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Lytta vesicatoria

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Each beetle contains some 0.2–0.7 mg of cantharidin, males having significantly more than females. The beetle secretes the agent orally, and exudes it from its joints as a milky fluid. The potency of the insect as a blistering agent has been known since antiquity and the activity has been used
406:, increasing the value of mating to the female, and thus increasing the male's reproductive fitness. Zoologists note that the conspicuous coloration, the presence of a powerful toxin, and the adults' aggregating behaviour in full view of any predators strongly suggest 579:
Preparations of Spanish fly and its active agent have been implicated in both inadvertent and intentional poisonings. Arthur Kendrick Ford was imprisoned in 1954 for the unintended deaths of two women surreptitiously given candies laced with
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While most commonly available preparations of Spanish fly contain cantharidin in negligible amounts, if at all, the chemical is available illicitly in concentrations capable of causing severe toxicity.
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Medicines, their uses and mode of administration; including a complete conspectus of the three British Pharmacopoeias, an account of all the new remedies, and an Appendix of Formulae
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In the 19th century, Spanish fly was used externally mainly as blistering agent and local irritant; also, in chronic gonorrhoea, paralysis, lepra, ulcers therapy.
2450: 1675: 1399: 371:, claw). The bee carries the larvae back to its nest, where they feed on bee larvae and the bees' food supplies. The larvae are thus somewhere between 2517: 2385: 2424: 1045: 1131: 1959: 683: 1584: 1515: 1482: 1016: 1078: 2550: 1450: 1374: 1345: 1309: 1273: 1233: 1188: 923: 1066: 918:. Vol. 3, Insects (2nd ed.). Farmington Hills, Michigan: Thomson-Gale/American Zoo and Aquarium Association. p. 331. 1623: 946: 1668: 1684: 1041: 328:
An aggregation of Spanish fly adults in Siberia. The behaviour and their toxicity suggest that their conspicuous coloration is
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The Spanish fly is found across Eurasia, though it is a mainly a southern European species, with some records from southern
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Cutler, Horace G. (1992). "An Historical Perspective of Ancient Poisons". In Nigg, Herbert N.; Seigler, David S. (eds.).
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Karras, David J.; Farrell, S. E.; Harrigan, R. A.; et al. (1996). "Poisoning From "Spanish Fly" (Cantharidin)".
2364: 2575: 2565: 2555: 2455: 2187: 2167: 1645: 521:, beetle), obtained from dried and ground beetles. The crushed powder is of yellow-brown to brown-olive color with 398:, for which the beetle is known, is synthesised only by males; females obtain it from males during mating, as the 2377: 1539: 295: 2560: 2152: 2147: 679: 881: 513:
in various ways. This has led to its small-scale commercial preparation and sale, in a powdered form known as
67: 2054: 2031: 1944: 1602:"Prevention of Rabies by Application of Lytta vesicatoria in Persian Medicine Texts in Islamic Civilization" 1571: 1507: 2250: 2119: 561: 267: 251: 2325: 2288: 2212: 2104: 1894: 1889: 1740: 162: 552:. It causes irritation, blistering, bleeding and discomfort. These effects can escalate to erosion and 347:
The female lays her fertilised eggs on the ground, near the nest of a ground-nesting solitary bee. The
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Currently the cantharidin in US, in the form of collodion, is used in the treatment of warts and
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are very active as soon as they hatch. They climb a flowering plant and await the arrival of a
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sometimes included as a minor ingredient "green metallic beetles", inferred to be
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in each system, sometimes followed by severe gastro-intestinal bleeding and
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Blood, Douglas Charles; Studdert, Virginia P.; Gay, Clive C., eds. (2007).
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larvae for the remaining two or more instars, in a development type called
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Male Nuptial Gifts: Phenotypic Consequences and Evolutionary Implications
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This article is about the insect species. For other uses of the term
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Gwaltney-Brant, Sharon M.; Dunayer, Eric; Youssef, Hany (2012).
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Lytta vesicatoria (Linnaeus, 1758), Taxonomic Serial No.: 114404
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reflections, is of disagreeable scent, and is bitter to taste.
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preparations as "Cantharides". The insect is the source of the
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Moallemi, Mostafa; Yousofpour, Mohammad; Jokar, Assie (2021).
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The species and others in its family were used in traditional
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The adult Spanish fly is a slender, soft-bodied metallic and
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Mosby's Dictionary of Complementary and Alternative Medicine
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Boggs, Carol L. (1995). Leather, S. R.; Hardie, J. (eds.).
