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2024:
Butler, Christopher C; Hobbs, F D Richard; Gbinigie, Oghenekome A; Rahman, Najib M; Hayward, Gail; Richards, Duncan B; Dorward, Jienchi; Lowe, David M; Standing, Joseph F; Breuer, Judith; Khoo, Saye; Petrou, Stavros; Hood, Kerenza; Nguyen-Van-Tam, Jonathan S; Patel, Mahendra G (22 December 2022).
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1682:. The study aims to find out if antivirals can prevent the need for hospitalisation and help faster recovery for people aged over 50 and those at higher risk due to underlying health conditions. PANORAMIC is sponsored by the
2847:
1747:
In
December 2022, results from the trial showed that for higher risk, vaccinated adults molnupiravir does not reduce the chances of hospitalisation and death. However it leads to faster recovery and reduced viral load.
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1223:
1259:
2027:"Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial"
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People can enroll in the study if they had symptoms of COVID (confirmed by a test) less than 5 days prior to enrolling. They have to be either aged 50 or over, or have a preexisting health condition.
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care and the other one will receive standard NHS care plus antiviral treatment. Participants can take part from home online or via phone and the antivirals are delivered to them.
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1690:(NIHR). The trial was launched in December 2021, and as of June 2022, over 25,000 people are enrolled as participants.
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Health
Protection (Coronavirus, Restrictions) (Entry to Venues and Events) (England) Regulations 2021
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2673:
2480:
1703:
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973:
919:
50:
Scientifically accurate atomic model of the external structure of SARS-CoV-2. Each "ball" is an atom.
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Coronavirus, Restrictions (All Tiers and Self-Isolation) (England) (Amendment) Regulations 2021
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Platform
Adaptive Trial of Novel Antivirals for Early Treatment of COVID-19 in the Community
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Health
Protection (Coronavirus, Restrictions) (Self-Isolation) (England) Regulations 2020
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Health
Protection (Coronavirus, Wearing of Face Coverings) (England) Regulations 2021
2893:
Coronavirus, Restrictions (Local
Authority Enforcement...) (England) Regulations 2020
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19:
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2908:
Coronavirus, International Travel and
Operator Liability (England) Regulations 2021
2662:
1727:
1947:"Over ten thousand participants enrol in world's largest COVID-19 antiviral study"
2075:"Pill for Covid does not reduce risk of hospitalisation or death, UK study finds"
3610:
3364:
3272:
3247:
2898:
Health
Protection (Coronavirus, Restrictions) (England) (No. 3) Regulations 2020
2863:
Health
Protection (Coronavirus, Restrictions) (England) (No. 4) Regulations 2020
3344:
3267:
2000:"Second ground-breaking antiviral to be deployed to country's most vulnerable"
1368:
963:
730:
65:
2843:
Health
Protection (Coronavirus, Business Closure) (England) Regulations 2020
2505:
1102:
953:
2060:
1815:
2475:
1679:
59:
2848:
Health Protection (Coronavirus, Restrictions) (England) Regulations 2020
958:
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2730:
Parliamentary Under-Secretary of State for COVID-19 Vaccine Deployment
45:
3566:
1787:
2105:
1867:"Covid cost-cutting will put blinkers on our best Covid research"
1842:"Public urged to sign up to world-first COVID-19 antiviral study"
2868:
Coronavirus, Restrictions (All Tiers) (England) Regulations 2020
2121:
2883:
Face Coverings in a Relevant Place (England) Regulations 2020
2878:
Face Coverings on Public Transport (England) Regulations 2020
2931:
Coronavirus, Restrictions (No. 2) (England) Regulations 2020
2888:
Coronavirus, Restrictions (Steps) (England) Regulations 2021
2873:
Coronavirus, International Travel (England) Regulations 2020
18:
3202:
