Knowledge (XXG)

PRKAG1

Source 📝

338: 315: 212: 237: 2194: 2179: 2164: 2149: 589: 29: 344: 243: 4371: 4391: 55: 1192:(AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus 1898:
Zidovetzki R, Wang JL, Chen P, Jeyaseelan R, Hofman F (July 1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways".
2047:
Minokoshi Y, Alquier T, Furukawa N, Kim YB, Lee A, Xue B, Mu J, Foufelle F, Ferré P, Birnbaum MJ, Stuck BJ, Kahn BB (April 2004). "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus".
1795:
Stapleton D, Woollatt E, Mitchelhill KI, Nicholl JK, Fernandez CS, Michell BJ, Witters LA, Power DA, Sutherland GR, Kemp BE (June 1997). "AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location".
2234: 2519: 1868:
Reinton N, Haugen TB, Orstavik S, Skålhegg BS, Hansson V, Jahnsen T, Taskén K (April 1998). "The gene encoding the C gamma catalytic subunit of cAMP-dependent protein kinase is a transcribed retroposon".
2193: 2178: 2163: 2148: 2227: 1928:
Mayne M, Bratanich AC, Chen P, Rana F, Nath A, Power C (1998). "HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease".
1532:"Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis--representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase" 2220: 351: 250: 2427: 2975: 3814: 2278: 3923: 2661: 2548: 887: 173: 2936: 868: 3909: 3374: 2265: 2247: 4465: 4011: 3892: 4436: 3598: 2467: 4455: 3662: 2637: 2128: 2103:
provides an overview of all the structure information available in the PDB for Human 5'-AMP-activated protein kinase subunit gamma-1 (PRKAG1)
1317: 1299: 3918: 1618:
Hofmann B, Nishanian P, Fan J, Nguyen T, Fahey JL (July 1994). "HIV Gag p17 protein impairs proliferation of normal lymphocytes in vitro".
337: 52: 2452: 3975: 3650: 1107: 1114: 314: 4090: 2907: 2897: 2582: 1335:
Stapleton D, Mitchelhill KI, Gao G, Widmer J, Michell BJ, Teh T, House CM, Fernandez CS, Cox T, Witters LA, Kemp BE (January 1996).
1835:"The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases" 3589: 1420: 3858: 3530: 2892: 2883: 1286: 1265: 236: 211: 4246: 1282: 1649:"Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro" 3273: 2770: 2761: 2418: 2364: 4361: 1261: 2461: 1189: 153: 1229: 350: 249: 2212: 4429: 3485: 3303: 2799: 343: 242: 4231: 4347: 4334: 4321: 4308: 4295: 4282: 4269: 3475: 3470: 3465: 3455: 3450: 3445: 3435: 3230: 3005: 2601: 2121: 1567:"Human immunodeficiency virus proteins induce the inhibitory cAMP/protein kinase A pathway in normal lymphocytes" 1489:"HIV inhibits the early steps of lymphocyte activation, including initiation of inositol phospholipid metabolism" 4241: 4195: 4138: 3698: 3689: 3640: 2406: 2251: 932: 161: 2202:: CRYSTAL STRUCTURE OF A CBS DOMAIN PAIR FROM THE REGULATORY GAMMA1 SUBUNIT OF HUMAN AMPK IN COMPLEX WITH AMP 2187:: CRYSTAL STRUCTURE OF A CBS DOMAIN PAIR FROM THE REGULATORY GAMMA1 SUBUNIT OF HUMAN AMPK IN COMPLEX WITH AMP 2172:: CRYSTAL STRUCTURE OF A CBS DOMAIN PAIR FROM THE REGULATORY GAMMA1 SUBUNIT OF HUMAN AMPK IN COMPLEX WITH AMP 2157:: CRYSTAL STRUCTURE OF A CBS DOMAIN PAIR FROM THE REGULATORY GAMMA1 SUBUNIT OF HUMAN AMPK IN COMPLEX WITH AMP 4143: 3998: 3421: 1754:"The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix" 913: 1197: 4422: 4164: 4083: 2697: 225: 4236: 1967:"Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding" 1439:"Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding" 3264: 2114: 2057: 1578: 1213: 1684:"Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits" 140: 4200: 1065: 1061: 1006: 1002: 3772: 1376:
Gao G, Fernandez CS, Stapleton D, Auster AS, Widmer J, Dyck JR, Kemp BE, Witters LA (April 1996).
4460: 4133: 3875: 3829: 2081: 2035: 1953: 1821: 1518: 185: 1090: 1069: 1035: 1014: 1010: 3135: 2844: 2073: 2027: 1992: 1945: 1916: 1886: 1856: 1813: 1783: 1740: 1705: 1670: 1635: 1606: 1553: 1510: 1464: 1399: 1358: 1201: 133: 45: 4406: 4179: 4174: 4148: 4076: 3728: 2970: 2960: 2955: 2873: 2864: 2794: 2785: 2731: 2722: 2379: 2065: 2017: 2004:
Hamilton SR, Stapleton D, O'Donnell JB, Kung JT, Dalal SR, Kemp BE, Witters LA (July 2001).
1982: 1974: 1937: 1908: 1878: 1846: 1805: 1773: 1765: 1730: 1695: 1660: 1627: 1596: 1586: 1543: 1500: 1454: 1446: 1389: 1348: 588: 430: 361: 305: 260: 181: 4226: 4210: 4123: 3554: 2625: 2620: 2615: 1217: 1193: 405: 2061: 1582: 28: 4375: 4264: 4205: 1987: 1966: 1459: 1438: 1378:"Non-catalytic beta- and gamma-subunit isoforms of the 5'-AMP-activated protein kinase" 2022: 2005: 1809: 1778: 1753: 1682:
Dyck JR, Gao G, Widmer J, Stapleton D, Fernandez CS, Kemp BE, Witters LA (July 1996).
802: 797: 792: 787: 782: 777: 772: 767: 762: 757: 752: 747: 742: 737: 721: 716: 711: 706: 701: 696: 680: 675: 670: 665: 660: 655: 650: 645: 640: 635: 630: 4449: 4402: 4169: 4128: 2678: 2610: 2100: 1631: 1601: 1566: 1487:
Hofmann B, Nishanian P, Baldwin RL, Insixiengmay P, Nel A, Fahey JL (December 1990).
617: 2039: 1957: 1825: 1769: 1647:
Woods A, Cheung PC, Smith FC, Davison MD, Scott J, Beri RK, Carling D (April 1996).
1522: 4118: 3549: 2374: 2085: 423: 202: 165: 2006:"An activating mutation in the gamma1 subunit of the AMP-activated protein kinase" 1421:"Entrez Gene: PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit" 1505: 1488: 189: 4342: 4277: 4113: 3755: 3387: 3327: 3210: 3130: 2854: 1978: 1450: 1322:
National Center for Biotechnology Information, U.S. National Library of Medicine
1304:
National Center for Biotechnology Information, U.S. National Library of Medicine
1209: 4370: 1571:
Proceedings of the National Academy of Sciences of the United States of America
506: 3843: 2317: 1205: 322: 219: 169: 1851: 1834: 1700: 1683: 1665: 1648: 4316: 4290: 2804: 1912: 1719:"Normalization and subtraction: two approaches to facilitate gene discovery" 1591: 1394: 1377: 832: 566: 444: 389: 376: 288: 275: 177: 2077: 2031: 1996: 1882: 1530:
Beebe SJ, Oyen O, Sandberg M, Frøysa A, Hansson V, Jahnsen T (March 1990).
