Knowledge

KCNA2

Source 📝

1170:
contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
258: 235: 132: 157: 2528: 2558: 2543: 509: 2573: 264: 163: 40: 2513: 1169:
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle
1666:
Helbig KL, Hedrich UB, Shinde DN, Krey I, Teichmann AC, Hentschel J, Schubert J, Chamberlin AC, Huether R, Lu HM, Alcaraz WA, Tang S, Jungbluth C, Dugan SL, Vainionpää L, Karle KN, Synofzik M, Schöls L, Schüle R, Lehesjoki AE, Helbig I, Lerche H, Lemke JR (October 2016).
1330:
Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stühmer W, Wang X (December 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels".
1907:
Klocke R, Roberds SL, Tamkun MM, Gronemeier M, Augustin A, Albrecht B, Pongs O, Jockusch H (December 1993). "Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal".
2410:"Signal transduction of physiological concentrations of vasopressin in A7r5 vascular smooth muscle cells. A role for PYK2 and tyrosine phosphorylation of K+ channels in the stimulation of Ca2+ spiking" 3397: 4307: 1862:
Kim E, Niethammer M, Rothschild A, Jan YN, Sheng M (November 1995). "Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases".
2264:
Wade GR, Laurier LG, Preiksaitis HG, Sims SM (October 1999). "Delayed rectifier and Ca(2+)-dependent K(+) currents in human esophagus: roles in regulating muscle contraction".
4042: 3294: 3227: 2527: 271: 170: 2557: 2542: 4837: 872: 93: 2572: 853: 2063:
Kim E, Sheng M (1997). "Differential K+ channel clustering activity of PSD-95 and SAP97, two related membrane-associated putative guanylate kinases".
2371:
Kuryshev YA, Wible BA, Gudz TI, Ramirez AN, Brown AM (July 2001). "KChAP/Kvbeta1.2 interactions and their effects on cardiac Kv channel expression".
2145:"Receptor protein tyrosine phosphatase alpha participates in the m1 muscarinic acetylcholine receptor-dependent regulation of Kv1.2 channel activity" 1488:"Receptor protein tyrosine phosphatase alpha participates in the m1 muscarinic acetylcholine receptor-dependent regulation of Kv1.2 channel activity" 4238: 4221: 4216: 4211: 4206: 4243: 3341: 2613: 1937:
Ramaswami M, Tanouy M, Mathew MK (August 1994). "Facile formation of heteromultimeric potassium channels by expression of cloned human cDNAs".
2492: 1312: 1294: 4857: 4295: 3476: 2295:"Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels" 4193: 3214: 2630: 1080: 257: 3979: 2512: 1087: 2223:"Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K(+) channel function" 234: 1377: 4572: 3571: 3349: 2665: 1281: 1260: 1227: 4594: 1277: 156: 131: 4803: 2714: 1215: 1435:
Eldstrom J, Doerksen KW, Steele DF, Fedida D (November 2002). "N-terminal PDZ-binding domain in Kv1 potassium channels".
1256: 4169: 3081: 73: 4444: 1179: 270: 169: 2622: 2606: 1829:"Isolation of a cDNA clone coding for a putative second potassium channel indicates the existence of a gene family" 263: 162: 4798: 3008: 2485: 2293:
Poliak S, Gollan L, Martinez R, Custer A, Einheber S, Salzer JL, Trimmer JS, Shrager P, Peles E (December 1999).
4788: 3049: 2925: 2464: 2454: 917: 81: 64:, HBK5, HK4, HUKIV, KV1.2, MK2, NGK1, RBK2, EIEE32, potassium voltage-gated channel subfamily A member 2, DEE32 4793: 1721:
Paulmichl M, Nasmith P, Hellmiss R, Reed K, Boyle WA, Nerbonne JM, Peralta EG, Clapham DE (September 1991).
898: 4824: 2816: 2803: 2790: 2770: 2757: 2722: 4862: 2599: 1627:"Tyrosine phosphorylation of Kv1.2 modulates its interaction with the actin-binding protein cortactin" 2697: 2478: 1871: 1787: 1734: 1444: 145: 1995:"Expression and function of voltage-dependent potassium channel genes in human airway smooth muscle" 60: 2591: 2450: 1038: 987: 2460: 4164: 3040: 2687: 2396: 2324: 2252: 2131: 2088: 1895: 1774:
Grissmer S, Dethlefs B, Wasmuth JJ, Goldin AL, Gutman GA, Cahalan MD, Chandy KG (December 1990).
1607: 1468: 1356: 105: 1063: 1042: 1012: 991: 3202: 2431: 2388: 2359: 2316: 2281: 2244: 2209: 2174: 2123: 2080: 2051: 2016: 1981: 1946: 1925: 1887: 1850: 1815: 1762: 1698: 1648: 1599: 1558: 1517: 1460: 1417: 1348: 53: 3971: 2952: 2421: 2380: 2349: 2306: 2273: 2234: 2199: 2164: 2156: 2113: 2072: 2041: 2006: 1971: 1917: 1879: 1840: 1805: 1795: 1752: 1742: 1688: 1680: 1669:"A recurrent mutation in KCNA2 as a novel cause of hereditary spastic paraplegia and ataxia" 1638: 1589: 1548: 1507: 1499: 1452: 1407: 1340: 350: 281: 225: 180: 508: 101: 4507: 2647: 325: 1875: 1791: 1738: 1448: 1378:"Entrez Gene: KCNA2 potassium voltage-gated channel, shaker-related subfamily, member 2" 4303: 2990: 2536:: STRUCTURE OF THE CYTOPLASMIC BETA SUBUNIT-T1 ASSEMBLY OF VOLTAGE-DEPENDENT K CHANNELS 2204: 2187: 2169: 2144: 1693: 1668: 1512: 1487: 1412: 1395: 39: 2311: 2294: 2118: 2101: 1921: 1845: 1828: 1594: 1577: 1456: 787: 782: 777: 772: 767: 762: 757: 752: 747: 742: 737: 732: 716: 711: 706: 701: 696: 691: 686: 681: 676: 671: 666: 661: 656: 651: 646: 641: 636: 631: 626: 621: 616: 611: 606: 601: 585: 580: 575: 570: 565: 560: 555: 550: 4851: 4841: 4257: 3930: 2076: 1960:"Selective interaction of voltage-gated K+ channel beta-subunits with alpha-subunits" 1810: 1775: 1757: 1722: 1537:"Selective interaction of voltage-gated K+ channel beta-subunits with alpha-subunits" 1360: 537: 2384: 2328: 2256: 2135: 2102:"The small GTP-binding protein RhoA regulates a delayed rectifier potassium channel" 2092: 1611: 1578:"The small GTP-binding protein RhoA regulates a delayed rectifier potassium channel" 1472: 4610: 4001: 2400: 1899: 1232: 343: 122: 2277: 85: 109: 4540: 4535: 4530: 4525: 4412: 4251: 2626: 1317:
National Center for Biotechnology Information, U.S. National Library of Medicine
1299:
National Center for Biotechnology Information, U.S. National Library of Medicine
1780:
Proceedings of the National Academy of Sciences of the United States of America
1727:
Proceedings of the National Academy of Sciences of the United States of America
426: 4520: 3886: 3254: 3222: 2239: 2222: 242: 139: 89: 2160: 2011: 1994: 1723:"Cloning and expression of a rat cardiac delayed rectifier potassium channel" 1503: 4605: 4515: 2030:"Normalization and subtraction: two approaches to facilitate gene discovery" 1993:
Adda S, Fleischmann BK, Freedman BD, Yu M, Hay DW, Kotlikoff MI (May 1996).