1304:(3rd ed.). Philadelphia, PA, USA: Elsevier Saunders. 1147:
Robiquet, M. (1810). "Expériences sur les cantharides".
952:. Institute of Tropical Medicine Antwerp. Archived from 548:
Cantharidin is dangerously toxic, inhibiting the enzyme
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Species of beetle that produces a toxic blistering agent
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and other parts of North Africa, spice blends known as
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Criminal Poisoning: Clinical and Forensic Perspectives
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An extract from the beetle was thought to be a strong
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Veterinary Toxicology: Basic and Clinical Principles
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Phytochemical Resources for Medicine and Agriculture
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The Death of George Washington: He Died as He Lived
1499: 1261: 1268:(3rd ed.). Philadelphia, PA, USA: Elsevier. 533:, and is produced by some other insects, such as 1441:. In Hooser, Stephen; McQueen, Charlene (eds.). 1336:. In Hooser, Stephen; McQueen, Charlene (eds.). 1334:"Comparative Gastrointestinal Toxicity (Ch. 16)" 1226:APC Textbook of Forensic Medicine and Toxicology 568:destruction, resulting in gastro-intestinal and 302:in 1775. He reclassified the Spanish fly as the 1649:. Vol. V (9th ed.). 1878. p. 31. 882:"Cantharidin and insects: an historical review" 659:, the beetles were mixed with human excrement, 797: 795: 1669: 1034:"Geographic Information: Geographic Division" 751:Liddell, Henry George; Scott, Robert (1940). 728:Liddell, Henry George; Scott, Robert (1940). 8: 1264:Saunders Comprehensive Veterinary Dictionary 1170: 1168: 1166: 1164: 1162: 875: 873: 701:was used internally as a diuretic stimulant 214:family (Meloidae). It is distributed across 1228:. New Delhi, India: Avichal. p. 652f. 730:"λύττα, λυττάω, λυττητικός, etc., v. λυσς-" 2245: 1706: 1676: 1662: 1654: 1400:The American Journal of Emergency Medicine 425:Adult beetles primarily feed on leaves of 53: 42: 1498:Davidson, Alan (1999). Jaine, Tom (ed.). 810:. Huntingdon Valley, Pennsylvania: Farlex 258:), meaning martial rage, raging madness, 779:Latin Dictionary & Grammar Resources 596:, the condition which caused his death. 1624:Is "Spanish Fly" really an aphrodisiac? 1046:Integrated Taxonomic Information System 775:"Latin definition for: vesica, vesicae" 720: 1960:List of crop plants pollinated by bees 1204:the active agent appears variously as 1130:Neligan, J. M.; Macnamara, R. (1867). 1208:, and "cantharadin" or "canthariadin" 1107:Lytta (Lytta) vesicatoria vesicatoria 1079:UK Centre for Ecology & Hydrology 584:, which he had intended to act as an 410:among the blistering meloid beetles. 7: 2378:a5f253ae-22dc-4e60-a6de-5215f6df72f7 1606:Traditional and Integrative Medicine 1332:Evans, T. J.; Hooser, S. B. (2010). 517:(from the plural of Greek κανθαρίς, 383:into very different, more typically 1538:Green, Jonathon (12 October 2002). 1136:. Fanin & Company. p. 297. 667:to make the world's first recorded 639:, pistachio nuts, sugar, orange or 916:Grzimek's Animal Life Encyclopedia 912:"Coleoptera (beetles and weevils)" 25: 808:Farlex Partner Medical Dictionary 690:(ذراریـح), to attempt to prevent 592:was treated with Spanish fly for 2229: 1222:"VII. Spanish Fly (Cantharides)" 340:golden-green insect, one of the 66: 1042:United States Geological Survey 18:Lytta vesicatoria (Spanish fly) 2075:Home-stored product entomology 829:Selander, Richardg B. (1991). 