139:
116:
356:
349:
342:
145:
1143:
studies performed found that PCM1 was present in centriolar satellites and in electron dense granules between 70 and 100 nm in diameter. These were originally thought to be scattered only around the centrosomes, but further studies proved that PCM1 was also found throughout the cytoplasm.
1159:
was also dramatically reduced after PCM1 depletion using siRNA, overexpression of PCM1 deletion mutants and PCM1 antibody microinjection. As a result of this depletion, the radial organization of the microtubules was found to be disrupted, but did not appear to affect microtubule nucleation.
1598:
Gurling HM, Critchley H, Datta SR, McQuillin A, Blaveri E, Thirumalai S, Pimm J, Krasucki R, Kalsi G, Quested D, Lawrence J, Bass N, Choudhury K, Puri V, O'Daly O, Curtis D, Blackwood D, Muir W, Malhotra AK, Buchanan RW, Good CD, Frackowiak RS, Dolan RJ (August 2006).
1244:. If an isoleucine amino acid change in PCM1 is inherited the risk of developing schizophrenia was found to be 68% in two independent samples from south England and Scotland. This means that it may now be possible to offer very limited
1556:
Datta SR, McQuillin A, Rizig M, Blaveri E, Thirumalai S, Kalsi G, Lawrence J, Bass NJ, Puri V, Choudhury K, Pimm J, Crombie C, Fraser G, Walker N, Curtis D, Zvelebil M, Pereira A, Kandaswamy R, St Clair D, Gurling HM (December 2008).
2266:
Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry".
1697:
Li, Q; Hansen D; Killilea A; Joshi H C; Palazzo R E; Balczon R (February 2001). "Kendrin/pericentrin-B, a centrosome protein with homology to pericentrin that complexes with PCM-1".
152:
1139:. The protein appears to associate with the centrosome complex during the cell cycle. Dissociation occurs during mitosis when PCM1 is dispersed throughout the cell.
2022:"Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries"
1147:
PCM1 was shown to be essential for cell division because PCM1 antibodies cause cell-cycle arrest when microinjected into fertilized murine eggs. Targeting of
684:
665:
77:
1991:
Li Q, Hansen D, Killilea A, et al. (2001). "Kendrin/pericentrin-B, a centrosome protein with homology to pericentrin that complexes with PCM-1".
1796:
Ohata H, Fujiwara Y, Koyama K, Nakamura Y (1995). "Mapping of the human autoantigen pericentriolar material 1 (PCM1) gene to chromosome 8p21.3-p22".
1601:"Genetic Association and Brain Morphology Studies and the Chromosome 8p22 Pericentriolar Material 1 (PCM1) Gene in Susceptibility to Schizophrenia"
2233:"The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression"
1648:
Kamiya A, Tan PL, Kubo K, Engelhard C, Ishizuka K, Kubo A, Tsukita S, Pulver AE, Nakajima K, Cascella NG, Katsanis N, Sawa A (September 2008).
1335:
1192:
domain and a eukaryotic molybdopterin domain. The eukaryotic molybdopterin binding domain is currently found in only five other human genes,
1317:
2597:
2151:
Ansley SJ, Badano JL, Blacque OE, et al. (2003). "Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome".
138:
1263:), which provides a link between aberrant PCM1 and the abnormal cortical development associated with the pathology of schizophrenia.
1049:
115:
1353:
1304:
1559:"A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia"
1650:"PCM1 is recruited to the centrosome by the cooperative action of DISC1 and BBS4 and is a candidate for psychiatric illness"
1300:
2464:"Dynamic Recruitment of Nek2 Kinase to the Centrosome Involves Microtubules, PCM-1, and Localized Proteasomal Degradation"
1418:"Dynamic Recruitment of Nek2 Kinase to the Centrosome Involves Microtubules, PCM-1, and Localized Proteasomal Degradation"
1228:. In humans it is expressed above the median level of central nervous system (CNS) expression in most parts of the brain.
57:
1272:
1189:
151:
144:
2590:
729:
65:
2421:"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)"
2672:
1205:
710:
1193:
1177:
2542:"PCM1-JAK2 fusion in myeloproliferative disorders and acute erythroid leukemia with t(8;9) translocation"
2507:"The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2"
1535:
2863:
2344:
2160:
2111:
1916:
982:
2298:"Candidate tumor-suppressor genes on chromosome arm 8p in early-onset and high-grade breast cancers"
44:
2583:
1245:
1027:
1023:
1013:
1009:
1005:
1001:
978:
974:
970:
966:
962:
958:
954:
950:
946:
942:
938:
934:
930:
926:
922:
918:
914:
910:
906:
902:
898:
894:
890:
886:
882:
878:
874:
864:
860:
852:
848:
807:
803:
2184:
1784:
1169:
89:
2100:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
997:
856:
828:
799:
2563:
2528:
2493:
2450:
2407:
2372:
2319:
2284:
2254:
2219:
2176:
2139:
2086:
2043:
2008:
1979:
1944:
1891:
1856:
1813:
1776:
1722:
1714:
1679:
1630:
1580:
1496:
1447:
1398:
37:
2553:
2518:
2483:
2475:
2440:
2432:
2397:
2362:
2352:
2309:
2276:
2244:
2209:
2168:
2129:
2119:
2076:
2068:
2033:
2000:
1969:
1934:
1924:
1881:
1846:
1838:
1805:
1766:
1758:
1706:
1669:
1661:
1620:
1612:
1570:
1486:
1478:
1437:
1429:
1388:
1380:
1201:
355:
348:
341:
231:
162:
106:
1248:
to a small proportion of people with schizophrenia who are also carriers of this mutation.
