Knowledge (XXG)

Integrin beta 5

Source πŸ“

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ITGB5 encodes a subunit of integrin that can interact with several alpha chains to form a variety of integrin heterodimers. It also plays a potential role in intercellular communication during tumor progression and metastasis.
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Niu JK, Zhang WJ, Ye LY, Wu LQ, Zhu GJ, Yang ZH, Grau GE, Lou JN (2007). "The role of adhesion molecules, alpha v beta 3, alpha v beta 5 and their ligands in the tumor cell and endothelial cell adhesion".
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Carriero MV, Del Vecchio S, Capozzoli M, et al. (1999). "Urokinase receptor interacts with alpha(v)beta5 vitronectin receptor, promoting urokinase-dependent cell migration in breast cancer".
2075:"Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the alpha v beta 3 integrin" 2174:"Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells" 2820: 1873:
Pasqualini R, Bodorova J, Ye S, Hemler ME (1993). "A study of the structure, function and distribution of beta 5 integrins using novel anti-beta 5 monoclonal antibodies".
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Zhou M, Graham R, Russell G, Croucher PI (2001). "MDC-9 (ADAM-9/Meltrin gamma) functions as an adhesion molecule by binding the alpha(v)beta(5) integrin".
796: 90: 777: 2813: 2626: 2131:"Enhancement of endothelial cell migration and in vitro tube formation by TAP20, a novel beta 5 integrin-modulating, PKC theta-dependent protein" 1832:"A novel integrin specificity exemplified by binding of the alpha v beta 5 integrin to the basic domain of the HIV Tat protein and vitronectin" 1529:"Differentially expressed genes in autosomal dominant osteopetrosis type II osteoclasts reveal known and novel pathways for osteoclast biology" 2849: 1232: 1214: 2839: 1305:
Eliceiri BP, Puente Xose S, Hood John D, Stupack Dwayne G, Schlaepfer David D, Huang Xiaozhu Z, Sheppard Dean, Cheresh David A (Apr 2002).
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Albert ML, Kim JI, Birge RB (2001). "alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells".
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Rabb H, Barroso-Vicens E, Adams R, et al. (1997). "Alpha-V/beta-3 and alpha-V/beta-5 integrin distribution in neoplastic kidney".
1032: 1039: 231: 1658:"Expression of beta 1, beta 3, beta 4, and beta 5 integrins by human epidermal keratinocytes and non-differentiating keratinocytes" 1291: 2032:"cDNA cloning reveals two mouse beta5 integrin transcripts distinct in cytoplasmic domains as a result of alternative splicing" 1201: 1180: 1197: 153: 128: 1307:"Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling" 1176: 70: 2333: 1114: 1584:
Evans JP (2001). "Fertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilization".
267: 166: 1413:"P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration" 260: 159: 2001:
Memmo LM, McKeown-Longo P (1998). "The alphavbeta5 integrin functions as an endocytic receptor for vitronectin".
1623:"Purification and functional characterization of integrin alpha v beta 5. An adhesion receptor for vitronectin" 841: 78: 1797:"A biochemical characterization of the binding of osteopontin to integrins alpha v beta 1 and alpha v beta 5" 2357: 822: 2786: 2721: 2695: 2690: 2685: 2610: 2600: 2541: 1528: 2546: 2658: 2642: 2573: 1755: 142: 57: 1364:"Alpha v beta 5 integrin-dependent programmed cell death triggered by a peptide mimic of annexin V" 1015: 1007: 986: 982: 978: 944: 923: 919: 915: 2844: 2350: 2307: 2240: 1609: 1561: 102: 1011: 974: 948: 911: 657:
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
2299: 2269: 2232: 2203: 2160: 2117: 2096: 2061: 2018: 1989: 1954: 1925: 1890: 1861: 1818: 1783: 1730: 1687: 1644: 1601: 1553: 1509: 1491: 1450: 1432: 1393: 1385: 1344: 1326: 1273: 505: 50: 2790: 2647: 2578: 2508: 2503: 2457: 2291: 2261: 2224: 2193: 2185: 2150: 2142: 2086: 2051: 2043: 2010: 1979: 1946: 1915: 1882: 1851: 1843: 1808: 1773: 1763: 1720: 1712: 1677: 1669: 1634: 1593: 1543: 1499: 1481: 1470:"Integrin Beta 5 Is a Prognostic Biomarker and Potential Therapeutic Target in Glioblastoma" 1440: 1424: 1375: 1334: 1318: 1263: 347: 278: 222: 177: 1744:"Cloning of an integrin beta subunit exhibiting high homology with integrin beta 3 subunit" 512: 98: 2337: 322: 1968:"Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit" 1759: 2742: 2737: 2716: 2198: 2173: 2155: 2130: 2056: 2031: 1856: 1831: 1716: 1682: 1657: 1504: 1469: 1445: 1412: 1339: 1306: 1725: 1700: 1639: 1622: 1380: 1363: 1268: 1251: 711: 706: 701: 696: 691: 686: 681: 676: 671: 666: 661: 656: 651: 646: 630: 625: 620: 615: 610: 605: 600: 595: 590: 585: 569: 564: 559: 554: 2833: 1778: 1743: 1152: 541: 1613: 2311: 2244: 1565: 340: 119: 1701:"Cloning, primary structure and properties of a novel human integrin beta subunit" 82: 2295: 106: 2091: 2074: 1237:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Elevated levels of ITGB5 have been found in patients with autosomal dominant
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Zhang H, Li Zhilun, Viklund Eva-Karin, StrΓΆmblad Staffan (Sep 2002).
