Knowledge (XXG)

Lim homeobox 9

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and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes
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when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants.
1119: 112: 1213:"Transcriptional control of axonal guidance and sorting in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1" 309: 208: 1316: 302: 201: 817: 120: 798: 1309: 1087: 184: 99: 983: 979: 958: 950: 920: 916: 895: 887: 144: 987: 954: 924: 891: 1244: 92: 40: 1293: 1234: 1224: 1095: 389: 320: 264: 219: 364: 140: 1239: 1212: 687: 682: 677: 672: 667: 662: 657: 652: 647: 642: 626: 610: 605: 600: 595: 590: 585: 580: 1336: 1262: 567: 124: 1289: 382: 161: 148: 1180:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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RNA polymerase II transcription regulatory region sequence-specific DNA binding
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Avraham O, Hadas Y, Vald L, Zisman S, Schejter A, Visel A, Klar A (2009).
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DNA-binding transcription factor activity, RNA polymerase II-specific
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positive regulation of transcription by RNA polymerase II
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dorsal spinal cord interneuron anterior axon guidance
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negative regulation of transcription, DNA-templated
1136: 1134: 1132: 1115: 1113: 1111: 319: 218: 678:regulation of transcription by RNA polymerase II 16:Protein-coding gene in the species Homo sapiens 1141:GRCm38: Ensembl release 89: ENSMUSG00000019230 1317: 8: 1120:GRCh38: Ensembl release 89: ENSG00000143355 1324: 1310: 1259:United States National Library of Medicine 713: 658:regulation of transcription, DNA-templated 563: 360: 259: 156: 58: 1238: 1228: 1086:gene family of developmentally expressed 1257:This article incorporates text from the 1107: 1070:that in humans is encoded by the LHX9 18: 324: 285: 280: 223: 182: 177: 7: 1274: 1272: 1296:. You can help Knowledge (XXG) by 1082:This gene encodes a member of the 969: 940: 906: 877: 853: 834: 808: 789: 763: 744: 596:transcription corepressor activity 542: 460: 398: 377: 14: 1090:. The encoded protein contains a 1276: 308: 301: 295: 272: 207: 200: 194: 169: 526:More reference expression data 1: 1348:Human chromosome 1 gene stubs 1194:"Entrez Gene: LIM homeobox 9" 643:cell population proliferation 581:sequence-specific DNA binding 293: 192: 1343:Genes on human chromosome 1 430:stromal cell of endometrium 1364: 1271: 1176:"Mouse PubMed Reference:" 1158:"Human PubMed Reference:" 1050: 1045: 1041: 1034: 1018: 1012:Chr 1: 138.83 – 138.85 Mb 1005:Chr 1: 197.91 – 197.94 Mb 999: 976: 947: 936: 913: 884: 873: 860: 856: 841: 837: 828: 815: 811: 796: 792: 783: 770: 766: 751: 747: 738: 723: 716: 712: 696: 566: 562: 550: 545: 536: 523: 472: 463: 410: 401: 371: 363: 359: 342: 329: 292: 271: 262: 258: 241: 228: 191: 168: 159: 155: 110: 107: 97: 90: 85: 66: 61: 44: 39: 34: 30: 26: 21: 663:female gonad development 442:tendon of biceps brachii 1230:10.1186/1749-8104-4-21 683:neuron differentiation 648:male gonad development 1088:transcription factors 504:medial dorsal nucleus 446:right coronary artery 287:Chromosome 1 (mouse) 185:Chromosome 1 (human) 62:List of PDB id codes 35:Available structures 668:gonad morphogenesis 512:inferior colliculus 492:coelomic epithelium 434:ganglionic eminence 414:germinal epithelium 