253:
230:
127:
152:
259:
158:
1506:
266:
165:
1307:"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment"
1463:"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries"
683:
664:
88:
971:
found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI
1575:
1551:
1056:
1570:
1038:
1229:"Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge"
252:
883:
890:
229:
1077:
1025:
1004:
151:
126:
1021:
1428:"Endoplasmic reticulum localization of Gaa1 and PIG-T, subunits of the glycosylphosphatidylinositol transamidase complex"
1141:"Structural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complex"
1000:
964:
68:
265:
164:
1544:
258:
157:
728:
76:
1264:"Human PIG-U and yeast Cdc91p are the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins"
1385:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
709:
1537:
976:
140:
1187:
1098:"PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8"
55:
100:
1176:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
866:
845:
819:
798:
1484:
1449:
1414:
1371:
1336:
1293:
1250:
1215:
1162:
1127:
48:
1521:
1474:
1439:
1404:
1396:
1361:
1326:
1318:
1283:
1275:
1240:
1205:
1195:
1152:
1117:
1109:
345:
276:
220:
175:
320:
96:
1191:
1409:
1384:
1331:
1306:
1288:
1263:
1210:
1175:
1122:
1097:
598:
593:
577:
572:
567:
562:
557:
541:
536:
1564:
1517:
523:
80:
972:
957:
338:
117:
104:
1061:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1043:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1113:
421:
17:
1479:
1462:
968:
237:
134:
84:
1350:"Complete sequencing and characterization of 21,243 full-length human cDNAs"
1279:
1078:"Entrez Gene: PIGS phosphatidylinositol glycan anchor biosynthesis, class S"
628:
481:
359:
304:
291:
203:
190:
92:
1488:
1453:
1444:
1427:
1418:
1375:
1340:
1297:
1254:
1245:
1228:
1219:
1200:
1166:
1157:
1140:
1131:
930:
925:
914:
773:
754:
59:, phosphatidylinositol glycan anchor biosynthesis class S, GPIBD18, DEE95
1400:
1322:
979:, by catalyzing the transfer of fully assembled GPI units to proteins.
740:
695:
946:
898:
650:
1505:
1366:
1349:
613:
609:
1513:
953:
72:
956:. This gene encodes a protein that is involved in GPI-anchor
1174:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
1139:
Vainauskas S, Maeda Y, Kurniawan H, et al. (2002).
328:
1525:
1383:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
493:
1227:Ohishi K, Nagamune K, Maeda Y, Kinoshita T (2003).
859:
838:
812:
791:
1461:Otsuki T, Ota T, Nishikawa T, et al. (2007).
1348:Ota T, Suzuki Y, Nishikawa T, et al. (2004).
1305:Clark HF, Gurney AL, Abaya E, et al. (2003).
1017:
1015:
1013:
996:
994:
992:
975:. GPI transamidase mediates GPI anchoring in the
275:
174:
1262:Hong Y, Ohishi K, Kang JY, et al. (2004).
27:Protein-coding gene in the species Homo sapiens
1022:GRCm38: Ensembl release 89: ENSMUSG00000041958
1545:
8:
1001:GRCh38: Ensembl release 89: ENSG00000087111
1552:
1538:
624:
519:
316:
215:
112:
1478:
1443:
1408:
1365:
1330:
1287:
1244:
1209:
1199:
1156:
1121:
1072:
1070:
1096:Ohishi K, Inoue N, Kinoshita T (2001).
988:
29:
280:
241:
236:
179:
138:
133:
7:
1502:
1500:
594:attachment of GPI anchor to protein
1524:. You can help Knowledge (XXG) by
856:
835:
809:
788:
764:
745:
719:
700:
674:
655:
498:
432:choroid plexus of fourth ventricle
416:
354:
333:
25:
949:that in humans is encoded by the
1504:
943:GPI transamidase component PIG-S
542:GPI-anchor transamidase activity
264:
257:
251:
228:
163:
156:
150:
125:
1426:Vainauskas S, Menon AK (2005).