New and Emerging Respiratory Virus Threats Advisory Group
1816:"Thousands needed to try a new Covid antiviral treatment"
1674:
in the United Kingdom to test the effectiveness of new
3659:
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16:
Clinical trial of antivirals for COVID-19 infection
3731:United Kingdom responses to the COVID-19 pandemic
2838:Health Protection (Coronavirus) Regulations 2020
3197:Joint Committee on Vaccination and Immunisation
2793:Stamp Duty Land Tax (Temporary Relief) Act 2020
1919:"PANORAMIC view of World's largest COVID study"
1893:"NIHR funds community COVID-19 antiviral trial"
1688:National Institute for Health and Care Research
2853:COVID-19 local lockdown regulations in England
2133:
1643:
8:
3520:Hold Still: A Portrait of Our Nation in 2020
2798:Corporate Insolvency and Governance Act 2020
2720:Vaccines Manufacturing and Innovation Centre
2376:Saint Helena, Ascension and Tristan da Cunha
1941:
1939:
1702:that will compare two groups who are having
2763:Public Health (Control of Disease) Act 1984
1726:The antivirals tested in the study will be
3726:Medical responses to the COVID-19 pandemic
3303:
2964:
2858:First COVID-19 tier regulations in England
2755:
2748:
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2140:
2126:
2118:
2110:
1650:
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25:
3207:Scientific Advisory Group for Emergencies
2050:
3721:COVID-19 pandemic in the United Kingdom
3666:
3182:Imperial College COVID-19 Response Team
2713:European Commission–AstraZeneca dispute
2149:COVID-19 pandemic in the United Kingdom
1779:
1376:Neurological and psychological symptoms
37:
3601:COVID-19 Bereaved Families for Justice
1975:"Participant Information — PANORAMIC"
7:
3022:Cabinet Secretary for Covid Recovery
1969:
1967:
1810:
1808:
3716:Clinical trials related to COVID-19
2708:Oxford–AstraZeneca COVID-19 vaccine
1917:Pinching, John (22 February 2022).
3036:Coughs and sneezes spread diseases
2511:Privileges Committee investigation
14:
3693:
3681:
3669:
3643:
2977:Coronavirus Job Retention Scheme
1619:
2562:COVID-19 Genomics UK Consortium
3017:Can you look them in the eyes?
2803:Business and Planning Act 2020
2341:British Indian Ocean Territory
1:
2043:10.1016/S0140-6736(22)02597-1
3631:National Covid Memorial Wall
2157:British Overseas Territories
1706:: one will receive standard
1400:Alzheimer's disease patients
925:Misinformation and hesitancy
3002:National Tutoring Programme
2778:Contingencies Fund Act 2021
2773:Contingencies Fund Act 2020
3747:
2458:National Day of Reflection
3639:
3596:Coronavirus Tech Handbook
3041:Catch It, Bin It, Kill It
2758:
2557:Cancer Monitoring Project
2523:Scottish COVID-19 Inquiry
2163:
1758:COVID-19 drug development
709:World Health Organization
3192:Joint Biosecurity Centre
2690:UK Rapid Test Consortium
2528:Virtual House of Commons
2486:Dominic Cummings scandal
2418:Exam grading controversy
2381:Turks and Caicos Islands
879:Public health mitigation
563:By country and territory
3027:Pre-pandemic exercises
2997:Global Travel Taskforce
2783:Coronavirus mini-budget
2501:Northern Research Group
1678:at the early stages of
1381:Post-exertional malaise
721:Undercounting of deaths
3606:Death of Belly Mujinga
2982:Contract controversies
2346:British Virgin Islands
1979:www.panoramictrial.org
1792:www.panoramictrial.org
1732:nirmatrelvir/ritonavir
1539:Science and technology
1415:Death rates by country
629:International response
51:
23:
3621:London Blossom Garden
2813:Culture Recovery Fund
2700:Vaccination programme
2406:Cost-of-living crisis
2326:Akrotiri and Dhekelia
1564:Xenophobia and racism
1430:Emergency evacuations
49:
22:
3381:Catherine Calderwood
3064:Overseas territories
2913:Coronavirus Act 2020
2674:Test, Trace, Protect
2481:COVID Recovery Group
2318:Overseas Territories
1684:University of Oxford
1299:Association football
920:Operation Warp Speed
3650:COVID-19 portal
3474:"Can You Hear Me" (
2992:Eat Out to Help Out
2788:Winter Economy Plan
2592:Temporary hospitals
2567:COVID Symptom Study
2552:Antiviral Taskforce
2438:Clap for Our Carers
1680:COVID-19 infections
1497:Other health issues
1024:Variants of concern
3506:Grayson's Art Club
3092:July–December 2020
2680:Operation Moonshot
2668:NHS Test and Trace
2290:Crown Dependencies
2153:Crown Dependencies
2081:. 22 December 2022
2037:(10373): 281–293.