1976: 1959: 1800: 1747: 1553: 1536: 1203: 817: 486: 364: 309: 296: 208: 195: 97: 2435: 2426: 2409: 2392: 2363: 2354: 2337: 2320: 2285: 2248: 2213: 1702: 1652: 1643: 1626: 1464: 1421: 1352: 2566:: N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119 2551:: N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-131 2178: 2127: 2084: 2055: 2020: 1985: 1950: 1929: 1891: 1854: 1819: 1766: 1603: 1562: 1521: 1127: 1122: 4618: 3966: 2945: 2940: 2935: 2930: 2862: 2857: 2338:"Subunit composition determines Kv1 potassium channel surface expression" 1776:"Expression and chromosomal localization of a lymphocyte K+ channel gene" 1111: 962: 943: 4745: 4502: 4338: 2839: 2834: 2829: 2046: 2029: 1344: 1151: 929: 884: 1684: 4422: 4417: 4151: 4146: 4092: 4087: 3903: 3891: 3881: 3876: 3864: 3859: 3854: 3741: 3736: 3731: 3623: 3559: 3554: 3549: 3544: 3539: 3534: 3529: 3464: 3459: 3449: 3444: 3439: 3390: 3385: 3375: 3370: 3247: 3242: 3237: 3232: 3138: 3133: 3128: 3118: 3113: 3103: 3098: 3028: 3023: 3018: 3013: 2916: 2911: 2906: 2901: 2889: 2884: 2879: 2874: 2783: 2750: 2745: 2740: 2735: 1883: 1195: 1095: 839: 17: 4656: 4587: 4582: 4577: 4494: 4481: 4476: 4471: 4466: 4461: 4456: 4407: 4400: 4395: 4390: 4385: 4380: 4375: 4370: 4365: 4353: 4348: 4343: 4333: 4328: 4323: 4318: 4233: 4177: 4134: 4129: 4124: 4119: 4114: 4109: 4104: 4082: 4077: 4072: 4067: 4062: 4057: 4052: 4033: 4028: 4023: 4018: 4006: 3923: 3918: 3913: 3898: 3836: 3831: 3826: 3817: 3812: 3798: 3793: 3784: 3779: 3774: 3765: 3760: 3751: 3746: 3713: 3708: 3703: 3698: 3689: 3680: 3675: 3670: 3661: 3656: 3651: 3646: 3637: 3632: 3618: 3613: 3608: 3603: 3598: 3588: 3524: 3519: 3514: 3509: 3504: 3499: 3494: 3489: 3454: 3424: 3419: 3414: 3409: 3380: 3329: 3324: 3319: 3314: 3304: 3299: 3279: 3264: 3259: 3174: 3169: 3164: 3159: 3143: 3123: 3108: 3069: 3064: 3059: 3054: 2962: 2957: 2680: 2675: 2670: 1191: 1183: 802: 798: 4736: 4731: 4726: 4716: 4711: 4706: 4696: 4691: 4686: 4681: 4676: 4671: 4666: 4651: 4646: 4641: 4636: 4631: 4626: 4565: 4560: 4555: 4550: 4545: 4451: 4439: 4434: 4429: 4360: 4313: 4277: 4272: 4267: 4262: 3989: 3807: 3365: 2702: 2692: 2581:: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex 1199: 1187: 1158: 77: 4766: 3951: 3197: 2985: 2642: 2595: 2474: 2221:
D'Adamo MC, Imbrici P, Sponcichetti F, Pessia M (August 1999).
517: 4290: 4188: 3309: 3269: 2470: 2143:
Tsai W, Morielli AD, Cachero TG, Peralta EG (January 1999).
1486:
Tsai W, Morielli AD, Cachero TG, Peralta EG (January 1999).
1625:
Hattan D, Nesti E, Cachero TG, Morielli AD (October 2002).
2186:
Coleman SK, Newcombe J, Pryke J, Dolly JO (August 1999).
1394:
Coleman SK, Newcombe J, Pryke J, Dolly JO (August 1999).
333: 1958:
Nakahira K, Shi G, Rhodes KJ, Trimmer JS (March 1996).
1535:
Nakahira K, Shi G, Rhodes KJ, Trimmer JS (March 1996).
768:
regulation of circadian sleep/wake cycle, non-REM sleep
498: 1140:
Potassium voltage-gated channel subfamily A member 2
4779: 4603: 4492: 4288: 4186: 4162: 3964: 3570: 3475: 3340: 3213: 3080: 3039: 3001: 2713: 2658: 1056: 1031: 1005: 980: 2188:"Subunit composition of Kv1 channels in human CNS" 2028:Bonaldo MF, Lennon G, Soares MB (September 1996). 1396:"Subunit composition of Kv1 channels in human CNS" 1273: 1271: 1269: 1252: 1250: 1248: 2100:Cachero TG, Morielli AD, Peralta EG (June 1998). 1576:Cachero TG, Morielli AD, Peralta EG (June 1998). 1214:Mutations in this gene have been associated with 280: 179: 2521:: KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT 2373:American Journal of Physiology. Cell Physiology 1939:Indian Journal of Biochemistry & Biophysics 27:Protein-coding gene in the species Homo sapiens 1389: 1387: 1278:GRCm38: Ensembl release 89: ENSMUSG00000040724 2607: 2486: 8: 581:outward rectifier potassium channel activity 576:delayed rectifier potassium channel activity 1257:GRCh38: Ensembl release 89: ENSG00000177301 4838:United States National Library of Medicine 4776: 4763: 3961: 3948: 3210: 3194: 2998: 2982: 2655: 2639: 2614: 2600: 2592: 2493: 2479: 2471: 2336:Manganas LN, Trimmer JS (September 2000). 813: 717:integral component of presynaptic membrane 533: 321: 220: 117: 2463:at the U.S. National Library of Medicine 2453:at the U.S. National Library of Medicine 2425: 2353: 2310: 2238: 2203: 2168: 2117: 2045: 2010: 1975: 1844: 1809: 1799: 1756: 1746: 1692: 1642: 1593: 1552: 1511: 1411: 738:regulation of ion transmembrane transport 4836:This article incorporates text from the 1372: 1370: 571:voltage-gated potassium channel activity 2508: 1244: 637:voltage-gated potassium channel complex 29: 763:potassium ion transmembrane transport 652:integral component of plasma membrane 285: 246: 241: 184: 143: 138: 7: 2408:Byron KL, Lucchesi PA (March 2002). 