1259:
transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
297:
274:
171:
196:
4871:
548:
303:
202:
1258:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte
50:
1490:
Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, et al. (December 2005). "International Union of
Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels".
2240:
Ziechner U, Schönherr R, Born AK, Gavrilova-Ruch O, Glaser RW, Malesevic M, et al. (March 2006). "Inhibition of human ether à go-go potassium channels by Ca2+/calmodulin binding to the cytosolic N- and C-termini".
1327:, resulting in the multisystem developmental disorder. TBS is categorized by intellectual disabilities, epilepsy, typical facial features, and aplasia of the nails. Simons et al. demonstrated that mutational
2500:
Simons C, Rash LD, Crawford J, Ma L, Cristofori-Armstrong B, Miller D, et al. (January 2015). "Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy".
1671:
Simons C, Rash LD, Crawford J, Ma L, Cristofori-Armstrong B, Miller D, et al. (January 2015). "Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy".
1331:
present in the mothers of some probands was responsible for their children's TBS phenotype. This is further evidence of the role that genetic mosaicism plays in the etiology of neurological disorders.
2203:
Kang J, Chen XL, Wang H, Ji J, Cheng H, Incardona J, et al. (March 2005). "Discovery of a small molecule activator of the human ether-a-go-go-related gene (HERG) cardiac K+ channel".
3427:
1819:
Bramswig NC, Ockeloen CW, Czeschik JC, van Essen AJ, Pfundt R, Smeitink J, et al. (October 2015). "'Splitting versus lumping': Temple-Baraitser and
Zimmermann-Laband Syndromes".
4337:
4072:
3324:
3257:
310:
209:
1628:
Gabbett MT, Clark RC, McGaughran JM (February 2008). "A second case of severe mental retardation and absent nails of hallux and pollex (Temple-Baraitser syndrome)".
4912:
2166:
Farias LM, Ocaña DB, Díaz L, Larrea F, Avila-Chávez E, Cadena A, et al. (October 2004). "Ether a go-go potassium channels as human cervical cancer markers".
1342:. This has led some researchers to believe that type 1 Zimmermann-Laband and Temple-Baraitser syndromes are different manifestations of the same disorder.
2611:
1715:
Kortüm F, Caputo V, Bauer CK, Stella L, Ciolfi A, Alawi M, et al. (June 2015). "Mutations in KCNH1 and ATP6V1B2 cause
Zimmermann-Laband syndrome".
966:
132:
1922:"KCR1, a membrane protein that facilitates functional expression of non-inactivating K+ currents associates with rat EAG voltage-dependent K+ channels"
947:
4936:
4268:
4251:
4246:
4241:
4236:
4273:
3371:
2643:
1431:
1413:
4931:
4325:
3506:
4905:
4223:
3244:
2660:
2591:
1182:
296:
4009:
1189:
273:
2458:"IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation"
2457:
1537:
2076:
Schönherr R, Gessner G, Löber K, Heinemann SH (March 2002). "Functional distinction of human EAG1 and EAG2 potassium channels".
4941:
4602:
3601:
3379:
2695:
2115:"Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome"
1553:"Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome"
1400:
1379:
1351:
1324:
1291:
1335:
4898:
4624:
1396:
1306:
195:
170:
47:
4833:
2744:
1375:
4199:
3111:
112:
4474:
1268:
309:
208:
2652:
2636:
302:
201:
4828:
3038:
4818:
3079:
2955:
2559:
2549:
1011:
120:
1302:
2280:"Silencing the activity and proliferative properties of the human EagI Potassium Channel by RNA Interference"
4823:
992:
4854:
2846:
2833:
2820:
2800:
2787:
2752:
2360:"KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging"
103:, EAG, EAG1, Kv10.1, h-eag, TMBTS, ZLS1, hEAG1, potassium voltage-gated channel subfamily H member 1, hEAG
2629:
1449:
Occhiodoro T, Bernheim L, Liu JH, Bijlenga P, Sinnreich M, Bader CR, Fischer-Lougheed J (August 1998).
2727:
2413:"Aberrant expression of ether à go-go potassium channel in colorectal cancer patients and cell lines"
2371:
2126:
1880:
1564:
184:
2555:
99:
2621:
1161:
1106:
2545:
1451:"Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion"
4194:
3070:
2717:
2526:
2488:
2456:
Borowiec AS, Hague F, Harir N, Guénin S, Guerineau F, Gouilleux F, et al. (September 2007).
2266:
2228:
2191:
2101:
1844:
1750:
1697:
1653:
1516:
144:
1165:
1140:
1136:
1110:
1085:
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3232:
2518:
2480:
2444:
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2301:
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2220:
2183:
2154:
2093:
2064:
2029:
1986:
1943:
1908:
1836:
1801:
1742:
1689:
1645:
1592:
1508:
1472:
1328:
547:
92:
40:
4882:
1955:
Pardo LA, del Camino D, Sánchez A, Alves F, Brüggemann A, Beckh S, Stühmer W (October 1999).
4878:
4870:
4001:
2982:
2510:
2472:
2434:
2424:
2389:
2379:
2336:
2326:
2291:
2250:
2212:
2175:
2144:
2134:
2085:
2054:
2019:
2011:
1976:
1968:
1933:
1898:
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1828:
1791:
1781:
1732:
1724:
1681:
1637:
1582:
1572:
1500:
1462:
1315:
1310:
389:
320:
264:
219:
140:
4537:
2677:
364:
1538:"Entrez Gene: KCNH1 potassium voltage-gated channel, subfamily H (eag-related), member 1"
2375:
2130:
1884:
1568:
4333:
3020:
2439:
2412:
2394:
2359:
2358:
Ocorr K, Reeves NL, Wessells RJ, Fink M, Chen HS, Akasaka T, et al. (March 2007).
2341:
2314:
1981:
1956:
1796:
1769:
2149:
2114:
2089:
2024:
1999:
1768:
Mégarbané A, Al-Ali R, Choucair N, Lek M, Wang E, Ladjimi M, et al. (June 2016).
1587:
1552:
1467:
1450:
881:
876:
871:
866:
861:
856:
851:
846:
841:
836:
831:
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619:
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589:
4925:
4287:
3960:
2615:
2254:
1903:
1868:
1520:
576:
2530:
2492:
2270:
2232:
1848:
1754:
1701:
124:
4640:
4031:
2195:
2105:
1657:
382:
161:
2179:
148:
4570:
4565:
4560:
4555:
4442:
4281:
2656:
1770:"Temple-Baraitser Syndrome and Zimmermann-Laband Syndrome: one clinical entity?"
1436:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1418:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1313:
Profs Karen Temple and
Michael Baraitser. They then went on to demonstrate that
2364:
Proceedings of the
National Academy of Sciences of the United States of America
2119:
Proceedings of the
National Academy of Sciences of the United States of America
2015:
1972:
1920:
Hoshi N, Takahashi H, Shahidullah M, Yokoyama S, Higashida H (September 1998).
