 58: 54: 51: 44: 40: 35: 31: 27: 22: 16: 5413:expanding it 5402: 5367: 5355:M-CSFR/CSF1R 5342:heterodimer) 5328:heterodimer) 5257:Antagonists: 5256: 5228: 5207: 5186: 5146: 5125: 5098:Risankizumab 5079: 5069: 5047: 5037: 5020:NNC0114-0006 5015:NNC0114-0005 5011: 4996: 4974: 4954: 4933: 4908: 4862: 4827: 4801: 4784:Tralokinumab 4779:Lebrikizumab 4774:Anrukinzumab 4770: 4745: 4719: 4704: 4678: 4652: 4631: 4621: 4580: 4523:Clazakizumab 4514: 4499: 4478: 4462:Benralizumab 4458: 4449:Antagonists: 4448: 4438: 4421:Pascolizumab 4412: 4403:Antagonists: 4402: 4382: 4336: 4305: 4260: 4239: 4219: 4195:Antagonists: 4194: 4165: 3631: 3551: 3539: 3529: 3507: 3354: 3317: 3280: 3233: 3203: 3176: 2998: 2904: 2752: 2481: 2233: 2066: 2064: 2052: 2010: 2006: 1970: 1966: 1935: 1931: 1894: 1890: 1863: 1859: 1820: 1816: 1774:(1): 207–9. 1771: 1767: 1740: 1736: 1715: 1711: 1683: 1679: 1648: 1644: 1607: 1603: 1570: 1566: 1543:(1): 141–5. 1540: 1536: 1506:(4): 971–8. 1503: 1499: 1471: 1467: 1436: 1432: 1401: 1397: 1365: 1361: 1351: 1308: 1304: 1293: 1258: 1254: 1244: 1217: 1213: 1203: 1177: 1168: 1159: 1150: 1083: 1059: 1046: 1034: 1030: 1029: 951:NP_001292988 948: 927: 904:NM_001306059 897: 876: 852: 833: 807: 788: 762: 743: 723: 718: 506:aortic valve 482:pineal gland 478:cumulus cell 428:right testis 390: 383: 349:146,212,188 336:146,166,472 248:115,019,977 235:115,003,975 110:External IDs 69: 15: 5108:Ustekinumab 5088:Briakinumab 5080:Antibodies: 5051:Fezakinumab 5048:Antibodies: 5012:Antibodies: 5000:Denenicokin 4975:Antibodies: 4912:Iboctadekin 4891:Vunakizumab 4886:Secukinumab 4876:Perakizumab 4863:Antibodies: 4771:Antibodies: 4728:Ustekinumab 4723:Briakinumab 4720:Antibodies: 4632:Antibodies: 4558:Tocilizumab 4528:Elsilimomab 4515:Antibodies: 4467:Mepolizumab 4459:Antibodies: 4413:Antibodies: 4340:Daniplestim 4309:Basiliximab 4306:Antibodies: 4274:Celmoleukin 4269:Aldesleukin 4233:Lutikizumab 4228:Gevokizumab 4223:Canakinumab 4220:Antibodies: 1311:(1): 1281. 432:left testis 88:Identifiers 5452:Categories 5163:B (IFN-λ3) 5159:A (IFN-λ2) 5093:Guselkumab 5083:Brazikumab 4978:Fletikumab 4881:Remtolumab 4871:Ixekizumab 4866:Brodalumab 4749:Binetrakin 4687:Oprelvekin 4656:Ilodecakin 4635:Enokizumab 4548:Siltuximab 4538:Olokizumab 4472:Reslizumab 4406:Pitrakinra 4386:Binetrakin 4355:Milodistim 4350:Leridistim 4319:Inolimomab 4294:Teceleukin 4213:Isunakinra 4150:modulators 2116:(see also 1145:, May 2017 1124:, May 2017 1100:References 440:glomerulus 394:(ortholog) 131:HomoloGene 5368:Unsorted: 5229:Agonists: 5208:Agonists: 5187:Agonists: 5147:Agonists: 5126:Agonists: 5070:Agonists: 5038:Agonists: 4997:Agonists: 4955:Agonists: 4927:Tadekinig 4909:Agonists: 4828:Agonists: 4802:Agonists: 4746:Agonists: 4705:Agonists: 4679:Agonists: 4653:Agonists: 4622:Agonists: 4581:Agonists: 4563:Levilimab 4553:Sirukumab 4543:Sarilumab 4500:Agonists: 4439:Agonists: 4416:Dupilumab 4383:Agonists: 4360:Muplestim 4337:Agonists: 4261:Agonists: 4188:Pifonakin 4183:Mobenakin 4166:Agonists: 1595:255357984 955:NP_032382 930:NP_000631 900:NM_008356 879:NM_000640 709:Orthologs 139:GeneCards 5322:IL-22Rα1 5288:instead. 