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Zhang Ly, Guo Q, Guan Gf, Cheng W, Cheng P, Wu Ah (2019).
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transforming growth factor beta receptor signaling pathway
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Barillari G, Sgadari C, Palladino C, et al. (1999).
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CardΓ³-Vila M, Arap Wadih, Pasqualini Renata (May 2003).
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McLean JW, Vestal DJ, Cheresh DA, Bodary SC (Nov 1990).
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Lafrenie RM, Wahl LM, Epstein JS, et al. (1996).
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Cirulli V, Beattie GM, Klier G, et al. (2000).
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Vogel BE, Lee SJ, Hildebrand A, et al. (1993).
1252:"cDNA sequence of the human integrin beta 5 subunit" 2730: 2678: 2619: 2593: 2566: 2534: 2527: 2476: 2380: 1621:Smith JW, Vestal DJ, Irwin SV, et al. (1990). 1000: 967: 937: 904: 1193: 1191: 1189: 1172: 1170: 1168: 277: 176: 29:Protein-coding gene in the species Homo sapiens 1795:Hu DD, Lin EC, Kovach NL, et al. (1995). 1198:GRCm38: Ensembl release 89: ENSMUSG00000022817 2814: 2358: 8: 1177:GRCh38: Ensembl release 89: ENSG00000082781 61:, Integrin, beta 5, integrin subunit beta 5 2821: 2807: 2531: 2365: 2351: 2343: 737: 537: 318: 217: 114: 2197: 2154: 2090: 2055: 1983: 1919: 1855: 1812: 1777: 1767: 1724: 1681: 1638: 1547: 1503: 1485: 1444: 1379: 1338: 1267: 1742:Suzuki S, Huang ZS, Tanihara H (1990). 1164: 31: 1292:"Entrez Gene: ITGB5 integrin, beta 5" 282: 243: 238: 181: 140: 135: 7: 2775: 2773: 1113:Integrin, beta 5 has been shown to 682:integrin-mediated signaling pathway 2793:. You can help Knowledge (XXG) by 2760:cell surface receptor deficiencies 1717:10.1002/j.1460-2075.1990.tb08275.x 1155:type II, a rare disease of bones. 997: 964: 934: 901: 877: 858: 832: 813: 787: 768: 712:cell adhesion mediated by integrin 500: 418: 356: 335: 25: 1098:that in humans is encoded by the 662:extracellular matrix organization 2777: 511: 504: 266: 259: 253: 230: 165: 158: 152: 127: 2129:Tang S, Gao Y, Ware JA (1999). 1699:Ramaswamy H, Hemler ME (1990). 652:endodermal cell differentiation 2030:Zhang H, Tan SM, Lu J (1998). 1966:Liliental J, Chang DD (1998). 586:integral component of membrane 522:More reference expression data 484:More reference expression data 1: 2254:Biochem. Biophys. Res. Commun 1640:10.1016/S0021-9258(19)38549-7 1381:10.1016/S1097-2765(03)00138-2 1269:10.1016/S0021-9258(17)44878-2 667:epithelial cell-cell adhesion 626:integrin alphav-beta5 complex 434:tunica media of zone of aorta 251: 150: 2850:Transmembrane receptor stubs 2620:Leukocyte-adhesion receptor: 2296:10.1097/CEJ.0b013e3280145c00 1748:Proc. Natl. Acad. Sci. U.S.A 2840:Genes on human chromosome 3 2679:Very late antigen receptor: 2092:10.4049/jimmunol.163.4.1929 570:signaling receptor activity 372:stromal cell of endometrium 2866: 2772: 1921:10.4049/jimmunol.157.3.974 1656:Adams JC, Watt FM (1991). 