244:
221:
118:
143:
495:
250:
149:
1662:
1614:
de Nooij-van Dalen AG, van Dongen GA, Smeets SJ, Nieuwenhuis EJ, Stigter-van Walsum M, Snow GB, Brakenhoff RH (2003). "Characterization of the human Ly-6 antigens, the newly annotated member Ly-6K included, as molecular markers for head-and-neck squamous cell carcinoma".
1429:
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library".
257:
156:
678:
79:
659:
1573:"Essential Role for the Lymphostromal Plasma Membrane Ly-6 Superfamily Molecule Thymic Shared Antigen 1 in Development of the Embryonic Adrenal Gland"
1731:
1175:"RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell"
1707:
1114:
1096:
1726:
1365:
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides".
243:
1134:"Identification through bioinformatics of cDNAs encoding human thymic shared Ag-1/stem cell Ag-2. A new member of the human Ly-6 family"
938:
1303:
Hossiny MA, Luo L, Frazier WR, Steiner N, Gusev Y, Kallakury B, Glasgow E, Creswell K, Madhavan S, Kumar R, Upadhyay G (2016-04-11).
945:
220:
1173:
Mao M, Yu M, Tong JH, Ye J, Zhu J, Huang QH, Fu G, Yu L, Zhao SY, Waxman S, Lanotte M, Wang ZY, Tan JZ, Chan SJ, Chen Z (Jul 1996).
1460:"Characterization and mapping to human chromosome 8q24.3 of Ly-6-related gene 9804 encoding an apparent homologue of mouse TSA-1"
1232:
1083:
1062:
1571:
Zammit DJ, Berzins SP, Gill JW, Randle-Barrett ES, Barnett L, Koentgen F, Lambert GW, Harvey RP, Boyd RL, Classon BJ (2002).
1079:
142:
117:
1058:
1495:"Physical and functional association between thymic shared antigen-1/stem cell antigen-2 and the T cell receptor complex"
1248:"Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome"
59:
1530:"Inhibition of the function of the FcΞ³RIIB by a monoclonal antibody to thymic shared antigen-1, a Ly-6 family antigen"
256:
155:
1700:
249:
148:
727:
67:
50:, RIG-E, RIGE, SCA-2, SCA2, TSA-1, lymphocyte antigen 6 complex, locus E, lymphocyte antigen 6 family member E
708:
704:
1693:
1186:
131:
46:
921:
907:
903:
899:
895:
891:
872:
846:
832:
828:
824:
820:
816:
801:
1640:
1305:"Ly6E/K signaling to TGF-Ξ² promotes breast cancer progression, immune escape and drug resistance"
91:
917:
876:
842:
797:
1632:
1602:
1559:
1516:
1481:
1446:
1417:
1382:
1342:
1324:
1285:
1267:
1214:
1155:
39:
1036:
1624:
1592:
1584:
1549:
1541:
1506:
1471:
1438:
1407:
1374:
1332:
1316:
1275:
1259:
1204:
1194:
1145:
336:
267:
211:
166:
1028:
1020:
494:
311:
87:
1493:
Kosugi A, Saitoh S, Noda S, Miyake K, Yamashita Y, Kimoto M, Ogata M, Hamaoka T (1998).
1190:
1677:
1554:
1529:
1337:
1304:
1280:
1247:
1597:
1572:
1442:
593:
588:
572:
567:
562:
557:
552:
536:
1720:
1545:
1378:
1209:
1174:
1032:
523:
1644:
1673:
1016:
329:
108:
71:
1588:
1458:
Shan X, Bourdeau A, Rhoton A, Wells DE, Cohen EH, Landgraf BE, Palfree RG (1998).
1320:
1412:
1395:
95:
1119:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1101:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1476:
1459:
1150:
1133:
412:
228:
125:
75:
1511:
1494:
1328:
1271:
1263:
1199:
1059:
ENSG00000160932 GRCh38: Ensembl release 89: ENSG00000278032, ENSG00000160932
623:
472:
350:
295:
282:
194:
181:
83:
1636:
1606:
1563:
1346:
1289:
1520:
1485:
1450:
1421:
1386:
1246:
Luo L, McGarvey P, Madhavan S, Kumar R, Gusev Y, Upadhyay G (2016-02-03).
