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Kary Mullis

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498:(with his girlfriend, who also was a chemist at Cetus), he had the idea to use a pair of primers to bracket the desired DNA sequence and to copy it using DNA polymerase; a technique that would allow rapid amplification of a small stretch of DNA and become a standard procedure in molecular biology laboratories. Longtime professional benefactor and supervisor Thomas White reassigned Mullis from his usual projects to concentrate on PCR full-time after the technique was met with skepticism by their colleagues. Mullis succeeded in demonstrating PCR on December 16, 1983, but the staff remained circumspect as he continued to produce ambiguous results amid alleged methodological problems, including a perceived lack of "appropriate controls and repetition." In his Nobel Prize lecture, he remarked that the December 16 breakthrough did not make up for his girlfriend breaking up with him: "I was sagging as I walked out to my little silver 513:, were placed on parallel PCR projects to work on determining if PCR could amplify a specific human gene (betaglobin) from genomic DNA. Saiki generated the needed data and Erlich authored the first paper to include use of the technique, while Mullis was still working on the paper that would describe PCR itself. Mullis's 1985 paper with Saiki and Erlich, "Enzymatic Amplification of β-globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia" — the polymerase chain reaction invention (PCR) — was honored by a Citation for Chemical Breakthrough Award from the Division of History of Chemistry of the American Chemical Society in 2017. 3471: 3443: 554:
alpha-1,3-galactosyl-galactose bonds. All humans are. Why not divert a fraction of those antibodies to the influenza strain you just picked up. A chemical linker synthesized with an alpha-1,3-gal-gal bond on one end and a DNA aptamer devised to bind specifically to the strain of influenza you have on the other end, will link anti-alpha-Gal antibodies to the influenza virus and presto, you have fooled your immune system into attacking the new virus.
1139: 1111: 598:. Using repair replication, Kleppe duplicated and then quadrupled a small synthetic molecule with the help of two primers and DNA polymerase. The method developed by Mullis used repeated thermal cycling, which allowed the rapid and exponential amplification of large quantities of any desired DNA sequence from an extremely complex template. Later a heat-stable DNA polymerase was incorporated into the process. 314:, on December 28, 1944, to Cecil Banks Mullis and Bernice Barker Mullis. His family had a background in farming in this rural area. As a child, Mullis said, he was interested in observing organisms in the countryside. He and his cousins would often taunt livestock by feeding them through electric fences, and Kary was mostly interested in the spiders in his grandparents' basement. He grew up in 1125: 3749: 660:. Mullis claimed that scientific theories about ozone depletion and climate change were the product of scientists and government bureaucrats conspiring to secure funding, saying that "science is being practiced by people who are dependent on being paid for what they are going to find out" instead of searching for the truth. 627:) that "prior art" (i.e. articles on the subject of Taq polymerase published by other groups prior to the work of Gelfand and Stoffel, and their patent application covering the purification of Taq polymerase) existed, in the form of two articles, published by Alice Chien et al. in 1976, and A. S. Kaledin et al. in 1980. 1097: 539:. … It’s impossible to overstate PCR’s impact. The ability to generate as much DNA of a specific sequence as you want, starting from a few simple chemicals and some temperature changes—it’s just magical." Although he received a $ 10,000 bonus from Cetus for the invention, the company's later sale of the patent to 3002:
Like Herbert, many scientists and engineers also report heightened states of creativity while using LSD. During a press conference on Friday, Hofmann revealed that he was told by Nobel-prize-winning chemist Kary Mullis that LSD had helped him develop the polymerase chain reaction that helps amplify
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and Paroma Basu to call him an AIDS denialist. He wrote that he began to question the AIDS consensus while compiling a report for a project's sponsor and being unable to find a published reference for HIV being the cause of AIDS. Mullis published an alternative hypothesis for AIDS in 1994, claiming
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lost out to Roche on that sale, the company unsuccessfully disputed Mullis's patent on the alleged grounds that PCR had been previously described in 1971. Mullis and Erlich took Cetus' side in the case, and Khorana refused to testify for DuPont; the jury upheld Mullis's patent in 1991. However, in
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Another proof-of-principle of this technology, re-targeting pre-existing antibodies to the surface of a pathogenic strep bacterium using an alpha-gal modified aptamer ("alphamer"), was published in 2015 in collaboration with scientists at the University of California, San Diego. Mullis said he was
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in 1968, he struggled to pass his oral exams (with a colleague recalling that "He didn’t get his propositions right. He didn’t know general biochemistry"), and his dissertation was accepted only after several friends pitched in to "cut all the whacko stuff out of it" while his advisor lobbied the
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After receiving his doctorate, Mullis briefly left science to write fiction before accepting the University of Kansas fellowship. During his postdoctoral work, he managed a bakery for two years. Mullis returned to science at the encouragement of UC Berkeley friend and colleague Thomas White, who
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states that Mullis's colleagues failed to see the potential of the technique when he presented it to them. As a result, some controversy surrounds the balance of credit that should be given to Mullis versus the team at Cetus. In practice, credit has accrued to both the inventor and the company
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It is a method using specific synthetic chemical linkers to divert an immune response from its nominal target to something completely different which you would right now like to be temporarily immune to. Let's say you just got exposed to a new strain of the flu. You’re already immune to
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Mullis acquired a reputation for erratic behavior at Cetus, once threatening to bring a gun to work; he also engaged in "public lovers' quarrels" with his then-girlfriend (a fellow chemist at the company) and "nearly came to blows with another scientist" at a staff party, according to
745:, Mullis said, "Back in the 1960s and early 1970s I took plenty of LSD. A lot of people were doing that in Berkeley back then. And I found it to be a mind-opening experience. It was certainly much more important than any courses I ever took." During a symposium held for centenarian 526:
to amplify segments of DNA. The Taq polymerase was heat resistant and needed to be added to the reaction only once, making the technique dramatically more affordable and subject to automation. This modification of Mullis's invention revolutionized biochemistry, molecular biology,
735:; according to his friend Tom White, "I knew he was a good chemist because he'd been synthesizing hallucinogenic drugs at UC Berkeley." He detailed his experiences synthesizing and testing various psychedelic amphetamines and a difficult trip on 367:
schizokinen. J. B. Neilands was known for his groundbreaking work on siderophores, and Mullis was a part of that with his characterization of schizokinen. Following his graduation, Mullis completed postdoctoral fellowships in pediatric
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Saiki, R.; Scharf, S.; Faloona, F.; Mullis, K.; Horn, G.; Erlich, H.; Arnheim, N (December 20, 1985). "Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia".
