330:
307:
204:
229:
2297:
595:
588:
581:
336:
235:
29:
2325:
2040:
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T,
2119:
Chevanne M, Calia C, Zampieri M, Cecchinelli B, Caldini R, Monti D, Bucci L, Franceschi C, Caiafa P (June 2007). "Oxidative DNA damage repair and parp 1 and parp 2 expression in
Epstein-Barr virus-immortalized B lymphocyte cells from young subjects, old subjects, and centenarians".
55:
1168:, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the
1183:, PARP2 plays more significant roles than PARP1 in protective responses to DNA damage and bacterial pathogenesis. The plant PARP2 carries N-terminal SAP DNA binding motifs rather than the Zn-finger DNA binding motifs of plant and animal PARP1 proteins.
2149:
Liang YC, Hsu CY, Yao YL, Yang WM (February 2013). "PARP-2 regulates cell cycle-related genes through histone deacetylation and methylation independently of poly(ADP-ribosyl)ation".
2296:
343:
242:
1164:
domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl)
863:
844:
165:
1324:
Johansson M (May 1999). "A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADP-ribose) polymerase homologues".
1906:
Still IH, Vince P, Cowell JK (December 1999). "Identification of a novel gene (ADPRTL1) encoding a potential Poly(ADP-ribosyl)transferase protein".
1838:"pADPRT-2: a novel mammalian polymerizing(ADP-ribosyl)transferase gene related to truncated pADPRT homologues in plants and Caenorhabditis elegans"
2394:
2043:"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes"
2370:
2389:
2276:
1306:
1288:
1972:"Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc"
329:
1555:
Suskiewicz MJ, Zobel F, Ogden TE, Fontana P, Ariza A, Yang JC, Zhu K, Bracken L, Hawthorne WJ, Ahel D, Neuhaus D, Ahel I (March 2020).
2230:
1071:
1078:
306:
1871:
Amé JC, Rolli V, Schreiber V, Niedergang C, Apiou F, Decker P, Muller S, Höger T, Ménissier-de Murcia J, de Murcia G (June 1999).
1397:
1937:"Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1"
1467:"Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1"
1275:
1254:
228:
203:
1271:
2242:
1787:"Oscillations of redox states in synchronously dividing cultures of Acanthamoeba castellanii and Schizosaccharomyces pombe"
52:
1250:
145:
1208:
342:
241:
1615:
Gaullier G, Roberts G, Muthurajan UM, Bowerman S, Rudolph J, Mahadevan J, Jha A, Rae PS, Luger K (3 November 2020).
1176:
targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.
2363:
1145:
335:
234:
2269:
1935:
Schreiber V, Amé JC, Dollé P, Schultz I, Rinaldi B, Fraulob V, Ménissier-de Murcia J, de Murcia G (June 2002).
1465:
Schreiber V, Amé JC, Dollé P, Schultz I, Rinaldi B, Fraulob V, Ménissier-de Murcia J, de Murcia G (June 2002).
908:
153:
1359:
Yélamos J, Schreiber V, Dantzer F (April 2008). "Toward specific functions of poly(ADP-ribose) polymerase-2".
889:
2356:
217:
1617:"Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1"
2262:
2180:"PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses"
1798:
1736:
1628:
1568:
1416:"PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses"
2248:
2236:
1029:
978:
132:
2007:"Poly(ADP-ribose) reactivates stalled DNA topoisomerase I and Induces DNA strand break resealing"
177:
1054:
1033:
1003:
982:
2211:
2166:
2137:
2107:
2072:
2028:
1993:
1958:
1923:
1894:
1859:
1824:
1762:
1705:
1656:
1594:
1537:
1508:"HPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation Activity"
1488:
1447:
1376:
1341:
594:
587:
580:
125:
45:
2201:
2191:
2158:
2129:
2097:
2062:
2054:
2018:
1983:
1948:
1915:
1884:
1849:
1814:
1806:
1752:
1744:
1695:
1687:
1646:
1636:
1584:
1576:
1527:
1519:
1478:
1437:
1427:
1368:
1333:
422:
353:
297:
252:
173:
1219:
397:
1802:
1740:
1632:
1572:
2340:
2206:
2179:
2067:
2042:
1819:
1786:
1757:
1724:
1700:
1675:
1651:
1616:
1589:
1556:
1532:
1507:
1442:
1415:
1192:
28:
2305:: CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF MURINE POLY (ADP-RIBOSE) POLYMERASE-2
1854:
1837:
1810:
778:
773:
768:
763:
758:
753:
748:
743:
738:
733:
728:
723:
718:
702:
697:
692:
687:
671:
666:
661:
656:
651:
646:
641:
636:
2383:
2336:
623:
157:
1169:
415:
194:
136:, ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2, poly(ADP-ribose) polymerase 2
2196:
1641:
1523:
1432:
1372:
181:
1311:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1293:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1165:
2162:
498:
2086:"PARP-2 interacts with TTF-1 and regulates expression of surfactant protein-B"
1970:
Saxena A, Wong LH, Kalitsis P, Earle E, Shaffer LG, Choo KH (September 2002).