3980:Calcium-activated chloride channels 2414:The Journal of Biological Chemistry 2342:The Journal of Biological Chemistry 1999:The Journal of Biological Chemistry 1964:The Journal of Biological Chemistry 1833:The Journal of Biological Chemistry 1631:The Journal of Biological Chemistry 1541:The Journal of Biological Chemistry 748:optic nerve structural organization 3050:Amiloride-sensitive cation channel 2266:The American Journal of Physiology 2205:10.1046/j.1471-4159.1999.0730849.x 1413:10.1046/j.1471-4159.1999.0730849.x 1053: 1028: 1002: 977: 953: 934: 908: 889: 863: 844: 556:voltage-gated ion channel activity 503: 421: 359: 338: 25: 1154:that in humans is encoded by the 383:lateral nuclear group of thalamus 2571: 2556: 2541: 2526: 2511: 733:regulation of dopamine secretion 507: 269: 262: 256: 233: 168: 161: 155: 130: 38: 4573:Voltage-dependent anion channel 2666:Inositol trisphosphate receptor 2385:10.1152/ajpcell.2001.281.1.c290 1228:Voltage-gated potassium channel 778:protein complex oligomerization 4595:General bacterial porin family 627:endoplasmic reticulum membrane 612:integral component of membrane 518:More reference expression data 487:More reference expression data 1: 2312:10.1016/S0896-6273(00)81049-1 2278:10.1152/ajpgi.1999.277.4.g885 2119:10.1016/S0092-8674(00)81212-X 1922:10.1016/S0888-7543(05)80358-1 1846:10.1016/S0021-9258(18)83173-8 1595:10.1016/S0092-8674(00)81212-X 1457:10.1016/S0014-5793(02)03572-X 1216:hereditary spastic paraplegia 254: 153: 2077:10.1016/0028-3908(96)00093-7 602:juxtaparanode region of axon 453:anterior horn of spinal cord 4858:Genes on human chromosome 1 773:protein homooligomerization 657:neuronal cell body membrane 4879: 4014:Chloride Channel Accessory 2623:Membrane transport protein 783:sensory perception of pain 551:potassium channel activity 437:lateral geniculate nucleus 4820: 4775: 4762: 3960: 3947: 3209: 3193: 3009:Epithelial sodium channel 2997: 2981: 2654: 2638: 2506: 2240:10.1096/fasebj.13.11.1335 2192:Journal of Neurochemistry 1400:Journal of Neurochemistry 1313:"Mouse PubMed Reference:" 1295:"Human PubMed Reference:" 1126: 1121: 1117: 1110: 1094: 1088:Chr 3: 107.01 – 107.02 Mb 1081:Chr 1: 110.52 – 110.63 Mb 1075: 1060: 1035: 1024: 1009: 984: 973: 960: 956: 941: 937: 928: 915: 911: 896: 892: 883: 870: 866: 851: 847: 838: 823: 816: 812: 796: 788:neuronal action potential 702:potassium channel complex 536: 532: 515: 506: 497: 484: 457:medial vestibular nucleus 449:medial geniculate nucleus 433: 424: 371: 362: 332: 324: 320: 303: 290: 253: 232: 223: 219: 202: 189: 152: 129: 120: 116: 71: 68: 58: 51: 46: 37: 32: 2926:Cation channels of sperm 2465:Medical Subject Headings 2455:Medical Subject Headings 2012:10.1074/jbc.271.22.13239 1178:KCNA2 has been shown to 2451:Kv1.2+Potassium+Channel 1977:10.1074/jbc.271.12.7084 1827:McKinnon D (May 1989). 1801:10.1073/pnas.87.23.9411 1748:10.1073/pnas.88.17.7892 1554:10.1074/jbc.271.12.7084 1333:Pharmacological Reviews 758:transmembrane transport 753:potassium ion transport 2427:10.1074/jbc.M104726200 2355:10.1074/jbc.M005010200 2161:10.1093/emboj/18.1.109 1644:10.1074/jbc.M205005200 1504:10.1093/emboj/18.1.109 687:lamellipodium membrane 465:deep cerebellar nuclei 399:superior frontal gyrus 287:3 F2.3|3 46.61 cM 3002:Constitutively active 677:endoplasmic reticulum 461:medial dorsal nucleus 391:primary visual cortex 379:middle temporal gyrus 2461:KCNA2+protein,+human 692:presynaptic membrane 561:ion channel activity 473:facial motor nucleus 248:Chromosome 3 (mouse) 146:Chromosome 1 (human) 4769:By gating mechanism 2272:(4 Pt 1): G885–95. 1876:1995Natur.378...85K 1792:1990PNAS...87.9411G 1739:1991PNAS...88.7892P 1673:Annals of Neurology 1449:2002FEBSL.531..529E 4840:, which is in the 4296:TRP cation channel 4194:CNG cation channel 3477:Tandem pore domain 2688:Ryanodine receptor 2047:10.1101/gr.6.9.791 1345:10.1124/pr.57.4.10 918:ENSMUSG00000040724 726:Biological process 707:paranodal junction 595:Cellular component 544:Molecular function 445:lobe of cerebellum 4832: 4831: 4816: 4815: 4812: 4811: 4804:Stretch-activated 4781:Ion channel class 4758: 4757: 4754: 4753: 3943: 3942: 3939: 3938: 3215:Calcium-activated 3203:Potassium channel 3189: 3188: 3185: 3184: 2977: 2976: 2973: 2972: 2589: 2588: 2065:Neuropharmacology 1685:10.1002/ana.24762 1637:(41): 38596–606. 1137: 1136: 1133: 1132: 1106: 1105: 1071: 1070: 1050: 1049: 1020: 1019: 999: 998: 969: 968: 950: 949: 924: 923: 905: 904: 879: 878: 860: 859: 808: 807: 682:neuron projection 528: 527: 524: 523: 493: 492: 480: 479: 469:cerebellar vermis 418: 417: 395:cerebellar vermis 387:postcentral gyrus 316: 315: 215: 214: 110:KCNA2 - orthologs 16:(Redirected from 4870: 4777: 4764: 3972:Chloride channel 3962: 3949: 3342:Inward-rectifier 3211: 3195: 2999: 2983: 2953:Two-pore channel 2656: 2640: 2616: 2609: 2602: 2593: 2575: 2560: 2545: 2530: 2515: 2495: 2488: 2481: 2472: 2439: 2429: 2404: 2367: 2357: 2348:(38): 29685–93. 2332: 2314: 2289: 2260: 2242: 2217: 2207: 2182: 2172: 2149:The EMBO Journal 2139: 2121: 2096: 2059: 2049: 2024: 2014: 2005:(22): 13239–43. 