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as well as a musician, being both a guitarist and vocalist. He married four times, and he had three children by two of his wives. At the time of his death, he had two grandchildren and was survived by his fourth wife, Nancy
322:, graduating in the class of 1962. He recalled his interest in chemistry beginning when he learned how to chemically synthesize and build solid fuel propulsion rockets as a high school student during the 1960s. 996:, as well as providing insights into his opinions and experiences. In the book, Mullis chronicles his romantic relationships, use of LSD, synthesis and self-testing of novel psychoactive substances, belief in 614:(although not its individual workers) in the form of a Nobel Prize and a $ 10,000 Cetus bonus for Mullis and $ 300 million for Cetus when the company sold the patent to Roche Molecular Systems. After 427:. White recalled: "It definitely put me in a tough spot. His behavior was so outrageous that the other scientists thought that the only reason I didn't fire him outright was that he was a friend of mine." 719:", i.e. the tendency of some Nobel laureates to go on to embrace ideas that are scientifically implausible, rejected by most scientific experts, and based mostly on anecdotal or uncorroborated evidence. 412:
at Cetus for seven years, ultimately serving as head of the DNA synthesis lab under White, then the firm's director of molecular and biological research; it was there, in 1983, that Mullis invented the
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listed Mullis as one of several scientists who, after success in their area of research, go on to make unfounded, sometimes bizarre statements in other areas, especially in regard to contradicting the
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A drawback of the technique was that the DNA polymerase in the reaction was destroyed by the high heat used at the start of each replication cycle and had to be replaced. In 1986, Saiki started to use
2133: 2519: 535:. UC Berkeley biologist David Bilder said, "PCR revolutionized everything. It really superpowered molecular biology—which then transformed other fields, even distant ones like ecology and 461:. The venture sought to develop technology using atomic-force microscopy and bar-coded antibodies tagged with heavy metals to create highly multiplexed, parallel immunoassays. 3092: 619:
February 1999, the patent of Hoffman-La Roche (United States Patent No. 4,889,818) was found by the courts to be unenforceable, after Dr. Thomas Kunkel testified in the case
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Kaledin, A.S.; Sliusarenko, A.G.; Gorodetskii, S.I. (1980). "Isolation and properties of DNA polymerase from extreme thermophylic bacteria Thermus aquaticus YT-1".
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Mullis, K.F.; Faloona, F.; Scharf, S.; Saiki, R.; Horn, G.; Erlich, H. (1986). "Specific enzymatic amplification of DNA in vitro: The polymerase chain reaction".
5824: 5799: 3038:"Kary Mullis: Obituaries – Nobel prizewinning biochemist and 'surfer dude' whose LSD-taking lifestyle was considered too lurid even for the OJ Simpson trial" 1757: 694:, names Mullis "among the who's who of AIDS pseudoscientists". Mullis was often cited in the press as a supporter of molecular biologist and AIDS denialist 5819: 3449: 3120: 1416: 706:'s denialist policymaking throughout his tenure as president of South Africa from 1999 to 2008, contributing to as many as 330,000 unnecessary deaths. 5055: 3249: 634:
wrote a book on the history of the PCR method in 1996, in which he discusses whether Mullis "invented" PCR or merely came up with the concept of it.
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Pon, Richard T. (2002). "Chemical Synthesis of Oligonucleotides: From Dream to Automation". In Khudyakov, Yury E.; Fields, Howard A. (eds.).
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In 1983, Mullis was working for Cetus Corporation as a chemist. Mullis recalled that, while driving in the vicinity of his country home in
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Nelkin, Dorothy; Andrews, Lori (September–October 1998). "Homo Economicus: Commercialization of Body Tissue in the Age of Biotechnology".
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Mullis, Kary B.; Pollack, J. R.; Neilands, J. B. (1971). "Structure of schizokinen, An iron-transport compound from Bacillus megaterium".
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Thereafter, Mullis worked intermittently as a consultant for multiple corporations and institutions on nucleic acid chemistry and as an
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Nattrass, Nicoli; Kalichman, Seth C. (2009). "The Politics and Psychology of AIDS Denialism". In Rohleder, Paul; et al. (eds.).
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Kristian, SA; Hwang, JH; Hall, B; Leire, E; Iacomini, J; Old, R; Galili, U; Roberts, C; Mullis, KB; Westby, M; Nizet, V (2015).
3545: 3283: 1998: 1067: 330: 102: 2262:(1971). "Studies on polynucleotides *1, *2XCVI. Repair replication of short synthetic DNA's as catalyzed by DNA polymerases". 449:. In 1992, Mullis founded a business to sell pieces of jewelry containing the amplified DNA of deceased famous people such as 5784: 4964: 4156: 610: 1906: 337:
in 1966, during which time he married his first wife, Richards Haley, and started a business. He earned his PhD in 1973 in
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He founded Altermune LLC in 2011 to pursue new ideas on the immune system. Mullis described the company's product thusly:
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of the American Society of Human Genetics, Preis Biochemische Analytik of the German Society of Clinical Chemistry and
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Other Cetus scientists who were regarded as "top-notch experimentalists", including Randall Saiki, Henry Erlich, and
2804:"A hypothetical disease of the immune system that may bear some relation to the Acquired Immune Deficiency Syndrome" 2536: 1224:
Shampo, M. A.; Kyle, R. A. (2002). "Kary B. Mullis – Nobel Laureate for procedure to replicate DNA".
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as "highly original and significant, virtually dividing biology into the two epochs of before PCR and after PCR."
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for two years. While inventing a UV-sensitive ink at Xytronyx, he became skeptical of the existence of the
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In his 1998 autobiography, Mullis expressed disagreement with the scientific evidence for humans' role in
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for $ 300 million would lead Mullis to condemn White and members of the parallel team as "vultures."
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After resigning from Cetus in 1986, Mullis served as director of molecular biology for Xytronyx, Inc. in
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and wrote about an encounter with a fluorescent, talking raccoon that he suggested might have been an
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His co-workers at Cetus contested the notion that Mullis was solely responsible for the idea of using
562:, Mullis describes how the US Government paid $ 500,000 for Mullis to use this new technology against 393:
secured Mullis's UCSF position and later helped Mullis land a position with the biotechnology company
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has written that the "full potential was not realized" until Mullis's work in 1983, and journalist
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Basterfield, Candice; Lilienfeld, Scott O.; Bowes, Shauna M.; Costello, Thomas H. (May–June 2020).
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bottles, nor the sweet smell of the dawn of the age of PCR could replace Jenny. I was lonesome."
319: 290: 288:. Mullis's unscientific statements about topics outside his area of expertise have been named by 277: 265: 5729: 5691: 1833: 2986: 5725: 5719: 5711: 5604: 5548: 5507: 5503: 5447: 5441: 5261: 4980: 4638: 4606: 4439: 4423: 4279: 4064: 3813: 3601: 3412: 3207: 3073: 3046: 2967: 2966:. Vol. 105, no. 1. Berkeley, California: California Alumni Association. p. 20. 2937: 2885: 2862: 2831: 2823: 2782: 2744: 2663: 2634: 2545: 2510: 2474: 2440: 2409: 2380: 2306: 2279: 2240: 2100: 1966: 1950: 1913: 1883: 1815: 1807: 1765: 1709: 1666: 1639: 1505: 1385: 1281: 1241: 1042: 985: 961: 929: 922: 907: 862: 736: 585: 503: 402: 394: 260: 178: 149: 2680: 5594: 5382: 5356: 5290: 5235: 5231: 4862: 4858: 4786: 4710: 4674: 4622: 4586: 4543: 4431: 4307: 4287: 4263: 4196: 4072: 4056: 4008: 3917: 3765: 3577: 3561: 3494: 3036: 3016: 2929: 2815: 2734: 2602: 2518: 2370: 2362: 2271: 2230: 2222: 2092: 1942: 1873: 1799: 1701: 1326: 1300: 1271: 1233: 1116: 1102: 1029: 953: 899: 854: 825: 495: 351: 201: 5747: 5733: 5701: 5656: 5642: 5614: 5483: 5465: 5433: 5396: 5282: 5225: 5211: 4846: 4838: 4774: 4758: 4694: 4686: 4654: 4539: 4491: 4467: 4383: 4244: 4128: 3973: 3941: 3884: 3821: 3706: 3633: 3609: 3331: 657: 5598: 4566: 1202: 584:
A concept similar to that of PCR had been described before Mullis's work. Nobel laureate
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2010: Honorary degree of Doctor honoris causa in the field of biological sciences from
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in his autobiography. In a Q&A interview published in the September 1994 issue of
715:, Mullis's statements on HIV/AIDS and human-caused climate change are an instance of " 5763: 5739: 5715: 5652: 5622: 5588: 5570: 5531: 5461: 5336: 5278: 4971: 4882: 4878: 4850: 4826: 4790: 4754: 4730: 4714: 4702: 4610: 4582: 4499: 4411: 4315: 4160: 4152: 4096: 4088: 4036: 4016: 3965: 3789: 3781: 3645: 3585: 3484: 3420: 3356: 2275: 882:
Mullis, Kary B. (April 1990). "The Unusual Origin of the Polymerase Chain Reaction".