1748:
1580:
754:
positive regulation of cell growth involved in cardiac muscle cell development
314:
211:
161:
2084:
Maeda Y, Hunter TC, Loudy DE, Davé V, Schreiber V, Whitsett JA (April 2006).
1988:
1971:
1889:
1872:
1557:"HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation"
1873:"PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase"
1196:
1173:
1161:
808:
558:
436:
381:
368:
280:
267:
169:
2215:
2170:
2141:
2111:
2102:
2085:
2076:
2032:
2023:
2006:
1997:
1962:
1953:
1936:
1927:
1919:
1898:
1863:
1766:
1709:
1660:
1598:
1541:
1492:
1483:
1466:
1451:
1380:
1345:
1337:
2133:
1828:
1118:
1113:
1691:
1102:
953:
934:
2058:
1157:
920:
875:
1195:
anti-cancer drugs (primarily aimed at PARP1) also inhibit PARP2, e.g.
102:
98:
94:
90:
86:
82:
78:
74:
1134:
1086:
830:
2324:
1398:"Entrez Gene: PARP2 poly (ADP-ribose) polymerase family, member 2"
1212:
1725:"Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin"
793:
789:
2332:
2041:
Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006).
1141:
603:
149:
2258:
2254:
1723:
Bilokapic S, Suskiewicz MJ, Ahel I, Halic M (September 2020).
1226:
1836:
Berghammer H, Ebner M, Marksteiner R, Auer B (April 1999).
1676:"Structural basis for DNA break recognition by ARTD2/PARP2"
1506:
Gibbs-Seymour I, Fontana P, Rack JG, Ahel I (5 May 2016).
1785:
Bashford CL, Chance B, Lloyd D, Poole RK (January 1980).
405:
2344:
1156:
This gene encodes poly(ADP-ribosyl)transferase-like 2
1674:
Obaji E, Haikarainen T, Lehtiö L (14 December 2018).
570:
2151:
1047:
1022:
996:
971:
1267:
1265:
1263:
1246:
1244:
1242:
2178:Song J, Keppler BD, Wise RR, Bent AF (May 2015).
1414:Song J, Keppler BD, Wise RR, Bent AF (May 2015).
352:
251:
1610:
1608:
16:Protein-coding gene in the species Homo sapiens
1272:GRCm38: Ensembl release 89: ENSMUSG00000036023
2364:
2270:
8:
1251:GRCh38: Ensembl release 89: ENSG00000129484
2371:
2357:
2277:
2263:
2255:
1409:
1407:
804:
619:
393:
292:
189:
63:
2205:
2195:
2101:
2066:
2022:
1987:
1952:
1888:
1853:
1818:
1756:
1699:
1650:
1640:
1588:
1531:
1482:
1441:
1431:
1392:
1390:
779:cellular response to DNA damage stimulus
2292:
2005:Malanga M, Althaus FR (February 2004).