445:. It is occasionally found on 1: 2158:Decline in insect populations 1751:List of insect-inspired songs 1413:10.1016/S0735-6757(96)90158-8 1365:. In Gupta, Ramesh C. (ed.). 1296:Jonas, Wayne B., ed. (2005). 588:. It has been suggested that 402:contains some. This may be a 1502:The Oxford Companion to Food 1473:Henriques, Peter R. (2000). 1220:Aggrawal, Anil, ed. (2007). 910:Schlager, Neil, ed. (2004). 886:The Great Lakes Entomologist 36:Spanish fly (disambiguation) 1032:Guala, Gerald, ed. (2015). 1009:10.1007/978-1-4899-2584-8_1 686:applied Spanish fly, named 290:is in an unrelated family, 2592: 2188:Pesticide toxicity to bees 2168:List of endangered insects 1175:Froberg, Blake A. (2010). 481: 478:Preparation of cantharidin 298:corrected its name in his 29: 2551:Beetles described in 1758 2226: 880:Young, Daniel K. (1984). 529:, the active agent, is a 296:Johan Christian Fabricius 254:is from the Greek λύττα ( 168: 161: 63:Scientific classification 61: 52: 45: 2153:Colony collapse disorder 2148:Bees and toxic chemicals 1443:Comprehensive Toxicology 1338:Comprehensive Toxicology 852:Selander, R. B. (1991). 2055:Insect bites and stings 2032:Drosophila melanogaster 1945:Biological pest control 1646:Encyclopædia Britannica 1572:Riding the Iron Rooster 1540:"Spoonfuls of paradise" 1508:Oxford University Press 544:Toxicity and poisonings 461:Interaction with humans 394:The defensive chemical 320:Description and ecology 2120:Rats, Lice and History 1437:Wilson, C. R. (2010). 562:acute tubular necrosis 495: 474: 333: 270:is derived from Latin 246:Etymology and taxonomy 2105:Alfred Russel Wallace 1890:Entomological warfare 1741:Insects in literature 1575:. Ivy Books. p.  755:. Liddell & Scott 732:. Liddell & Scott 491: 468: 327: 284:, although the genus 282:Cantharis vesicatoria 2373:Fauna Europaea (new) 2060:Insect sting allergy 1854:Cicadas in mythology 1040:. Reston, Virginia: 379:. The active larvae 300:Systema entomologiae 198:, also known as the 2163:Habitat destruction 1915:Insects in religion 1640:"Cantharides"  1075:UK Beetle Recording 988:. pp. 215–242. 712:were named thusly. 359:larvae their name, 280:was formerly named 154:L. vesicatoria 2571:Insects in culture 2494:Meloe vesicatorius 2236:Insects portal 2208:Insects and humans 1736:Arthropods in film 1685:Human interactions 1085:on 4 November 2017 959:on 20 January 2022 496: 475: 389:hypermetamorphosis 334: 2576:Parasites of bees 2566:Beetles of Europe 2556:Poisonous animals 2533: 2532: 2477:Open Tree of Life 2303:Lytta_vesicatoria 2289:Lytta vesicatoria 2259:Lytta vesicatoria 2251:Taxon identifiers 2242: 2241: 2131:Insect Literature 2088: 2087: 1987:Carmine/Cochineal 1940:Beneficial insect 1910:Insects in ethics 1859:Scarab (artifact) 1849:Bees in mythology 1758:Insects on stamps 1586:978-0-8041-0454-8 1517:978-0-19-211579-9 1510:. p. 671ff. 1484:978-0-931917-35-6 1149:Annales de Chimie 1071:(Linnaeus, 1758)" 1069:Lytta vesicatoria 1018:978-1-4899-2586-2 590:George Washington 570:renal dysfunction 414:Range and habitat 306:of the new genus 278:Lytta vesicatoria 195:Lytta vesicatoria 191: 190: 172:Lytta vesicatoria 47:Lytta vesicatoria 16:(Redirected from 