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726:, usually 90 mg monthly. 30 mg, 60 mg, 90 mg and for hospitals, 120 mg vials are available, mixed with
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is a rare complication which has been associated with the use of bisphosphonates, including pamidronate.
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InChI=1S/C3H11NO7P2/c4-2-1-3(5,12(6,7)8)13(9,10)11/h5H,1-2,4H2,(H2,6,7,8)(H2,9,10,11)
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1002:(Seventh ed.). New Delhi: Jaypee Brothers Medical Publishers Pvt. Limited.
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910:"Treatment of reflex sympathetic dystrophy with pamidronate: 29 cases"
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707:. It is also used as an experimental treatment of the bone disorder
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Kubalek I, Fain O, Paries J, Kettaneh A, Thomas M (December 2001).
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951:"Osteonecrosis of the jaw associated with pamidronate therapy"
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Zarychanski R, Elphee E, Walton P, Johnston J (January 2006).
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It was patented in 1971 and approved for medical use in 1987.
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278:(3-amino-1-hydroxypropane-1,1-diyl)bis(phosphonic acid)
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Pamidronate disodium pentahydrate, pamidronate disodium
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887:. John Wiley & Sons. p. 523.
695:with high propensity to bone, such as
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1256:Parathyroid hormone-related protein
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1321:. You can help Knowledge (XXG) by
1000:Essentials of medical pharmacology
703:in bone, it is also used to treat
699:. Due to its ability to sequester
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14:
1383:Musculoskeletal system drug stubs
1301:
525:
519:
927:10.1093/rheumatology/40.12.1394
881:Fischer J, Ganellin CR (2006).
615:Key:WRUUGTRCQOWXEG-UHFFFAOYSA-N
955:American Journal of Hematology
713:complex regional pain syndrome
687:, to prevent bone loss due to
528:
513:
1:
884:Analogue-based Drug Discovery
46:Aredia, Pamimed, among others
757:Pamidronate activates human
1153:Bone morphogenetic proteins
590:O=P(O)(O)C(O)(CCN)P(=O)(O)O
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998:Tripathi KD (2013-09-30).
503:Chemical and physical data
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1313:article relating to the
752:Osteonecrosis of the jaw
70:International Drug Names
1194:Aluminium chlorohydrate
1058:Drugs for treatment of
709:osteogenesis imperfecta
1315:musculoskeletal system
1199:Dual action bone agent
675:It is used to prevent
776:upon administration.
1182:Resorption inhibitor
772:, which may lead to
691:use, and in certain
652:among others), is a
642:pamidronate disodium
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705:high calcium levels
179:(Prescription only)
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1204:Strontium ranelate
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740:low calcium levels
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920:(12): 1394–1397.
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793:Relative potency
785:Relative potency
774:flu-like symptoms
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780:Pharmacology
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662:osteoporosis
656:-containing
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245:28 ± 7 hours
238:Elimination
162:Legal status
156:Legal status
1242:Cathepsin K
1234:Romosozumab
1187:Ipriflavone
1081:Nitrogenous
857:Zoledronate
847:Risedronate
837:Ibandronate
827:Alendronate
809:Tiludronate
724:Intravenous
552: g·mol
492:100.049.897
262:Identifiers
125:Intravenous
78:MedlinePlus
51:Other names
42:Trade names
1362:Categories
1276:Calcitonin
1249:Odanacatib
1227:Sclerostin
868:References
799:Etidronate
759:γδ T cells
557:3D model (
545:Molar mass
402:OYY3447OMC
373:ChemSpider
333:IUPHAR/BPS
297:40391-99-9
288:CAS Number
271:IUPAC name
228:Metabolism
1286:Vitamin D
1259:analogues
1244:inhibitor
1229:inhibitor
1219:Denosumab
1214:inhibitor
1018:868299888
841:500-1000
748:dizziness
442:ChEMBL834
251:Excretion
240:half-life
118:Routes of
92:Pregnancy
64:Drugs.com
985:11830192
977:16369966
936:11752511
831:100-500
763:in vitro
728:mannitol
654:nitrogen
628:(verify)
353:DrugBank
132:ATC code
107: B3
94:category
1281:Calcium
769:in vivo
701:calcium
693:cancers
689:steroid
550:235.069
509:Formula
362:DB00282
308:PubChem
148:)
142: (
140:M05BA03
84:a601163
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744:nausea
650:Aredia
583:SMILES
433:ChEMBL
422:D07281
190:℞-only
188:
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1317:is a
1309:This
1212:RANKL
1175:Other
981:S2CID
861:5000
851:1000
603:InChI
559:JSmol
256:Renal
1319:stub
1311:drug
1014:OCLC
1004:ISBN
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889:ISBN
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766:and
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413:KEGG
393:UNII
382:4512
342:7259
322:4674
202:data
60:AHFS
1064:M05
963:doi
922:doi
813:10
646:APD
644:or
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458:EPA
312:CID
232:Nil
222:54%
212:n/a
177:POM
145:WHO
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62:/
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