1238:
672:NAD DNA ADP-ribosyltransferase activity
18:
739:extrinsic apoptotic signaling pathway
357:
318:
313:
256:
215:
210:
7:
2321:
2319:
662:NAD+ ADP-ribosyltransferase activity
2090:The Journal of Biological Chemistry
2011:The Journal of Biological Chemistry
1941:The Journal of Biological Chemistry
1877:The Journal of Biological Chemistry
1471:The Journal of Biological Chemistry
759:negative regulation of neuron death
719:DNA ligation involved in DNA repair
1044:
1019:
993:
968:
944:
925:
899:
880:
854:
835:
575:
493:
431:
410:
14:
1225:PARP2 binds to and bridges blunt
1137:that in humans is encoded by the
2323:
2295:
749:peptidyl-serine ADP-ribosylation
593:
586:
579:
341:
334:
328:
305:
240:
233:
227:
202:
27:
667:protein ADP-ribosylase activity
2395:Human chromosome 14 gene stubs
604:More reference expression data
559:More reference expression data
451:right hemisphere of cerebellum
1:
1855:10.1016/S0014-5793(99)00448-2
1811:10.1016/S0006-3495(80)85114-9
769:protein poly-ADP-ribosylation
326:
225:
2390:Genes on human chromosome 14
2343:. You can help Knowledge by
2197:10.1371/journal.pgen.1005200
1642:10.1371/journal.pone.0240932
1524:10.1016/j.molcel.2016.03.008
1433:10.1371/journal.pgen.1005200
1373:10.1016/j.molmed.2008.02.003
1361:Trends in Molecular Medicine
657:glycosyltransferase activity
2235:human gene location in the
2411:
2318:
2247:human gene details in the
2163:10.1016/j.bbrc.2012.12.092
1218:PARP2 also interacts with
764:double-strand break repair
2290:
1749:10.1038/s41586-020-2725-7
1581:10.1038/s41586-020-2013-6
1307:"Mouse PubMed Reference:"
1289:"Human PubMed Reference:"
1117:
1112:
1108:
1101:
1085:
1066:
1051:
1026:
1015:
1000:
975:
964:
951:
947:
932:
928:
919:
906:
902:
887:
883:
874:
861:
857:
842:
838:
829:
814:
807:
803:
787:
724:lagging strand elongation
652:DNA ligase (ATP) activity
622:
618:
601:
578:
569:
556:
505:
496:
443:
434:
404:
396:
392:
375:
362:
325:
304:
295:
291:
274:
261:
224:
201:
192:
188:
143:
140:
130:
123:
118:
71:
66:
49:
44:
39:
35:
26:
21:
1976:Human Molecular Genetics
1890:10.1074/jbc.274.25.17860
1207:PARP2 has been shown to
1079:Chr 14: 51.05 – 51.06 Mb
1072:Chr 14: 20.34 – 20.36 Mb
729:protein ADP-ribosylation
2103:10.1074/jbc.M510435200
2024:10.1074/jbc.C300437200
1989:10.1093/hmg/11.19.2319
1954:10.1074/jbc.M202390200
1920:10.1006/geno.1999.6024
1680:Nucleic Acids Research
1484:10.1074/jbc.M202390200
1338:10.1006/geno.1999.5799
521:neural layer of retina
359:14 26.25 cM|14 C1
2134:10.1089/rej.2006.0514
2122:Rejuvenation Research
1179:In the plant species
447:cerebellar hemisphere
320:Chromosome 14 (mouse)
218:Chromosome 14 (human)
1187:PARP inhibitor drugs
1181:Arabidopsis thaliana
774:DNA ADP-ribosylation
744:base-excision repair
637:transferase activity
67:List of PDB id codes
40:Available structures
2249:UCSC Genome Browser
2237:UCSC Genome Browser
1803:1980BpJ....29....1B
1791:Biophysical Journal
1741:2020Natur.585..609B
1686:(22): 12154–12165.
1633:2020PLoSO..1540932G
1573:2020Natur.579..598S
1160:, which contains a
1148:family of enzymes.
1144:. It is one of the
471:ganglionic eminence
2331:This article on a
2059:10.1101/gr.4039406
1692:10.1093/nar/gky927
1131:Poly polymerase 2
909:ENSMUSG00000036023
712:Biological process
681:Cellular component
630:Molecular function
455:right frontal lobe
2352:
2351:
2313:
2312:
1735:(7826): 609–613.
1567:(7800): 598–602.
1128:
1127:
1124:
1123:
1097:
1096:
1062:
1061:
1041:
1040:
1011:
1010:
990:
989:
960:
959:
941:
940:
915:
914:
896:
895:
870:
869:
851:
850:
799:
798:
614:
613:
610:
609:
565:
564:
552:
551:
490:
489:
479:cerebellar vermis
475:prefrontal cortex
388:
387:
287:
286:
182:PARP2 - orthologs
114:
113:
110:
109:
50:Ortholog search:
2402:
2373:
2366:
2359:
2327:
2320:
2299:
2279:
2272:
2265:
2256:
2219:
2209:
2199:
2174:
2145:
2115:
2105:
2080:
2070:
2036:
2026:
2001:
1991:
1966:
1956:
1947:(25): 23028–36.