1873:
Proceedings of the
National Academy of Sciences of the United States of America
1557:
Proceedings of the
National Academy of Sciences of the United States of America
465:
4550:
3916:
3284:
3252:
1869:"A family of potassium channel genes related to eag in Drosophila and mammals"
1832:
1786:
281:
178:
128:
2278:
Weber C, de Queiroz FM, Downie BR, Suckow A, Stühmer W, Pardo LA (May 2006).
1938:
1921:
4635:
4545:
2429:
2384:
2315:"Ether à go-go potassium channel expression in soft tissue sarcoma patients"
911:
525:
403:
348:
335:
247:
234:
136:
2522:
2484:
2448:
2403:
2350:
2331:
2305:
2296:
2279:
2262:
2224:
2216:
2187:
2158:
2139:
2097:
2068:
2059:
2042:
2033:
2000:"Inhibition of human ether à go-go potassium channels by Ca(2+)/calmodulin"
1990:
1893:
1840:
1805:
1746:
1693:
1649:
1596:
1577:
1512:
2583:
1947:
1912:
1476:
1229:
1224:
4648:
3996:
2975:
2970:
2965:
2960:
2892:
2887:
1641:
1611:"603305 - Potassium channel, voltage-gated; subfamily H, member 1; KCNH1"
1213:
1056:
1037:
2313:
Mello de Queiroz F, Suarez-Kurtz G, Stühmer W, Pardo LA (October 2006).
4775:
4532:
4368:
2869:
2864:
2859:
1737:
1504:
1245:
1023:
978:
2476:
69:
4452:
4447:
4181:
4176:
4122:
4117:
3933:
3921:
3911:
3906:
3894:
3889:
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3584:
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3489:
3479:
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3420:
3415:
3405:
3400:
3277:
3272:
3267:
3262:
3168:
3163:
3158:
3148:
3143:
3133:
3128:
3058:
3053:
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2936:
2931:
2919:
2914:
2909:
2904:
2813:
2780:
2775:
2770:
2765:
2565:
1197:
933:
2514:
1728:
1685:
1610:
4686:
4617:
4612:
4607:
4524:
4511:
4506:
4501:
4496:
4491:
4486:
4437:
4430:
4425:
4420:
4415:
4410:
4405:
4400:
4395:
4383:
4378:
4373:
4363:
4358:
4353:
4348:
4263:
4207:
4164:
4159:
4154:
4149:
4144:
4139:
4134:
4112:
4107:
4102:
4097:
4092:
4087:
4082:
4063:
4058:
4053:
4048:
4036:
3953:
3948:
3943:
3928:
3866:
3861:
3856:
3847:
3842:
3828:
3814:
3809:
3804:
3795:
3790:
3781:
3776:
3743:
3738:
3733:
3728:
3719:
3710:
3705:
3700:
3691:
3686:
3681:
3676:
3667:
3662:
3648:
3643:
3638:
3633:
3628:
3623:
3618:
3554:
3549:
3544:
3539:
3534:
3529:
3524:
3519:
3484:
3454:
3449:
3444:
3439:
3410:
3359:
3354:
3349:
3344:
3334:
3329:
3309:
3294:
3289:
3204:
3199:
3194:
3189:
3173:
3153:
3138:
3099:
3094:
3089:
3084:
2992:
2987:
2710:
2705:
2700:
1272:
1294:
with predominant expression in the adult central nervous system.
896:
892:
4766:
4761:
4756:
4746:
4741:
4736:
4726:
4721:
4716:
4711:
4706:
4701:
4696:
4681:
4676:
4671:
4666:
4661:
4656:
4595:
4590:
4585:
4580:
4575:
4481:
4469:
4464:
4459:
4390:
4343:
4307:
4302:
4297:
4292:
4019:
3837:
3395:
2732:
2722:
2596:
1287:
1252:
116:
4796:
3981:
3227:
3015:
2672:
2625:
556:
4320:
4218:
3339:
3299:
2113:
Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ (June 2002).
1551:
Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ (June 2002).
2043:"Regulation of an ERG K+ current by Src tyrosine kinase"
372:
4886:
2411:
Ding XW, Yan JJ, An P, Lü P, Luo HS (February 2007).
1338:
was later found to be caused by similar mutations in
537:
2573:
1242:
Potassium voltage-gated channel subfamily H member 1
4809:
4633:
4522:
4318:
4216:
4192:
3994:
3600:
3505:
3370:
3243:
3110:
3069:
3031:
2743:
2688:
2577:
1154:
1129:
1099:
1074:
1392:
1390:
1388:
1371:
1369:
1367:
1309:(TBS) in 2008, naming the condition after English
319:
218:
1998:Schönherr R, Löber K, Heinemann SH (July 2000).
1323:gene cause deleterious gain of function in the
16:Protein-coding gene in the species Homo sapiens
1397:GRCm38: Ensembl release 89: ENSMUSG00000058248
4906:
2637:
8:
1630:American Journal of Medical Genetics. Part A
640:delayed rectifier potassium channel activity
1376:GRCh38: Ensembl release 89: ENSG00000143473
822:regulation of cell population proliferation
4913:
4899:
4806:
4793:
3991:
3978:
3240:
3224:
3028:
3012:
2685:
2669:
2644:
2630:
2622:
2612:United States National Library of Medicine
2574:
1957:"Oncogenic potential of EAG K(+) channels"
1615:Online Mendelian Inheritance in Man (OMIM)
907:
801:integral component of presynaptic membrane
572:
360:
259:
156:
58:
2558:at the U.S. National Library of Medicine
2548:at the U.S. National Library of Medicine
2438:
2428:
2393:
2383:
2340:
2330:
2295:
2148:
2138:
2058:
2041:Cayabyab FS, Schlichter LC (April 2002).
2023:
1980:
1937:
1902:
1892:
1795:
1785:
1736:
1586:
1576:
1466:
842:regulation of ion transmembrane transport
635:phosphatidylinositol bisphosphate binding
2610:This article incorporates text from the
1532:
1530:
761:intracellular membrane-bounded organelle
595:voltage-gated potassium channel activity
1363:
867:phosphatidylinositol-mediated signaling
837:phosphorelay signal transduction system
736:voltage-gated potassium channel complex
18:
852:potassium ion transmembrane transport
771:integral component of plasma membrane
324:
285:
280:
223:
182:
177:
7:
4867:
4865:
1867:Warmke JW, Ganetzky B (April 1994).