1416:
Hames RS, Crookes RE, Straatman KR, Merdes A, Hayes MJ, Faragher AJ, Fry AM (April 2005).
1197:
206:
85:
1870:"Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin"
2348:
2164:
2115:
1920:
1771:
1746:
2488:
2463:
2081:
2056:
1851:
1826:
1674:
1649:
1625:
1600:
1514:
1491:
1466:
1442:
1417:
1393:
1368:
1140:
2445:
2420:
2367:
2332:
2134:
2099:
599:
594:
589:
584:
579:
574:
569:
564:
559:
554:
549:
544:
539:
534:
529:
524:
519:
514:
509:
493:
488:
483:
478:
473:
468:
463:
458:
453:
448:
443:
438:
433:
428:
423:
418:
402:
397:
2857:
1939:
1904:
1241:
384:
2575:
69:
2188:
1788:
224:
2523:
2506:
93:
2057:"Assembly of centrosomal proteins and microtubule organization depends on PCM-1"
1905:"Shotgun sequencing of the human transcriptome with ORF expressed sequence tags"
1827:"PCM-1, A 228-kD centrosome autoantigen with a distinct cell cycle distribution"
1467:"Assembly of centrosomal proteins and microtubule organization depends on PCM-1"
1369:"PCM-1, A 228-kD centrosome autoantigen with a distinct cell cycle distribution"
1340:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1322:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1225:
1221:
1173:
1136:
2402:
2385:
264:
2834:
2607:
1762:
1665:
1616:
1252:
1156:
1132:
1128:
123:
73:
1718:
2616:
2479:
2357:
2198:"Complete sequencing and characterization of 21,243 full-length human cDNAs"
1886:
1869:
1433:
629:
190:
177:
81:
2567:
2558:
2541:
2532:
2497:
2454:
2411:
2376:
2323:
2314:
2297:
2288:
2258:
2223:
2180:
2143:
2124:
2090:
2047:
2038:
2021:
2012:
1983:
1974:
1957:
1948:
1929:
1809:
1780:
1726:
1683:
1634:
1584:
1500:
1451:
2072:
2004:
1895:
1860:
1842:
1817:
1710:
1482:
1402:
1384:
1089:
1084:
2814:
2774:
2644:
1073:
774:
755:
2172:
1575:
1558:
1168:
PCM1 has four known transcripts, the longest of which has 39 exons. The
2721:
2436:
1148:
1109:
741:
696:
2280:
2824:
2819:
2809:
2804:
2799:
2794:
2789:
2784:
2729:
2639:
2634:
1185:
1181:
1127:
The PCM1 protein was originally identified by virtue of its distinct
1057:
651:
1172:
of PCM1 encodes a protein of 2024 amino acids. The protein contains
2333:"Large-scale characterization of HeLa cell nuclear phosphoproteins"
2249:
2232:
2214:
2197:
2829:
2779:
2769:
2764:
2759:
2754:
2749:
2744:
2739:
2734:
2710:
2705:
2656:
2652:
2648:
2629:
2624:
1256:
1209:
1903:
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000).
614:
610:
2839:
2700:
2695:
2680:
2662:
1276:
1260:
1152:
1116:
61:
2579:
2331:
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004).
1958:"RET/PCM-1: a novel fusion gene in papillary thyroid carcinoma"
1208:
precursor and the ATPbinding cassette, sub-family A, member 2 (
364:
2685:
1747:"Centriolar satellites: key mediators of centrosome functions"
1515:"Gene Expression Summary for Pcm1; pericentriolar material 1"
2098:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
2540:
Murati A, Gelsi-Boyer V, AdΓ©laΓ―de J, et al. (2005).
2386:"Phosphoproteomic analysis of the developing mouse brain"
2462:
Hames RS, Crookes RE, Straatman KR, et al. (2005).
2384:
Ballif BA, VillΓ©n J, Beausoleil SA, et al. (2005).
1240:
gene have been shown to cause genetic susceptibility to
214:
2419:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1868:
Engelender S, Sharp AH, Colomer V, et al. (1998).
1745:
Tollenaere M.A.X.; Mailand N; Bekker-Jensen S (2014).
1176:
regions between areas of low complexity as well as an
510:
positive regulation of intracellular protein transport
331:
2296:
Armes JE, Hammet F, de Silva M, et al. (2004).