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Mullis also invented a UV-sensitive plastic that changes color in response to light.
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inspired to fight this particular strep bacterium because it had killed his friend.
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Schoch, Russell (September 1994). "Q&A – A Conversation with Kerry Mullis".
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Youson, Patricia (May 31, 2000). "Acquired Immune Deficiency Syndrome (AIDS)".
677:, despite never having done any scientific research on either subject, leading 5670: 5646: 5413: 5360: 5239: 4678: 4614: 4594: 4519: 4327: 4232: 4180: 4104: 3985: 3981: 3809: 3304: 2803: 2400: 2226: 1092: 941: 758: 435: 369: 285: 236: 4894: 3416: 3378: 3077: 3050: 2971: 2866: 2827: 2667: 2514: 2444: 1954: 1887: 1811: 1769: 1713: 1643: 1389: 1378:"The Nobel Disease: When Intelligence Fails to Protect against Irrationality" 1285: 5513: 5374: 5350: 4299: 3925: 2933: 2302: 2096: 2027: 1670: 1180:, Nobel laureate who has promoted controversial and unverified health claims 997: 795: 766: 536: 532: 431: 326: 281: 2748: 2244: 1970: 1245: 468:'s Advisory Board. In 2014, he was named a distinguished researcher at the 3465: 2941: 2835: 2413: 2283: 2104: 1819: 965: 911: 866: 5151: 1273:"Scientist at Work/Kary Mullis; After the 'Eureka', a Nobelist Drops Out" 559: 528: 2739: 2722: 1803: 1417:"The Man Who Photocopied DNA and Also Saw a Talking Fluorescent Raccoon" 43: 2819: 2384: 1962: 1684:
Mullis, Kary (May 1968). "Cosmological Significance of Time Reversal".
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Kalichman, Seth (2009). "Appendix B: About the HIV/AIDS Denialists".
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Life on the Edge: Amazing Creatures Thriving in Extreme Environments
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Denying AIDS: Conspiracy Theories, Pseudoscience, and Human Tragedy
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Mullis, Kary (1968). "Cosmological Significance of Time Reversal".
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Mullis also questioned the scientific validity of the link between
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throughout his graduate studies, specializing in the synthesis of
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United States District Court, N.D. California. (July 26, 2001).
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His doctoral dissertation was on the structure of the bacterial
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HIV/AIDS in South Africa 25 Years On: Psychosocial Perspectives
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2004: Honorary degree in Pharmaceutical Biotechnology from the
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Nobel Prize Winner Among Rondal H. Brown Award Recipients
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Cosgrove). Mullis died on August 7, 2019, at his home in
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Hyle: International Journal for Philosophy of Chemistry
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Salem Press Biographical Encyclopedia: Kary B. Mullis
992:) gives his account of the commercial development of 239:. In recognition of his role in the invention of the 3148:. American Society of Human Genetics. Archived from 1054:
1994: Honorary degree of Doctor of Science from the
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PCR (Polymerase Chain Reaction) and other inventions
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in the same year. PCR became a central technique in
5680: 5541: 5406: 5271: 5190: 5054: 5029: 5004: 4979: 4959: 4934: 4553: 4254: 3995: 3756: 3536: 3355:(in Italian). University of Bologna. Archived from 2258:Kleppe, K.; Ohtsuka, E.; Kleppe, R.; Molineux, I.; 1419:. McGill University, Office for Science and Society 847:
Cold Spring Harbor Symposia on Quantitative Biology
457:. In the same year, he also founded Atomic Tags in 216: 200: 184: 174: 137: 122: 98: 79: 53: 34: 2774: 2535: 2466: 2149: 2147: 1905: 1629: 1371: 1369: 1367: 1365: 761:. For example, he said that he had witnessed the " 2578:. Wellington, New Zealand: Science Media Centre. 1495: 1493: 1491: 1163:List of National Inventors Hall of Fame inductees 3303:, Invent.org, December 28, 1944, archived from 2496: 2494: 2492: 2490: 1631:"Is Kary Mullis God? (Or Just the Big Kahuna?)" 1158:History of the polymerase chain reaction method 551: 3197: 3195: 3193: 3191: 3189: 2768: 2766: 2565: 2563: 2561: 1620: 1618: 1616: 1614: 682:that AIDS is an arbitrary diagnosis used when 470:Children's Hospital Oakland Research Institute 360:committee to reconsider its initial decision. 5167: 4910: 3510: 2473:. University of Chicago Press. pp. 4–5. 1899: 1897: 1638:. Vol. 122, no. 1. pp. 68–75. 1612: 1610: 1608: 1606: 1604: 1602: 1600: 1598: 1596: 1594: 8: 3330:, USA: PTO, October 13, 1998, archived from 2349:Chien, A.; Edgar, D.B.; Trela, J.M. (1976). 2022: 2020: 1751: 1410: 1408: 1406: 1038:1992: California Scientist of the Year Award 2654:Nattrass, Nicoli (September–October 2007). 1749: 1747: 1745: 1743: 1741: 1739: 1737: 1735: 1733: 1731: 1438: 1436: 1434: 1265: 1263: 1261: 1259: 1257: 1255: 1197: 1195: 5174: 5160: 5152: 4917: 4903: 4895: 3517: 3503: 3495: 3469: 3441: 3172:"Award Winners 1970 – 2017" 2781:(1st ed.). New York: Pantheon Books. 