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PRKAB2

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346: 323: 220: 245: 2172: 597: 29: 352: 251: 4349: 4369: 55: 1125:(AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus 1432:
Harvard C, Strong E, Mercier E, Colnaghi R, Alcantara D, Chow E, Martell S, Tyson C, Hrynchak M, McGillivray B, Hamilton S, Marles S, Mhanni A, Dawson AJ, Pavlidis P, Qiao Y, Holden JJ, Lewis SM, O'Driscoll M, Rajcan-Separovic E (2011).
2212: 2497: 2205: 1711:"Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver" 2198: 359: 258: 2405: 2171: 1762:
Park SH, Paulsen SR, Gammon SR, et al. (2003). "Effects of thyroid state on AMP-activated protein kinase and acetyl-CoA carboxylase expression in muscle".
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Minokoshi Y, Alquier T, Furukawa N, et al. (2004). "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus".
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and the DNA repair system. With 1q21.1 deletion syndrome a disturbance occurs, which leads to increased DNA breaks. The role of CHD1L is similar to that of
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Stapleton D, Woollatt E, Mitchelhill KI, et al. (1997). "AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location".
2639: 2526: 845: 181: 2914: 826: 3887: 3352: 2243: 2225: 3989: 3870: 2002:"Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes" 1145:. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. 4443: 3576: 2445: 1296: 4414: 3640: 2615: 2151: 1278: 4433: 3896: 2430: 1045: 345: 3953: 3628: 1314:
Stapleton D, Mitchelhill KI, Gao G, Widmer J, Michell BJ, Teh T, House CM, Fernandez CS, Cox T, Witters LA, Kemp BE (February 1996).
4068: 2885: 2875: 2560: 1052: 322: 3567: 1358: 3836: 3508: 2870: 2861: 1265: 1244: 4224: 1261: 1526:"Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro" 244: 219: 52: 3251: 2748: 2739: 2396: 2342: 4339: 1633:"Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle" 1240: 2439: 1218:
PRKAB2 is involved in maintaining the energy level of cells. With 1q21.1-deletion syndrome this function was attenuated.
1122: 161: 1171: 1159: 358: 257: 2190: 3463: 3281: 2777: 351: 250: 4209: 4407: 4325: 4312: 4299: 4286: 4273: 4260: 4247: 3453: 3448: 3443: 3433: 3428: 3423: 3413: 3208: 2983: 2579: 2144: 4219: 4173: 4116: 3676: 3667: 3618: 2384: 2229: 1194: 1154: 890: 169: 1959:"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" 1846:"Variant screening of PRKAB2, a type 2 diabetes mellitus susceptibility candidate gene on 1q in Pima Indians" 4121: 3976: 3399: 871: 1130: 4142: 4061: 2675: 4214: 1668:"Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding" 1377:"Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding" 4400: 3242: 2137: 2056: 1921: 1804: 1722: 233: 148: 4178: 3750: 4438: 4111: 3853: 3807: 1945: 1619: 193: 1793:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 1028: 1007: 981: 960: 3113: 2822: 2117: 2074: 2031: 1988: 1937: 1900: 1865: 1832: 1779: 1750: 1697: 1654: 1611: 1582: 1547: 1512: 1466: 1414: 1396: 1337: 1134: 141: 45: 4384: 4157: 4152: 4126: 4054: 3706: 2948: 2938: 2933: 2851: 2842: 2772: 2763: 2709: 2700: 2357: 2107: 2099: 2064: 2021: 2013: 1978: 1970: 1929: 1890: 1857: 1822: 1812: 1771: 1740: 1730: 1687: 1679: 1644: 1603: 1572: 1537: 1502: 1456: 1446: 1404: 1388: 1327: 596: 438: 369: 313: 268: 189: 4204: 4188: 4101: 3532: 2603: 2598: 2593: 1213: 1126: 413: 2060: 1925: 1808: 1726: 28: 4353: 4242: 4183: 2112: 2087: 2026: 2001: 1692: 1667: 1491:"Non-catalytic beta- and gamma-subunit isoforms of the 5'-AMP-activated protein kinase" 1461: 1434: 1409: 1376: 1983: 1958: 1827: 1792: 1607: 760: 755: 750: 745: 740: 735: 730: 725: 720: 715: 710: 705: 689: 684: 679: 674: 669: 653: 648: 643: 638: 4427: 4147: 4106: 2656: 2588: 1745: 1710: 625: 1775: 1623: 173: 4380: 4096: 3527: 2352: 1949: 431: 210: 1359:"Entrez Gene: PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit" 197: 4320: 4255: 4091: 3733: 3365: 3305: 3188: 3108: 2832: 2088:"Large-scale mapping of human protein–protein interactions by mass spectrometry" 1683: 1392: 1301:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
1190: 1142: 4348: 514: 3821: 2295: 1138: 330: 227: 177: 1649: 1632: 1542: 1525: 1400: 4294: 4268: 2782: 1879:"Complete sequencing and characterization of 21,243 full-length human cDNAs" 1561:"Normalization and subtraction: two approaches to facilitate gene discovery" 1507: 1490: 1205: 790: 574: 452: 397: 384: 296: 283: 185: 2180:: Glycogen-Binding Domain Of The Amp-Activated Protein Kinase beta2 Subunit 2121: 2078: 2035: 1992: 1941: 1904: 1869: 1861: 1836: 1817: 1783: 1754: 1735: 1701: 1470: 1451: 1418: 1658: 1615: 1586: 1551: 1516: 1341: 1332: 1315: 1092: 1087: 3138: 3033: 3028: 3023: 1209: 1076: 935: 916: 2069: 2044: 1933: 3797: 3775: 3770: 3760: 3755: 3557: 3552: 3547: 3542: 3537: 3522: 3517: 3168: 3133: 2372: 2367: 2362: 2103: 2017: 1974: 1577: 1560: 1375:
Cheung, P C; Salt I P; Davies S P; Hardie D G; Carling D (March 2000).
902: 857: 118: 114: 110: 106: 102: 98: 94: 90: 86: 82: 78: 74: 4307: 4077: 4027: 4022: 4017: 4012: 4007: 4002: 3997: 3948: 3943: 3938: 3933: 3928: 3911: 3906: 3780: 3765: 3716: 3711: 3696: 3691: 3686: 3681: 3655: 3650: 3645: 3633: 3611: 3606: 3498: 3473: 3148: 2973: 2968: 2963: 2958: 2943: 2787: 2724: 2719: 2714: 2690: 2516: 2511: 2485: 2480: 2475: 2460: 2450: 2290: 2221: 1179: 1175: 1108: 1060: 812: 4368: 1845: 1137:(HMGCR), key enzymes involved in regulating de novo biosynthesis of 1895: 1878: 4281: 3923: 3916: 3826: 3723: 3623: 3601: 3596: 3591: 3586: 3581: 3493: 3488: 3483: 3478: 3468: 3438: 3418: 3295: 3290: 3271: 3266: 3256: 3232: 3227: 3222: 3198: 3193: 3183: 3178: 3173: 3163: 3143: 3128: 3123: 3118: 3098: 3093: 3083: 3078: 3073: 3068: 3063: 3053: 3048: 3043: 3038: 3018: 3013: 3008: 3003: 2998: 2993: 2978: 2928: 2923: 2817: 2812: 2807: 2802: 2797: 2792: 2753: 2685: 2680: 2629: 2624: 2550: 2545: 2540: 2506: 2498:
3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase
2300: 2285: 2280: 2275: 2270: 2265: 2045:"The DNA sequence and biological annotation of human chromosome 1" 1201: 1186: 775: 771: 4376: 3816: 3743: 3738: 3728: 3701: 3458: 3408: 3389: 3384: 3379: 3374: 3329: 3324: 3319: 3314: 3261: 3217: 3158: 3153: 3103: 3088: 3058: 2988: 2904: 2899: 2894: 2827: 2729: 2670: 2665: 2569: 2535: 2420: 2415: 2410: 2379: 2347: 2335: 2330: 2325: 2315: 2310: 1121:
The protein encoded by this gene is a regulatory subunit of the
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cells lead to the conclusion that anomalies appear with the
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Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
152:, protein kinase AMP-activated non-catalytic subunit beta 2 4046: 1844:
Prochazka M, Farook VS, Ossowski V, et al. (2003).