4605:instead. 4533:mAb 1339 4518:ARGX-109 4482:TPI ASM8 4452:YM-90709 4203:Anakinra 4198:AF-12198 2110:Proteins 2019:16981293 1997:70773746 1989:16902988 1954:16751396 1919:38397076 1911:16327802 1882:15870068 1847:12816724 1804:86154739 1796:12485861 1759:12445201 1724:12231526 1702:11786536 1667:11352909 1624:11003391 1537:Genomics 1528:23762963 1420:17030238 1374:10728667 1343:30718742 1285:70773746 1277:16902988 1236:19887609 1141:– 1120:– 1088:See also 1062:IL-13Rα1 1056:Function 1003:Wikidata 688:Sources: 628:membrane 498:gastrula 448:testicle 5340:IL-10Rβ 5336:IL-20Rα 5326:IL-20Rβ 5260:IL-36RA 4805:ALT-803 3918:301–350 3712:251–300 3664:CD240CE 3461:201–250 3145:151–200 2868:101–150 2059:PDBe-KB 2049:UniProt 1838:1920687 1776:Bibcode 1632:9030454 1587:9725226 1557:9177784 1520:9130652 1490:9083087 1455:8663118 1334:6362032 1313:Bibcode 1143:Ensembl 1122:Ensembl 1047:IL13RA2 1043:protein 1035:CD213A2 821:UniProt 776:Ensembl 715:Species 694:QuickGO 369:pattern 143:IL13RA2 127:1277954 102:IL13RA2 95:Aliases 24:IL13RA2 5296:Others 5269:Others 5221:IL1RL2 5200:IL1RL1 4937:IL18BP 4208:IL-1RA 3925:CD300A 3884:CDw293 3669:CD240D 3530:CD213a 3508:CDw210 3473:CD202b 3447:CDw199 3442:CDw198 3096:CD140b 2528:51–100 2054:Q14627 2040:(MeSH) 2017:  1995:  1987:  1967:Cancer 1952:  1917:  1909:  1880:  1845:  1835:  1802:  1794:  1757:  1722:  1700:  1665:  1630:  1622:  1593:  1585:  1555:  1526:  1518:  1488:  1453:  1418:  1372:  1341:  1331:  1283:  1275:  1255:Cancer 1234:  989:search 987:PubMed 854:O88786 835:Q14627 731:Entrez 540:BioGPS 490:uterus 119:300130 5403:This 5179:IL-31 5139:IL-28 5118:IL-27 5062:IL-23 5030:IL-22 4989:IL-21 4947:IL-20 4901:IL-18 4820:IL-17 4794:IL-15 4738:IL-13 4697:IL-12 4671:IL-11 4645:IL-10 4105:CD350 4100:CD349 4095:CD344 4090:CD340 4085:CD339 4080:CD338 4075:CD337 4070:CD336 4065:CD335 4060:CD334 4055:CD333 4050:CD332 4045:CD331 4040:CD329 4035:CD328 4030:CD327 4025:CD326 4020:CD325 4015:CD324 4010:CD322 4005:CD321 4000:CD320 3995:CD318 3990:CD317 3985:CD316 3980:CD315 3975:CD314 3970:CD312 3965:CD309 3960:CD307 3955:CD306 3950:CD305 3945:CD304 3940:CD303 3935:CD302 3930:CD301 3909:CD299 3904:CD298 3899:CD297 3894:CD295 3889:CD294 3879:CD292 3874:CD290 3869:CD289 3864:CD288 3859:CD286 3854:CD284 3849:CD283 3844:CD282 3839:CD281 3834:CD280 3829:CD279 3824:CD278 3819:CD276 3814:CD275 3809:CD274 3804:CD273 3799:CD272 3794:CD271 3789:CD269 3784:CD268 3779:CD267 3774:CD266 3769:CD265 3764:CD264 3759:CD263 3754:CD262 3749:CD261 3744:CD258 3739:CD257 