1153:COVID-19 misinformation § PCR testing 1070:, Ronald H. Brown American Innovator Award 191:Schizokinen: structure and synthetic work 42: 31: 2738: 2374: 2234: 1663:Schizokinen: Structure and Synthetic Work 1320: 1318: 1316: 274:downplayed humans' role in climate change 3206:. New York: Facts On File. p. 163. 2299:Artificial DNA: Methods and Applications 1882:. Technology Quarterly. March 13, 2004. 5835:UC Berkeley College of Chemistry alumni 3228:"The John Scott Award Recipients: 2007" 3045:. London. October 9, 2019. p. 53. 1350:Arnaud, Celia Henry (August 21, 2019). 1325:McClain, Dylan Loeb (August 15, 2019). 1191: 621:Hoffman-La Roche v. Promega Corporation 382:University of California, San Francisco 3252:. Robert-Koch-Stiftung. Archived from 3146:"Past Recipients, William Allan Award" 3064:Thompson, M. Dion (October 13, 1998). 3015:Golden, Frederic (December 13, 2000). 2001:. USA science festival. Archived from 1976: 1912:. New York: Basic Books. p. 103. 1650:from the original on February 6, 2020. 668:scientific consensus on climate change 5840:Writers from Columbia, South Carolina 3405:"Kary Mullis, the great gene machine" 2723:"AIDS denialists back on the upswing" 2582:from the original on January 20, 2021 2157:A next-gen cure for killer infections 1856: 1854: 1339:from the original on January 3, 2022. 1270:Wade, Nicholas (September 15, 1998). 1004:in the form of a fluorescent raccoon. 702:, Mullis's HIV skepticism influenced 7: 2693:Kalichman, Seth (November 3, 2009). 2601:Johnson, George (October 28, 2007). 2469:Making PCR: A Story of Biotechnology 2140:(Press release). September 22, 2011. 1661:Mullis, Kary Banks (December 1973). 1168:List of Nobel laureates in Chemistry 1024:1991: National Biotechnology Award, 638:Views on HIV/AIDS and climate change 580:History of polymerase chain reaction 490:History of polymerase chain reaction 466:USA Science and Engineering Festival 243:(PCR) technique, he shared the 1993 5825:American psychedelic drug advocates 5800:Deaths from pneumonia in California 2633:. New York: Springer. p. 124. 2501:Carlson, Peter (November 3, 1998). 2189:University of California, San Diego 2122:. Salem Press, a division of EBSCO. 1526:"The Nobel Prize in Chemistry 1993" 1471:"The Nobel Prize in Chemistry 1993" 1415:Jarry, Jonathan (August 15, 2019). 374:University of Kansas Medical Center 325:He earned a Bachelor of Science in 278:doubt that HIV is the cause of AIDS 5820:People from Lenoir, North Carolina 3403:Liversidge, Anthony (April 1992). 2985:Harrison, Ann (January 16, 2006). 1299:Pineda, Dorany (August 13, 2019). 574:Accreditation of the PCR technique 343:University of California, Berkeley 112:University of California, Berkeley 25: 3450:"Patent Portfolio of Kary Mullis" 3353:"Laurea ad honorem a Kary Mullis" 2570:Winter, David (October 8, 2011). 2183:Buschman, Heather (May 6, 2015). 1028:, R&D Scientist of the Year, 904:10.1038/scientificamerican0490-56 757:Mullis expressed interest in the 3747: 3091:Clark, Debbie (August 9, 2019). 2604:"Bright Scientists, Dim Notions" 1504:. Greenwood Press. p. 184. 1500:Shmaefsky, Brian Robert (2006). 1137: 1123: 1109: 1095: 1060:1994: Golden Plate Award of the 1047:1993: Nobel Prize in Chemistry, 690:, AIDS researcher and author of 686:are found in a patient's blood. 5601:/ John Frederick Grassle (2013) 3284:American Academy of Achievement 2777:Dancing Naked in the Mind Field 2695:"How to spot an AIDS denialist" 2542:Dancing Naked in the Mind Field 2367:10.1128/jb.127.3.1550-1557.1976 1356:Chemical & Engineering News 1068:National Inventors Hall of Fame 1062:American Academy of Achievement 982:Dancing Naked in the Mind Field 401:. Despite little experience in 331:Georgia Institute of Technology 103:Georgia Institute of Technology 27:American biochemist (1944–2019) 5830:Scientists from North Carolina 2987:"LSD: The Geek's Wonder Drug?" 2429:"Ethnography of a Nobel Prize" 2154:Mullis, Kary (February 2009). 1756:McDonald, Coby (Winter 2019). 1569:Mullis, Kary (February 2002). 1203:"Laureates of the Japan Prize" 1: 5311:Ernest John Christopher Polge 3489:, Nobel Prize committee, 2005 3018:"The Worst And The Brightest" 2721:Basu, Paroma (June 1, 2005). 1983:: CS1 maint: date and year ( 1445:"Kary B. Mullis Biographical" 919:The Polymerase Chain Reaction 623:on behalf of the defendants ( 5815:Nobel laureates in Chemistry 2662:. Vol. 31, no. 5. 2656:"AIDS Denialism vs. Science" 2276:10.1016/0022-2836(71)90469-4 2264:Journal of Molecular Biology 1384:. Vol. 44, no. 3. 1352:"Kary Mullis dies at age 74" 1056:University of South Carolina 1016:William Allan Memorial Award 980:Mullis's 1998 autobiography 753:Interest in the supernatural 605:in PCR. However, biochemist 595:Journal of Molecular Biology 280:, and professed a belief in 1572:Play! Experiment! Discover! 859:10.1101/sqb.1986.051.01.032 464:Mullis was a member of the 5856: 3232:garfield.library.upenn.edu 1935:The Hastings Center Report 1764:. Cal Alumni Association. 641: 577: 483: 5327:William Hayward Pickering 5202:Ephraim Katchalski-Katzir 5079: 3745: 3202:Newton, David E. (2007). 2907:"The Duesberg phenomenon" 2427:Bilsker, Richard (1998). 