2719:
2671:
2615:
996:
847:
821:
792:
595:
regulation of G2/M transition of mitotic cell cycle
2196:Ota T, Suzuki Y, Nishikawa T, et al. (2004).
2020:Kumar S, Connor JR, Dodds RA, et al. (2001).
1296:
1294:
1292:
525:intraciliary transport involved in cilium assembly
2505:Reiter A, Walz C, Watmore A, et al. (2005).
2231:Kim JC, Badano JL, Sibold S, et al. (2004).
161:
16:Protein-coding gene in the species Homo sapiens
1956:Corvi R, Berger N, Balczon R, Romeo G (2000).
1301:GRCm38: Ensembl release 89: ENSMUSG00000031592
2591:
1354:"Entrez Gene: PCM1 pericentriolar material 1"
8:
48:, PTC4, RET/PCM-1, pericentriolar material 1
2598:
2584:
2576:
1367:Balczon R, Bao L, Zimmer WE (March 1994).
993:
844:
625:
580:ciliary basal body-plasma membrane docking
380:
202:
101:
2557:
2522:
2487:
2444:
2401:
2366:
2356:
2313:
2248:
2213:
2133:
2123:
2080:
2037:
1973:
1938:
1928:
1885:
1850:
1770:
1673:
1624:
1574:
1490:
1441:
1392:
520:neuronal stem cell population maintenance
1288:
1259:) and Bardet-Biedl syndrome 4 protein (
18:
535:G2/M transition of mitotic cell cycle
166:
127:
122:
7:
1825:Balczon R, Bao L, Zimmer WE (1994).
1224:has been found to be highest in the
540:cytoplasmic microtubule organization
1517:. Allen Institute for Brain Science
1465:Dammermann, A.; Merdes, A. (2002).
1255:with disrupted-in-schizophrenia 1 (
555:microtubule anchoring at centrosome
545:negative regulation of neurogenesis
1538:. BioGPS - your Gene Portal System
1112:which in humans is encoded by the
818:
789:
765:
746:
720:
701:
675:
656:
560:protein localization to centrosome
336:
259:
240:
219:
14:
600:protein localization to organelle
1131:-dependent association with the
354:
347:
340:
150:
143:
137:
114:
2055:Dammermann A, Merdes A (2002).
550:interkinetic nuclear migration
365:More reference expression data
1:
2524:10.1158/0008-5472.CAN-04-4263
1536:"PCM1, Probe set 202174_s_at"
439:microtubule organizing center
135:
2337:Proc. Natl. Acad. Sci. U.S.A
2104:Proc. Natl. Acad. Sci. U.S.A
1909:Proc. Natl. Acad. Sci. U.S.A
1251:PCM1 forms a complex at the
1220:PCM1 mRNA expression in the
530:cell projection organization
1471:The Journal of Cell Biology
1200:(mitochondrial precursor),
2880:
2403:10.1074/mcp.M400085-MCP200
585:non-motile cilium assembly
494:protein-containing complex
1763:10.1007/s00018-014-1711-3
1666:10.1001/archpsyc.65.9.996
1617:10.1001/archpsyc.63.8.844
1336:"Mouse PubMed Reference:"
1318:"Human PubMed Reference:"
1102:Pericentriolar material 1
1088:
1083:
1079:
1072:
1056:
1039:
1020:
871:
840:
825:
796:
785:
772:
768:
753:
749:
740:
727:
723:
708:
704:
695:
682:
678:
663:
659:
650:
635:
628:
624:
608:
403:identical protein binding
383:
379:
362:
339:
330:
322:
271:
262:
247:
243:
213:
205:
201:
184:
171:
134:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
2673:Pericentriolar material
2480:10.1091/mbc.E04-08-0688
2358:10.1073/pnas.0404720101
1434:10.1091/mbc.E04-08-0688
1271:PCM1 has been shown to
1206:erythropoietin receptor
1050:Chr 8: 41.24 β 41.33 Mb
469:pericentriolar material
454:ciliary transition zone
2559:10.1038/sj.leu.2403879
2315:10.1038/sj.onc.1207740
2125:10.1073/pnas.242603899
2039:10.1053/joca.2001.0421
1975:10.1038/sj.onc.1203772
1930:10.1073/pnas.97.7.3491
1810:10.1006/geno.1994.1640
1194:xanthine dehydrogenase
1178:adenosine triphosphate
2390:Mol. Cell. Proteomics
2073:10.1083/jcb.200204023
2005:10.1242/jcs.114.4.797
1887:10.1093/hmg/6.13.2205
1843:10.1083/jcb.124.5.783
1711:10.1242/jcs.114.4.797
1654:Arch. Gen. Psychiatry
1605:Arch. Gen. Psychiatry
1483:10.1083/jcb.200204023
1385:10.1083/jcb.124.5.783
1232:Clinical significance
565:microtubule anchoring
1190:nuclear localization
464:centriolar satellite
168:8 A4|8 23.89 cM
129:Chromosome 8 (mouse)
2349:2004PNAS..10112130B
2173:10.1038/nature02030
2165:2003Natur.425..628A
2116:2002PNAS...9916899M
1921:2000PNAS...97.3491D
1751:Cell. Mol. Life Sci
1576:10.1038/mp.2008.128
1246:genetic counselling
1216:Tissue distribution
484:apical part of cell
2610:and its components
2437:10.1101/gr.2596504
2026:Osteoarthr. Cartil
1170:open reading frame
730:ENSMUSG00000031592
503:Biological process
419:ciliary basal body
412:Cellular component
391:Molecular function
2848:
2847:
2281:10.1021/ac035352d
2110:(26): 16899β903.