4010:Calcium-activated chloride channels
2284:The Journal of Biological Chemistry
2047:The Journal of Biological Chemistry
1926:The Journal of Biological Chemistry
660:protein heterodimerization activity
590:phosphorelay sensor kinase activity
4885:. You can help Knowledge (XXG) by
3080:Amiloride-sensitive cation channel
1151:
1126:
1096:
1071:
1047:
1028:
1002:
983:
957:
938:
620:voltage-gated ion channel activity
542:
460:
398:
377:
14:
2417:World Journal of Gastroenterology
1248:that in humans is encoded by the
655:transmembrane transporter binding
4869:
2255:10.1111/j.1742-4658.2006.05134.x
882:cellular response to calcium ion
862:regulation of membrane potential
546:
308:
301:
295:
272:
207:
200:
194:
169:
4603:Voltage-dependent anion channel
2696:Inositol trisphosphate receptor
1352:Voltage-gated potassium channel
1325:voltage-gated potassium channel
1292:voltage-gated potassium channel
796:perinuclear region of cytoplasm
4937:PAS-domain-containing proteins
4625:General bacterial porin family
2465:Journal of Cellular Physiology
686:integral component of membrane
557:More reference expression data
526:More reference expression data
434:right hemisphere of cerebellum
1:
2180:10.1158/0008-5472.CAN-04-1204
2090:10.1016/S0014-5793(02)02365-7
1468:10.1016/S0014-5793(98)00973-9
293:
192:
4932:Genes on human chromosome 1
1290:encodes a highly conserved
877:ion transmembrane transport
4958:
4864:
4044:Chloride Channel Accessory
2653:Membrane transport protein
1336:Zimmermann–Laband syndrome
1319:missense mutations in the
615:potassium channel activity
4850:
4805:
4792:
3990:
3977:
3239:
3223:
3039:Epithelial sodium channel
3027:
3011:
2684:
2668:
1833:10.1007/s00439-015-1590-1
1787:10.1186/s12881-016-0304-4
1432:"Mouse PubMed Reference:"
1414:"Human PubMed Reference:"
1307:Temple–Baraitser syndrome
1305:and colleagues described
1228:
1223:
1219:
1212:
1196:
1190:Chr 1: 191.87 – 192.19 Mb
1183:Chr 1: 210.68 – 211.13 Mb
1177:
1158:
1133:
1122:
1103:
1078:
1067:
1054:
1050:
1035:
1031:
1022:
1009:
1005:
990:
986:
977:
964:
960:
945:
941:
932:
917:
910:
906:
890:
786:potassium channel complex
645:identical protein binding
605:cyclic nucleotide binding
575:
571:
554:
545:
536:
523:
472:
463:
442:anterior cingulate cortex
410:
401:
371:
363:
359:
342:
329:
292:
271:
262:
258:
241:
228:
191:
168:
159:
155:
110:
107:
97:
90:
85:
66:
61:
44:
39:
34:
30:
26:
21:
2956:Cation channels of sperm
2560:Medical Subject Headings
2556:Kv10.1+Potassium+Channel
2550:Medical Subject Headings
2016:10.1093/emboj/19.13.3263
1973:10.1093/emboj/18.20.5540
1939:10.1074/jbc.273.36.23080
1267:KCNH1 has been shown to
2430:10.3748/wjg.v13.i8.1257
2385:10.1073/pnas.0609278104
1493:Pharmacological Reviews
827:potassium ion transport
817:transmembrane transport
716:early endosome membrane
4942:Membrane protein stubs
4881:–related article is a
2566:Human Disease Genes -
2332:10.1186/1476-4598-5-42
2297:10.1074/jbc.M600883200
2217:10.1124/mol.104.006577
2205:Molecular Pharmacology
2140:10.1073/pnas.122617999
2060:10.1074/jbc.M108211200
1894:10.1073/pnas.91.8.3438
1578:10.1073/pnas.122617999
701:nuclear inner membrane
665:14-3-3 protein binding
650:protein kinase binding
512:superior frontal gyrus
508:lumbar spinal ganglion
3032:Constitutively active
766:postsynaptic membrane
430:cerebellar hemisphere
2546:KCNH1+protein,+human
1774:BMC Medical Genetics
1642:10.1002/ajmg.a.32129
1311:clinical geneticists
741:postsynaptic density
706:presynaptic membrane
610:ion channel activity
496:primary motor cortex
287:Chromosome 1 (mouse)
185:Chromosome 1 (human)
62:List of PDB id codes
35:Available structures
4799:By gating mechanism
2376:2007PNAS..104.3943O
2290:(19): 13030–13037.
2131:2002PNAS...99.7986O
2053:(16): 13673–13681.
1932:(36): 23080–23085.
1885:1994PNAS...91.3438W
1569:2002PNAS...99.7986O
832:signal transduction
4326:TRP cation channel
4224:CNG cation channel
3507:Tandem pore domain
2718:Ryanodine receptor
2614:, which is in the
1505:10.1124/pr.57.4.10
1012:ENSMUSG00000058248
810:Biological process
791:neuronal cell body
674:Cellular component
600:calmodulin binding
583:Molecular function
484:olfactory tubercle
480:epithelium of lens
426:right frontal lobe
4894:
4893:
4862:
4861:
4846:
4845:
4842:
4841:
4834:Stretch-activated
4811:Ion channel class
4788:
4787:
4784:
4783:
3973:
3972:
3969:
3968:
3245:Calcium-activated
3233:Potassium channel
3219:
3218:
3215:
3214:
3007:
3006:
3003:
3002:
2606:
2605:
2477:10.1002/jcp.21065
2370:(10): 3943–3948.
2174:(19): 6996–7001.
2125:(12): 7986–7991.
2010:(13): 3263–3271.
1967:(20): 5540–5547.
1827:(10): 1089–1097.
1563:(12): 7986–7991.
1239:
1238:
1235:
1234:
1208:
1207:
1173:
1172:
1148:
1147:
1118:
1117:
1093:
1092:
1063:
1062:
1044:
1043:
1018:
1017:
999:
998:
973:
972:
954:
953:
902:
901:
567:
566:
563:
562:
532:
531:
519:
518:
500:nucleus accumbens
457:
456:
418:prefrontal cortex
355:
354:
254:
253:
149:KCNH1 - orthologs
81:
80:
77:
76:
45:Ortholog search:
4949:
4915:
4908:
4901:
4879:membrane protein
4873:
4866:
4807:
4794:
4002:Chloride channel
3992:
3979:
3372:Inward-rectifier
3241:
3225:
3029:
3013:
2983:Two-pore channel
2686:
2670:
2646:
2639:
2632:
2623:
2575:
2534:
2496:
2462:
2452:
2442:
2432:
2423:(8): 1257–1261.
2407:
2397:
2387:
2354:
2344:
2334:
2319:Molecular Cancer
2309:
2299:
2274:
2249:(5): 1074–1086.
2243:The FEBS Journal
2236:
2199:
2162:
2152:
2142:
2109:
2084:(2–3): 204–208.
2072:
2062:
2037:
2027:
2004:The EMBO Journal
1994:
1984:
1961:The EMBO Journal
1951:
1941:
1916:
1906:
1896:
1879:(8): 3438–3442.
1853:
1852:
1816:
1810:
1809:
1799:
1789:
1765:
1759:
1758:
1740:
1712:
1706:
1705:
1668:
1662:
1661:
1625:
1619:
1618:
1607:
1601:
1600:
1590:
1580:
1548:
1542:
1541:
1534:
1525:
1524:
1487:
1481:
1480:
1470:
1461:(1–2): 177–182.