1284:This article on a 1261:, which is in the 818:ENSMUSG00000019230 636:Biological process 620:Cellular component 574:Molecular function 450:buccal mucosa cell 1305: 1304: 1061: 1060: 1057: 1056: 1030: 1029: 995: 994: 966: 965: 932: 931: 903: 902: 869: 868: 850: 849: 824: 823: 805: 804: 779: 778: 760: 759: 708: 707: 601:metal ion binding 558: 557: 554: 553: 532: 531: 519: 518: 457: 456: 355: 354: 254: 253: 81: 80: 77: 76: 45:Ortholog search: 1355: 1326: 1319: 1312: 1280: 1273: 1252: 1242: 1232: 1198: 1197: 1190: 1184: 1183: 1172: 1166: 1165: 1154: 1148: 1138: 1127: 1117: 1096:gonadal agenesis 1043: 1042: 1014: 1007: 990: 970: 961: 941: 937:RefSeq (protein) 927: 907: 898: 878: 854: 835: 809: 790: 764: 745: 714: 564: 543: 528: 468: 466:Top expressed in 461: 406: 404:Top expressed in 399: 378: 361: 351: 338: 327: 312: 305: 299: 288: 276: 260: 250: 237: 226: 211: 204: 198: 187: 173: 157: 151: 149:LHX9 - orthologs 103:, LIM homeobox 9 102: 95: 72: 59: 53: 32: 31: 19: 1363: 1362: 1358: 1357: 1356: 1354: 1353: 1352: 1333: 1332: 1331: 1330: 1269: 1210: 1207: 1205:Further reading 1202: 1201: 1192: 1191: 1187: 1174: 1173: 1169: 1156: 1155: 1151: 1139: 1130: 1118: 1109: 1104: 1080: 1052:View/Edit Mouse 1047:View/Edit Human 1010: 1003: 1000:Location (UCSC) 986: 982: 978: 957: 953: 949: 923: 919: 915: 894: 890: 886: 799:ENSG00000143355 692: 631: 615: 591:protein binding 524: 515: 510: 506: 502: 498: 494: 490: 486: 482: 478: 464: 453: 448: 444: 440: 436: 432: 428: 424: 420: 416: 402: 346: 333: 325: 315: 314: 313: 306: 286: 263:Gene location ( 245: 232: 224: 214: 213: 212: 205: 183: 160:Gene location ( 111: 98: 91: 68: 46: 17: 12: 11: 5: 1361: 1359: 1351: 1350: 1345: 1335: 1334: 1329: 1328: 1321: 1314: 1306: 1303: 1302: 1281: 1254: 1253: 1206: 1203: 1200: 1199: 1185: 1167: 1149: 1128: 1106: 1105: 1103: 1100: 1079: 1076: 1064:LIM homeobox 9 1059: 1058: 1055: 1054: 1049: 1039: 1038: 1032: 1031: 1028: 1027: 1025: 1023: 1016: 1015: 1008: 1001: 997: 996: 993: 992: 974: 973: 967: 964: 963: 945: 944: 938: 934: 933: 930: 929: 911: 910: 904: 901: 900: 882: 881: 875: 871: 870: 867: 866: 858: 857: 851: 848: 847: 839: 838: 832: 826: 825: 822: 821: 813: 812: 806: 803: 802: 794: 793: 787: 781: 780: 777: 776: 768: 767: 761: 758: 757: 749: 748: 742: 736: 735: 730: 725: 721: 720: 710: 709: 706: 705: 694: 693: 691: 690: 685: 680: 675: 670: 665: 660: 655: 650: 645: 639: 637: 633: 632: 630: 629: 623: 621: 617: 616: 614: 613: 608: 603: 598: 593: 588: 583: 577: 575: 571: 570: 560: 559: 556: 555: 552: 551: 548: 547: 540: 534: 533: 530: 529: 521: 520: 517: 516: 514: 513: 509: 505: 501: 500:abdominal wall 497: 493: 489: 485: 481: 477: 473: 470: 469: 458: 455: 454: 452: 451: 447: 443: 439: 435: 431: 427: 423: 419: 415: 411: 408: 407: 395: 394: 386: 375: 369: 368: 365:RNA expression 357: 356: 353: 352: 344: 340: 339: 331: 328: 323: 317: 316: 307: 300: 294: 290: 289: 284: 278: 277: 269: 268: 256: 255: 252: 251: 243: 239: 238: 230: 227: 222: 216: 215: 206: 199: 193: 189: 188: 181: 175: 174: 166: 165: 153: 152: 109: 105: 104: 96: 88: 87: 83: 82: 79: 78: 75: 74: 64: 63: 55: 54: 43: 37: 36: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 1360: 1349: 1346: 1344: 1341: 1340: 1338: 1327: 1322: 1320: 1315: 1313: 1308: 1307: 1301: 1299: 1295: 1291: 1287: 1282: 1279: 1275: 1270: 1267: 1266: 1264: 1263:public domain 1260: 1250: 1246: 1241: 1236: 1231: 1226: 1222: 1218: 1214: 1209: 1208: 1204: 1195: 1189: 1186: 1181: 1177: 1171: 1168: 1163: 1159: 1153: 1150: 1146: 1142: 1137: 1135: 1133: 1129: 1125: 1121: 1116: 