1549:10.1038/labinvest.2013.140 687:viral entry into host cell 2755: 1233:"Mouse PubMed Reference:" 1215:"Human PubMed Reference:" 1078: 1073: 1069: 1062: 1046: 1027: 1004: 971: 960: 941: 908: 897: 884: 880: 865: 861: 852: 839: 835: 820: 816: 807: 794: 790: 775: 771: 762: 747: 740: 736: 720: 540: 536: 519: 503: 494: 481: 430: 421: 384:Descending thoracic aorta 368: 359: 329: 321: 317: 300: 287: 250: 229: 220: 216: 199: 186: 149: 126: 117: 113: 68: 65: 55: 48: 43: 39: 34: 1814:10.1074/jbc.270.44.26232 1527:Coudert, AE (Mar 2014). 1040:Chr 16: 33.65 – 33.77 Mb 1033:Chr 3: 124.76 – 124.9 Mb 392:tendon of biceps brachii 2329:Info with links in the 1769:10.1073/pnas.87.14.5354 1487:10.3389/fonc.2019.00904 555:virus receptor activity 458:external carotid artery 2789:-related article is a 2787:transmembrane receptor 2331:Cell Migration Gateway 2266:10.1006/bbrc.2000.4155 2190:10.1083/jcb.150.6.1445 2147:10.1083/jcb.147.5.1073 1985:10.1074/jbc.273.4.2379 404:metanephric glomerulus 388:pancreatic ductal cell 2731:Vitronectin receptor: 2594:Fibronectin receptor: 2547:Glycoprotein IIb/IIIa 2535:Cytoadhesin receptor: 2079:Journal of Immunology 2015:10.1242/jcs.111.4.425 1908:Journal of Immunology 1887:10.1242/jcs.105.1.101 1848:10.1083/jcb.121.2.461 1674:10.1083/jcb.115.3.829 1474:Frontiers in Oncology 1429:10.1083/jcb.200207008 1323:10.1083/jcb.200109079 1142:Clinical significance 672:stress fiber assembly 631:extracellular exosome 470:stroma of bone marrow 376:right coronary artery 245:Chromosome 16 (mouse) 2722:Integrin alpha6beta1 2696:Integrin alpha3beta1 2691:Integrin alpha2beta1 2686:Integrin alpha1beta1 2659:Integrin alphaXbeta2 2643:Macrophage-1 antigen 2611:Integrin alpha5beta1 2606:Integrin alpha4beta1 2601:Integrin alpha2beta1 2574:Macrophage-1 antigen 2567:Fibrinogen receptor: 2542:Integrin alpha6beta4 692:cell-matrix adhesion 400:left coronary artery 143:Chromosome 3 (human) 1760:1990PNAS...87.5354S 2336:2014-12-11 at the 842:ENSMUSG00000022817 647:muscle contraction 640:Biological process 621:phagocytic vesicle 579:Cellular component 548:Molecular function 438:epithelium of lens 2802: 2801: 2767: 2766: 2751: 2750: 2284:Eur J Cancer Prev 2048:10.1042/bj3310631 1951:10.1159/000169032 1598:10.1002/bies.1088 1089: 1088: 1085: 1084: 1058: 1057: 1023: 1022: 994: 993: 956: 955: 931: 930: 893: 892: 874: 873: 848: 847: 829: 828: 803: 802: 784: 783: 732: 731: 532: 531: 528: 527: 490: 489: 477: 476: 415: 414: 313: 312: 212: 211: 107:ITGB5 - orthologs 16:(Redirected from 2857: 2823: 2816: 2809: 2781: 2774: 2532: 2367: 2360: 2353: 2344: 2315: 2277: 2248: 2229:10.1038/35046549 2211: 2201: 2168: 2158: 2125: 2104: 2094: 2069: 2059: 2026: 1997: 1987: 1962: 1933: 1923: 1898: 1869: 1859: 1826: 1816: 1791: 1781: 1771: 1738: 1728: 1695: 1685: 1652: 1642: 1633:(19): 11008–13. 