103:
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62:
176:
healed and are then removed. The temporary implants take most of the burden off of the fracture, causing the bone to become less dense. This can lead to re-fracturing of the bone after the implant is removed. The implants can also cause stress concentrations as a result of the material difference between the bone and the plate. With the permanent prostheses, a putty-like substance is injected into the implant site to keep the body, mainly the
295:
playing sports and avoid undergoing additional surgeries throughout their lives. Rotationplasty is also durable and has been associated with enhanced quality of life and life contentment. Unfortunately, not every case turns out favorably. Rotationplasty can result in problems with blood supply to the leg, infection, nerve injuries, problems with bone healing, and fracture of the leg.
239:, more commonly known as Van-Nes or Borggreve Rotation, is a limb-sparing medical procedure performed when a patient's leg is amputated at the knee. The ankle joint is then rotated 180 degrees and is attached to the former knee joint, becoming a new knee joint. This allows patients to have two fully functional feet, as opposed to losing one leg completely to amputation.
53:, which has been associated with a lower 5-year survival rate and cost-effectiveness compared to limb salvage in the long-run. There are many different types of limb-sparing techniques, including arthrodesis, arthroplasty, endoprosthetic reconstruction, various types of implants, rotationplasty, osseointegration limb replacement, fasciotomy, and revascularization.
272:
Rotationplasty was first performed by
Borggreve in the early 1900s on a 12-year-old boy with tuberculosis. However, the procedure was not well known until 1950. At that time, physician Van Nes reported the results of rotationplasty procedures and became well known for founding the procedure. Since
175:
are used when sections of bone must be replaced and no further growth is expected. Implants are mostly made from metals, but the possibility of using ceramic material has been discussed among surgeons. Prosthetics can be temporary or permanent. Temporary implants remain in place until the bone has
294:
In the same scenario, amputation would not leave a knee joint. Rotationplasty retains the use of a knee joint. Furthermore, it provides a better position for a prosthetic limb compared to amputation. As a result, children who have had rotationplasty can return to their previous activities such as
285:
bone, is removed. The ankle joint is then turned 180 degrees and is reattached to the thigh. They are held together by plates and screws until they have healed naturally. The surgery can take anywhere from 6–10 hours, with a day or two in intensive care. The leg is kept in a cast for 6–12 weeks.
1164:
Costanzo, Roberta; Ferini, Gianluca; Brunasso, Lara; Bonosi, Lapo; Porzio, Massimiliano; Benigno, Umberto
Emanuele; Musso, Sofia; Gerardi, Rosa Maria; Giammalva, Giuseppe Roberto; Paolini, Federica; Palmisciano, Paolo; Umana, Giuseppe Emmanuele; Sturiale, Carmelo Lucio; Di Bonaventura, Rina;
1578:
33:, also known as limb-saving or limb-salvage techniques, are performed in order to preserve the look and function of limbs. Limb-sparing techniques are used to preserve limbs affected by trauma, arthritis, cancers such as high-grade
1472:
Ramseier, Leonhard E.; Dumont, Charles E.; Ulrich Exner, G. (2008). "Rotationplasty (Borggreve/Van Nes and modifications) as an alternative to amputation in failed reconstructions after resection of tumours around the knee joint".
251:
of the knee. While it is still being used to treat their complications, rotationplasty is also used to treat growing children who have been diagnosed with tumors around the knee. Rotationplasty is also performed on children with
93:
are bone grafts from other bones in a patient's body. Patient-reported outcomes following this procedure are typically positive in terms of long-term pain relief; however, the procedure also results in decreased range of motion.
68:. In this case, this means that screws have been inserted through multiple wrist bones so they are now immobilized. Over time, these bones will fuse together, preventing them from rubbing against each other and causing pain.
205:
leverages the power of computer rendering of advanced imaging to tailor implants to each patient, which can then be used to create a physical realization of that implant to use in that individual's surgery. 3D-printing of
118:, otherwise known as joint replacement, is a surgical procedure which involves resurfacing, realignment, or removal of bone at a joint interface to restore the joint's function. Arthroplasty is often performed on
190:
Notice the use of the advanced computer software to create a 3-dimensional rendering of the part of the skull that will be printed. The rightmost photo depicts the 3D-printed implant placed on the actual
162:" using arthroplasty techniques, and then prosthesis is used to support and strengthen the allografts. Alloprosthetic composites are flexible in that surgeons can adapt the implants for any situation.
77:
is the surgical immobilization of bones within a joint to promote fusion of the joint. Arthrodesis is performed most commonly on joints of the feet, hands, and spine. Arthrodesis can relieve pain from
134:
to improve range of motion and relieve pain from arthritis or trauma. Arthroplasty of the shoulder is one of the most common of these procedures, although it has only been widely used since 1955.
