461:
45:
36:
3134:
1438:
1431:
1872:
838:. It carbamylates about 30% of peripheral cholinesterase enzyme, and the carbamylated enzyme eventually regenerates by natural hydrolysis and excess acetylcholine (ACh) levels revert to normal.
1918:
1424:
1317:
Kanjwal K, Karabin B, Sheikh M, Elmer L, Kanjwal Y, Saeed B, Grubb BP (June 2011). "Pyridostigmine in the treatment of postural orthostatic tachycardia: a single-center experience".
3179:
845:(Na,) resulting in depolarization. If large enough, this depolarization results in an action potential. To prevent constant stimulation once the ACh is released, an enzyme called
3106:
159:
3111:
741:
Pyridostigmine bromide is contraindicated in cases of mechanical intestinal or urinary obstruction and should be used with caution in patients with bronchial asthma.
688:
drug toxicity. Pyridostigmine bromide has been FDA approved for military use during combat situations as an agent to be given prior to exposure to the nerve agent
67:
548:
726:
3154:
2063:
1533:
3169:
858:
661:
2985:
2898:
1021:
2954:
1758:
982:
1015:
898:
615:
568:
1543:
3164:
2038:
534:
278:
189:
1577:
804:
681:
642:
148:
1503:
3174:
2253:
3124:
1553:
3159:
3101:
2840:
1454:
1069:
380:
1538:
629:
Common side effects include nausea, diarrhea, frequent urination, and abdominal pain. More severe side effects include
2048:
849:
is present in the endplate membrane close to the receptors on the post synaptic membrane, and quickly hydrolyses ACh.
841:
The ACh diffuses across the synaptic cleft and binds to receptors on the post synaptic membrane, causing an influx of
440:
730:
1548:
1385:
1182:
915:
2733:
2711:
1183:"The effectiveness of parasympathomimetics for treating underactive bladder: A systematic review and meta-analysis"
916:"The effectiveness of parasympathomimetics for treating underactive bladder: A systematic review and meta-analysis"
1513:
1498:
1482:
1035:
878:
1518:
1063:
2928:
2581:
2478:
2203:
704:
152:
835:
1508:
711:
125:
626:
but can also be used by injection. The effects generally begin within 45 minutes and last up to 4 hours.
2846:
2767:
3011:
3007:
3003:
2999:
2976:
2972:
429:
1367:
2696:
2043:
1563:
1523:
1106:
846:
811:
650:
245:
1416:
456:
2857:
2823:
2757:
2686:
2503:
2453:
1978:
1778:
1636:
623:
295:
136:
132:
2563:
2559:
2555:
2551:
1788:
1745:
1696:
1274:
Gales BJ, Gales MA (February 2007). "Pyridostigmine in the treatment of orthostatic intolerance".
1228:
Gales BJ, Gales MA (February 2007). "Pyridostigmine in the treatment of orthostatic intolerance".
2574:
2278:
2173:
1750:
1616:
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1210:
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665:
634:
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99:
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44:
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1005:
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217:
204:
77:
57:
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1721:
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3041:
2737:
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2523:
2518:
2513:
2508:
2428:
2313:
2193:
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2013:
1471:
1326:
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1237:
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1132:
1114:
1043:
927:
886:
808:
619:
477:
227:
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978:
389:
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1968:
1958:
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1389:
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369:
235:
304:
1110:
460:
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2208:
1963:
1933:
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1094:
815:
715:
1181:
Moro C, Phelps C, Veer V, Clark J, Glasziou P, Tikkinen KA, Scott AM (November 2021).
914:
Moro C, Phelps C, Veer V, Clark J, Glasziou P, Tikkinen KA, Scott AM (November 2021).
