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Vascular tumor

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vessels in lobules that are scattered in the skin, and that sometimes reach into the subcutaneous tissue, and have lymph vessels on the periphery. Their growth is slow to begin with, and progresses to a stable size. They show a high rate of spontaneous regression, particularly in congenital and early-onset cases. They typically have a deep nodular component sometimes extending into the subcutaneous tissue, fascia, and muscle, and can sometimes be painful. Tufted angiomas are associated with arteriovenous malformations.
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Johnson, EF; Davis, DM; Tollefson, MM; Fritchie, K; Gibson, LE (April 2018). "Vascular Tumors in Infants: Case Report and Review of Clinical, Histopathologic, and Immunohistochemical Characteristics of Infantile Hemangioma, Pyogenic Granuloma, Noninvoluting Congenital Hemangioma, Tufted Angioma, and
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Congenital hemangiomas are present and fully formed at birth, and only account for 2% of the hemangiomas. They do not have the postnatal phase of proliferation common to infantile hemangiomas. There are two main variants of congenital hemangioma: non-involuting, and rapidly involuting (beginning in
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are hereditary hemangiomas found in infants from birth to five years of age, however they may occur in adults. They are found on the neck, shoulders, and trunk as rounded nodules. Tufted angiomas are usually poorly defined lesions of purple colouration. The tumors are of tufts of capillary-sized
320:, that are more often found in children and young adults. These granulomas are well defined growths of less than a centimetre across. They are bright red due to being highly vascularised, and bleed and ulcerate easily. Their colouring fades with age. 239:
seems to be a major trigger for this. Infantile hemangiomas are easily diagnosed, and little if any aggressive treatment is needed. They are characterised by rapid growth in the first few months, followed by spontaneous regression in early childhood.
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KHE is characterised by nodules of tumor-like spindled endothelial cells. Unlike infantile hemangiomas, KHEs have a high mortality rate. Both KHEs and TAs are unique in that they carry the risk of the development of
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van Vugt, LJ; van der Vleuten, CJM; Flucke, U; Blokx, WAM (June 2017). "The utility of GLUT1 as a diagnostic marker in cutaneous vascular anomalies: A review of literature and recommendations for daily practice".
368:. KHEs are described as locally destructive because they can infiltrate underlying muscle and fat. They are often seen to overlap with tufted angiomas (TAs) but TAs may be a milder, benign counterpart. 447: 335:
The origin of tufted angiomas is not clear but markers on the cells suggest a possible derivation from the endothelial cells of lymph vessels. They are also associated with the local secretion of
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are the most common type of vascular tumor to affect babies, accounting for 90% of hemangiomas. They are characterised by the abnormal proliferation of endothelial cells and of deviant
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Darrow, DH; Greene, AK; Mancini, AJ; Nopper, AJ; SECTION ON DERMATOLOGY, SECTION ON OTOLARYNGOLOGY–HEAD AND NECK SURGERY, and SECTION ON PLASTIC, SURGERY. (October 2015).
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Victoria Martínez, AM; Cubells Sánchez, L; Esteve Martínez, A; Estela Cubells, JR; Febrer Bosch, I; Alegre de Miquel, V; Oliver Martínez, V (September 2015). "".
253:. Congenital hemangiomas can also be distinguished from infantile hemangiomas in that neither variant of congenital hemangioma expresses the glucose transporter 1213: 1133: 451: 1088: 1198: 1369: 1166: 170:. Vascular tumors can be further subclassified as being benign, borderline or aggressive, and malignant. Vascular tumors are described as 1250: 1343: 1159: 805: 957:
Putra, J; Gupta, A (June 2017). "Kaposiform haemangioendothelioma: a review with emphasis on histological differential diagnosis".
1193: 1138: 393: 1143: 1118: 903:"The importance of early diagnosis and treatment of kaposiform hemangioendothelioma complicated by Kasabach-Merritt phenomenon" 739: 1027:
Ghose, A; Guha, G; Kundu, R; Tew, J; Chaudhary, R (June 2017). "CNS Hemangiopericytoma: A Systematic Review of 523 Patients".
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Vivas-Colmenares, GV; Ramirez-Villar, GL; Bernabeu-Wittel, J; Matute de Cardenas, JA; Fernandez-Pineda, I (January 2015).
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Croteau, SE; Gupta, D (September 2016). "The clinical spectrum of kaposiform hemangioendothelioma and tufted angioma".
