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Lester Dragstedt

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and Michel Latarjet. However, he was especially influenced by A. J. Carlson, whom he would consider a mentor and advisor throughout his career, and Dragstedt pursued his studies of physiology. Dragstedt became a talented operating surgeon after practicing with animals and was attracted to surgery but
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was a long-time friend of the Dragstedts who was the local Lutheran minister but started teaching physiology at the University of Chicago and encouraged the Dragstedts to "send the boy to Chicago. They will found out in three months if he has any brains, and if he does not, you can bring him back to
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Lester Reynold Dragstedt was born in Anaconda, Montana to Swedish emigrant parents. His younger brother, Carl Albert, also became a doctor and surgeon. In his youth, his father encouraged him to memorize poetry including Bible passages and fragments of famous speeches. He was valedictorian of his
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He considered his vagotomy surgical technique "the most important contribution of his career". In a 1971 news interview, he revealed that he always believed "knowledge was the most important legacy one generation could bequeath to the next", and when he once asked his classmates how long
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to help design new research facilities for University of Chicago. After this, he was promoted to associate professor of surgery, eventually replacing Phemister as chair in 1947 and holding this position until his retirement in 1959 when he became professor emeritus.
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the following year. In 1918, he met Gladys Shoesmith, a student at Iowa and later married her in 1922. In 1916, he started as a physiologist and instructor of pharmacology at
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In 1936, he was one of three doctors from the University of Chicago's Department of Bacteriology, Surgery and Medicine who discovered a new germ, the apparent cause of
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Honorary Member of the Surgical Societies of Seattle, Los Angeles, Detroit, Minneapolis, Southern California, Graduate Surgeons of Los Angeles, and Boston
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which he called "my best experience in the Army" as he would perform autopsies from morning to night for about eight months. However, he contracted
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Lipotropic action of lipocaic: A study of the effect of oral and parenteral lipocaic and oral inositol on the dietary fatty liver of the white rat.
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and later had a urinary tract examination. Surgeon Herman Kretschmer found that Dragstedt had a unilateral tuberculosis kidney which required a
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Observations on a substance in pancreas (a fat metabolizing hormone) which permits survival and prevents liver changes in depancreatized dogs.
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1948–1959 Thomas D. Jones Distinguished Service Professor of Surgery and Chairman of the Department of Surgery, University of Chicago
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Lipotropic action of lipocaic. A study of the effects of lipocaic, methionine and cystine on dietary fatty livers in the white rat.
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Studies on the pathogenesis of tetany. VII. The prevention and control of parathyroid tetany by the oral administration of kaolin.
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Following his Chicago retirement, he moved to Florida where he became a full-time physiology and research professor at
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and Kretschmer and Dragstedt's brother Carl performed the surgery. In 1927, Dragstedt also survived a severe bout of
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In: Surgery of the Stomach and Duodenum, ed. H. N. Harkins and L. M. Nyhus, pp. 461–72. Boston: Little, Brown.
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Symposiums, named in his honour. The award "Lester R. Dragstedt Physician Scientist Award" was also named for him.
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1963 Distinguished Service Award of the American Medical Association for research, teaching, and surgical practice
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1964 Henry Jacob Bigelow Medal of the Boston Surgical Society for "Contributions to the Advancement of Surgery"
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Studies on the pathogenesis of tetany. V. The prevention and control of parathyroid tetany by calcium lactate.
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and duodenal ulcers and his work was documented in over 360 articles published in several medical journals.
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Studies on the pathogenesis of tetany. II. The mechanism involved in recovery from parathyroid tetany.
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Contributions to the physiology of the stomach. XXXVIII. Gastric juice in duodenal and gastric ulcers.
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of Sweden, bestowed by the King of Sweden, for "Outstanding Contributions to the Science of Surgery"
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would remain inhabitable and they responded two billion years, he chose teaching as his profession.
134:(2 October 1893 – 16 July 1975) was an American surgeon who was the first to successfully separate 2097: 1903:
Dragstedt, Lester R. (February 1976). "Some comments on the cause of gastric and duodenal ulcers".
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which caused him to lose 50 pounds (23 kg). He was also hard of hearing throughout his life.