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1330:
1214:
947:
823:
722:
654:
91:
20:
1346:
1303:
1257:
660:
Pyridostigmine was patented in 1945 and came into medical use in 1955. It is on the
3022:
2813:
2706:
2661:
2626:
2616:
2611:
2458:
2338:
2243:
2148:
1973:
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167:
329:
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1988:
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1822:
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1626:
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827:
646:
85:
1099:
Proceedings of the
National Academy of Sciences of the United States of America
27:
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2028:
1998:
1862:
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1706:
1671:
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1621:
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1450:
819:
510:
360:
143:
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2413:
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2003:
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1983:
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1943:
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1807:
1736:
1711:
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1591:
1119:
831:
638:
258:
71:
35:
1338:
1295:
1249:
1206:
1146:
1040:
World Health
Organization model list of essential medicines: 21st list 2019
939:
1382:
3081:
2783:
2716:
2671:
2601:
2569:
2468:
2448:
2438:
2303:
2223:
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2018:
1923:
1857:
1802:
1726:
1676:
1606:
1586:
693:
611:
340:
1128:
1048:
349:
2818:
2726:
2691:
2463:
2363:
2333:
2318:
2268:
2163:
2108:
2103:
2098:
2093:
2088:
2083:
2078:
2053:
2008:
1902:
1897:
1817:
1812:
1686:
1166:
890:
315:
1287:
1241:
1198:
931:
2343:
2133:
1892:
1887:
1882:
1877:
1691:
1465:
842:
685:
420:
263:
857:
Pyridostigmine bromide is available under the trade name
Mestinon (
696:, pyridostigmine bromide has been implicated as a causal factor in
692:
in order to increase survival. Used in particular during the first
576:
InChI=1S/C9H13N2O2/c1-10(2)9(12)13-8-5-4-6-11(3)7-8/h4-7H,1-3H3/q+1
409:
2721:
2443:
2433:
2283:
2178:
1528:
689:
533:
524:
400:
198:
1420:
676:
Pyridostigmine is used to treat muscle weakness in people with
211:
1873:
Octamethylene-bis(5-dimethylcarbamoxyisoquinolinium bromide)
445:
2986:
2899:
1919:
2-Ethoxycarbonyl-1-methylvinyl cyclohexyl methylphosphonate
110:
2955:
1364:
649:
family of medications. It works by blocking the action of
1383:
Mestinon
Official FDA information, side effects and uses
1095:"Acetylcholinesterase inhibitors and Gulf War illnesses"
1052:. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
662:
610:
and underactive bladder. It is also used together with
593:
3122:
981:. The American Society of Health-System Pharmacists.
1162:"Gulf War illness linked to chemical exposure-study"
834:
inhibitor of cholinesterase that does not cross the
3040:
2944:
2927:
2897:
2856:
2839:
2766:
1562:
1481:
1464:
522:
509:
476:
471:
439:
419:
399:
379:
359:
339:
314:
294:
269:
257:
244:
234:
226:
188:
183:
158:
142:
124:
98:
84:
66:
56:
51:
1483:
1360:
1358:
1356:
328:
1269:
1267:
881:(2009). Stuart MC, Kouimtzi M, Hill SR (eds.).
729:(POTS) as well as complications resulting from
707:, it can be used to treat underactive bladder.
303:
2828:Many of the other AChE inhibitors listed above
714:. It may also be of benefit in chronic axonal
3180:World Health Organization essential medicines
2768:
1432:
8:
3107:Muscarinic acetylcholine receptor modulators
1564:
703:With pyridostigmine classified as a type of
641:is safe for the fetus. Pyridostigmine is an
26:
3112:Nicotinic acetylcholine receptor modulators
2991:Tooltip Vesicle-associated membrane protein
2904:Tooltip Vesicular acetylcholine transporter
2858:
2960:Tooltip Synaptosomal-associated protein 25
2941:
2853:
1478:
1439:
1425:
1417:
973:
971:
969:
967:
965:
963:
961:
959:
957:
885:. World Health Organization. p. 429.
710:Pyridostigmine sometimes is used to treat
459:
368:
43:
34:
16:Medication used to treat myasthenia gravis
1136:
1118:
1047:
727:postural orthostatic tachycardia syndrome
388:
3129:
2064:Dimethyl 4-(methylthio)phenyl phosphate
1064:"Competitive Generic Therapy Approvals"
870:
573:
553:
455:
348:
283:
90:
1010:. John Wiley & Sons. p. 540.
861:), Regonol and Gravitor (SUN Pharma).
653:and therefore increases the levels of
25:
2254:Methylfluorophosphonylcholine (MFPCh)
1504:2-(α-Naphthoyl)ethyltrimethylammonium
1319:Pacing and Clinical Electrophysiology
1160:Steenhuysen, Julie (March 10, 2008).
1042:. Geneva: World Health Organization.
