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307:
29:
628:
Alexandersen P, Toussaint A, Christiansen C, Devogelaer JP, Roux C, Fechtenbaum J, et al. (Ipriflavone
Multicenter European Fracture Study) (March 2001). "Ipriflavone in the treatment of postmenopausal osteoporosis: a randomized controlled trial".
853:
77:
451:
694:
Arjmandi BH, Birnbaum RS, Juma S, Barengolts E, Kukreja SC (January 2000). "The synthetic phytoestrogen, ipriflavone, and estrogen prevent bone loss by different mechanisms".
780:
Melis GB, Paoletti AM, Cagnacci A, Bufalino L, Spinetti A, Gambacciani M, Fioretti P (November 1992). "Lack of any estrogenic effect of ipriflavone in postmenopausal women".
846:
839:
59:
393:
407:
737:
Petilli M, Fiorelli G, Benvenuti S, Frediani U, Gori F, Brandi ML (February 1995). "Interactions between ipriflavone and the estrogen receptor".
664:
Sziklai I, Komora V, Ribári O (1992). "Double-blind study on the effectiveness of a bioflavonoid in the control of tinnitus in otosclerosis".
1122:
573:
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107:
964:
226:
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1342:
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825:
997:
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1363:
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Civitelli R (1997). "In vitro and in vivo effects of ipriflavone on bone formation and bone biomechanics".
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1199:
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in postmenopausal women. It is not used to treat osteoporosis. It slows down the action of the
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1311:
1062:
797:
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711:
673:
646:
602:
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563:
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435:
InChI=1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3
41:
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A double-blind study reveals that ipriflavone might be effective on reducing tinnitus on
329:
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876:
532:
69:
1413:
1272:
1067:
520:
318:
809:
766:
723:
614:
565:
The
Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies
1224:
1184:
1100:
1072:
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863:
536:
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491:
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which may be used to inhibit bone resorption, maintain bone density and to prevent
90:
85:
195:
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63:
20:
715:
650:
523:. However, this is incorrect, as the drug does not bind to or activate the
801:
758:
707:
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1267:
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509:
effective in prevention or treatment of osteoporosis.
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1286:
1233:
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978:
955:
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381:
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539:via mechanisms that are distinct from those of
169:
505:A clinical trial reported in 2001 that it was
1116:
847:
502:(bone-building cells) to build up bone mass.
8:
498:(bone-eroding cells), possibly allowing the
19:
415:CC(C)OC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC=CC=C3
1123:
1109:
1101:
854:
840:
832:
557:
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782:Journal of Endocrinological Investigation
234:
551:
432:
412:
301:
145:
319:
18:
274:
68:
7:
519:Ipriflavone has been described as a
89:
1060:Parathyroid hormone-related protein
254:
185:
14:
353:
27:
440:Key:SFBODOKJTYAUCM-UHFFFAOYSA-N
739:Calcified Tissue International
696:Calcified Tissue International
591:Calcified Tissue International
359:
347:
1:
54:FLI13; 7-Isopropoxyisoflavone
1343:Di-O-methylalpinumisoflavone
1348:4'-methyl-alpinumisoflavone
957:Bone morphogenetic proteins
568:. Springer. pp. 651–.
562:Elks J (14 November 2014).
1441:
337:Chemical and physical data
666:Acta Chirurgica Hungarica
535:women. The drug prevents
448:
423:
403:
136:
26:
1168:O-methylated isoflavones
643:10.1001/jama.285.11.1482
70:International Drug Names
998:Aluminium chlorohydrate
862:Drugs for treatment of
148:7-Isopropoxy-3-phenyl-4
1131:Isoflavones and their
1003:Dual action bone agent
121: Not FDA approved
1364:Anagyroidisoflavone A
708:10.1007/s002230050012
599:10.1007/s002239900378
593:. 61 Suppl 1: S12-4.
986:Resorption inhibitor
1200:5-O-methylgenistein
23:
1008:Strontium ranelate
794:10.1007/BF03347647
751:10.1007/BF00296349
1407:
1406:
1333:Alpinumisoflavone
1326:Pyranoisoflavones
1312:7-O-Methylluteone
1098:
1097:
575:978-1-4757-2085-3
525:estrogen receptor
466:
465:
394:Interactive image
287:CompTox Dashboard
120:
16:Chemical compound
1432:
1378:Pseudobaptigenin
1215:Psi-tectorigenin
1125:
1118:
1111:
1102:
931:Non-nitrogenous
856:
849:
842:
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814:
813:
777:
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728:
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691:
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124:Rx-only in Japan
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970:Eptotermin alfa
965:Dibotermin alfa
951:
945:Tiludronic acid
925:Zoledronic acid
920:Risedronic acid
915:Pamidronic acid
910:Neridronic acid
905:Minodronic acid
900:Incadronic acid
895:Ibandronic acid
890:Alendronic acid
877:Bisphosphonates
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452:(what is this?)