2227:10.1007/s00109-015-1280-4 1451:. Nobel Prize Outreach AB 1173:Nobel Prize controversies 1000:and an encounter with an 792:Newport Beach, California 415:polymerase chain reaction 241:polymerase chain reaction 212: 167: 128:polymerase chain reaction 91:Newport Beach, California 41: 5790:American Nobel laureates 5020:Joseph Hooton Taylor Jr. 4995:Frederik Willem de Klerk 4671:Venkatraman Ramakrishnan 3950:Wendell Meredith Stanley 3530:Nobel Prize in Chemistry 2802:Mullis, Kary B. (1995). 1443:Mullis, Kary B. (n.d.). 1205:. Japan Prize Foundation 1066:1998: Inducted into the 1051:, Thomas A. Edison Award 940:Mullis, Kary B. (1995). 794:, from complications of 378:pharmaceutical chemistry 316:Columbia, South Carolina 302:Early life and education 245:Nobel Prize in Chemistry 155:Nobel Prize in Chemistry 5468:/ Keith J. Sainsbury / 3003:specific DNA sequences. 2934:10.1126/science.7992043 2859:The Washington Informer 2164:(video with transcript) 2097:10.1126/science.2999980 1904:Gross, Michael (2001). 1875:"DNA's detective story" 1579:(video with transcript) 1226:Mayo Clinic Proceedings 541:Roche Molecular Systems 502:. Neither Fred, empty 5639:Emmanuelle Charpentier 5258:Frank Sherwood Rowland 5085:Nobel Prize recipients 5031:Physiology or Medicine 4835:Emmanuelle Charpentier 4823:M. Stanley Whittingham 3794:Hans von Euler-Chelpin 2523:on September 23, 2021. 2465:Rabinow, Paul (1996). 1032:of the City Trusts of 771:extraterrestrial alien 556: 519:Thermophilus aquaticus 399:Emeryville, California 308:Lenoir, North Carolina 72:Lenoir, North Carolina 5785:American libertarians 4205:Christian B. Anfinsen 3845:FrĂ©dĂ©ric Joliot-Curie 2773:Mullis, Kary (1998). 2683:, semanticscholar.org 2534:Mullis, Kary (1998). 1075:University of Bologna 802:Selected publications 729:clandestine chemistry 670:and ozone depletion. 648:Climate change denial 405:, Mullis worked as a 5780:American biochemists 5744:John Michael Wallace 4867:Karl Barry Sharpless 4364:Dudley R. Herschbach 4189:Luis Federico Leloir 3460:on January 10, 2013. 3423:on January 21, 2001. 3381:. Masaryk University 3359:on February 27, 2021 3334:on February 20, 2009 3297:"Inventor Profile", 3098:The Post and Courier 2301:. Boca Raton, Fla.: 2118:Vigue, C.L. (2021). 1145:United States portal 763:non-substantial form 723:Use of hallucinogens 459:La Jolla, California 318:, where he attended 312:Blue Ridge Mountains 251:and was awarded the 5810:HIV/AIDS denialists 5805:Georgia Tech alumni 5728:/ Kazuo Hagimoto / 5567:Tadamitsu Kishimoto 5297:Jacques-Louis Lions 4859:Carolyn R. Bertozzi 4771:Jean-Pierre Sauvage 4508:Jens Christian Skou 4476:F. Sherwood Rowland 4388:Charles J. Pedersen 4352:Herbert A. Hauptman 4045:Vincent du Vigneaud 3662:Richard Willstätter 3546:Jacobus van 't Hoff 3379:"Kary Banks Mullis" 3280:www.achievement.org 3256:on February 1, 2019 3250:"Robert Koch Award" 2926:1994Sci...266.1642C 2920:(5191): 1642–1644. 2905:Cohen, Jon (1994). 2740:10.1038/nm0605-581b 2572:"The Nobel disease" 2507:The Washington Post 2089:1985Sci...230.1350S 2083:(4732): 1350–1354. 1804:10.1021/bi00802a010 1762:California Magazine 1698:1968Natur.218..663M 1280:. pp. F1, F5. 1020:Boehringer Mannheim 896:1990SciAm.262d..56M 884:Scientific American 822:1968Natur.218..663M 700:California Magazine 630:The anthropologist 625:Promega Corporation 474:Oakland, California 424:California Magazine 306:Mullis was born in 294:as an instance of " 143:William Allan Award 5706:Robert A. Weinberg 5688:Robert G. Gallager 5633:Steven D. Tanksley 5619:Theodore Friedmann 5522:Victor A. McKusick 5480:Masatoshi Takeichi 5428:Timothy R. Parsons 5424:John B. Goodenough 5418:Kimishige Ishizaka 5393:Jack L. Strominger 5389:W. Wesley Peterson 5369:Hiroyuki Yoshikawa 5365:Joseph Engelberger 5341:Edward F. Knipling 5039:Richard J. Roberts 5014:Russell Alan Hulse 4819:John B. Goodenough 4747:William E. Moerner 4627:Richard R. Schrock 4599:Roderick MacKinnon 4571:K. Barry Sharpless 4396:Johann Deisenhofer 4225:Geoffrey Wilkinson 4221:Ernst Otto Fischer 4145:Robert S. Mulliken 4081:Jaroslav HeyrovskĂ˝ 4029:Hermann Staudinger 3849:Irène Joliot-Curie 3468:on Nobelprize.org 3204:Forensic Chemistry 2964:California Monthly 2820:10.1007/bf01435010 2660:Skeptical Inquirer 2609:The New York Times 2537:"I am a Capricorn" 1382:Skeptical Inquirer 1333:The New York Times 1278:The New York Times 1082:Masaryk University 958:10.1007/BF01435010 742:California Monthly 712:Skeptical Inquirer 663:The New York Times 644:HIV/AIDS denialism 345:(UC Berkeley), in 320:Dreher High School 291:Skeptical Inquirer 266:The New York Times 5757: 5756: 5726:Masataka Nakazawa 5720:Christopher Field 5605:Yasuharu Suematsu 5549:Shun-ichi Iwasaki 5508:Peter Shaw Ashton 5448:Benoit Mandelbrot 5442:Andrzej Tarkowski 5262:Elias James Corey 5149: 5148: 5056:Economic Sciences 4892: 4891: 4875:Moungi G. Bawendi 4795:Richard Henderson 4639:Roger D. Kornberg 4607:Aaron Ciechanover 4440:Rudolph A. Marcus 4344:Robert Merrifield 4280:Peter D. Mitchell 4053:Cyril Hinshelwood 3814:Friedrich Bergius 3738:Richard Zsigmondy 3654:Theodore Richards 3602:Ernest Rutherford 3454:DirectoryInventor 3213:978-1-4381-0976-3 3152:on August 4, 2019 3101:. Charleston, S.C 3070:The Baltimore Sun 2951:on June 15, 2006. 2891:978-0-3877-9476-1 2788:978-0-679-44255-4 2640:978-1-4419-0306-8 2551:978-0-679-77400-6 2312:978-1-4200-4016-6 2187:(Press release). 2005:on April 21, 2010 1919:978-0-7382-0445-1 1798:(26): 4894–4898. 1692:(5142): 663–664. 1511:978-0-313-33528-0 1502:Biotechnology 101 1307:Los Angeles Times 1276:. Science Times. 