1873:. 21 February 2022
1686:and funded by the
989:Oxford–AstraZeneca
827:federal government
738:National responses
52:
24:
3657:
3656:
3591:Captain Tom Moore
3527:Isolation Stories
3499:Failures of State
3460:
3459:
3350:Charlotte McArdle
3108:Northern Ireland
3087:January–June 2020
3072:
3071:
2954:
2953:
2826:
2825:
2808:Nightingale Court
2738:
2737:
2655:Testing programme
2536:
2535:
2491:Greensill scandal
2453:The 2.6 Challenge
2389:
2388:
1822:. 25 January 2022
1704:symptoms of COVID
1660:
1659:
1425:Domestic violence
1334:Gridiron football
1169:Financial markets
942:Vaccine passports
689:Social distancing
650:International aid
39:COVID-19 pandemic
3738:
3698:
3697:
3686:
3685:
3674:
3673:
3672:
3665:
3648:
3647:
3546:Pandemic Diaries
3360:Michelle O'Neill
3333:Northern Ireland
3319:Amanda Pritchard
3304:
3288:Jonathan Van-Tam
3283:Patrick Vallance
3187:Independent SAGE
3007:Pick for Britain
2965:
2756:
2749:
2663:NHS COVID-19 app
2588:
2496:Impact on Brexit
2426:
2371:Pitcairn Islands
2356:Falkland Islands
2270:Northern Ireland
2246:
2142:
2135:
2128:
2119:
2114:
2109:
2108:
2106:Official website
2091:
2090:
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2015:
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2010:
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1768:Solidarity trial
1652:
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1132:Arts and culture
948:Current vaccines
874:Drug repurposing
869:Drug development
846:Medical response
26:
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3635:
3626:Lineage B.1.1.7
3579:
3492:Emergency State
3466:
3456:
3447:Vaughan Gething
3425:
3411:Nicola Sturgeon
3386:Joe FitzPatrick
3369:
3355:Michael McBride
3328:
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3174:
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3031:Exercise Cygnus
2950:
2923:
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2685:Test to Release
2649:
2586:
2582:PANORAMIC trial
2572:COVID passports
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1698:PANORAMIC is a
1696:
1676:antiviral drugs
1668:PANORAMIC Trial
1656:
1626:COVID-19 portal
1618:
1613:
1612:
1527:Catholic Church
1502:Popular culture
1364:
1354:
1353:
1194:Performing arts
1127:
1121:Economic impact
1113:
1112:
1108:Lineage B.1.617
1019:
1009:
1008:
994:Pfizer–BioNTech
852:Disease testing
847:
839:
838:
682:Fake treatments
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3616:Notable deaths
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3540:Lockdown Files
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3442:Mark Drakeford
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3437:Frank Atherton
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3059:United Kingdom
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2577:RECOVERY Trial
2574:
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2098:External links
2096:
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2066:
2016:
1991:
1963:
1951:www.nihr.ac.uk
1935:
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1897:www.nihr.ac.uk
1884:
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1763:RECOVERY Trial
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672:Misinformation
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2448:Thank You NHS