1446:
1440:
1439:
1428:
1422:
1421:
1410:
1404:
1394:
1383:
1373:
1221:
1220:
1192:
1185:
1168:
1152:
1143:
1127:
1123:RefSeq (protein)
1113:
1097:
1088:
1072:
1048:
1029:
1003:
984:
958:
939:
908:
872:startle response
573:
559:
550:
543:
528:
476:secondary oocyte
468:
466:Top expressed in
461:
406:
404:Top expressed in
399:
378:
361:
351:
338:
327:
312:
305:
299:
288:
276:
260:
250:
237:
226:
211:
204:
198:
187:
173:
157:
151:
102:
95:
72:
59:
53:
32:
31:
19:
4957:
4956:
4952:
4951:
4950:
4948:
4947:
4946:
4922:
4921:
4920:
4919:
4863:
4858:
4838:
4801:
4780:
4629:
4528:
4518:
4314:
4212:
4188:
3986:
3965:
3879:
3756:
3613:
3596:
3501:
3465:
3435:
3391:
3383:
3366:
3320:
3235:
3211:
3184:
3123:
3106:
3065:
3023:
2999:
2882:
2854:
2841:
2828:
2808:
2795:
2760:
2739:
2680:
2678:Calcium channel
2664:
2650:
2607:
2602:
2601:
2586:
2542:
2537:
2515:10.1038/ng.3153
2503:Nature Genetics
2499:
2460:
2455:
2410:
2357:
2312:
2277:
2239:
2202:
2168:Cancer Research
2165:
2112:
2075:
2040:
1997:
1954:
1919:
1866:
1862:
1860:Further reading
1857:
1856:
1818:
1817:
1813:
1767:
1766:
1762:
1729:10.1038/ng.3282
1717:Nature Genetics
1714:
1713:
1709:
1686:10.1038/ng.3153
1674:Nature Genetics
1670:
1669:
1665:
1627:
1626:
1622:
1609:
1608:
1604:
1550:
1549:
1545:
1536:
1535:
1528:
1489:
1488:
1484:
1448:
1447:
1443:
1430:
1429:
1425:
1412:
1411:
1407:
1395:
1386:
1374:
1365:
1360:
1348:
1300:
1281:
1265:
1230:View/Edit Mouse
1225:View/Edit Human
1188:
1181:
1178:Location (UCSC)
1164:
1160:
1139:
1135:
1109:
1105:
1084:
1080:
993:ENSG00000143473
886:
857:myoblast fusion
805:
751:cell projection
726:plasma membrane
669:
625:protein binding
555:
524:
515:
510:
506:
502:
498:
494:
490:
486:
482:
478:
464:
453:
448:
446:caudate nucleus
444:
440:
438:cingulate gyrus
436:
432:
428:
424:
420:
416:
414:Brodmann area 9
402:
346:
333:
325:
315:
314:
313:
306:
286:
263:Gene location (
245:
232:
224:
214:
213:
212:
205:
183:
160:Gene location (
111:
98:
91:
68:
46:
17:
12:
11:
5:
4955:
4953:
4945:
4944:
4939:
4934:
4924:
4923:
4918:
4917:
4910:
4903:
4895:
4892:
4891:
4874:
4860:
4859:
4851:
4848:
4847:
4844:
4843:
4840:
4839:
4837:
4836:
4831:
4826:
4821:
4815:
4813:
4803:
4802:
4797:
4790:
4789:
4786:
4785:
4782:
4781:
4779:
4778:
4773:
4772:
4771:
4770:
4769:
4764:
4759:
4751:
4750:
4749:
4744:
4739:
4731:
4730:
4729:
4724:
4719:
4714:
4709:
4704:
4699:
4691:
4690:
4689:
4684:
4679:
4674:
4669:
4664:
4659:
4645:
4643:
4631:
4630:
4628:
4627:
4622:
4621:
4620:
4615:
4610:
4600:
4599:
4598:
4593:
4588:
4583:
4578:
4573:
4568:
4563:
4558:
4553:
4542:
4540:
4526:
4520:
4519:
4517:
4516:
4515:
4514:
4509:
4504:
4499:
4494:
4489:
4479:
4478:
4477:
4472:
4462:
4457:
4456:
4455:
4450:
4445:
4435:
4434:
4433:
4428:
4423:
4418:
4413:
4408:
4403:
4398:
4388:
4387:
4386:
4381:
4376:
4371:
4366:
4361:
4356:
4351:
4341:
4330:
4328:
4316:
4315:
4313:
4312:
4311:
4310:
4305:
4300:
4295:
4290:
4278:
4277:
4276:
4271:
4266:
4256:
4255:
4254:
4249:
4244:
4239:
4228:
4226:
4214:
4213:
4211:
4210:
4204:
4202:
4200:Proton channel
4190:
4189:
4187:
4186:
4185:
4184:
4179:
4169:
4168:
4167:
4162:
4157:
4152:
4147:
4142:
4137:
4127:
4126:
4125:
4120:
4115:
4110:
4105:
4100:
4095:
4090:
4085:
4075:
4070:
4069:
4068:
4067:
4066:
4061:
4056:
4051:
4041:
4040:
4039:
4034:
4024:
4023:
4022:
4006:
4004:
3988:
3987:
3982:
3975:
3974:
3971:
3970:
3967:
3966:
3964:
3963:
3958:
3957:
3956:
3951:
3946:
3936:
3931:
3926:
3925:
3924:
3919:
3914:
3909:
3899:
3898:
3897:
3892:
3887:
3877:
3872:
3871:
3870:
3869:
3864:
3859:
3852:
3851:
3850:
3845:
3840:
3833:
3832:
3831:
3826:
3819:
3818:
3817:
3812:
3807:
3800:
3799:
3798:
3793:
3786:
3785:
3784:
3779:
3774:
3769:
3764:
3754:
3749:
3748:
3747:
3746:
3741:
3736:
3731:
3724:
3723:
3722:
3715:
3714:
3713:
3708:
3703:
3696:
3695:
3694:
3689:
3684:
3679:
3672:
3671:
3670:
3665:
3658:
3657:
3656:
3651:
3646:
3641:
3636:
3631:
3626:
3621:
3611:
3606:
3604:
3598:
3597:
3595:
3594:
3593:
3592:
3587:
3582:
3577:
3572:
3567:
3562:
3557:
3552:
3547:
3542:
3537:
3532:
3527:
3522:
3511:
3509:
3503:
3502:
3500:
3499:
3498:
3497:
3492:
3487:
3482:
3477:
3472:
3463:
3459:
3458:
3457:
3452:
3447:
3442:
3433:
3425:
3424:
3423:
3418:
3413:
3408:
3403:
3398:
3389:
3385:
3381:
3376:
3374:
3368:
3367:
3365:
3364:
3363:
3362:
3357:
3352:
3347:
3342:
3337:
3332:
3327:
3318:
3314:
3313:
3312:
3304:
3303:
3302:
3297:
3292:
3282:
3281:
3280:
3275:
3270:
3265:
3260:
3249:
3247:
3237:
3236:
3228:
3221:
3220:
3217:
3216:
3213:
3212:
3210:
3209:
3208:
3207:
3202:
3197:
3192:
3182:
3178:
3177:
3176:
3171:
3166:
3161:
3156:
3151:
3146:
3141:
3136:
3131:
3121:
3116:
3114:
3108:
3107:
3105:
3104:
3103:
3102:
3097:
3092:
3087:
3076:
3074:
3067:
3066:
3064:
3063:
3062:
3061:
3056:
3051:
3046:
3035:
3033:
3025:
3024:
3021:Sodium channel
3016:
3009:
3008:
3005:
3004:
3001:
3000:
2998:
2997:
2996:
2995:
2990:
2980:
2979:
2978:
2973:
2968:
2963:
2952:
2951:
2950:
2949:
2944:
2939:
2934:
2924:
2923:
2922:
2917:
2912:
2907:
2897:
2896:
2895:
2890:
2880:
2875:
2874:
2873:
2872:
2867:
2862:
2852:
2844:
2839:
2831:
2826:
2818:
2817:
2816:
2806:
2798:
2793:
2785:
2784:
2783:
2778:
2773:
2768:
2758:
2749:
2747:
2741:
2740:
2738:
2737:
2736:
2735:
2730:
2725:
2715:
2714:
2713:
2708:
2703:
2692:
2690:
2682:
2681:
2673:
2666:
2665:
2651:
2649:
2648:
2641:
2634:
2626:
2604:
2603:
2600:
2599:
2587:
2582:
2581:
2579:
2578:Classification
2572:
2571:
2563:
2553:
2541:
2540:External links
2538:
2536:
2535:
2497:
2471:(3): 690–701.