1043:Robert Koch Prize 1009:Awards and honors 990:978-0-679-77400-6 934:978-0-8176-3750-7 816:(5142): 663–664. 727:Mullis practiced 586:H. Gobind Khorana 417:(PCR) procedure. 403:molecular biology 395:Cetus Corporation 261:molecular biology 233:Kary Banks Mullis 230: 229: 179:Molecular biology 169:Scientific career 150:Robert Koch Prize 68:December 28, 1944 58:Kary Banks Mullis 18:Kary Banks Mullis 16:(Redirected from 5847: 5795:Biotechnologists 5595:C. Grant Willson 5383:Marc Van Montagu 5357:Takashi Sugimura 5291:Xavier Le Pichon 5236:Donald Henderson 5232:Georges Vendryes 5176: 5169: 5162: 5153: 5087: 5045:Phillip A. Sharp 5041:(United Kingdom) 4919: 4912: 4905: 4896: 4885: 4883:Alexei I. Ekimov 4869: 4863:Morten P. Meldal 4853: 4841: 4829: 4813: 4797: 4787:Jacques Dubochet 4781: 4765: 4749: 4733: 4717: 4711:Robert Lefkowitz 4705: 4697: 4681: 4675:Thomas A. Steitz 4665: 4649: 4641: 4633: 4623:Robert H. Grubbs 4617: 4601: 4589: 4573: 4546: 4544:Hideki Shirakawa 4530: 4522: 4510: 4494: 4478: 4462: 4454: 4442: 4434: 4432:Richard R. 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Evans 5734:Karl Deisseroth 5730:Gero Miesenböck 5702:Bert Vogelstein 5698:Martin A. Green 5676: 5657:Max Dale Cooper 5643:Jennifer Doudna 5615:Yutaka Takahasi 5537: 5484:Erkki Ruoslahti 5466:Akira Fujishima 5434:Tim Berners-Lee 5402: 5397:Don Craig Wiley 5283:W. Jason Morgan 5267: 5226:Theodore Maiman 5212:Willem J. Kolff 5186: 5180: 5150: 5145: 5083: 5075: 5072:(United States) 5066:(United States) 5050: 5047:(United States) 5025: 5022:(United States) 5016:(United States) 5000: 4975: 4974:(United States) 4955: 4946:(United States) 4930: 4923: 4893: 4888: 4872: 4856: 4847:David MacMillan 4844: 4839:Jennifer Doudna 4832: 4816: 4800: 4784: 4775:Fraser Stoddart 4768: 4759:Paul L. Modrich 4752: 4736: 4720: 4708: 4700: 4695:Ei-ichi Negishi 4687:Richard F. Heck 4684: 4668: 4655:Osamu Shimomura 4652: 4644: 4636: 4620: 4604: 4592: 4576: 4563:William Knowles 4560: 4549: 4540:Alan MacDiarmid 4533: 4525: 4513: 4497: 4492:Richard Smalley 4481: 4468:Paul J. 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According to 658:ozone depletion 650: 640: 582: 576: 492: 484:Main articles: 482: 390: 304: 263:, described by 220: 194: 158: 153: 148: 145: 141: 130: 110: 99:Alma mater 94: 88: 84: 75: 69: 63: 61: 60: 59: 49: 37: 28: 23: 22: 15: 12: 11: 5: 5853: 5851: 5843: 5842: 5837: 5832: 5827: 5822: 5817: 5812: 5807: 5802: 5797: 5792: 5787: 5782: 5777: 5772: 5762: 5761: 5755: 5754: 5752: 5751: 5737: 5723: 5712:Katalin KarikĂł 5709: 5695: 5684: 5682: 5678: 5677: 5675: 5674: 5667:Yoshio Okamoto 5664: 5661:Jacques Miller 5650: 5636: 5626: 5612: 5609:C. David Allis 5602: 5592: 5585:Nicholas Lydon 5574: 5563:Dennis Ritchie 5556: 5553:Peter Vitousek 5545: 5543: 5539: 5538: 5536: 5535: 5528:Dennis Meadows 5525: 5518:Robert E. Kahn 5511: 5504:Peter GrĂĽnberg 5497: 5487: 5473: 5470:John H. Lawton 5459: 5452:James A. Yorke 5445: 5431: 5421: 5410: 5408: 5404: 5403: 5401: 5400: 5386: 5372: 5354: 5347:Charles K. Kao 5344: 5334: 5331:Arvid Carlsson 5324: 5321:Kary B. Mullis 5314: 5304: 5294: 5275: 5273: 5269: 5268: 5266: 5265: 5255: 5248:Luc Montagnier 5229: 5218:Henry Beachell 5215: 5208:David Turnbull 5205: 5198:John R. Pierce 5194: 5192: 5188: 5187: 5181: 5179: 5178: 5171: 5164: 5156: 5147: 5146: 5144: 5143: 5138: 5133: 5128: 5123: 5118: 5113: 5108: 5103: 5098: 5093: 5088: 5080: 5077: 5076: 5074: 5073: 5070:Douglass North 5067: 5060: 5058: 5052: 5051: 5049: 5048: 5042: 5035: 5033: 5027: 5026: 5024: 5023: 5017: 5010: 5008: 5002: 5001: 4999: 4998: 4997:(South Africa) 4992: 4991:(South Africa) 4989:Nelson Mandela 4985: 4983: 4977: 4976: 4970: 4968: 4957: 4956: 4954: 4953: 4947: 4944:Kary B. Mullis 4940: 4938: 4932: 4931: 4924: 4922: 4921: 4914: 4907: 4899: 4890: 4889: 4887: 4886: 4870: 4854: 4842: 4830: 4814: 4807:Gregory Winter 4803:Frances Arnold 4798: 4782: 4766: 4750: 4734: 4727:Michael Levitt 4723:Martin Karplus 4718: 4706: 4698: 4682: 4666: 4663:Roger Y. Tsien 4659:Martin Chalfie 4650: 4642: 4634: 4618: 4602: 4590: 4574: 4557: 4555: 4551: 4550: 4548: 4547: 4536:Alan J. Heeger 4531: 4523: 4511: 4504:John E. Walker 4495: 4479: 4463: 4455: 4443: 4435: 4427: 4419: 4407: 4404:Hartmut Michel 4391: 4380:Donald J. Cram 4375: 4359: 4347: 4339: 4331: 4323: 4320:Roald Hoffmann 4311: 4304:Walter Gilbert 4295: 4283: 4275: 4272:Ilya Prigogine 4267: 4258: 4256: 4252: 4251: 4249: 4248: 4241:John Cornforth 4236: 4228: 4216: 4209:Stanford Moore 4200: 4192: 4184: 4172: 4164: 4157:Ronald Norrish 4148: 4140: 4132: 4124: 4112: 4100: 4092: 4084: 4076: 4068: 4065:Alexander Todd 4060: 4048: 4040: 4032: 4024: 4012: 4005:Edwin McMillan 3999: 3997: 3993: 3992: 3990: 3989: 3977: 3969: 3961: 3953: 3937: 3929: 3921: 3913: 3906: 3899: 3892: 3880: 3872: 3865:Norman Haworth 3860: 3852: 3840: 3832: 3825: 3817: 3805: 3797: 3785: 3777: 3769: 3760: 3758: 3754: 3753: 3746: 3744: 3742: 3741: 3733: 3726: 3718: 3710: 3702: 3699:Walther Nernst 3694: 3687: 3679: 3672: 3665: 3657: 3649: 3641: 3629: 3621: 3613: 3605: 3597: 3594:Eduard Buchner 3589: 3581: 3573: 3570:William Ramsay 3565: 3557: 3549: 3540: 3538: 3534: 3533: 3524: 3522: 3521: 3514: 3507: 3499: 3493: 3492: 3479: 3476: 3475: 3474: 3466:Kary B. Mullis 3463: 3446: 3430: 3429:External links 3427: 3426: 3425: 3398: 3395: 3393: 3392: 3370: 3344: 3317: 3289: 3267: 3241: 3219: 3212: 3185: 3163: 3137: 3112: 3083: 3072:. p. 1E. 3056: 3028: 3007: 2977: 2954: 2897: 2890: 2872: 2849: 2794: 2787: 2762: 2713: 2685: 2673: 2646: 2639: 2621: 2593: 2557: 2550: 2526: 2509:. p. D1. 