3734:CD256 3729:CD254 3724:CD253 3719:CD252 3703:CD249 3698:CD248 3694:CD247 3689:CD246 3684:CD244 3679:CD243 3674:CD241 3659:CD239 3654:CD238 3649:CD236 3632:CD235 3627:CD234 3622:CD233 3617:CD230 3612:CD229 3607:CD228 3602:CD227 3597:CD226 3592:CD225 3587:CD224 3582:CD223 3577:CD222 3572:CD221 3567:CD220 3552:CD218 3547:CD217 3525:CD212 3503:CD209 3498:CD208 3493:CD207 3488:CD206 3483:CD205 3478:CD204 3468:CD201 3452:CD200 3437:CD197 3432:CD196 3427:CD195 3422:CD194 3417:CD193 3412:CD192 3407:CD191 3402:CD186 3397:CD185 3392:CD184 3387:CD183 3382:CD182 3377:CD181 3372:CD180 3355:CD179 3350:CD178 3345:CD177 3340:CD174 3318:CD172 3313:CD171 3308:CD170 3303:CD169 3298:CD168 3281:CD167 3276:CD166 3271:CD164 3266:CD163 3261:CD162 3256:CD161 3251:CD160 3234:CD159 3204:CD158 3199:CD157 3177:CD156 3172:CD155 3167:CD154 3162:CD153 3157:CD152 3152:CD151 3136:CD150 3131:CD148 3126:CD147 3121:CD146 3116:CD144 3111:CD143 3106:CD142 3101:CD141 3091:CD138 3086:CD137 3081:CD136 3076:CD135 3071:CD134 3066:CD133 3061:CD132 3056:CD131 3051:CD130 3046:CD129 3041:CD127 3036:CD126 3031:CD125 3026:CD124 3021:CD123 3016:CD122 2999:CD121 2982:CD120 2977:CD119 2972:CD118 2967:CD117 2962:CD116 2957:CD115 2952:CD114 2947:CD113 2942:CD112 2937:CD111 2932:CD110 2927:CD109 2922:CD108 2905:CD107 2900:CD106 2895:CD105 2890:CD104 2885:CD103 2880:CD102 2875:CD101 2859:CD100 1993:S2CID 1915:S2CID 1800:S2CID 1628:S2CID 1591:S2CID 1524:S2CID 1281:S2CID 764:16165 724:Mouse 719:Human 690:Amigo 436:gonad 416:sperm 392:Mouse 385:Human 332:Start 267:Mouse 231:Start 164:Human 5409:stub 5286:here 5284:See 4614:IL-9 4603:here 4594:IL-8 4573:IL-7 4492:IL-6 4431:IL-5 4375:IL-4 4329:IL-3 4253:IL-2 4158:IL-1 2854:CD99 2849:CD98 2844:CD97 2839:CD96 2834:CD95 2829:CD94 2824:CD93 2819:CD92 2815:CD91 2810:CD90 2805:CD89 2800:CD88 2795:CD87 2790:CD86 2753:CD85 2748:CD84 2743:CD83 2738:CD82 2733:CD81 2728:CD80 2711:CD79 2706:CD78 2701:CD74 2696:CD73 2691:CD72 2686:CD71 2681:CD70 2676:CD69 2671:CD68 2634:CD66 2612:CD64 2607:CD63 2585:CD62 2580:CD61 2575:CD59 2570:CD58 2565:CD57 2560:CD56 2555:CD55 2550:CD54 2545:CD53 2540:CD52 2535:CD51 2519:CD50 2482:CD49 2477:CD48 2472:CD47 2467:CD46 2462:CD45 2457:CD44 2452:CD43 2425:CD42 2420:CD41 2415:CD40 2410:CD39 2405:CD38 2400:CD37 2395:CD36 2390:CD35 2385:CD34 2380:CD33 2363:CD32 2358:CD31 2353:CD30 2348:CD29 2343:CD28 2338:CD27 2333:CD26 2328:CD25 2323:CD24 2318:CD23 2313:CD22 2308:CD21 2303:CD20 2298:CD19 2293:CD18 2276:CD16 2271:CD15 2266:CD14 2261:CD13 2234:CD11 2229:CD10 2126:1–50 2047:for 2015:PMID 1985:PMID 1950:PMID 1907:PMID 1878:PMID 1843:PMID 1792:PMID 1755:PMID 1720:PMID 1698:PMID 1663:PMID 1620:PMID 1583:PMID 1553:PMID 1516:PMID 1486:PMID 1451:PMID 1416:PMID 1370:PMID 1339:PMID 1273:PMID 1232:PMID 1074:IL-4 1070:IL13 1050:gene 745:3598 375:Bgee 323:Band 284:Chr. 227:Xq23 