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1923–1925 Professor and Head, Departments of Physiology and Pharmacology, Northwestern University
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In 1950, he and his team at the University of Chicago discovered a new organ in the stomach, the
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Supra-diaphragmatic section of vagus nerves and gastric secretion in patients with peptic ulcer.
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1969 Distinguished Service Award (the first) and Gold Medal of the American Surgical Association
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Studies on the pathogenesis of tetany. I. The control and cure of parathyroid tetany by diet.
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Potentiation between intestinal and gastric phases of acid secretion in Heidenhain pouches.
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Quantitative study of effect of antrum resection on gastric secretion in Pavlov pouch dogs.
199:, Dragstedt traveled abroad where his daughter Charlotte was born; his travels included to 2151: 1795: 1466: 253: 135: 104: 160:". In the beginning, Dragstedt thought of becoming a physicist after hearing lectures by 1880: 1849: 1407: 528: 350: 335: 228: 2227: 1871: 718:
1969 Silver Plaque of the Institute of Digestive Diseases and Nutrition of Mexico City
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degree in 1915, Masters of Physiology in 1916, Ph.D of Physiology in 1920 and finally
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With S. O. Evans, Jr., J. M. Zubiran, J. D. McCarthy, H. Ragins, and E. R. Woodward.
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The experimental use of lipocaic in the treatment of psoriasis. A preliminary report.
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Royal Academy of Arts and Sciences of Uppsala, Sweden (Foreign Corresponding Member)
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Effect of resection of antrum of stomach on gastric secretion in Pavlov pouch dogs.
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On the corrosive properties of bile and pancreatic juice on living tissue in dogs.
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In a 1971 letter, Dragstedt spoke of his time in the military, saying he went to
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1946 Gold Medal of the Illinois State Medical Society for original investigation
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A quantitative study of the effect of vagotomy on gastric secretion in the dog.
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Supra-diaphragmatic section of the vagus nerves in treatment of duodenal ulcer.
1374:"National Academy of Sciences: Biographical Memoirs: Lester Reynold Dragstedt" 1271:
Meissner's plexus and the mechanism of vagal stimulation of gastric secretion.
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Section of the vagus nerves to the stomach in the treatment of duodenal ulcer.
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The relation of lipocaic to the blood and liver lipids of depancreatized dogs.
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1950 Gold Medal of the American Medical Association for original investigation
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Since 1977, the UF College of Medicine Department of Surgery have held annual
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Stimulating effect of vagotomy on gastric secretion in Heidenhain pouch dogs.
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With E. R. Woodward, E. B. Tovee, H. A. Oberhelman, Jr., and W. B. Neal, Jr.
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He was particularly recognized for his contributions to the treatment of the
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With E. R. Woodward, W. B. Neal, Jr., P. V. Harper, Jr., and E. H. Storer.
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1959–1975 Research Professor of Surgery, University of Florida, Gainesville
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With C. F. Mountain, J. H. Landor, J. D. McCarthy, and P. V. Harper, Jr.
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He primarily studied at the University of Chicago, where he received his
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he felt physiology had "greater promise for innovative accomplishments".
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The Bromsulphalein liver function test as a method of assay of lipocaic.
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The nature of the toxemia of intestinal obstruction. Preliminary report.
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With J. M. Zubiran, A. E. Kark, J. A. Montalbetti, and C. J. L. Morel.
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With P. B. Donovan, D. E. Clark, W. C. Goodpasture, and C. Vermeulen.
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A simplified method for chemical induction of gastric hypersecretion.
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With D. E. Clark, O. C. Julian, C. Vermeulen, and W. C. Goodpasture.
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With C. Vermeulen, W. C. Goodpasture, P. B. Donovan, and W. A. Geer.
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An experimental study of the intoxication in closed intestinal loops.
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These are from the National Academy of Sciences Biographical Memoir.
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1917–1919 Assistant Professor of Physiology, State University of Iowa
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Effect of the administration of lipocaic and cholesterol in rabbits.
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Lipocaic and fatty infiltration of the liver in pancreatic diabetes.
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1969 Silver Plaque of the Association of Mexican Gastroenterologists
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high school and was offered a scholarship to schools including the
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Fellows of the American Association for the Advancement of Science
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1920–1923 Assistant Professor of Physiology, University of Chicago
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The etiology of gastric and duodenal ulcer. Experimental Studies.