1931:
1902:
1892:
1867:
1857:
1832:
1822:
1771:
1770:
1760:
1720:
1714:
1713:
1703:
1671:
1665:
1664:
1654:
1644:
1627:(11): e0240932.
1612:
1603:
1602:
1592:
1552:
1546:
1545:
1535:
1503:
1497:
1496:
1486:
1477:(25): 23028–36.
1462:
1456:
1455:
1445:
1435:
1411:
1402:
1401:
1394:
1385:
1384:
1356:
1350:
1349:
1321:
1315:
1314:
1303:
1297:
1296:
1285:
1279:
1269:
1258:
1248:
1110:
1109:
1081:
1074:
1057:
1045:
1036:
1020:
1016:RefSeq (protein)
1006:
994:
985:
969:
945:
926:
900:
881:
855:
836:
805:
620:
606:
597:
590:
583:
576:
561:
541:primitive streak
533:ventricular zone
517:genital tubercle
513:Ileal epithelium
501:
499:Top expressed in
494:
467:ventricular zone
439:
437:Top expressed in
432:
411:
394:
384:
371:
360:
345:
338:
332:
321:
309:
293:
283:
270:
259:
244:
237:
231:
220:
206:
190:
184:
135:
128:
105:
64:
58:
37:
36:
31:
19:
2410:
2409:
2405:
2404:
2403:
2401:
2400:
2399:
2380:
2379:
2378:
2377:
2316:
2314:
2309:
2306:
2300:
2286:
2283:
2227:
2222:
2190:(5): e1005200.
2177:
2148:
2118:
2083:
2047:Genome Research
2039:
2004:
1982:(19): 2319–29.
1969:
1934:
1905:
1883:(25): 17860–8.
1870:
1848:(2–3): 259–63.
1835:
1784:
1780:
1778:Further reading
1775:
1774:
1722:
1721:
1717:
1673:
1672:
1668:
1614:
1613:
1606:
1554:
1553:
1549:
1505:
1504:
1500:
1464:
1463:
1459:
1426:(5): e1005200.
1413:
1412:
1405:
1396:
1395:
1388:
1358:
1357:
1353:
1323:
1322:
1318:
1305:
1304:
1300:
1287:
1286:
1282:
1270:
1261:
1249:
1240:
1235:
1205:
1189:
1154:
1119:View/Edit Mouse
1114:View/Edit Human
1077:
1070:
1067:Location (UCSC)
1053:
1032:
1028:
1002:
981:
977:
890:ENSG00000129484
783:
707:
676:
647:protein binding
602:
592:
591:
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584:
557:
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535:
531:
527:
523:
519:
515:
511:
497:
486:
481:
477:
473:
469:
465:
461:
459:Brodmann area 9
457:
453:
449:
435:
379:
366:
358:
348:
347:
346:
339:
319:
296:Gene location (
278:
265:
257:
247:
246:
245:
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216:
193:Gene location (
144:
131:
124:
73:
51:
17:
12:
11:
5:
2408:
2406:
2398:
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2392:
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2368:
2361:
2353:
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2311:
2310:
2308:
2307:
2301:
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2253:
2252:
2240:
2226:
2225:External links
2223:
2221:
2220:
2175:
2146:
2128:(2): 191–204.
2116:
2096:(14): 9600–6.
2081:
2037:
2002:
1967:
1932:
1903:
1868:
1833:
1781:
1779:
1776:
1773:
1772:
1715:
1666:
1604:
1547:
1518:(3): 432–442.