1989: 1979: 1954: 1933: 1903: 1884:10.1038/378085a0 1858: 1848: 1823: 1813: 1803: 1770: 1760: 1750: 1707: 1706: 1696: 1663: 1657: 1656: 1646: 1622: 1616: 1615: 1597: 1573: 1567: 1566: 1556: 1532: 1526: 1525: 1515: 1492:The EMBO Journal 1483: 1477: 1476: 1432: 1426: 1425: 1415: 1391: 1382: 1381: 1374: 1365: 1364: 1327: 1321: 1320: 1309: 1303: 1302: 1291: 1285: 1275: 1264: 1254: 1119: 1118: 1090: 1083: 1066: 1054: 1045: 1029: 1025:RefSeq (protein) 1015: 1003: 994: 978: 954: 935: 909: 890: 864: 845: 814: 534: 520: 511: 504: 489: 429: 427:Top expressed in 422: 411:endothelial cell 407:Brodmann area 46 375:Brodmann area 23 367: 365:Top expressed in 360: 339: 322: 312: 299: 288: 273: 266: 260: 249: 237: 221: 211: 198: 187: 172: 165: 159: 148: 134: 118: 112: 63: 56: 42: 30: 21: 4878: 4877: 4873: 4872: 4871: 4869: 4868: 4867: 4848: 4847: 4833: 4828: 4808: 4771: 4750: 4599: 4498: 4488: 4284: 4182: 4158: 3956: 3935: 3849: 3726: 3583: 3566: 3471: 3435: 3405: 3361: 3353: 3336: 3290: 3205: 3181: 3154: 3093: 3076: 3035: 2993: 2969: 2852: 2824: 2811: 2798: 2778: 2765: 2730: 2709: 2650: 2648:Calcium channel 2634: 2620: 2590: 2585: 2582: 2576: 2567: 2561: 2552: 2546: 2537: 2531: 2522: 2516: 2502: 2499: 2447: 2442: 2420:(9): 7298–307. 2407: 2370: 2335: 2292: 2263: 2233:(11): 1335–45. 2220: 2185: 2142: 2099: 2071:(7): 993–1000. 2062: 2034:Genome Research 2027: 1992: 1957: 1936: 1906: 1861: 1826: 1773: 1720: 1716: 1714:Further reading 1711: 1710: 1665: 1664: 1660: 1624: 1623: 1619: 1575: 1574: 1570: 1534: 1533: 1529: 1485: 1484: 1480: 1434: 1433: 1429: 1393: 1392: 1385: 1376: 1375: 1368: 1329: 1328: 1324: 1311: 1310: 1306: 1293: 1292: 1288: 1276: 1267: 1255: 1246: 1241: 1224: 1212: 1176: 1167: 1147: 1128:View/Edit Mouse 1123:View/Edit Human 1086: 1079: 1076:Location (UCSC) 1062: 1041: 1037: 1011: 990: 986: 899:ENSG00000177301 792: 721: 642:plasma membrane 622:cell projection 590: 586:kinesin binding 566:protein binding 516: 485: 476: 471: 467: 463: 459: 455: 451: 447: 443: 439: 425: 414: 409: 405: 401: 397: 393: 389: 385: 381: 377: 363: 307: 294: 286: 276: 275: 274: 267: 247: 224:Gene location ( 206: 193: 185: 175: 174: 173: 166: 144: 121:Gene location ( 72: 59: 52: 28: 23: 22: 15: 12: 11: 5: 4876: 4874: 4866: 4865: 4860: 4850: 4849: 4830: 4829: 4821: 4818: 4817: 4814: 4813: 4810: 4809: 4807: 4806: 4801: 4796: 4791: 4785: 4783: 4773: 4772: 4767: 4760: 4759: 4756: 4755: 4752: 4751: 4749: 4748: 4743: 4742: 4741: 4740: 4739: 4734: 4729: 4721: 4720: 4719: 4714: 4709: 4701: 4700: 4699: 4694: 4689: 4684: 4679: 4674: 4669: 4661: 4660: 4659: 4654: 4649: 4644: 4639: 4634: 4629: 4615: 4613: 4601: 4600: 4598: 4597: 4592: 4591: 4590: 4585: 4580: 4570: 4569: 4568: 4563: 4558: 4553: 4548: 4543: 4538: 4533: 4528: 4523: 4512: 4510: 4496: 4490: 4489: 4487: 4486: 4485: 4484: 4479: 4474: 4469: 4464: 4459: 4449: 4448: 4447: 4442: 4432: 4427: 4426: 4425: 4420: 4415: 4405: 4404: 4403: 4398: 4393: 4388: 4383: 4378: 4373: 4368: 4358: 4357: 4356: 4351: 4346: 4341: 4336: 4331: 4326: 4321: 4311: 4300: 4298: 4286: 4285: 4283: 4282: 4281: 4280: 4275: 4270: 4265: 4260: 4248: 4247: 4246: 4241: 4236: 4226: 4225: 4224: 4219: 4214: 4209: 4198: 4196: 4184: 4183: 4181: 4180: 4174: 4172: 4170:Proton channel 4160: 4159: 4157: 4156: 4155: 4154: 4149: 4139: 4138: 4137: 4132: 4127: 4122: 4117: 4112: 4107: 4097: 4096: 4095: 4090: 4085: 4080: 4075: 4070: 4065: 4060: 4055: 4045: 4040: 4039: 4038: 4037: 4036: 4031: 4026: 4021: 4011: 4010: 4009: 4004: 3994: 3993: 3992: 3976: 3974: 3958: 3957: 3952: 3945: 3944: 3941: 3940: 3937: 3936: 3934: 3933: 3928: 3927: 3926: 3921: 3916: 3906: 3901: 3896: 3895: 3894: 3889: 3884: 3879: 3869: 3868: 3867: 3862: 3857: 3847: 3842: 3841: 3840: 3839: 3834: 3829: 3822: 3821: 3820: 3815: 3810: 3803: 3802: 3801: 3796: 3789: 3788: 3787: 3782: 3777: 3770: 3769: 3768: 3763: 3756: 3755: 3754: 3749: 3744: 3739: 3734: 3724: 3719: 3718: 3717: 3716: 3711: 3706: 3701: 3694: 3693: 3692: 3685: 3684: 3683: 3678: 3673: 3666: 3665: 3664: 3659: 3654: 3649: 3642: 3641: 3640: 3635: 3628: 3627: 3626: 3621: 3616: 3611: 3606: 3601: 3596: 3591: 3581: 3576: 3574: 3568: 3567: 3565: 3564: 3563: 3562: 3557: 3552: 3547: 3542: 3537: 3532: 3527: 3522: 3517: 3512: 3507: 3502: 3497: 3492: 3481: 3479: 3473: 3472: 3470: 3469: 3468: 3467: 3462: 3457: 3452: 3447: 3442: 3433: 3429: 3428: 3427: 3422: 3417: 3412: 3403: 3395: 3394: 3393: 3388: 3383: 3378: 3373: 3368: 3359: 3355: 3351: 3346: 3344: 3338: 3337: 3335: 3334: 3333: 3332: 3327: 3322: 3317: 3312: 3307: 3302: 3297: 3288: 3284: 3283: 3282: 3274: 3273: 3272: 3267: 3262: 3252: 3251: 3250: 3245: 3240: 3235: 3230: 3219: 3217: 3207: 3206: 3198: 3191: 3190: 3187: 3186: 3183: 3182: 3180: 3179: 3178: 3177: 3172: 3167: 3162: 3152: 3148: 3147: 3146: 3141: 3136: 3131: 3126: 3121: 3116: 3111: 3106: 3101: 3091: 3086: 3084: 3078: 3077: 3075: 3074: 3073: 3072: 3067: 3062: 3057: 3046: 3044: 3037: 3036: 3034: 3033: 3032: 3031: 3026: 3021: 3016: 3005: 3003: 2995: 2994: 2991:Sodium channel 2986: 2979: 2978: 2975: 2974: 2971: 2970: 2968: 2967: 2966: 2965: 2960: 2950: 2949: 2948: 2943: 2938: 2933: 2922: 2921: 2920: 2919: 2914: 2909: 2904: 2894: 2893: 2892: 2887: 2882: 2877: 2867: 2866: 2865: 2860: 2850: 2845: 2844: 2843: 2842: 2837: 2832: 2822: 2814: 2809: 2801: 2796: 2788: 2787: 2786: 2776: 2768: 2763: 2755: 2754: 2753: 2748: 2743: 2738: 2728: 2719: 2717: 2711: 2710: 2708: 2707: 2706: 2705: 2700: 2695: 2685: 2684: 2683: 2678: 2673: 2662: 2660: 2652: 2651: 2643: 2636: 2635: 2621: 2619: 2618: 2611: 2604: 2596: 2587: 2586: 2584: 2583: 2577: 2570: 2568: 2562: 2555: 2553: 2547: 2540: 2538: 2532: 2525: 2523: 2517: 2510: 2507: 2504: 2503: 2500: 2498: 2497: 2490: 2483: 2475: 2469: 2468: 2458: 2446: 2445:External links 2443: 2441: 2440: 2405: 2368: 2333: 2305:(4): 1037–47. 