297:
274:
171:
196:
303:
202:
1663:
1098:
is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of
50:
310:
209:
797:
778:
132:
1456:
McNally KP, Bazirgan OA, McNally FJ (2000). "Two domains of p80 katanin regulate microtubule severing and spindle pole targeting by p60 katanin".
1732:
1708:
1180:
1162:
1727:
296:
1003:
273:
1010:
1250:
1337:"Katanin, a microtubule-severing protein, is a novel AAA ATPase that targets to the centrosome using a WD40-containing subunit"
1149:
1128:
1306:
McNally FJ, Okawa K, Iwamatsu A, Vale RD (1997). "Katanin, the microtubule-severing ATPase, is concentrated at centrosomes".
1145:
195:
170:
47:
1124:
112:
1485:
Buster D, McNally K, McNally FJ (2002). "Katanin inhibition prevents the redistribution of gamma-tubulin at mitosis".
309:
208:
1269:
McNally FJ, Vale RD (1993). "Identification of katanin, an ATPase that severs and disassembles stable microtubules".
302:
201:
1701:
842:
120:
1612:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
823:
1694:
1580:
1527:
184:
99:
963:
912:
1366:
1294:
144:
1516:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
967:
937:
916:
1641:
1598:
1555:
1502:
1473:
1444:
1409:
1358:
1323:
1286:
1229:
92:
40:
1678:
1631:
1623:
1588:
1545:
1535:
1494:
1465:
1434:
1399:
1391:
1348:
1315:
1278:
1219:
1211:
389:
320:
264:
219:
140:
1087:
364:
1584:
1531:
1404:
1379:
1636:
1611:
1550:
1515:
1439:
1422:
1353:
1336:
1200:"Katanin is responsible for the M-phase microtubule-severing activity in Xenopus eggs"
712:
707:
702:
697:
681:
676:
671:
666:
661:
656:
651:
646:
641:
636:
620:
615:
610:
605:
600:
595:
590:
585:
580:
1721:
1282:
1224:
1199:
567:
1370:
1298:
124:
1674:
1100:
382:
161:
148:
1185:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1167:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1079:
465:
1091:
281:
178:
128:
742:
525:
403:
348:
335:
247:
234:
136:
1645:
1602:
1559:
1540:
1506:
1498:
1477:
1469:
1448:
1413:
1395:
1362:
1327:
1319:
1290:
1233:
1050:
1045:
1215:
1034:
887:
868:
1593:
1568:
1627:
1095:
1083:
854:
809:
1380:"An essential role for katanin in severing microtubules in the neuron"
69:
1090:
of a dividing cell and help to organize membranous organelles during
1066:
1018:
764:
1662:
1423:"Lipotransin: a novel docking protein for hormone-sensitive lipase"
1251:"Entrez Gene: KATNA1 katanin p60 (ATPase-containing) subunit A 1"
727:
723:
1670:
1073:
116:
1514:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
372:
1682:
1610:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1569:"The DNA sequence and analysis of human chromosome 6"
537:
1567:
Mungall AJ, Palmer SA, Sims SK, et al. (2003).
1335:Hartman JJ, Mahr J, McNally K, et al. (1998).
981:
956:
930:
905:
1141:
1139:
1137:
1120:
1118:
1116:
319:
218:
16:Protein-coding gene in the species Homo sapiens
1146:GRCm38: Ensembl release 89: ENSMUSG00000019794
1702:
8:
1378:Ahmad FJ, Yu W, McNally FJ, Baas PW (1999).
1125:GRCh38: Ensembl release 89: ENSG00000186625
1709:
1695:
738:
563:
360:
259:
156:
58:
1635:
1592:
1549:
1539:
1438:
1403:
1352:
1223:
1245:
1243:
1063:Katanin p60 ATPase-containing subunit A1
1112:
18:
324:
285:
280:
223:
182:
177:
7:
1659:
1657:
713:cytoplasmic microtubule organization
591:microtubule-severing ATPase activity
601:protein heterodimerization activity
1681:. You can help Knowledge (XXG) by
978:
953:
927:
902:
878:
859:
833:
814:
788:
769:
542:
460:
398:
377:
14:
1198:McNally FJ, Thomas S (Jan 1999).
1069:that in humans is encoded by the
1661:
308:
301:
295:
272:
207:
200:
194:
169:
526:More reference expression data
103:, katanin catalytic subunit A1
1:
1733:Human chromosome 6 gene stubs
1440:10.1016/S1097-2765(00)80192-6
1354:10.1016/S0092-8674(00)81578-0
1082:, polymers of alpha and beta
667:microtubule organizing center
293:
192:
1520:Proc. Natl. Acad. Sci. U.S.A
1283:10.1016/0092-8674(93)90377-3
1728:Genes on human chromosome 6
1421:Syu LJ, Saltiel AR (1999).