2453:
2408:
2355:
2310:
2275:
2237:
2211:(3): 827–836.
2200:
2163:
2110:
2073:
2038:
1995:
1952:
1917:
1863:
1861:
1858:
1855:
1854:
1821:Human Genetics
1811:
1760:
1723:(6): 661–667.
1707:
1663:
1636:(4): 450–452.
1620:
1602:
1543:
1526:
1499:(4): 473–508.
1482:
1441:
1423:
1405:
1384:
1362:
1361:
1359:
1356:
1355:
1354:
1347:
1344:
1299:
1296:
1280:
1277:
1264:
1261:
1237:
1236:
1233:
1232:
1227:
1217:
1216:
1210:
1209:
1206:
1205:
1203:
1201:
1194:
1193:
1186:
1179:
1175:
1174:
1171:
1170:
1156:
1155:
1149:
1146:
1145:
1131:
1130:
1124:
1120:
1119:
1116:
1115:
1101:
1100:
1094:
1091:
1090:
1076:
1075:
1069:
1065:
1064:
1061:
1060:
1052:
1051:
1045:
1042:
1041:
1033:
1032:
1026:
1020:
1019:
1016:
1015:
1007:
1006:
1000:
997:
996:
988:
987:
981:
975:
974:
971:
970:
962:
961:
955:
952:
951:
943:
942:
936:
930:
929:
924:
919:
915:
914:
904:
903:
900:
899:
888:
887:
885:
884:
879:
874:
869:
864:
859:
854:
849:
844:
839:
834:
829:
824:
819:
813:
811:
807:
806:
804:
803:
798:
793:
788:
783:
778:
773:
768:
763:
758:
753:
748:
743:
738:
733:
728:
723:
718:
713:
708:
703:
698:
693:
688:
683:
677:
675:
671:
670:
668:
667:
662:
657:
652:
647:
642:
637:
632:
627:
622:
617:
612:
607:
602:
597:
592:
586:
584:
580:
579:
569:
568:
565:
564:
561:
560:
552:
551:
540:
534:
533:
530:
529:
521:
520:
517:
516:
514:
513:
509:
505:
501:
497:
493:
492:primary oocyte
489:
485:
481:
477:
473:
470:
469:
458:
455:
454:
452:
451:
447:
443:
439:
435:
431:
427:
423:
419:
415:
411:
408:
407:
395:
394:
386:
375:
369:
368:
365:RNA expression
357:
356:
353:
352:
344:
340:
339:
331:
328:
323:
317:
316:
307:
300:
294:
290:
289:
284:
278:
277:
269:
268:
256:
255:
252:
251:
243:
239:
238:
230:
227:
222:
216:
215:
206:
199:
193:
189:
188:
181:
175:
174:
166:
165:
153:
152:
109:
105:
104:
96:
88:
87:
83:
82:
79:
78:
75:
74:
64:
63:
55:
54:
43:
37:
36:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
4954:
4943:
4940:
4938:
4935:
4933:
4930:
4929:
4927:
4916:
4911:
4909:
4904:
4902:
4897:
4896:
4890:
4888:
4884:
4880:
4875:
4872:
4868:
4857:
4856:
4849:
4835:
4832:
4830:
4829:Voltage-gated
4827:
4825:
4822:
4820:
4817:
4816:
4814:
4812:
4808:
4804:
4800:
4795:
4791:
4777:
4774:
4768:
4765:
4763:
4760:
4758:
4755:
4754:
4752:
4748:
4745:
4743:
4740:
4738:
4735:
4734:
4732:
4728:
4725:
4723:
4720:
4718:
4715:
4713:
4710:
4708:
4705:
4703:
4700:
4698:
4695:
4694:
4692:
4688:
4685:
4683:
4680:
4678:
4675:
4673:
4670:
4668:
4665:
4663:
4660:
4658:
4655:
4654:
4652:
4651:
4650:
4647:
4646:
4644:
4642:
4639:
4637:
4632:
4626:
4623:
4619:
4616:
4614:
4611:
4609:
4606:
4605:
4604:
4601:
4597:
4594:
4592:
4589:
4587:
4584:
4582:
4579:
4577:
4574:
4572:
4569:
4567:
4564:
4562:
4559:
4557:
4554:
4552:
4549:
4548:
4547:
4544:
4543:
4541:
4539:
4536:
4534:
4530:
4521:
4513:
4510:
4508:
4505:
4503:
4500:
4498:
4495:
4493:
4490:
4488:
4485:
4484:
4483:
4480:
4476:
4473:
4471:
4468:
4467:
4466:
4463:
4461:
4458:
4454:
4451:
4449:
4446:
4444:
4441:
4440:
4439:
4436:
4432:
4429:
4427:
4424:
4422:
4419:
4417:
4414:
4412:
4409:
4407:
4404:
4402:
4399:
4397:
4394:
4393:
4392:
4389:
4385:
4382:
4380:
4377:
4375:
4372:
4370:
4367:
4365:
4362:
4360:
4357:
4355:
4352:
4350:
4347:
4346:
4345:
4342:
4339:
4335:
4332:
4331:
4329:
4327:
4324:
4322:
4317:
4309:
4306:
4304:
4301:
4299:
4296:
4294:
4291:
4289:
4286:
4285:
4284:
4283:
4279:
4275:
4272:
4270:
4267:
4265:
4262:
4261:
4260:
4257:
4253:
4250:
4248:
4245:
4243:
4240:
4238:
4235:
4234:
4233:
4230:
4229:
4227:
4225:
4222:
4220:
4215:
4209:
4206:
4205:
4203:
4201:
4198:
4196:
4191:
4183:
4180:
4178:
4175:
4174:
4173:
4170:
4166:
4163:
4161:
4158:
4156:
4153:
4151:
4148:
4146:
4143:
4141:
4138:
4136:
4133:
4132:
4131:
4128:
4124:
4121:
4119:
4116:
4114:
4111:
4109:
4106:
4104:
4101:
4099:
4096:
4094:
4091:
4089:
4086:
4084:
4081:
4080:
4079:
4076:
4074:
4071:
4065:
4062:
4060:
4057:
4055:
4052:
4050:
4047:
4046:
4045:
4042:
4038:
4035:
4033:
4030:
4029:
4028:
4025:
4021:
4018:
4017:
4016:
4013:
4012:
4011:
4008:
4007:
4005:
4003:
4000:
3998:
3993:
3989:
3985:
3984:Miscellaneous
3980:
3976:
3962:
3961:Shaker (gene)
3959:
3955:
3952:
3950:
3947:
3945:
3942:
3941:
3940:
3937:
3935:
3934:minK/ISK-like