1999:(Pt 4): 797β809.
1705:(Pt 4): 797β809.
1236:Mutations in the
1099:
1098:
1095:
1094:
1068:
1067:
1035:
1034:
990:
989:
836:
835:
815:
814:
781:
780:
762:
761:
736:
735:
717:
716:
691:
690:
672:
671:
620:
619:
489:non-motile cilium
375:
374:
371:
370:
326:
325:
318:
317:
256:
255:
197:
196:
2871:
2600:
2593:
2586:
2577:
2571:
2561:
2536:
2526:
2501:
2491:
2458:
2448:
2415:
2405:
2396:(11): 1093β101.
2380:
2370:
2360:
2327:
2317:
2308:(33): 5697β702.
2292:
2262:
2252:
2227:
2217:
2192:
2159:(6958): 628β33.
2147:
2137:
2127:
2094:
2084:
2051:
2041:
2016:
1987:
1977:
1952:
1942:
1932:
1899:
1889:
1864:
1854:
1821:
1792:
1774:
1731:
1730:
1694:
1688:
1687:
1677:
1645:
1639:
1638:
1628:
1595:
1589:
1588:
1578:
1553:
1547:
1546:
1544:
1543:
1532:
1526:
1525:
1523:
1522:
1511:
1505:
1504:
1494:
1462:
1456:
1455:
1445:
1413:
1407:
1406:
1396:
1364:
1358:
1357:
1350:
1344:
1343:
1332:
1326:
1325:
1314:
1308:
1298:
1202:aldehyde oxidase
1104:, also known as
1081:
1080:
1052:
1045:
1030:
994:
985:
845:
841:RefSeq (protein)
831:
819:
810:
790:
766:
747:
721:
702:
676:
657:
626:
590:centrosome cycle
515:neuron migration
429:nuclear membrane
381:
367:
358:
351:
344:
337:
291:ventricular zone
279:genital tubercle
267:
265:Top expressed in
260:
241:
220:
203:
193:
180:
169:
154:
147:
141:
130:
118:
102:
96:
94:PCM1 - orthologs
47:
40:
19:
2879:
2878:
2874:
2873:
2872:
2870:
2869:
2868:
2854:
2853:
2851:
2849:
2844:
2715:
2667:
2611:
2604:
2574:
2539:
2504:
2468:Mol. Biol. Cell
2461:
2431:(10B): 2121β7.
2418:
2383:
2343:(33): 12130β5.
2330:
2295:
2275:(10): 2763β72.
2265:
2230:
2195:
2150:
2097:
2054:
2019:
1990:
1968:(37): 4236β42.
1955:
1902:
1880:(13): 2205β12.
1874:Hum. Mol. Genet
1867:
1824:
1795:
1744:
1740:
1738:Further reading
1735:
1734:
1696:
1695:
1691:
1660:(9): 996β1006.
1647:
1646:
1642:
1597:
1596:
1592:
1563:Mol. Psychiatry
1555:
1554:
1550:
1541:
1539:
1534:
1533:
1529:
1520:
1518:
1513:
1512:
1508:
1464:
1463:
1459:
1422:Mol. Biol. Cell
1415:
1414:
1410:
1366:
1365:
1361:
1352:
1351:
1347:
1334:
1333:
1329:
1316:
1315:
1311:
1299:
1290:
1285:
1269:
1234:
1218:
1198:sulfite oxidase
1166:
1125:
1090:View/Edit Mouse
1085:View/Edit Human
1048:
1043:
1040:Location (UCSC)
1026:
1022:
1016:
1012:
1008:
1004:
1000:
981:
977:
973:
969:
965:
961:
957:
953:
949:
945:
941:
937:
933:
929:
925:
921:
917:
913:
909:
905:
901:
897:
893:
889:
885:
881:
877:
873:
867:
863:
859:
855:
851:
827:
806:
802:
798:
711:ENSG00000078674
604:
575:cilium assembly
570:social behavior
498:
424:cell projection
407:
398:protein binding
363:
353:
352:
346:
345:
314:
309:
305:
303:ascending aorta
301:
297:
293:
289:
285:
281:
277:
263:
252:
188:
175:
167:
157:
156:
155:
148:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
2877:
2875:
2867:
2866:
2856:
2855:
2846:
2845:
2843:
2842:
2837:
2832:
2827:
2822:
2817:
2812:
2807:
2802:
2797:
2792:
2787:
2782:
2777:
2772:
2767:
2762:
2757:
2752:
2747:
2742:
2737:
2732:
2726:
2724:
2717:
2716:
2714:
2713:
2708:
2703:
2698:
2693:
2688:
2683:
2677:
2675:
2669:
2668:
2666:
2665:
2660:
2642:
2637:
2632:
2627:
2621:
2619:
2613:
2612:
2605:
2603:
2602:
2595:
2588:
2580:
2573:
2572:
2537:
2502:
2474:(4): 1711β24.
