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Lancet letter (COVID-19)

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235:, pointing out that "origin story" of the virus was still missing key details and that an objective analysis necessitated "addressing some uncomfortable possibilities," including an accidental release from a laboratory. When asked by UnDark why he thought Daszak and others pushed so strongly against the possibility of a lab leak, Relman said they may have wanted to "deflect perceptions of their work as endangering humankind". 171:
to flag Daszak's conflict of interest, but received no response. Horton later responded in a UK parliament session. Horton said to the committee "We trust authors to be honest with us and authors trust us to deal with their work confidentially and appropriately. Sometimes that system breaks down, and
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published a letter from a group of 16 virologists, biologists, and biosecurity specialists saying that more evidence is needed before any definitive conclusions on the origins question and calling for further investigations into a lab leak. The letter stressed that "Research-related hypotheses are
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published an addendum, saying "There may be differences in opinion as to what constitutes a competing interest." It also invited Daszak and other authors of the letter to amend their competing interest statements. Daszak amended his statement to describe the research he has done in southeast Asia,
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Following the addendum to the first letter, the authors of the first letter published a second letter, reaffirming their view that the pandemic has natural origins. The letter asserted that "careful and transparent collection of scientific information" on every potential hypothesis, but that they
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that the letter had a "chilling effect" on scientific research and the scientific community by implying that scientists who "bring up the lab-leak theory ... are doing the work of conspiracy theorists". The letter was deemed to have "effectively ended the debate over COVID-19's origins before it
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letter "helped to guide almost a year of reporting, as journalists helped to amplify Daszak's message and to silence scientific and public debate." This affected reporting on the origins of the virus, "characterising the lab leak theory as unworthy of serious consideration".
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began". Further criticism of the letter was focused on the fact that, according to emails obtained through FOIA, members involved in producing the letter concealed their involvement "to create the impression of scientific unanimity" and failed to disclose conflicts.
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Stanley Perlman, who signed both letters, said the original letter addressed the lab leak bioengineering scenario only and that the second letter addresses the scenario where a natural virus was accidentally released.
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reported Calisher had "completely changed his position", saying he believes that "there is too much coincidence" to ignore the lab-leak theory and that "it is more likely that it came out of that lab."
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The Lancet had previously only published letters supporting the natural origin theory, the possibility that the virus emerged in the wild and spilled over to humans, probably via the wildlife trade.
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In an email to Undark Magazine, Stanley Perlman wrote that versions of the lab leak idea differed in whether they posited the virus was engineered in a lab before leaking, explaining that the
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that "Contrary to the letter writers' assertion, the idea that the virus might have escaped from a lab invoked accident, not conspiracy." Wade opined that the signatories of the
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saying "We must take hypotheses about both natural and laboratory spillovers seriously until we have sufficient data" and that "theories of accidental release from a lab and
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is reported to have said "I'm convinced that what happened is that the virus was brought to a lab, they started to work with it…and some sloppy individual brought it out".
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said that had the experiments being done at the laboratory in Wuhan been disclosed by those involved, he would have "at least asked questions" before signing the letter.
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was shocked by the letter and its complete dismissal the lab leak possibility, saying that it was apparent that "the science world was not playing above board."
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noted that the conflicts of interest involving virologists denying that the pandemic could have come from a laboratory in Wuhan were "simply unprecedented."
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said that the search should be "guided by scientific principles" that would consider multiple scenarios for the origin of the pandemic.
247:, three signatories' said that upon further reflection, they thought a laboratory accident was plausible enough to merit consideration. 1073: 771: 1535: 1339: 573: 507: 949: 199: 362:
not misinformation or conjecture" and that "Scientific journals should open their columns to in-depth analyses of all hypotheses."
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said that the letter's conclusion was premature, saying that some scientists "closed ranks", fearing for their careers and grants.
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spillover both remain viable." The letter also criticized the WHO report on covid origins for dismissing the lab-leak theory.