1435:"Understanding the impact of 1q21.1 copy number variant" 421: 4388: 1957:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
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regulation of signal transduction by p53 class mediator
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Gao G, Fernandez CS, Stapleton D, et al. (1996).
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Gregory SG, Barlow KF, McLay KE, et al. (2006).
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Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
586: 4233: 4197: 4166: 4135: 4084: 3988: 3886: 3869: 3852: 3835: 3806: 3666: 3566: 3507: 3398: 3364: 3304: 3280: 3241: 3207: 2913: 2884: 2860: 2841: 2762: 2738: 2699: 2655: 2638: 2614: 2578: 2559: 2525: 2496: 2429: 2395: 2255: 1666:Cheung PC, Salt IP, Davies SP, et al. (2000). 1021: 1000: 974: 953: 1877:Ota T, Suzuki Y, Nishikawa T, et al. (2004). 1524:Woods A, Cheung PC, Smith FC, et al. (1996). 1316:"Mammalian AMP-activated protein kinase subfamily" 1257: 1255: 1253: 1236: 1234: 1232: 1204:is an enzyme which is involved in untangling the 746:positive regulation of cold-induced thermogenesis 368: 267: 2086:Ewing RM, Chu P, Elisma F, et al. (2007). 16:Protein-coding gene in the species Homo sapiens 1370: 1368: 1262:GRCm38: Ensembl release 89: ENSMUSG00000038205 1135:beta-hydroxy beta-methylglutaryl-CoA reductase 1105:5'-AMP-activated protein kinase subunit beta-2 4408: 4062: 2257:Non-specific serine/threonine protein kinases 2206: 2145: 711:regulation of fatty acid biosynthetic process 8: 1709:Xu XR, Huang J, Xu ZG, et al. (2002). 1241:GRCh38: Ensembl release 89: ENSG00000131791 680:nucleotide-activated protein kinase complex 4415: 4401: 4069: 4055: 4047: 3985: 3971: 3361: 3347: 2640:Goodpasture-antigen-binding protein kinase 2252: 2238: 2213: 2199: 2191: 2152: 2138: 2130: 1631:Thornton C, Snowden MA, Carling D (1998). 786: 621: 471:Skeletal muscle tissue of rectus abdominis 409: 308: 205: 63: 3353:Serine/threonine-specific protein kinases 2527:(isocitrate dehydrogenase (NADP+)) kinase 2244:Serine/threonine-specific protein kinases 2226:Serine/threonine-specific protein kinases 2111: 2068: 2025: 1982: 1894: 1826: 1816: 1744: 1734: 1691: 1648: 1576: 1541: 1506: 1460: 1450: 1408: 1331: 3888:Receptor protein serine/threonine kinase 1559:Bonaldo MF, Lennon G, Soares MB (1997). 1353: 1351: 475:Skeletal muscle tissue of biceps brachii 4344: 3871:Low-density-lipoprotein receptor kinase 2167: 1228: 18: 2616:Fas-activated serine/threonine kinase 639:AMP-activated protein kinase activity 373: 334: 329: 272: 231: 226: 7: 4365: 4363: 3897:Bone morphogenetic protein receptors 2431:Dephospho-(reductase kinase) kinase 533:medial head of gastrocnemius muscle 4387:. You can help Knowledge (XXG) by 2886:G-protein coupled receptor kinases 1018: 997: 971: 950: 926: 907: 881: 862: 836: 817: 591: 509: 447: 426: 14: 2876:Beta adrenergic receptor kinase-2 2561:(tyrosine 3-monooxygenase) kinase 1111:that in humans is encoded by the 4367: 4347: 3568:Mitogen-activated protein kinase 2170: 741:regulation of catalytic activity 595: 357: 350: 344: 321: 256: 249: 243: 218: 27: 3954:Anti-MĂĽllerian hormone receptor 3837:(acetyl-CoA carboxylase) kinase 3509:(RNA-polymerase)-subunit kinase 2871:Beta adrenergic receptor kinase 2862:Beta adrenergic receptor kinase 1776:10.1152/japplphysiol.00504.2002 721:fatty acid biosynthetic process 3577:Extracellular signal-regulated 606:More reference expression data 575:More reference expression data 1: 4444:Human chromosome 1 gene stubs 3641:P38 mitogen-activated protein 2740:cGMP-dependent protein kinase 2701:cAMP-dependent protein kinase 2397:Pyruvate dehydrogenase kinase 2343:Ataxia telangiectasia mutated 1608:10.1016/S0014-5793(97)00569-3 342: 241: 2440:AMP-activated protein kinase 1797:Proc. Natl. Acad. Sci. U.S.A 1715:Proc. Natl. Acad. Sci. U.S.A 1123:AMP-activated protein kinase 756:regulation of macroautophagy 716:fatty acid metabolic process 4434:Genes on human chromosome 1 3355:(EC 2.7.11.21-EC 2.7.11.30) 1160:1q21.1 duplication syndrome 4460: 4362: 3282:Elongation factor 2 kinase 2246:(EC 2.7.11.1-EC 2.7.11.20) 4225:Michaelis–Menten kinetics 3984: 3970: 3677:MAP kinase kinase kinases 3360: 3346: 3209:Myosin light-chain kinase 2915:Ca2+/calmodulin-dependent 2580:Myosin-heavy-chain kinase 2251: 2237: 2165: 1684:10.1042/0264-6021:3460659 1393:10.1042/0264-6021:3460659 1297:"Mouse PubMed Reference:" 1279:"Human