2459:
2416:
2381:
2328:
2293:
2263:
2250:10.1038/ng1352
2228:
2215:10.1038/ng1285
2193:
2148:
2095:
2052:
2017:
1988:
1953:
1900:
1865:
1822:
1793:
1741:
1739:
1736:
1733:
1732:
1689:
1640:
1590:
1548:
1527:
1506:
1477:(2): 255β266.
1457:
1428:(4): 1711β24.
1408:
1359:
1345:
1327:
1309:
1287:
1286:
1284:
1281:
1268:
1265:
1233:
1230:
1217:
1214:
1165:
1164:Gene structure
1162:
1141:Immunolabeling
1124:
1121:
1097:
1096:
1093:
1092:
1087:
1077:
1076:
1070:
1069:
1066:
1065:
1063:
1061:
1054:
1053:
1046:
1041:
1037:
1036:
1033:
1032:
1018:
1017:
991:
988:
987:
983:NP_001302436.1
869:
868:
842:
838:
837:
834:
833:
823:
822:
816:
813:
812:
794:
793:
787:
783:
782:
779:
778:
770:
769:
763:
760:
759:
751:
750:
744:
738:
737:
734:
733:
725:
724:
718:
715:
714:
706:
705:
699:
693:
692:
689:
688:
680:
679:
673:
670:
669:
661:
660:
654:
648:
647:
642:
637:
633:
632:
622:
621:
618:
617:
606:
605:
603:
602:
597:
592:
587:
582:
577:
572:
567:
562:
557:
552:
547:
542:
537:
532:
527:
522:
517:
512:
506:
504:
500:
499:
497:
496:
491:
486:
481:
476:
471:
466:
461:
456:
451:
446:
441:
436:
431:
426:
421:
415:
413:
409:
408:
406:
405:
400:
394:
392:
388:
387:
377:
376:
373:
372:
369:
368:
360:
359:
334:
328:
327:
324:
323:
320:
319:
316:
315:
313:
312:
308:
304:
300:
296:
292:
288:
284:
283:tail of embryo
280:
276:
272:
269:
268:
257:
254:
253:
251:
248:
245:
244:
237:
236:
228:
217:
211:
210:
207:RNA expression
199:
198:
195:
194:
186:
182:
181:
173:
170:
165:
159:
158:
149:
142:
136:
132:
131:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
2876:
2865:
2862:
2861:
2859:
2852:
2841:
2838:
2836:
2833:
2831:
2828:
2826:
2823:
2821:
2818:
2816:
2813:
2811:
2808:
2806:
2803:
2801:
2798:
2796:
2793:
2791:
2788:
2786:
2783:
2781:
2778:
2776:
2773:
2771:
2768:
2766:
2763:
2761:
2758:
2756:
2753:
2751:
2748:
2746:
2743:
2741:
2738:
2736:
2733:
2731:
2728:
2727:
2725:
2723:
2718:
2712:
2709:
2707:
2704:
2702:
2699:
2697:
2694:
2692:
2689:
2687:
2684:
2682:
2679:
2678:
2676:
2674:
2670:
2664:
2661:
2658:
2654:
2650:
2646:
2643:
2641:
2638:
2636:
2633:
2631:
2628:
2626:
2623:
2622:
2620:
2618:
2614:
2609:
2601:
2596:
2594:
2589:
2587:
2582:
2581:
2578:
2569:
2565:
2560:
2555:
2552:(9): 1692β6.
2551:
2547:
2543:
2538:
2534:
2530:
2525:
2520:
2517:(7): 2662β7.
2516:
2512:
2508:
2503:
2499:
2495:
2490:
2485:
2481:
2477:
2473:
2469:
2465:
2460:
2456:
2452:
2447:
2442:
2438:
2434:
2430:
2426:
2422:
2417:
2413:
2409:
2404:
2399:
2395:
2391:
2387:
2382:
2378:
2374:
2369:
2364:
2359:
2354:
2350:
2346:
2342:
2338:
2334:
2329:
2325:
2321:
2316:
2311:
2307:
2303:
2299:
2294:
2290:
2286:
2282:
2278:
2274:
2270:
2264:
2260:
2256:
2251:
2246:
2243:(5): 462β70.
2242:
2238:
2234:
2229:
2225:
2221:
2216:
2211:
2207:
2203:
2199:
2194:
2190:
2186:
2182:
2178:
2174:
2170:
2166:
2162:
2158:
2154:
2149:
2145:
2141:
2136:
2131:
2126:
2121:
2117:
2113:
2109:
2105:
2101:
2096:
2092:
2088:
2083:
2078:
2074:
2070:
2067:(2): 255β66.