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1961 Samuel D. Gross Prize of the Philadelphia Academy of Surgery
1402:"Lester Dragstedt, First Surgeon To Part Siamese Twins, Is Dead" 269: 1214:
With J. Barcena, C. M. Baugh, J. L. Bravo, and C. F. Mountain.
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With C. Vermeulen, D. E. Clark, O. C. Julian, and J. G. Allen.
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Pathogenesis of acute pancreatitis (acute pancreatic necrosis).
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Direct observations on the mechanism of pain in duodenal ulcer.
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1925–1930 Associate Professor of Surgery, University of Chicago
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1916 Assistant, Department of Physiology, University of Chicago
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before returning in 1919, after serving in the military during
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Corrosive effects of digestive juices on legs of living frogs.
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Experimental gastrojejunal ulcers due to antrum hyperfunction.
342:). He was a well-respected surgeon, renowned for his work on 869:
Effect of liver autolysis in vivo. Proc. Soc. Exp. Biol. Med.
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1965 Annual Award of the Gastrointestinal Research Foundation
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With D. R. Kemp, F. Herrera-Fernandez, and E. R. Woodward.
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Significance of Meissner's plexus in the gastrin mechanism.
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Honorary Memberships in Foreign Organizations and Societies
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Members of the United States National Academy of Sciences
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With W. C. Goodpasture, C. Vermeulen, and P. B. Donovan.
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With M. L. Montgomery, J. C. Ellis, and W. B. Matthews.
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With M. L. Montgomery, W. B. Matthews, and J. C. Ellis.
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The influence of parathyroidectomy on gastric secretion.
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1965 Gold Medal of the Surgical Society of Malmo, Sweden
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Fellows of the American Gastroenterological Association
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With E. R. Woodward, C. L. Park, Jr., and H. Schapiro.
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The resistance of various tissues to gastric digestion.
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With J. B. Weeks, G. C. Petridis, and E. R. Woodward.
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and spent nine months at a tuberculosis sanatorium in
2250:"American Medical Association (AMA) Award Recipients" 1216:
Effects of total pancreatectomy on gastric secretion.
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Studies on the site and mechanism of gastrin release.
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1930–1948 Professor of Surgery, University of Chicago
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Fellows of the American Academy of Arts and Sciences
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The pathogenesis of acute dilatation of the stomach.
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Fellows of the Royal College of Surgeons of England
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Fatal effect of the total loss of pancreatic juice.
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American Association for the Advancement of Science
