Knowledge (XXG)

Lia Addadi

Source πŸ“

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Balaban, Nathalie Q.; Schwarz, Ulrich S.; Riveline, Daniel; Goichberg, Polina; Tzur, Gila; Sabanay, Ilana; Mahalu, Diana; Safran, Sam; Bershadsky, Alexander; Addadi, Lia; Geiger, Benjamin (2001). "Force and focal adhesion assembly: a close relationship studied using elastic micropatterned
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Geiger, Benjamin; Addadi, Lia; Bershadsky, Alexander; Safran, Sam; Mahalu, Diana; Sabanay, Ilana; Tzur, Gila; Goichberg, Polina; Riveline, Daniel (2001). "Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates".
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as an Associate Professor in 1988. She was promoted to full professor in 1993 and Head of the Structural Biology in 1994. She works on ordered crystal arrays and mineralised tissues. She has investigated the relationship between acidic proteins with
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Aizenberg, Joanna; Hanson, Jonathan; Koetzle, Thomas F.; Leiserowitz, Leslie; Weiner, Stephen; Addadi, Lia (1995). "Biologically Induced Reduction in Symmetry: A Study of Crystal Texture of Calcitic Sponge Spicules".
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Nudelman, Fabio; Gotliv, Bat Ami; Addadi, Lia; Weiner, Steve (February 2006). "Mollusk shell formation: Mapping the distribution of organic matrix components underlying a single aragonitic tablet in nacre".
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Her work has considered molecular recognition at crystal interfaces. When introduced to an organism, crystals appear as highly structured, repetitive macromolecular substrates. She studies
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Addadi, Lia; Joester, Derk; Nudelman, Fabio; Weiner, Steve (2006). "Mollusk Shell Formation: A Source of New Concepts for Understanding Biomineralization Processes".
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Addadi is interested in how macromolecules nucleate oriented growth, and how morphology changes through interactions with surfaces. Addadi looks at the structures of
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composites. She demonstrated that protein intercalation into the lattice can changes the texture and mechanical properties of the material. She showed that
302:. She demonstrated that macromolecules in the shells of mollusks determines the polymorphism of aragonite and calcite. She went on to establish the role of 368:
that are sensitive to specific crystalline organisations. She also investigates cross-talk between crystals and the biological environments they exist in.
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Addadi, Lia; Weiner, Steve; Albeck, Shira; Falini, Giuseppe (1996). "Control of Aragonite or Calcite Polymorphism by Mollusk Shell Macromolecules".
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Varsano, Neta; Beghi, Fabio; Elad, Nadav; Pereiro, Eva; Dadosh, Tali; Pinkas, Iddo; Perez-Berna, Ana J.; Jin, Xueting; Kruth, Howard S. (2018).
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can selectively adhere to the surfaces of crystals and nucleate further crystal growth. This can help too understand how diseases such as
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Weiner, S.; Raz, S.; Addadi, L. (2003). "Taking Advantage of Disorder: Amorphous Calcium Carbonate and Its Roles in Biomineralization".