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2227:
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2219:July–December
2217:
2215:
2212:
2211:
2209:
2205:
2204:July–December
2202:
2200:
2197:
2196:
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2189:July–December
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1477:Mental health
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1325:
1322:
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1314:Combat sports
1312:
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1219:sportscasting
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1179:Food security
1177:
1175:
1174:Food industry
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726:COVID-19 apps
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635:Endemic phase
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3574:This England
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3483:
3475:
3421:Humza Yousaf
3416:John Swinney
3406:Devi Sridhar
3401:Gregor Smith
3396:Jason Leitch
3293:Chris Whitty
3263:Phil Prosser
3258:Wei Shen Lim
3238:Dido Harding
3233:Matt Hancock
3223:Kevin Fenton
2581:
2214:January–June
2199:January–June
2184:January–June
2083:. Retrieved
2079:the Guardian
2078:
2069:
2034:
2030:
2019:
2007:. Retrieved
2003:
1994:
1982:. Retrieved
1978:
1954:. Retrieved
1950:
1926:. Retrieved
1922:
1912:
1900:. Retrieved
1896:
1887:
1875:. Retrieved
1871:the Guardian
1870:
1861:
1849:. Retrieved
1845:
1836:
1824:. Retrieved
1819:
1795:. Retrieved
1791:
1782:
1746:
1743:Molnupiravir
1734:(Paxlovid).
1728:molnupiravir
1725:
1717:
1714:Participants
1697:
1667:
1663:
1661:
1544:Social media
1405:Black people
1349:Rugby league
1329:Gaelic games
937:Vaccine card
857:Breathalyzer
612:Cruise ships
3611:EveryDoctor
3560:Preventable
3534:Locked Down
3486:(series 35)
3365:Robin Swann
3273:Rishi Sunak
3248:Sajid Javid
2818:2021 budget
2768:2020 budget
2744:Legislation
2303:Isle of Man
2085:29 December
1923:PharmaTimes
1788:"PANORAMIC"
1593:New Zealand
1447:Environment
1270:New Zealand
1238:Video games
862:Development
795:Philippines
785:New Zealand
780:Netherlands
640:Evacuations
617:Naval ships
3710:Categories
3467:depictions
3345:Paul Givan
3268:June Raine
3216:Key people
3024:(Scotland)
2969:Government
2623:Washington
2618:Manchester
2603:Birmingham
2545:healthcare
2366:Montserrat
2173:Statistics
2031:The Lancet
1774:References
1722:Treatments
1559:Telehealth
1420:Disability
1369:Long COVID
1344:Motorsport
1339:Ice hockey
1309:Basketball
1244:By country
1209:Television
1184:Journalism
964:Convidecia
910:Deployment
815:government
731:Zero-COVID
665:by country
645:Face masks
575:Antarctica
66:SARS-CoV-2
3553:Partygate
3128:Scotland
3077:Timelines
2960:Responses
2725:Taskforce
2670:(England)
2640:Gibraltar
2608:Harrogate
2506:Partygate
2413:Education
2361:Gibraltar
2242:Locations
2177:Timeline
1578:Diplomacy
1512:Pregnancy
1482:Migration
1452:Hospitals
1435:Education
1324:Disc golf
1125:recession
1103:Cluster 5
1004:Sputnik V
954:CoronaVac
660:Lockdowns
556:Locations
524:responses
512:responses
507:September
500:responses
488:responses
476:responses
464:responses
452:responses
440:responses
428:responses
416:responses
397:responses
385:responses
373:responses
361:responses
356:September
349:responses
337:responses
325:responses
313:responses