1545: 1540: 711:"I Visited a Chinese Lab at the Center of a Biosafety Debate. What I Learned Helps Explain the Clash Over COVID-19's Origins" 427:"Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19" 987: 377: 172:
in this particular case Peter Daszak should certainly have declared his competing interests right at the beginning."
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Calisher, Charles; Carroll, Dennis; Colwell, Rita; Corley, Ronald B.; Daszak, Peter; et al. (March 7, 2020).
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with various different institutions including the Wuhan Institute of Virology. Daszak also recused himself from
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of the COVID-19 disease. Different versions of the lab origin hypothesis present different scenarios in which a
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letter behaved as "poor scientists" for "assuring the public of facts they could not know for sure were true."
70: 121:, said they were focused on dispelling these rumours, though the letter did not make this distinguishment, as 391:
said scientists open to the possibility of a laboratory accident should not be labeled conspiracy theorists.
47:, and condemning theories suggesting that the virus does not have a natural origin, which it referred to as " 1530: 934: 180: 168: 152: 43:) was a statement made in support of scientists and medical professionals in China fighting the outbreak of 557: 271: 102: 1357:
Helden, Jacques van; Butler, Colin D.; Achaz, Guillaume; Canard, Bruno; et al. (October 16, 2021).
744:"Science and Technology Committee : Oral evidence: Reproducibility and Research Integrity, HC 606" 710: 311: 1091:
Calisher, Charles H.; Carroll, Dennis; Colwell, Rita; Corley, Ronald B.; et al. (July 17, 2021).
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on February 19, 2020, and signed by 27 prominent scientists, gaining a further 20,000 signatures in a
1250: 1192: 694: 62: 1359:"An appeal for an objective, open, and transparent scientific debate about the origin of SARS-CoV-2" 1492: 1463:"Let Scientific Evidence Determine Origin of SARS-CoV-2, Urge Presidents of the National Academies" 1146: 1058: 618: 384: 98: 1319: 1447: 1271: 1226: 1034: 823: 670: 364: 194: 17: 292:
Following criticisms from the public that Daszak had failed to disclose certain relationships,
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Bloom, Jesse D.; Chan, Yujia Alina; Baric, Ralph S.; Bjorkman, Pamela J.; et al. (2021).
1122: 892: 815: 662: 529:"Opinion | A preprint provides ammunition to conspiracy theories about SARS-CoV-2 origin" 456: 276: 82: 48: 1378: 1370: 1208: 1200: 1112: 1104: 1024: 1014: 882: 872: 805: 652: 487: 446: 438: 340: 1429:"Scientists in Lancet letter call for 'evidence-based' evaluation of Covid lab leak theory" 641:"The COVID-19 lab leak hypothesis: did the media fall victim to a misinformation campaign?" 1324: 743: 319: 248: 210: 157: 114: 90: 66: 1488:"Scientists battle over the ultimate origin story: Where did the coronavirus come from?" 1196: 1054:"UK scientist with links to Wuhan lab 'recuses himself' from inquiry into Covid origins" 593: 1383: 1358: 1267:"Another Group of Scientists Calls for Further Inquiry Into Origins of the Coronavirus" 1213: 1117: 1092: 1029: 1002: 887: 860: 451: 426: 221: 176: 1374: 1108: 1019: 442: 1519: 1230: 1038: 827: 674: 388: 189: 970:"Did the coronavirus leak from a lab? These scientists say we shouldn't rule it out" 1093:"Science, not speculation, is essential to determine how SARS-CoV-2 reached humans" 988:"Christian Drosten im Interview – "Warum hat er mich nicht einfach mal angerufen?"" 842:"Top Trump officials pushed the COVID-19 lab-leak theory. Investigators had doubts" 512: 315: 228: 139: 122: 794:"COVID-19: Lancet investigation into origin of pandemic shuts down over bias risk" 910: 861:"Opinion: To stop the next pandemic, we need to unravel the origins of COVID-19" 164: 1407:"Jury still out on lab-leak COVID-19 origins, researchers say in Lancet letter" 233:
Proceedings of the National Academy of Sciences of the United States of America
950:"Nature-based or lab leak? Unraveling the debate over the origins of COVID-19" 118: 94: 86: 58: 53: 476:"Prevalence in News Media of Two Competing Hypotheses about COVID-19 Origins" 1204: 1180: 877: 793: 640: 578: 533: 106: 1392: 1222: 1142:"Strongest evidence yet suggests natural origins for Covid, say scientists" 1126: 896: 819: 666: 492: 475: 460: 508:"Experts fear false rumours could harm Chinese cooperation on coronavirus" 598: 344: 217: 44: 1443:"COVID-19 origins: The Lancet's U-turn, Biden's take and the China link" 1320:"Scientists demand fresh investigation into coronavirus lab-leak theory" 930:"The Wuhan Lab Leak Question: A Disused Chinese Mine Takes Center Stage" 772:"The origin of COVID: Did people or nature open Pandora's box at Wuhan?" 167:
for "scientific propaganda and thuggery". Metzel wrote to Lancet editor
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virus. Some early rumors focused on the deliberate leak of a virus as a
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petition. The letter generated significant controversy over the alleged
1292: 1288:"COVID-19 lab leak theory cannot be ruled out, leading scientists say" 810: 657: 339:
In May 2021, a group of 18 prominent scientists published a letter in
553:"The Lab-Leak Theory: Inside the Fight to Uncover COVID-19's Origins" 368:
described The Lancet's decision to publish the letter as a "u-turn".
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to humans, including a laboratory-acquired infection of a natural or
690:"WHO adviser accuses COVID-19 lab-leak theory critics of 'thuggery'" 109:
or accidental leak of an engineered virus. Some signatories of the
1074:"Under-fire Lancet admits conflict of interest on lab-leak letter" 619:"Lab Leak: A Scientific Debate Mired in Politics — and Unresolved" 594:"Covid origins: Scientists weigh up evidence over virus's origins" 220:, Assistant Secretary of State for East Asian and Pacific Affairs 1246:"Group of scientists argues COVID-19 lab theory without evidence" 85:, rumors and speculation arose about the possible lab origins of 726:"Wuhan lab leak 'now the most likely origin of Covid', MPS told" 322:, who signed the first letter, did not sign the second letter. 911:"Stanford scientist calls for investigation of Wuhan lab leak" 1003:"Addendum: competing interests and the origins of SARS-CoV-2" 574:"The rise and fall of British virus hunter Peter Daszak" 928:
Jeremy Page; Betsy McKay; Drew Hinshaw (May 24, 2021).
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believe it unlikely that the virus leaked from a lab.
1340:"The Sudden Rise of the Coronavirus Lab-Leak Theory" 1162:"Nobody knows how to engineer a virus from scratch" 865:Proceedings of the National Academy of Sciences 163:The letter was criticized by media commentator 1318:Steer, George; Cookson, Clive (May 14, 2021). 8: 1265:Gorman, James; Zimmer, Carl (May 13, 2021). 401:Investigations into the origin of COVID-19 1382: 1212: 1116: 1028: 1018: 886: 876: 809: 656: 491: 450: 787: 785: 69:it had on scientists proposing that the 27:Controversial letter on COVID-19 origins 1001:Editors of The Lancet (June 26, 2021). 