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Planning and execution of a solid State "absolute" asymmetric dimerization and polymerization with quantitative Enantiomeric yield
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Planning and execution of a solid State "absolute" asymmetric dimerization and polymerization with quantitative Enantiomeric yield
1136: 1322: 1252: 215: 566: 411: 286: 255: 203: 111: 67: 451: 211: 303: 1342: 1162:"Two polymorphic cholesterol monohydrate crystal structures form in macrophage culture models of atherosclerosis" 1276: 1227: 1312: 1115: 1056: 955: 523: 274:. She started to work on crystal growth during her PhD, and by chance met Steve Weiner who was working on 30: 444: 365: 278:. Together they investigated many biominerals, including demonstrating the matrix sheets of crystals in 78: 1307: 1173: 978: 920: 857: 846:"Interactions between acidic proteins and crystals: stereochemical requirements in biomineralization" 754: 239: 62: 542: 1104: 1002: 944: 512: 271: 210:, interactions with cells and crystallisation in cell membranes. She was elected a member of the 199: 115: 671: 646: 128: 1209: 1191: 1096: 1088: 1045: 1037: 994: 936: 893: 875: 826: 790: 772: 720: 684: 504: 496: 291: 275: 267: 207: 101: 214:(NAS) in 2017 for β€œdistinguished and continuing achievements in original research”, and the 1199: 1181: 1080: 1029: 986: 928: 883: 865: 818: 780: 762: 712: 488: 358: 322: 140: 386: 382: 338: 318: 1177: 982: 924: 861: 758: 1204: 1161: 785: 742: 334: 170: 888: 845: 1301: 326: 311: 155: 1108: 1006: 948: 516: 346: 932: 390: 378: 230:
Lia Addadi (fifth from right) outside the David Lopatie Hall of Graduate studies
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Proceedings of the National Academy of Sciences of the United States of America
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in biomineralisation. Addadi identified that mollusks build their shells using
822: 457: 424: 398: 385:. She demonstrated that in cell culture crystals adopt a similar shape to the 354: 342: 307: 1195: 1092: 1041: 998: 940: 879: 776: 724: 716: 688: 500: 251: 1277:"Prof. Lia Addadi - Weizmann Wonder Wander - News, Features and Discoveries" 1228:"Prof. Lia Addadi - Weizmann Wonder Wander - News, Features and Discoveries" 1186: 870: 767: 350: 195: 1213: 1100: 1049: 1033: 990: 830: 794: 508: 897: 145: 345:. Addadi studies the formation pathways of these mineralised tissues in 1253:"(IUCr) Aminoff Prize 2011: biological minerals inspire for the future" 299: 295: 243: 1084: 492: 238:. She earned her bachelor's and master's degrees in chemistry at the 122: 567:"The American Philosophical Society Welcomes New Members for 2020" 389:
plaque that forms in cells, because they are formed from the same
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Foreign associates of the National Academy of Sciences
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tomography to identify the cholesterol inside cells.
