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Joachim Lingner

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Feretzaki M, Pospisilova M, Valador Fernandes R, Lunardi T, Krejci L, Lingner J. Rad51-dependent recruitment of TERRA lncRNA to telomeres through R-loops. Nature, Article, in press.
262: 258: 222: 163: 254: 257:(ISREC) in Lausanne, Switzerland, first as a junior group leader in 1997 and became senior group leader in 2002. In 2005 he was appointed as associate professor at 321: 1416: 1431: 1350: 1441: 1192:
Grolimund, Larissa; Aeby, Eric; Hamelin, Romain; Armand, Florence; Chiappe, Diego; Moniatte, Marc; Lingner, Joachim (2013-11-25).
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VanÄŤevska, Aleksandra; Ahmed, Wareed; Pfeiffer, Verena; Feretzaki, Marianna; Boulton, Simon J; Lingner, Joachim (2020-04-01).
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Grolimund, Larissa; Aeby, Eric; Hamelin, Romain; Armand, Florence; Chiappe, Diego; Moniatte, Marc; Lingner, Joachim (2013).
221:(born 1962) is a Swiss molecular biologist. He holds the professorship for life sciences and leads the Lingner Lab at the 1387: 356:
VanÄŤevska, Aleksandra; Ahmed, Wareed; Pfeiffer, Verena; Feretzaki, Marianna; Boulton, Simon J.; Lingner, Joachim (2020).
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Chen, Liuh-Yow; Redon, Sophie; Lingner, Joachim (2012). "The human CST complex is a terminator of telomerase activity".
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Porro, Antonio; Feuerhahn, Sascha; Delafontaine, Julien; Riethman, Harold; Rougemont, Jacques; Lingner, Joachim (2014).
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and homology directed repair. Finally, they developed technologies to uncover the changes that occur in the
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He serves as a member of the scientific advisory board in the Center of Integrative Genomics (CIG) of the
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enzyme that renders cancer cells immortal. The lab discovered that telomeres are transcribed into
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Lingner, J. (1997-04-25). "Reverse Transcriptase Motifs in the Catalytic Subunit of Telomerase".
759: 665: 579: 528: 1272: 1231: 1223: 1174: 1156: 1114: 1065: 1057: 1010: 1002: 947: 898: 890: 835: 794: 751: 743: 657: 622: 571: 520: 483: 440: 387: 329: 1194:"A quantitative telomeric chromatin isolation protocol identifies different telomeric states" 454:"A quantitative telomeric chromatin isolation protocol identifies different telomeric states" 1262: 1213: 1164: 1148: 1104: 1049: 994: 937: 882: 825: 786: 735: 647: 612: 604: 561: 512: 473: 430: 420: 377: 369: 74: 1093:"TERRA-Reinforced Association of LSD1 with MRE11 Promotes Processing of Uncapped Telomeres" 542:"Telomeric Repeat Containing RNA and RNA Surveillance Factors at Mammalian Chromosome Ends" 294: 285:
that enable chromosome stability and that regulate cellular lifespan. They elucidated how
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https://erc.europa.eu/sites/default/files/content/selection_panel/advanced_grant_2008.pdf
1209: 990: 878: 731: 716:"Cloning and expression of the essential gene for poly(A) polymerase from S. cerevisiae" 557: 508: 469: 416: 297:, which in turn regulates the telomeric chromatin structure and telomere maintenance by 1169: 1136: 617: 592: 435: 400: 382: 358:"SMCHD 1 promotes ATM -dependent DNA damage signaling and repair of uncapped telomeres" 357: 1388:
https://erc.europa.eu/sites/default/files/document/file/erc_2018_stg_panel_members.pdf
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Teixeira, M.Teresa; Arneric, Milica; Sperisen, Peter; Lingner, Joachim (2004-04-30).
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Teixeira, M.Teresa; Arneric, Milica; Sperisen, Peter; Lingner, Joachim (April 2004).
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Azzalin, C. M.; Reichenbach, P.; Khoriauli, L.; Giulotto, E.; Lingner, J. (2007).
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Teixeira, M.Teresa; Arneric, Milica; Sperisen, Peter; Lingner, Joachim (2004).
1315: 298: 290: 181: 132: 1227: 1160: 1152: 1061: 1006: 974: 894: 862: 747: 401:"Functional characterization of the TERRA transcriptome at damaged telomeres" 373: 566: 541: 1276: 1235: 1178: 1118: 1069: 1037: 1014: 951: 902: 839: 661: 626: 608: 593:"PRDX1 and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase" 575: 524: 487: 444: 391: 798: 755: 715: 305: 302: 286: 274: 176: 1401: 998: 886: 690: 516: 320:
Lingner obtained the Friedrich Miescher Prize (2002), was elected as an
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The Lingner Lab studies of the structure, function and maintenance of
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Porro, Antonio; Feuerhahn, Sascha; Lingner, Joachim (2014-02-27).
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Lingner, Joachim; Kellermann, Josef; Keller, Walter (1991-12-12).