985:from the original on 21 December 2016
428:
76:
7:
1412:. U.S. National Library of Medicine.
171:
3051:
1554:N,N-Dimethylaminoethylchloroacetate
780:Facial flushing due to vasodilation
664:. Pyridostigmine is available as a
408:
319:
14:
1488:Tooltip Choline acetyltransferase
787:Additional side effects include:
616:neuromuscular blocking medication
3132:
2548:Fasciculins (green mamba toxins)
2039:Dicyclohexyl phosphorofluoridate
1331:10.1111/j.1540-8159.2011.03047.x
1024:from the original on 2016-12-20.
494:
488:
3155:Acetylcholinesterase inhibitors
2479:Tetraethyl pyrophosphate (TEPP)
2204:Hexaethyl tetraphosphate (HETP)
1004:Fischer J, Ganellin CR (2006).
581:Key:RVOLLAQWKVFTGE-UHFFFAOYSA-N
1549:N,N-Dimethylaminoethylacrylate
805:acetylcholinesterase inhibitor
774:Increased bronchial secretions
682:congenital myasthenic syndrome
643:acetylcholinesterase inhibitor
606:is a medication used to treat
500:
482:
149:Acetylcholinesterase inhibitor
1:
3102:Receptor/signaling modulators
2874:Hemicholinium-3 (hemicholine)
2773:Tooltip Butyrylcholinesterase
1276:The Annals of Pharmacotherapy
1230:The Annals of Pharmacotherapy
1007:Analogue-based Drug Discovery
749:Common side effects include:
684:and to combat the effects of
3170:Peripherally selective drugs
1569:Tooltip Acetylcholinesterase
1187:Neurourology and Urodynamics
1070:Food and Drug Administration
920:Neurourology and Urodynamics
721:It is also being prescribed
622:type. It is typically given
2863:Tooltip Choline transporter
2809:Profenamine (ethopropazine)
2049:Diisopropyl fluorophosphate
1514:4-(1-Naphthylvinyl)pyridine
1499:1-(-Benzoylethyl)pyridinium
3196:
2712:Dimethylcarbamoyl fluoride
1519:Acetylseco hemicholinium-3
794:Muscle cramps and weakness
637:. It is unclear if use in
472:Chemical and physical data
18:
3094:
1036:World Health Organization
879:World Health Organization
589:
564:
544:
274:
42:
33:
2582:Methanesulfonyl fluoride
1093:Golomb BA (March 2008).
883:WHO Model Formulary 2008
818:, thus slowing down the
19:Not to be confused with
3165:Dimethylamino compounds
1759:+glycopyrronium bromide
1410:Drug Information Portal
1120:10.1073/pnas.0711986105
859:Valeant Pharmaceuticals
826:. Like its predecessor
712:orthostatic hypotension
1509:3-Chloro-4-stillbazole
731:Ehlers–Danlos syndrome
614:to end the effects of
979:"Neostigmine Bromide"
830:, it is a quaternary
803:Pyridostigmine is an
556:O=C(Oc1ccc(c1)C)N(C)C
286:3--1-methylpyridinium
3175:Pyridinium compounds
3070:Atracotoxins (e.g.,
2697:Tetrahydrocannabinol
2044:Diisopropylphosphate
847:acetylcholinesterase
812:acetylcholinesterase
783:Erectile dysfunction
768:Increased salivation
651:acetylcholinesterase
3160:Aromatic carbamates
3056:Tooltip Latrophilin
2758:Trimedoxime bromide
2687:Stercuronium iodide
2504:Tricresyl phosphate
1979:Chlorpyrifos-methyl
1111:2008PNAS..105.4295G
836:blood–brain barrier
799:Mechanism of action
705:parasympathomimetic
207:(Prescription only)
153:Parasympathomimetic
30:
2575:Onchidella binneyi
1917:Organophosphates:
1388:2008-05-24 at the
1370:2008-05-13 at the
777:Constricted pupils
666:generic medication
635:allergic reactions
631:low blood pressure
3120:
3119:
3090:
3089:
2938:
2923:
2922:
2850:
2835:
2834:
2474:Tetrachlorvinphos
2349:Pirimiphos-methyl
2299:Oxydemeton-methyl
2249:Methyl phenkapton
1475:
1288:10.1345/aph.1H458
1242:10.1345/aph.1H458
1199:10.1002/nau.24839
1105:(11): 4295–4300.