206:. She works on crystallisation in biology, including 165: 151: 139: 121: 107: 97: 74: 58: 40: 21: 437:2009 Israel Chemical Society Prize for Excellence 314:, acid rich proteins and an amorphous precursor. 1328:Academic staff of Weizmann Institute of Science 1166:Proceedings of the National Academy of Sciences 850:Proceedings of the National Academy of Sciences 747:Proceedings of the National Academy of Sciences 35:Lia Addadi in the Weizmann Institute of Science 1348:Members of the American Philosophical Society 8: 616:"Past Prelog-Lecturers and Their Laudations" 420:1996 NIDR Prize for Distinguished Scientists 395:stochastic optical reconstruction microscopy 254:on the synthesis of chiral polymers at the 84:Member of the National Academy of Sciences 29: 18: 1203: 1185: 887: 869: 784: 766: 736: 734: 432:Technion – Israel Institute of Technology 417:1989 Israel Chemical Society Annual Award 353:bone. She was the first woman to win the 357:prelog prize in 1989. She was appointed 470: 414:Ernst David Bergmann prize in Chemistry 242:, and graduated in 1973. She moved to 1131: 1129: 1127: 1125: 610: 608: 361:of the faculty of chemistry in 2001. 7: 1333:Weizmann Institute of Science alumni 647:"Dorothy Crowfoot Hodgkin Symposium" 641: 639: 637: 635: 606: 604: 602: 600: 598: 596: 594: 592: 590: 588: 537: 535: 533: 377:(PNAS) considered the formation of 14: 442:Royal Swedish Academy of Sciences 1114: 1055: 954: 522: 844:Weiner, S.; Addadi, L. (1985). 427:Prelog Medal in Stereochemistry 371:Her inaugural year article for 258:, which she completed in 1979. 1022:Chemistry – A European Journal 705:Chemistry - A European Journal 571:American Philosophical Society 216:American Philosophical Society 1: 811:Journal of Structural Biology 412:Weizmann Institute of Science 287:Weizmann Institute of Science 266:After her PhD, Addadi joined 256:Weizmann Institute of Science 204:Weizmann Institute of Science 112:Weizmann Institute of Science 68:Weizmann Institute of Science 452:National Academy of Sciences 212:National Academy of Sciences 933:10.1126/science.271.5245.67 741:Ravindran, Sandeep (2018). 304:amorphous calcium carbonate 44:1950 (age 73–74) 1369: 1338:University of Padua alumni 823:10.1016/j.jsb.2005.09.009 161: 90: 28: 1318:Italian women scientists 717:10.1002/chem.19950010705 222:Early life and education 1187:10.1073/pnas.1803119115 871:10.1073/pnas.82.12.4110 768:10.1073/pnas.1810225115 285:Addadi returned to the 280:nacre (mother of pearl) 1323:Italian women chemists 1034:10.1002/chem.200500980 991:10.1002/adma.200300381 743:"QnAs with Lia Addadi" 231: 445:Gregori Aminoff Prize 366:monoclonal antibodies 229: 79:Gregori Aminoff Prize 670:Addadi, Lia (1979). 450:2017 Elected to the 1178:2018PNAS..115.7662V 1137:"Prelog Medal 1998" 1073:Nature Cell Biology 983:2003AdM....15..959A 925:1996Sci...271...67F 862:1985PNAS...82.4110A 759:2018PNAS..115.7644R 481:Nature Cell Biology 447:for Crystallography 262:Research and career 240:University of Padua 234:Addadi was born in 63:University of Padua 1141:ingentaconnect.com 971:Advanced Materials 460:Honorary Doctorate 405:Awards and honours 272:Harvard University 232: 200:structural biology 116:Harvard University 16:Israeli biochemist 1343:Women biochemists 1172:(30): 7662–7669. 856:(12): 4110–4114. 753:(30): 7644–7645. 341:form crystals in 276:biomineralization 268:Jeremy R. Knowles 208:biomineralization 194:(born 1950) is a 189: 188: 102:Biomineralization 92:Scientific career 1360: 1292: 1291: 1289: 1288: 1273: 1267: 1266: 1264: 1263: 1249: 1243: 1242: 1240: 1239: 1224: 1218: 1217: 1207: 1189: 1157: 1151: 1150: 1148: 1147: 1133: 1120: 1119: 1118: 1112: 1085:10.1038/35074532 1067: 1061: 1060: 1059: 1053: 1017: 1011: 1010: 966: 960: 959: 958: 952: 908: 902: 901: 891: 873: 841: 835: 834: 805: 799: 798: 788: 770: 738: 729: 728: 699: 693: 692: 678: 667: 661: 660: 658: 657: 643: 630: 629: 627: 626: 612: 583: 582: 580: 578: 563: 557: 556: 554: 553: 539: 528: 527: 526: 520: 493:10.1038/35074532 475: 185: 182: 180: 178: 176: 174: 172: 152:Notable students 141:Doctoral advisor 135: 33: 19: 1368: 1367: 1363: 1362: 1361: 1359: 1358: 1357: 1298: 1297: 1296: 1295: 1286: 1284: 1275: 1274: 1270: 1261: 1259: 1251: 1250: 1246: 1237: 1235: 1226: 1225: 1221: 1159: 1158: 1154: 1145: 1143: 1135: 1134: 1123: 1113: 1069: 1068: 1064: 1054: 1019: 1018: 1014: 977:(12): 959–970. 