1218:
1159:
1035:. Further research is required to validate Ly6E for translation research.
985:
980:
1019:
as determined by a survey of more than 130 published clinical studies of
969:
772:
753:
1001:
739:
690:
1628:
1024:
953:
645:
1661:
1027:
tissue samples and adjacent normal tissues. Ly6E is associated with
608:
604:
1669:
1008:
63:
1396:"A gain of novel tissue specificity in the human Ly-6 gene E48"
503:
1394:
Brakenhoff RH, van Dijk M, Rood-Knippels EM, Snow GB (1997).
1233:"Entrez Gene: LY6E lymphocyte antigen 6 complex, locus E"
319:
1681:
1132:
Capone MC, Gorman DM, Ching EP, Zlotnik A (Sep 1996).
1015:
is associated with poor survival outcome in multiple
484:
890:
865:
815:
790:
1075:
1073:
1071:
1054:
1052:
1050:
594:negative regulation of signaling receptor activity
266:
165:
16:Protein-coding gene in the species Homo sapiens
1080:GRCm38: Ensembl release 89: ENSMUSG00000022587
1701:
8:
1708:
1694:
887:
812:
619:
519:
307:
206:
103:
1596:
1553:
1510:
1475:
1411:
1336:
1279:
1208:
1198:
1149:
537:acetylcholine receptor inhibitor activity
1046:
589:cell surface receptor signaling pathway
443:cardiac muscle tissue of left ventricle
20:
553:integral component of plasma membrane
271:
232:
227:
170:
129:
124:
7:
1658:
1656:
862:
787:
763:
744:
718:
695:
669:
650:
489:
407:
345:
324:
14:
1004:that in humans is encoded by the
1660:
1546:10.1046/j.1365-2567.2001.01275.x
493:
255:
248:
242:
219:
154:
147:
141:
116:
563:anchored component of membrane
504:More reference expression data
473:More reference expression data
369:olfactory zone of nasal mucosa
1:
1732:Human chromosome 8 gene stubs
1589:10.1128/MCB.22.3.946-952.2002
1443:10.1016/S0378-1119(97)00411-3
1321:10.1158/0008-5472.CAN-15-2654
240:
139:
1680:. You can help Knowledge by
1413:10.4049/jimmunol.159.10.4879
1379:10.1016/0378-1119(94)90802-8
1727:Genes on human chromosome 8
1528:Ding L, Shevach EM (2001).
1031:and tumor immune escape in
373:stromal cell of endometrium
1748:
1655:
1477:10.4049/jimmunol.160.1.197
1151:10.4049/jimmunol.157.3.969
1011:. Increased expression of
427:superior surface of tongue
1115:"Mouse PubMed Reference:"
1097:"Human PubMed Reference:"
984:
979:
975:
968:
952:
939:Chr 8: 143.02 β 143.02 Mb
933:
914:
869:
858:
839:
794:
783:
770:
766:
751:
747:
738:
725:
721:
702:
698:
689:
676:
672:
657:
653:
644:
629:
622:
618:
602:
522:
518:
501:
492:
483:
470:
419:
410:
357:
348:
318:
310:
306:
289:
276:
239:
218:
209:
205:
188:
175:
138:
115:
106:
102:
57:
54:
44:
37:
32:
28:
23:
1512:10.1074/jbc.273.20.12301
1264:10.18632/oncotarget.7163
1179:Proc Natl Acad Sci U S A
946:Chr 15: 74.83 β 74.83 Mb
1200:10.1073/pnas.93.12.5910
389:upper lobe of left lung
273:15 D3|15 34.29 cM
998:Lymphocyte antigen 6E
234:Chromosome 15 (mouse)
568:extracellular region
132:Chromosome 8 (human)
1191:1996PNAS...93.5910M
361:right lobe of liver
1668:This article on a
728:ENSMUSG00000022587
582:Biological process
546:Cellular component
530:Molecular function
397:hippocampus proper
393:right frontal lobe
1689:
1688:
1629:10.1002/ijc.10903
1315:(11): 3376β3386.