2583: 2526: 2525: 2513: 2512: 2511: 2485: 2484: 2472: 2471: 2459: 2458: 2446: 2445: 2443:NBNSYS0000024945 2433: 2432: 2420: 2419: 2407: 2406: 2394: 2393: 2381: 2380: 2368: 2367: 2355: 2354: 2342: 2341: 2329: 2328: 2316: 2315: 2306: 2305: 2293: 2292: 2291: 2278: 2277: 2276: 2246: 2234: 2233: 2110:Jean-Henri Fabre 1885:Cricket fighting 1880:Cockroach racing 1746:Insects in music 1707: 1678: 1671: 1664: 1655: 1650: 1642: 1626: 1620: 1614: 1613: 1597: 1591: 1590: 1563: 1557: 1556: 1554: 1552: 1535: 1529: 1528: 1526: 1524: 1505: 1495: 1489: 1488: 1470: 1464: 1463: 1461: 1459: 1434: 1428: 1427: 1394: 1388: 1387: 1385: 1383: 1358: 1352: 1351: 1329: 1323: 1322: 1320: 1318: 1293: 1287: 1286: 1284: 1282: 1267: 1253: 1247: 1246: 1244: 1242: 1217: 1211: 1201: 1199: 1197: 1172: 1157: 1156: 1144: 1138: 1137: 1127: 1121: 1120: 1118: 1116: 1101: 1095: 1094: 1092: 1090: 1081:. 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Paul 1562: 1559: 1547: 1546: 1541: 1534: 1531: 1519: 1513: 1509: 1504: 1503: 1494: 1491: 1486: 1480: 1476: 1469: 1466: 1454: 1448: 1444: 1440: 1433: 1430: 1426: 1422: 1418: 1414: 1410: 1406: 1402: 1401: 1393: 1390: 1378: 1372: 1368: 1364: 1357: 1354: 1349: 1343: 1339: 1335: 1328: 1325: 1313: 1307: 1303: 1299: 1298:"Cantharides" 1292: 1289: 1277: 1271: 1266: 1265: 1259: 1258:"Cantharides" 1252: 1249: 1237: 1231: 1227: 1223: 1216: 1213: 1209: 1207: 1192: 1186: 1182: 1178: 1171: 1169: 1167: 1165: 1163: 1159: 1154: 1150: 1143: 1140: 1135: 1134: 1126: 1123: 1110: 1108: 1100: 1097: 1084: 1080: 1076: 1072: 1070: 1062: 1059: 1047: 1043: 1039: 1035: 1028: 1025: 1020: 1014: 1010: 1006: 1003:. p. 3. 1002: 995: 992: 987: 983: 982: 974: 971: 955: 948: 942: 939: 927: 921: 917: 913: 906: 904: 902: 900: 896: 892:(4): 187–194. 891: 887: 883: 876: 874: 870: 865: 861: 860: 859:Insecta Mundi 855: 848: 845: 840: 836: 835:Insecta Mundi 832: 825: 822: 809: 805: 798: 796: 792: 780: 776: 770: 767: 754: 747: 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Retrieved 723: 710:love potions 703: 698: 696: 687: 673: 654: 637:almond paste 627: 622: 616: 610: 598: 594:epiglottitis 578: 547: 534: 518: 514: 511: 497: 470: 443:white willow 424: 422:and Poland. 417: 404:nuptial gift 393: 368: 364: 363:(from Latin 353:solitary bee 346: 335: 307: 304:type species 299: 285: 281: 277: 276: 271: 255: 252:generic name 249: 237: 220: 199: 194: 193: 192: 171: 169: 153: 152: 140: 46: 40: 31: 2399:iNaturalist 2283:Wikispecies 2199:Categories, 2178:Insecticide 2009:Sericulture 1980:Royal jelly 1905:Flea circus 1895:Entomophagy 1829:Cantharidin 1824:Spanish fly 1799:In medicine 1779:Fly fishing 1710:In the arts 1612:(1): 70–77. 1551:14 February 1523:13 December 1458:14 December 1382:14 December 1317:14 December 1281:14 December 1241:14 December 1206:cantharidin 1196:16 December 1051:20 December 963:14 February 931:20 December 866:(2): 65–94. 841:(2): 65–94. 814:14 December 759:14 February 736:14 February 706:aphrodisiac 586:aphrodisiac 582:cantharidin 527:Cantharidin 515:cantharides 499:Cantharidin 493:Cantharidin 484:Cantharidin 471:Cantharides 469:Collecting 439:honeysuckle 435:amur privet 408:aposematism 396:cantharidin 385:scarabaeoid 361:triungulins 292:Cantharidae 274:, blister. 234:aphrodisiac 230:cantharidin 200:Spanish fly 32:Spanish fly 2540:Categories 2509:Q109599229 2218:Pesticides 1955:Bee pollen 1950:Beekeeping 1932:entomology 1875:Biomimicry 1807:Apitherapy 1767:In fishing 1722:Beetlewing 1703:in culture 1155:: 302–322. 