968: 967: 963: 953: 919:(5245): 67–69. 910: 909: 905: 843: 842: 838: 807: 806: 802: 740: 739: 732: 701: 700: 696: 676: 669: 668: 664: 655: 653: 651:www.chem.uzh.ch 645: 644: 633: 624: 622: 614: 613: 586: 576: 574: 565: 564: 560: 551: 549: 541: 540: 531: 521: 477: 476: 472: 467: 407: 387:atherosclerotic 383:atherosclerosis 339:atherosclerosis 323:immunoglobulins 319:crystal protein 264: 224: 169: 133: 114: 82: 66: 59:Alma mater 54: 45: 36: 24: 17: 12: 11: 5: 1366: 1364: 1356: 1355: 1350: 1345: 1340: 1335: 1330: 1325: 1320: 1315: 1310: 1300: 1299: 1294: 1293: 1281:weizmann.ac.il 1268: 1244: 1232:weizmann.ac.il 1219: 1152: 1121: 1079:(5): 466–472. 1062: 1028:(4): 980–987. 1012: 961: 903: 836: 817:(2): 176–187. 800: 730: 711:(7): 414–422. 694: 683:(PhD thesis). 681:weizmann.ac.il 662: 631: 584: 558: 529: 487:(5): 466–472. 469: 468: 466: 463: 462: 461: 454: 448: 438: 435: 428: 421: 418: 415: 406: 403: 335:osteoarthritis 327:serum albumins 263: 260: 250:supervised by 223: 220: 187: 186: 167: 163: 162: 159: 158: 153: 149: 148: 143: 137: 136: 125: 119: 118: 109: 105: 104: 99: 95: 94: 88: 87: 76: 72: 71: 60: 56: 55: 46: 42: 38: 37: 34: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 1365: 1354: 1351: 1349: 1346: 1344: 1341: 1339: 1336: 1334: 1331: 1329: 1326: 1324: 1321: 1319: 1316: 1314: 1313:Living people 1311: 1309: 1306: 1305: 1303: 1282: 1278: 1272: 1269: 1258: 1254: 1248: 1245: 1233: 1229: 1223: 1220: 1215: 1211: 1206: 1201: 1197: 1193: 1188: 1183: 1179: 1175: 1171: 1167: 1163: 1156: 1153: 1142: 1138: 1132: 1130: 1128: 1126: 1122: 1117: 1110: 1106: 1102: 1098: 1094: 1090: 1086: 1082: 1078: 1074: 1066: 1063: 1058: 1051: 1047: 1043: 1039: 1035: 1031: 1027: 1023: 1016: 1013: 1008: 1004: 1000: 996: 992: 988: 984: 980: 976: 972: 965: 962: 957: 950: 946: 942: 938: 934: 930: 926: 922: 918: 914: 907: 904: 899: 895: 890: 885: 881: 877: 872: 867: 863: 859: 855: 851: 847: 840: 837: 832: 828: 824: 820: 816: 812: 804: 801: 796: 792: 787: 782: 778: 774: 769: 764: 760: 756: 752: 748: 744: 737: 735: 731: 726: 722: 718: 714: 710: 706: 698: 695: 690: 686: 682: 675: 674: 666: 663: 652: 648: 642: 640: 638: 636: 632: 621: 617: 611: 609: 607: 605: 603: 601: 599: 597: 595: 593: 591: 589: 585: 572: 568: 562: 559: 548: 547:nasonline.org 544: 538: 536: 534: 530: 525: 518: 514: 510: 506: 502: 498: 494: 490: 486: 482: 479:substrates". 474: 471: 464: 459: 455: 453: 449: 446: 443: 439: 436: 434:Kolthof prize 433: 429: 426: 422: 419: 416: 413: 409: 408: 404: 402: 400: 396: 392: 388: 384: 380: 376: 375: 369: 367: 362: 360: 356: 352: 348: 344: 340: 336: 332: 328: 324: 320: 315: 313: 312:aspartic acid 309: 305: 301: 297: 293: 288: 283: 281: 277: 273: 269: 261: 259: 257: 253: 249: 245: 241: 237: 228: 221: 219: 217: 213: 209: 205: 201: 197: 193: 184: 168: 164: 160: 157: 156:Julia Mahamid 154: 150: 147: 144: 142: 138: 131: 130: 126: 124: 120: 117: 113: 110: 106: 103: 100: 96: 93: 89: 85: 80: 77: 73: 69: 64: 61: 57: 53: 49: 43: 39: 32: 27: 20: 1285:. Retrieved 1283:. 2018-11-27 1280: 1271: 1260:. Retrieved 1256: 1247: 1236:. Retrieved 1234:. 