2486: 2479: 2457: 2439:(2): 167–169. 2419: 2408:(4): 644–651. 2390: 2341: 2318: 2311: 2305:. p. 20. 2289: 2270:(2): 341–361. 2260:Khorana, H. G. 2250: 2201: 2175: 2143: 2125: 2110: 2066: 2044: 2032:Karymullis.com 2016: 1990: 1925: 1918: 1893: 1865: 1863:karymullis.com 1850: 1825: 1782: 1727: 1676: 1653: 1590: 1561: 1556:NobelPrize.org 1550:Mullis, Kary. 1542: 1530:NobelPrize.org 1517: 1510: 1487: 1475:NobelPrize.org 1462: 1449:NobelPrize.org 1430: 1402: 1361: 1342: 1312: 1291: 1251: 1216: 1190: 1188: 1185: 1184: 1183: 1182: 1181: 1178:Luc Montagnier 1170: 1165: 1160: 1155: 1149: 1148: 1134: 1131:History portal 1120: 1106: 1090: 1087: 1086: 1085: 1078: 1071: 1064: 1058: 1052: 1045: 1039: 1036: 1026:Gairdner Award 1022: 1010: 1007: 1006: 1005: 978: 937: 916: 879: 842: 803: 800: 778: 775: 754: 751: 747:Albert Hofmann 724: 721: 696:Peter Duesberg 688:Seth Kalichman 684:HIV antibodies 679:Seth Kalichman 654:climate change 639: 636: 607:Richard T. Pon 603:Taq polymerase 575: 572: 524:DNA polymerase 511:Norman Arnheim 486:Taq Polymerase 481: 478: 455:Marilyn Monroe 443:expert witness 389: 386: 347:J. B. Neilands 303: 300: 228: 227: 218: 214: 213: 210: 209: 207:J. B. Neilands 204: 198: 197: 188: 182: 181: 176: 172: 171: 165: 164: 139: 135: 134: 124: 123:Known for 120: 119: 100: 96: 95: 89: 87:(aged 74) 83:August 7, 2019 81: 77: 76: 70: 57: 55: 51: 50: 48:Mullis in 2006 47: 39: 38: 35: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 5852: 5841: 5838: 5836: 5833: 5831: 5828: 5826: 5823: 5821: 5818: 5816: 5813: 5811: 5808: 5806: 5803: 5801: 5798: 5796: 5793: 5791: 5788: 5786: 5783: 5781: 5778: 5776: 5773: 5771: 5768: 5767: 5765: 5749: 5745: 5741: 5740:Brian Hoskins 5738: 5735: 5731: 5727: 5724: 5721: 5717: 5716:Drew Weissman 5713: 5710: 5707: 5703: 5699: 5696: 5693: 5689: 5686: 5685: 5683: 5679: 5672: 5668: 5665: 5662: 5658: 5654: 5653:Akira Yoshino 5651: 5648: 5644: 5640: 5637: 5634: 5630: 5627: 5624: 5623:Alain Fischer 5620: 5616: 5613: 5610: 5606: 5603: 5600: 5596: 5593: 5590: 5589:Masato Sagawa 5586: 5582: 5578: 5575: 5572: 5571:Toshio Hirano 5568: 5564: 5560: 5557: 5554: 5550: 5547: 5546: 5544: 5540: 5533: 5532:David E. Kuhl 5529: 5526: 5523: 5519: 5515: 5512: 5509: 5505: 5501: 5498: 5495: 5491: 5490:John Houghton 5488: 5485: 5481: 5477: 5474: 5471: 5467: 5463: 5462:Kenichi Honda 5460: 5457: 5453: 5449: 5446: 5443: 5439: 5435: 5432: 5429: 5425: 5422: 5419: 5415: 5412: 5411: 5409: 5405: 5398: 5394: 5390: 5387: 5384: 5380: 5376: 5373: 5370: 5366: 5362: 5358: 5355: 5352: 5348: 5345: 5342: 5338: 5337:Nick Holonyak 5335: 5332: 5328: 5325: 5322: 5318: 5315: 5312: 5308: 5305: 5302: 5298: 5295: 5292: 5288: 5284: 5280: 5279:Marvin Minsky 5277: 5276: 5274: 5270: 5263: 5259: 5256: 5253: 5249: 5245: 5241: 5237: 5233: 5230: 5227: 5223: 5219: 5216: 5213: 5209: 5206: 5203: 5199: 5196: 5195: 5193: 5189: 5184: 5177: 5172: 5170: 5165: 5163: 5158: 5157: 5154: 5142: 5139: 5137: 5134: 5132: 5129: 5127: 5124: 5122: 5119: 5117: 5114: 5112: 5109: 5107: 5104: 5102: 5099: 5097: 5094: 5092: 5089: 5086: 5082: 5081: 5078: 5071: 5068: 5065: 5062: 5061: 5059: 5057: 5053: 5046: 5043: 5040: 5037: 5036: 5034: 5032: 5028: 5021: 5018: 5015: 5012: 5011: 5009: 5007: 5003: 4996: 4993: 4990: 4987: 4986: 4984: 4982: 4978: 4973: 4972:Toni Morrison 4969: 4966: 4962: 4958: 4951: 4950:Michael Smith 4948: 4945: 4942: 4941: 4939: 4937: 4933: 4928: 4920: 4915: 4913: 4908: 4906: 4901: 4900: 4897: 4884: 4880: 4879:Louis E. Brus 4876: 4871: 4868: 4864: 4860: 4855: 4852: 4851:Benjamin List 4848: 4843: 4840: 4836: 4831: 4828: 4827:Akira Yoshino 4824: 4820: 4815: 4812: 4808: 4804: 4799: 4796: 4792: 4791:Joachim Frank 4788: 4783: 4780: 4776: 4772: 4767: 4764: 4760: 4756: 4755:Tomas Lindahl 4751: 4748: 4744: 4740: 4735: 4732: 4731:Arieh Warshel 4728: 4724: 4719: 4716: 4715:Brian Kobilka 4712: 4707: 4704: 4703:Dan Shechtman 4699: 4696: 4692: 4688: 4683: 4680: 4679:Ada E. Yonath 4676: 4672: 4667: 4664: 4660: 4656: 4651: 4648: 4643: 4640: 4635: 4632: 4628: 4624: 4619: 4616: 4612: 4611:Avram Hershko 4608: 4603: 4600: 4596: 4591: 4588: 4587:Kurt WĂĽthrich 4584: 4583:Koichi Tanaka 4580: 4575: 4572: 4568: 4564: 4559: 4558: 4556: 4552: 4545: 4541: 4537: 4532: 4529: 4524: 4521: 4517: 4512: 4509: 4505: 4501: 4500:Paul D. Boyer 4496: 4493: 4489: 4485: 4480: 4477: 4473: 4469: 4464: 4461: 4456: 4453: 4452:Michael Smith 4449: 4444: 4441: 4436: 4433: 4428: 4425: 4420: 4417: 4413: 4412:Sidney Altman 4408: 4405: 4401: 4397: 4392: 4389: 4385: 4381: 4376: 4373: 4369: 4365: 4360: 4357: 4353: 4348: 4345: 4340: 4337: 4332: 4329: 4324: 4321: 4317: 4316:Kenichi Fukui 4312: 4309: 4305: 4301: 4296: 4293: 4289: 4284: 4281: 4276: 4273: 4268: 4265: 4260: 4259: 4257: 4253: 4246: 4242: 4237: 4234: 4229: 4226: 4222: 4217: 4214: 4213:William Stein 4210: 4206: 4201: 4198: 4193: 4190: 4185: 4182: 4178: 4173: 4170: 4165: 4162: 4161:George Porter 4158: 4154: 4153:Manfred Eigen 4149: 4146: 4141: 4138: 4133: 4130: 4125: 4122: 4118: 4113: 4110: 4106: 4101: 4098: 4097:Melvin Calvin 4093: 4090: 4089:Willard Libby 4085: 4082: 4077: 4074: 4069: 4066: 4061: 4058: 4054: 4049: 4046: 4041: 4038: 4037:Linus Pauling 4033: 4030: 4025: 4022: 4021:Richard Synge 4018: 4017:Archer Martin 4013: 4010: 4006: 4001: 4000: 3998: 3994: 3987: 3983: 3978: 3975: 3970: 3967: 3966:Arne Tiselius 3962: 3959: 