1512:Molecular Cell
1498:
1457:
1403:
1386:
1351:
1316:
1298:
1280:
1259:
1237:
1236:
1234:
1231:
1204:
1201:
1193:PARP inhibitor
1188:
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518:
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510:
509:tail of embryo
506:
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502:
491:
488:
487:
485:
484:
480:
476:
472:
468:
464:
460:
456:
452:
448:
444:
441:
440:
428:
427:
419:
408:
402:
401:
398:RNA expression
390:
389:
386:
385:
377:
373:
372:
364:
361:
356:
350:
349:
340:
333:
327:
323:
322:
317:
311:
310:
302:
301:
289:
288:
285:
284:
276:
272:
271:
263:
260:
255:
249:
248:
239:
232:
226:
222:
221:
214:
208:
207:
199:
198:
186:
185:
142:
138:
137:
129:
121:
120:
116:
115:
112:
111:
108:
107:
69:
68:
60:
59:
48:
42:
41:
33:
32:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
2407:
2396:
2393:
2391:
2388:
2387:
2385:
2374:
2369:
2367:
2362:
2360:
2355:
2354:
2348:
2346:
2342:
2338:
2337:chromosome 14
2334:
2329:
2326:
2322:
2317:
2304:
2298:
2293:
2289:
2280:
2275:
2273:
2268:
2266:
2261:
2260:
2257:
2250:
2246:
2245:
2241:
2238:
2234:
2233:
2229:
2228:
2224:
2217:
2213:
2208:
2203:
2198:
2193:
2189:
2185:
2184:PLOS Genetics
2181:
2176:
2172:
2168:
2164:
2160:
2156:
2152:
2147:
2143:
2139:
2135:
2131:
2127:
2123:
2117:
2113:
2109:
2104:
2099:
2095:
2091:
2087:
2082:
2078:
2074:
2069:
2064:
2060:
2056:
2052:
2048:
2044:
2038:
2034:
2030:
2025:
2020:
2017:(7): 5244–8.
2016:
2012:
2008:
2003:
1999:
1995:
1990:
1985:
1981:
1977:
1973:
1968:
1964:
1960:
1955:
1950:
1946:
1942:
1938:
1933:
1929:
1925:
1921:
1917:
1913:
1909:
1904:
1900:
1896:
1891:
1886:
1882:
1878:
1874:
1869:
1865:
1861:
1856:
1851:
1847:
1843:
1839:
1834:
1830:
1826:
1821:
1816:
1812:
1808:
1804:
1800:
1796:
1792:
1788:
1783:
1782:
1777:
1768:
1764:
1759:
1754:
1750:
1746:
1742:
1738:
1734:
1730:
1726:
1719:
1716:
1711:
1707:
1702:
1697:
1693:
1689:
1685:
1681:
1677:
1670:
1667:
1662:
1658:
1653:
1648:
1643:
1638:
1634:
1630:
1626:
1622:
1618:
1611:
1609:
1605:
1600:
1596:
1591:
1586:
1582:
1578:
1574:
1570:
1566:
1562:
1558:
1551:
1548:
1543:
1539:
1534:
1529:
1525:
1521:
1517:
1513:
1509:
1502:
1499:
1494:
1490:
1485:
1480:
1476:
1472:
1468:
1461:
1458:
1453:
1449:
1444:
1439:
1434:
1429:
1425:
1421:
1420:PLOS Genetics
1417:
1410:
1408:
1404:
1399:
1393:
1391:
1387:
1382:
1378:
1374:
1370:
1367:(4): 169–78.
1366:
1362:
1355:
1352:
1347:
1343:
1339:
1335:
1331:
1327:
1320:
1317:
1312:
1308:
1302:
1299:
1294:
1290:
1284:
1281:
1277:
1273:
1268:
1266:
1264:
1260:
1256:
1252:
1247:
1245:
1243:
1239:
1232:
1230:
1228:
1223:
1221:
1216:
1214:
1210:
1202:
1200:
1198:
1194:
1186:
1184:
1182:
1177:
1175:
1171:
1167:
1163:
1159:
1151:
1149:
1147:
1143:
1140:
1136:
1132:
1120:
1115:
1111:
1107:
1104:
1100:
1093:
1091:
1088:
1084:
1080:
1076:
1073:
1069:
1065:
1058:
1056:
1050:
1046:
1043:
1037:
1035:
1031:
1025:
1021:
1018:
1014:
1007:
1005:
999:
995:
992:
986:
984:
980:
974:
970:
967:
965:RefSeq (mRNA)
963:
956:
955:
950:
946:
943:
937:
936:
931:
927:
924:
922:
918:
911:
910:
905:
901:
898:
892:
891:
886:
882:
879:
877:
873:
866:
865:
860:
856:
853:
847:
846:
841:
837:
834:
832:
828:
825:
822:
820:
817:
813:
810:
806:
802:
795:
791:
786:
780:
777:
775:
772:
770:
767:
765:
762:
760:
757:
755:
752:
750:
747:
745:
742:
740:
737:
735:
732:
730:
727:
725:
722:
720:
717:
716:
714:
711:
710:
704:
701:
699:
696:
694:
691:
689:
686:
685:
683:
680:
679:
673:
670:
668:
665:
663:
660:
658:
655:
653:
650:
648:
645:
643:
640:
638:
635:
634:
632:
629:
628:
625:
624:Gene ontology
621:
617:
605:
600:
596:
589:
582:
577:
574:
572:
568:
560:
555:
544:
540:
536:
532:
528:
524:
520:
516:
512:
508:
507:
504:
500:
495:
492:
482:
478:
474:
470:
466:
462:
458:
454:
450:
446:
445:
442:
438:
433:
430:
429:
426:
424:
420:
418:
417:
413:
412:
409:
407:
403:
399:
395:
391:
383:
378:
374:
370:
365:
355:
351:
344:
337:
331:
324:
316:
312:
308:
303:
299:
294:
290:
282:
277:
273:
269:
264:
254:
250:
243:
236:
230:
223:
219:
213:
209:
205:
200:
196:
191:
187:
183:
179:
175:
171:
167:
163:
159:
155:
151:
147:
139:
134:
127:
122:
117:
106:
104:
100:
96:
92:
88:
84:
80:
76:
70:
65:
62:
61:
57:
54:
47:
43:
38:
34:
30:
25:
20:
2345:expanding it
2330:
2315:
2302:
2243:
2231:
2187:
2183:
2157:(1): 58–64.
2154:
2150:
2125:
2121:
2093:
2089:
2053:(1): 55–65.
2050:
2046:
2014:
2010:
1979:
1975:
1944:
1940:
1914:(3): 533–6.
1911:
1907:
1880:
1876:
1845:
1842:FEBS Letters
1841:
1794:
1790:
1732:
1728:
1718:
1683:
1679:
1669:
1624:
1620:
1564:
1560:
1550:
1515:
1511:
1501:
1474:
1470:
1460:
1423:
1419:
1364:
1360:
1354:
1332:(3): 442–5.
1329:
1325:
1319:
1310:
1301:
1292:
1283:
1224:
1217:
1206:
1203:Interactions
1190:
1180:
1178:
1155:
1138:
1130:
1129:
1052:
1030:NP_001036083
1027:
1001:
979:NM_001042618
976:
952:
933:
907:
888:
862:
843:
823:
818:
525:otic placode
421:
414:
141:External IDs
72:
2285:PDB gallery
1797:(1): 1–11.
1166:transferase
703:nucleoplasm
642:DNA binding
380:51,058,758
367:51,045,298
279:20,357,904
266:20,343,615
119:Identifiers
2384:Categories
1278:, May 2017
1257:, May 2017
1233:References
734:DNA repair
483:left ovary
425:(ortholog)
162:HomoloGene
2335:on human
1197:niraparib
1174:nucleolar
1162:catalytic
1055:NP_033762
1034:NP_005475
1004:NM_009632
983:NM_005484
809:Orthologs
693:nucleolus
688:cytoplasm
170:GeneCards
2216:25950582
2171:23291187
2142:17518695
2112:16461352
2077:16344560
2033:14699148
1998:12217960
1963:11948190
1928:10644454
1908:Genomics
1899:10364231
1864:10338144
1767:32939087
1710:30321391
1661:33141820
1621:PLOS ONE
1599:32028527
1542:27067600
1493:11948190
1452:25950582
1381:18353725
1346:10329013
1326:Genomics
1274:–
1253:–
1209:interact
1152:Function
1103:Wikidata
788:Sources:
529:epiblast
2207:4423837
2068:1356129
1829:7260241
1820:1328658
1799:Bibcode
1758:7529888
1737:Bibcode
1701:6294510
1652:7608914
1629:Bibcode
1590:7104379
1569:Bibcode
1533:4858568
1443:4423837
1276:Ensembl
1255:Ensembl
1172:and/or
1170:nuclear
1158:protein
921:UniProt
876:Ensembl
815:Species
794:QuickGO
698:nucleus
400:pattern
258:14q11.2
158:1341112
126:Aliases
2214:
2204:
2169:
2140:
2110:
2075:
2065:
2031:
1996:
1961:
1926:
1897:
1862:
1827:
1817:
1765:
1755:
1729:Nature
1708:
1698:
1659:
1649:
1597:
1587:
1561:Nature
1540:
1530:
1491:
1450:
1440:
1379:
1344:
1229:ends.