2066:
2062:
2058:
2053:
2049:
2045:
2040:
2035:
2032:(7): 641β53.
2031:
2027:
2023:
2018:
2014:
2010:
2006:
2002:
1998:
1994:
1989:
1985:
1981:
1976:
1971:
1967:
1963:
1959:
1954:
1950:
1946:
1941:
1936:
1931:
1926:
1922:
1918:
1915:(7): 3491β6.
1914:
1910:
1906:
1901:
1897:
1893:
1888:
1883:
1879:
1875:
1871:
1866:
1862:
1858:
1853:
1848:
1844:
1840:
1837:(5): 783β93.
1836:
1832:
1828:
1823:
1819:
1815:
1811:
1807:
1803:
1799:
1794:
1790:
1786:
1782:
1778:
1773:
1768:
1764:
1760:
1756:
1752:
1748:
1743:
1742:
1737:
1728:
1724:
1720:
1716:
1712:
1708:
1704:
1700:
1693:
1690:
1685:
1681:
1676:
1671:
1667:
1663:
1659:
1655:
1651:
1644:
1641:
1636:
1632:
1627:
1622:
1618:
1614:
1611:(8): 844β54.
1610:
1606:
1602:
1594:
1591:
1586:
1582:
1577:
1572:
1569:(6): 615β28.
1568:
1564:
1560:
1552:
1549:
1537:
1531:
1528:
1516:
1510:
1507:
1502:
1498:
1493:
1488:
1484:
1480:
1476:
1472:
1468:
1461:
1458:
1453:
1449:
1444:
1439:
1435:
1431:
1427:
1423:
1419:
1412:
1409:
1404:
1400:
1395:
1390:
1386:
1382:
1379:(5): 783β93.
1378:
1374:
1370:
1363:
1360:
1355:
1349:
1346:
1341:
1337:
1331:
1328:
1323:
1319:
1313:
1310:
1306:
1302:
1297:
1295:
1293:
1289:
1282:
1280:
1278:
1274:
1266:
1264:
1262:
1258:
1254:
1249:
1247:
1243:
1242:schizophrenia
1239:
1231:
1229:
1227:
1223:
1215:
1213:
1211:
1207:
1203:
1199:
1195:
1191:
1187:
1183:
1179:
1175:
1171:
1163:
1161:
1158:
1154:
1150:
1145:
1142:
1138:
1134:
1130:
1122:
1120:
1118:
1115:
1111:
1107:
1103:
1091:
1086:
1082:
1078:
1075:
1071:
1064:
1062:
1059:
1055:
1051:
1047:
1042:
1038:
1031:
1029:
1025:
1019:
1015:
1011:
1007:
1003:
999:
995:
992:
986:
984:
980:
976:
972:
968:
964:
960:
956:
952:
948:
944:
940:
936:
932:
928:
924:
920:
916:
912:
908:
904:
900:
896:
892:
888:
884:
880:
876:
870:
866:
862:
858:
854:
850:
846:
843:
839:
832:
830:
824:
820:
817:
811:
809:
805:
801:
795:
791:
788:
786:RefSeq (mRNA)
784:
777:
776:
771:
767:
764:
758:
757:
752:
748:
745:
743:
739:
732:
731:
726:
722:
719:
713:
712:
707:
703:
700:
698:
694:
687:
686:
681:
677:
674:
668:
667:
662:
658:
655:
653:
649:
646:
643:
641:
638:
634:
631:
627:
623:
616:
612:
607:
601:
598:
596:
593:
591:
588:
586:
583:
581:
578:
576:
573:
571:
568:
566:
563:
561:
558:
556:
553:
551:
548:
546:
543:
541:
538:
536:
533:
531:
528:
526:
523:
521:
518:
516:
513:
511:
508:
507:
505:
502:
501:
495:
492:
490:
487:
485:
482:
480:
477:
475:
472:
470:
467:
465:
462:
460:
457:
455:
452:
450:
447:
445:
442:
440:
437:
435:
432:
430:
427:
425:
422:
420:
417:
416:
414:
411:
410:
404:
401:
399:
396:
395:
393:
390:
389:
386:
385:Gene ontology
382:
378:
366:
361:
357:
350:
343:
338:
335:
333:
329:
321:
310:
306:
302:
298:
294:
290:
286:
282:
278:
274:
273:
270:
266:
261:
258:
249:
246:
242:
239:
238:
235:
233:
229:
227:
226:
222:
221:
218:
216:
212:
208:
204:
200:
192:
187:
183:
179:
174:
164:
160:
153:
146:
140:
133:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
2850:
2690:
2549:
2545:
2514:
2510:
2471:
2467:
2428:
2424:
2393:
2389:
2340:
2336:
2305:
2301:
2272:
2268:
2240:
2236:
2205:
2201:
2156:
2152:
2107:
2103:
2064:
2061:J. Cell Biol
2060:
2029:
2025:
1996:
1992:
1965:
1961:
1912:
1908:
1877:
1873:
1834:
1831:J. Cell Biol
1830:
1804:(2): 404β6.
