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was a single molecule that is replicated at a moving locus (the replicating fork) at which both new DNA strands are being synthesized. Subsequently, it was found that there were in fact two moving forks, traveling simultaneously in opposite directions around the chromosome.
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between 1960 and 1961, and returned there to serve as the director from 1963 to 1968. He remained a staff member at Cold Spring Harbor until 1972, when he was appointed head of the
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In his 1963 paper "The bacterial chromosome and its manner of replication as seen by autoradiography", Cairns demonstrated by
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165:(21 November 1922 – 12 November 2018) was a British physician and molecular biologist who made significant contributions to
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Matters of Life and Death: Perspectives on Public Health, Molecular
Biology, Cancer, and the Prospects for the Human Race
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Matters of Life and Death: Perspectives on Public Health, Molecular
Biology, Cancer, and the Prospects for the Human Race
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205:, Uganda. He returned to Australia to work in the School of Microbiology at the
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436:, 2nd edition, edited by John Cairns, Gunther S. Stent, and James D. Watson".
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221:. After leaving Mill Hill in 1980, he took up a professorship at the
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Cairns, John; Stent, Gunther S.; Watson, James D., eds. (2007).
354:"Hugh John Forster Cairns. 21 November 1922 — 12 November 2018"
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277:(1st edition, 1966; 2nd edition, 1992; 3rd edition, 2007).
273:, Cairns also edited the collection of historical accounts
257:("genius") Fellowship. He is the author of the 1978 book
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2002 paper on
Immortal DNA strand hypothesis (theory)
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Cold Spring Harbor
Laboratory Oral History Collection
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British molecular biologist and physician (1922–2018)
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Biographical
Memoirs of Fellows of the Royal Society
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Walter and Eliza Hall
Institute of Medical Research
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Walter and Eliza Hall
Institute of Medical Research
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90:Molecular genetics, cancer research, public health
209:. Cairns took a sabbatical to research at the
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474:Phage and the Origins of Molecular Biology
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313:. Europa Publications. 1996. p. 246.
275:Phage and the Origins of Molecular Biology
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527:Nature Structural & Molecular Biology
432:Livingston, Katherine (1992). "Review of
189:. He then worked as a virologist at the
352:Samson, Leona D.; Cairns, Will (2023).
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261:(now out of print) and the 1997 book,
207:John Curtin School of Medical Research
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311:The International Who's Who 1996–97
615:Alumni of the University of Oxford
253:. In 1981, John Cairns received a
81:B.A., 1943, B.M., 1946, M.D., 1946
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605:British expatriates in Australia
391:Cairns, John (9 February 2021).
523:"H. John F. Cairns (1922–2018)"
507:A description of the 1963 paper
450:10.1126/science.257.5077.1775.a
223:Harvard School of Public Health
397:. Princeton University Press.
185:Cairns received his M.D. from
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610:British expatriates in Uganda
219:Imperial Cancer Research Fund
211:Cold Spring Harbor Laboratory
144:Imperial Cancer Research Fund
136:Cold Spring Harbor Laboratory
590:Fellows of the Royal Society
580:British molecular biologists
477:(3rd ed.). CSHL Press.
335:"HughCairns | Royal Society"
259:Cancer: Science and Society
251:Fellow of the Royal Society
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417:: CS1 maint: postscript (
540:10.1038/S41594-019-0194-1
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575:Harvard University staff
199:Virus Research Institute
160:Hugh John Forster Cairns
132:Virus Research Institute
130:, Melbourne, Australia;
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249:In 1974 he was elected
370:10.1098/rsbm.2022.0047
225:. He retired in 1991.
255:MacArthur Foundation
195:Melbourne, Australia
78:University of Oxford
585:British geneticists
134:, Entebbe, Uganda;
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167:molecular genetics
148:Harvard University
595:MacArthur Fellows
292:Adaptive mutation
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110:Molecular Biology
96:Scientific career
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570:2018 deaths
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197:and at the
25:John Cairns
559:Categories
320:1857430212
298:References
53:1922-11-21
413:cite book
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364:: 37–62.
238:bacterium
232:that the
215:Mill Hill
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181:Career
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419:link
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