1468: 1949: 1920: 1890: 1860: 1817: 1787: 1744: 1709: 1674: 1639: 1610: 1557: 1514: 1403: 1362: 1353: 1336: 1154: 1149: 3160: 3055: 3050: 3045: 1548: 1531: 1138: 977: 958: 2069: 1565:
Hofmann B, Nishanian P, Nguyen T, Insixiengmay P, Fahey JL (July 1993).
3819: 3797: 3792: 3782: 3777: 3579: 3574: 3569: 3564: 3559: 3544: 3539: 3190: 3155: 2394: 2389: 2384: 1735: 1718: 944: 899: 1941: 110: 106: 102: 98: 94: 90: 86: 82: 78: 74: 4329: 4099: 4049: 4044: 4039: 4034: 4029: 4024: 4019: 3970: 3965: 3960: 3955: 3950: 3933: 3928: 3802: 3787: 3738: 3733: 3718: 3713: 3708: 3703: 3677: 3672: 3667: 3655: 3633: 3628: 3520: 3495: 3170: 2995: 2990: 2985: 2980: 2965: 2809: 2746: 2741: 2736: 2712: 2538: 2533: 2507: 2502: 2487: 2482: 2472: 2312: 2243: 1237: 1233: 1170: 1122: 854: 4390: 1752:
Swingler S, Gallay P, Camaur D, Song J, Abo A, Trono D (June 1997).
1204:(HMGCR), key enzymes involved in regulating de novo biosynthesis of 144:, AMPKG, protein kinase AMP-activated non-catalytic subunit gamma 1 4303: 3945: 3938: 3848: 3745: 3645: 3623: 3618: 3613: 3608: 3603: 3515: 3510: 3505: 3500: 3490: 3460: 3440: 3317: 3312: 3293: 3288: 3278: 3254: 3249: 3244: 3220: 3215: 3205: 3200: 3195: 3185: 3165: 3150: 3145: 3140: 3120: 3115: 3105: 3100: 3095: 3090: 3085: 3075: 3070: 3065: 3060: 3040: 3035: 3030: 3025: 3020: 3015: 3000: 2950: 2945: 2839: 2834: 2829: 2824: 2819: 2814: 2775: 2707: 2702: 2651: 2646: 2572: 2567: 2562: 2528: 2520:
3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase
2322: 2307: 2302: 2297: 2292: 2287: 1965:
Cheung PC, Salt IP, Davies SP, Hardie DG, Carling D (March 2000).
1437:
Cheung PC, Salt IP, Davies SP, Hardie DG, Carling D (March 2000).
817: 813: 4398: 3838: 3765: 3760: 3750: 3723: 3480: 3430: 3411: 3406: 3401: 3396: 3351: 3346: 3341: 3336: 3283: 3239: 3180: 3175: 3125: 3110: 3080: 3010: 2926: 2921: 2916: 2849: 2751: 2692: 2687: 2591: 2557: 2442: 2437: 2432: 2401: 2369: 2357: 2352: 2347: 2337: 2332: 1212:. This subunit is one of the gamma regulatory subunits of AMPK. 1188:
The protein encoded by this gene is a regulatory subunit of the
1177: 157: 4072: 3996: 3372: 2263: 2216: 2110: 597: 3807: 2342: 2327: 2106: 4068: 413: 4410: 788:
regulation of signal transduction by p53 class mediator
803:
regulation of protein serine/threonine kinase activity
4359: 578: 4255: 4219: 4188: 4157: 4106: 4010: 3908: 3891: 3874: 3857: 3828: 3688: 3588: 3529: 3420: 3386: 3326: 3302: 3263: 3229: 2935: 2906: 2882: 2863: 2784: 2760: 2721: 2677: 2660: 2636: 2600: 2581: 2547: 2518: 2451: 2417: 2277: 1833:Chen P, Mayne M, Power C, Nath A (September 1997). 1083: 1054: 1028: 995: 1717:Bonaldo MF, Lennon G, Soares MB (September 1996). 1337:"Mammalian AMP-activated protein kinase subfamily" 1278: 1276: 1274: 1257: 1255: 1253: 360: 259: 666:cAMP-dependent protein kinase regulator activity 1167:5'-AMP-activated protein kinase subunit gamma-1 16:Protein-coding gene in the species Homo sapiens 1432: 1430: 1283:GRCm38: Ensembl release 89: ENSMUSG00000067713 1202:beta-hydroxy beta-methylglutaryl-CoA reductase 783:positive regulation of protein kinase activity 4430: 4084: 2279:Non-specific serine/threonine protein kinases 2228: 2122: 8: 1262:GRCh38: Ensembl release 89: ENSG00000181929 707:nucleotide-activated protein kinase complex 4437: 4423: 4091: 4077: 4069: 4007: 3993: 3383: 3369: 2662:Goodpasture-antigen-binding protein kinase 2274: 2260: 2235: 2221: 2213: 2129: 2115: 2107: 828: 613: 401: 300: 197: 63: 3375:Serine/threonine-specific protein kinases 2549:(isocitrate dehydrogenase (NADP+)) kinase 2266:Serine/threonine-specific protein kinases 2248:Serine/threonine-specific protein kinases 2021: 1986: 1850: 1777: 1734: 1699: 1664: 1600: 1590: 1547: 1504: 1458: 1393: 1352: 537:fetal liver hematopoietic progenitor cell 3910:Receptor protein serine/threonine kinase 1415: 1413: 4366: 3893:Low-density-lipoprotein receptor kinase 2144: 1249: 1216:transcript variants encoding distinct 758:positive regulation of gene expression 641:cAMP-dependent protein kinase activity 18: 2638:Fas-activated serine/threonine kinase 651:AMP-activated protein kinase activity 365: 326: 321: 264: 223: 218: 7: 4387: 4385: 3919:Bone morphogenetic protein receptors 1901:AIDS Research and Human Retroviruses 2453:Dephospho-(reductase kinase) kinase 1839:The Journal of Biological Chemistry 1688:The Journal of Biological Chemistry 1653:The Journal of Biological Chemistry 1382:The Journal of Biological Chemistry 1341:The Journal of Biological Chemistry 4409:. You can help Knowledge (XXG) by 2908:G-protein coupled receptor kinases 1080: 1051: 1025: 992: 968: 949: 923: 904: 878: 859: 583: 501: 439: 418: 14: 2898:Beta adrenergic receptor kinase-2 2583:(tyrosine 3-monooxygenase) kinase 