995:
994:
991:
990:
964:
963:
929:
928:
884:
883:
854:
853:
809:
808:
779:
778:
760:
759:
734:
733:
715:
714:
685:
684:
666:
665:
614:
613:
514:
513:
510:
509:
479:
478:
466:
465:
455:perirhinal cortex
423:lactiferous gland
404:
403:
302:
301:
201:
200:
1739:
1710:
1703:
1696:
1664:
1657:
1648:
1610:
1600:
1567:
1557:
1524:
1514:
1489:
1479:
1454:
1425:
1415:
1390:
1351:
1350:
1340:
1300:
1294:
1293:
1283:
1258:(10): 11165β93.
1243:
1237:
1236:
1229:
1223:
1222:
1212:
1202:
1170:
1164:
1163:
1153:
1129:
1123:
1122:
1111:
1105:
1104:
1093:
1087:
1077:
1066:
1056:
977:
976:
948:
941:
924:
888:
879:
863:
859:RefSeq (protein)
849:
813:
804:
788:
764:
745:
719:
696:
670:
651:
620:
520:
506:
497:
490:
475:
415:
413:Top expressed in
408:
353:
351:Top expressed in
346:
325:
308:
298:
285:
274:
259:
252:
246:
235:
223:
207:
197:
184:
173:
158:
151:
145:
134:
120:
104:
98:
96:LY6E - orthologs
49:
42:
21:
1747:
1746:
1742:
1741:
1740:
1738:
1737:
1736:
1717:
1716:
1715:
1714:
1653:
1651:
1613:
1577:Mol. Cell. Biol
1570:
1527:
1505:(20): 12301β6.
1492:
1457:
1437:(1β2): 149β56.
1428:
1406:(10): 4879β86.
1393:
1364:
1360:
1358:Further reading
1355:
1354:
1309:Cancer Research
1302:
1301:
1297:
1245:
1244:
1240:
1231:
1230:
1226:
1172:
1171:
1167:
1131:
1130:
1126:
1113:
1112:
1108:
1095:
1094:
1090:
1078:
1069:
1057:
1048:
1043:
1029:drug resistance
1021:gene expression
986:View/Edit Mouse
981:View/Edit Human
944:
937:
934:Location (UCSC)
920:
916:
910:
906:
902:
898:
894:
875:
871:
845:
841:
835:
831:
827:
823:
819:
800:
796:
709:ENSG00000160932
707:
705:ENSG00000278032
598:
577:
573:plasma membrane
541:
502:
471:
462:
457:
453:
449:
445:
441:
439:cardiac muscles
437:
433:
429:
425:
411:
400:
395:
391:
387:
383:
379:
375:
371:
367:
363:
349:
293:
280:
272:
262:
261:
260:
253:
233:
210:Gene location (
192:
179:
171:
161:
160:
159:
152:
130:
107:Gene location (
58:
45:
38:
17:
12:
11:
5:
1745:
1743:
1735:
1734:
1729:
1719:
1718:
1713:
1712:
1705:
1698:
1690:
1687:
1686:
1665:
1650:
1649:
1617:Int. J. Cancer
1611:
1568:
1525:
1490:
1470:(1): 197β208.
1455:
1426:
1391:
1373:(1β2): 171β4.
1361:
1359:
1356:
1353:
1352:
1295:
1238:
1224:
1185:(12): 5910β4.