634: 632: 613: 611: 609: 546: 544: 417: 859:Relman, David A. (November 24, 2020). 1181:"Investigate the origins of COVID-19" 7: 792:Thacker, Paul D. (October 1, 2021). 266:letter focused more on engineering. 1427:Basu, Mohana (September 20, 2021). 724:Knapton, Sarah (15 December 2021). 709:Hvistendahl, Mara (June 19, 2021). 1286:Guy Faulconbridge (May 13, 2021). 97:progenitor of SARS-COV-2 may have 25: 639:Thacker, Paul D. (July 8, 2021). 200:Bulletin of the Atomic Scientists 125:insisted on a "broad statement". 551:Eban, Katherine (June 3, 2021). 527:Prasad, R. (February 20, 2020). 474:Rozado, David (24 August 2021). 18:Lancet letter (COVID-19 origins) 1300:from the original on 2021-11-25 1052:Gulland, Anne (June 22, 2021). 81:From the early outbreak of the 51:". The letter was published in 231:published an opinion piece in 1: 1375:10.1016/S0140-6736(21)02019-5 1244:Swanson, Ian (July 6, 2021). 1140:Newey, Sarah (July 6, 2021). 1109:10.1016/S0140-6736(21)01419-7 1020:10.1016/S0140-6736(21)01377-5 443:10.1016/S0140-6736(20)30418-9 198:science writer, wrote in the 1078:Times Higher Education (THE) 688:Lonas, Lexi (June 9, 2021). 378:National Academy of Sciences 372:National Academy of Sciences 301:s COVID-19 origins inquiry. 1562: 1536:Academic journal articles 269:In an interview with the 238: 1411:South China Morning Post 751:Committees.parliament.uk 406:COVID-19 lab leak theory 138:According to journalist 71:COVID-19 lab leak theory 65:of its authors, and the 1205:10.1126/science.abj0016 935:The Wall Street Journal 878:10.1073/pnas.2021133117 245:The Wall Street Journal 239:Signatories' statements 153:The Wall Street Journal 1413:. September 18, 2021. 493:10.3390/socsci10090320 1546:Medical controversies 1541:Biology controversies 1467:Nationalacademies.org 974:MIT Technology Review 383:In an interview with 150:In an interview with 63:conflicts of interest 37:(also referred to as 1369:(10309): 1402–1404. 1013:(10293): 2449–2450. 516:. February 20, 2020. 40:Calisher et al. 2020 1493:The Washington Post 1197:2021Sci...372..694B 917:. December 3, 2020. 871:(47): 29246–29248. 572:Spence, Madeleine. 385:The Washington Post 357:In September 2021, 272:Süddeutsche Zeitung 156:, social scientist 134:Critical commentary 49:conspiracy theories 1448:The Times of India 1272:The New York Times 1103:(10296): 209–211. 990:. 9 February 2022. 437:(10226): e42–e43. 365:The Times of India 275:in February 2022, 227:In November 2020, 209:Rutgers professor 811:10.1136/bmj.n2414 658:10.1136/bmj.n1656 625:. March 17, 2021. 330:Counterstatements 312:William B. Karesh 277:Christian Drosten 83:COVID-19 pandemic 73:be investigated. 16:(Redirected from 1553: 1510: 1509: 1507: 1505: 1500:on June 22, 2021 1496:. Archived from 1484: 1478: 1477: 1475: 1473: 1459: 1453: 1452: 1439: 1433: 1432: 1424: 1418: 1417: 1403: 1397: 1396: 1386: 1354: 1348: 1347: 1336: 1330: 1329: 1315: 1309: 1308: 1306: 1305: 1283: 1277: 1276: 1262: 1256: 1255: 1241: 1235: 1234: 1216: 1176: 1170: 1169: 1158: 1152: 1151: 1137: 1131: 1130: 1120: 1088: 1082: 1081: 1080:. 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Index

Lancet letter (COVID-19 origins)
COVID-19
conspiracy theories
The Lancet
Change.org
conflicts of interest
chilling effect
COVID-19 lab leak theory
COVID-19 pandemic
SARS-CoV-2
causative agent
bat-borne
spilled over
engineered
bioweapon
Stanley Perlman
Linda Saif
Daszak
Paul Thacker
The Wall Street Journal
Filippa Lentzos
Jamie Metzl
Richard Horton
Katherine Eban
Vanity Fair
Nicholas Wade
New York Times
Bulletin of the Atomic Scientists
Richard Ebright
Politico

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