117: 99: 91: 83: 75: 56: 37: 21: 1297:With G. Wickbom, M. A. Kamal, and E. R. Woodward. 1283:With J. R. N. Curt, J. Isaza, and E. R. Woodward. 619:Royal College of Physicians and Surgeons of Canada 1529:"That 'Churning' Feeling May Mean Stomach Ulcers" 676:for "Outstanding Achievement in Gastroenterology" 1311:With G. Wickbom, F. L. Bushkin, and C. Linares. 330:He developed a new surgical procedure (surgical 2174:"Lester R. Dragstedt Physician Scientist Award" 2039:"Teachers Respond To "Why Become A Professor"?" 1983:"New Clue Is Discovered To Stomach Ulcer Cause" 1850:"Gut Mucosal Healing: Is the Science Relevant?" 1823:"Trailblazing U of C's impressive achievements" 1719:"ADRENALIN AIDS ONLY FEW CASES, PROFESSOR SAYS" 1364: 1362: 1556:"Board Asks Action On University Construction" 1360: 1358: 1356: 1354: 1352: 1350: 1348: 1346: 1344: 1342: 1645:. North American Book Dist LLC. p. 121. 1174:Peptic ulcer and the adrenal stress syndrome. 553:Society for Experimental Biology and Medicine 8: 1864:American Society for Investigative Pathology 1209:The secretory effect of gastric transection. 1200:With C. M. Baugh, J. Barcena, and J. Bravo. 1158:With H. A. Oberhelman, Jr. and C. A. Smith. 876:Fatal effect of total loss of gastric juice. 121:University of Chicago, University of Florida 1081:With T. F. Thornton, Jr. and E. H. Storer. 1462:"SIAMESE TWINS SEPARATED IN 3½ HR.SURGERY" 1257:Localization of the gastrinproducing cell. 1139:Secretory studies on the isolated stomach. 701:1953 Honorary Professor of Surgery at the 638:Association of Mexican Gastroenterologists 29: 18: 2065:"Research on Animals Becomes Issue Again" 1879: 855:The physiology of the parathyroid glands. 513:Membership of organizations and societies 374:University of Florida College of Medicine 1615:. American Journal of Surgery. June 1993 1041:Arteriosclerosis in pancreatic diabetes. 674:American Gastroenterological Association 565:American Gastroenterological Association 1338: 1255:With C. de la Rosa and E. R. Woodward. 1144:With E. R. Woodward and R. R. Bigelow. 1123:With E. R. Woodward and R. R. Bigelow. 787:The pathogenesis of parathyroid tetany. 774:The pathogenesis of parathyroid tetany. 164:but was later influenced by physicians 103:First surgeon to successfully separate 2226:. academyofsurgery.org. Archived from 2147:"In The Community: Medical Symposiums" 1127:Proc. Soc. Exp. Biol. Med., 68:473-74. 1120:Proc. Soc. Exp. Biol. Med., 67:350-51. 1085:Proc. Soc. Exp. Biol. Med., 59:140-41. 1071:Proc. Soc. Exp. Biol. Med., 53:152-54. 977:With J. Van Prohaska and H. P. Harms. 945:Ulcus acidum of Meckel's diverticulum. 927:Proc. Soc. Exp. Biol. Med., 29:753-55. 899:Proc. Soc. Exp. Biol. Med., 28:110-11. 759:With J. J. Moorhead and F. W. Burcky. 739:With J. J. Moorhead and F. W. Burcky. 629:National Academy of Medicine of Mexico 2334:American Surgical Association members 2275:Waldemar Kaempffert (June 13, 1937). 1911:(2). Netherlands: Springer: 197–200. 878:Proc. Soc. Exp. Biol. Med., 26:305-7. 743:Proc. Soc. Exp. Biol. Med., 14:17-19. 672:1964 Julius Friedenwald Medal of the 614:Argentine Society of Gastroenterology 591:American Academy of Arts and Sciences 561:American Society for Clinical Surgery 386:National Society for Medical Research 7: 2012:"Operations With Music Latest Style" 957:With H. E. Haymond and J. C. Ellis. 890:Liver autolysis in vivo. Arch. Surg. 625:Royal College of Surgeons of England 518:American Organizations and Societies 484:1916–1917 Instructor, Pharmacology, 156:Anaconda and put him to work in the 1955:"Researchers Find New Stomach Duct" 1527:John F. Sembower (April 20, 1957). 1088:With D. E. Clark and M. L. Eilert. 913:Surg. Gynecol. Obstet., 52:1075-86. 244:Military training and health issues 974:Surg. Gynecol. Obstet., 62:118-20. 934:Surg. Gynecol. Obstet., 55:265—86. 