222:Band 181:Chr. 115:OMIM 72:3LB6 53:RCSB 50:PDBe 5312:CD4 5277:JAK 2224:CD9 2212:CD8 2207:CD7 2202:CD6 2197:CD5 2192:CD4 2170:CD3 2165:CD2 2138:a-c 2133:CD1 2045:PDB 1975:doi 1971:107 1940:doi 1936:176 1899:doi 1868:doi 1864:280 1833:PMC 1825:doi 1784:doi 1772:973 1745:doi 1741:119 1688:doi 1684:277 1653:doi 1649:276 1612:doi 1575:doi 1571:161 1545:doi 1508:doi 1476:doi 1472:272 1441:doi 1437:271 1406:doi 1402:118 1329:PMC 1321:doi 1263:doi 1259:107 1222:doi 494:lip 345:End 244:End 147:OMA 135:534 123:MGI 43:PDB 5454:: 5242:, 5238:, 5161:, 4853:, 4849:, 4845:, 4841:, 4837:, 4175:, 3696:- 2817:- 2158:1E 2153:1D 2148:1B 2143:1A 2112:: 2051:: 2011:33 2009:. 1991:. 1983:. 1969:. 1965:. 1948:. 1934:. 1930:. 1913:. 1905:. 1895:12 1893:. 1876:. 1862:. 1858:. 1841:. 1831:. 1819:. 1815:. 1798:. 1790:. 1782:. 1770:. 1753:. 1739:. 1735:. 1714:. 1696:. 1682:. 1678:. 1661:. 1647:. 1643:. 1626:. 1618:. 1608:51 1606:. 1589:. 1581:. 1569:. 1551:. 1541:42 1539:. 1522:. 1514:. 1504:27 1502:. 1484:. 1470:. 1466:. 1449:. 1435:. 1431:. 1414:. 1400:. 1396:. 1366:60 1364:. 1360:. 1337:. 1327:. 1319:. 1307:. 1303:. 1279:. 1271:. 1257:. 1253:. 1230:. 1218:69 1216:. 1212:. 1186:^ 1176:. 1158:. 1129:^ 1108:^ 1052:. 692:/ 351:bp 338:bp 250:bp 237:bp 145:; 141:: 137:; 133:: 129:; 125:: 121:; 117:: 5440:e 5433:t 5426:v 5415:. 5357:) 5338:/ 5324:/ 5314:) 5246:) 5244:γ 5240:β 5236:α 5234:( 5165:) 5157:( 4857:) 4855:F 4847:D 4843:C 4839:B 4835:A 4833:( 4179:) 4177:β 4173:α 4171:( 4139:e 4132:t 4125:v 3642:b 3637:a 3563:) 3561:b 3556:a 3554:( 3540:2 3535:1 3518:b 3513:a 3365:b 3360:a 3333:g 3328:b 3323:a 3291:b 3286:a 3244:c 3239:a 3230:) 3228:k 3223:i 3218:e 3213:d 3208:a 3206:( 3192:c 3187:b 3182:a 3009:b 3004:a 2992:b 2987:a 2915:b 2910:a 2783:k 2778:j 2773:h 2768:e 2763:d 2758:a 2721:b 2716:a 2664:f 2659:e 2654:d 2649:c 2644:b 2639:a 2627:C 2622:B 2617:A 2600:P 2595:L 2590:E 2512:f 2507:e 2502:d 2497:c 2492:b 2487:a 2445:d 2440:c 2435:b 2430:a 2373:B 2368:A 2286:B 2281:A 2254:d 2249:c 2244:b 2239:a 2217:a 2185:ε 2180:δ 2175:γ 2120:) 2102:e 2095:t 2088:v 2075:. 2061:. 2021:. 1999:. 1977:: 1956:. 1942:: 1921:. 1901:: 1884:. 1870:: 1849:. 1827:: 1821:5 1806:. 1786:: 1778:: 1761:. 1747:: 1726:. 1716:8 1704:. 1690:: 1669:. 1655:: 1634:. 1614:: 1597:. 1577:: 1559:. 1547:: 1530:. 1510:: 1492:. 1478:: 1457:. 1443:: 1422:. 1408:: 1376:. 1345:. 1323:: 1315:: 1309:9 1287:. 1265:: 1238:. 1224:: 1197:. 1180:. 1162:. 1037:( 269:) 166:) 149::

Index

PDB
PDBe
RCSB
3LB6
Aliases
IL13RA2
OMIM
300130
MGI
1277954
HomoloGene
534
GeneCards
IL13RA2
OMA
IL13RA2 - orthologs
Human
X chromosome (human)
Chr.
X chromosome (human)
X chromosome (human)
Genomic location for IL13RA2
Genomic location for IL13RA2
Band
bp
bp
Mouse
X chromosome (mouse)
Chr.
X chromosome (mouse)

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