1617: 1570: 1569: 1551: 1533: 1524: 1518: 1517: 1507: 1489: 1465: 1459: 1458: 1448: 1408: 1402: 1401: 1383: 1359: 1353: 1352: 1342: 1302: 1296: 1295: 1288: 1282: 1281: 1271: 1262:(28): 17126–31. 1247: 1241: 1240: 1229: 1223: 1222: 1211: 1205: 1195: 1184: 1174: 1071: 1070: 1042: 1035: 1018: 998: 989: 965: 961:RefSeq (protein) 951: 935: 926: 902: 878: 859: 833: 814: 788: 769: 738: 616:integrin complex 601:receptor complex 565:integrin binding 538: 524: 515: 508: 501: 486: 466:stria vascularis 426: 424:Top expressed in 419: 408:popliteal artery 396:cartilage tissue 364: 362:Top expressed in 357: 336: 319: 309: 296: 285: 270: 263: 257: 246: 234: 218: 208: 195: 184: 169: 162: 156: 145: 131: 115: 109: 60: 53: 32: 21: 18:Integrin, beta 5 2865: 2864: 2860: 2859: 2858: 2856: 2855: 2854: 2830: 2829: 2828: 2827: 2770: 2768: 2763: 2747: 2726: 2674: 2615: 2589: 2562: 2523: 2472: 2376: 2371: 2338:Wayback Machine 2323: 2318: 2280: 2251: 2223:(12): 899–905. 2214: 2171: 2128: 2116:(20): 5307–14. 2107: 2072: 2029: 2000: 1965: 1936: 1901: 1872: 1829: 1807:(44): 26232–8. 1794: 1741: 1698: 1655: 1620: 1583: 1579: 1577:Further reading 1574: 1573: 1531: 1526: 1525: 1521: 1467: 1466: 1462: 1410: 1409: 1405: 1361: 1360: 1356: 1304: 1303: 1299: 1290: 1289: 1285: 1249: 1248: 1244: 1231: 1230: 1226: 1213: 1212: 1208: 1196: 1187: 1175: 1166: 1161: 1149: 1144: 1135: 1111: 1092:Integrin beta-5 1080:View/Edit Mouse 1075:View/Edit Human 1038: 1031: 1028:Location (UCSC) 1014: 1010: 1006: 985: 981: 977: 973: 947: 943: 922: 918: 914: 910: 823:ENSG00000082781 716: 635: 606:plasma membrane 574: 560:protein binding 520: 510: 509: 482: 473: 468: 464: 460: 456: 452: 448: 444: 440: 436: 422: 411: 406: 402: 398: 394: 390: 386: 382: 380:ascending aorta 378: 374: 360: 304: 291: 283: 273: 272: 271: 264: 244: 221:Gene location ( 203: 190: 182: 172: 171: 170: 163: 141: 118:Gene location ( 69: 56: 49: 30: 23: 22: 15: 12: 11: 5: 2863: 2861: 2853: 2852: 2847: 2842: 2832: 2831: 2826: 2825: 2818: 2811: 2803: 2800: 2799: 2782: 2765: 2764: 2756: 2753: 2752: 2749: 2748: 2746: 2745: 2743:Alpha-v beta-5 2740: 2738:Alpha-v beta-3 2734: 2732: 2728: 2727: 2725: 2724: 2719: 2717:Alpha-5 beta-1 2714: 2713: 2712: 2698: 2693: 2688: 2682: 2680: 2676: 2675: 2673: 2672: 2671: 2670: 2656: 2655: 2654: 2640: 2639: 2638: 2623: 2621: 2617: 2616: 2614: 2613: 2608: 2603: 2597: 2595: 2591: 2590: 2588: 2587: 2586: 2585: 2570: 2568: 2564: 2563: 2561: 2560: 2559: 2558: 2544: 2538: 2536: 2529: 2525: 2524: 2522: 2521: 2516: 2511: 2506: 2501: 2496: 2491: 2486: 2480: 2478: 2474: 2473: 2471: 2470: 2465: 2460: 2455: 2450: 2445: 2440: 2435: 2430: 2425: 2420: 2415: 2410: 2405: 2400: 2395: 2390: 2384: 2382: 2378: 2377: 2372: 2370: 2369: 2362: 2355: 2347: 2341: 2340: 2322: 2321:External links 2319: 2317: 2316: 2278: 2249: 2217:Nat. Cell Biol 2212: 2184:(6): 1445–60. 2169: 2141:(5): 1073–84. 2126: 2105: 2085:(4): 1929–35. 2070: 2027: 1998: 1978:(4): 2379–83. 1963: 1939:Am. J. Nephrol 1934: 1899: 1870: 1827: 1792: 1754:(14): 5354–8. 1739: 1696: 1653: 1618: 1580: 1578: 1575: 1572: 1571: 1542:(3): 275–285. 