1135:enzyme
1133:is an
1089:search
1087:PubMed
954:O88554
935:Q9UGN5
831:Entrez
571:BioGPS
545:embryo
537:embryo
150:607725
2339:is a
2244:PARP2
2232:PARP2
1213:XRCC1
1211:with
1191:Some
1139:PARP2
864:11546
845:10038
824:Mouse
819:Human
790:Amigo
463:gonad
423:Mouse
416:Human
363:Start
298:Mouse
262:Start
195:Human
174:PARP2
133:PARP2
22:PARP2
2341:stub
2333:gene
2303:1gs0
2212:PMID
2167:PMID
2138:PMID
2108:PMID
2073:PMID
2029:PMID
1994:PMID
1959:PMID
1924:PMID
1895:PMID
1860:PMID
1825:PMID
1763:PMID
1706:PMID
1657:PMID
1595:PMID
1538:PMID
1489:PMID
1448:PMID
1377:PMID
1342:PMID
1220:HPF1
1146:PARP
1142:gene
406:Bgee
354:Band
315:Chr.
253:Band
212:Chr.
166:4004
146:OMIM
103:5D5K
99:5DSY
95:4ZZY
91:4ZZX
87:4TVJ
83:4PJV
79:3KJD
75:3KCZ
56:RCSB
53:PDBe
2202:PMC
2192:doi
2159:doi
2155:431
2130:doi
2098:doi
2094:281
2063:PMC
2055:doi
2019:doi
2015:279
1984:doi
1949:doi
1945:277
1916:doi
1885:doi
1881:274
1850:doi
1846:449
1815:PMC
1807:doi
1753:PMC
1745:doi
1733:585
1696:PMC
1688:doi
1647:PMC
1637:doi
1585:PMC
1577:doi
1565:579
1528:PMC
1520:doi
1479:doi
1475:277
1438:PMC
1428:doi
1369:doi
1334:doi
1227:DNA
376:End
275:End
178:OMA
154:MGI
46:PDB
2386::
2210:.
2200:.
2188:11
2186:.
2182:.
2165:.
2153:.
2136:.
2126:10
2124:.
2106:.
2092:.
2088:.
2071:.
2061:.
2051:16
2049:.
2045:.
2027:.
2013:.
2009:.
1992:.
1980:11
1978:.
1974:.
1957:.
1943:.
1939:.
1922:.
1912:62
1910:.
1893:.
1879:.
1875:.
1858:.
1844:.
1840:.
1823:.
1813:.
1805:.
1795:29
1793:.
1789:.
1761:.
1751:.
1743:.
1731:.
1727:.
1704:.
1694:.
1684:46
1682:.
1678:.
1655:.
1645:.
1635:.
1625:15
1623:.
1619:.
1607:^
1593:.
1583:.
1575:.
1563:.
1559:.
1536:.
1526:.
1516:62
1514:.
1510:.
1487:.
1473:.
1469:.
1446:.
1436:.
1424:11
1422:.
1418:.
1406:^
1389:^
1375:.
1365:14
1363:.
1340:.
1330:57
1328:.
1309:.
1291:.
1262:^
1241:^
1222:.
1215:.
1199:.
792:/
382:bp
369:bp
281:bp
268:bp
176:;
172::
168:;
164::
160:;
156::
152:;
148::
101:,
97:,
93:,
89:,
85:,
81:,
77:,
2372:e
2365:t
2358:v
2347:.
2278:e
2271:t
2264:v
2251:.
2239:.
2218:.
2194::
2173:.
2161::
2144:.
2132::
2114:.
2100::
2079:.
2057::
2035:.
2021::
2000:.
1986::
1965:.
1951::
1930:.
1918::
1901:.
1887::
1866:.
1852::
1831:.
1809::
1801::
1769:.
1747::
1739::
1712:.
1690::
1663:.
1639::
1631::
1601:.
1579::
1571::
1544:.
1522::
1495:.
1481::
1454:.
1430::
1400:.
1383:.
1371::
1348:.
1336::
1313:.
1295:.
300:)
197:)
180::
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