2290: 2261: 2218: 2183: 2140: 2112:(6): 1077–85. 2097: 2060: 2040:(9): 791–806. 2025: 1990: 1970:(12): 7084–9. 1955: 1934: 1904: 1870:(6552): 85–8. 1859: 1839:(14): 8230–6. 1824: 1786:(23): 9411–5. 1771: 1733:(17): 7892–5. 1717: 1715: 1712: 1709: 1708: 1679:(4): 638–642. 1658: 1617: 1588:(6): 1077–85. 1568: 1547:(12): 7084–9. 1527: 1478: 1427: 1383: 1366: 1339:(4): 473–508. 1322: 1304: 1286: 1265: 1243: 1242: 1240: 1237: 1236: 1235: 1230: 1223: 1220: 1211: 1208: 1175: 1172: 1166: 1163: 1145: 1142:also known as 1135: 1134: 1131: 1130: 1125: 1115: 1114: 1108: 1107: 1104: 1103: 1101: 1099: 1092: 1091: 1084: 1077: 1073: 1072: 1069: 1068: 1058: 1057: 1051: 1048: 1047: 1033: 1032: 1026: 1022: 1021: 1018: 1017: 1007: 1006: 1000: 997: 996: 982: 981: 975: 971: 970: 967: 966: 958: 957: 951: 948: 947: 939: 938: 932: 926: 925: 922: 921: 913: 912: 906: 903: 902: 894: 893: 887: 881: 880: 877: 876: 868: 867: 861: 858: 857: 849: 848: 842: 836: 835: 830: 825: 821: 820: 810: 809: 806: 805: 794: 793: 791: 790: 785: 780: 775: 770: 765: 760: 755: 750: 745: 740: 735: 729: 727: 723: 722: 720: 719: 714: 709: 704: 699: 694: 689: 684: 679: 674: 669: 664: 659: 654: 649: 644: 639: 634: 629: 624: 619: 614: 609: 604: 598: 596: 592: 591: 589: 588: 583: 578: 573: 568: 563: 558: 553: 547: 545: 541: 540: 530: 529: 526: 525: 522: 521: 513: 512: 501: 495: 494: 491: 490: 482: 481: 478: 477: 475: 474: 470: 466: 462: 458: 454: 450: 446: 442: 441:pontine nuclei 438: 434: 431: 430: 419: 416: 415: 413: 412: 408: 404: 400: 396: 392: 388: 384: 380: 376: 372: 369: 368: 356: 355: 347: 336: 330: 329: 326:RNA expression 318: 317: 314: 313: 305: 301: 300: 292: 289: 284: 278: 277: 268: 261: 255: 251: 250: 245: 239: 238: 230: 229: 217: 216: 213: 212: 204: 200: 199: 191: 188: 183: 177: 176: 167: 160: 154: 150: 149: 142: 136: 135: 127: 126: 114: 113: 70: 66: 65: 57: 49: 48: 44: 43: 35: 34: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 4875: 4864: 4861: 4859: 4856: 4855: 4853: 4846: 4845: 4843: 4842:public domain 4839: 4827: 4826: 4819: 4805: 4802: 4800: 4799:Voltage-gated 4797: 4795: 4792: 4790: 4787: 4786: 4784: 4782: 4778: 4774: 4770: 4765: 4761: 4747: 4744: 4738: 4735: 4733: 4730: 4728: 4725: 4724: 4722: 4718: 4715: 4713: 4710: 4708: 4705: 4704: 4702: 4698: 4695: 4693: 4690: 4688: 4685: 4683: 4680: 4678: 4675: 4673: 4670: 4668: 4665: 4664: 4662: 4658: 4655: 4653: 4650: 4648: 4645: 4643: 4640: 4638: 4635: 4633: 4630: 4628: 4625: 4624: 4622: 4621: 4620: 4617: 4616: 4614: 4612: 4609: 4607: 4602: 4596: 4593: 4589: 4586: 4584: 4581: 4579: 4576: 4575: 4574: 4571: 4567: 4564: 4562: 4559: 4557: 4554: 4552: 4549: 4547: 4544: 4542: 4539: 4537: 4534: 4532: 4529: 4527: 4524: 4522: 4519: 4518: 4517: 4514: 4513: 4511: 4509: 4506: 4504: 4500: 4491: 4483: 4480: 4478: 4475: 4473: 4470: 4468: 4465: 4463: 4460: 4458: 4455: 4454: 4453: 4450: 4446: 4443: 4441: 4438: 4437: 4436: 4433: 4431: 4428: 4424: 4421: 4419: 4416: 4414: 4411: 4410: 4409: 4406: 4402: 4399: 4397: 4394: 4392: 4389: 4387: 4384: 4382: 4379: 4377: 4374: 4372: 4369: 4367: 4364: 4363: 4362: 4359: 4355: 4352: 4350: 4347: 4345: 4342: 4340: 4337: 4335: 4332: 4330: 4327: 4325: 4322: 4320: 4317: 4316: 4315: 4312: 4309: 4305: 4302: 4301: 4299: 4297: 4294: 4292: 4287: 4279: 4276: 4274: 4271: 4269: 4266: 4264: 4261: 4259: 4256: 4255: 4254: 4253: 4249: 4245: 4242: 4240: 4237: 4235: 4232: 4231: 4230: 4227: 4223: 4220: 4218: 4215: 4213: 4210: 4208: 4205: 4204: 4203: 4200: 4199: 4197: 4195: 4192: 4190: 4185: 4179: 4176: 4175: 4173: 4171: 4168: 4166: 4161: 4153: 4150: 4148: 4145: 4144: 4143: 4140: 4136: 4133: 4131: 4128: 4126: 4123: 4121: 4118: 4116: 4113: 4111: 4108: 4106: 4103: 4102: 4101: 4098: 4094: 4091: 4089: 4086: 4084: 4081: 4079: 4076: 4074: 4071: 4069: 4066: 4064: 4061: 4059: 4056: 4054: 4051: 4050: 4049: 4046: 4044: 4041: 4035: 4032: 4030: 4027: 4025: 4022: 4020: 4017: 4016: 4015: 4012: 4008: 4005: 4003: 4000: 3999: 3998: 3995: 3991: 3988: 3987: 3986: 3983: 3982: 3981: 3978: 3977: 3975: 3973: 3970: 3968: 3963: 3959: 3955: 3954:Miscellaneous 3950: 3946: 3932: 3931:Shaker (gene) 3929: 3925: 3922: 3920: 3917: 3915: 3912: 3911: 3910: 3907: 3905: 3904:minK/ISK-like 3902: 3900: 3897: 3893: 3890: 3888: 3885: 3883: 3880: 3878: 3875: 3874: 3873: 3870: 3866: 3863: 3861: 3858: 3856: 3853: 3852: 3851: 3844: 3843: 3838: 3835: 3833: 3830: 3828: 3825: 3824: 3823: 3819: 3816: 3814: 3811: 3809: 3806: 3805: 3804: 3800: 3797: 3795: 3792: 3791: 3790: 3786: 3783: 3781: 3778: 3776: 3773: 3772: 3771: 3767: 3764: 3762: 3759: 3758: 3757: 3753: 3750: 3748: 3745: 3743: 3740: 3738: 3735: 3733: 3730: 3729: 3728: 