932:10.1002/nau.24839
737:Contraindications
698:Gulf War syndrome
678:myasthenia gravis
608:myasthenia gravis
601:
600:
535:Interactive image
441:CompTox Dashboard
253:1.78 ± 0.24 hours
215:
202:
114:
3187:
3137:
3136:
3135:
3128:
3057:
3053:
2992:
2988:
2961:
2957:
2942:
2932:
2905:
2901:
2864:
2860:
2854:
2844:
2774:
2770:
2738:Asoxime chloride
2314:Parathion-methyl
2014:Demeton-S-methyl
1570:
1566:
1489:
1485:
1479:
1469:
1441:
1434:
1427:
1418:
1413:
1406:"Pyridostigmine"
1392:
1380:
1374:
1362:
1351:
1350:
1314:
1308:
1307:
1271:
1262:
1261:
1225:
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1151:
1150:
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1090:
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1079:
1060:
1054:
1053:
1051:
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1026:
1025:
1001:
995:
994:
992:
990:
975:
952:
951:
911:
905:
904:
875:
791:Muscle twitching
765:Abdominal cramps
633:, weakness, and
620:non-depolarizing
597:
596:
537:
517:
502:
496:
490:
484:
464:
463:
449:
447:
432:
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332:
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321:
307:
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213:
210:
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175:
112:
109:
94:
80:
62:Mestinon, others
47:
38:
31:
29:
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3190:
3189:
3188:
3186:
3185:
3184:
3145:
3144:
3143:
3133:
3131:
3123:
3121:
3116:
3086:
3055:
3036:
2996:Botulinum toxin
2990:
2965:Botulinum toxin
2959:
2931:
2919:
2903:
2893:
2879:Triethylcholine
2862:
2843:
2831:
2772:
2762:
2682:Rosmarinic acid
2449:Sulfotep (TEDP)
2119:Ethylsarin (GE)
1999:Cyclosarin (GF)
1969:Chlorfenvinphos
1959:Carbophenothion
1939:Azinphos-methyl
1568:
1558:
1524:Acryloylcholine
1487:
1468:
1460:
1445:
1404:
1401:
1396:
1395:
1390:Wayback Machine
1381:
1377:
1372:Wayback Machine
1365:Mestinon | Home
1363:
1354:
1316:
1315:
1311:
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1222:
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236:Bioavailability
228:Pharmacokinetic
222:
179:
127:
120:
101:
24:
17:
12:
11:
5:
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3085:
3084:
3079:
3064:
3063:
3046:
3044:
3038:
3037:
3035:
3034:
3031:γ-bungarotoxin
3027:β-bungarotoxin
3016:
3015:
2981:
2980:
2950:
2948:
2939:
2925:
2924:
2921:
2920:
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2614:
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2341:
2336:
2331:
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2321:
2316:
2311:
2306:
2301:
2296:
2291:
2289:Novichok agent
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2276:
2271:
2266:
2261:
2256:
2251:
2246:
2241:
2236:
2231:
2226:
2221:
2216:
2211:
2209:Isofluorophate
2206:
2201:
2196:
2191:
2186:
2181:
2176:
2171:
2166:
2161:
2156:
2151:
2146:
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2036:
2031:
2026:
2021:
2016:
2011:
2006:
2001:
1996:
1991:
1986:
1981:
1976:
1971:
1966:
1964:Chlorethoxyfos
1961:
1956:
1951:
1946:
1941:
1936:
1934:Azinphos-ethyl
1931:
1926:
1921:
1911:
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1830:
1825:
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1815:
1810:
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1795:
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1776:
1774:Pyridostigmine
1771:
1766:
1761:
1753:
1748:
1743:
1734:
1729:
1724:
1719:
1714:
1709:
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1399:External links
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1016:
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604:Pyridostigmine