2006-10-31 1231: 1222: 1169: 1165: 1155: 1144:. Retrieved 1140: 1076: 1072: 1065: 1025: 1021: 1015: 974: 970: 964: 916: 912: 906: 853: 849: 839: 814: 810: 803: 750: 746: 708: 704: 697: 680: 672: 665: 654:. Retrieved 650: 623:. Retrieved 620:chab.ethz.ch 619: 575:. Retrieved 573:. 5 May 2020 570: 561: 550:. Retrieved 546: 543:"Lia Addadi" 484: 480: 473: 381:crystals in 372: 370: 363: 347:foraminifera 316: 284: 265: 233: 191: 190: 127: 108:Institutions 91: 1308:1950 births 391:cholesterol 379:cholesterol 343:body fluids 310:silk gels, 308:hydrophobic 292:biominerals 179:/Structural 1302:Categories 1287:2019-05-07 1262:2019-05-07 1238:2019-05-07 1146:2019-05-07 656:2019-05-07 625:2019-05-07 577:9 December 552:2019-05-07 465:References 458:ETH Zurich 425:ETH Zurich 399:soft X-ray 355:ETH Zurich 294:including 252:Meir Lahav 192:Lia Addadi 146:Meir Lahav 23:Lia Addadi 1196:0027-8424 1093:1476-4679 1042:1521-3765 999:1521-4095 941:0036-8075 880:0027-8424 777:0027-8424 725:0947-6539 689:884944865 501:1465-7392 351:zebrafish 196:professor 173:.weizmann 65:(BS, MS) 1257:iucr.org 1214:29967179 1109:20724861 1101:11331874 1050:16315200 1007:96531039 949:95357556 831:16413789 795:29967178 517:20724861 509:11331874 246:for her 218:(2020). 181:_Biology 1205:6065044 1174:Bibcode 979:Bibcode 921:Bibcode 913:Science 898:3858868 858:Bibcode 786:6065009 755:Bibcode 300:apatite 296:calcite 244:Rehovot 202:at the 183:/Addadi 166:Website 81:(2011) 1212:  1202:  1194:  1107:  1099:  1091:  1048:  1040:  1005:  997:  947:  939:  896:  889:397944 886:  878:  829:  793:  783:  775:  723:  687:  515:  507:  499:  134:(1979) 132:  123:Thesis 98:Fields 86:(2017) 75:Awards 1105:S2CID 1003:S2CID 945:S2CID 677:(PDF) 513:S2CID 456:2018 440:2011 430:2006 423:1998 410:1986 236:Padua 70:(PhD) 52:Italy 48:Padua 1210:PMID 1192:ISSN 1097:PMID 1089:ISSN 1046:PMID 1038:ISSN 995:ISSN 937:ISSN 894:PMID 876:ISSN 827:PMID 791:PMID 773:ISSN 721:ISSN 685:OCLC 579:2021 505:PMID 497:ISSN 397:and 359:dean 349:and 337:and 331:gout 325:and 298:and 41:Born 1200:PMC 1182:doi 1170:115 1081:doi 1030:doi 987:doi 929:doi 917:271 884:PMC 866:doi 819:doi 815:153 781:PMC 763:doi 751:115 713:doi 489:doi 270:at 248:PhD 198:of 177:.il 175:.ac 171:www 1304:: 1279:. 1255:. 1230:. 1208:. 1198:. 1190:. 1180:. 1168:. 1164:. 1139:. 1124:^ 1103:. 1095:. 1087:. 1075:. 1044:. 1036:. 1026:12 1024:. 1001:. 993:. 985:. 975:15 973:. 943:. 935:. 927:. 915:. 892:. 882:. 874:. 864:. 854:82 852:. 848:. 825:. 813:. 789:. 779:. 771:. 761:. 749:. 745:. 733:^ 719:. 707:. 679:. 649:. 634:^ 618:. 587:^ 569:. 545:. 532:^ 511:. 503:. 495:. 483:. 333:, 282:. 50:, 1290:. 1265:. 1241:. 1216:. 1184:: 1176:: 1149:. 1111:. 1083:: 1077:3 1052:. 1032:: 1009:. 989:: 981:: 951:. 931:: 923:: 900:. 868:: 860:: 833:. 821:: 797:. 765:: 757:: 727:. 715:: 709:1 691:. 659:. 628:. 581:. 555:. 519:. 491:: 485:3

Index


Padua
Italy
University of Padua
Weizmann Institute of Science
Gregori Aminoff Prize
Member of the National Academy of Sciences
Biomineralization
Weizmann Institute of Science
Harvard University
Thesis
Planning and execution of a solid State "absolute" asymmetric dimerization and polymerization with quantitative Enantiomeric yield
Doctoral advisor
Meir Lahav
Julia Mahamid
www.weizmann.ac.il/Structural_Biology/Addadi
professor
structural biology
Weizmann Institute of Science
biomineralization
National Academy of Sciences
American Philosophical Society

Padua
University of Padua
Rehovot
PhD
Meir Lahav
Weizmann Institute of Science
Jeremy R. Knowles

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