1749:
1656:
438:retinal pigment epithelium
1181:"Mouse PubMed Reference:"
1163:"Human PubMed Reference:"
1049:
1044:
1040:
1033:
1017:
1004:Chr 6: 149.59 – 149.65 Mb
998:
985:
960:
949:
934:
909:
898:
885:
881:
866:
862:
853:
840:
836:
821:
817:
808:
795:
791:
776:
772:
763:
748:
741:
737:
721:
566:
562:
550:
545:
536:
523:
472:
463:
450:Descending thoracic aorta
410:
401:
371:
363:
359:
342:
329:
292:
271:
262:
258:
241:
228:
191:
168:
159:
155:
110:
107:
97:
90:
85:
66:
61:
44:
39:
34:
30:
26:
21:
1541:10.1073/pnas.242603899
1499:10.1242/jcs.115.5.1083
1470:10.1242/jcs.113.9.1623
1396:10.1083/jcb.145.2.305
1320:10.1242/jcs.109.3.561
1101:AAA family of ATPases
1011:Chr 10: 7.6 – 7.64 Mb
287:Chromosome 10 (mouse)
1216:10.1091/mbc.9.7.1847
703:microtubule severing
677:mitotic spindle pole
446:gastrocnemius muscle
185:Chromosome 6 (human)
62:List of PDB id codes
35:Available structures
1594:10.1038/nature02055
1585:2003Natur.425..805M
1532:2002PNAS...9916899M
1086:subunits, form the
586:microtubule binding
1669:This article on a
1628:10.1101/gr.2596504
843:ENSMUSG00000019794
691:Biological process
630:Cellular component
621:isomerase activity
606:hydrolase activity
581:nucleotide binding
574:Molecular function
149:KATNA1 - orthologs
1690:
1689:
1526:(26): 16899–903.
1493:(Pt 5): 1083–92.
1060:
1059:
1056:
1055:
1029:
1028:
994:
993:
975:
974:
945:
944:
924:
923:
894:
893:
875:
874:
849:
848:
830:
829:
804:
803:
785:
784:
733:
732:
558:
557:
554:
553:
532:
531:
519:
518:
457:
456:
355:
354:
254:
253:
81:
80:
77:
76:
45:Ortholog search:
1740:
1711:
1704:
1697:
1665:
1658:
1649:
1639:
1606:
1596:
1579:(6960): 805–11.
1563:
1553:
1543:
1510:
1481:
1452:
1442:
1417:
1407:
1374:
1356:
1331:
1302:
1255:
1254:
1247:
1238:
1237:
1227:
1195:
1189:
1188:
1177:
1171:
1170:
1159:
1153:
1143:
1132:
1122:
1042:
1041:
1013:
1006:
989:
979:
970:
954:
950:RefSeq (protein)
940:
928:
919:
903:
879:
860:
834:
815:
789:
770:
739:
564:
543:
528:
508:secondary oocyte
468:
466:Top expressed in
461:
418:secondary oocyte
406:
404:Top expressed in
399:
378:
361:
351:
338:
327:
312:
305:
299:
288:
276:
260:
250:
237:
226:
211:
204:
198:
187:
173:
157:
151:
102:
95:
72:
59:
53:
32:
31:
19:
1748:
1747:
1743:
1742:
1741:
1739:
1738:
1737:
1718:
1717:
1716:
1715:
1654:
1652:
1622:(10B): 2121–7.
1609:
1566:
1513:
1484:
1455:
1420:
1377:
1334:
1305:
1268:
1264:
1262:Further reading
1259:
1258:
1249:
1248:
1241:
1197:
1196:
1192:
1179:
1178:
1174:
1161:
1160:
1156:
1144:
1135:
1123:
1114:
1109:
1088:mitotic spindle
1051:View/Edit Mouse
1046:View/Edit Human
1009:
1002:
999:Location (UCSC)
987:
966:
962:
936:
915:
911:
824:ENSG00000186625
717:
686:
625:
616:ATPase activity
596:protein binding
524:
515:
510:
506:
502:
498:
494:
490:
486:
482:
478:
464:
453:
448:
444:
440:
436:
434:Achilles tendon
432:
428:
424:
420:
416:
402:
346:
333:
325:
315:
314:
313:
306:
286:
263:Gene location (
245:
232:
224:
214:
213:
212:
205:
183:
160:Gene location (
111:
98:
91:
68:
46:
17:
12:
11:
5:
1746:
1744:
1736:
1735:
1730:
1720:
1719:
1714:
1713:
1706:
1699:
1691:
1688:
1687:
1666:
1651:
1650:
1607:
1564:
1511:
1482:
1464:(9): 1623–33.