599:
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28:Pyridostigmine
15:
13:
10:
9:
6:
4:
3:
2:
3192:
3181:
3178:
3176:
3173:
3171:
3168:
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3126:
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3110:
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3083:
3080:
3077:
3073:
3069:
3066:
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3062:
3059:
3054:
3048:
3047:
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3043:
3039:
3032:
3028:
3024:
3023:Bungarotoxins
3021:
3018:
3017:
3013:
3009:
3005:
3001:
2997:
2994:
2993:inactivators:
2989:
2983:
2982:
2978:
2974:
2970:
2966:
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2962:inactivators:
2958:
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2869:
2868:
2866:
2861:
2855:
2852:
2848:
2842:
2838:
2827:
2825:
2824:ZINC-12613047
2822:
2820:
2817:
2815:
2812:
2810:
2807:
2805:
2802:
2800:
2797:
2795:
2792:
2790:
2787:
2785:
2782:
2779:
2778:
2776:
2771:
2765:
2759:
2756:
2754:
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2728:
2725:
2723:
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2718:
2715:
2713:
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2708:
2705:
2703:
2700:
2698:
2695:
2693:
2690:
2688:
2685:
2683:
2680:
2678:
2675:
2673:
2670:
2668:
2667:Lactucopicrin
2665:
2663:
2660:
2658:
2655:
2653:
2650:
2648:
2645:
2643:
2640:
2638:
2635:
2633:
2630:
2628:
2625:
2623:
2620:
2618:
2615:
2613:
2610:
2608:
2605:
2603:
2600:
2598:
2595:
2593:
2590:
2587:
2586:
2583:
2580:
2577:
2576:
2571:
2568:
2565:
2561:
2557:
2553:
2549:
2546:
2544:
2540:
2537:
2535:
2532:
2530:
2527:
2525:
2522:
2520:
2517:
2515:
2512:
2510:
2507:
2505:
2502:
2500:
2499:Trichloronate
2497:
2495:
2492:
2490:
2487:
2485:
2482:
2480:
2477:
2475:
2472:
2470:
2467:
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2462:
2460:
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2455:
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2407:
2405:
2402:
2400:
2397:
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2377:
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2367:
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2355:
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2332:
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2327:
2325:
2322:
2320:
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2312:
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2307:
2305:
2302:
2300:
2297:
2295:
2292:
2290:
2287:
2285:
2282:
2280:
2277:
2275:
2274:Monocrotophos
2272:
2270:
2267:
2265:
2262:
2260:
2257:
2255:
2252:
2250:
2247:
2245:
2242:
2240:
2239:Methamidophos
2237:
2235:
2232:
2230:
2227:
2225:
2222:
2220:
2217:
2215:
2212:
2210:
2207:
2205:
2202:
2200:
2197:
2195:
2192:
2190:
2187:
2185:
2182:
2180:
2177:
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2172:
2170:
2167:
2165:
2162:
2160:
2157:
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2150:
2147:
2145:
2142:
2140:
2137:
2135:
2132:
2130:
2127:
2125:
2122:
2120:
2117:
2115:
2114:Echothiophate
2112:
2110:
2107:
2105:
2102:
2100:
2097:
2095:
2092:
2090:
2087:
2085:
2082:
2080:
2077:
2075:
2072:
2070:
2067:
2065:
2062:
2060:
2057:
2055:
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2050:
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2037:
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2032:
2030:
2027:
2025:
2022:
2020:
2017:
2015:
2012:
2010:
2007:
2005:
2002:
2000:
1997:
1995:
1992:
1990:
1987:
1985:
1982:
1980:
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1972:
1970:
1967:
1965:
1962:
1960:
1957:
1955:
1952:
1950:
1947:
1945:
1942:
1940:
1937:
1935:
1932:
1930:
1927:
1925:
1922:
1920:
1916:
1915:Irreversible:
1913:
1912:
1909:
1906:
1904:
1901:
1899:
1896:
1894:
1891:
1889:
1886:
1884:
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1826:
1824:
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1811:
1809:
1806:
1804:
1801:
1799:
1796:
1794:
1790:
1787:
1785:
1782:
1780:
1779:Quilostigmine
1777:
1775:
1772:
1770:
1769:Physostigmine
1767:
1765:
1762:
1760:
1757:
1754:
1752:
1749:
1747:
1744:
1742:
1739:; Stigmines:
1738:
1735:
1733:
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1728:
1725:
1723:
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1715:
1713:
1710:
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1640:
1638:
1637:Chloropropham
1635:
1633:
1630:
1628:
1625:
1623:
1620:
1618:
1615:
1613:
1610:
1608:
1605:
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1598:
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1497:
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1491:
1486:
1480:
1477:
1473:
1467:
1463:
1459:
1456:
1452:
1449:
1448:Acetylcholine
1442:
1437:
1435:
1430:
1428:
1423:
1422:
1419:
1411:
1407:
1403:
1402:
1398:
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1384:
1379:
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1348:
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1324:
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1277:
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1247:
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1208:
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1200:
1196:
1192:
1188:
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1177:
1174:
1169:
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1148:
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1139:
1134:
1130:
1126:
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1116:
1112:
1108:
1104:
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1096:
1089:
1086:
1073:
1071:
1065:
1059:
1056:
1050:
1045:
1041:
1037:
1031:
1028:
1023:
1019:
1017:9783527607495
1013:
1009:
1008:
1000:
997:
984:
980:
974:
972:
970:
968:
966:
964:
962:
960:
958:
954:
949:
945:
941:
937:
933:
929:
925:
921:
917:
910:
907:
902:
900:9789241547659
896:
892:
888:
884:
880:
874:
871:
864:
862:
860:
852:
850:
848:
844:
839:
837:
833:
829:
825:
824:acetylcholine
821:
817:
813:
810:
806:
798:
793:
790:
789:
788:
782:
779:
776:
773:
770:
767:
764:
761:
758:
755:
752:
751:
750:
744:
742:
736:
734:
732:
728:
724:
719:
717:
713:
708:
706:
701:
699:
695:
691:
687:
683:
679:
671:
669:
667:
663:
658:
656:
655:acetylcholine
652:
648:
644:
640:
636:
632:
627:
625:
621:
617:
613:
609:
605:
595:
588:
579:
574:
570:
563:
554:
550:
543:
536:
532:
531:
529:
526:
521:
514:
512:
508:
481:
479:
475:
470:
462:
458:
454:
453:
451:
442:
438:
431:
427:
426:
424:
422:
418:
411:
407:
406:
404:
402:
398:
391:
387:
386:
384:
382:
378:
371:
367:
366:
364:
362:
358:
351:
347:
346:
344:
342:
338:
331:
327:
326:
324:
317:
313:
306:
302:
301:
299:
297:
293:
284:
280:
273:
268:
265:
262:
260:
256:
252:
250:
243:
239:
237:
233:
229:
225:
219:
209:
206:
196:
195:
193:
191:
187:
182:
174:
169:
166:
165:
163:
161:
157:
154:
150:
147:
145:
141:
138:
134:
131:
129:
123:
117:
108:
107:
105:
103:
97:
93:
89:
87:
83:
79:
75:
73:
69:
65:
61:
59:
55:
52:Clinical data
50:
46:
41:
37:
32:
22:
21:Physostigmine
3067:
3061:α-Latrotoxin
3049:
3019:
2984:
2953:
2911:
2885:
2870:
2814:Rivastigmine
2780:
2734:Reactivators
2707:Ungiminorine
2662:Kobophenol A
2627:Coronaridine
2617:Bulbocapnine
2612:Arisugacin A
2588:
2573:
2459:Tebupirimfos