1413:
Gaillard, Jean; Fouasson-Chailloux, Alban; Eveno, Dominique; Bokobza, Guillaume; Da Costa, Marta; Heidar, Romain; Pouedras, Marie; Nich, Christophe; Gouin, François; Crenn, Vincent (2022).
102:
637:"Clinical Outcomes of Total Ankle Arthroplasty Versus Ankle Arthrodesis for the Treatment of End-Stage Ankle Arthritis in the Last Decade: a Systematic Review and Meta-analysis"
180:, from fighting off the implant. This substance can deteriorate bony tissue and cause serious bone problems for the patient. Prosthetic limbs have been used for many years.
1232:
Papotto, Giacomo; Testa, Gianluca; Mobilia, Giuseppe; Perez, Stefano; Dimartino, Sara; Giardina, Serena Maria Chiara; Sessa, Giuseppe; Pavone, Vito (2021-10-11).
1757:
Hillmann, A.; Gosheger, G.; Hoffmann, C.; Ozaki, T.; Winkelmann, W. (2000). "Rotationplasty - surgical treatment modality after failed limb salvage procedure".
894:"Total hip arthroplasty for posttraumatic osteoarthritis following acetabular fracture: A systematic review of characteristics, outcomes, and complications"
1415:"Rotationplasty Salvage Procedure as an Effective Alternative to Femoral Amputation in an Adult With a History of Osteosarcoma: A Case Report and Review"
109:
Notice that the articular surface of each joint has been removed and replaced with metal and plastic implants to recreate the normal joint interface.
1109:"3D-printed spine surgery implants: a systematic review of the efficacy and clinical safety profile of patient-specific and off-the-shelf devices"
158:
are a combination of multiple limb-sparing techniques, namely allografts and prosthesis. Allografts are used to replace the bone that has been "
411:
138:
is thought to have created the first shoulder arthroplasty in the 1800s. Since Gluck never published any results or notes on the procedure,
1805:
1632:
750:
Fadhel, Wael Ben; Taieb, Léa; Villain, Benoît; Mebtouche, Nasser; Levante, Stéphane; Bégué, Thierry; Aurégan, Jean-Charles (2022-02-05).
752:"Outcomes after primary ankle arthrodesis in recent fractures of the distal end of the tibia in the elderly: a systematic review"
1534:
Brown, Kenneth L.B. (2001). "Resection, Rotationplasty, and
Femoropelvic Arthrodesis in Severe Congenital Femoral Deficiency".
521:"Posterior Arthrodesis of Atlantoaxial Joint in Congenital Atlantoaxial Instability Under 5 Years of Age: A Systematic Review"
311:
1520:
Soni, Emily. "A Surgeon's
Approach – The Dynamics of Rotationplasty." Rotationplasty. N.p., 2011. Web. 19 Oct 2011. <
281:
In the actual procedure, the bone affected by the tumor, as well as a small part of the healthy femur and occasionally
1521:
1388:
1234:"Use of 3D printing and pre-contouring plate in the surgical planning of acetabular fractures: A systematic review"
1167:"The Role of 3D-Printed Custom-Made Vertebral Body Implants in the Treatment of Spinal Tumors: A Systematic Review"
892:
Stibolt, Robert; Patel, Harshadkumar; Huntley, Samuel; Lehtonen, Eva; Shah, Ashish; Naranje, Sameer (2018-04-26).
260:. This procedure gives patients the ability to retain the use of both feet, allowing them to continue living an
183:
107:
Diagrams of the most common joints that undergo arthroplasty (joint replacement): shoulders, hips, and knees.
519:
Goyal, Nikhil; Bali, Shivkumar; Ahuja, Kaustubh; Chaudhary, Sunny; Barik, Sitanshu; Kandwal, Pankaj (2021).
1107:
Burnard, Joshua L.; Parr, William C. H.; Choy, Wen Jie; Walsh, William R.; Mobbs, Ralph J. (2020-06-01).
399:
139:
1708:
Rödl, Robert W.; Pohlmann, Ursula; Gosheger, Georg; Lindner, Norbert J.; Winkelmann, Winfried (2002).
1178:
731:. VA Evidence-based Synthesis Program Reports. Washington (DC): Department of Veterans Affairs (US).
256:
femoral deficiencies, such as those that cause unstable hip joints or limb-length discrepancy of the
127:
247:
Originally, rotationplasty was performed to treat infections and tumors around the knee, especially
49:, and diagnostic modalities improve, there has been a trend toward limb-sparing procedures to avoid
273:
then, many surgeons have performed modified versions of rotationplasty and have had great success.