1801:
1797:
1757:(1): 11β23.
1754:
1750:
1702:
1698:
1692:
1657:
1653:
1643:
1608:
1604:
1593:
1566:
1562:
1551:
1540:. Retrieved
1530:
1519:. Retrieved
1509:
1474:
1470:
1460:
1425:
1421:
1411:
1376:
1373:J. Cell Biol
1372:
1362:
1348:
1339:
1330:
1321:
1312:
1270:
1267:Interactions
1250:
1237:
1235:
1219:
1167:
1146:
1137:microtubules
1135:complex and
1126:
1113:
1105:
1101:
1100:
1028:NP_001390754
1024:NP_001390753
1021:
1014:NP_001390752
1010:NP_001390749
1006:NP_001390748
1002:NP_001390746
979:NP_001339589
975:NP_001339588
971:NP_001339587
967:NP_001339586
963:NP_001339585
959:NP_001339584
955:NP_001339583
951:NP_001339582
947:NP_001339581
943:NP_001339580
939:NP_001339579
935:NP_001339578
931:NP_001339577
927:NP_001339576
923:NP_001339575
919:NP_001339574
915:NP_001339573
911:NP_001339572
907:NP_001339571
903:NP_001339570
899:NP_001339569
895:NP_001339568
891:NP_001339567
887:NP_001339566
883:NP_001339565
879:NP_001339564
875:NP_001339563
872:
865:NP_001339562
861:NP_001339561
853:NP_001302437
849:NP_001302436
826:
808:NM_001315508
804:NM_001315507
797:
773:
754:
728:
709:
683:
664:
644:
639:
449:cytoskeleton
311:otic vesicle
299:otic placode
275:spermatocyte
230:
223:
53:External IDs
2864:Human genes
2208:(1): 40β5.
1993:J. Cell Sci
1699:J. Cell Sci
1226:hippocampus
1222:mouse brain
1174:coiled coil
1153:pericentrin
189:41,332,344
176:41,239,752
31:Identifiers
2617:Centrioles
2608:centrosome
2511:Cancer Res
2425:Genome Res
2269:Anal. Chem
2237:Nat. Genet
2202:Nat. Genet
1542:2009-04-30
1521:2009-04-30
1307:, May 2017
1283:References
1253:centrosome
1188:domain, a
1133:centrosome
1129:cell cycle
459:centrosome
234:(ortholog)
74:HomoloGene
1719:0021-9533
998:NP_076151
857:NP_006188
829:NM_023662
800:NM_006197
630:Orthologs
474:cytoplasm
444:centriole
295:spermatid
82:GeneCards
2858:Category
2722:proteins
2645:Centrins
2568:16034466
2546:Leukemia
2533:15805263
2498:15659651
2455:15489334
2412:15345747
2377:15302935
2324:15184884
2302:Oncogene
2289:15144186
2259:15107855
2224:14702039
2181:14520415
2144:12477932
2091:12403812
2048:11597177
2013:11171385
1984:10980597
1962:Oncogene
1949:10737800
1798:Genomics
1781:25173771
1772:11114028
1727:11171385
1684:18762586
1635:16894060
1585:19048012
1501:12403812
1452:15659651
1303:–
1273:interact
1123:Function
1074:Wikidata
609:Sources:
434:membrane
2489:1073654
2345:Bibcode
2189:4310157
2161:Bibcode
2112:Bibcode
2082:2173044
1917:Bibcode
1896:9361024
1861:8120099
1852:2119948
1818:7698772
1789:2243856
1675:2727928
1626:2634866
1492:2173044
1443:1073654
1403:8120099
1394:2119948
1305:Ensembl
1149:centrin
1110:protein
1108:, is a
742:UniProt
697:Ensembl
636:Species
615:QuickGO
479:cytosol
287:saccule
209:pattern
70:1277958
38:Aliases
2825:CEP350
2820:CEP250
2815:CEP215
2810:CEP192
2805:CEP170
2800:CEP164
2795:CEP152
2790:CEP135
2785:CEP120
2730:CCP110
2720:other
2640:CEP104
2635:CNTROB
2566:
2531:
2496:
2486:
2453:
2446:528928
2443:
2410:
2375:
2368:514446
2365:
2322:
2287:
2257:
2222:
2187:
2179:
2153:Nature
2142:
2135:139241
2132:
2089:
2079:
2046:
2011:
1982:
1947:
1937:
1894:
1859:
1849:
1816:
1787:
1779:
1769:
1725:
1717:
1682:
1672:
1633:
1623:
1583:
1499:
1489:
1450:
1440:
1401:
1391:
1186:GTPase
1157:ninein
1060:search
1058:PubMed
775:Q9R0L6
756:Q15154
652:Entrez
332:BioGPS
307:zygote
62:600299
2830:CNTRL
2780:CEP97
2775:CEP90
2770:CEP78
2765:CEP76
2760:CEP72
2755:CEP70
2750:CEP68
2745:CEP63
2740:CEP57
2735:CEP55
2711:TUBE1
2706:TNKS2
2657:CETN3
2653:CETN2
2649:CETN1
2630:CENPJ
2625:SASS6
2185:S2CID
1940:16267
1785:S2CID
1275:with
1257:DISC1
1210:ABCA2
685:18536
645:Mouse
640:Human
611:Amigo
232:Mouse
225:Human
172:Start
107:Mouse
2840:NINL
2701:TNKS
2696:PCNT
2691:PCM1
2681:BBS4
2663:SFI1
2655:and
2606:The
2564:PMID
2529:PMID
2494:PMID
2451:PMID
2408:PMID
2373:PMID
2320:PMID
2285:PMID
2255:PMID
2220:PMID
2177:PMID
2140:PMID
2087:PMID
2044:PMID
2009:PMID
1980:PMID
1945:PMID
1892:PMID
1857:PMID
1814:PMID
1777:PMID
1723:PMID
1715:ISSN
1680:PMID
1631:PMID
1581:PMID
1497:PMID
1448:PMID
1399:PMID
1277:PCNT
1261:BBS4
1238:PCM1
1184:) /
1155:and
1117:gene
1114:PCM1
1106:PCM1
666:5108
215:Bgee
163:Band
124:Chr.