1165:
1124:
1106:
1088:
1067:
1045:
1044:
1042:
1039:
993:
992:
989:
988:
983:
973:
972:
966:
965:
962:
961:
959:
957:
950:
949:
942:
935:
931:
930:
927:
926:
912:
911:
885:
882:
881:
867:
866:
860:
856:
855:
852:
851:
837:
836:
810:
807:
806:
792:
791:
785:
781:
780:
777:
776:
768:
767:
761:
758:
757:
749:
748:
742:
736:
735:
732:
731:
723:
722:
716:
713:
712:
700:
699:
693:
687:
686:
683:
682:
674:
673:
667:
664:
663:
655:
654:
648:
642:
641:
636:
631:
627:
626:
616:
615:
612:
611:
600:
599:
597:
596:
591:
585:
583:
579:
578:
576:
575:
570:
565:
560:
555:
549:
547:
543:
542:
540:
539:
533:
531:
527:
526:
516:
515:
512:
511:
508:
507:
499:
498:
487:
481:
480:
477:
476:
468:
467:
464:
463:
461:
460:
456:
452:
448:
444:
440:
436:
435:corneal stroma
432:
428:
424:
420:
417:
416:
405:
402:
401:
399:
398:
394:
390:
386:
382:
378:
374:
370:
366:
362:
358:
355:
354:
342:
341:
333:
322:
316:
315:
312:RNA expression
304:
303:
300:
299:
291:
287:
286:
278:
275:
270:
264:
263:
254:
247:
241:
237:
236:
231:
225:
224:
216:
215:
203:
202:
199:
198:
190:
186:
185:
177:
174:
169:
163:
162:
153:
146:
140:
136:
135:
128:
122:
121:
113:
112:
100:
99:
56:
52:
51:
43:
35:
34:
30:
29:
26:
25:
15:
13:
10:
9:
6:
4:
3:
2:
1744:
1733:
1730:
1728:
1725:
1724:
1722:
1711:
1706:
1704:
1699:
1697:
1692:
1691:
1685:
1683:
1679:
1675:
1671:
1666:
1663:
1659:
1654:
1646:
1642:
1638:
1634:
1630:
1626:
1623:(6): 768β74.
1622:
1618:
1612:
1608:
1604:
1599:
1594:
1590:
1586:
1583:(3): 946β52.
1582:
1578:
1574:
1569:
1565:
1561:
1556:
1551:
1547:
1543:
1539:
1535:
1531:
1526:
1522:
1518:
1513:
1508:
1504:
1500:
1499:J. Biol. Chem
1496:
1491:
1487:
1483:
1478:
1473:
1469:
1465:
1461:
1456:
1452:
1448:
1444:
1440:
1436:
1432:
1427:
1423:
1419:
1414:
1409:
1405:
1401:
1397:
1392:
1388:
1384:
1380:
1376:
1372:
1368:
1363:
1362:
1357:
1348:
1344:
1339:
1334:
1330:
1326:
1322:
1318:
1314:
1310:
1306:
1299:
1296:
1291:
1287:
1282:
1277:
1273:
1269:
1265:
1261:
1257:
1253:
1249:
1242:
1239:
1234:
1228:
1225:
1220:
1216:
1211:
1206:
1201:
1196:
1192:
1188:
1184:
1180:
1176:
1169:
1166:
1161:
1157:
1152:
1147:
1144:(3): 969β73.
1143:
1139:
1135:
1128:
1125:
1120:
1116:
1110:
1107:
1102:
1098:
1092:
1089:
1085:
1081:
1076:
1074:
1072:
1068:
1064:
1060:
1055:
1053:
1051:
1047:
1040:
1038:
1037:
1034:
1033:breast cancer
1030:
1026:
1022:
1018:
1014:
1010:
1007:
1003:
999:
987:
982:
978:
974:
971:
967:
960:
958:
955:
951:
947:
943:
940:
936:
932:
925:
923:
919:
913:
909:
905:
901:
897:
893:
889:
886:
880:
878:
874:
868:
864:
861:
857:
850:
848:
844:
838:
834:
830:
826:
822:
818:
814:
811:
805:
803:
799:
793:
789:
786:
784:RefSeq (mRNA)
782:
775:
774:
769:
765:
762:
756:
755:
750:
746:
743:
741:
737:
730:
729:
724:
720:
717:
711:
710:
706:
701:
697:
694:
692:
688:
681:
680:
675:
671:
668:
662:
661:
656:
652:
649:
647:
643:
640:
637:
635:
632:
628:
625:
621:
617:
610:
606:
601:
595:
592:
590:
587:
586:
584:
581:
580:
574:
571:
569:
566:
564:
561:
559:
556:
554:
551:
550:
548:
545:
544:
538:
535:
534:
532:
529:
528:
525:
524:Gene ontology
521:
517:
505:
500:
496:
491:
488:
486:
482:
474:
469:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
421:
418:
414:
409:
406:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
359:
356:
352:
347:
344:
343:
340:
338:
334:
332:
331:
327:
326:
323:
321:
317:
313:
309:
305:
297:
292:
288:
284:
279:
269:
265:
258:
251:
245:
238:
230:
226:
222:
217:
213:
208:
204:
196:
191:
187:
183:
178:
168:
164:
157:
150:
144:
137:
133:
127:
123:
119:
114:
110:
105:
101:
97:
93:
89:
85:
81:
77:
73:
69:
65:
61:
53:
48:
41:
36:
31:
27:
22:
19:
1682:expanding it
1674:chromosome 8
1667:
1652:
1620:
1616:
1580:
1576:
1540:(1): 28β36.