1519: 1460: 1423:(7): 1287–97. 1403: 1374:(5): 1151–62. 1354: 1297: 1283: 1242: 1224: 1206: 1185: 1163: 1162: 1160: 1157: 1148: 1145: 1143: 1140: 1134: 1131: 1110: 1107: 1087: 1086: 1083: 1082: 1077: 1067: 1066: 1060: 1059: 1056: 1055: 1053: 1051: 1044: 1043: 1036: 1029: 1025: 1024: 1021: 1020: 1002: 1001: 995: 992: 991: 969: 968: 962: 958: 957: 954: 953: 939: 938: 932: 929: 928: 906: 905: 899: 895: 894: 891: 890: 882: 881: 875: 872: 871: 863: 862: 856: 850: 849: 846: 845: 837: 836: 830: 827: 826: 818: 817: 811: 805: 804: 801: 800: 792: 791: 785: 782: 781: 773: 772: 766: 760: 759: 754: 749: 745: 744: 734: 733: 730: 729: 718: 717: 715: 714: 709: 707:cell migration 704: 699: 694: 689: 684: 679: 674: 669: 664: 659: 654: 649: 643: 641: 637: 636: 634: 633: 628: 623: 618: 613: 608: 603: 598: 596:focal adhesion 593: 588: 582: 580: 576: 575: 573: 572: 567: 562: 557: 551: 549: 545: 544: 534: 533: 530: 529: 526: 525: 517: 516: 498: 492: 491: 488: 487: 479: 478: 475: 474: 472: 471: 467: 463: 459: 455: 451: 447: 443: 439: 435: 431: 428: 427: 416: 413: 412: 410: 409: 405: 401: 397: 393: 389: 385: 381: 377: 373: 369: 366: 365: 353: 352: 344: 333: 327: 326: 323:RNA expression 315: 314: 311: 310: 302: 298: 297: 289: 286: 281: 275: 274: 265: 258: 252: 248: 247: 242: 236: 235: 227: 226: 214: 213: 210: 209: 201: 197: 196: 188: 185: 180: 174: 173: 164: 157: 151: 147: 146: 139: 133: 132: 124: 123: 111: 110: 67: 63: 62: 54: 46: 45: 41: 40: 37: 36: 28: 24: 14: 13: 10: 9: 6: 4: 3: 2: 2862: 2851: 2848: 2846: 2843: 2841: 2838: 2837: 2835: 2824: 2819: 2817: 2812: 2810: 2805: 2804: 2798: 2796: 2792: 2788: 2783: 2780: 2776: 2771: 2762: 2761: 2754: 2744: 2741: 2739: 2736: 2735: 2733: 2729: 2723: 2720: 2718: 2715: 2711: 2707: 2704: 2703: 2702: 2699: 2697: 2694: 2692: 2689: 2687: 2684: 2683: 2681: 2677: 2669: 2665: 2662: 2661: 2660: 2657: 2653: 2649: 2646: 2645: 2644: 2641: 2637: 2633: 2630: 2629: 2628: 2625: 2624: 2622: 2618: 2612: 2609: 2607: 2604: 2602: 2599: 2598: 2596: 2592: 2584: 2580: 2577: 2576: 2575: 2572: 2571: 2569: 2565: 2557: 2553: 2550: 2549: 2548: 2545: 2543: 2540: 2539: 2537: 2533: 2530: 2526: 2520: 2517: 2515: 2512: 2510: 2507: 2505: 2502: 2500: 2497: 2495: 2492: 2490: 2487: 2485: 2482: 2481: 2479: 2475: 2469: 2466: 2464: 2461: 2459: 2456: 2454: 2451: 2449: 2446: 2444: 2441: 2439: 2436: 2434: 2431: 2429: 2426: 2424: 2421: 2419: 2416: 2414: 2411: 2409: 2406: 2404: 2401: 2399: 2396: 2394: 2391: 2389: 2386: 2385: 2383: 2379: 2375: 2368: 2363: 2361: 2356: 2354: 2349: 2348: 2345: 2339: 2335: 2332: 2328: 2325: 2324: 2320: 2313: 2309: 2305: 2301: 2297: 2293: 2290:(6): 517–27. 2289: 2285: 2279: 2275: 2271: 2267: 2263: 2260:(2): 574–80. 2259: 2255: 2250: 2246: 2242: 2238: 2234: 2230: 2226: 2222: 2218: 2213: 2209: 2205: 2200: 2195: 2191: 2187: 2183: 2179: 2175: 2170: 2166: 2162: 2157: 2152: 2148: 2144: 2140: 2136: 2132: 2127: 2123: 2119: 2115: 2111: 2106: 2102: 2098: 2093: 2088: 2084: 2080: 2076: 2071: 2067: 2063: 2058: 2053: 2049: 2045: 2041: 2037: 2033: 2028: 2024: 2020: 2016: 2012: 2009:(4): 425–33. 