1173:that in humans is encoded by the 4389: 4369: 3590:Mitogen-activated protein kinase 2192: 2177: 2162: 2147: 1632:10.1097/00002030-199407000-00025 748:regulation of glycolytic process 587: 349: 342: 336: 313: 248: 241: 235: 210: 27: 3976:Anti-Müllerian hormone receptor 3859:(acetyl-CoA carboxylase) kinase 3531:(RNA-polymerase)-subunit kinase 2893:Beta adrenergic receptor kinase 2884:Beta adrenergic receptor kinase 1770:10.1128/JVI.71.6.4372-4377.1997 763:fatty acid biosynthetic process 4466:Human chromosome 12 gene stubs 3599:Extracellular signal-regulated 598:More reference expression data 567:More reference expression data 1: 3663:P38 mitogen-activated protein 2762:cGMP-dependent protein kinase 2723:cAMP-dependent protein kinase 2419:Pyruvate dehydrogenase kinase 2365:Ataxia telangiectasia mutated 2023:10.1016/S0014-5793(01)02602-3 1810:10.1016/S0014-5793(97)00569-3 681:adenyl ribonucleotide binding 334: 233: 4456:Genes on human chromosome 12 2462:AMP-activated protein kinase 1506:10.4049/jimmunol.145.11.3699 1190:AMP-activated protein kinase 793:regulation of macroautophagy 743:fatty acid metabolic process 3377:(EC 2.7.11.21-EC 2.7.11.30) 4482: 4384: 3304:Elongation factor 2 kinase 2268:(EC 2.7.11.1-EC 2.7.11.20) 4247:Michaelis–Menten kinetics 4006: 3992: 3699:MAP kinase kinase kinases 3382: 3368: 3231:Myosin light-chain kinase 2937:Ca2+/calmodulin-dependent 2602:Myosin-heavy-chain kinase 2273: 2259: 2142: 1979:10.1042/0264-6021:3460659 1451:10.1042/0264-6021:3460659 1318:"Mouse PubMed Reference:" 1300:"Human PubMed Reference:" 1228:PRKAG1 has been shown to 1153: 1148: 1144: 1137: 1121: 1102: 1087: 1058: 1047: 1032: 999: 988: 975: 971: 956: 952: 943: 930: 926: 911: 907: 898: 885: 881: 866: 862: 853: 838: 831: 827: 811: 616: 612: 595: 586: 577: 564: 513: 504: 451: 442: 412: 404: 400: 383: 370: 333: 312: 303: 299: 282: 269: 232: 209: 200: 196: 151: 148: 138: 131: 126: 71: 66: 49: 44: 39: 35: 26: 21: 4139:Diffusion-limited enzyme 3999:Dual-specificity kinases 1973:. 346 Pt 3 (3): 659–69. 1852:10.1074/jbc.272.36.22385 1701:10.1074/jbc.271.30.17798 1666:10.1074/jbc.271.48.30517 1445:. 346 Pt 3 (3): 659–69. 1115:Chr 15: 98.71 – 98.73 Mb 3422:Cyclin-dependent kinase 1971:The Biochemical Journal 1913:10.1089/aid.1998.14.825 1592:10.1073/pnas.90.14.6676 1536:Molecular Endocrinology 1443:The Biochemical Journal 1395:10.1074/jbc.271.15.8675 753:protein phosphorylation 636:protein kinase activity 549:external carotid artery 545:internal carotid artery 1883:10.1006/geno.1998.5240 1198:acetyl-CoA carboxylase 671:protein kinase binding 475:triceps brachii muscle 367:15 F1|15 54.73 cM 4232:Eadie–Hofstee diagram 4165:Allosteric regulation 1930:Neuroimmunomodulation 1493:Journal of Immunology 1354:10.1074/jbc.271.2.611 1214:Alternatively spliced 1108:Chr 12: 49 – 49.02 Mb 712:extracellular exosome 328:Chromosome 15 (mouse) 226:Chromosome 12 (human) 4242:Lineweaver–Burk plot 3265:Phosphorylase kinase 1549:10.1210/mend-4-3-465 1220:have been observed. 463:right adrenal cortex 455:gastrocnemius muscle 67:List of PDB id codes 40:Available structures 2070:10.1038/nature02440 2062:2004Natur.428..569M 1758:Journal of Virology 1583:1993PNAS...90.6676H 798:import into nucleus 778:signal transduction 479:left adrenal cortex 459:islet of Langerhans 4397:This article on a 4201:Enzyme superfamily 4134:Enzyme promiscuity 3876:Tropomyosin kinase 3830:Tau-protein kinase 1736:10.1101/gr.6.9.791 933:ENSMUSG00000067713 731:Biological process 690:Cellular component 631:nucleotide binding 624:Molecular function 471:left adrenal gland 190:PRKAG1 - orthologs 4418: 4417: 4357: 4356: 4066: 4065: 4062: 4061: 4058: 4057: 3988: 3987: 3984: 3983: 3364: 3363: 3360: 3359: 2845:Protein kinase N1 2800:Protein kinase Cζ 2210: 2209: 1942:10.1159/000026336 1694:(30): 17798–803. 1164: 1163: 1160: 1159: 1133: 1132: 1098: 1097: 1077: 1076: 1043: 1042: 1022: 1021: 984: 983: 965: 964: 939: 938: 920: 919: 894: 893: 875: 874: 823: 822: 608: 607: 604: 603: 573: 572: 560: 559: 498: 497: 396: 395: 295: 294: 122: 121: 118: 117: 50:Ortholog search: 4473: 4439: 4432: 4425: 4393: 4386: 4374: 4373: 4365: 4237:Hanes–Woolf plot 4180:Enzyme activator 4175:Enzyme inhibitor 4149:Enzyme catalysis 4093: 4086: 4079: 4070: 4008: 3994: 3641:C-Jun N-terminal 3384: 3370: 2874:Rhodopsin kinase 2865:Rhodopsin kinase 2795:Protein kinase C 2786:Protein kinase C 2771:Protein kinase G 2732:Protein kinase A 2343:Protein kinase B 2275: 2261: 2237: 2230: 2223: 2214: 2196: 2181: 2166: 2151: 2131: 2124: 2117: 2108: 2089: 2056:(6982): 569–74. 2043: 2025: 2000: 1990: 1961: 1924: 1894: 1864: 1854: 1829: 1791: 1781: 1748: 1738: 1713: 1703: 1678: 1668: 1659:(17): 10282–90. 