1115:12 January 1089:12 January 784:19 January 716:References 669:stink bomb 651:Other uses 566:glomerular 538:immaculata 523:iridescent 507:strychnine 338:iridescent 330:aposematic 223:apothecary 204:aposematic 120:Coleoptera 100:Arthropoda 2201:templates 2173:Pesticide 1789:Fly tying 1177:"Animals" 986:CRC Press 665:wolfsbane 601:molluscum 531:terpenoid 519:Kantharis 377:parasites 373:predators 287:Cantharis 227:terpenoid 148:Species: 86:Kingdom: 80:Eukaryota 2546:Meloidae 2503:Wikidata 2417:10766870 2310:BioLib: 2268:Wikidata 2141:Concerns 2093:Pioneers 2070:Woodworm 1975:Propolis 1930:Economic 1817:Melittin 1812:Apitoxin 1569:(1989). 641:tamarind 628:Dawamesk 554:bleeding 536:Epicauta 314:Meloidae 202:, is an 180:Linnaeus 130:Meloidae 126:Family: 96:Phylum: 90:Animalia 76:Domain: 2523:4457221 2482:1076134 2391:1046592 2339:1220034 2274:Q624996 2065:Bed bug 2047:insects 2045:Harmful 2021:Shellac 1965:Beeswax 1920:Jingzhe 1700:insects 1696:Aspects 1689:insects 1421:8765116 753:"λύσσα" 688:ḏarārīḥ 661:arsenic 633:hashish 613:Morocco 369:ungulus 216:Eurasia 210:in the 136:Genus: 116:Order: 110:Insecta 106:Class: 2456:404363 2430:114404 2365:123716 2352:LYTTVE 2326:459352 2004:Kermes 1999:Chitin 1992:Polish 1583:  1514:  1481:  1449:  1419:  1373:  1344:  1308:  1272:  1232:  1210:(sic). 1202:Note: 1187:  1015:  922:  692:rabies 663:, and 645:cloves 643:peel, 558:mucosa 453:, and 357:instar 349:larvae 272:vesica 266:. The 264:rabies 208:beetle 34:, see 2469:23533 2412:IRMNG 2404:68005 2313:14466 1970:Honey 1687:with 957:(PDF) 950:(PDF) 431:lilac 381:moult 309:Lytta 262:, or 256:lytta 141:Lytta 2518:GBIF 2451:NCBI 2425:ITIS 2386:GBIF 2347:EPPO 2321:BOLD 2014:Silk 1581:ISBN 1553:2017 1525:2015 1512:ISBN 1479:ISBN 1460:2015 1447:ISBN 1417:PMID 1384:2015 1371:ISBN 1342:ISBN 1319:2015 1306:ISBN 1283:2015 1270:ISBN 1243:2015 1230:ISBN 1198:2015 1185:ISBN 1117:2017 1091:2018 1053:2015 1013:ISBN 965:2017 933:2015 920:ISBN 816:2015 786:2022 761:2017 738:2017 680:Rome 678:and 564:and 451:rose 447:plum 441:and 375:and 250:The 184:1758 2438:NBN 2334:EoL 2298:ADW 1698:of 1409:doi 1005:doi 674:In 655:In 611:In 556:of 455:elm 427:ash 365:tri 2542:: 2520:: 2505:: 2479:: 2466:: 2453:: 2440:: 2427:: 2414:: 2401:: 2388:: 2375:: 2362:: 2349:: 2336:: 2323:: 2300:: 2285:: 2270:: 1643:. 1608:. 1604:. 1579:. 1577:54 1542:. 1423:. 1415:. 1405:14 1403:. 1300:. 1260:. 1224:. 1161:^ 1153:76 1151:. 1077:. 1073:. 1044:, 1036:. 1011:. 984:. 914:. 898:^ 890:17 888:. 884:. 872:^ 862:. 856:. 837:. 833:. 806:. 794:^ 777:. 694:. 671:. 635:, 603:. 572:, 540:. 509:. 457:. 449:, 437:, 433:, 429:, 316:. 218:. 182:, 2133:) 2129:( 2123:) 2117:( 1677:e 1670:t 1663:v 1610:6 1589:. 1555:. 1527:. 1487:. 1462:. 1411:: 1386:. 1350:. 1321:. 1285:. 1245:. 1200:. 1119:. 1105:" 1093:. 1067:" 1055:. 1021:. 1007:: 967:. 935:. 864:5 839:5 818:. 788:. 763:. 740:. 332:. 186:) 178:( 38:. 20:)

Index

Lytta vesicatoria (Spanish fly)
Spanish fly (disambiguation)

Scientific classification
Edit this classification
Eukaryota
Animalia
Arthropoda
Insecta
Coleoptera
Meloidae
Lytta
Binomial name
Linnaeus
1758
aposematic
beetle
blister beetle
Eurasia
apothecary
terpenoid
cantharidin
aphrodisiac
ras el hanout
generic name
Bacchic frenzy
rabies
specific name
Cantharis
Cantharidae

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