2339:Phosphamidon
2244:Methidathion
2149:Fenitrothion
1974:Chlorpyrifos
1914:
1789:Terestigmine
1784:Rivastigmine
1773:
1746:Eptastigmine
1697:Phenmedipham
1667:Formparanate
1652:Ethiofencarb
1585:Carbamates:
1582:
1576:
1495:
1409:
1378:
1322:
1318:
1312:
1279:
1275:
1233:
1229:
1223:
1190:
1186:
1176:
1165:
1155:
1102:
1098:
1088:
1076:. Retrieved
1067:
1058:
1049:10665/325771
1039:
1030:
1006:
999:
987:. Retrieved
923:
919:
909:
882:
873:
856:
840:
802:
786:
748:
745:Side effects
740:
720:
709:
702:
680:or forms of
675:
672:Medical uses
659:
628:
603:
602:
591:
246:Elimination
190:Legal status
184:Legal status
2912:Inhibitors:
2889:Coluracetam
2871:Inhibitors:
2841:Transporter
2781:Inhibitors:
2753:Pralidoxime
2647:Cyclanoline
2597:α-Viniferin
2494:Trichlorfon
2259:Metrifonate
2174:Fosthiazate
2159:Fluorotabun
2034:Dicrotophos
1989:Crotylsarin
1833:Huperzine A
1828:Galantamine
1823:Edrophonium
1756:Neostigmine
1751:Ganstigmine
1717:Propamocarb
1662:Formetanate
1647:Ethienocarb
1627:Carbosulfan
1617:Carbetamide
1612:Carbendazim
1583:Reversible:
1496:Inhibitors:
891:10665/44053
828:neostigmine
647:cholinergic
518: g·mol
270:Identifiers
137:intravenous
86:MedlinePlus
58:Trade names
3149:Categories
3076:versutoxin
3072:robustoxin
2946:Inhibitors
2935:modulators
2886:Enhancers:
2847:modulators
2804:Ladostigil
2794:Conodurine
2789:Affinisine
2702:Ungeremine
2677:Phosacetim
2637:Corynoline
2632:Corydaline
2622:Conodurine
2607:Affinisine
2543:Demecarium
2541:; Others:
2454:Tabun (GA)
2444:Soman (GD)
2434:Sarin (GB)
2354:Profenofos
2214:Isoxathion
2199:Guanitoxin
2169:Formothion
2144:Fenamiphos
2074:Disulfoton
2069:Dioxathion
2059:Dimethoate
2029:Dichlorvos
1863:Ladostigil
1853:Ipidacrine
1798:Ambenonium
1793:Acotiamide
1791:; Others:
1764:Phenserine
1741:Distigmine
1732:Thiodicarb
1707:Pirimicarb
1672:Methiocarb
1657:Fenobucarb
1632:Chlorbufam
1622:Carbofuran
1597:Bendiocarb
1578:Inhibitors
1472:modulators
1458:modulators
1451:metabolism
989:8 December
865:References
820:hydrolysis
686:curariform
523:3D model (
511:Molar mass
430:ChEMBL1115
390:19QM69HH21
361:ChemSpider
296:CAS Number
279:IUPAC name
240:7.6 ± 2.4%
144:Drug class
3058:agonists:
3042:Enhancers
2915:Vesamicol
2799:Cymserine
2748:Obidoxime
2743:Methoxime
2657:Harmaline
2652:Cymserine
2642:Crimidine
2589:Unsorted:
2484:Triazofos
2424:Ro 3-0433
2419:Ro 3-0422
2414:Ro 3-0419
2409:Ro 3-0417
2404:Ro 3-0412
2399:Ro 3-0411
2394:Ro 3-0397
2389:Ro 3-0352
2384:Ro 3-0351
2379:Ro 3-0347
2374:Ro 3-0346
2369:Ro 3-0340
2359:Prothoate
2329:Phosfolan
2324:Phosalone
2309:Parathion
2294:Omethoate
2264:Mevinphos
2229:Malathion
2219:Leptophos
2124:Endothion
2004:Demephion
1994:Cyanophos
1984:Coumaphos
1954:Cadusafos
1949:Bensulide
1944:BAY-29952
1908:Zanapezil
1868:Minaprine
1848:Huprine Y
1843:Huprine X
1838:Huprine W
1808:Donepezil
1737:Thiofanox
1712:Promecarb
1702:Pinmicarb
1682:Metolcarb
1642:Dimetilan
1602:Bufencarb
1592:Aminocarb
1544:CM-54,903
1455:transport
1215:244530010
948:244530010
832:carbamate
723:off-label
639:pregnancy
259:Excretion
248:half-life
126:Routes of
100:Pregnancy
78:Monograph
72:Drugs.com
3139:Medicine
3098:See also
3082:Crotoxin
2784:Affinine
2717:BW284C51
2672:Lycorine
2602:Affinine
2592:α-Pinene
2570:Onchidal
2489:Tribufos
2469:Terbufos
2439:Schradan
2304:Paraoxon
2224:Malaoxon
2154:Fenthion
2139:Ethoprop
2024:Diazinon
2019:Dialifor
1924:Acephate
1858:Itopride
1803:Caffeine
1727:Propoxur
1677:Methomyl
1607:Carbaryl
1587:Aldicarb
1386:Archived
1368:Archived
1347:20405336
1339:21410722
1304:22855759
1296:17284509
1258:22855759
1250:17284509
1207:34816481
1147:18332428
1129:25461411
1038:(2019).