1453:
1418:
1375:
1332:
1303:
1265:
1263:
1260:
1257:
1256:
1239:
1210:(7): 1847–61.
1190:
1172:
1154:
1133:
1111:
1110:
1108:
1105:
1058:
1057:
1054:
1053:
1048:
1038:
1037:
1031:
1030:
1027:
1026:
1024:
1022:
1015:
1014:
1007:
1000:
996:
995:
992:
991:
983:
982:
976:
973:
972:
958:
957:
951:
947:
946:
943:
942:
932:
931:
925:
922:
921:
907:
906:
900:
896:
895:
892:
891:
883:
882:
876:
873:
872:
864:
863:
857:
851:
850:
847:
846:
838:
837:
831:
828:
827:
819:
818:
812:
806:
805:
802:
801:
793:
792:
786:
783:
782:
774:
773:
767:
761:
760:
755:
750:
746:
745:
735:
734:
731:
730:
719:
718:
716:
715:
710:
705:
700:
694:
692:
688:
687:
685:
684:
679:
674:
669:
664:
659:
654:
649:
644:
639:
633:
631:
627:
626:
624:
623:
618:
613:
608:
603:
598:
593:
588:
583:
577:
575:
571:
570:
560:
559:
556:
555:
552:
551:
548:
547:
540:
534:
533:
530:
529:
521:
520:
517:
516:
514:
513:
509:
505:
501:
500:primary oocyte
497:
493:
489:
485:
481:
477:
473:
470:
469:
458:
455:
454:
452:
451:
447:
443:
439:
435:
431:
427:
423:
419:
415:
411:
408:
407:
395:
394:
386:
375:
369:
368:
365:RNA expression
357:
356:
353:
352:
344:
340:
339:
331:
328:
323:
317:
316:
307:
300:
294:
290:
289:
284:
278:
277:
269:
268:
256:
255:
252:
251:
243:
239:
238:
230:
227:
222:
216:
215:
206:
199:
193:
189:
188:
181:
175:
174:
166:
165:
153:
152:
109:
105:
104:
96:
88:
87:
83:
82:
79:
78:
75:
74:
64:
63:
55:
54:
43:
37:
36:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1745:
1734:
1731:
1729:
1726:
1725:
1723:
1712:
1707:
1705:
1700:
1698:
1693:
1692:
1686:
1684:
1680:
1676:
1672:
1667:
1664:
1660:
1655:
1647:
1643:
1638:
1633:
1629:
1625:
1621:
1617:
1613:
1608:
1604:
1600:
1595:
1590:
1586:
1582:
1578:
1574:
1570:
1565:
1561:
1557:
1552:
1547:
1542:
1537:
1533:
1529:
1525:
1521:
1517:
1512:
1508:
1504:
1500:
1496:
1492:
1488:
1483:
1479:
1475:
1471:
1467:
1463:
1459:
1454:
1450:
1446:
1441:
1436:
1433:(1): 109–15.
1432:
1428:
1424:
1419:
1415:
1411:
1406:
1401:
1397:
1393:
1390:(2): 305–15.
1389:
1385:
1381:
1376:
1372:
1368:
1364:
1360:
1355:
1350:
1347:(2): 277–87.
1346:
1342:
1338:
1333:
1329:
1325:
1321:
1317:
1313:
1309:
1304:
1300:
1296:
1292:
1288:
1284:
1280:
1277:(3): 419–29.