PubMed Reference:" 1170:PRKAB2 has been shown to 1091: 1086: 1082: 1075: 1059: 1046:Chr 1: 147.16 – 147.17 Mb 1040: 1025: 1004: 993: 978: 957: 946: 933: 929: 914: 910: 901: 888: 884: 869: 865: 856: 843: 839: 824: 820: 811: 796: 789: 785: 769: 649:identical protein binding 624: 620: 603: 594: 585: 572: 537:quadriceps femoris muscle 521: 512: 459: 450: 420: 412: 408: 391: 378: 341: 320: 311: 307: 290: 277: 240: 217: 208: 204: 159: 156: 146: 139: 134: 71: 66: 49: 44: 39: 35: 26: 21: 4117:Diffusion-limited enzyme 3977:Dual-specificity kinases 1650:10.1074/jbc.273.20.12443 1543:10.1074/jbc.271.48.30517 1195:1q21.1 deletion syndrome 1155:1q21.1 deletion syndrome 557:tibialis anterior muscle 3400:Cyclin-dependent kinase 1508:10.1074/jbc.271.15.8675 1053:Chr 3: 97.57 – 97.58 Mb 731:protein phosphorylation 561:vastus lateralis muscle 1862:10.1006/mcpr.2002.0439 1818:10.1073/pnas.242603899 1736:10.1073/pnas.241522398 1452:10.1186/1750-1172-6-54 1387:(3). ENGLAND: 659–69. 1185:Research on the genes 1131:acetyl-CoA carboxylase 654:protein kinase binding 549:triceps brachii muscle 4210:Eadie–Hofstee diagram 4143:Allosteric regulation 1333:10.1074/jbc.271.2.611 1149:Related gene problems 4220:Lineweaver–Burk plot 3243:Phosphorylase kinase 541:facial motor nucleus 479:gastrocnemius muscle 336:Chromosome 3 (mouse) 234:Chromosome 1 (human) 67:List of PDB id codes 40:Available structures 2070:10.1038/nature04727 2061:2006Natur.441..315G 1934:10.1038/nature02440 1926:2004Natur.428..569M 1809:2002PNAS...9916899M 1727:2001PNAS...9815089X 1439:Orphanet J Rare Dis 736:signal transduction 4375:This article on a 4179:Enzyme superfamily 4112:Enzyme promiscuity 3854:Tropomyosin kinase 3808:Tau-protein kinase 2104:10.1038/msb4100134 2018:10.1101/gr.4039406 1975:10.1101/gr.2596504 1578:10.1101/gr.6.9.791 1189:and PRKAB2 within 891:ENSMUSG00000038205 699:Biological process 663:Cellular component 632:Molecular function 525:epithelium of lens 495:buccal mucosa cell 198:PRKAB2 - orthologs 4396: 4395: 4335: 4334: 4044: 4043: 4040: 4039: 4036: 4035: 3966: 3965: 3962: 3961: 3342: 3341: 3338: 3337: 2823:Protein kinase N1 2778:Protein kinase Cζ 2188: 2187: 1850:Mol. Cell. Probes 1803:(26): 16899–903. 1102: 1101: 1098: 1097: 1071: 1070: 1036: 1035: 1015: 1014: 989: 988: 968: 967: 942: 941: 923: 922: 897: 896: 878: 877: 852: 851: 833: 832: 781: 780: 751:carnitine shuttle 616: 615: 612: 611: 581: 580: 568: 567: 506: 505: 404: 403: 303: 302: 130: 129: 126: 125: 50:Ortholog search: 4451: 4417: 4410: 4403: 4371: 4364: 4352: 4351: 4343: 4215:Hanes–Woolf plot 4158:Enzyme activator 4153:Enzyme inhibitor 4127:Enzyme catalysis 4071: 4064: 4057: 4048: 3986: 3972: 3619:C-Jun N-terminal 3362: 3348: 2852:Rhodopsin kinase 2843:Rhodopsin kinase 2773:Protein kinase C 2764:Protein kinase C 2749:Protein kinase G 2710:Protein kinase A 2321:Protein kinase B 2253: 2239: 2215: 2208: 2201: 2192: 2174: 2154: 2147: 2140: 2131: 2125: 2115: 2082: 2072: 2055:(7091): 315–21. 2039: 2029: 1996: 1986: 1953: 1920:(6982): 569–74. 1908: 1898: 1873: 1840: 1830: 1820: 1787: 1764:J. Appl. Physiol 1758: 1748: 1738: 1721:(26): 15089–94. 1705: 1695: 1662: 1652: 1643:(20): 12443–50. 1627: 1590: 1580: 1555: 1545: 1536:(17): 10282–90. 1520: 1510: 1475: 1474: 1464: 1454: 1429: 1423: 1422: 1412: 1372: 1363: 1362: 1355: 1346: 1345: 1335: 1311: 1305: 1304: 1293: 1287: 1286: 1275: 1269: 1259: 1248: 1238: 1129:and inactivates 1084: 1083: 1055: 1048: 1031: 1019: 1010: 998: 994:RefSeq (protein) 984: 972: 963: 951: 927: 908: 882: 863: 837: 818: 787: 706:lipid metabolism 622: 608: 599: 592: 577: 517: 515:Top expressed in 510: 455: 453:Top expressed in 448: 427: 410: 400: 387: 376: 361: 354: 348: 337: 325: 309: 299: 286: 275: 260: 253: 247: 236: 222: 206: 200: 151: 144: 121: 64: 58: 37: 36: 31: 19: 4459: 4458: 4454: 4453: 4452: 4450: 4449: 4448: 4424: 4423: 4422: 4421: 4360: 4358: 4346: 4338: 4336: 4331: 4243:Oxidoreductases 4229: 4205:Enzyme kinetics 4193: 4189:List of enzymes 4162: 4131: 4102:Catalytic triad 4080: 4075: 4045: 4032: 3980: 3958: 3882: 3865: 3848: 3831: 3802: 3662: 3562: 3533:P70-S6 Kinase 1 3503: 3394: 3356: 3334: 3300: 3276: 3237: 3203: 2909: 2880: 2856: 2837: 2758: 2734: 2695: 2651: 2634: 2610: 2604:Aurora C kinase 2599:Aurora B kinase 2594:Aurora A kinase 2574: 2555: 2521: 2492: 2425: 2391: 2247: 2233: 2219: 2189: 2184: 2181: 2175: 2161: 2158: 2128: 2092:Mol. Syst. Biol 2085: 2042: 1999: 1969:(10B): 2121–7. 