2008: 2004: 1999: 1995: 1991: 1986: 1981: 1977: 1973: 1972:J. Biol. Chem 1969: 1964: 1960: 1956: 1952: 1948: 1944: 1940: 1935: 1931: 1927: 1922: 1917: 1913: 1909: 1905: 1900: 1896: 1892: 1888: 1884: 1881:(1): 101–11. 1880: 1876: 1871: 1867: 1863: 1858: 1853: 1849: 1845: 1841: 1837: 1833: 1828: 1824: 1820: 1815: 1810: 1806: 1802: 1801:J. Biol. Chem 1798: 1793: 1789: 1785: 1780: 1775: 1770: 1765: 1761: 1757: 1753: 1749: 1745: 1740: 1736: 1732: 1727: 1722: 1718: 1714: 1711:(5): 1561–8. 1710: 1706: 1702: 1697: 1693: 1689: 1684: 1679: 1675: 1671: 1668:(3): 829–41. 1667: 1663: 1659: 1654: 1650: 1646: 1641: 1636: 1632: 1628: 1627:J. Biol. Chem 1624: 1619: 1615: 1611: 1607: 1603: 1599: 1595: 1592:(7): 628–39. 1591: 1587: 1582: 1581: 1576: 1567: 1563: 1559: 1555: 1550: 1545: 1541: 1537: 1530: 1523: 1520: 1515: 1511: 1506: 1501: 1497: 1493: 1488: 1483: 1479: 1475: 1471: 1464: 1461: 1456: 1452: 1447: 1442: 1438: 1434: 1430: 1426: 1422: 1418: 1414: 1407: 1404: 1399: 1395: 1391: 1387: 1382: 1377: 1373: 1369: 1365: 1358: 1355: 1350: 1346: 1341: 1336: 1332: 1328: 1324: 1320: 1317:(1): 149–60. 1316: 1312: 1308: 1301: 1298: 1293: 1287: 1284: 1279: 1275: 1270: 1265: 1261: 1257: 1253: 1246: 1243: 1238: 1234: 1228: 1225: 1220: 1216: 1210: 1207: 1203: 1199: 1194: 1192: 1190: 1186: 1182: 1178: 1173: 1171: 1169: 1165: 1158: 1156: 1154: 1153:osteopetrosis 1146: 1141: 1139: 1132: 1130: 1128: 1124: 1120: 1116: 1108: 1106: 1104: 1101: 1097: 1093: 1081: 1076: 1072: 1068: 1065: 1061: 1054: 1052: 1049: 1045: 1041: 1037: 1034: 1030: 1026: 1019: 1017: 1013: 1009: 1003: 999: 996: 990: 988: 984: 980: 976: 970: 966: 963: 959: 952: 950: 946: 940: 936: 933: 927: 925: 921: 917: 913: 907: 903: 900: 898:RefSeq (mRNA) 896: 889: 888: 883: 879: 876: 870: 869: 864: 860: 857: 855: 851: 844: 843: 838: 834: 831: 825: 824: 819: 815: 812: 810: 806: 799: 798: 793: 789: 786: 780: 779: 774: 770: 767: 765: 761: 758: 755: 753: 750: 746: 743: 739: 735: 728: 724: 719: 713: 710: 708: 705: 703: 700: 698: 697:viral process 695: 693: 690: 688: 685: 683: 680: 678: 677:cell adhesion 675: 673: 670: 668: 665: 663: 660: 658: 655: 653: 650: 648: 645: 644: 642: 639: 638: 632: 629: 627: 624: 622: 619: 617: 614: 612: 609: 607: 604: 602: 599: 597: 594: 592: 589: 587: 584: 583: 581: 578: 577: 571: 568: 566: 563: 561: 558: 556: 553: 552: 550: 547: 546: 543: 542:Gene ontology 539: 535: 523: 518: 514: 507: 502: 499: 497: 493: 485: 480: 469: 465: 461: 457: 453: 449: 445: 441: 437: 433: 432: 429: 425: 420: 417: 407: 403: 399: 395: 391: 387: 383: 379: 375: 371: 370: 367: 363: 358: 355: 354: 351: 349: 345: 343: 342: 338: 337: 334: 332: 328: 324: 320: 316: 308: 303: 299: 295: 290: 284:16|16 B3 280: 276: 269: 262: 256: 249: 241: 237: 233: 228: 224: 219: 215: 207: 202: 198: 194: 189: 179: 175: 168: 161: 155: 148: 144: 138: 134: 130: 125: 121: 116: 112: 108: 104: 100: 96: 92: 88: 84: 80: 76: 72: 64: 59: 52: 47: 42: 38: 33: 27: 19: 2795:expanding it 2784: 2769: 2757: 2287: 2283: 2257: 2253: 2220: 2216: 2181: 2178:J. Cell Biol 2177: 2138: 2135:J. Cell Biol 2134: 2113: 2109: 2082: 2078: 2042:(2): 631–7. 