3932:
3930:
3927:
3923:
3920:
3918:
3915:
3913:
3910:
3908:
3905:
3904:
3903:
3900:
3896:
3893:
3891:
3888:
3886:
3883:
3882:
3881:
3874:
3873:
3868:
3865:
3863:
3860:
3858:
3855:
3854:
3853:
3849:
3846:
3844:
3841:
3839:
3836:
3835:
3834:
3830:
3827:
3825:
3822:
3821:
3820:
3816:
3813:
3811:
3808:
3806:
3803:
3802:
3801:
3797:
3794:
3792:
3789:
3788:
3787:
3783:
3780:
3778:
3775:
3773:
3770:
3768:
3765:
3763:
3760:
3759:
3758:
3751:
3750:
3745:
3742:
3740:
3737:
3735:
3732:
3730:
3727:
3726:
3725:
3721:
3718:
3717:
3716:
3712:
3709:
3707:
3704:
3702:
3699:
3698:
3697:
3693:
3690:
3688:
3685:
3683:
3680:
3678:
3675:
3674:
3673:
3669:
3666:
3664:
3661:
3660:
3659:
3655:
3652:
3650:
3647:
3645:
3642:
3640:
3637:
3635:
3632:
3630:
3627:
3625:
3622:
3620:
3617:
3616:
3615:
3608:
3607:
3605:
3603:
3602:Voltage-gated
3599:
3591:
3588:
3586:
3583:
3581:
3578:
3576:
3573:
3571:
3568:
3566:
3563:
3561:
3558:
3556:
3553:
3551:
3548:
3546:
3543:
3541:
3538:
3536:
3533:
3531:
3528:
3526:
3523:
3521:
3518:
3517:
3516:
3513:
3512:
3510:
3508:
3504:
3496:
3493:
3491:
3488:
3486:
3483:
3481:
3478:
3476:
3473:
3471:
3468:
3467:
3466:
3460:
3456:
3453:
3451:
3448:
3446:
3443:
3441:
3438:
3437:
3436:
3429:
3426:
3422:
3419:
3417:
3414:
3412:
3409:
3407:
3404:
3402:
3399:
3397:
3394:
3393:
3392:
3386:
3384:
3378:
3377:
3375:
3373:
3369:
3361:
3358:
3356:
3353:
3351:
3348:
3346:
3343:
3341:
3338:
3336:
3333:
3331:
3328:
3326:
3323:
3322:
3321:
3315:
3311:
3308:
3307:
3305:
3301:
3298:
3296:
3293:
3291:
3288:
3287:
3286:
3283:
3279:
3276:
3274:
3271:
3269:
3266:
3264:
3261:
3259:
3256:
3255:
3254:
3251:
3250:
3248:
3246:
3242:
3238:
3234:
3231:
3226:
3222:
3206:
3203:
3201:
3198:
3196:
3193:
3191:
3188:
3187:
3186:
3179:
3175:
3172:
3170:
3167:
3165:
3162:
3160:
3157:
3155:
3152:
3150:
3147:
3145:
3142:
3140:
3137:
3135:
3132:
3130:
3127:
3126:
3125:
3118:
3117:
3115:
3113:
3112:Voltage-gated
3109:
3101:
3098:
3096:
3093:
3091:
3088:
3086:
3083:
3082:
3081:
3078:
3077:
3075:
3072:
3068:
3060:
3057:
3055:
3052:
3050:
3047:
3045:
3042:
3041:
3040:
3037:
3036:
3034:
3030:
3026:
3022:
3019:
3014:
3010:
2994:
2991:
2989:
2986:
2985:
2984:
2981:
2977:
2974:
2972:
2969:
2967:
2964:
2962:
2959:
2958:
2957:
2954:
2953:
2948:
2945:
2943:
2940:
2938:
2935:
2933:
2930:
2929:
2928:
2925:
2921:
2918:
2916:
2913:
2911:
2908:
2906:
2903:
2902:
2901:
2898:
2894:
2891:
2889:
2886:
2885:
2884:
2877:
2876:
2871:
2868:
2866:
2863:
2861:
2858:
2857:
2856:
2848:
2845:
2843:
2835:
2832:
2830:
2822:
2819:
2815:
2812:
2811:
2810:
2802:
2799:
2797:
2789:
2786:
2782:
2779:
2777:
2774:
2772:
2769:
2767:
2764:
2763:
2762:
2754:
2751:
2750:
2748:
2746:
2745:Voltage-gated
2742:
2734:
2731:
2729:
2726:
2724:
2721:
2720:
2719:
2716:
2712:
2709:
2707:
2704:
2702:
2699:
2698:
2697:
2694:
2693:
2691:
2687:
2683:
2679:
2676:
2671:
2667:
2662:
2658:
2654:
2647:
2642:
2640:
2635:
2633:
2628:
2627:
2624:
2620:
2619:
2617:
2616:public domain
2613:
2598:
2594:
2593:
2589:
2588:
2585:
2580:
2576:
2570:
2569:
2564:
2561:
2557:
2554:
2551:
2547:
2544:
2543:
2539:
2532:
2528:
2524:
2520:
2516:
2512:
2508:
2504:
2498:
2494:
2490:
2486:
2482:
2478:
2474:
2470:
2466:
2459:
2454:
2450:
2446:
2441:
2436:
2431:
2426:
2422:
2418:
2414:
2409:
2405:
2401:
2396:
2391:
2386:
2381:
2377:
2373:
2369:
2365:
2361:
2356:
2352:
2348:
2343:
2338:
2333:
2328:
2324:
2320:
2316:
2311:
2307:
2303:
2298:
2293:
2289:
2285:
2281:
2276:
2272:
2268:
2264:
2260:
2256:
2252:
2248:
2244:
2238:
2234:
2230:
2226:
2222:
2218:
2214:
2210:
2206:
2201:
2197:
2193:
2189:
2185:
2181:
2177:
2173:
2169:
2164:
2160:
2156:
2151:
2146:
2141:
2136:
2132:
2128:
2124:
2120:
2116:
2111:
2107:
2103:
2099:
2095:
2091:
2087:
2083:
2079:
2074:
2070:
2066:
2061:
2056:
2052:
2048:
2044:
2039:
2035:
2031:
2026:
2021:
2017:
2013:
2009:
2005:
2001:
1996:
1992:
1988:
1983:
1978:
1974:
1970:
1966:
1962:
1958:
1953:
1949:
1945:
1940:
1935:
1931:
1927:
1923:
1918:
1914:
1910:
1905:
1900:
1895:
1890:
1886:
1882:
1878:
1874:
1870:
1865:
1864:
1859:
1850:
1846:
1842:
1838:
1834:
1830:
1826:
1822:
1815:
1812:
1807:
1803:
1798:
1793:
1788:
1783:
1779:
1775:
1771:
1764:
1761:
1756:
1752:
1748:
1744:
1739:
1734:
1730:
1726:
1722:
1718:
1711:
1708:
1703:
1699:
1695:
1691:
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1683:
1679:
1675:
1667:
1664:
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1655:
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1647:
1643:
1639:
1635:
1631:
1624:
1621:
1616:
1612:
1606:
1603:
1598:
1594:
1589:
1584:
1579:
1574:
1570:
1566:
1562:
1558:
1554:
1547:
1544:
1539:
1533:
1531:
1527:
1522:
1518:
1514:
1510:
1506:
1502:
1498:
1494:
1486:
1483:
1478:
1474:
1469:
1464:
1460:
1456:
1452:
1445:
1442:
1437:
1433:
1427:
1424:
1419:
1415:
1409:
1406:
1402:
1398:
1393:
1391:
1389:
1385:
1381:
1377:
1372:
1370:
1368:
1364:
1357:
1353:
1350:
1349:
1345:
1343:
1341:
1337:
1332:
1330:
1326:
1322:
1318:
1317:
1312:
1308:
1304:
1297:
1295:
1293:
1289:
1286:
1278:
1276:
1274:
1270:
1262:
1260:
1256:
1254:
1251:
1247:
1243:
1231:
1226:
1222:
1218:
1215:
1211:
1204:
1202:
1199:
1195:
1191:
1187:
1184:
1180:
1176:
1169:
1167:
1163:
1157:
1153:
1150:
1144:
1142:
1138:
1132:
1128:
1125:
1121:
1114:
1112:
1108:
1102:
1098:
1095:
1089:
1087:
1083:
1077:
1073:
1070:
1068:RefSeq (mRNA)
1066:
1059:
1058:
1053:
1049:
1046:
1040:
1039:
1034:
1030:
1027:
1025:
1021:
1014:
1013:
1008:
1004:
1001:
995:
994:
989:
985:
982:
980:
976:
969:
968:
963:
959:
956:
950:
949:
944:
940:
937:
935:
931:
928:
925:
923:
920:
916:
913:
909:
905:
898:
894:
889:
883:
880:
878:
875:
873:
870:
868:
865:
863:
860:
858:
855:
853:
850:
848:
847:ion transport
845:
843:
840:
838:
835:
833:
830:
828:
825:
823:
820:
818:
815:
814:
812:
809:
808:
802:
799:
797:
794:
792:
789:
787:
784:
782:
779:
777:
774:
772:
769:
767:
764:
762:
759:
757:
754:
752:
749:
747:
746:cell junction
744:
742:
739:
737:
734:
732:
729:
727:
724:
722:
719:
717:
714:
712:
709:
707:
704:
702:
699:
697:
694:
692:
689:
687:
684:
682:
679:
678:
676:
673:
672:
666:
663:
661:
658:
656:
653:
651:
648:
646:
643:
641:
638:
636:
633:
631:
630:lipid binding
628:
626:
623:
621:
618:
616:
613:
611:
608:
606:
603:
601:
598:
596:
593:
591:
588:
587:
585:
582:
581:
578:
577:Gene ontology
574:
570:
558:
553:
549:
544:
541:
539:
535:
527:
522:
511:
507:
503:
499:
495:
491:
487:
483:
479:
475:
474:
471:
467:
462:
459:
449:
445:
441:
437:
433:
429:
425:
421:
417:
413:
412:
409:
405:
400:
397:
396:
393:
391:
387:
385:
384:
380:
379:
376:
374:
370:
366:
362:
358:
350:
345:
341:
337:
332:
322:
318:
311:
304:
298:
291:
283:
279:
275:
270:
266:
261:
257:
249:
244:
240:
236:
231:
221:
217:
210:
203:
197:
190:
186:
180:
176:
172:
167:
163:
158:
154:
150:
146:
142:
138:
134:
130:
126:
122:
118:
114:
106:
101:
94:
89:
84:
73:
71:
65:
60:
57:
56:
52:
49:
42:
38:
33:
29:
25:
20:
4887:expanding it
4876:
4852:
4819:Ligand-gated
4810:
4798:
4641:Gap junction
4634:
4523:
4319:
4280:
4258:
4231:
4217:
4193:
4171:
4129:
4077:
4043:
4026:
4014:
3995:
3983:
3938:
3901:
3875:
3823:
3752:
3609:
3514:
3461:
3431:
3387:
3316:
3229:
3180:
3119:
3017:
2926:
2899:
2878:
2850:
2837:
2824:
2804:
2791:
2756:
2689:Ligand-gated
2674:
2657:ion channels
2609:
2608:
2590:
2567:
2509:(1): 73–77.
2506:
2502:
2468:
2464:
2420:
2416:
2367:
2363:
2322:
2318:
2287:
2283:
2246:
2242:
2208:
2204:
2171:
2167:
2122:
2118:
2081:
2078:FEBS Letters
2077:
2050:
2046:
2007:
2003:
1964:
1960:
1929:
1925:
1876:
1872:
1824:
1820:
1814:
1777:
1773:
1763:
1720:
1716:
1710:
1680:(1): 73–77.
1677:
1673:
1666:
1633:
1629:
1623:
1614:
1605:
1560:
1556:
1546:
1496:
1492:
1485:
1458:
1455:FEBS Letters
1454:
1444:
1435:
1426:
1417:
1408:
1339:
1333:
1320:
1314:
1301:
1284:
1282:
1266:
1263:Interactions
1257:
1249:
1241:
1240:
1162:NP_001033696
1159:
1134:
1107:NM_001038607
1104:
1079:
1055:
1036:
1010:
991:
965:
946:
926:
921:
776:cell surface
388:
381:
347:192,192,467
334:191,873,082
246:211,134,165
233:210,676,823
108:External IDs
67:
4824:Light-gated
3306:IK channel
1738:2108/118197
1298:Pathologies
326:1|1 H6
86:Identifiers
4926:Categories
4027:Bestrophin
3285:SK channel
3253:BK channel
2927:γ-subunits
2900:β-subunits
2883:δ-subunits
1403:, May 2017
1382:, May 2017
1358:References
756:perikaryon
392:(ortholog)
129:HomoloGene
4855:disorders
4853:see also
4636:Cytoplasm
4546:Aquaporin
4015:Anoctamin
3838:11.1/hERG
1780:(1): 42.