3721: 3720: 3715: 3712: 3710: 3707: 3705: 3702: 3700: 3697: 3696: 3695: 3691: 3688: 3687: 3686: 3682: 3679: 3677: 3674: 3672: 3669: 3668: 3667: 3663: 3660: 3658: 3655: 3653: 3650: 3648: 3645: 3644: 3643: 3639: 3636: 3634: 3631: 3630: 3629: 3625: 3622: 3620: 3617: 3615: 3612: 3610: 3607: 3605: 3602: 3600: 3597: 3595: 3592: 3590: 3587: 3586: 3585: 3578: 3577: 3575: 3573: 3572:Voltage-gated 3569: 3561: 3558: 3556: 3553: 3551: 3548: 3546: 3543: 3541: 3538: 3536: 3533: 3531: 3528: 3526: 3523: 3521: 3518: 3516: 3513: 3511: 3508: 3506: 3503: 3501: 3498: 3496: 3493: 3491: 3488: 3487: 3486: 3483: 3482: 3480: 3478: 3474: 3466: 3463: 3461: 3458: 3456: 3453: 3451: 3448: 3446: 3443: 3441: 3438: 3437: 3436: 3430: 3426: 3423: 3421: 3418: 3416: 3413: 3411: 3408: 3407: 3406: 3399: 3396: 3392: 3389: 3387: 3384: 3382: 3379: 3377: 3374: 3372: 3369: 3367: 3364: 3363: 3362: 3356: 3354: 3348: 3347: 3345: 3343: 3339: 3331: 3328: 3326: 3323: 3321: 3318: 3316: 3313: 3311: 3308: 3306: 3303: 3301: 3298: 3296: 3293: 3292: 3291: 3285: 3281: 3278: 3277: 3275: 3271: 3268: 3266: 3263: 3261: 3258: 3257: 3256: 3253: 3249: 3246: 3244: 3241: 3239: 3236: 3234: 3231: 3229: 3226: 3225: 3224: 3221: 3220: 3218: 3216: 3212: 3208: 3204: 3201: 3196: 3192: 3176: 3173: 3171: 3168: 3166: 3163: 3161: 3158: 3157: 3156: 3149: 3145: 3142: 3140: 3137: 3135: 3132: 3130: 3127: 3125: 3122: 3120: 3117: 3115: 3112: 3110: 3107: 3105: 3102: 3100: 3097: 3096: 3095: 3088: 3087: 3085: 3083: 3082:Voltage-gated 3079: 3071: 3068: 3066: 3063: 3061: 3058: 3056: 3053: 3052: 3051: 3048: 3047: 3045: 3042: 3038: 3030: 3027: 3025: 3022: 3020: 3017: 3015: 3012: 3011: 3010: 3007: 3006: 3004: 3000: 2996: 2992: 2989: 2984: 2980: 2964: 2961: 2959: 2956: 2955: 2954: 2951: 2947: 2944: 2942: 2939: 2937: 2934: 2932: 2929: 2928: 2927: 2924: 2923: 2918: 2915: 2913: 2910: 2908: 2905: 2903: 2900: 2899: 2898: 2895: 2891: 2888: 2886: 2883: 2881: 2878: 2876: 2873: 2872: 2871: 2868: 2864: 2861: 2859: 2856: 2855: 2854: 2847: 2846: 2841: 2838: 2836: 2833: 2831: 2828: 2827: 2826: 2818: 2815: 2813: 2805: 2802: 2800: 2792: 2789: 2785: 2782: 2781: 2780: 2772: 2769: 2767: 2759: 2756: 2752: 2749: 2747: 2744: 2742: 2739: 2737: 2734: 2733: 2732: 2724: 2721: 2720: 2718: 2716: 2715:Voltage-gated 2712: 2704: 2701: 2699: 2696: 2694: 2691: 2690: 2689: 2686: 2682: 2679: 2677: 2674: 2672: 2669: 2668: 2667: 2664: 2663: 2661: 2657: 2653: 2649: 2646: 2641: 2637: 2632: 2628: 2624: 2617: 2612: 2610: 2605: 2603: 2598: 2597: 2594: 2580: 2574: 2569: 2565: 2559: 2554: 2550: 2544: 2539: 2535: 2529: 2524: 2520: 2514: 2509: 2505: 2496: 2491: 2489: 2484: 2482: 2477: 2476: 2473: 2466: 2462: 2459: 2456: 2452: 2449: 2448: 2444: 2437: 2433: 2428: 2423: 2419: 2415: 2411: 2406: 2402: 2398: 2394: 2390: 2386: 2382: 2379:(1): C290–9. 2378: 2374: 2369: 2365: 2361: 2356: 2351: 2347: 2343: 2339: 2334: 2330: 2326: 2322: 2318: 2313: 2308: 2304: 2300: 2296: 2291: 2287: 2283: 2279: 2275: 2271: 2267: 2262: 2258: 2254: 2250: 2246: 2241: 2236: 2232: 2228: 2227:FASEB Journal 2224: 2219: 2215: 2211: 2206: 2201: 2198:(2): 849–58. 2197: 2193: 2189: 2184: 2180: 2176: 2171: 2166: 2162: 2158: 2155:(1): 109–18. 2154: 2150: 2146: 2141: 2137: 2133: 2129: 2125: 2120: 2115: 2111: 2107: 2103: 2098: 2094: 2090: 2086: 2082: 2078: 2074: 2070: 2066: 2061: 2057: 2053: 2048: 2043: 2039: 2035: 2031: 2026: 2022: 2018: 2013: 2008: 2004: 2000: 1996: 1991: 1987: 1983: 1978: 1973: 1969: 1965: 1961: 1956: 1952: 1948: 1945:(4): 254–60. 1944: 1940: 1935: 1931: 1927: 1923: 1919: 1916:(3): 568–74. 1915: 1911: 1905: 1901: 1897: 1893: 1889: 1885: 1881: 1877: 1873: 1869: 1865: 1860: 1856: 1852: 1847: 1842: 1838: 1834: 1830: 1825: 1821: 1817: 1812: 1807: 1802: 1797: 1793: 1789: 1785: 1781: 1777: 1772: 1768: 1764: 1759: 1754: 1749: 1744: 1740: 1736: 1732: 1728: 1724: 1719: 1718: 1713: 1704: 1700: 1695: 1690: 1686: 1682: 1678: 1674: 1670: 1662: 1659: 1654: 1650: 1645: 1640: 1636: 1632: 1628: 1621: 1618: 1613: 1609: 1605: 1601: 1596: 1591: 1587: 1583: 1579: 1572: 1569: 1564: 1560: 1555: 1550: 1546: 1542: 1538: 1531: 1528: 1523: 1519: 1514: 1509: 1505: 1501: 1498:(1): 109–18. 1497: 1493: 1489: 1482: 1479: 1474: 1470: 1466: 1462: 1458: 1454: 1450: 1446: 1443:(3): 529–37. 1442: 1438: 1431: 1428: 1423: 1419: 1414: 1409: 1406:(2): 849–58. 1405: 1401: 1397: 1390: 1388: 1384: 1379: 1373: 1371: 1367: 1362: 1358: 1354: 1350: 1346: 1342: 1338: 1334: 1326: 1323: 1318: 1314: 1308: 1305: 1300: 1296: 1290: 1287: 1283: 1279: 1274: 1272: 1270: 1266: 1262: 1258: 1253: 1251: 1249: 1245: 1238: 1234: 1231: 1229: 1226: 1225: 1221: 1219: 1217: 1209: 1207: 1205: 1201: 1197: 1193: 1189: 1185: 1181: 1173: 1171: 1164: 1162: 1160: 1157: 1153: 1149: 1141: 1129: 1124: 1120: 1116: 1113: 1109: 1102: 1100: 1097: 1093: 1089: 1085: 1082: 1078: 1074: 1067: 1065: 1059: 1055: 1052: 1046: 1044: 1040: 1034: 1030: 1027: 1023: 1016: 1014: 1008: 1004: 1001: 995: 993: 989: 983: 979: 976: 974:RefSeq (mRNA) 972: 965: 964: 959: 955: 952: 946: 945: 940: 936: 933: 931: 927: 920: 919: 914: 910: 907: 901: 900: 895: 891: 888: 886: 882: 875: 874: 869: 