806:With K. Phillips and A. C. Sudan. 14: 2010:Edward S. Kitch (June 18, 1950). 1740:"4 Members of Academy In Florida" 1688:Lippincott Williams & Wilkins 992:Lipocaic. A new pancreas hormone. 424:1920 Ph.D., University of Chicago 319:. He originated the skin-grafted 1821:Rackl, Lorilyn (2 August 1999). 1588:Baylor University Medical Center 587:Institute of Medicine of Chicago 421:1916 M.S., University of Chicago 418:1915 B.S., University of Chicago 355:Society for Experimental Biology 272:with Milton Winternitz and then 231:and at St. Rochus Hospital with 2349:Northwestern University faculty 1905:Digestive Diseases and Sciences 1438:. 11 April 1955. Archived from 1029:Arch. Intern. Med., 64:1017-38. 1015:J. Invest. Dermatol., 2:219-30. 776:J. Am. Med. Assoc, 79: 1593-94. 380:in 1975 at his lake house near 2252:. ama-assn.org. Archived from 2201:The Daytona Beach News-Journal 1799:. 17 July 1975. Archived from 1498:Rocky Mountain Medical Journal 1471:. pp. 1–2. Archived from 1460:Gibbons, Roy (30 March 1955). 570:American College of Physicians 549:American Physiological Society 1: 2384:People from Anaconda, Montana 2354:University of Florida faculty 2344:University of Chicago faculty 1872:10.1016/S0002-9440(10)64385-4 1855:American Journal of Pathology 947:J. Am. Med. Assoc, 101:20-22. 756:J. Am. Med. Assoc, 68:330-33. 557:American Surgical Association 384:. He was also a president of 1772:. 2 January 1936. p. 18 1381:National Academy of Sciences 1190:Am. J. Physiol., 174:219-25. 1148:Am. J. Physiol., 162:99-109. 1106:Am. J. Physiol., 147:346-51. 1092:Am. J. Physiol., 144:620-25. 1022:Am. J. Physiol., 127:755-60. 1001:Am. J. Physiol., 124:642-46. 981:Am. J. Physiol., 117:175-81. 837:Am. J. Physiol., 77:296-306. 803:Am. J. Physiol., 64:499-502. 655:American Medical Association 635:Academy of Surgery of France 580:American Medical Association 575:American College of Surgeons 524:National Academy of Sciences 448:1959 Docteur Honoris Causa, 390:Medical College of Wisconsin 252:after leaving Iowa to study 2155:. Florida, US. 1 March 1987 1494:"O. T. Clagett Lectureship" 1273:Gastroenterology, 55:76-80. 844:Am. J. Physiol., 77:314—20. 810:Am. J. Physiol., 65:368-78. 796:Am. J. Physiol., 64:424-34. 679:1964 Golden Plate from the 462:1973 Doctor Honoris Causa, 441:1953 Doctor Honoris Causa, 2410: 2339:University of Iowa faculty 2017:Spartanburg Herald-Journal 1680:Corman, Marvin L. (2005). 789:Am. J. Physiol., 63:408—9. 657:for original investigation 648:American Honors and Awards 2121:"Deaths: In Other Places" 1329:J. Surg. Res., 21:357-58. 994:Northwest Med., 37:33-36. 857:Physiol. Rev., 7:499-530. 703:University of Guadalajara 696:Foreign Honors and Awards 653:1945 Silver Medal of the 608:Surgical Society of Paris 605:Surgical Society of Lyons 443:University of Guadalajara 125: 110: 28: 1791:"Obituary 2 -- No Title" 1683:Colon and Rectal Surgery 1506:Colorado Medical Society 1430:"Medicine: Double Thais" 1372:; Wangensteen; Sarah D. 1315:Arch. Surg., 108:680-84. 1287:Arch. Surg., 105:709-12. 1162:Arch. Surg., 63:298-302. 823:Am. J. Physiol., 68:134. 763:J. Exp. Med., 25:421-39. 611:Swedish Surgical Society 584:Central Surgical Society 486:State University of Iowa 142:Early life and education 132:Lester Reynold Dragstedt 42:Lester Reynold Dragstedt 2379:Order of the Polar Star 2224:"Samuel D. Gross Prize" 1848:Basson, Marc D (2002). 1642:Encyclopedia of Montana 1469:(subscription required) 1301:Am. Surgeon, 39:571-81. 1259:Surg. Forum, 16:327-29. 1245:Arch. Surg., 87:512-15. 1176:Arch. Surg., 65:809-15. 1057:Arch. Surg., 44:260-67. 961:Arch. Surg., 28:232-91. 713:Order of the North Star 476:University Appointments 408:Honors and distinctions 361:to help calm patients. 217:Vienna General Hospital 190:Northwestern University 162:Robert Andrews Millikan 151:. Swedish physiologist 1639:Capace, Nancy (2000). 