1956: 1911: 1876: 1843: 1790: 1761: 1708: 1665: 1630: 1593: 1558: 1523: 1501:(15): 8675–81. 1488: 1484: 1482:Further reading 1479: 1478: 1431: 1430: 1426: 1374: 1373: 1366: 1357: 1356: 1349: 1313: 1312: 1308: 1295: 1294: 1290: 1277: 1276: 1272: 1260: 1251: 1239: 1230: 1225: 1214:Werner syndrome 1168: 1151: 1093:View/Edit Mouse 1088:View/Edit Human 1051: 1044: 1041:Location (UCSC) 1027: 1006: 980: 959: 872:ENSG00000131791 765: 694: 658: 644:protein binding 604: 573: 564: 559: 555: 553:ascending aorta 551: 547: 545:muscle of thigh 543: 539: 535: 531: 527: 513: 502: 499:tibial arteries 497: 493: 491:muscle of thigh 489: 485: 481: 477: 473: 469: 465: 451: 395: 382: 374: 364: 363: 362: 355: 335: 312:Gene location ( 294: 281: 273: 263: 262: 261: 254: 232: 209:Gene location ( 160: 147: 140: 73: 51: 17: 12: 11: 5: 4457: 4455: 4447: 4446: 4441: 4436: 4426: 4425: 4420: 4419: 4412: 4405: 4397: 4394: 4393: 4372: 4357: 4356: 4333: 4332: 4330: 4329: 4316: 4303: 4290: 4277: 4264: 4251: 4237: 4235: 4231: 4230: 4228: 4227: 4222: 4217: 4212: 4207: 4201: 4199: 4195: 4194: 4192: 4191: 4186: 4181: 4176: 4170: 4168: 4167:Classification 4164: 4163: 4161: 4160: 4155: 4150: 4145: 4139: 4137: 4133: 4132: 4130: 4129: 4124: 4119: 4114: 4109: 4104: 4099: 4094: 4088: 4086: 4082: 4081: 4076: 4074: 4073: 4066: 4059: 4051: 4042: 4041: 4038: 4037: 4034: 4033: 4031: 4030: 4025: 4020: 4015: 4010: 4005: 4000: 3994: 3992: 3982: 3981: 3975: 3968: 3967: 3964: 3963: 3960: 3959: 3957: 3956: 3951: 3946: 3941: 3936: 3931: 3926: 3921: 3920: 3919: 3914: 3909: 3904: 3893: 3891: 3890:(EC 2.7.11.30) 3884: 3883: 3881: 3880: 3876: 3874: 3873:(EC 2.7.11.29) 3867: 3866: 3864: 3863: 3859: 3857: 3856:(EC 2.7.11.28) 3850: 3849: 3847: 3846: 3842: 3840: 3839:(EC 2.7.11.27) 3833: 3832: 3830: 3829: 3824: 3819: 3813: 3811: 3810:(EC 2.7.11.26) 3804: 3803: 3801: 3800: 3795: 3790: 3789: 3788: 3783: 3778: 3773: 3768: 3763: 3758: 3748: 3747: 3746: 3741: 3736: 3731: 3721: 3720: 3719: 3714: 3709: 3704: 3699: 3694: 3689: 3684: 3673: 3671: 3670:(EC 2.7.11.25) 3664: 3663: 3661: 3660: 3659: 3658: 3653: 3648: 3638: 3637: 3636: 3631: 3626: 3616: 3615: 3614: 3609: 3604: 3599: 3594: 3589: 3584: 3573: 3571: 3570:(EC 2.7.11.24) 3564: 3563: 3561: 3560: 3555: 3550: 3545: 3540: 3535: 3530: 3525: 3520: 3514: 3512: 3511:(EC 2.7.11.23) 3505: 3504: 3502: 3501: 3496: 3491: 3486: 3481: 3476: 3471: 3466: 3461: 3456: 3451: 3446: 3441: 3436: 3431: 3426: 3421: 3416: 3411: 3405: 3403: 3402:(EC 2.7.11.22) 3396: 3395: 3393: 3392: 3387: 3382: 3377: 3371: 3369: 3368:(EC 2.7.11.21) 3358: 3357: 3351: 3344: 3343: 3340: 3339: 3336: 3335: 3333: 3332: 3327: 3322: 3317: 3311: 3309: 3308:(EC 2.7.11.21) 3302: 3301: 3299: 3298: 3293: 3287: 3285: 3284:(EC 2.7.11.20) 3278: 3277: 3275: 3274: 3269: 3264: 3259: 3254: 3248: 3246: 3245:(EC 2.7.11.19) 3239: 3238: 3236: 3235: 3230: 3225: 3220: 3214: 3212: 3211:(EC 2.7.11.18) 3205: 3204: 3202: 3201: 3196: 3191: 3186: 3181: 3176: 3171: 3166: 3161: 3156: 3151: 3146: 3141: 3136: 3131: 3126: 3121: 3116: 3111: 3106: 3101: 3096: 3091: 3086: 3081: 3076: 3071: 3066: 3061: 3056: 3051: 3046: 3041: 3036: 3031: 3026: 3021: 3016: 3011: 3006: 3001: 2996: 2991: 2986: 2981: 2976: 2971: 2966: 2961: 2956: 2951: 2946: 2941: 2936: 2931: 2926: 2920: 2918: 2917:(EC 2.7.11.17) 2911: 2910: 2908: 2907: 2902: 2897: 2891: 2889: 2888:(EC 2.7.11.16) 2882: 2881: 2879: 2878: 2873: 2867: 2865: 2864:(EC 2.7.11.15) 2858: 2857: 2855: 2854: 2848: 2846: 2845:(EC 2.7.11.14) 2839: 2838: 2836: 2835: 2830: 2825: 2820: 2815: 2810: 2805: 2800: 2795: 2790: 2785: 2780: 2775: 2769: 2767: 2766:(EC 2.7.11.13) 2760: 2759: 2757: 2756: 2751: 2745: 2743: 2742:(EC 2.7.11.12) 2736: 2735: 2733: 2732: 2727: 2722: 2717: 2712: 2706: 2704: 2703:(EC 2.7.11.11) 2697: 2696: 2694: 2693: 2688: 2683: 2678: 2673: 2668: 2662: 2660: 2659:(EC 2.7.11.10) 2653: 2652: 2650: 2649: 2645: 2643: 2636: 2635: 2633: 2632: 2627: 2621: 2619: 2612: 2611: 2609: 2608: 2607: 2606: 2601: 2596: 2585: 2583: 2576: 2575: 2573: 2572: 2566: 2564: 2557: 2556: 2554: 2553: 2548: 2543: 2538: 2532: 2530: 2523: 2522: 2520: 2519: 2514: 2509: 2503: 2501: 2494: 2493: 2491: 2490: 2489: 2488: 2483: 2478: 2470: 2469: 2468: 2463: 2455: 2454: 2453: 2448: 2436: 2434: 2427: 2426: 2424: 2423: 2418: 2413: 2408: 2402: 2400: 2393: 2392: 2390: 2389: 2388: 2387: 2377: 2376: 2375: 2370: 2365: 2360: 2350: 2345: 2340: 2339: 2338: 2333: 2328: 2318: 2313: 2308: 2303: 2298: 2293: 2288: 2283: 2278: 2273: 2268: 2262: 2260: 2249: 2248: 2242: 2235: 2234: 2220: 2218: 2217: 2210: 2203: 2195: 2186: 2185: 2183: 2182: 2176: 2169: 2166: 2163: 2162: 2159: 2157: 2156: 2149: 2142: 2134: 2127: 2126: 2083: 2040: 1997: 1954: 1909: 1896:10.1038/ng1285 1874: 1841: 1788: 1759: 1706: 1663: 1628: 1591: 1571:(9): 791–806. 