1521:219195192
1329:mosaicism
1166:NP_034730
1141:NP_758872
1137:NP_002229
1111:NM_010600
1086:NM_172362
1082:NM_002238
912:Orthologs
137:GeneCards
4649:Connexin
3929:minK/ISK
2531:52799681
2523:25420144
2493:39833770
2485:17520698
2449:17451210
2404:17360457
2351:17022811
2306:16537547
2271:26926041
2263:16478480
2233:35049797
2225:15548764
2188:15466192
2159:12060745
2098:11943152
2069:11834728
2034:10880439
1991:10523298
1849:14238362
1841:26264464
1806:27282200
1755:12060592
1747:25915598
1702:52799681
1694:25420144
1650:18203178
1597:12060745
1513:16382104
1399:–
1378:–
1346:See also
1279:Function
1269:interact
1214:Wikidata
891:Sources:
781:axolemma
731:endosome
721:dendrite
711:membrane
422:testicle
4776:Innexin
4533:solutes
2440:4147004
2395:1820688
2372:Bibcode
2342:1618397
2196:6791131
2127:Bibcode
2106:8404036
1982:1171622
1948:9722534
1913:8159766
1881:Bibcode
1797:4901505
1658:2532859
1565:Bibcode
1477:9738473
1401:Ensembl
1380:Ensembl
1334:Type 1
1316:de novo
1303:Gabbett
1246:protein
1024:UniProt
979:Ensembl
918:Species
897:QuickGO
691:nucleus
681:synapse
367:pattern
125:1341721
93:Aliases
3073:-gated
3071:Proton
2847:T-type
2834:R-type
2821:Q-type
2801:P-type
2788:N-type
2753:L-type
2597:603305
2562:(MeSH)
2552:(MeSH)
2529:
2521:
2491:
2483:
2447:
2437:
2402:
2392:
2349:
2339:
2325:: 42.
2304:
2269:
2261:
2231:
2223:
2194:
2186:
2157:
2150:123007
2147:
2104:
2096:
2067:
2032:
2025:313935
2022:
1989:
1979:
1946:
1911:
1901:
1847:
1839:
1804:
1794:
1753:
1745:
1700:
1692:
1656:
1648:
1595:
1588:123007
1585:
1519:
1511:
1475:
1200:search
1198:PubMed
1057:Q60603
1038:O95259
934:Entrez
538:BioGPS
488:zygote
225:1q32.2
117:603305
4877:This
4687:GJA10
4538:Porin
4438:TRPML
4208:HVCN1
3902:KCNIP
3757:α7-12
2661:TC 1A
2568:KCNH1
2527:S2CID
2489:S2CID
2461:(PDF)
2267:S2CID
2229:S2CID
2192:S2CID
2102:S2CID
1904:43592
1845:S2CID
1751:S2CID
1698:S2CID
1654:S2CID
1517:S2CID
1340:KCNH1
1321:KCNH1
1285:KCNH1
1273:KCNB1
1271:with
1250:KCNH1
1244:is a
967:16510
927:Mouse
922:Human
893:Amigo
504:molar
450:gonad
390:Mouse
383:Human
330:Start
265:Mouse
229:Start
162:Human
141:KCNH1
133:68242
100:KCNH1
22:KCNH1
4883:stub
4767:GJD4
4762:GJD3
4757:GJD2
4747:GJC3
4742:GJC2
4737:GJC1
4727:GJB7
4722:GJB6
4717:GJB5
4712:GJB4
4707:GJB3
4702:GJB2
4697:GJB1
4682:GJA9
4677:GJA8
4672:GJA5
4667:GJA4
4662:GJA3
4657:GJA1
4482:TRPV
4465:TRPP
4460:TRPN
4391:TRPM
4344:TRPC
4334:TRPA
4172:CLNS
4130:CLIC
4078:CLCN
4073:CFTR
4020:ANO1
3939:MiRP
3867:12.3
3862:12.2
3857:12.1
3848:11.3
3843:11.2
3829:10.2
3824:10.1
3614:α1-6
3428:GIRK
2842:α2.3
2829:α2.1
2796:α2.2
2592:OMIM
2519:PMID
2481:PMID
2445:PMID
2400:PMID
2347:PMID
2302:PMID
2259:PMID
2221:PMID
2184:PMID
2155:PMID
2094:PMID
2065:PMID
2030:PMID
1987:PMID
1944:PMID
1909:PMID
1837:PMID
1802:PMID
1743:PMID
1690:PMID
1646:PMID
1634:146A
1593:PMID
1509:PMID
1473:PMID
1288:gene
1283:The
1253:gene
948:3756
696:axon
373:Bgee
321:Band
282:Chr.
220:Band
179:Chr.
113:OMIM
70:5J7E
51:RCSB
48:PDBe
4531:(+
4369:4AP
4282:HCN
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3810:9.2
3805:9.1
3796:8.2
3791:8.1
3782:7.5
3777:7.4
3772:7.3
3767:7.2
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3744:6.4
3739:6.3
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3668:2.2
3663:2.1
3654:1.8
3649:1.7
3644:1.6
3639:1.5
3634:1.4
3629:1.3
3624:1.2
3619:1.1
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3416:2.4
3411:2.3
3406:2.2
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3396:1.1
3382:ATP
3360:5.1
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3350:4.1
3345:3.1
3340:2.3
3335:2.2
3330:2.1
3325:1.1
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3300:SK3
3295:SK2
3290:SK1
3169:1.9
3164:1.8
3159:1.7
3154:1.6
3149:1.5
3144:1.4
3139:1.3
3134:1.2
3129:1.1
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2860:3.1
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2776:1.3
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2473:doi
2469:212
2435:PMC
2425:doi
2390:PMC
2380:doi
2368:104
2337:PMC
2327:doi
2292:doi
2288:281
2251:doi
2247:273
2213:doi
2176:doi
2145:PMC
2135:doi
2086:doi
2082:514
2055:doi
2051:277
2020:PMC
2012:doi
1977:PMC
1969:doi
1934:doi
1930:273
1899:PMC
1889:doi
1829:doi
1825:134
1792:PMC
1782:doi
1733:hdl
1725:doi
1682:doi
1638:doi
1583:PMC
1573:doi
1501:doi
1463:doi
1459:434
343:End
242:End
145:OMA
121:MGI
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4753:D
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4693:B
4653:A
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4288:FC
4182:1B
4177:1A
4165:L1
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4118:KA
3997:Cl
3590:18
3585:17
3580:16
3575:15
3570:13
3565:12
3560:10
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3278:β4
3273:β3
3268:β2
3263:β1
3258:α1
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3181:Na
3174:7A
3120:Na
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2942:γ3
2937:γ2
2932:γ1
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