1537:
1533:
1502:
1498:
1467:
1463:
1434:
1430:
1403:
1399:
1370:
1366:
1312:
1308:
1298:
1255:
1251:
1241:
1227:
1182:
1178:
1168:
1141:
1137:
1127:
1118:
1109:
1100:
1091:
1017:malignancies
1012:
1005:
997:
996:
922:NP_001361067
915:
908:NP_001157512
904:NP_001157511
900:NP_001157510
896:NP_001157509
892:NP_001157508
873:NP_001120685
870:
847:NM_001374138
840:
833:NM_001164040
829:NM_001164039
825:NM_001164038
821:NM_001164037
817:NM_001164036
802:NM_001127213
795:
771:
752:
726:
703:
677:
658:
638:
633:
451:right kidney
335:
328:
193:143,023,832
180:143,017,982
55:External IDs
18:
1023:studies on
431:gallbladder
381:right ovary
365:granulocyte
294:74,831,754
281:74,826,900
33:Identifiers
1721:Categories
1534:Immunology
1464:J. Immunol
1400:J. Immunol
1252:Oncotarget
1086:, May 2017
1065:, May 2017
1041:References
385:right lung
339:(ortholog)
76:HomoloGene
1672:on human
1329:0008-5472
1272:1949-2553
1138:J Immunol
918:NP_032555
877:NP_002337
843:NM_008529
798:NM_002346
624:Orthologs
459:esophagus
447:CA3 field
84:GeneCards
1645:42182637
1637:12516096
1607:11784869
1564:11576217
1347:27197181
1290:26862846
1082:–
1061:–
970:Wikidata
603:Sources:
558:membrane
377:placenta
1555:1783287
1521:9575182
1486:9551972
1451:9373149
1422:9366413
1387:8125298
1338:4910623
1281:4905465
1219:8650192
1187:Bibcode
1160:8757598
1084:Ensembl
1063:Ensembl
1002:protein
740:UniProt
691:Ensembl
630:Species
609:QuickGO
314:pattern
40:Aliases
1643:
1635:
1605:
1598:133557
1595:
1562:
1552:
1519:
1484:
1449:
1420:
1385:
1345:
1335:
1327:
1288:
1278:
1270:
1217:
1207:
1158:
1025:cancer
956:search
954:PubMed
773:Q64253
754:Q16553
646:Entrez
485:BioGPS
172:8q24.3
72:106651
64:601384
1676:is a
1641:S2CID
1210:39161
1000:is a
679:17069
639:Mouse
634:Human
605:Amigo
337:Mouse
330:Human
277:Start
212:Mouse
176:Start
109:Human
80:56411
1678:stub
1670:gene
1633:PMID
1603:PMID
1560:PMID
1517:PMID
1482:PMID
1447:PMID
1431:Gene
1418:PMID
1383:PMID
1367:Gene
1343:PMID
1325:ISSN
1286:PMID
1268:ISSN
1215:PMID
1156:PMID
1013:Ly6E
1009:gene
1006:LY6E
660:4061
320:Bgee
268:Band
229:Chr.
167:Band
126:Chr.
88:LY6E
60:OMIM
47:LY6E
24:LY6E
1625:doi
1621:103
1593:PMC
1585:doi
1550:PMC
1542:doi
1538:104
1507:doi
1503:273
1472:doi
1468:160
1439:doi
1435:200
1408:doi
1404:159
1375:doi
1371:138
1333:PMC
1317:doi
1276:PMC
1260:doi
1205:PMC
1195:doi
1146:doi
1142:157
290:End
189:End
92:OMA
68:MGI
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1070:^
1049:^
607:/
296:bp
283:bp
195:bp
182:bp
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