1556: 1521: 1485: 1483: 1480: 1477: 1476: 1424: 1364: 1347: 1306: 1288: 1270: 1249: 1227: 1226: 1224: 1221: 1220: 1219: 1216: 1167: 1164: 1163: 1162: 1157: 1150: 1147: 1127:phosphorylates 1100: 1099: 1096: 1095: 1090: 1080: 1079: 1073: 1072: 1069: 1068: 1066: 1064: 1057: 1056: 1049: 1042: 1038: 1037: 1034: 1033: 1023: 1022: 1016: 1013: 1012: 1002: 1001: 995: 991: 990: 987: 986: 976: 975: 969: 966: 965: 955: 954: 948: 944: 943: 940: 939: 931: 930: 924: 921: 920: 912: 911: 905: 899: 898: 895: 894: 886: 885: 879: 876: 875: 867: 866: 860: 854: 853: 850: 849: 841: 840: 834: 831: 830: 822: 821: 815: 809: 808: 803: 798: 794: 793: 783: 782: 779: 778: 767: 766: 764: 763: 758: 753: 748: 743: 738: 733: 728: 726:macroautophagy 723: 718: 713: 708: 702: 700: 696: 695: 693: 692: 687: 682: 677: 672: 666: 664: 660: 659: 657: 656: 651: 646: 641: 635: 633: 629: 628: 618: 617: 614: 613: 610: 609: 601: 600: 589: 583: 582: 579: 578: 570: 569: 566: 565: 563: 562: 558: 554: 550: 546: 542: 538: 534: 530: 526: 522: 519: 518: 507: 504: 503: 501: 500: 496: 492: 488: 487:saphenous vein 484: 483:body of tongue 480: 476: 472: 468: 467:biceps brachii 464: 463:jejunal mucosa 460: 457: 456: 444: 443: 435: 424: 418: 417: 414:RNA expression 406: 405: 402: 401: 393: 389: 388: 380: 377: 372: 366: 365: 356: 349: 343: 339: 338: 333: 327: 326: 318: 317: 305: 304: 301: 300: 292: 288: 287: 279: 276: 271: 265: 264: 255: 248: 242: 238: 237: 230: 224: 223: 215: 214: 202: 201: 158: 154: 153: 145: 137: 136: 132: 131: 128: 127: 124: 123: 69: 68: 60: 59: 48: 42: 41: 33: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 4456: 4445: 4442: 4440: 4437: 4435: 4432: 4431: 4429: 4418: 4413: 4411: 4406: 4404: 4399: 4398: 4392: 4390: 4386: 4382: 4378: 4373: 4370: 4366: 4361: 4355: 4350: 4345: 4341: 4327: 4323: 4322: 4317: 4314: 4310: 4309: 4304: 4301: 4297: 4296: 4291: 4288: 4284: 4283: 4278: 4275: 4271: 4270: 4265: 4262: 4258: 4257: 4252: 4249: 4245: 4244: 4239: 4238: 4236: 4232: 4226: 4223: 4221: 4218: 4216: 4213: 4211: 4208: 4206: 4203: 4202: 4200: 4196: 4190: 4187: 4185: 4184:Enzyme family 4182: 4180: 4177: 4175: 4172: 4171: 4169: 4165: 4159: 4156: 4154: 4151: 4149: 4148:Cooperativity 4146: 4144: 4141: 4140: 4138: 4134: 4128: 4125: 4123: 4120: 4118: 4115: 4113: 4110: 4108: 4107:Oxyanion hole 4105: 4103: 4100: 4098: 4095: 4093: 4090: 4089: 4087: 4083: 4079: 4072: 4067: 4065: 4060: 4058: 4053: 4052: 4049: 4029: 4026: 4024: 4021: 4019: 4016: 4014: 4011: 4009: 4006: 4004: 4001: 3999: 3996: 3995: 3993: 3991: 3987: 3983: 3978: 3973: 3969: 3955: 3952: 3950: 3947: 3945: 3942: 3940: 3937: 3935: 3932: 3930: 3927: 3925: 3922: 3918: 3915: 3913: 3910: 3908: 3905: 3903: 3900: 3899: 3898: 3895: 3894: 3892: 3889: 3885: 3878: 3877: 3875: 3872: 3868: 3861: 3860: 3858: 3855: 3851: 3844: 3843: 3841: 3838: 3834: 3828: 3825: 3823: 3820: 3818: 3815: 3814: 3812: 3809: 3805: 3799: 3796: 3794: 3791: 3787: 3784: 3782: 3779: 3777: 3774: 3772: 3769: 3767: 3764: 3762: 3759: 3757: 3754: 3753: 3752: 3749: 3745: 3742: 3740: 3737: 3735: 3732: 3730: 3727: 3726: 3725: 3722: 3718: 3715: 3713: 3710: 3708: 3705: 3703: 3700: 3698: 3695: 3693: 3690: 3688: 3685: 3683: 3680: 3679: 3678: 3675: 3674: 3672: 3669: 3665: 3657: 3654: 3652: 3649: 3647: 3644: 3643: 3642: 3639: 3635: 3632: 3630: 3627: 3625: 3622: 3621: 3620: 3617: 3613: 3610: 3608: 3605: 3603: 3600: 3598: 3595: 3593: 3590: 3588: 3585: 3583: 3580: 3579: 3578: 3575: 3574: 3572: 3569: 3565: 3559: 3556: 3554: 3551: 3549: 3546: 3544: 3541: 3539: 3536: 3534: 3531: 3529: 3526: 3524: 3521: 3519: 3516: 3515: 3513: 3510: 3506: 3500: 3497: 3495: 3492: 3490: 3487: 3485: 3482: 3480: 3477: 3475: 3472: 3470: 3467: 3465: 3462: 3460: 3457: 3455: 3452: 3450: 3447: 3445: 3442: 3440: 3437: 3435: 3432: 3430: 3427: 3425: 3422: 3420: 3417: 3415: 3412: 3410: 3407: 3406: 3404: 3401: 3397: 3391: 3388: 3386: 3383: 3381: 3378: 3376: 3373: 3372: 3370: 3367: 3363: 3359: 3354: 3349: 3345: 3331: 3328: 3326: 3323: 3321: 3318: 3316: 3313: 3312: 3310: 3307: 3303: 3297: 3294: 3292: 3289: 3288: 3286: 3283: 3279: 3273: 3270: 3268: 3265: 3263: 3260: 3258: 3255: 3253: 3250: 3249: 3247: 3244: 3240: 3234: 3231: 3229: 3226: 3224: 3221: 3219: 3216: 3215: 3213: 3210: 3206: 3200: 3197: 3195: 3192: 