86:PCM1
78:4518
58:OMIM
45:PCM1
22:PCM1
2835:NIN
2686:Lck
2554:doi
2519:doi
2484:PMC
2476:doi
2441:PMC
2433:doi
2398:doi
2363:PMC
2353:doi
2341:101
2310:doi
2277:doi
2245:doi
2210:doi
2169:doi
2157:425
2130:PMC
2120:doi
2077:PMC
2069:doi
2065:159
2034:doi
2001:doi
1997:114
1970:doi
1935:PMC
1925:doi
1882:doi
1847:PMC
1839:doi
1835:124
1806:doi
1767:PMC
1759:doi
1707:doi
1703:114
1670:PMC
1662:doi
1621:PMC
1613:doi
1571:doi
1487:PMC
1479:doi
1475:159
1438:PMC
1430:doi
1389:PMC
1381:doi
1377:124
1212:).
1182:ATP
1044:n/a
250:n/a
185:End
90:OMA
66:MGI
2860::
2651:,
2562:.
2550:19
2548:.
2544:.
2527:.
2515:65
2513:.
2509:.
2492:.
2482:.
2472:16
2470:.
2466:.
2449:.
2439:.
2429:14
2427:.
2423:.
2406:.
2392:.
2388:.
2371:.
2361:.
2351:.
2339:.
2335:.
2318:.
2306:23
2304:.
2300:.
2283:.
2273:76
2271:.
2253:.
2241:36
2239:.
2235:.
2218:.
2206:36
2204:.
2200:.
2183:.
2175:.
2167:.
2155:.
2138:.
2128:.
2118:.
2108:99
2106:.
2102:.
2085:.
2075:.
2063:.
2059:.
2042:.
2028:.
2024:.
2007:.
1995:.
1978:.
1966:19
1964:.
1960:.
1943:.
1933:.
1923:.
1913:97
1911:.
1907:.
1890:.
1876:.
1872:.
1855:.
1845:.
1833:.
1829:.
1812:.
1802:24
1800:.
1783:.
1775:.
1765:.
1755:72
1753:.
1749:.
1721:.
1713:.
1701:.
1678:.
1668:.
1658:65
1656:.
1652:.
1629:.
1619:.
1609:63
1607:.
1603:.
1579:.
1567:15
1565:.
1561:.
1495:.
1485:.
1473:.
1469:.
1446:.
1436:.
1426:16
1424:.
1420:.
1397:.
1387:.
1375:.
1371:.
1338:.
1320:.
1291:^
1279:.
1204:,
1196:,
1151:,
1119:.
613:/
191:bp
178:bp
88:;
84::
80:;
76::
72:;
68::
64:;
60::
2659:)
2647:(
2599:e
2592:t
2585:v
2570:.
2556::
2535:.
2521::
2500:.
2478::
2457:.
2435::
2414:.
2400::
2394:3
2379:.
2355::
2347::
2326:.
2312::
2291:.
2279::
2261:.
2247::
2226:.
2212::
2191:.
2171::
2163::
2146:.
2122::
2114::
2093:.
2071::
2050:.
2036::
2030:9
2015:.
2003::
1986:.
1972::
1951:.
1927::
1919::
1898:.
1884::
1878:6
1863:.
1841::
1820:.
1808::
1791:.
1761::
1729:.
1709::
1686:.
1664::
1637:.
1615::
1587:.
1573::
1545:.
1524:.
1503:.
1481::
1454:.
1432::
1405:.
1383::
1356:.
1342:.
1324:.
1180:(
109:)
92::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.