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Chen, Liuh-Yow; Redon, Sophie; Lingner, Joachim (August 2012).
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Academic staff of the École Polytechnique Fédérale de Lausanne
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Chen, Liuh-Yow; Redon, Sophie; Lingner, Joachim (2012-07-04).
863:"The human CST complex is a terminator of telomerase activity" 328:
advanced investigator award (2008), and is a member of the
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Since 2009, Lingner is a full professor at 8: 89:SAB Center of Integrative Genomics (CIG), 29: 18: 1266: 1217: 1168: 1108: 941: 829: 651: 616: 565: 477: 434: 424: 381: 591:Ahmed, Wareed; Lingner, Joachim (2018). 223:École Polytechnique FĂ©dĂ©rale de Lausanne 164:École Polytechnique FĂ©dĂ©rale de Lausanne 682: 295:telomeric repeat containing RNA (TERRA) 1130: 1128: 211:https://www.epfl.ch/labs/lingner-lab/ 7: 308:during aging and disease including 289:shortening is counteracted by the 233:Lingner obtained his PhD from the 98:starting grant review panel member 14: 247:University of Colorado at Boulder 1365:"Scientific Advisory Committee" 324:member (2005), and received an 243:Howard Hughes Medical Institute 241:in 1992. In 1993 he joined the 1: 1417:21st-century Swiss biologists 1351:"List all members by country" 943:10.1016/S0092-8674(04)00334-4 831:10.1016/S0092-8674(04)00334-4 653:10.1016/s0092-8674(04)00334-4 343:starting grant review panel. 1432:Members of Academia Europaea 1110:10.1016/j.celrep.2014.01.022 791:10.1126/science.276.5312.561 339:, and has been a member of 116:Advanced Investigator Award 44:1962 (age 61–62) 1458: 1442:University of Basel alumni 1402:Website of the Lingner Lab 1268:10.1016/j.diff.2017.12.002 281:complexes at the ends of 202: 122: 28: 16:Swiss molecular biologist 1291:"Awards - Funding - LS²" 1153:10.15252/embj.2019102668 374:10.15252/embj.2019102668 187:TERRA long noncoding RNA 110:Friedrich Miescher Prize 597:Genes & Development 567:10.1126/science.1147182 316:Awards and recognitions 609:10.1101/gad.313460.118 337:University of Lausanne 283:eukaryotic chromosomes 91:University of Lausanne 85:Nucleic Acids Research 1198:Nature Communications 458:Nature Communications 405:Nature Communications 69:Board member of 1210:2013NatCo...4.2848G 1048:(7157): 1001–1002. 999:10.1038/nature11269 991:2012Natur.488..540C 887:10.1038/nature11269 879:2012Natur.488..540C 732:1991Natur.354..496L 558:2007Sci...318..798A 517:10.1038/nature11269 509:2012Natur.488..540C 470:2013NatCo...4.2848G 417:2014NatCo...5.5379P 239:University of Basel 195:Cellular senescence 138:University of Basel 127:Academic background 1219:10.1038/ncomms3848 479:10.1038/ncomms3848 426:10.1038/ncomms6379 985:(7412): 540–544. 873:(7412): 540–544. 785:(5312): 561–567. 726:(6353): 496–498. 603:(9–10): 658–669. 552:(5851): 798–801. 503:(7412): 540–544. 330:Academia Europaea 253:. He then joined 216: 215: 1449: 1390: 1385: 1379: 1378: 1376: 1375: 1361: 1355: 1354: 1347: 1341: 1336: 1330: 1329: 1327: 1326: 1311: 1305: 1304: 1302: 1301: 1287: 1281: 1280: 1270: 1246: 1240: 1239: 1221: 1189: 1183: 1182: 1172: 1141:The EMBO Journal 1132: 1123: 1122: 1112: 1088: 1082: 1081: 1054:10.1038/4481001a 1038:"Damage control" 1033: 1027: 1026: 970: 964: 963: 945: 921: 915: 914: 858: 852: 851: 833: 809: 803: 802: 774: 768: 767: 740:10.1038/354496a0 711: 705: 704: 702: 701: 687: 673: 655: 630: 620: 587: 569: 536: 491: 481: 448: 438: 428: 395: 385: 362:The EMBO Journal 191:Genome stability 33: 19: 1457: 1456: 1452: 1451: 1450: 1448: 1447: 1446: 1407: 1406: 1398: 1393: 1386: 1382: 1373: 1371: 1363: 1362: 1358: 1349: 1348: 1344: 1337: 1333: 1324: 1322: 1316:"Find a Member" 1313: 1312: 1308: 1299: 1297: 