1022:Archived
983:Archived
940:34816481
809:inhibits
762:Vomiting
756:Diarrhea
753:Sweating
694:Gulf War
624:by mouth
612:atropine
594:(verify)
341:DrugBank
305:155-97-5
160:ATC code
133:By mouth
102:category
3068:Others:
3020:Others:
2956:SNAP-25
2929:Release
2819:Tacrine
2727:3152 CT
2692:Taspine
2464:Temefos
2364:R-16661
2334:Phosmet
2319:Phorate
2269:Mipafox
2234:Mazidox
2164:Fonofos
2109:EA-4352
2104:EA-3148
2099:EA-2613
2094:EA-2192
2089:EA-2098
2084:EA-2054
2079:EA-2012
2054:Dimefox
2009:Demeton
1903:Tacrine
1898:TL-1238
1818:EA-4056
1813:EA-3990
1722:Propham
1687:Miotine
1167:Reuters
1138:2393741
1107:Bibcode
1078:6 March
814:in the
771:Tearing
645:in the
618:of the
516:181.215
478:Formula
350:DB00545
316:PubChem
176:)
170: (
168:N07AA02
115: C
92:a682229
3125:Portal
2429:Ronnel
2344:Phoxim
2134:Ethion
1929:Armine
1893:TL-599
1888:T-1194
1883:T-1152
1878:T-1123
1692:Oxamyl
1466:Enzyme
1345:
1337:
1302:
1294:
1256:
1248:
1213:
1205:
1145:
1135:
1127:
1014:
946:
938:
897:
843:sodium
759:Nausea
549:SMILES
421:ChEMBL
410:C07410
264:kidney
218:℞-only
216:
203:
2900:VAChT
2722:TMTFA
2284:Naled
2189:GT-45
2179:GD-42
1529:AF64A
1343:S2CID
1300:S2CID
1254:S2CID
1211:S2CID
1125:JSTOR
1072:(FDA)
1068:U.S.
944:S2CID
853:Names
807:. It
690:Soman
569:InChI
525:JSmol
3052:LPHN
2987:VAMP
2769:BChE
2279:MSPI
1565:AChE
1539:BETA
1534:B115
1484:ChAT
1453:and
1335:PMID
1292:PMID
1246:PMID
1203:PMID
1143:PMID
1080:2023
1012:ISBN
991:2016
936:PMID
895:ISBN
725:for
401:KEGG
381:UNII
370:4817
330:4991
230:data
68:AHFS
2859:CHT
2129:EPN
1327:doi
1284:doi
1238:doi
1195:doi
1133:PMC
1115:doi
1103:105
1044:hdl
928:doi
887:hdl
822:of
446:EPA
320:CID
205:POM
173:WHO
3151::
3074:,
3029:,
3010:,
3006:,
3002:,
2975:,
2971:,
2736::
2562:,
2558:,
2554:,
2539:VX
2534:VR
2529:VS
2524:VP
2519:VM
2514:VG
2509:VE
2194:GV
2184:GH
1408:.
1355:^
1341:.
1333:.
1323:34
1321:.
1298:.
1290:.
1280:41
1278:.
1266:^
1252:.
1244:.
1234:41
1232:.
1209:.
1201:.
1191:41
1189:.
1185:.
1164:.
1141:.
1131:.
1123:.
1113:.
1101:.
1097:.
1066:.
1020:.
956:^
942:.
934:.
924:41
922:.
918:.
893:.
733:.
718:.
700:.
668:.
657:.
492:13
212:US
199:UK
151:;
135:,
111:AU
3127::
3078:)
3033:)
3025:(
3014:)
3012:G
3008:F
3004:D
3000:B
2998:(
2979:)
2977:E
2973:C
2969:A
2967:(
2937:)
2933:(
2849:)
2845:(
2578:)
2572:(
2566:)
2564:4
2560:3
2556:2
2552:1
2550:(
1580::
1474:)
1470:(
1440:e
1433:t
1426:v
1349:.
1329::
1306:.
1286::
1260:.
1240::
1217:.
1197::
1170:.
1149:.
1117::
1109::
1082:.
1046::
993:.
950:.
930::
903:.
889::
527:)
504:2
501:O
498:2
495:N
489:H
486:9
483:C
448:)
444:(
214::
201::
113::
70:/
23:.
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