159:
90:
86:
61:
38:
578:
Faulkner, Harrison; An, Vincent; Lawson, Richard; Graham, David; Sivakumar, Brahman (2021-03-07).
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Kauvar, David S.; Propper, Brandon W. (2022-01-01), Rasmussen, Todd E.; Tai, Nigel R. M. (eds.),
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Shah, Nihar S.; Umeda, Yuta; Suriel
Peguero, Emil; Erwin, Jace T.; Laughlin, Richard (2021).
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1060:"Alloprosthetic Composite is a Suitable Reconstruction After Periacetabular Tumor Resection"
1058:
Donati, Davide; Di Bella, Claudia; Frisoni, Tommaso; Cevolani, Luca; Degroot, Henry (2011).
1016:
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763:
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607:
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123:
85:. This is accomplished through the use of orthobiologics such as allografts and autografts.
223:
219:
119:
188:
Diagram of workflow describing the basic process of 3D-printing an implant for the skull.
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520:
434:"Amputation Versus Limb-Salvage Surgery in Patients with Osteosarcoma: A Meta-analysis"
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Bernthal, Nicholas; Monument, Michael; Randall, R. Lor; Jones, Kevin (2014-06-01).
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253:
248:
114:
42:
34:
1330:
Wallace, Nicholas; Schaffer, Nathaniel; Aleem, Ilyas; Patel, Rakesh (2020-12-01).
66:
X-ray of a wrist that has undergone carpal arthrodesis (fusion of the wrist joint)
1522:
http://www.rotationplasty.org/A-Surgeons-Approach--The-Dynamics-of-Rotationplasty
1347:
909:
200:
73:
1726:
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1125:
1108:
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Janssen, Stein; Langerhuizen, David; Schwab, Joseph; Bramer, Jos (2019-07-07).
854:
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After the leg has sufficiently healed, the leg can be fitted for a prosthetic.
1676:
1579:"Kniegelenksersatz durch das in der Beinlängsachse um 180° gedrehte Fußgelenk"
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1431:
1075:
1005:"Outcome after reconstruction of proximal femoral tumors: A systematic review"
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357:
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1004:
838:
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636:
580:"Proximal Interphalangeal Joint Arthrodesis Techniques: A Systematic Review"
433:
78:
17:
1778:
1735:
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Scandinavian
Journal of Plastic and Reconstructive Surgery and Hand Surgery
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10.1002/(SICI)1098-2388(199701/02)13:1<34::AID-SSU6>3.0.CO;2-5
1191:
725:
Greer, Nancy; Yoon, Patrick; Majeski, Brittany; Wilt, Timothy J. (2020).
432:
Han, Gang; Bi, Wen-Zhi; Xu, Meng; Jia, Jin-Peng; Wang, Yan (2016-04-26).
82:
1594:
728:
Orthobiologics in Foot and Ankle
Arthrodesis Sites: A Systematic Review
1020:
142:
is credited with performing the first shoulder arthroplasty in 1893.
839:"Outcome Reporting in Total Ankle Arthroplasty: A Systematic Review"
282:
257:
101:
1332:"3D-printed Patient-specific Spine Implants: A Systematic Review"
89:
are done by creating bone grafts from a donor bone bank, whereas
215:
1710:"Rotationplasty--quality of life after 10 years in 22 patients"
214:
and custom prosthetics but has since been used for various
1295:
The
Bulletin of the Royal College of Surgeons of England
635:
Shih, Chia-Lung; Chen, Shu-Jung; Huang, Peng-Ju (2020).
1238:
Orthopaedics & Traumatology, Surgery & Research
1661:"Rotationplasty: Beauty is in the Eye of the Beholder"
1536:
The
Journal of Bone and Joint Surgery-American Volume
956:"A History of Reverse Total Shoulder Arthroplasty"
813:, Treasure Island (FL): StatPearls Publishing,
698:, Treasure Island (FL): StatPearls Publishing,
495:, Treasure Island (FL): StatPearls Publishing,
290:Advantages and disadvantages of rotationplasty
1583:Archiv für Orthopädische und Unfall-Chirurgie
954:Flatow, Evan L.; Harrison, Alicia K. (2011).
8:
1064:Clinical Orthopaedics & Related Research
960:Clinical Orthopaedics & Related Research
487:Chambers, Aaron R.; Dreyer, Mark A. (2022),
406:, Philadelphia: Elsevier, pp. 273–287,
690:Jimenez, Andreea; Anand, Prashanth (2022),
1759:Archives of Orthopaedic and Trauma Surgery
1291:"The history of 3D printing in healthcare"
1725:
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1165:Iacopino, Domenico Gerardo (2022-03-28).