1114: 1112: 1108: 1101: 1099: 1097: 1093: 1089: 1085: 1077: 1075: 1073: 1069: 1065: 1053: 1048: 1044: 1040: 1037: 1033: 1026: 1024: 1021: 1017: 1013: 1009: 1006: 1002: 998: 991: 989: 985: 981: 975: 971: 968: 962: 960: 956: 952: 946: 942: 939: 935: 928: 926: 922: 918: 912: 908: 905: 899: 897: 893: 889: 883: 879: 876: 874:RefSeq (mRNA) 872: 865: 864: 859: 855: 852: 846: 845: 840: 836: 833: 831: 827: 820: 819: 814: 810: 807: 801: 800: 795: 791: 788: 786: 782: 775: 774: 769: 765: 762: 756: 755: 750: 746: 743: 741: 737: 734: 731: 729: 726: 722: 719: 715: 711: 704: 700: 695: 689: 686: 684: 681: 679: 676: 674: 671: 669: 666: 664: 661: 659: 656: 654: 651: 649: 646: 644: 641: 640: 638: 635: 634: 628: 625: 624: 622: 619: 618: 612: 609: 607: 604: 602: 599: 597: 594: 592: 589: 587: 584: 582: 579: 578: 576: 573: 572: 569: 568:Gene ontology 565: 561: 549: 544: 541: 539: 535: 527: 522: 511: 507: 503: 499: 495: 491: 487: 484:Gonadal ridge 483: 479: 475: 474: 471: 467: 462: 459: 449: 445: 441: 437: 433: 429: 425: 421: 417: 413: 412: 409: 405: 400: 397: 396: 393: 391: 387: 385: 384: 380: 379: 376: 374: 370: 366: 362: 358: 350: 345: 341: 337: 332: 322: 318: 311: 304: 298: 291: 283: 279: 275: 270: 266: 261: 257: 249: 244: 240: 236: 231: 221: 217: 210: 203: 197: 190: 186: 180: 176: 172: 167: 163: 158: 154: 150: 146: 142: 138: 134: 130: 126: 122: 118: 114: 106: 101: 94: 89: 84: 73: 71: 65: 60: 57: 56: 52: 49: 42: 38: 33: 29: 25: 20: 1298:expanding it 1290:chromosome 1 1283: 1268: 1256: 1255: 1220: 1216: 1188: 1179: 1170: 1161: 1152: 1084:LIM homeobox 1081: 1063: 1062: 984:NP_001036042 980:NP_001020736 977: 959:NP_001357142 951:NP_001014434 948: 921:NM_001042577 917:NM_001025565 914: 896:NM_001370213 888:NM_001014434 885: 861: 842: 816: 797: 771: 752: 732: 727: 496:pineal gland 388: 381: 347:138,848,577 334:138,825,186 246:197,935,478 233:197,911,902 108:External IDs 67: 1092:homeodomain 586:DNA binding 426:right ovary 326:1|1 E4 86:Identifiers 1337:Categories 1217:Neural Dev 1147:, May 2017 1126:, May 2017 1102:References 422:left ovary 392:(ortholog) 129:HomoloGene 1288:on human 988:NP_034844 955:NP_064589 925:NM_010714 892:NM_020204 718:Orthologs 137:GeneCards 1249:19545367 1143:– 1122:– 1078:Function 1036:Wikidata 697:Sources: 480:habenula 418:testicle 1240:2704203 1145:Ensembl 1124:Ensembl 1068:protein 830:UniProt 785:Ensembl 724:Species 703:QuickGO 627:nucleus 367:pattern 125:1316721 93:Aliases 1247:  1237:  1223:: 21. 1022:search 1020:PubMed 863:Q9WUH2 844:Q9NQ69 740:Entrez 538:BioGPS 225:1q31.3 117:606066 1292:is a 1066:is a 773:16876 754:56956 733:Mouse 728:Human 699:Amigo 488:fossa 438:gonad 390:Mouse 383:Human 330:Start 265:Mouse 229:Start 162:Human 1294:stub 1286:gene 1245:PMID 1072:gene 508:foot 476:hand 373:Bgee 321:Band 282:Chr. 220:Band 179:Chr. 141:LHX9 133:7816 113:OMIM 100:LHX9 70:2DMQ 51:RCSB 48:PDBe 22:LHX9 1235:PMC 1225:doi 546:n/a 343:End 242:End 145:OMA 121:MGI 41:PDB 1339:: 1243:. 1233:. 1219:. 1215:. 1178:. 1160:. 1131:^ 1110:^ 1074:. 701:/ 349:bp 336:bp 248:bp 235:bp 143:; 139:: 135:; 131:: 127:; 123:: 119:; 115:: 1325:e 1318:t 1311:v 1300:. 1265:. 1251:. 1227:: 1221:4 1196:. 1182:. 1164:. 267:) 164:) 147::

Index

PDB
PDBe
RCSB
2DMQ
Aliases
LHX9
OMIM
606066
MGI
1316721
HomoloGene
7816
GeneCards
LHX9
OMA
LHX9 - orthologs
Human
Chromosome 1 (human)
Chr.
Chromosome 1 (human)
Chromosome 1 (human)
Genomic location for LHX9
Genomic location for LHX9
Band
bp
bp
Mouse
Chromosome 1 (mouse)
Chr.
Chromosome 1 (mouse)

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