1338: 364:(KHEs) are borderline, locally destructive vascular tumors. They are named after their resemblance to the lesions of 421: 1357: 1294: 1074: 1245: 1321: 1284: 1240: 1208: 282: 663: 167: 1267: 1235: 1230: 1123: 348: 228: 223: 117: 70: 1188: 365: 353: 121: 1420: 1306: 1171: 1052: 883: 491: 397: 313: 17: 1374: 1333: 1044: 1009: 974: 932: 875: 801: 775: 721: 651: 601: 555: 483: 401: 236: 59: 1220: 1036: 1001: 966: 922: 914: 867: 767: 711: 701: 641: 591: 545: 537: 475: 278: 273: 261: 195: 186: 163: 129: 1113: 89: 1364: 1277: 1272: 1262: 927: 902: 716: 689: 550: 525: 328: 1414: 1289: 887: 371:
KHEs show as a red or purple expanding mass of soft tissue, found mostly in infants.
336: 105: 1056: 1399: 1394: 1329: 1105: 580:"Vascular Anomalies (Part I): Classification and Diagnostics of Vascular Anomalies" 495: 389: 232: 199: 140: 125: 113: 101: 93: 1040: 970: 871: 824: 479: 214:, most commonly infantile hemangiomas, and less commonly congenital hemangiomas. 1299: 1183: 1225: 771: 706: 298: 211: 109: 51: 1005: 584:
RöFo: Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
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Sadick, M; MĂĽller-Wille, R; Wildgruber, M; Wohlgemuth, WA (September 2018).
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Wildgruber, M; Sadick, M; MĂĽller-Wille, R; Wohlgemuth, WA (13 March 2019).
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that affect angiogenesis and promote the development of vascular lobules.
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A vascular tumor typically grows quickly by the proliferation of
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that grow in response to a stimulus, such as trauma, or a local
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the first year of life). A third variant is also recognised as
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The most common type of reactive proliferative tumors are
154:, referring to the degree of blood supply to the tumor. 264:. Rare cases have been associated with heart failure. 162:
Vascular tumors make up one of the classifications of
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Some cases have been associated with a mild form of
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A vascular tumor may be described in terms of being
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Some vascular tumors can be associated with serious
1383: 1320: 1104: 293:A range of benign vascular tumors are described as 210:The most common type of benign vascular tumors are 58: 35: 630:"Diagnosis and Management of Infantile Hemangioma" 526:"Classification of Vascular Anomalies: An Update" 388:Malignant vascular tumors are rare, and include 1312:Intravascular papillary endothelial hyperplasia 800:(Tenth ed.). Elsevier. pp. 392–396. 1082: 136:refers to any type of benign vascular tumor. 27:Tumor originating from blood or lymph vessels 8: 690:"Vascular tumors in infants and adolescents" 683: 681: 679: 668:: CS1 maint: multiple names: authors list ( 853: 851: 849: 847: 845: 1089: 1075: 1067: 994:Seminars in Cutaneous Medicine and Surgery 791: 789: 524:Steiner, JE; Drolet, BA (September 2017). 92:; a soft tissue growth that can be either 69: 41: 32: 926: 715: 705: 645: 595: 573: 571: 569: 549: 519: 517: 515: 513: 511: 509: 507: 505: 301:. They can also form infrequently during 952: 950: 948: 946: 623: 621: 619: 617: 615: 468:The American Journal of Dermatopathology 819: 817: 413: 1370:Multifocal lymphangioendotheliomatosis 907:Dermatology Practical & Conceptual 661: 108:. Examples of vascular tumors include 1029:American Journal of Clinical Oncology 796:Kumar, V; Abbas, A; Aster, J (2018). 448:"Dorlands Medical Dictionary:angioma" 305:as a hormonal reaction affecting the 143:, making correct diagnosis critical. 