2039: 2035: 2006: 2002: 1975: 1971: 1945:(5): 402–8. 1942: 1938: 1914:(3): 974–7. 1911: 1907: 1878: 1874: 1842:(2): 461–8. 1839: 1836:J. Cell Biol 1835: 1804: 1800: 1751: 1747: 1708: 1704: 1665: 1662:J. Cell Biol 1661: 1630: 1626: 1589: 1585: 1539: 1535: 1522: 1477: 1473: 1463: 1420: 1417:J. Cell Biol 1416: 1406: 1371: 1367: 1357: 1314: 1311:J. Cell Biol 1310: 1300: 1286: 1259: 1255: 1245: 1236: 1227: 1218: 1209: 1150: 1136: 1112: 1109:Interactions 1099: 1091: 1090: 1016:NP_001391992 1008:NP_001139356 1005: 987:NP_001341695 983:NP_001341694 979:NP_001341693 972: 945:NM_001145884 942: 924:NM_001354766 920:NM_001354765 916:NM_001354764 909: 885: 866: 840: 821: 795: 776: 756: 751: 611:cell surface 450:ciliary body 346: 339: 204:124,901,418 191:124,761,948 66:External IDs 26: 2003:J. Cell Sci 1875:J. Cell Sci 1536:Lab. Invest 1256:J Biol Chem 305:33,769,708 292:33,650,035 44:Identifiers 2834:Categories 2110:Cancer Res 2036:Biochem. J 1204:, May 2017 1183:, May 2017 1159:References 1123:Annexin A5 350:(ortholog) 87:HomoloGene 2845:Integrins 2758:see also 2374:Integrins 1586:BioEssays 1496:2234-943X 1437:0021-9525 1390:1097-2765 1368:Mol. Cell 1331:0021-9525 1133:Functions 1012:NP_034710 975:NP_002204 949:NM_010580 912:NM_002213 742:Orthologs 95:GeneCards 2334:Archived 2304:18090124 2274:11162558 2237:11146654 2208:10995448 2165:10579726 2122:10537314 2101:10438928 1614:23712246 1606:11462216 1558:24336069 1514:31616629 1455:12356872 1398:12769841 1349:11927607 1200:– 1179:– 1147:Research 1115:interact 1064:Wikidata 721:Sources: 591:membrane 462:gastrula 446:calvaria 2312:1825380 2245:7535200 2199:2150716 2156:2169340 2066:9531507 2057:1219398 2023:9443892 1994:9442085 1959:8886177 1930:8757599 1895:7689573 1866:7682219 1857:2200091 1823:7592829 1788:2371275 1756:Bibcode 1735:2328726 1692:1918165 1683:2289188 1649:1694173 1566:5097233 1505:6764112 1480:: 904. 1446:2173231 1340:2173263 1278:2211615 1202:Ensembl 1181:Ensembl 1096:protein 854:UniProt 809:Ensembl 748:Species 727:QuickGO 442:decidua 325:pattern 51:Aliases 2552:ITGA2B 2528:Dimers 2310:  2302:  2272:  2243:  2235:  2206:  2196:  2163:  2153:  2120:  2099:  2064:  2054:  2021:  1992:  1957:  1928:  1893:  1864:  1854:  1821:  1786:  1776:  1733:  1726:551850 1723:  1705:EMBO J 1690:  1680:  1647:  1612:  1604:  1564:  1556:  1512:  1502:  1494:  1453:  1443:  1435:  1396:  1388:  1347:  1337:  1329:  1276:  1050:search 1048:PubMed 887:O70309 868:P18084 764:Entrez 496:BioGPS 183:3q21.2 75:147561 2785:This 2706:CD49d 2701:VLA-4 2664:CD11c 2648:CD11b 2632:CD11a 2627:LFA-1 2579:CD11b 2556:ITGB3 2381:Alpha 2327:ITGB5 2308:S2CID 2241:S2CID 1779:54322 1610:S2CID 1562:S2CID 1532:(PDF) 1117:with 1100:ITGB5 1094:is a 797:16419 757:Mouse 752:Human 723:Amigo 454:molar 348:Mouse 341:Human 288:Start 223:Mouse 