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940:Clodronic acid
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820:External links
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788:(10): 755–61.
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672:(1–2): 101–7.
656:
637:(11): 1482–8.
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533:postmenopausal
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152:-chromen-4-one
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1425:Phenol ethers
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1273:Sophoricoside
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1068:Abaloparatide
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864:bone diseases
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828:at PDR Health
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764:
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748:
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733:
730:
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721:
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542:
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534:
530:
527:and shows no
526:
522:
521:phytoestrogen
517:
515:
510:
508:
503:
501:
497:
493:
489:
486:
482:
479:; brand name
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367:
346:
344:
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320:ECHA InfoCard
316:
308:
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303:DTXSID5040679
300:
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49:
45:
43:
39:
36:Clinical data
34:
30:
25:
1398:
1225:Tectorigenin
1185:Formononetin
1073:Teriparatide
1044:
1029:
1014:
1002:
990:
985:
785:
781:
775:
745:(2): 160–5.
742:
738:
732:
699:
695:
669:
665:
659:
634:
630:
623:
590:
584:
564:
518:
514:otosclerosis
511:
506:
504:
492:osteoporosis
480:
468:
467:
456:
450:
276:ChEMBL165790
149:
108:Legal status
102:Legal status
1420:Isoflavones
1399:Ipriflavone
1357:Derivatives
1338:Barbigerone
1297:Bidwillol A
1290:isoflavones
1175:Biochanin A
1141:Isoflavones
1046:Cathepsin K
1038:Romosozumab
991:Ipriflavone
885:Nitrogenous
826:Ipriflavone
702:(1): 61–5.
531:effects in
516:sufferers.
500:osteoblasts
496:osteoclasts
469:Ipriflavone
377: g·mol
326:100.125.854
132:Identifiers
51:Other names
42:Trade names
21:Ipriflavone
1414:Categories
1288:Prenylated
1278:Tectoridin
1235:Glycosides
1205:Pratensein
1133:glycosides
1080:Calcitonin
1053:Odanacatib
1031:Sclerostin
547:References
529:estrogenic
488:isoflavone
382:3D model (
370:Molar mass
236:80BJ7WN25Z
207:ChemSpider
171:35212-22-7
162:CAS Number
141:IUPAC name
1392:Synthetic
1383:Rotenoids
1317:Wighteone
1302:Derrubone
1258:Mirificin
1190:Glycitein
1180:Calycosin
1154:Genistein
1090:Vitamin D
1063:analogues
1048:inhibitor
1033:inhibitor
1023:Denosumab
1018:inhibitor
541:estrogens
537:bone loss
485:synthetic
64:Drugs.com
1268:Puerarin
1248:Genistin
1210:Prunetin
1195:Irigenin
1149:Daidzein
810:32186052
767:24212438
724:31022310
716:10602847
651:11255425
615:21565791
481:Yambolap
459:(verify)
78:ATC code
46:Yambolap
1373:Irilone
1307:Luteone
1243:Daidzin
1220:Retusin
1085:Calcium
802:1491124
759:7736326
678:1343452
607:9263610
483:) is a
375:280.323
343:Formula
182:PubChem
94:)
88: (
86:M05BX01
1263:Ononin
1253:Iridin
1159:Orobol
808:
800:
765:
757:
722:
714:
676:
649:
613:
605:
572:
408:SMILES
267:ChEMBL
256:D01338
1016:RANKL
979:Other
806:S2CID
763:S2CID
720:S2CID
611:S2CID
428:InChI
384:JSmol
1366:and
798:PMID
755:PMID
712:PMID
674:PMID
647:PMID
631:JAMA
603:PMID
570:ISBN
247:KEGG
227:UNII
216:3616
196:3747
60:AHFS
868:M05
790:doi
747:doi
704:doi
639:doi
635:285
595:doi
507:not
477:JAN
473:INN
292:EPA
186:CID
91:WHO
1416::
804:.
796:.
786:15
784:.
761:.
753:.
743:56
741:.
718:.
710:.
700:66
698:.
686:^
670:33
668:.
645:.
633:.
609:.
601:.
554:^
543:.
475:,
357:16
351:18
117:US
1368:B
1124:e
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1110:v
870:)
866:(
855:e
848:t
841:v
812:.
792::
769:.
749::
726:.
706::
680:.
653:.
641::
617:.
597::
578:.
471:(
386:)
363:3
360:O
354:H
348:C
294:)
290:(
150:H
119::
62:/
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