7: 1167:Proliferating angioendotheliomatosis 530:Seminars in Interventional Radiology 466:Kaposiform Hemangioendothelioma". 25: 1344:Acquired progressive lymphangioma 450:. 2 February 2009. Archived from 394:epithelioid hemangioendotheliomas 54:, a benign type of vascular tumor 760:Pathology, Research and Practice 422:"NCI Dictionary of Cancer Terms" 362:Kaposiform hemangioendotheliomas 190:A pyogenic granuloma on a thumb. 174:, and vascular malformations as 1119:Blue rubber bleb nevus syndrome 357:Kaposiform hemangioendothelioma 18:Kaposiform hemangioendothelioma 295:reactive proliferative lesions 1: 318:lobular capillary hemangiomas 1214:Immunosuppression-associated 1177:Infantile hemangiopericytoma 1041:10.1097/COC.0000000000000146 971:10.1016/j.pathol.2017.03.001 872:10.1016/j.anpedi.2014.10.018 480:10.1097/DAD.0000000000000983 1339:Lymphangioma circumscriptum 281:are vascular tumors of the 1442: 346: 271: 221: 772:10.1016/j.prp.2017.04.023 707:10.1186/s13244-019-0718-6 426:National Cancer Institute 378:Kasabach–Merritt syndrome 49: 40: 1358:Lymphangioleiomyomatosis 1199:African lymphadenopathic 1098:Tumours of blood vessels 1006:10.12788/j.sder.2016.048 740:"Congenital haemangioma" 166:. The other grouping is 141:blood-clotting disorders 798:Robbins basic pathology 1285:Universal angiomatosis 1251:Targeted hemosiderotic 1134:Endovascular papillary 647:10.1542/peds.2015-2485 542:10.1055/s-0037-1604295 358: 283:central nervous system 233:blood vessel formation 191: 168:vascular malformations 694:Insights into Imaging 356: 244:Congenital hemangioma 229:Infantile hemangiomas 189: 118:hemangioendotheliomas 1426:Anatomical pathology 1124:Hemangioendothelioma 373:Under the microscope 349:Hemangioendothelioma 251:partially involuting 224:Infantile hemangioma 218:Infantile hemangioma 919:10.5826/dpc.0501a18 860:Anales de Pediatria 597:10.1055/a-0620-8925 454:on 2 February 2009. 398:hemangiopericytomas 396:. Other types are 314:pyogenic granulomas 152:poorly vascularized 148:highly vascularized 1307:Pyogenic granuloma 1172:Hemangiopericytoma 402:lymphangiosarcomas 359: 289:Pyogenic granuloma 192: 164:vascular anomalies 1408: 1407: 1375:Lymphangiomatosis 1334:lymphangiosarcoma 1194:African cutaneous 829:meshb.nlm.nih.gov 428:. 2 February 2011 279:Hemangioblastomas 235:or architecture. 196:endothelial cells 130:hemangioblastomas 122:Kaposi's sarcomas 78: 77: 30:Medical condition 16:(Redirected from 1433: 1221:Hemangioblastoma 1189:Kaposi's sarcoma 1091: 1084: 1077: 1068: 1061: 1060: 1024: 1018: 1017: 989: 983: 982: 954: 941: 940: 930: 898: 892: 891: 855: 840: 839: 837: 835: 821: 812: 811: 793: 784: 783: 754: 748: 747: 736: 730: 729: 719: 709: 685: 674: 673: 667: 659: 649: 640:(4): e1060-104. 625: 610: 609: 599: 575: 564: 563: 553: 521: 500: 499: 462: 456: 455: 444: 438: 437: 435: 433: 418: 366:Kaposi's sarcoma 274:Hemangioblastoma 268:Hemangioblastoma 262:thrombocytopenia 176:nonproliferative 74: 73: 45: 33: 21: 1441: 1440: 1436: 1435: 1434: 1432: 1431: 1430: 1411: 1410: 1409: 1404: 1379: 1316: 1204:AIDS-associated 1114:Hemangiosarcoma 1100: 1095: 1065: 1064: 1026: 1025: 1021: 991: 990: 986: 956: 955: 944: 900: 899: 895: 857: 856: 843: 833: 831: 823: 822: 815: 808: 795: 794: 787: 756: 755: 751: 744:www.gosh.nhs.uk 738: 737: 733: 687: 686: 677: 660: 627: 626: 613: 577: 576: 567: 523: 522: 503: 464: 463: 459: 446: 445: 441: 431: 429: 420: 419: 415: 410: 386: 351: 345: 329:Tufted angiomas 326: 291: 276: 270: 246: 226: 220: 208: 198:. Most are not 184: 160: 90:vascular origin 68: 31: 28: 23: 22: 15: 12: 11: 5: 1439: 1437: 1429: 1428: 1423: 1413: 1412: 1406: 1405: 1403: 1402: 1397: 1387: 1385: 1381: 1380: 1378: 1377: 1372: 1367: 1365:Cystic hygroma 1362: 1361: 1360: 1348: 1347: 1346: 1341: 1326: 1324: 1318: 1317: 1315: 1314: 1309: 1304: 1303: 1302: 1297: 1287: 1282: 1281: 1280: 1275: 1270: 1265: 1255: 1254: 1253: 1248: 1243: 1238: 1233: 1223: 1218: 1217: 1216: 1211: 1206: 1201: 1196: 1186: 1181: 1180: 1179: 1169: 1164: 1163: 1162: 1157: 1151: 1146: 1141: 1136: 1131: 1121: 1116: 1110: 1108: 1102: 1101: 1096: 1094: 1093: 1086: 1079: 1071: 1063: 1062: 1035:(3): 223–227. 