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Perilymph is the fluid contained within the bony labyrinth, surrounding and protecting the membranous labyrinth; perilymph resembles extracellular fluid in composition (sodium salts are the predominant positive electrolyte) and, via the cochlear aqueduct (sometimes referred to as the "perilymphatic
291:
Apart from the importance in the electric cochlear potential, the perilymph also contains a large number of proteins, e.g. extracellular enzymes and immunoglobulins. These proteins are important for the immune response and metabolism among others physiological functions.
321:
Bosher SK, Warren RL (1968-11-05). "Observations on the electrochemistry of the cochlear endolymph of the rat: a quantitative study of its electrical potential and ionic composition as determined by means of flame spectrophotometry".
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269:
of endolymph is ~80-90 mV more positive than perilymph due to a higher concentration of potassium cations (K) in endolymph and higher sodium (Na) in perilymph. This is referred to as the
284:
Endolymph is the fluid contained within the scala media of the membranous labyrinth of the inner ear and within the semicircular canals of the vestibular apparatus; endolymph resembles
599:
126:
592:
102:
221:
has two major parts, the cochlea and the vestibular organ. They are connected in a series of canals in the temporal bone referred to as the
512:"The proteome of perilymph in patients with vestibular schwannoma. A possibility to identify biomarkers for tumor associated hearing loss?"
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It has also been suggested that perilymph and endolymph participate in a unidirectional flow that is interrupted in
812:
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416:
Konishi T, Hamrick PE, Walsh PJ (1978). "Ion transport in guinea pig cochlea. I. Potassium and sodium transport".
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Edvardsson
Rasmussen, Jesper; Laurell, Göran; Rask-Andersen, Helge; Bergquist, Jonas; Eriksson, Per Olof (2018).
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233:, and is surrounded by perilymph. The perilymph in the bony labyrinth serves as connection to the
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455:"Supporting sensory transduction: cochlear fluid homeostasis and the endocochlear potential"
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225:. The bone canals are separated by the membranes in parallel spaces referred to as the
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205:, respectively. It is also named Cotunnius' liquid and liquor cotunnii for
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Cross-section of semi-circular canal and duct showing perilymphatic space
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have unique ionic compositions suited to their functions in regulating
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173:. The ionic composition of perilymph is comparable to that of
45:- the aqua regions at the top and bottom of the diagram.
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403:Neuroanatomy through Clinical Cases second edition
16:Extracellular fluid located within the inner ear
288:in composition (potassium is the main cation).
197:concentration in the perilymph being 138
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376:"Membranous Labyrinth - an overview"
229:. The membranous labyrinth contains
325:Proceedings of the Royal Society B
14:
453:Wangemann, Philine (2006-10-01).
1003:Reissner's/vestibular membrane
277:duct"), is in continuity with
37:. Perilymph is located in the
1:
746:promontory of tympanic cavity
537:10.1371/journal.pone.0198442
471:10.1113/jphysiol.2006.112888
736:secondary tympanic membrane
265:necessary for hearing. The
1260:
741:prominence of facial canal
405:. Sinauer Associates, Inc.
459:The Journal of Physiology
432:10.3109/00016487809124717
161:. It is found within the
132:
50:
26:
761:aditus to mastoid antrum
401:Blumenfeld, Hal (2010).
346:10.1098/rspb.1968.0066
271:endocochlear potential
134:Anatomical terminology
752:Posterior structures
296:Clinical significance
189:, with the values of
993:Cochlear duct /
957:Perilymphatic space
857:Auditory tube /
227:membranous labyrinth
1175:Semicircular canals
1148:Vestibular aqueduct
528:2018PLoSO..1398442E
338:1968RSPSB.171..227B
286:intracellular fluid
279:cerebrospinal fluid
235:cerebrospinal fluid
179:cerebrospinal fluid
157:located within the
155:extracellular fluid
1153:endolymphatic duct
1141:Otolithic membrane
1054:Tectorial membrane
1013:Reticular membrane
818:posterior ligament
766:pyramidal eminence
722:Medial structures
267:electric potential
243:perilymphatic duct
239:subarachnoid space
1226:
1225:
1222:
1221:
1218:
1217:
1208:crista ampullaris
1158:endolymphatic sac
1090:Vestibular system
1084:
1083:
966:Cochlear aqueduct
875:
874:
813:superior ligament
801:anterior ligament
791:superior ligament
679:Auricular muscles
662:intertragic notch
332:(1023): 227–247.
302:Ménière's disease
148:
147:
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33:Cross-section of
1251:
1198:Ampullary cupula
1095:
1025:Stria vascularis
1008:Basilar membrane
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830:annular ligament
796:lateral ligament
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419:Acta Otolaryngol
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207:Domenico Cotugno
185:in perilymph is
140:edit on Wikidata
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1165:Ductus reuniens
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1059:Sulcus spiralis
1030:Spiral ligament
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951:Cochlear cupula
931:Vestibular duct
911:Auditory system
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859:Eustachian tube
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715:Tympanic cavity
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522:(6): e0198442.
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575:External links
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426:(1–2): 22–34.
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253:Perilymph and
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223:bony labyrinth
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694:pars flaccida
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163:scala tympani
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43:scala tympani
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1058:
960:
731:round window
519:
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385:. Retrieved
379:
370:
329:
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290:
283:
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261:impulses of
252:
216:
181:. The major
150:
149:
103:A15.3.03.056
78:
1244:Body fluids
1042:stereocilia
995:scala media
936:Helicotrema
726:oval window
615:Anatomy of
249:Composition
68:Identifiers
1233:Categories
1193:Horizontal
1131:Kinocilium
896:membranous
889:Labyrinths
706:Middle ear
657:antitragus
387:2021-03-17
308:References
263:hair cells
79:perilympha
1188:Posterior
1099:Vestibule
1047:tip links
1020:Endolymph
981:Boettcher
961:Perilymph
881:Inner ear
840:stapedius
674:Ear canal
647:antihelix
629:Outer ear
546:1932-6203
479:0022-3751
255:endolymph
231:endolymph
219:inner ear
213:Structure
195:potassium
159:inner ear
151:Perilymph
22:Perilymph
1203:Ampullae
1183:Superior
1069:internus
1064:externus
976:Claudius
946:Modiolus
836:Muscles
778:Ossicles
564:29856847
516:PLOS ONE
497:16857713
362:32638469
241:via the
1136:Otolith
1119:Saccule
1107:Utricle
926:Cochlea
919:General
786:Malleus
684:Eardrum
667:earlobe
637:Auricle
621:balance
617:hearing
555:5983529
524:Bibcode
488:1995626
354:4386844
334:Bibcode
237:of the
171:cochlea
169:of the
91:D010498
63:Details
35:cochlea
1124:macula
1112:macula
972:Cells
825:Stapes
652:tragus
562:
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544:
495:
485:
477:
440:696294
438:
360:
352:
191:sodium
187:sodium
183:cation
175:plasma
153:is an
808:Incus
642:helix
358:S2CID
138:[
127:60908
74:Latin
901:bony
689:umbo
619:and
560:PMID
542:ISSN
493:PMID
475:ISSN
436:PMID
350:PMID
217:The
193:and
177:and
165:and
115:6938
98:TA98
86:MeSH
41:and
1239:Ear
550:PMC
532:doi
483:PMC
467:doi
463:576
428:doi
342:doi
330:171
122:FMA
110:TA2
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245:.
209:.
203:mM
199:mM
608:e
601:t
594:v
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430::
390:.
364:.
344::
336::
142:]
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