1289: 1288: 1284: 1255:Differentiation 1248: 1247: 1243: 1191: 1190: 1186: 1134: 1133: 1126: 1090: 1089: 1085: 1035: 1034: 1030: 972: 971: 967: 923: 922: 918: 860: 859: 855: 811: 810: 806: 776: 775: 771: 713: 712: 708: 699: 697: 689: 688: 684: 680: 633: 590: 539: 494: 451: 398: 355: 349: 318: 271: 231: 219:Joachim Lingner 140: 36: 35:Joachim Lingner 24: 23:Joachim Lingner 17: 12: 11: 5: 1455: 1453: 1445: 1444: 1439: 1434: 1429: 1424: 1419: 1409: 1408: 1405: 1404: 1397: 1396:External links 1394: 1392: 1391: 1380: 1356: 1342: 1331: 1306: 1282: 1241: 1184: 1147:(7): e102668. 1124: 1103:(4): 765–776. 1083: 1028: 965: 936:(3): 323–335. 916: 853: 824:(3): 323–335. 804: 769: 706: 681: 679: 676: 675: 674: 646:(3): 323–335. 631: 588: 537: 492: 449: 396: 368:(7): e102668. 353: 348: 347:Selected works 345: 317: 314: 270: 267: 230: 227: 214: 213: 208: 204: 203: 200: 199: 198: 197: 192: 189: 184: 179: 172: 171:Main interests 168: 167: 161: 157: 156: 151: 147: 146: 142: 141: 135: 129: 128: 124: 123: 120: 119: 118: 117: 111: 106: 102: 101: 100: 99: 93: 87: 82: 77: 70: 66: 65: 60: 56: 55: 50: 46: 45: 42: 38: 37: 34: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 1454: 1443: 1440: 1438: 1435: 1433: 1430: 1428: 1427:Living people 1425: 1423: 1420: 1418: 1415: 1414: 1412: 1403: 1400: 1399: 1395: 1389: 1384: 1381: 1370: 1366: 1360: 1357: 1352: 1346: 1343: 1340: 1335: 1332: 1321: 1317: 1310: 1307: 1296: 1292: 1286: 1283: 1278: 1274: 1269: 1264: 1260: 1256: 1252: 1245: 1242: 1237: 1233: 1229: 1225: 1220: 1215: 1211: 1207: 1203: 1199: 1195: 1188: 1185: 1180: 1176: 1171: 1166: 1162: 1158: 1154: 1150: 1146: 1142: 1138: 1131: 1129: 1125: 1120: 1116: 1111: 1106: 1102: 1098: 1094: 1087: 1084: 1079: 1075: 1071: 1067: 1063: 1059: 1055: 1051: 1047: 1043: 1039: 1032: 1029: 1024: 1020: 1016: 1012: 1008: 1004: 1000: 996: 992: 988: 984: 980: 976: 969: 966: 961: 957: 953: 949: 944: 939: 935: 931: 927: 920: 917: 912: 908: 904: 900: 896: 892: 888: 884: 880: 876: 872: 868: 864: 857: 854: 849: 845: 841: 837: 832: 827: 823: 819: 815: 808: 805: 800: 796: 792: 788: 784: 780: 773: 770: 765: 761: 757: 753: 749: 745: 741: 737: 733: 729: 725: 721: 717: 710: 707: 696: 692: 691:"LINGNER LAB" 686: 683: 677: 671: 667: 663: 659: 654: 649: 645: 641: 637: 632: 628: 624: 619: 614: 610: 606: 602: 598: 594: 589: 585: 581: 577: 573: 568: 563: 559: 555: 551: 547: 543: 538: 534: 530: 526: 522: 518: 514: 510: 506: 502: 498: 493: 489: 485: 480: 475: 471: 467: 463: 459: 455: 450: 446: 442: 437: 432: 427: 422: 418: 414: 410: 406: 402: 397: 393: 389: 384: 379: 375: 371: 367: 363: 359: 354: 351: 350: 346: 344: 342: 338: 333: 331: 327: 323: 315: 313: 311: 307: 304: 300: 296: 292: 288: 284: 280: 279:nucleoprotein 276: 268: 266: 264: 260: 256: 252: 248: 244: 240: 236: 228: 226: 224: 220: 212: 209: 205: 201: 196: 193: 190: 188: 185: 183: 180: 178: 175: 174: 173: 169: 165: 162: 158: 155: 152: 148: 145:Academic work 143: 139: 136: 134: 130: 125: 121: 115: 112: 109: 108: 107: 103: 97: 94: 92: 88: 86: 83: 81: 78: 76: 73: 72: 71: 67: 64: 61: 57: 54: 51: 47: 43: 39: 32: 27: 20: 1383: 1372:. 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Index


Swiss
Cell biology
EMBO Journal
EMBO Reports
Nucleic Acids Research
University of Lausanne
ERC
ERC
Alma mater
University of Basel
Cell biology
École Polytechnique Fédérale de Lausanne
Telomeres
Telomerase
TERRA long noncoding RNA
Cellular senescence
https://www.epfl.ch/labs/lingner-lab/
École Polytechnique Fédérale de Lausanne
Biozentrum
University of Basel
Howard Hughes Medical Institute
University of Colorado at Boulder
Thomas Cech
Swiss Institute for Experimental Cancer Research
EPF Lausanne
EPF Lausanne
telomeres
nucleoprotein
eukaryotic chromosomes

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