3190: 3187: 3185: 3182: 3180: 3177: 3175: 3172: 3170: 3167: 3165: 3162: 3160: 3157: 3155: 3152: 3150: 3147: 3145: 3142: 3140: 3137: 3135: 3132: 3130: 3127: 3125: 3122: 3120: 3117: 3115: 3112: 3110: 3107: 3105: 3102: 3100: 3097: 3095: 3092: 3090: 3087: 3085: 3082: 3080: 3077: 3075: 3072: 3070: 3067: 3065: 3062: 3060: 3057: 3055: 3052: 3050: 3047: 3045: 3042: 3040: 3037: 3035: 3032: 3030: 3027: 3025: 3022: 3020: 3017: 3015: 3012: 3010: 3007: 3005: 3002: 3000: 2997: 2995: 2992: 2990: 2987: 2985: 2982: 2980: 2977: 2975: 2972: 2970: 2967: 2965: 2962: 2960: 2957: 2955: 2952: 2950: 2947: 2945: 2942: 2940: 2937: 2935: 2932: 2930: 2927: 2925: 2922: 2921: 2919: 2916: 2912: 2906: 2903: 2901: 2898: 2896: 2893: 2892: 2890: 2887: 2883: 2877: 2874: 2872: 2869: 2868: 2866: 2863: 2859: 2853: 2850: 2849: 2847: 2844: 2840: 2834: 2831: 2829: 2826: 2824: 2821: 2819: 2816: 2814: 2811: 2809: 2806: 2804: 2801: 2799: 2796: 2794: 2791: 2789: 2786: 2784: 2781: 2779: 2776: 2774: 2771: 2770: 2768: 2765: 2761: 2755: 2752: 2750: 2747: 2746: 2744: 2741: 2737: 2731: 2728: 2726: 2723: 2721: 2718: 2716: 2713: 2711: 2708: 2707: 2705: 2702: 2698: 2692: 2689: 2687: 2684: 2682: 2679: 2677: 2674: 2672: 2669: 2667: 2664: 2663: 2661: 2658: 2654: 2647: 2646: 2644: 2642:(EC 2.7.11.9) 2641: 2637: 2631: 2628: 2626: 2623: 2622: 2620: 2618:(EC 2.7.11.8) 2617: 2613: 2605: 2602: 2600: 2597: 2595: 2592: 2591: 2590: 2589:Aurora kinase 2587: 2586: 2584: 2582:(EC 2.7.11.7) 2581: 2577: 2571: 2568: 2567: 2565: 2563:(EC 2.7.11.6) 2562: 2558: 2552: 2549: 2547: 2544: 2542: 2539: 2537: 2534: 2533: 2531: 2529:(EC 2.7.11.5) 2528: 2524: 2518: 2515: 2513: 2510: 2508: 2505: 2504: 2502: 2500:(EC 2.7.11.4) 2499: 2495: 2487: 2484: 2482: 2479: 2477: 2474: 2473: 2471: 2467: 2464: 2462: 2459: 2458: 2456: 2452: 2449: 2447: 2444: 2443: 2441: 2438: 2437: 2435: 2433:(EC 2.7.11.3) 2432: 2428: 2422: 2419: 2417: 2414: 2412: 2409: 2407: 2404: 2403: 2401: 2399:(EC 2.7.11.2) 2398: 2394: 2386: 2383: 2382: 2381: 2378: 2374: 2371: 2369: 2366: 2364: 2361: 2359: 2356: 2355: 2354: 2353:EIF-2 kinases 2351: 2349: 2346: 2344: 2341: 2337: 2334: 2332: 2329: 2327: 2324: 2323: 2322: 2319: 2317: 2314: 2312: 2309: 2307: 2304: 2302: 2299: 2297: 2294: 2292: 2289: 2287: 2284: 2282: 2279: 2277: 2274: 2272: 2269: 2267: 2264: 2263: 2261: 2259:(EC 2.7.11.1) 2258: 2254: 2250: 2245: 2240: 2236: 2231: 2227: 2223: 2216: 2211: 2209: 2204: 2202: 2197: 2196: 2193: 2179: 2173: 2168: 2164: 2155: 2150: 2148: 2143: 2141: 2136: 2135: 2132: 2123: 2119: 2114: 2109: 2105: 2101: 2097: 2093: 2089: 2084: 2080: 2076: 2071: 2066: 2062: 2058: 2054: 2050: 2046: 2041: 2037: 2033: 2028: 2023: 2019: 2015: 2011: 2007: 2003: 1998: 1994: 1990: 1985: 1980: 1976: 1972: 1968: 1964: 1960: 1955: 1951: 1947: 1943: 1939: 1935: 1931: 1927: 1923: 1919: 1915: 1910: 1906: 1902: 1897: 1892: 1888: 1884: 1880: 1875: 1871: 1867: 1863: 1859: 1855: 1851: 1847: 1842: 1838: 1834: 1829: 1824: 1819: 1814: 1810: 1806: 1802: 1798: 1794: 1789: 1785: 1781: 1777: 1773: 1770:(6): 2081–8. 1769: 1765: 1760: 1756: 1752: 1747: 1742: 1737: 1732: 1728: 1724: 1720: 1716: 1712: 1707: 1703: 1699: 1694: 1689: 1685: 1681: 1678:(3): 659–69. 1677: 1673: 1669: 1664: 1660: 1656: 1651: 1646: 1642: 1638: 1637:J. Biol. Chem 1634: 1629: 1625: 1621: 1617: 1613: 1609: 1605: 1601: 1597: 1592: 1588: 1584: 1579: 1574: 1570: 1566: 1562: 1557: 1553: 1549: 1544: 1539: 1535: 1531: 1530:J. Biol. Chem 1527: 1522: 1518: 1514: 1509: 1504: 1500: 1496: 1495:J. Biol. Chem 1492: 1487: 1486: 1481: 1472: 1468: 1463: 1458: 1453: 1448: 1444: 1440: 1436: 1428: 1425: 1420: 1416: 1411: 1406: 1402: 1398: 1394: 1390: 1386: 1382: 1378: 1371: 1369: 1365: 1360: 1354: 1352: 1348: 1343: 1339: 1334: 1329: 1325: 1321: 1317: 1310: 1307: 1302: 1298: 1292: 1289: 1284: 1280: 1274: 1271: 1267: 1263: 1258: 1256: 1254: 1250: 1246: 1242: 1237: 1235: 1233: 1229: 1222: 1217: 1215: 1211: 1207: 1203: 1200: 1199: 1198: 1196: 1192: 1188: 1183: 1181: 1177: 1173: 1165: 1161: 1158: 1156: 1153: 1152: 1148: 1146: 1144: 1140: 1136: 1132: 1128: 1124: 1119: 1117: 1114: 1110: 1106: 1094: 1089: 1085: 1081: 1078: 1074: 1067: 1065: 1062: 1058: 1054: 1050: 1047: 1043: 1039: 1032: 1030: 1024: 1020: 1017: 1011: 1009: 1003: 999: 996: 992: 985: 983: 977: 973: 970: 964: 962: 956: 952: 949: 947:RefSeq (mRNA) 945: 938: 937: 932: 928: 925: 919: 918: 913: 909: 906: 904: 900: 893: 892: 887: 883: 880: 874: 873: 868: 864: 861: 859: 855: 848: 847: 842: 838: 835: 829: 828: 823: 819: 816: 814: 810: 807: 