865: 862: 856: 855: 850: 846: 843: 841: 837: 834: 831: 829: 826: 822: 819: 815: 811: 804: 800: 795: 789: 786: 784: 781: 779: 776: 774: 771: 769: 766: 764: 761: 759: 756: 754: 751: 749: 746: 744: 743:ion transport 741: 739: 736: 734: 731: 730: 728: 725: 724: 718: 715: 713: 712:calyx of Held 710: 708: 705: 703: 700: 698: 697:lamellipodium 695: 693: 690: 688: 685: 683: 680: 678: 675: 673: 670: 668: 667:cell junction 665: 663: 660: 658: 655: 653: 650: 648: 645: 643: 640: 638: 635: 633: 630: 628: 625: 623: 620: 618: 615: 613: 610: 608: 607:axon terminus 605: 603: 600: 599: 597: 594: 593: 587: 584: 582: 579: 577: 574: 572: 569: 567: 564: 562: 559: 557: 554: 552: 549: 548: 546: 543: 542: 539: 538:Gene ontology 535: 531: 519: 514: 510: 505: 502: 500: 496: 488: 483: 472: 468: 464: 460: 456: 452: 448: 444: 440: 436: 435: 432: 428: 423: 420: 410: 406: 402: 398: 394: 390: 386: 382: 378: 374: 373: 370: 366: 361: 358: 357: 354: 352: 348: 346: 345: 341: 340: 337: 335: 331: 327: 323: 319: 311: 306: 302: 298: 293: 283: 279: 272: 265: 259: 252: 244: 240: 236: 231: 227: 222: 218: 210: 205: 201: 197: 192: 182: 178: 171: 164: 158: 151: 147: 141: 137: 133: 128: 124: 119: 115: 111: 107: 103: 99: 95: 91: 87: 83: 79: 75: 67: 62: 55: 50: 45: 41: 36: 31: 19: 4863:Ion channels 4835: 4834: 4822: 4789:Ligand-gated 4780: 4768: 4611:Gap junction 4604: 4493: 4289: 4250: 4228: 4201: 4187: 4163: 4141: 4099: 4047: 4013: 3996: 3984: 3965: 3953: 3908: 3871: 3845: 3722: 3593: 3579: 3484: 3431: 3401: 3357: 3286: 3199: 3150: 3089: 2987: 2896: 2869: 2848: 2820: 2807: 2794: 2774: 2761: 2726: 2659:Ligand-gated 2644: 2627:ion channels 2578: 2563: 2548: 2533: 2518: 2417: 2413: 2376: 2372: 2345: 2341: 2302: 2298: 2269: 2265: 2230: 2226: 2195: 2191: 2152: 2148: 2109: 2105: 2068: 2064: 2037: 2033: 2002: 1998: 1967: 1963: 1942: 1938: 1913: 1909: 1867: 1863: 1836: 1832: 1783: 1779: 1730: 1726: 1676: 1672: 1661: 1634: 1630: 1620: 1585: 1581: 1571: 1544: 1540: 1530: 1495: 1491: 1481: 1440: 1437:FEBS Letters 1436: 1430: 1403: 1399: 1336: 1332: 1325: 1316: 1307: 1298: 1289: 1233:Pandinotoxin 1213: 1177: 1174:Interactions 1168: 1155: 1143: 1139: 1138: 1061: 1039:NP_001191198 1036: 1010: 988:NM_001204269 985: 961: 942: 916: 897: 871: 852: 832: 827: 349: 342: 308:107,022,321 295:107,008,462 207:110,631,474 194:110,519,837 69:External IDs 4794:Light-gated 3276:IK channel 2501:PDB gallery 47:Identifiers 4852:Categories 3997:Bestrophin 3255:SK channel 3223:BK channel 2897:γ-subunits 2870:β-subunits 2853:δ-subunits 1284:, May 2017 1263:, May 2017 1239:References 617:perikaryon 353:(ortholog) 90:HomoloGene 4825:disorders 4823:see also 4606:Cytoplasm 4516:Aquaporin 3985:Anoctamin 3808:11.1/hERG 1361:219195192 1204:Cortactin 1064:NP_032443 1043:NP_004965 1013:NM_008417 992:NM_004974 818:Orthologs 98:GeneCards 4619:Connexin 3899:minK/ISK 2436:11739373 2393:11401852 2364:10896669 2329:12444497 2321:10624965 2286:10516156 2257:12876970 2249:10428758 2214:10428084 2136:13943167 2093:23755452 1910:Genomics 1703:27543892 1653:12151401 1612:13943167 1473:40689829 1465:12435606 1422:10428084 1353:16382104 1280:– 1259:– 1222:See also 1210:Clinical 1180:interact 1165:Function 1112:Wikidata 797:Sources: 672:dendrite 632:membrane 4746:Innexin 4503:solutes 2401:2308556 2179:9878055 2170:1171107 2128:9635436 2085:8938729 2056:8889548 2021:8662756 1986:8636142 1951:8002006 1930:7905852 1900:4362906 1892:7477295 1872:Bibcode 1855:2722779 1820:2251283 1788:Bibcode 1767:1715584 1735:Bibcode 1694:5129488 1604:9635436 1563:8636142 1522:9878055 1513:1171107 1445:Bibcode 1282:Ensembl 1261:Ensembl 1152:protein 930:UniProt 885:Ensembl 824:Species 803:QuickGO 647:synapse 328:pattern 54:Aliases 3043:-gated 3041:Proton 2817:T-type 2804:R-type 2791:Q-type 2771:P-type 2758:N-type 2723:L-type 2467:(MeSH) 2457:(MeSH) 2434:  2399:  2391:  2362:  2327:  2319:  2299:Neuron 2284:  2255:  2247:  2212:  2177:  2167:  2134:  2126:  2091:  2083:  2054:  2019:  1984:  1949:  1928:  1898:  1890:  1864:Nature 1853:  1818:  1808:  1765:  1755:  1701:  1691:  1651:  1610:  1602:  1561:  1520:  1510:  1471:  1463:  1420:  1359:  1351:  1196:KCNAB2 1098:search 1096:PubMed 963:P63141 944:P16389 840:Entrez 499:BioGPS 186:1p13.3 78:176262 4657:GJA10 4508:Porin 4408:TRPML 4178:HVCN1 3872:KCNIP 3727:α7-12 2631:TC 1A 2397:S2CID 2325:S2CID 2253:S2CID 2132:S2CID 2089:S2CID 1896:S2CID 1811:55175 1758:52410 1608:S2CID 1469:S2CID 1357:S2CID 1192:PTPRA 1184:KCNA4 1182:with 1156:KCNA2 1150:is a 873:16490 833:Mouse 828:Human 799:Amigo 351:Mouse 344:Human 291:Start 226:Mouse 190:Start 123:Human 102:KCNA2 94:21034 86:96659 61:KCNA2 33:KCNA2 18:Kv1.2 4737:GJD4 4732:GJD3 4727:GJD2 4717:GJC3 4712:GJC2 4707:GJC1 4697:GJB7 4692:GJB6 4687:GJB5 4682:GJB4 4677:GJB3 4672:GJB2 4667:GJB1 4652:GJA9 4647:GJA8 4642:GJA5 4637:GJA4 4632:GJA3 4627:GJA1 4452:TRPV 4435:TRPP 4430:TRPN 4361:TRPM 4314:TRPC 4304:TRPA 4142:CLNS 4100:CLIC 4048:CLCN 4043:CFTR 3990:ANO1 3909:MiRP 3837:12.3 3832:12.2 3827:12.1 3818:11.3 3813:11.2 3799:10.2 3794:10.1 3584:α1-6 3398:GIRK 2812:α2.3 