599:GPI anchor biosynthetic process
563:GPI-anchor transamidase complex
1576:Human chromosome 17 gene stubs
568:endoplasmic reticulum membrane
558:integral component of membrane
482:More reference expression data
402:right hemisphere of cerebellum
1:
249:
148:
1571:Genes on human chromosome 17
1180:Proc. Natl. Acad. Sci. U.S.A
965:glycosylphosphatidylinositol
370:stromal cell of endometrium
1592:
1499:
382:mucosa of transverse colon
1057:"Mouse PubMed Reference:"
1039:"Human PubMed Reference:"
929:
924:
920:
913:
897:
878:
863:
842:
831:
816:
795:
784:
771:
767:
752:
748:
739:
726:
722:
707:
703:
694:
681:
677:
662:
658:
649:
634:
627:
623:
607:
522:
518:
506:
501:
492:
479:
428:
419:
366:
357:
327:
319:
315:
298:
285:
248:
227:
218:
214:
197:
184:
147:
124:
115:
111:
66:
63:
53:
46:
41:
37:
32:
1114:10.1093/emboj/20.15.4088
891:Chr 11: 78.22 – 78.23 Mb
884:Chr 17: 28.55 – 28.57 Mb
1480:10.1093/dnares/12.2.117
1280:10.1091/mbc.E02-12-0794
1445:10.1074/jbc.M414253200
1246:10.1074/jbc.M300586200
1201:10.1073/pnas.242603899
1158:10.1074/jbc.M205402200
977:endoplasmic reticulum
578:endoplasmic reticulum
448:stroma of bone marrow
243:Chromosome 11 (mouse)
141:Chromosome 17 (human)
1192:2002PNAS...9916899M
378:islet of Langerhans
1512:This article on a
1401:10.1101/gr.2596504
1323:10.1101/gr.1293003
967:(GPI) anchor is a
729:ENSMUSG00000041958
587:Biological process
551:Cellular component
530:Molecular function
1533:
1532:
1186:(26): 16899–903.
940:
939:
936:
935:
909:
908:
874:
873:
853:
852:
827:
826:
806:
805:
780:
779:
761:
760:
735:
734:
716:
715:
690:
689:
671:
670:
619:
618:
514:
513:
510:
509:
488:
487:
475:
474:
464:lactiferous gland
444:perirhinal cortex
440:entorhinal cortex
413:
412:
311:
310:
210:
209:
16:(Redirected from
1583:
1554:
1547:
1540:
1508:
1501:
1492:
1482:
1457:
1447:
1422:
1412:
1379:
1369:
1344:
1334:
1301:
1291:
1258:
1248:
1239:(16): 13959–67.
1223:
1213:
1203:
1170:
1160:
1151:(34): 30535–42.
1135:
1125:
1082:
1081:
1074:
1065:
1064:
1053:
1047:
1046:
1035:
1029:
1019:
1008:
998:
922:
921:
893:
886:
869:
857:
848:
836:
832:RefSeq (protein)
822:
810:
801:
789:
765:
746:
720:
701:
675:
656:
625:
520:
499:
484:
468:genital tubercle
424:
422:Top expressed in
417:
362:
360:Top expressed in
355:
334:
317:
307:
294:
283:
268:
261:
255:
244:
232:
216:
206:
193:
182:
167:
160:
154:
143:
129:
113:
107:
105:PIGS - orthologs
58:
51:
30:
21:
1591:
1590:
1586:
1585:
1584:
1582:
1581:
1580:
1561:
1560:
1559:
1558:
1497:
1495:
1460:
1438:(16): 16402–9.
1425:
1395:(10B): 2121–7.
1382:
1347:
1317:(10): 2265–70.
1304:
1268:Mol. Biol. Cell
1261:
1226:
1173:
1138:
1108:(15): 4088–98.