1218:Surg. Forum, 7:380-82. 1211:Surg. Forum, 7:375-79. 1204:Surg. Forum, 7:356—60. 1067:With F. M. Owens, Jr. 681:Academy of Achievement 2394:20th-century surgeons 2125:The Milwaukee Journal 2070:The Milwaukee Journal 1534:The Milwaukee Journal 930:With W. B. Matthews. 726:Selected bibliography 464:University of Uppsala 457:University of Florida 376:until his death of a 149:University of Chicago 2304:Ancestry.com records 2101:. September 20, 1958 2043:St. Petersburg Times 1744:St. Petersburg Times 1561:St. Petersburg Times 1442:on December 15, 2008 1370:Wangensteen, Owen H. 1141:Arch. Surg. 60:1-20. 799:With S. C. Peacock. 792:With S. C. Peacock. 429:Rush Medical College 340:peptic ulcer disease 323:in the treatment of 315:and diseases of the 268:and subsequently to 262:Edward Bright Vedder 153:Anton Julius Carlson 2098:The Palm Beach Post 2073:. November 19, 1960 2045:. November 24, 1971 1803:on October 22, 2012 1475:on October 22, 2012 1102:With M. L. Eilert. 923:With W. L. Palmer. 450:University of Lyons 402:Lester R. Dragstedt 258:Army Medical School 237:Dallas B. Phemister 174:Bachelor of Science 2230:on August 11, 2015 2204:. October 28, 1961 1917:10.1007/bf01072069 1564:. October 24, 1959 1043:Surgery, 8:353-61. 888:With J. C. Ellis. 874:With J. C. Ellis. 867:With J. C. Ellis. 840:With A. C. Sudan. 833:With A. C. Sudan. 382:Elk Lake, Michigan 325:ulcerative colitis 302:ulcerative colitis 197:Rockefeller Fellow 182:University of Iowa 178:Doctor of Medicine 68:Elk Lake, Michigan 2329:American surgeons 2256:on April 27, 2016 1746:. August 14, 1966 643:Honors and awards 539:Alpha Omega Alpha 466:, Uppsala, Sweden 250:Washington, D. C. 205:Fritz de Quervain 129: 128: 95:1920s–1970s 92:Years active 49:Anaconda, Montana 2401: 2292: 2291: 2289: 2287: 2272: 2266: 2265: 2263: 2261: 2246: 2240: 2239: 2237: 2235: 2220: 2214: 2213: 2211: 2209: 2196:"Doctor Honored" 2192: 2186: 2185: 2183: 2181: 2170: 2164: 2163: 2161: 2160: 2143: 2137: 2136: 2134: 2132: 2117: 2111: 2110: 2108: 2106: 2089: 2083: 2082: 2080: 2078: 2061: 2055: 2054: 2052: 2050: 2035: 2029: 2028: 2026: 2024: 2007: 2001: 2000: 1998: 1996: 1979: 1973: 1972: 1970: 1968: 1951: 1945: 1944: 1900: 1894: 1893: 1883: 1845: 1839: 1838: 1836: 1835: 1818: 1812: 1811: 1809: 1808: 1787: 1781: 1780: 1778: 1777: 1762: 1756: 1755: 1753: 1751: 1736: 1730: 1729: 1727: 1726: 1715: 1709: 1708: 1706: 1704: 1690:. p. 1574. 1677: 1664: 1663: 1661: 1659: 1636: 1625: 1624: 1622: 1620: 1609: 1600: 1599: 1597: 1595: 1580: 1574: 1573: 1571: 1569: 1552: 1546: 1545: 1543: 1541: 1524: 1518: 1517: 1515: 1513: 1490: 1484: 1483: 1481: 1480: 1457: 1451: 1450: 1448: 1447: 1426: 1420: 1419: 1417: 1416: 1398: 1392: 1391: 1389: 1388: 1378: 1366: 436:Honorary Degrees 338:(resulting from 266:Fort Leavenworth 254:typhoid vaccines 213:Anton Eiselsberg 63: 33: 23:Lester Dragstedt 19: 16:American surgeon 2409: 2408: 2404: 2403: 2402: 2400: 2399: 2398: 2309: 2308: 2300: 2295: 2285: 2283: 2274: 2273: 2269: 2259: 2257: 2248: 2247: 2243: 2233: 2231: 2222: 2221: 2217: 2207: 2205: 2194: 2193: 2189: 2179: 2177: 2172: 2171: 2167: 2158: 2156: 2152:Gainesville Sun 2145: 2144: 2140: 2130: 2128: 2127:. 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Index


Anaconda, Montana
Elk Lake, Michigan
conjoined twins
conjoined twins
University of Chicago
Anton Julius Carlson
copper smelter
Robert Andrews Millikan
Ivan Pavlov
Bachelor of Science
Doctor of Medicine
University of Iowa
World War I
Northwestern University
Rockefeller Fellow
Paris
Fritz de Quervain
Vienna
Anton Eiselsberg
Vienna General Hospital
Jakob Erdheim
Budapest
Eugen Pólya
Hümer Hültl
Dallas B. Phemister
Washington, D. C.
typhoid vaccines
Army Medical School
Edward Bright Vedder

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