3954: 3951: 3947: 3946:John Northrop 3943: 3938: 3935: 3930: 3927: 3922: 3919: 3914: 3907: 3900: 3893: 3890: 3886: 3881: 3878: 3873: 3870: 3866: 3861: 3858: 3853: 3850: 3846: 3841: 3838: 3833: 3826: 3823: 3818: 3815: 3811: 3806: 3803: 3798: 3795: 3791: 3790:Arthur Harden 3786: 3783: 3782:Adolf Windaus 3778: 3775: 3770: 3767: 3762: 3761: 3759: 3755: 3739: 3734: 3727: 3724: 3719: 3716: 3715:Francis Aston 3711: 3708: 3703: 3700: 3695: 3688: 3685: 3680: 3673: 3666: 3663: 3658: 3655: 3650: 3647: 3646:Alfred Werner 3642: 3639: 3638:Paul Sabatier 3635: 3630: 3627: 3622: 3619: 3614: 3611: 3606: 3603: 3598: 3595: 3590: 3587: 3586:Henri Moissan 3582: 3579: 3574: 3571: 3566: 3563: 3558: 3555: 3550: 3547: 3542: 3541: 3539: 3535: 3531: 3527: 3520: 3515: 3513: 3508: 3506: 3501: 3500: 3497: 3488: 3487: 3482: 3481: 3477: 3472: 3467: 3464: 3459: 3455: 3451: 3447: 3444: 3438: 3433: 3432: 3428: 3422: 3418: 3414: 3410: 3406: 3401: 3400: 3396: 3380: 3374: 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1805: 1801: 1797: 1793: 1786: 1783: 1771: 1767: 1763: 1759: 1752: 1750: 1748: 1746: 1744: 1742: 1740: 1738: 1736: 1734: 1732: 1728: 1723: 1719: 1715: 1711: 1707: 1703: 1699: 1695: 1691: 1687: 1680: 1677: 1672: 1668: 1664: 1657: 1654: 1649: 1645: 1641: 1637: 1632: 1628:(July 1994). 1627: 1621: 1619: 1617: 1615: 1613: 1611: 1609: 1607: 1605: 1603: 1601: 1599: 1597: 1595: 1591: 1578: 1574: 1573: 1565: 1562: 1557: 1553: 1546: 1543: 1531: 1527: 1521: 1518: 1513: 1507: 1503: 1496: 1494: 1492: 1488: 1476: 1472: 1466: 1463: 1450: 1446: 1439: 1437: 1435: 1431: 1418: 1411: 1409: 1407: 1403: 1391: 1387: 1383: 1379: 1372: 1370: 1368: 1366: 1362: 1357: 1353: 1346: 1343: 1338: 1334: 1329: 1321: 1319: 1317: 1313: 1308: 1303: 1295: 1292: 1287: 1283: 1279: 1274: 1266: 1264: 1262: 1260: 1258: 1256: 1252: 1247: 1243: 1239: 1235: 1231: 1227: 1220: 1217: 1204: 1198: 1196: 1192: 1186: 1179: 1176: 1175: 1174: 1171: 1169: 1166: 1164: 1161: 1159: 1156: 1154: 1151: 1150: 1146: 1135: 1132: 1121: 1118: 1107: 1104: 1093: 1088: 1083: 1079: 1076: 1072: 1069: 1065: 1063: 1059: 1057: 1053: 1050: 1046: 1044: 1040: 1037: 1035: 1031: 1027: 1023: 1021: 1017: 1013: 1012: 1008: 1003: 999: 995: 991: 987: 983: 979: 975: 971: 967: 963: 959: 955: 951: 947: 943: 938: 935: 931: 928: 927:0-8176-3750-8 924: 920: 917: 913: 909: 905: 901: 897: 893: 889: 885: 880: 876: 872: 868: 864: 860: 856: 852: 848: 843: 839: 835: 831: 827: 823: 819: 815: 811: 806: 805: 801: 799: 797: 793: 789: 784: 781:Mullis was a 777:Personal life 776: 774: 772: 768: 764: 760: 752: 750: 748: 744: 743: 738: 734: 730: 722: 720: 718: 717:Nobel disease 714: 713: 709:According to 707: 705: 701: 697: 693: 689: 685: 680: 676: 671: 669: 665: 664: 659: 655: 649: 645: 637: 635: 633: 628: 626: 622: 617: 612: 611:Michael Gross 608: 604: 599: 597: 596: 591: 587: 581: 573: 571: 567: 565: 561: 555: 550: 547: 544: 542: 538: 534: 530: 525: 521: 520: 514: 512: 507: 505: 501: 497: 491: 487: 479: 477: 475: 471: 467: 462: 460: 456: 452: 451:Elvis Presley 448: 447:DNA profiling 444: 439: 437: 433: 428: 426: 425: 418: 416: 411: 408: 404: 400: 396: 387: 385: 384:(1977–1979). 383: 379: 375: 371: 366: 361: 358: 354: 353: 348: 344: 340: 336: 332: 328: 323: 321: 317: 313: 309: 301: 299: 297: 296:Nobel disease 293: 292: 287: 283: 279: 275: 270: 268: 267: 262: 258: 254: 250: 249:Michael Smith 246: 242: 238: 234: 225: 219: 215: 211: 208: 205: 203: 199: 192: 189: 187: 183: 180: 177: 173: 170: 166: 161: 156: 151: 144: 140: 136: 133: 129: 126:Invention of 125: 121: 117: 113: 108: 104: 101: 97: 92: 82: 78: 73: 56: 52: 45: 40: 33: 30: 19: 5692:Svante Pääbo 5629:Hideo Hosono 5599:Jean FrĂ©chet 5581:Brian Druker 5577:Janet Rowley 5559:Ken Thompson 5476:Makoto Nagao 5438:Anne McLaren 5379:Jozef Schell 5307:Gerhard Ertl 5301:John J. Wild 5287:Dan McKenzie 5252:Robert Gallo 5244:Frank Fenner 5222:Gurdev Khush 5115: 5064:Robert Fogel 4943: 4811:George Smith 4691:Akira Suzuki 4647:Gerhard Ertl 4631:Yves Chauvin 4579:John B. Fenn 4567:Ryoji Noyori 4554:2001–present 4528:Ahmed Zewail 4488:Harold Kroto 4472:Mario Molina 4447: 4400:Robert Huber 4372:John Polanyi 4356:Jerome Karle 4292:Georg Wittig 4177:Derek Barton 4169:Lars Onsager 4121:Giulio Natta 4117:Karl Ziegler 4109:John Kendrew 3877:Richard Kuhn 3802:Hans Fischer 3618:Otto Wallach 3554:Emil Fischer 3485: 3458:the original 3453: 3421:the original 3408: 3383:. Retrieved 3373: 3361:. Retrieved 3357:the original 3347: 3336:, retrieved 3332:the original 3326: 3320: 3309:, retrieved 3305:the original 3300:Hall of Fame 3299: 3292: 3279: 3270: 3258:. Retrieved 3254:the original 3244: 3236:the original 3231: 3222: 3203: 3176:. Retrieved 3166: 3154:. Retrieved 3150:the original 3140: 3128:. Retrieved 3124:MyNewsLA.com 3123: 3115: 3103:. 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Index

Kary Banks Mullis

Lenoir, North Carolina
Newport Beach, California
Georgia Institute of Technology
BS
University of California, Berkeley
PhD
polymerase chain reaction
TaqMan
William Allan Award
Robert Koch Prize
Nobel Prize in Chemistry
Japan Prize
Molecular biology
Thesis
Doctoral advisor
J. B. Neilands
karymullis.com
biochemist
polymerase chain reaction
Nobel Prize in Chemistry
Michael Smith
Japan Prize
biochemistry
molecular biology
The New York Times
downplayed humans' role in climate change
doubt that HIV is the cause of AIDS
astrology

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