1095:
1091:
1089:Further reading
1086:
1085:
1076:
1075:
1068:
1055:
1054:
1050:
1037:
1036:
1032:
1020:
1011:
999:
990:
985:
931:View/Edit Mouse
926:View/Edit Human
889:
882:
879:Location (UCSC)
865:
844:
818:
797:
710:ENSG00000087111
603:
582:
546:
537:protein binding
480:
471:
466:
462:
458:
456:muscle of thigh
454:
450:
446:
442:
438:
434:
420:
409:
404:
400:
396:
392:
388:
384:
380:
376:
372:
358:
302:
289:
281:
271:
270:
269:
262:
242:
219:Gene location (
201:
188:
180:
170:
169:
168:
161:
139:
116:Gene location (
67:
54:
47:
28:
23:
22:
18:PIGS (genetics)
15:
12:
11:
5:
1589:
1587:
1579:
1578:
1573:
1563:
1562:
1557:
1556:
1549:
1542:
1534:
1531:
1530:
1509:
1494:
1493:
1458:
1423:
1380:
1367:10.1038/ng1285
1345:
1302:
1259:
1224:
1171:
1136:
1092:
1090:
1087:
1084:
1083:
1066:
1048:
1030:
1009:
987:
986:
984:
981:
938:
937:
934:
933:
928:
918:
917:
911:
910:
907:
906:
904:
902:
895:
894:
887:
880:
876:
875:
872:
871:
861:
860:
854:
851:
850:
840:
839:
833:
829:
828:
825:
824:
814:
813:
807:
804:
803:
793:
792:
786:
782:
781:
778:
777:
769:
768:
762:
759:
758:
750:
749:
743:
737:
736:
733:
732:
724:
723:
717:
714:
713:
705:
704:
698:
692:
691:
688:
687:
679:
678:
672:
669:
668:
660:
659:
653:
647:
646:
641:
636:
632:
631:
621:
620:
617:
616:
605:
604:
602:
601:
596:
590:
588:
584:
583:
581:
580:
575:
570:
565:
560:
554:
552:
548:
547:
545:
544:
539:
533:
531:
527:
526:
516:
515:
512:
511:
508:
507:
504:
503:
496:
490:
489:
486:
485:
477:
476:
473:
472:
470:
469:
465:
461:
457:
453:
449:
445:
441:
437:
433:
429:
426:
425:
414:
411:
410:
408:
407:
403:
399:
398:left ventricle
395:
391:
387:
383:
379:
375:
371:
367:
364:
363:
351:
350:
342:
331:
325:
324:
321:RNA expression
313:
312:
309:
308:
300:
296:
295:
287:
284:
279:
273:
272:
263:
256:
250:
246:
245:
240:
234:
233:
225:
224:
212:
211:
208:
207:
199:
195:
194:
186:
183:
178:
172:
171:
162:
155:
149:
145:
144:
137:
131:
130:
122:
121:
109:
108:
65:
61:
60:
52:
44:
43:
39:
38:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1588:
1577:
1574:
1572:
1569:
1568:
1566:
1555:
1550:
1548:
1543:
1541:
1536:
1535:
1529:
1527:
1523:
1519:
1518:chromosome 17
1515:
1510:
1507:
1503:
1498:
1490:
1486:
1481:
1476:
1473:(2): 117–26.
1472:
1468:
1464:
1459:
1455:
1451:
1446:
1441:
1437:
1433:
1432:J. Biol. Chem
1429:
1424:
1420:
1416:
1411:
1406:
1402:
1398:
1394:
1390:
1386:
1381:
1377:
1373:
1368:
1363:
1359:
1355:
1351:
1346:
1342:
1338:
1333:
1328:
1324:
1320:
1316:
1312:
1308:
1303:
1299:
1295:
1290:
1285:
1281:
1277:
1274:(5): 1780–9.
1273:
1269:
1265:
1260:
1256:
1252:
1247:
1242:
1238:
1234:
1233:J. Biol. Chem
1230:
1225:
1221:
1217:
1212:
1207:
1202:
1197:
1193:
1189:
1185:
1181:
1177:
1172:
1168:
1164:
1159:
1154:
1150:
1146:
1145:J. Biol. Chem
1142:
1137:
1133:
1129:
1124:
1119:
1115:
1111:
1107:
1103:
1099:
1094:
1093:
1088:
1079:
1073:
1071:
1067:
1062:
1058:
1052:
1049:
1044:
1040:
1034:
1031:
1027:
1023:
1018:
1016:
1014:
1010:
1006:
1002:
997:
995:
993:
989:
982:
980:
978:
974:
970:
966:
961:
959:
955:
952:
948:
944:
932:
927:
923:
919:
916:
912:
905:
903:
900:
896:
892:
888:
885:
881:
877:
870:
868:
862:
858:
855:
849:
847:
841:
837:
834:
830:
823:
821:
815:
811:
808:
802:
800:
794:
790:
787:
785:RefSeq (mRNA)
783:
776:
775:
770:
766:
763:
757:
756:
751:
747:
744:
742:
738:
731:
730:
725:
721:
718:
712:
711:
706:
702:
699:
697:
693:
686:
685:
680:
676:
673:
667:
666:
661:
657:
654:
652:
648:
645:
642:
640:
637:
633:
630:
626:
622:
615:
611:
606:
600:
597:
595:
592:
591:
589:
586:
585:
579:
576:
574:
571:
569:
566:
564:
561:
559:
556:
555:
553:
550:
549:
543:
540:
538:
535:
534:
532:
529:
528:
525:
524:Gene ontology
521:
517:
505:
500:
497:
495:
491:
483:
478:
467:
463:
459:
455:
451:
447:
443:
439:
435:
431:
430:
427:
423:
418:
415:
405:
401:
397:
393:
389:
385:
381:
377:
373:
369:
368:
365:
361:
356:
353:
352:
349:
347:
343:
341:
340:
336:
335:
332:
330:
326:
322:
318:
314:
306:
301:
297:
293:
288:
282:11|11 B5
278:
274:
267:
260:
254:
247:
239:
235:
231:
226:
222:
217:
213:
205:
200:
196:
192:
187:
177:
173:
166:
159:
153:
146:
142:
136:
132:
128:
123:
119:
114:
110:
106:
102:
98:
94:
90:
86:
82:
78:
74:
70:
62:
57:
50:
45:
40:
36:
31:
19:
1526:expanding it
1511:
1496:
1470:
1466:
1435:
1431:
1392:
1388:
1357:
1353:
1314:
1310:
1271:
1267:
1236:
1232:
1183:
1179:
1148:
1144:
1105:
1101:
1060:
1051:
1042:
1033:
973:transamidase
962:
958:biosynthesis
950:
942:
941:
864:
843:
817:
796:
772:
753:
727:
708:
682:
663:
643:
638:
436:spermatocyte
344:
337:
64:External IDs
1360:(1): 40–5.
460:granulocyte
374:granulocyte
303:78,233,608
290:78,219,241
202:28,571,794
189:28,553,383
42:Identifiers
1565:Categories
1389:Genome Res
1354:Nat. Genet
1311:Genome Res
1028:, May 2017
1007:, May 2017
983:References
969:glycolipid
348:(ortholog)
85:HomoloGene
1516:on human
867:NP_958808
846:NP_149975
820:NM_201406
799:NM_033198
629:Orthologs
93:GeneCards
1489:16303743
1454:15713669
1419:15489334
1376:14702039
1341:12975309
1298:12802054
1255:12582175
1220:12477932
1167:12052837
1132:11483512
1024:–
1003:–
915:Wikidata
608:Sources:
573:membrane
394:monocyte
390:duodenum
1467:DNA Res
1188:Bibcode
1026:Ensembl
1005:Ensembl
741:UniProt
696:Ensembl
635:Species
614:QuickGO
323:pattern
181:17q11.2
81:2687325
49:Aliases
1487:
1452:
1417:
1410:528928
1407:
1374:
1339:
1332:403697
1329:
1296:
1289:165076
1286:
1253:
1218:
1211:139241
1208:
1165:
1130:
1123:149153
1120:
1102:EMBO J
947:enzyme
945:is an
901:search
899:PubMed
774:Q6PD26
755:Q96S52
684:276846
651:Entrez
494:BioGPS
386:rectum
73:610271
1520:is a
665:94005
644:Mouse
639:Human
610:Amigo
406:blood
346:Mouse
339:Human
286:Start
221:Mouse
185:Start
118:Human
89:41963
1522:stub
1514:gene
1485:PMID
1450:PMID
1415:PMID
1372:PMID
1337:PMID
1294:PMID
1251:PMID
1216:PMID
1163:PMID
1128:PMID
963:The
954:gene
951:PIGS
452:lens
329:Bgee
277:Band
238:Chr.
176:Band
135:Chr.
97:PIGS
69:OMIM
56:PIGS
33:PIGS
1475:doi
1440:doi
1436:280
1405:PMC
1397:doi
1362:doi
1327:PMC
1319:doi
1284:PMC
1276:doi
1241:doi
1237:278
1206:PMC
1196:doi
1153:doi
1149:277
1118:PMC
1110:doi
960:.
502:n/a
299:End
198:End
101:OMA
77:MGI
1567::
1483:.
1471:12
1469:.
1465:.
1448:.
1434:.
1430:.
1413:.
1403:.
1393:14
1391:.
1387:.
1370:.
1358:36
1356:.
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