187:Start 120:Human 99:ITGB5 91:20511 83:96614 58:ITGB5 35:ITGB5 2791:stub 2710:CD29 2668:CD18 2652:CD18 2636:CD18 2583:CD18 2477:Beta 2300:PMID 2270:PMID 2233:PMID 2204:PMID 2161:PMID 2118:PMID 2097:PMID 2062:PMID 2019:PMID 1990:PMID 1955:PMID 1926:PMID 1891:PMID 1862:PMID 1819:PMID 1784:PMID 1731:PMID 1688:PMID 1645:PMID 1602:PMID 1554:PMID 1510:PMID 1492:ISSN 1451:PMID 1433:ISSN 1394:PMID 1386:ISSN 1345:PMID 1327:ISSN 1274:PMID 1127:PAK4 1125:and 1119:PTK2 1103:gene 778:3693 331:Bgee 279:Band 240:Chr. 178:Band 137:Chr. 71:OMIM 2438:A11 2433:A10 2292:doi 2262:doi 2258:280 2225:doi 2194:PMC 2186:doi 2182:150 2151:PMC 2143:doi 2139:147 2087:doi 2083:163 2052:PMC 2044:doi 2040:331 2011:doi 2007:111 1980:doi 1976:273 1947:doi 1916:doi 1912:157 1883:doi 1879:105 1852:PMC 1844:doi 1840:121 1809:doi 1805:270 1774:PMC 1764:doi 1721:PMC 1713:doi 1678:PMC 1670:doi 1666:115 1635:doi 1631:265 1594:doi 1544:doi 1500:PMC 1482:doi 1441:PMC 1425:doi 1421:158 1376:doi 1335:PMC 1319:doi 1315:157 1264:doi 1260:265 301:End 200:End 103:OMA 79:MGI 2836:: 2519:B8 2514:B7 2509:B6 2504:B5 2499:B4 2494:B3 2489:B2 2484:B1 2468:AX 2463:AV 2458:AM 2453:AL 2448:AE 2443:AD 2428:A9 2423:A8 2418:A7 2413:A6 2408:A5 2403:A4 2398:A3 2393:A2 2388:A1 2306:. 2298:. 2288:16 2286:. 2268:. 2256:. 2239:. 2231:. 2219:. 2202:. 2192:. 2180:. 2176:. 2159:. 2149:. 2137:. 2133:. 2114:59 2112:. 2095:. 2081:. 2077:. 2060:. 2050:. 2038:. 2034:. 2017:. 2005:. 1988:. 1974:. 1970:. 1953:. 1943:16 1941:. 1924:. 1910:. 1906:. 1889:. 1877:. 1860:. 1850:. 1838:. 1834:. 1817:. 1803:. 1799:. 1782:. 1772:. 1762:. 1752:87 1750:. 1746:. 1729:. 1719:. 1707:. 1703:. 1686:. 1676:. 1664:. 1660:. 1643:. 1629:. 1625:. 1608:. 1600:. 1590:23 1588:. 1560:. 1552:. 1540:94 1538:. 1534:. 1508:. 1498:. 1490:. 1476:. 1472:. 1449:. 1439:. 1431:. 1419:. 1415:. 1392:. 1384:. 1372:11 1370:. 1366:. 1343:. 1333:. 1325:. 1313:. 1309:. 1272:. 1258:. 1254:. 1235:. 1217:. 1188:^ 1167:^ 1129:. 1121:, 1105:. 725:/ 307:bp 294:bp 206:bp 193:bp 101:; 97:: 93:; 89:: 85:; 81:: 77:; 73:: 2822:e 2815:t 2808:v 2797:. 2708:+ 2666:+ 2650:+ 2634:+ 2581:+ 2554:+ 2366:e 2359:t 2352:v 2314:. 2294:: 2276:. 2264:: 2247:. 2227:: 2221:2 2210:. 2188:: 2167:. 2145:: 2124:. 2103:. 2089:: 2068:. 2046:: 2025:. 2013:: 1996:. 1982:: 1961:. 1949:: 1932:. 1918:: 1897:. 1885:: 1868:. 1846:: 1825:. 1811:: 1790:. 1766:: 1758:: 1737:. 1715:: 1709:9 1694:. 1672:: 1651:. 1637:: 1616:. 1596:: 1568:. 1546:: 1516:. 1484:: 1478:9 1457:. 1427:: 1400:. 1378:: 1351:. 1321:: 1294:. 1280:. 1266:: 1239:. 1221:. 225:) 122:) 105:: 20:)

Index

Integrin, beta 5
Aliases
ITGB5
OMIM
147561
MGI
96614
HomoloGene
20511
GeneCards
ITGB5
OMA
ITGB5 - orthologs
Human
Chromosome 3 (human)
Chr.
Chromosome 3 (human)
Chromosome 3 (human)
Genomic location for ITGB5
Genomic location for ITGB5
Band
bp
bp
Mouse
Chromosome 16 (mouse)
Chr.
Chromosome 16 (mouse)
Genomic location for ITGB5
Genomic location for ITGB5
Band

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