1643: 1614: 1604: 1594: 1561: 1551: 1526: 1508: 1499:(11): 3699–705. 1473: 1472: 1462: 1434: 1425: 1424: 1417: 1408: 1407: 1397: 1373: 1367: 1366: 1356: 1332: 1326: 1325: 1314: 1308: 1307: 1296: 1290: 1280: 1269: 1259: 1196:and inactivates 1146: 1145: 1117: 1110: 1093: 1081: 1072: 1052: 1048:RefSeq (protein) 1038: 1026: 1017: 993: 969: 950: 924: 905: 879: 860: 829: 738:lipid metabolism 614: 600: 591: 584: 569: 509: 507:Top expressed in 502: 447: 445:Top expressed in 440: 419: 402: 392: 379: 368: 353: 346: 340: 329: 317: 301: 291: 278: 267: 252: 245: 239: 228: 214: 198: 192: 143: 136: 113: 64: 58: 37: 36: 31: 19: 4481: 4480: 4476: 4475: 4474: 4472: 4471: 4470: 4446: 4445: 4444: 4443: 4382: 4380: 4368: 4360: 4358: 4353: 4265:Oxidoreductases 4251: 4227:Enzyme kinetics 4215: 4211:List of enzymes 4184: 4153: 4124:Catalytic triad 4102: 4097: 4067: 4054: 4002: 3980: 3904: 3887: 3870: 3853: 3824: 3684: 3584: 3555:P70-S6 Kinase 1 3525: 3416: 3378: 3356: 3322: 3298: 3259: 3225: 2931: 2902: 2878: 2859: 2780: 2756: 2717: 2673: 2656: 2632: 2626:Aurora C kinase 2621:Aurora B kinase 2616:Aurora A kinase 2596: 2577: 2543: 2514: 2447: 2413: 2269: 2255: 2241: 2211: 2206: 2203: 2197: 2188: 2182: 2173: 2167: 2158: 2152: 2138: 2135: 2097: 2092: 2046: 2003: 1964: 1936:(3–4): 184–92. 1927: 1897: 1867: 1845:(36): 22385–8. 1832: 1794: 1751: 1723:Genome Research 1716: 1681: 1646: 1617: 1577:(14): 6676–80. 1564: 1529: 1486: 1482: 1480:Further reading 1477: 1476: 1436: 1435: 1428: 1419: 1418: 1411: 1388:(15): 8675–81. 1375: 1374: 1370: 1334: 1333: 1329: 1316: 1315: 1311: 1298: 1297: 1293: 1281: 1272: 1260: 1251: 1246: 1226: 1186: 1155:View/Edit Mouse 1150:View/Edit Human 1113: 1106: 1103:Location (UCSC) 1089: 1068: 1064: 1060: 1034: 1013: 1009: 1005: 1001: 914:ENSG00000181929 807: 768:spermatogenesis 726: 685: 661:protein binding 596: 565: 556: 551: 547: 543: 539: 535: 533:right ventricle 531: 527: 523: 519: 505: 494: 489: 485: 483:muscle of thigh 481: 477: 473: 469: 465: 461: 457: 443: 387: 374: 366: 356: 355: 354: 347: 327: 304:Gene location ( 286: 273: 265: 255: 254: 253: 246: 224: 201:Gene location ( 152: 139: 132: 73: 51: 17: 12: 11: 5: 4479: 4477: 4469: 4468: 4463: 4458: 4448: 4447: 4442: 4441: 4434: 4427: 4419: 4416: 4415: 4394: 4379: 4378: 4355: 4354: 4352: 4351: 4338: 4325: 4312: 4299: 4286: 4273: 4259: 4257: 4253: 4252: 4250: 4249: 4244: 4239: 4234: 4229: 4223: 4221: 4217: 4216: 4214: 4213: 4208: 4203: 4198: 4192: 4190: 4189:Classification 4186: 4185: 4183: 4182: 4177: 4172: 4167: 4161: 4159: 4155: 4154: 4152: 4151: 4146: 4141: 4136: 4131: 4126: 4121: 4116: 4110: 4108: 4104: 4103: 4098: 4096: 4095: 4088: 4081: 4073: 4064: 4063: 4060: 4059: 4056: 4055: 4053: 4052: 4047: 4042: 4037: 4032: 4027: 4022: 4016: 4014: 4004: 4003: 3997: 3990: 3989: 3986: 3985: 3982: 3981: 3979: 3978: 3973: 3968: 3963: 3958: 3953: 3948: 3943: 3942: 3941: 3936: 3931: 3926: 3915: 3913: 3912:(EC 2.7.11.30) 3906: 3905: 3903: 3902: 3898: 3896: 3895:(EC 2.7.11.29) 3889: 3888: 3886: 3885: 3881: 3879: 3878:(EC 2.7.11.28) 3872: 3871: 3869: 3868: 3864: 3862: 3861:(EC 2.7.11.27) 3855: 3854: 3852: 3851: 3846: 3841: 3835: 3833: 3832:(EC 2.7.11.26) 3826: 3825: 3823: 3822: 3817: 3812: 3811: 3810: 3805: 3800: 3795: 3790: 3785: 3780: 3770: 3769: 3768: 3763: 3758: 3753: 3743: 3742: 3741: 3736: 3731: 3726: 3721: 3716: 3711: 3706: 3695: 3693: 3692:(EC 2.7.11.25) 3686: 3685: 3683: 3682: 3681: 3680: 3675: 3670: 3660: 3659: 3658: 3653: 3648: 3638: 3637: 3636: 3631: 3626: 3621: 3616: 3611: 3606: 3595: 3593: 3592:(EC 2.7.11.24) 3586: 3585: 3583: 3582: 3577: 3572: 3567: 3562: 3557: 3552: 3547: 3542: 3536: 3534: 3533:(EC 2.7.11.23) 3527: 3526: 3524: 3523: 3518: 3513: 3508: 3503: 3498: 3493: 3488: 3483: 3478: 3473: 3468: 3463: 3458: 3453: 3448: 3443: 3438: 3433: 3427: 3425: 3424:(EC 2.7.11.22) 3418: 3417: 3415: 3414: 3409: 3404: 3399: 3393: 3391: 3390:(EC 2.7.11.21) 3380: 3379: 3373: 3366: 3365: 3362: 3361: 3358: 3357: 3355: 3354: 3349: 3344: 3339: 3333: 3331: 3330:(EC 2.7.11.21) 3324: 3323: 3321: 3320: 3315: 3309: 3307: 3306:(EC 2.7.11.20) 3300: 3299: 3297: 3296: 3291: 3286: 3281: 3276: 3270: 3268: 3267:(EC 2.7.11.19) 3261: 3260: 3258: 3257: 3252: 3247: 3242: 3236: 3234: 3233:(EC 2.7.11.18) 3227: 3226: 3224: 3223: 3218: 3213: 3208: 3203: 3198: 3193: 3188: 3183: 3178: 3173: 3168: 3163: 3158: 3153: 3148: 3143: 3138: 3133: 3128: 3123: 3118: 3113: 3108: 3103: 3098: 3093: 3088: 3083: 3078: 3073: 3068: 3063: 3058: 3053: 3048: 3043: 3038: 3033: 3028: 3023: 3018: 3013: 3008: 3003: 2998: 2993: 2988: 2983: 2978: 2973: 2968: 2963: 2958: 2953: 2948: 2942: 2940: 2939:(EC 2.7.11.17) 2933: 2932: 2930: 2929: 2924: 2919: 2913: 2911: 2910:(EC 2.7.11.16) 2904: 2903: 2901: 2900: 2895: 2889: 2887: 2886:(EC 2.7.11.15) 2880: 2879: 