1019: 984: 965:(4): 356–362. 942: 893: 841: 825:"MeSH Browser" 813: 806: 785: 766:(6): 591–597. 749: 731: 675: 611: 590:(9): 825–835. 565: 536:(3): 225–232. 501: 474:(4): 231–239. 457: 439: 412: 411: 409: 406: 385: 382: 347:Main article: 344: 341: 337:growth factors 325: 324:Tufted angioma 322: 316:also known as 290: 287: 272:Main article: 269: 266: 245: 242: 237:Hypoxic stress 222:Main article: 219: 216: 207: 204: 183: 180: 159: 158:Classification 156: 100:, formed from 82:vascular tumor 76: 75: 62: 56: 55: 47: 46: 38: 37: 36:Vascular tumor 29: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 1438: 1427: 1424: 1422: 1419: 1418: 1416: 1401: 1398: 1396: 1392: 1389: 1388: 1386: 1382: 1376: 1373: 1371: 1368: 1366: 1363: 1359: 1356: 1355: 1354: 1353: 1349: 1345: 1342: 1340: 1337: 1336: 1335: 1331: 1328: 1327: 1325: 1323: 1319: 1313: 1310: 1308: 1305: 1301: 1298: 1296: 1293: 1292: 1291: 1290:Angiokeratoma 1288: 1286: 1283: 1279: 1276: 1274: 1271: 1269: 1266: 1264: 1261: 1260: 1259: 1256: 1252: 1249: 1247: 1244: 1242: 1239: 1237: 1234: 1232: 1229: 1228: 1227: 1224: 1222: 1219: 1215: 1212: 1210: 1207: 1205: 1202: 1200: 1197: 1195: 1192: 1191: 1190: 1187: 1185: 1182: 1178: 1175: 1174: 1173: 1170: 1168: 1165: 1161: 1158: 1155: 1152: 1150: 1147: 1145: 1142: 1140: 1137: 1135: 1132: 1130: 1127: 1126: 1125: 1122: 1120: 1117: 1115: 1112: 1111: 1109: 1107: 1103: 1099: 1092: 1087: 1085: 1080: 1078: 1073: 1072: 1069: 1058: 1054: 1050: 1046: 1042: 1038: 1034: 1030: 1023: 1020: 1015: 1011: 1007: 1003: 1000:(3): 147–52. 999: 995: 988: 985: 980: 976: 972: 968: 964: 960: 953: 951: 949: 947: 943: 938: 934: 929: 924: 920: 916: 912: 908: 904: 897: 894: 889: 885: 881: 877: 873: 869: 865: 861: 854: 852: 850: 848: 846: 842: 830: 826: 820: 818: 814: 809: 807:9780323353175 803: 799: 792: 790: 786: 781: 777: 773: 769: 765: 761: 753: 750: 745: 741: 735: 732: 727: 723: 718: 713: 708: 703: 699: 695: 691: 684: 682: 680: 676: 671: 665: 657: 653: 648: 643: 639: 635: 631: 624: 622: 620: 618: 616: 612: 607: 603: 598: 593: 589: 585: 581: 574: 572: 570: 566: 561: 557: 552: 547: 543: 539: 535: 531: 527: 520: 518: 516: 514: 512: 510: 508: 506: 502: 497: 493: 489: 485: 481: 477: 473: 469: 461: 458: 453: 449: 443: 440: 427: 423: 417: 414: 407: 405: 403: 399: 395: 391: 390:angiosarcomas 383: 381: 379: 374: 369: 367: 363: 355: 350: 342: 340: 338: 333: 330: 323: 321: 319: 315: 310: 308: 304: 300: 296: 288: 286: 284: 280: 275: 267: 265: 263: 258: 256: 252: 243: 241: 238: 234: 230: 225: 217: 215: 213: 205: 203: 201: 200:birth defects 197: 188: 181: 179: 177: 173: 172:proliferative 169: 165: 157: 155: 153: 149: 144: 142: 137: 135: 131: 127: 126:angiosarcomas 123: 119: 115: 114:lymphangiomas 111: 107: 106:lymph vessels 103: 102:blood vessels 99: 95: 91: 87: 83: 72: 66: 63: 61: 57: 53: 48: 44: 39: 34: 19: 1400:Angiofibroma 1395:angiosarcoma 1350: 1330:Lymphangioma 1246:Microvenular 1160:Spindle cell 1106:Blood vessel 1097: 1032: 1028: 1022: 997: 993: 987: 962: 958: 910: 906: 896: 866:(3): 201–8. 863: 859: 832:. 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Index

Kaposiform hemangioendothelioma

hemangioma
Specialty
Oncology
Edit this on Wikidata
tumor
vascular origin
benign
malignant
blood vessels
lymph vessels
hemangiomas
lymphangiomas
hemangioendotheliomas
Kaposi's sarcomas
angiosarcomas
hemangioblastomas
angioma
blood-clotting disorders
vascular anomalies
vascular malformations

endothelial cells
birth defects
hemangiomas
Infantile hemangioma
Infantile hemangiomas
blood vessel formation
Hypoxic stress

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