804: 802: 799: 795: 792: 788: 784: 777: 773: 768: 762: 759: 757: 754: 752: 749: 747: 744: 742: 739: 737: 734: 732: 729: 727: 724: 722: 719: 717: 714: 712: 709: 707: 704: 703: 701: 698: 697: 691: 688: 686: 683: 681: 678: 676: 673: 671: 668: 667: 665: 662: 661: 655: 652: 650: 647: 645: 642: 640: 637: 636: 634: 631: 630: 627: 626:Gene ontology 623: 619: 607: 602: 598: 593: 590: 588: 584: 576: 571: 560: 556: 552: 548: 544: 540: 536: 532: 528: 524: 523: 520: 516: 511: 508: 498: 494: 490: 486: 482: 478: 474: 470: 466: 462: 461: 458: 454: 449: 446: 445: 442: 440: 436: 434: 433: 429: 428: 425: 423: 419: 415: 411: 407: 399: 394: 390: 386: 381: 375:3|3 F2.2 371: 367: 360: 353: 347: 340: 332: 328: 324: 319: 315: 310: 306: 298: 293: 289: 285: 280: 270: 266: 259: 252: 246: 239: 235: 229: 225: 221: 216: 212: 207: 203: 199: 195: 191: 187: 183: 179: 175: 171: 167: 163: 155: 150: 143: 138: 133: 122: 120: 116: 112: 108: 104: 100: 96: 92: 88: 84: 80: 76: 70: 65: 62: 61: 57: 54: 47: 43: 38: 34: 30: 25: 20: 4389:expanding it 4381:chromosome 1 4374: 4359: 4321:Translocases 4318: 4305: 4292: 4279: 4266: 4256:Transferases 4253: 4240: 4097:Binding site 3528:P70S6 kinase 2465: 2177: 2095: 2091: 2052: 2048: 2012:(1): 55–65. 2009: 2005: 1966: 1962: 1917: 1913: 1886: 1882: 1856:(6): 421–7. 1853: 1849: 1800: 1796: 1767: 1763: 1718: 1714: 1675: 1671: 1640: 1636: 1602:(3): 452–6. 1599: 1595: 1568: 1564: 1533: 1529: 1498: 1494: 1442: 1438: 1427: 1384: 1380: 1326:(2): 611–4. 1323: 1319: 1309: 1300: 1291: 1282: 1273: 1184: 1169: 1166:Interactions 1120: 1112: 1104: 1103: 1026: 1005: 979: 958: 934: 915: 889: 870: 844: 825: 805: 800: 437: 430: 295:147,172,550 282:147,155,106 157:External IDs 72: 4092:Active site 3979:(EC 2.7.12) 3366:Polo kinase 3306:Polo kinase 2160:PDB gallery 1889:(1): 40–5. 1320:J Biol Chem 1191:lymphoblast 1143:cholesterol 675:nucleoplasm 396:97,581,128 383:97,565,509 135:Identifiers 4428:Categories 4295:Isomerases 4269:Hydrolases 4136:Regulation 2657:IÎşB kinase 2232:2.7.11-12) 2006:Genome Res 1963:Genome Res 1883:Nat. Genet 1672:Biochem. J 1565:Genome Res 1381:Biochem. J 1268:, May 2017 1247:, May 2017 1223:References 1206:chromatids 1139:fatty acid 1133:(ACC) and 529:knee joint 441:(ortholog) 178:HomoloGene 4439:EC 2.7.11 4379:on human 4174:EC number 2783:PKC alpha 2098:(1): 89. 1596:FEBS Lett 1401:0264-6021 1212:with the 1029:NP_892042 1008:NP_005390 982:NM_182997 961:NM_005399 791:Orthologs 690:cytoplasm 186:GeneCards 4198:Kinetics 4122:Cofactor 4085:Activity 3139:KIAA0999 3034:MAPKAPK5 3029:MAPKAPK3 3024:MAPKAPK2 2122:17353931 2079:16710414 2036:16344560 1993:15489334 1942:15058305 1905:14702039 1870:12490143 1837:12477932 1784:12433937 1755:11752456 1702:10698692 1624:39329574 1471:21824431 1419:10698692 1264:– 1243:– 1210:helicase 1172:interact 1077:Wikidata 770:Sources: 4354:Biology 4308:Ligases 4078:Enzymes 3798:MAP3K14 3776:MAP3K11 3771:MAP3K10 3761:MAP3K13 3756:MAP3K12 3558:RPS6KC1 3553:RPS6KA1 3548:RPS6KA3 3543:RPS6KA2 3538:RPS6KB2 3523:RPS6KA4 3518:RPS6KA5 3169:Kalirin 3134:SNF1LK2 2373:EIF2AK4 2368:EIF2AK3 2222:Kinases 2113:1847948 2057:Bibcode 2027:1356129 1950:4302317 1922:Bibcode 1805:Bibcode 1723:Bibcode 1693:1220898 1659:9575201 1616:9224708 1587:8889548 1552:8626596 1517:8621499 1462:3180300 1410:1220898 1342:8557660 1266:Ensembl 1245:Ensembl 903:UniProt 858:Ensembl 797:Species 776:QuickGO 685:nucleus 670:cytosol 416:pattern 174:1336185 142:Aliases 4340:Portal 4282:Lyases 4028:MAP2K7 4023:MAP2K6 4018:MAP2K5 4013:MAP2K4 4008:MAP2K3 4003:MAP2K2 3998:MAP2K1 3949:ACVRL1 3944:ACVR2B 3939:ACVR2A 3934:ACVR1C 3929:ACVR1B 3912:BMPR1B 3907:BMPR1A 3781:MAP3K7 3766:MAP3K9 3717:MAP3K8 3712:MAP3K7 3707:MAP3K6 3702:MAP3K5 3697:MAP3K4 3692:MAP3K3 3687:MAP3K2 3682:MAP3K1 3656:MAPK14 3651:MAPK13 3646:MAPK11 3634:MAPK10 3612:MAPK15 3607:MAPK12 3499:CDC2L1 3474:CDC2L5 3149:SNF1LK 2974:CAMK2G 2969:CAMK2D 2964:CAMK2B 2959:CAMK2A 2949:CAMK1G 2944:CAMK1D 2939:CAMK1B 2934:CAMK1A 2788:PRKCB1 2725:PRKACA 2720:PRKACB 2715:PRKACG 2691:IKBKAP 2517:BCKDHB 2512:BCKDHA 2486:PRKAG3 2481:PRKAG2 2476:PRKAG1 2466:PRKAB2 2461:PRKAB1 2451:PRKAA2 2446:PRKAA1 2291:STK38L 2120:  2110:  2077:  2049:Nature 2034:  2024:  1991:  1984:528928 1981:  1948:  1940:  1914:Nature 1903:  1868:  1835:  1828:139241 1825:  1782:  1753:  1743:  1700:  1690:  1657:  1622:  1614:  1585:  1550:  1515:  1469:  1459:  1445:: 54. 