2877: 2876: 2870: 2868: 2867:(EC 2.7.11.14) 2861: 2860: 2858: 2857: 2852: 2847: 2842: 2837: 2832: 2827: 2822: 2817: 2812: 2807: 2802: 2797: 2791: 2789: 2788:(EC 2.7.11.13) 2782: 2781: 2779: 2778: 2773: 2767: 2765: 2764:(EC 2.7.11.12) 2758: 2757: 2755: 2754: 2749: 2744: 2739: 2734: 2728: 2726: 2725:(EC 2.7.11.11) 2719: 2718: 2716: 2715: 2710: 2705: 2700: 2695: 2690: 2684: 2682: 2681:(EC 2.7.11.10) 2675: 2674: 2672: 2671: 2667: 2665: 2658: 2657: 2655: 2654: 2649: 2643: 2641: 2634: 2633: 2631: 2630: 2629: 2628: 2623: 2618: 2607: 2605: 2598: 2597: 2595: 2594: 2588: 2586: 2579: 2578: 2576: 2575: 2570: 2565: 2560: 2554: 2552: 2545: 2544: 2542: 2541: 2536: 2531: 2525: 2523: 2516: 2515: 2513: 2512: 2511: 2510: 2505: 2500: 2492: 2491: 2490: 2485: 2477: 2476: 2475: 2470: 2458: 2456: 2449: 2448: 2446: 2445: 2440: 2435: 2430: 2424: 2422: 2415: 2414: 2412: 2411: 2410: 2409: 2399: 2398: 2397: 2392: 2387: 2382: 2372: 2367: 2362: 2361: 2360: 2355: 2350: 2340: 2335: 2330: 2325: 2320: 2315: 2310: 2305: 2300: 2295: 2290: 2284: 2282: 2271: 2270: 2264: 2257: 2256: 2242: 2240: 2239: 2232: 2225: 2217: 2208: 2207: 2205: 2204: 2198: 2191: 2189: 2183: 2176: 2174: 2168: 2161: 2159: 2153: 2146: 2143: 2140: 2139: 2136: 2134: 2133: 2126: 2119: 2111: 2105: 2104: 2096: 2095:External links 2093: 2091: 2090: 2044: 2001: 1962: 1925: 1907:(10): 825–33. 1895: 1865: 1830: 1792: 1749: 1729:(9): 791–806. 1714: 1679: 1644: 1615: 1562: 1527: 1483: 1481: 1478: 1475: 1474: 1426: 1409: 1368: 1327: 1309: 1291: 1270: 1248: 1247: 1245: 1242: 1225: 1222: 1194:phosphorylates 1185: 1182: 1162: 1161: 1158: 1157: 1152: 1142: 1141: 1135: 1134: 1131: 1130: 1128: 1126: 1119: 1118: 1111: 1104: 1100: 1099: 1096: 1095: 1085: 1084: 1078: 1075: 1074: 1056: 1055: 1049: 1045: 1044: 1041: 1040: 1030: 1029: 1023: 1020: 1019: 997: 996: 990: 986: 985: 982: 981: 973: 972: 966: 963: 962: 954: 953: 947: 941: 940: 937: 936: 928: 927: 921: 918: 917: 909: 908: 902: 896: 895: 892: 891: 883: 882: 876: 873: 872: 864: 863: 857: 851: 850: 845: 840: 836: 835: 825: 824: 821: 820: 809: 808: 806: 805: 800: 795: 790: 785: 780: 775: 773:macroautophagy 770: 765: 760: 755: 750: 745: 740: 734: 732: 728: 727: 725: 724: 719: 714: 709: 704: 699: 693: 691: 687: 686: 684: 683: 678: 673: 668: 663: 658: 653: 648: 643: 638: 633: 627: 625: 621: 620: 610: 609: 606: 605: 602: 601: 593: 592: 581: 575: 574: 571: 570: 562: 561: 558: 557: 555: 554: 550: 546: 542: 538: 534: 530: 526: 522: 518: 514: 511: 510: 499: 496: 495: 493: 492: 488: 484: 480: 476: 472: 468: 467:left ventricle 464: 460: 456: 452: 449: 448: 436: 435: 427: 416: 410: 409: 406:RNA expression 398: 397: 394: 393: 385: 381: 380: 372: 369: 364: 358: 357: 348: 341: 335: 331: 330: 325: 319: 318: 310: 309: 297: 296: 293: 292: 284: 280: 279: 271: 268: 263: 257: 256: 247: 240: 234: 230: 229: 222: 216: 215: 207: 206: 194: 193: 150: 146: 145: 137: 129: 128: 124: 123: 120: 119: 116: 115: 69: 68: 60: 59: 48: 42: 41: 33: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 4478: 4467: 4464: 4462: 4459: 4457: 4454: 4453: 4451: 4440: 4435: 4433: 4428: 4426: 4421: 4420: 4414: 4412: 4408: 4404: 4403:chromosome 12 4400: 4395: 4392: 4388: 4383: 4377: 4372: 4367: 4363: 4349: 4345: 4344: 4339: 4336: 4332: 4331: 4326: 4323: 4319: 4318: 4313: 4310: 4306: 4305: 4300: 4297: 4293: 4292: 4287: 4284: 4280: 4279: 4274: 4271: 4267: 4266: 4261: 4260: 4258: 4254: 4248: 4245: 4243: 4240: 4238: 4235: 4233: 4230: 4228: 4225: 4224: 4222: 4218: 4212: 4209: 4207: 4206:Enzyme family 4204: 4202: 4199: 4197: 4194: 4193: 4191: 4187: 4181: 4178: 4176: 4173: 4171: 4170:Cooperativity 4168: 4166: 4163: 4162: 4160: 4156: 4150: 4147: 4145: 4142: 4140: 4137: 4135: 4132: 4130: 4129:Oxyanion hole 4127: 4125: 4122: 4120: 4117: 4115: 4112: 4111: 4109: 4105: 4101: 4094: 4089: 4087: 4082: 4080: 4075: 4074: 4071: 4051: 4048: 4046: 4043: 4041: 4038: 4036: 4033: 4031: 4028: 4026: 4023: 4021: 4018: 4017: 4015: 4013: 4009: 4005: 4000: 3995: 3991: 3977: 3974: 3972: 3969: 3967: 3964: 3962: 3959: 3957: 3954: 3952: 3949: 3947: 3944: 3940: 3937: 3935: 3932: 3930: 3927: 3925: 3922: 3921: 3920: 3917: 3916: 3914: 3911: 3907: 3900: 3899: 3897: 3894: 3890: 3883: 3882: 3880: 3877: 3873: 3866: 3865: 3863: 3860: 3856: 3850: 3847: 3845: 3842: 3840: 3837: 3836: 3834: 3831: 3827: 3821: 3818: 3816: 3813: 3809: 3806: 3804: 3801: 3799: 3796: 3794: 3791: 3789: 3786: 3784: 3781: 3779: 3776: 3775: 3774: 3771: 3767: 3764: 3762: 3759: 3757: 3754: 3752: 3749: 3748: 3747: 3744: 3740: 3737: 3735: 3732: 3730: 3727: 3725: 3722: 3720: 3717: 3715: 3712: 3710: 3707: 3705: 3702: 3701: 3700: 3697: 3696: 3694: 3691: 3687: 3679: 3676: 3674: 3671: 3669: 3666: 3665: 3664: 3661: 3657: 3654: 3652: 3649: 3647: 3644: 3643: 3642: 3639: 3635: 3632: 