301:responses
289:responses
277:responses
265:responses
246:responses
234:responses
222:responses
210:responses
205:September
198:responses
186:responses
174:responses
162:responses
150:responses
138:responses
126:responses
114:responses
62:(disease)
3700:COVID-19
3676:Medicine
3584:See also
3484:Casualty
3374:Scotland
3173:Advisory
3083:England
3052:Military
2987:Lockdown
2924:or spent
2599:England
2476:Beergate
2468:Politics
2443:Protests
2331:Anguilla
2298:Guernsey
2275:Scotland
2061:36566761
2009:16 March
1984:16 March
1956:16 March
1928:16 March
1902:16 March
1877:16 March
1851:16 March
1826:16 March
1820:BBC News
1797:16 March
1752:See also
1694:Overview
1588:Malaysia
1571:Politics
1554:Suicides
1522:Religion
1507:Protests
1487:Military
1457:Language
1304:Baseball
1292:By sport
1265:Malaysia
1224:programs
1204:Shipping
1142:Cannabis
1137:Aviation
1017:Variants
898:Research
886:Vaccines
694:Software
536:December
531:November
423:February
392:December
380:November
272:February
241:December
229:November
121:February
90:Timeline
60:COVID-19
31:a series
29:Part of
3688:Viruses
3662:Portals
3476:Doctors
3307:England
2922:Expired
2831:Revoked
2752:Current
2676:(Wales)
2635:Cardiff
2630:Glasgow
2541:Science
2430:Society
2401:Economy
2336:Bermuda
2258:England
2168:History
2052:9779781
1738:Results
1670:) is a
1583:Ireland
1549:Strikes
1517:Prisons
1395:Animals
1388:Society
1362:Impacts
1319:Cricket
1260:Ireland
1233:Tourism
1164:Fashion
1063:Epsilon
1051:Omicron
984:Novavax
979:Moderna
974:Medigen
969:Janssen
959:Covaxin
893:History
834:Vietnam
790:Nigeria
775:Ireland
760:Germany
595:Oceania
519:October
411:January
368:October
260:January
217:October
109:January
68:(virus)
3567:Staged
3175:bodies
3148:Wales
2645:Jersey
2613:London
2394:Impact
2308:Jersey
2263:London
2059:
2049:
2004:GOV.UK
1846:GOV.UK
1598:Russia
1440:Female
1275:Russia
1250:Canada
1199:Retail
1159:Disney
1147:Cinema
1093:Lambda
805:Sweden
800:Russia
745:Africa
699:Travel
655:Origin
585:Europe
570:Africa
495:August
344:August
193:August
79:Deaths
33:on the
3465:Media
3430:Wales
2280:Wales
2210:2022
2195:2021
2180:2020
1410:Crime
1255:India
1189:Music
1152:films
1088:Kappa
1078:Theta
1046:Delta
1041:Gamma
1031:Alpha
770:India
765:Ghana
750:China
447:April
435:March
296:April
284:March
145:April
133:March
74:Cases
3513:Help
3162:2022
3157:2021
3152:2020
3142:2022
3137:2021
3132:2020
3122:2022
3117:2021
3112:2020
3102:2022
3097:2021
2231:2024
2226:2023
2155:and
2087:2022
2057:PMID
2011:2022
1986:2022
1958:2022
1930:2022
1904:2022
1879:2022
1853:2022
1828:2022
1799:2022
1730:and
1662:The
1532:Hajj
1123:and
1083:Iota
1068:Zeta
1036:Beta
903:VITT
580:Asia
543:2023
483:July
471:June
405:2022
332:July
320:June
254:2021
181:July
169:June
103:2020
97:2019
2543:and
2047:PMC
2039:doi
2035:401
1708:NHS
1073:Eta
459:May
308:May
157:May
3712::
2151:,
2077:.
2055:.
2045:.
2033:.
2029:.
2002:.
1977:.
1966:^
1949:.
1938:^
1921:.
1895:.
1869:.
1844:.
1818:.
1807:^
1790:.
1608:US
1603:UK
1285:US
1280:UK
1214:US
1098:Mu
930:US
822:US
810:UK
3664::
3478:)
2141:e
2134:t
2127:v
2089:.
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2041::
2013:.
1988:.
1960:.
1932:.
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1830:.
1801:.
1666:(
1651:e
1644:t
1637:v
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