1417:  1407:  1399:  1340:  1180:PRKAG1 1176:PRKAG2 1113:PRKAB2 1109:enzyme 1107:is an 1063:search 1061:PubMed 936:Q6PAM0 917:O43741 846:108097 813:Entrez 587:BioGPS 274:1q21.1 190:PRKAB2 166:602741 149:PRKAB2 22:PRKAB2 4383:is a 4234:Types 3990:MAP2K 3924:ACVR1 3917:BMPR2 3902:BMPR1 3827:GSK-3 3668:MAP3K 3629:MAPK9 3624:MAPK8 3602:MAPK7 3597:MAPK6 3592:MAPK4 3587:MAPK3 3582:MAPK1 3494:PFTK1 3489:PCTK3 3484:PCTK2 3479:PCTK1 3469:CDK12 3464:CDK10 3439:CDKL5 3419:CDKL2 3296:STK19 3291:EEF2K 3272:PHKG2 3267:PHKG1 3257:PHKA2 3252:PHKA1 3233:MYLK4 3228:MYLK3 3223:MYLK2 3199:DCLK1 3194:Titin 3184:TRIB3 3179:TRIB2 3174:TRIB1 3164:TSSK2 3144:STK40 3129:PSKH1 3124:PRKD3 3119:PRKD2 3099:PHKG2 3094:PHKG1 3084:OBSCN 3079:NUAK2 3074:NUAK1 3069:MKNK2 3064:MKNK1 3054:MARK4 3049:MARK3 3044:MARK2 3039:MARK1 3019:STK11 3014:DAPK3 3009:DAPK2 3004:DAPK1 2999:CHEK2 2994:CHEK1 2979:CAMK4 2954:CAMK2 2929:CAMK1 2924:BRSK2 2818:PRKCQ 2813:PRKCI 2808:PRKCG 2803:PRKCH 2798:PRKCE 2793:PRKCD 2754:PRKG1 2686:IKBKG 2681:IKBKE 2630:STK10 2625:FASTK 2551:IDH3G 2546:IDH3B 2541:IDH3A 2507:BCKDK 2301:ROCK1 2286:STK38 2281:MAST2 2276:MAST1 2271:LATS2 2266:LATS1 1946:S2CID 1746:64988 1620:S2CID 1202:CHD1L 1187:CHD1L 1174:with 806:Mouse 801:Human 772:Amigo 439:Mouse 432:Human 379:Start 314:Mouse 278:Start 211:Human 182:38046 4385:stub 4377:gene 4326:list 4319:EC7 4313:list 4306:EC6 4300:list 4293:EC5 4287:list 4280:EC4 4274:list 4267:EC3 4261:list 4254:EC2 4248:list 4241:EC1 3817:TPK1 3793:CDC7 3751:MLKs 3744:KSR2 3739:KSR1 3734:BRAF 3729:ARAF 3724:RAFs 3459:CDK9 3454:CDK8 3449:CDK7 3444:CDK6 3434:CDK5 3429:CDK4 3424:CDK3 3414:CDK2 3409:CDK1 3390:PLK4 3385:PLK3 3380:PLK2 3375:PLK1 3330:PLK4 3325:PLK3 3320:PLK2 3315:PLK1 3262:PHKB 3218:MYLK 3189:TRIO 3159:SPEG 3154:SNRK 3114:PKD1 3109:PIM2 3104:PIM1 3089:PASK 3059:MELK 2989:CASK 2984:MLCK 2905:GRK6 2900:GRK5 2895:GRK4 2833:PKN3 2828:PKN2 2730:PRKY 2676:TBK1 2671:IKK2 2666:CHUK 2570:STK4 2536:IDH2 2421:PDK4 2416:PDK3 2411:PDK2 2406:PDK1 2385:WEE1 2380:Wee1 2348:mTOR 2336:AKT3 2331:AKT2 2326:AKT1 2316:SGK3 2311:SGK2 2178:2f15 2118:PMID 2075:PMID 2032:PMID 1989:PMID 1938:PMID 1901:PMID 1866:PMID 1833:PMID 1780:PMID 1751:PMID 1698:PMID 1655:PMID 1612:PMID 1583:PMID 1548:PMID 1513:PMID 1467:PMID 1415:PMID 1397:ISSN 1338:PMID 1178:and 1141:and 1116:gene 827:5565 422:Bgee 370:Band 331:Chr. 269:Band 228:Chr. 162:OMIM 119:4REW 115:4RER 111:4EAJ 107:4EAI 103:4CFH 99:2YA3 95:2Y8Q 91:2Y8L 87:2V9J 83:2V92 79:2V8Q 75:2F15 56:RCSB 53:PDBe 3822:TTK 3786:ZAK 2363:HRI 2358:PKR 2306:SGK 2296:CIT 2108:PMC 2100:doi 2065:doi 2053:441 2022:PMC 2014:doi 1979:PMC 1971:doi 1930:doi 1918:428 1891:doi 1858:doi 1823:PMC 1813:doi 1772:doi 1741:PMC 1731:doi 1688:PMC 1680:doi 1676:346 1645:doi 1641:273 1604:doi 1600:409 1573:doi 1538:doi 1534:271 1503:doi 1499:271 1457:PMC 1447:doi 1405:PMC 1389:doi 1385:346 1328:doi 1324:271 1197:: 392:End 291:End 194:OMA 170:MGI 46:PDB 4430:: 2472:Îł 2457:β 2442:α 2230:EC 2224:: 2116:. 2106:. 2094:. 2090:. 2073:. 2063:. 2051:. 2047:. 2030:. 2020:. 2010:16 2008:. 2004:. 1987:. 1977:. 1967:14 1965:. 1961:. 1944:. 1936:. 1928:. 1916:. 1899:. 1887:36 1885:. 1881:. 1864:. 1854:16 1852:. 1848:. 1831:. 1821:. 1811:. 1801:99 1799:. 1795:. 1778:. 1768:93 1766:. 1749:. 1739:. 1729:. 1719:98 1717:. 1713:. 1696:. 1686:. 1674:. 1670:. 1653:. 1639:. 1635:. 1618:. 1610:. 1598:. 1581:. 1567:. 1563:. 1546:. 1532:. 1528:. 1511:. 1497:. 1493:. 1465:. 1455:. 1441:. 1437:. 1413:. 1403:. 1395:. 1383:. 1379:. 1367:^ 1350:^ 1336:. 1322:. 1318:. 1299:. 1281:. 1252:^ 1231:^ 1182:. 1118:. 774:/ 398:bp 385:bp 297:bp 284:bp 192:; 188:: 184:; 180:: 176:; 172:: 168:; 164:: 117:, 113:, 109:, 105:, 101:, 97:, 93:, 89:, 85:, 81:, 77:, 4416:e 4409:t 4402:v 4391:. 4342:: 4328:) 4324:( 4315:) 4311:( 4302:) 4298:( 4289:) 4285:( 4276:) 4272:( 4263:) 4259:( 4250:) 4246:( 4070:e 4063:t 4056:v 3879:- 3862:- 3845:- 2648:- 2228:( 2214:e 2207:t 2200:v 2153:e 2146:t 2139:v 2124:. 2102:: 2096:3 2081:. 2067:: 2059:: 2038:. 2016:: 1995:. 1973:: 1952:. 1932:: 1924:: 1907:. 1893:: 1872:. 1860:: 1839:. 1815:: 1807:: 1786:. 1774:: 1757:. 1733:: 1725:: 1704:. 1682:: 1661:. 1647:: 1626:. 1606:: 1589:. 1575:: 1569:6 1554:. 1540:: 1519:. 1505:: 1473:. 1449:: 1443:6 1421:. 1391:: 1361:. 1344:. 1330:: 1303:. 1285:. 316:) 213:) 196::

Index


PDB
PDBe
RCSB
2F15
2V8Q
2V92
2V9J
2Y8L
2Y8Q
2YA3
4CFH
4EAI
4EAJ
4RER
4REW
Aliases
PRKAB2
OMIM
602741
MGI
1336185
HomoloGene
38046
GeneCards
PRKAB2
OMA
PRKAB2 - orthologs
Human
Chromosome 1 (human)

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