3630: 3627: 3625: 3622: 3620: 3617: 3615: 3612: 3610: 3607: 3605: 3602: 3601: 3600: 3597: 3596: 3594: 3591: 3587: 3581: 3578: 3576: 3573: 3571: 3568: 3566: 3563: 3561: 3558: 3556: 3553: 3551: 3548: 3546: 3543: 3541: 3538: 3537: 3535: 3532: 3528: 3522: 3519: 3517: 3514: 3512: 3509: 3507: 3504: 3502: 3499: 3497: 3494: 3492: 3489: 3487: 3484: 3482: 3479: 3477: 3474: 3472: 3469: 3467: 3464: 3462: 3459: 3457: 3454: 3452: 3449: 3447: 3444: 3442: 3439: 3437: 3434: 3432: 3429: 3428: 3426: 3423: 3419: 3413: 3410: 3408: 3405: 3403: 3400: 3398: 3395: 3394: 3392: 3389: 3385: 3381: 3376: 3371: 3367: 3353: 3350: 3348: 3345: 3343: 3340: 3338: 3335: 3334: 3332: 3329: 3325: 3319: 3316: 3314: 3311: 3310: 3308: 3305: 3301: 3295: 3292: 3290: 3287: 3285: 3282: 3280: 3277: 3275: 3272: 3271: 3269: 3266: 3262: 3256: 3253: 3251: 3248: 3246: 3243: 3241: 3238: 3237: 3235: 3232: 3228: 3222: 3219: 3217: 3214: 3212: 3209: 3207: 3204: 3202: 3199: 3197: 3194: 3192: 3189: 3187: 3184: 3182: 3179: 3177: 3174: 3172: 3169: 3167: 3164: 3162: 3159: 3157: 3154: 3152: 3149: 3147: 3144: 3142: 3139: 3137: 3134: 3132: 3129: 3127: 3124: 3122: 3119: 3117: 3114: 3112: 3109: 3107: 3104: 3102: 3099: 3097: 3094: 3092: 3089: 3087: 3084: 3082: 3079: 3077: 3074: 3072: 3069: 3067: 3064: 3062: 3059: 3057: 3054: 3052: 3049: 3047: 3044: 3042: 3039: 3037: 3034: 3032: 3029: 3027: 3024: 3022: 3019: 3017: 3014: 3012: 3009: 3007: 3004: 3002: 2999: 2997: 2994: 2992: 2989: 2987: 2984: 2982: 2979: 2977: 2974: 2972: 2969: 2967: 2964: 2962: 2959: 2957: 2954: 2952: 2949: 2947: 2944: 2943: 2941: 2938: 2934: 2928: 2925: 2923: 2920: 2918: 2915: 2914: 2912: 2909: 2905: 2899: 2896: 2894: 2891: 2890: 2888: 2885: 2881: 2875: 2872: 2871: 2869: 2866: 2862: 2856: 2853: 2851: 2848: 2846: 2843: 2841: 2838: 2836: 2833: 2831: 2828: 2826: 2823: 2821: 2818: 2816: 2813: 2811: 2808: 2806: 2803: 2801: 2798: 2796: 2793: 2792: 2790: 2787: 2783: 2777: 2774: 2772: 2769: 2768: 2766: 2763: 2759: 2753: 2750: 2748: 2745: 2743: 2740: 2738: 2735: 2733: 2730: 2729: 2727: 2724: 2720: 2714: 2711: 2709: 2706: 2704: 2701: 2699: 2696: 2694: 2691: 2689: 2686: 2685: 2683: 2680: 2676: 2669: 2668: 2666: 2664:(EC 2.7.11.9) 2663: 2659: 2653: 2650: 2648: 2645: 2644: 2642: 2640:(EC 2.7.11.8) 2639: 2635: 2627: 2624: 2622: 2619: 2617: 2614: 2613: 2612: 2611:Aurora kinase 2609: 2608: 2606: 2604:(EC 2.7.11.7) 2603: 2599: 2593: 2590: 2589: 2587: 2585:(EC 2.7.11.6) 2584: 2580: 2574: 2571: 2569: 2566: 2564: 2561: 2559: 2556: 2555: 2553: 2551:(EC 2.7.11.5) 2550: 2546: 2540: 2537: 2535: 2532: 2530: 2527: 2526: 2524: 2522:(EC 2.7.11.4) 2521: 2517: 2509: 2506: 2504: 2501: 2499: 2496: 2495: 2493: 2489: 2486: 2484: 2481: 2480: 2478: 2474: 2471: 2469: 2466: 2465: 2463: 2460: 2459: 2457: 2455:(EC 2.7.11.3) 2454: 2450: 2444: 2441: 2439: 2436: 2434: 2431: 2429: 2426: 2425: 2423: 2421:(EC 2.7.11.2) 2420: 2416: 2408: 2405: 2404: 2403: 2400: 2396: 2393: 2391: 2388: 2386: 2383: 2381: 2378: 2377: 2376: 2375:EIF-2 kinases 2373: 2371: 2368: 2366: 2363: 2359: 2356: 2354: 2351: 2349: 2346: 2345: 2344: 2341: 2339: 2336: 2334: 2331: 2329: 2326: 2324: 2321: 2319: 2316: 2314: 2311: 2309: 2306: 2304: 2301: 2299: 2296: 2294: 2291: 2289: 2286: 2285: 2283: 2281:(EC 2.7.11.1) 2280: 2276: 2272: 2267: 2262: 2258: 2253: 2249: 2245: 2238: 2233: 2231: 2226: 2224: 2219: 2218: 2215: 2201: 2195: 2190: 2186: 2180: 2175: 2171: 2165: 2160: 2156: 2150: 2145: 2141: 2132: 2127: 2125: 2120: 2118: 2113: 2112: 2109: 2102: 2099: 2098: 2094: 2087: 2083: 2079: 2075: 2071: 2067: 2063: 2059: 2055: 2051: 2045: 2041: 2037: 2033: 2029: 2024: 2019: 2015: 2011: 2007: 2002: 1998: 1994: 1989: 1984: 1980: 1976: 1972: 1968: 1963: 1959: 1955: 1951: 1947: 1943: 1939: 1935: 1931: 1926: 1922: 1918: 1914: 1910: 1906: 1902: 1896: 1892: 1888: 1884: 1880: 1876: 1872: 1866: 1862: 1858: 1853: 1848: 1844: 1840: 1836: 1831: 1827: 1823: 1819: 1815: 1811: 1807: 1803: 1799: 1793: 1789: 1785: 1780: 1775: 1771: 1767: 1764:(6): 4372–7. 1763: 1759: 1755: 1750: 1746: 1742: 1737: 1732: 1728: 1724: 1720: 1715: 1711: 1707: 1702: 1697: 1693: 1689: 1685: 1680: 1676: 1672: 1667: 1662: 1658: 1654: 1650: 1645: 1641: 1637: 1633: 1629: 1626:(7): 1016–7. 1625: 1621: 1616: 1612: 1608: 1603: 1598: 1593: 1588: 1584: 1580: 1576: 1572: 1568: 1563: 1559: 1555: 1550: 1545: 1542:(3): 465–75. 