1276:
1272:
1267:
1266:
1261:
1252:
1246:
1244:
1240:
1235:
1231:
1226:
1221:
1217:
1213:
1209:
1205:
1204:Mol Biol Cell
1201:
1194:
1191:
1186:
1182:
1176:
1173:
1168:
1164:
1158:
1155:
1151:
1147:
1142:
1140:
1138:
1134:
1130:
1126:
1121:
1119:
1117:
1113:
1106:
1104:
1102:
1097:
1093:
1089:
1085:
1081:
1077:
1075:
1072:
1068:
1064:
1052:
1047:
1043:
1039:
1036:
1032:
1025:
1023:
1020:
1016:
1012:
1008:
1005:
1001:
997:
990:
984:
980:
977:
971:
969:
965:
959:
955:
952:
948:
941:
939:
933:
929:
926:
920:
918:
914:
908:
904:
901:
899:RefSeq (mRNA)
897:
890:
889:
884:
880:
877:
871:
870:
865:
861:
858:
856:
852:
845:
844:
839:
835:
832:
826:
825:
820:
816:
813:
811:
807:
800:
799:
794:
790:
787:
781:
780:
775:
771:
768:
766:
762:
759:
756:
754:
751:
747:
744:
740:
736:
729:
725:
720:
714:
711:
709:
706:
704:
701:
699:
698:cell division
696:
695:
693:
690:
689:
683:
680:
678:
675:
673:
670:
668:
665:
663:
660:
658:
655:
653:
650:
648:
645:
643:
640:
638:
635:
634:
632:
629:
628:
622:
619:
617:
614:
612:
609:
607:
604:
602:
599:
597:
594:
592:
589:
587:
584:
582:
579:
578:
576:
573:
572:
569:
568:Gene ontology
565:
561:
549:
544:
541:
539:
535:
527:
522:
511:
507:
503:
499:
495:
491:
487:
483:
479:
475:
474:
471:
467:
462:
459:
449:
445:
441:
437:
433:
429:
425:
421:
417:
413:
412:
409:
405:
400:
397:
396:
393:
391:
387:
385:
384:
380:
379:
376:
374:
370:
366:
362:
358:
350:
345:
341:
337:
332:
326:10|10 A1
322:
318:
311:
304:
298:
291:
283:
279:
275:
270:
266:
261:
257:
249:
244:
240:
236:
231:
221:
217:
210:
203:
197:
190:
186:
180:
176:
172:
167:
163:
158:
154:
150:
146:
142:
138:
134:
130:
126:
122:
118:
114:
106:
101:
94:
89:
84:
73:
71:
65:
60:
57:
56:
52:
49:
42:
38:
33:
29:
25:
20:
1683:expanding it
1675:chromosome 6
1668:
1653:
1619:
1615:
1576:
1572:
1523:
1519:
1490:
1486:
1461:
1457:
1430:
1426:
1387:
1384:J. Cell Biol
1383:
1344:
1340:
1314:(3): 561–7.
1311:
1307:
1274:
1270:
1207:
1203:
1193:
1184:
1175:
1166:
1157:
1080:Microtubules
1078:
1070:
1062:
1061:
986:
964:NP_001191005
961:
935:
913:NM_001204076
910:
886:
867:
841:
822:
796:
777:
757:
752:
657:cytoskeleton
642:spindle pole
492:zone of skin
430:right testis
388:
381:
246:149,648,972
233:149,594,873
108:External IDs
67:
1487:J. Cell Sci
1458:J. Cell Sci
1308:J. Cell Sci
652:microtubule
611:ATP binding
484:bone marrow
476:granulocyte
426:left testis
86:Identifiers
1722:Categories
1616:Genome Res
1152:, May 2017
1131:, May 2017
1107:References
1092:interphase
708:cell cycle
682:centrosome
392:(ortholog)
347:7,638,914
334:7,601,764
129:HomoloGene
1673:on human
1427:Mol. Cell
968:NP_008975
938:NM_011835
917:NM_007044
743:Orthologs
637:cytoplasm
512:esophagus
137:GeneCards
1646:15489334
1603:14574404
1560:12477932
1507:11870226
1478:10751153
1449:10445032
1414:10209026
1371:13583382
1299:10264319
1148:–
1127:–
1035:Wikidata
722:Sources:
480:epiblast
442:testicle
1581:Bibcode
1528:Bibcode
1405:2133110
1363:9568719
1328:8907702
1291:8221885
1234:9658175
1150:Ensembl
1129:Ensembl
1096:Katanin
1084:tubulin
855:UniProt
810:Ensembl
749:Species
728:QuickGO
672:spindle
662:nucleus
647:midbody
367:pattern
125:1344353
93:Aliases
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1071:KATNA1
1067:enzyme
1065:is an
1021:search
1019:PubMed
888:Q9WV86
869:O75449
765:Entrez
538:BioGPS
504:thymus
488:zygote
225:6q25.1
141:KATNA1
117:606696
100:KATNA1
22:KATNA1
1677:is a
1367:S2CID
1295:S2CID
1225:25426
798:23924
779:11104
758:Mouse
753:Human
724:Amigo
496:ileum
422:gonad
414:sperm
390:Mouse
383:Human
330:Start
265:Mouse
229:Start
162:Human
133:56014
1679:stub
1671:gene
1642:PMID
1599:PMID
1556:PMID
1503:PMID
1474:PMID
1445:PMID
1410:PMID
1359:PMID
1341:Cell
1324:PMID
1287:PMID
1271:Cell
1230:PMID
1099:the
1074:gene
373:Bgee
321:Band
282:Chr.
220:Band
179:Chr.
113:OMIM
70:2RPA
51:RCSB
48:PDBe
1632:PMC
1624:doi
1589:doi
1577:425
1546:PMC
1536:doi
1495:doi
1491:115
1466:doi
1462:113
1435:doi
1400:PMC
1392:doi
1388:145
1349:doi
1316:doi
1312:109
1279:doi
1220:PMC
1212:doi
988:n/a
546:n/a
343:End
242:End
145:OMA
121:MGI
41:PDB
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