2799:α2.1 2766:α2.2 2579:2a79 2564:1qdw 2549:1qdv 2534:1exb 2519:1dsx 2432:PMID 2389:PMID 2360:PMID 2317:PMID 2282:PMID 2245:PMID 2210:PMID 2175:PMID 2124:PMID 2106:Cell 2081:PMID 2052:PMID 2017:PMID 1982:PMID 1947:PMID 1926:PMID 1888:PMID 1851:PMID 1816:PMID 1763:PMID 1699:PMID 1649:PMID 1600:PMID 1582:Cell 1559:PMID 1518:PMID 1461:PMID 1418:PMID 1349:PMID 1202:and 1200:RHOA 1188:DLG4 1159:gene 854:3737 662:axon 403:pons 334:Bgee 282:Band 243:Chr. 181:Band 140:Chr. 74:OMIM 4501:(+ 4339:4AP 4252:HCN 3785:9.3 3780:9.2 3775:9.1 3766:8.2 3761:8.1 3752:7.5 3747:7.4 3742:7.3 3737:7.2 3732:7.1 3714:6.4 3709:6.3 3704:6.2 3699:6.1 3690:5.1 3681:4.3 3676:4.2 3671:4.1 3662:3.4 3657:3.3 3652:3.2 3647:3.1 3638:2.2 3633:2.1 3624:1.8 3619:1.7 3614:1.6 3609:1.5 3604:1.4 3599:1.3 3594:1.2 3589:1.1 3485:K2P 3465:7.1 3460:6.2 3455:6.1 3450:5.1 3445:4.2 3440:4.1 3425:3.4 3420:3.3 3415:3.2 3410:3.1 3391:2.6 3386:2.4 3381:2.3 3376:2.2 3371:2.1 3366:1.1 3352:ATP 3330:5.1 3325:4.2 3320:4.1 3315:3.1 3310:2.3 3305:2.2 3300:2.1 3295:1.1 3280:IK1 3270:SK3 3265:SK2 3260:SK1 3139:1.9 3134:1.8 3129:1.7 3124:1.6 3119:1.5 3114:1.4 3109:1.3 3104:1.2 3099:1.1 2988:Na: 2840:3.3 2835:3.2 2830:3.1 2784:2.1 2751:1.4 2746:1.3 2741:1.2 2736:1.1 2645:Ca: 2422:doi 2418:277 2381:doi 2377:281 2350:doi 2346:275 2307:doi 2274:doi 2270:277 2235:doi 2200:doi 2165:PMC 2157:doi 2114:doi 2073:doi 2042:doi 2007:doi 2003:271 1972:doi 1968:271 1918:doi 1880:doi 1868:378 1841:doi 1837:264 1806:PMC 1796:doi 1753:PMC 1743:doi 1689:PMC 1681:doi 1639:doi 1635:277 1590:doi 1549:doi 1545:271 1508:PMC 1500:doi 1453:doi 1441:531 1408:doi 1341:doi 1148:1.2 304:End 203:End 106:OMA 82:MGI 4854:: 4723:D 4703:C 4663:B 4623:A 4505:): 4258:FC 4152:1B 4147:1A 4135:L1 4093:KB 4088:KA 3967:Cl 3560:18 3555:17 3550:16 3545:15 3540:13 3535:12 3530:10 3434:ir 3404:ir 3360:ir 3289:Ca 3248:β4 3243:β3 3238:β2 3233:β1 3228:α1 3200:K: 3151:Na 3144:7A 3090:Na 2917:γ4 2912:γ3 2907:γ2 2902:γ1 2890:β4 2885:β3 2880:β2 2875:β1 2821:Ca 2808:Ca 2795:Ca 2775:Ca 2762:Ca 2727:Ca 2625:: 2430:. 2416:. 2412:. 2395:. 2387:. 2375:. 2358:. 2344:. 2340:. 2323:. 2315:. 2303:24 2301:. 2297:. 2280:. 2268:. 2251:. 2243:. 2231:13 2229:. 2225:. 2208:. 2196:73 2194:. 2190:. 2173:. 2163:. 2153:18 2151:. 2147:. 2130:. 2122:. 2110:93 2108:. 2104:. 2087:. 2079:. 2069:35 2067:. 2050:. 2036:. 2032:. 2015:. 2001:. 1997:. 1980:. 1966:. 1962:. 1943:31 1941:. 1924:. 1914:18 1912:. 1894:. 1886:. 1878:. 1866:. 1849:. 1835:. 1831:. 1814:. 1804:. 1794:. 1784:87 1782:. 1778:. 1761:. 1751:. 1741:. 1731:88 1729:. 1725:. 1697:. 1687:. 1677:80 1675:. 1671:. 1647:. 1633:. 1629:. 1606:. 1598:. 1586:93 1584:. 1580:. 1557:. 1543:. 1539:. 1516:. 1506:. 1496:18 1494:. 1490:. 1467:. 1459:. 1451:. 1439:. 1416:. 1404:73 1402:. 1398:. 1386:^ 1369:^ 1355:. 1347:. 1337:57 1335:. 1315:. 1297:. 1268:^ 1247:^ 1218:. 1206:. 1198:, 1194:, 1190:, 1186:, 1161:. 801:/ 310:bp 297:bp 209:bp 196:bp 104:; 100:: 96:; 92:: 88:; 84:: 80:; 76:: 4844:. 4608:: 4588:3 4583:2 4578:1 4566:9 4561:8 4556:7 4551:6 4546:5 4541:4 4536:3 4531:2 4526:1 4521:0 4499:O 4497:2 4495:H 4482:6 4477:5 4472:4 4467:3 4462:2 4457:1 4445:2 4440:1 4423:3 4418:2 4413:1 4401:8 4396:7 4391:6 4386:5 4381:4 4376:3 4371:2 4366:1 4354:7 4349:6 4344:5 4334:4 4329:3 4324:2 4319:1 4310:) 4308:1 4306:( 4293:: 4291:M 4278:4 4273:3 4268:2 4263:1 4244:3 4239:2 4234:1 4229:β 4222:4 4217:3 4212:2 4207:1 4202:α 4191:: 4189:M 4167:: 4165:H 4130:6 4125:5 4120:4 4115:3 4110:2 4105:1 4083:7 4078:6 4073:5 4068:4 4063:3 4058:2 4053:1 4034:4 4029:3 4024:2 4019:1 4007:2 4002:1 3969:: 3924:3 3919:2 3914:1 3892:4 3887:3 3882:2 3877:1 3865:3 3860:2 3855:1 3850:β 3848:v 3846:K 3725:v 3723:K 3582:v 3580:K 3525:9 3520:7 3515:6 3510:5 3505:4 3500:3 3495:2 3490:1 3432:K 3402:K 3400:/ 3358:K 3350:K 3287:K 3175:4 3170:3 3165:2 3160:1 3155:β 3153:v 3094:α 3092:v 3070:4 3065:3 3060:2 3055:1 3029:δ 3024:γ 3019:β 3014:α 2963:2 2958:1 2946:4 2941:3 2936:2 2931:1 2863:2 2858:1 2851:2 2849:α 2825:α 2823:v 2819:/ 2810:v 2806:/ 2797:v 2793:/ 2779:α 2777:v 2773:/ 2764:v 2760:/ 2731:α 2729:v 2725:/ 2703:3 2698:2 2693:1 2681:3 2676:2 2671:1 2633:) 2629:( 2615:e 2608:t 2601:v 2494:e 2487:t 2480:v 2438:. 2424:: 2403:. 2383:: 2366:. 2352:: 2331:. 2309:: 2288:. 2276:: 2259:. 2237:: 2216:. 2202:: 2181:. 2159:: 2138:. 2116:: 2095:. 2075:: 2058:. 2044:: 2038:6 2023:. 2009:: 1988:. 1974:: 1953:. 1932:. 1920:: 1902:. 1882:: 1874:: 1857:. 1843:: 1822:. 1798:: 1790:: 1769:. 1745:: 1737:: 1705:. 1683:: 1655:. 1641:: 1614:. 1592:: 1565:. 1551:: 1524:. 1502:: 1475:. 1455:: 1447:: 1424:. 1410:: 1380:. 1363:. 1343:: 1319:. 1301:. 1146:v 1144:K 228:) 125:) 108:: 20:)

Index

Kv1.2

Aliases
KCNA2
OMIM
176262
MGI
96659
HomoloGene
21034
GeneCards
KCNA2
OMA
KCNA2 - orthologs
Human
Chromosome 1 (human)
Chr.
Chromosome 1 (human)
Chromosome 1 (human)
Genomic location for KCNA2
Genomic location for KCNA2
Band
bp
bp
Mouse
Chromosome 3 (mouse)
Chr.
Chromosome 3 (mouse)
Genomic location for KCNA2
Genomic location for KCNA2

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.