1541: 1537: 1533: 1528: 1524: 1520: 1516: 1512: 1507: 1502: 1498: 1494: 1490: 1485: 1484: 1479: 1470: 1466: 1461: 1456: 1452: 1448: 1444: 1440: 1433: 1431: 1427: 1422: 1416: 1414: 1410: 1405: 1401: 1396: 1391: 1387: 1383: 1379: 1372: 1369: 1364: 1360: 1355: 1350: 1346: 1342: 1338: 1331: 1328: 1323: 1319: 1313: 1310: 1305: 1301: 1295: 1292: 1288: 1284: 1279: 1277: 1275: 1271: 1267: 1263: 1258: 1256: 1254: 1250: 1243: 1241: 1239: 1235: 1231: 1223: 1221: 1219: 1215: 1211: 1207: 1203: 1199: 1195: 1191: 1183: 1181: 1179: 1176: 1172: 1168: 1156: 1151: 1147: 1143: 1140: 1136: 1129: 1127: 1124: 1120: 1116: 1112: 1109: 1105: 1101: 1094: 1092: 1086: 1082: 1079: 1073: 1071: 1067: 1063: 1057: 1053: 1050: 1046: 1039: 1037: 1031: 1027: 1024: 1018: 1016: 1012: 1008: 1004: 998: 994: 991: 989:RefSeq (mRNA) 987: 980: 979: 974: 970: 967: 961: 960: 955: 951: 948: 946: 942: 935: 934: 929: 925: 922: 916: 915: 910: 906: 903: 901: 897: 890: 889: 884: 880: 877: 871: 870: 865: 861: 858: 856: 852: 849: 846: 844: 841: 837: 834: 830: 826: 819: 815: 810: 804: 801: 799: 796: 794: 791: 789: 786: 784: 781: 779: 776: 774: 771: 769: 766: 764: 761: 759: 756: 754: 751: 749: 746: 744: 741: 739: 736: 735: 733: 730: 729: 723: 720: 718: 715: 713: 710: 708: 705: 703: 700: 698: 695: 694: 692: 689: 688: 682: 679: 677: 674: 672: 669: 667: 664: 662: 659: 657: 654: 652: 649: 647: 644: 642: 639: 637: 634: 632: 629: 628: 626: 623: 622: 619: 618:Gene ontology 615: 611: 599: 594: 590: 585: 582: 580: 576: 568: 563: 552: 548: 544: 540: 536: 532: 528: 524: 520: 516: 515: 512: 508: 503: 500: 491:apex of heart 490: 487:right auricle 486: 482: 478: 474: 470: 466: 462: 458: 454: 453: 450: 446: 441: 438: 437: 434: 432: 428: 426: 425: 421: 420: 417: 415: 411: 407: 403: 399: 391: 386: 382: 378: 373: 363: 359: 352: 345: 339: 332: 324: 320: 316: 311: 307: 302: 298: 290: 285: 281: 277: 272: 262: 258: 251: 244: 238: 231: 227: 221: 217: 213: 208: 204: 199: 195: 191: 187: 183: 179: 175: 171: 167: 163: 159: 155: 147: 142: 135: 130: 125: 114: 112: 108: 104: 100: 96: 92: 88: 84: 80: 76: 70: 65: 62: 61: 57: 54: 47: 43: 38: 34: 30: 25: 20: 4411:expanding it 4396: 4381: 4343:Translocases 4340: 4327: 4314: 4301: 4288: 4278:Transferases 4275: 4262: 4119:Binding site 3550:P70S6 kinase 2497: 2199: 2184: 2169: 2154: 2053: 2049: 2016:(3): 163–8. 2013: 2010:FEBS Letters 2009: 1970: 1933: 1929: 1904: 1900: 1877:(2): 290–7. 1874: 1870: 1842: 1838: 1804:(3): 452–6. 1801: 1798:FEBS Letters 1797: 1761: 1757: 1726: 1722: 1691: 1687: 1656: 1652: 1623: 1619: 1574: 1570: 1539: 1535: 1496: 1492: 1442: 1385: 1381: 1371: 1347:(2): 611–4. 1344: 1340: 1330: 1321: 1312: 1303: 1294: 1227: 1224:Interactions 1187: 1174: 1166: 1165: 1088: 1066:NP_001193639 1062:NP_001193638 1059: 1033: 1007:NM_001206710 1003:NM_001206709 1000: 976: 957: 931: 912: 886: 867: 847: 842: 529:otic vesicle 525:otic placode 429: 422: 149:External IDs 72: 4114:Active site 4001:(EC 2.7.12) 3388:Polo kinase 3328:Polo kinase 2137:PDB gallery 1210:cholesterol 722:nucleoplasm 676:ATP binding 656:AMP binding 646:ADP binding 521:granulocyte 388:98,729,402 375:98,710,678 287:49,018,807 274:49,002,274 127:Identifiers 4450:Categories 4317:Isomerases 4291:Hydrolases 4158:Regulation 2679:IκB kinase 2254:2.7.11-12) 1289:, May 2017 1268:, May 2017 1244:References 1206:fatty acid 1200:(ACC) and 433:(ortholog) 170:HomoloGene 4461:EC 2.7.11 4401:on human 4196:EC number 2805:PKC alpha 1091:NP_058061 1070:NP_002724 1036:NM_016781 1015:NM_212461 1011:NM_002733 833:Orthologs 178:GeneCards 4220:Kinetics 4144:Cofactor 4107:Activity 3161:KIAA0999 3056:MAPKAPK5 3051:MAPKAPK3 3046:MAPKAPK2 2078:15058305 2040:85248755 2032:11445078 1997:10698692 1958:19529677 1871:Genomics 1826:39329574 1523:39230415 1469:10698692 1285:– 1264:– 1230:interact 1218:isoforms 1184:Function 1139:Wikidata 812:Sources: 702:membrane 553:gastrula 266:12q13.12 4376:Biology 4330:Ligases 4100:Enzymes 3820:MAP3K14 3798:MAP3K11 3793:MAP3K10 3783:MAP3K13 3778:MAP3K12 3580:RPS6KC1 3575:RPS6KA1 3570:RPS6KA3 3565:RPS6KA2 3560:RPS6KB2 3545:RPS6KA4 3540:RPS6KA5 3191:Kalirin 3156:SNF1LK2 2395:EIF2AK4 2390:EIF2AK3 2244:Kinases 2101:PDBe-KB 2086:4302317 2058:Bibcode 1988:1220898 1950:9730685 1921:9671211 1891:9598317 1861:9278385 1818:9224708 1788:9151826 1745:8889548 1710:8663446 1675:8626596 1640:7946090 1611:7688126 1579:Bibcode 1558:2342480 1515:1978848 1460:1220898 1404:8621499 1363:8557660 1287:Ensembl 1266:Ensembl 945:UniProt 900:Ensembl 839:Species 818:QuickGO 717:nucleus 697:cytosol 517:saccule 408:pattern 134:Aliases 4362:Portal 4304:Lyases 4050:MAP2K7 4045:MAP2K6 4040:MAP2K5 4035:MAP2K4 4030:MAP2K3 4025:MAP2K2 4020:MAP2K1 3971:ACVRL1 3966:ACVR2B 3961:ACVR2A 3956:ACVR1C 3951:ACVR1B 3934:BMPR1B 3929:BMPR1A 3803:MAP3K7 3788:MAP3K9 3739:MAP3K8 3734:MAP3K7 3729:MAP3K6 3724:MAP3K5 3719:MAP3K4 3714:MAP3K3 3709:MAP3K2 3704:MAP3K1 3678:MAPK14 3673:MAPK13 3668:MAPK11 3656:MAPK10 3634:MAPK15 3629:MAPK12 3521:CDC2L1 3496:CDC2L5 3171:SNF1LK 2996:CAMK2G 2991:CAMK2D 2986:CAMK2B 2981:CAMK2A 2971:CAMK1G 2966:CAMK1D 2961:CAMK1B 2956:CAMK1A 2810:PRKCB1 2747:PRKACA 2742:PRKACB 2737:PRKACG 2713:IKBKAP 2539:BCKDHB 2534:BCKDHA 2508:PRKAG3 