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1619:Kotz, Rainer (1997). "Rotationplasty".
1614:
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1514:
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404:Rich's Vascular Trauma (Fourth Edition)
303:
400:"22 - Lower Extremity Vascular Trauma"
1654:
1652:
1650:
1383:
1381:
843:The Journal of Foot and Ankle Surgery
805:Hsu, Hunter; Siwiec, Ryan M. (2022),
720:
718:
641:The Journal of Foot and Ankle Surgery
7:
1665:Operative Techniques in Orthopaedics
334:
332:
312:"Definition of limb-sparing surgery"
525:Journal of Pediatric Neurosciences
37:, and vascular conditions such as
25:
345:Indian Journal of Plastic Surgery
1548:10.2106/00004623-200101000-00011
1308:10.1308/147363514X13990346756481
1289:Whitaker, Matthew (2015-06-12).
210:was first used in the 1990s for
898:Chinese Journal of Traumatology
1714:Acta Orthopaedica Scandinavica
1393:NCI Dictionary of Cancer Terms
1389:"Definition of rotationplasty"
316:NCI Dictionary of Cancer Terms
1:
1621:Seminars in Surgical Oncology
1348:10.1097/BSD.0000000000001026
1009:Journal of Surgical Oncology
1806:Surgical removal procedures
1605:– via Google Scholar.
1577:Borggreve, J (1930-01-01).
910:10.1016/j.cjtee.2018.02.004
1822:
1727:10.1080/000164702317281468
1251:10.1016/j.otsr.2021.103111
1126:10.1007/s00586-019-06236-2
855:10.1053/j.jfas.2021.02.003
768:10.1007/s00264-022-05317-0
756:International Orthopaedics
653:10.1053/j.jfas.2019.10.008
339:Kadam, Dinesh (May 2013).
243:Reasons for rotationplasty
1677:10.1053/j.oto.2013.11.001
1487:10.1080/02844310802069434
1432:10.3389/fsurg.2021.820019
1076:10.1007/s11999-011-1799-9
972:10.1007/s11999-010-1733-6
450:10.1007/s00268-016-3500-7
268:History of rotationplasty
156:Alloprosthetic composites
151:Alloprosthetic composites
596:10.1177/1558944721998019
438:World Journal of Surgery
358:10.4103/0970-0358.118603
277:Rotationplasty procedure
41:. As the techniques for
31:Limb-sparing techniques
1336:Clinical Spine Surgery
1113:European Spine Journal
538:10.4103/jpn.JPN_270_20
341:"Limb salvage surgery"
192:
110:
69:
1771:10.1007/s004020000175
186:
105:
64:
1419:Frontiers in Surgery
1192:10.3390/life12040489
489:"Triple Arthrodesis"
39:diabetic foot ulcers
1183:2022Life...12..489C
807:"Knee Arthroplasty"
692:"Wrist Arthrodesis"
196:3D-printed implants
172:Prosthetic implants
166:Prosthetic implants
1595:10.1007/BF02581614
193:
136:Themistocles Gluck
111:
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1021:10.1002/jso.25297
413:978-0-323-69766-8
27:Medical procedure
16:(Redirected from
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1395:. 2011-02-02
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320:. Retrieved
318:. 2011-02-02
315:
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249:osteosarcoma
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115:Arthroplasty
113:
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106:
98:Arthroplasty
72:
71:
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43:chemotherapy
30:
29:
18:Limb salvage
1589:: 175–178.
202:3D-printing
74:Arthrodesis
57:Arthrodesis
1425:: 820019.
1399:2023-01-24
1177:(4): 489.
824:2023-01-18
811:StatPearls
709:2023-01-17
696:StatPearls
506:2023-01-17
493:StatPearls
419:2023-01-13
322:2023-01-17
299:References
254:congenital
91:autografts
87:Allografts
51:amputation
1441:2296-875X
1372:219926586
1356:2380-0194
1317:1473-6357
1276:238990983
1260:1877-0568
1201:2075-1729
1151:208539337
1135:1432-0932
1029:1096-9098
918:1008-1275
879:232367188
863:1542-2224
792:246534323
776:1432-5195
677:225584427
661:1542-2224
604:1558-9455
547:1817-1745
458:1432-2323
367:0970-0358
128:shoulders
83:fractures
79:arthritis
47:radiation
1800:Category
1779:11110135
1744:30887593
1736:11928918
1695:25414567
1603:40801977
1564:23701234
1556:11205862
1503:10486883
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622:33682483
565:35018176
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466:27116252
385:24501463
222:such as
160:resected
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283:tibia
258:femur
216:bones
124:knees
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