2503:PRKAG2 2498:PRKAG1 2488:PRKAB2 2483:PRKAB1 2473:PRKAA2 2468:PRKAA1 2313:STK38L 2084:  2076:  2050:Nature 2038:  2030:  1995:  1985:  1956:  1948:  1919:  1889:  1859:  1824:  1816:  1786:  1779:191654 1776:  1743:  1708:  1673:  1638:  1609:  1599:  1556:  1521:  1513:  1467:  1457:  1402:  1361:  1238:PRKAB1 1234:PRKAB2 1175:PRKAG1 1171:enzyme 1169:is an 1125:search 1123:PubMed 978:O54950 959:P54619 855:Entrez 579:BioGPS 182:PRKAG1 166:108411 158:602742 141:PRKAG1 22:PRKAG1 4405:is a 4256:Types 4012:MAP2K 3946:ACVR1 3939:BMPR2 3924:BMPR1 3849:GSK-3 3690:MAP3K 3651:MAPK9 3646:MAPK8 3624:MAPK7 3619:MAPK6 3614:MAPK4 3609:MAPK3 3604:MAPK1 3516:PFTK1 3511:PCTK3 3506:PCTK2 3501:PCTK1 3491:CDK12 3486:CDK10 3461:CDKL5 3441:CDKL2 3318:STK19 3313:EEF2K 3294:PHKG2 3289:PHKG1 3279:PHKA2 3274:PHKA1 3255:MYLK4 3250:MYLK3 3245:MYLK2 3221:DCLK1 3216:Titin 3206:TRIB3 3201:TRIB2 3196:TRIB1 3186:TSSK2 3166:STK40 3151:PSKH1 3146:PRKD3 3141:PRKD2 3121:PHKG2 3116:PHKG1 3106:OBSCN 3101:NUAK2 3096:NUAK1 3091:MKNK2 3086:MKNK1 3076:MARK4 3071:MARK3 3066:MARK2 3061:MARK1 3041:STK11 3036:DAPK3 3031:DAPK2 3026:DAPK1 3021:CHEK2 3016:CHEK1 3001:CAMK4 2976:CAMK2 2951:CAMK1 2946:BRSK2 2840:PRKCQ 2835:PRKCI 2830:PRKCG 2825:PRKCH 2820:PRKCE 2815:PRKCD 2776:PRKG1 2708:IKBKG 2703:IKBKE 2652:STK10 2647:FASTK 2573:IDH3G 2568:IDH3B 2563:IDH3A 2529:BCKDK 2323:ROCK1 2308:STK38 2303:MAST2 2298:MAST1 2293:LATS2 2288:LATS1 2082:S2CID 2036:S2CID 1954:S2CID 1822:S2CID 1602:46995 1519:S2CID 1232:with 888:19082 848:Mouse 843:Human 814:Amigo 541:molar 431:Mouse 424:Human 371:Start 306:Mouse 270:Start 203:Human 174:99712 4407:stub 4399:gene 4348:list 4341:EC7 4335:list 4328:EC6 4322:list 4315:EC5 4309:list 4302:EC4 4296:list 4289:EC3 4283:list 4276:EC2 4270:list 4263:EC1 3839:TPK1 3815:CDC7 3773:MLKs 3766:KSR2 3761:KSR1 3756:BRAF 3751:ARAF 3746:RAFs 3481:CDK9 3476:CDK8 3471:CDK7 3466:CDK6 3456:CDK5 3451:CDK4 3446:CDK3 3436:CDK2 3431:CDK1 3412:PLK4 3407:PLK3 3402:PLK2 3397:PLK1 3352:PLK4 3347:PLK3 3342:PLK2 3337:PLK1 3284:PHKB 3240:MYLK 3211:TRIO 3181:SPEG 3176:SNRK 3136:PKD1 3131:PIM2 3126:PIM1 3111:PASK 3081:MELK 3011:CASK 3006:MLCK 2927:GRK6 2922:GRK5 2917:GRK4 2855:PKN3 2850:PKN2 2752:PRKY 2698:TBK1 2693:IKK2 2688:CHUK 2592:STK4 2558:IDH2 2443:PDK4 2438:PDK3 2433:PDK2 2428:PDK1 2407:WEE1 2402:Wee1 2370:mTOR 2358:AKT3 2353:AKT2 2348:AKT1 2338:SGK3 2333:SGK2 2200:2uv7 2185:2uv6 2170:2uv5 2155:2uv4 2074:PMID 2028:PMID 1993:PMID 1946:PMID 1917:PMID 1887:PMID 1857:PMID 1814:PMID 1784:PMID 1741:PMID 1706:PMID 1671:PMID 1636:PMID 1620:AIDS 1607:PMID 1554:PMID 1511:PMID 1465:PMID 1400:PMID 1359:PMID 1236:and 1208:and 1178:gene 869:5571 414:Bgee 362:Band 323:Chr. 261:Band 220:Chr. 154:OMIM 111:4ZHX 107:5EZV 103:4REW 99:4RER 95:4CFF 91:4CFE 87:2UV7 83:2UV6 79:2UV5 75:2UV4 56:RCSB 53:PDBe 3844:TTK 3808:ZAK 2385:HRI 2380:PKR 2328:SGK 2318:CIT 2066:doi 2054:428 2018:doi 2014:500 1983:PMC 1975:doi 1938:doi 1909:doi 1879:doi 1847:doi 1843:272 1806:doi 1802:409 1774:PMC 1766:doi 1731:doi 1696:doi 1692:271 1661:doi 1657:271 1628:doi 1597:PMC 1587:doi 1544:doi 1501:doi 1497:145 1455:PMC 1447:doi 1390:doi 1386:271 1349:doi 1345:271 384:End 283:End 186:OMA 162:MGI 46:PDB 4452:: 2494:γ 2479:β 2464:α 2252:EC 2246:: 2080:. 2072:. 2064:. 2052:. 2034:. 2026:. 2012:. 2008:. 1991:. 1981:. 1969:. 1952:. 1944:. 1932:. 1915:. 1905:14 1903:. 1885:. 1875:49 1873:. 1855:. 1841:. 1837:. 1820:. 1812:. 1800:. 1782:. 1772:. 1762:71 1760:. 1756:. 1739:. 1725:. 1721:. 1704:. 1690:. 1686:. 1669:. 1655:. 1651:. 1634:. 1622:. 1605:. 1595:. 1585:. 1575:90 1573:. 1569:. 1552:. 1538:. 1534:. 1517:. 1509:. 1495:. 1491:. 1463:. 1453:. 1441:. 1429:^ 1412:^ 1398:. 1384:. 1380:. 1357:. 1343:. 1339:. 1320:. 1302:. 1273:^ 1252:^ 1240:. 1180:. 816:/ 390:bp 377:bp 289:bp 276:bp 184:; 180:: 176:; 172:: 168:; 164:: 160:; 156:: 109:, 105:, 101:, 97:, 93:, 89:, 85:, 81:, 77:, 4438:e 4431:t 4424:v 4413:. 4364:: 4350:) 4346:( 4337:) 4333:( 4324:) 4320:( 4311:) 4307:( 4298:) 4294:( 4285:) 4281:( 4272:) 4268:( 4092:e 4085:t 4078:v 3901:- 3884:- 3867:- 2670:- 2250:( 2236:e 2229:t 2222:v 2130:e 2123:t 2116:v 2088:. 2068:: 2060:: 2042:. 2020:: 1999:. 1977:: 1960:. 1940:: 1934:5 1923:. 1911:: 1893:. 1881:: 1863:. 1849:: 1828:. 1808:: 1790:. 1768:: 1747:. 1733:: 1727:6 1712:. 1698:: 1677:. 1663:: 1642:. 1630:: 1624:8 1613:. 1589:: 1581:: 1560:. 1546:: 1540:4 1525:. 1503:: 1471:. 1449:: 1423:. 1406:. 1392:: 1365:. 1351:: 1324:. 1306:. 308:) 205:) 188::

Index


PDB
PDBe
RCSB
2UV4
2UV5
2UV6
2UV7
4CFE
4CFF
4RER
4REW
5EZV
4ZHX
Aliases
PRKAG1
OMIM
602742
MGI
108411
HomoloGene
99712
GeneCards
PRKAG1
OMA
PRKAG1 - orthologs
Human
Chromosome 12 (human)
Chr.
Chromosome 12 (human)

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.