Knowledge (XXG)

Peter J. H. Scott

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and radiocyanation of (mesityl)(aryl)iodonium salts, boronic acids and stannanes, as well as new methods for radiofluorination of C-H bonds and aryl halides. Scott has also introduced methods for green radiochemistry, for which he received the Michigan
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Wright, Jay S.; Kaur, Tanpreet; Preshlock, Sean; Tanzey, Sean S.; Winton, Wade P.; Sharninghausen, Liam S.; Wiesner, Nicholas; Brooks, Allen F.; Sanford, Melanie S.; Scott, Peter J. H. (May 26, 2020).
166:(born July 27, 1979) is a British and American chemist and radiochemist who is a professor of radiology, professor of pharmacology and professor of medicinal chemistry, as well as a core member of the 251: 1184: 964:
Stewart, Megan N.; Hockley, Brian G.; Scott, Peter J. H. (2015). "Green approaches to late-stage fluorination: radiosyntheses of 18F-labelled radiopharmaceuticals in ethanol and water".
272: 271:), and received a Distinguished Investigator Award from the Academy for Radiology & Biomedical Imaging Research. In 2021, he was honored as a Fellow of the 562:
Mossine, Andrew V.; Brooks, Allen F.; Makaravage, Katarina J.; Miller, Jason M.; Ichiishi, Naoko; Sanford, Melanie S.; Scott, Peter J. H. (December 4, 2015).
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4. Radiochemical Syntheses: Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production, Volume 2 (Editor, 2015)
1204: 1189: 167: 1151: 268: 214:, under the mentorship of Patrick G. Steel. Scott then moved to the United States to undertake postdoctoral research in organometallic chemistry at 160: 1194: 1179: 850:
Lee, So Jeong; Brooks, Allen F.; Ichiishi, Naoko; Makaravage, Katarina J.; Mossine, Andrew V.; Sanford, Melanie S.; Scott, Peter J. H. (2019).
1035:"The Academy for Radiology & Biomedical Imaging Research Announces the Recipients of its Eighth Annual Distinguished Investigator Award" 1126:
Radiochemical Syntheses: Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production, Volume 2;
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2. Solid-Phase Organic Syntheses, Volume 2: Solid-Phase Palladium Chemistry (Wiley Series on Solid-Phase Organic Syntheses) (Editor, 2012)
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Ichiishi, Naoko; Brooks, Allen F.; Topczewski, Joseph J.; Rodnick, Melissa E.; Sanford, Melanie S.; Scott, Peter J. H. (June 20, 2014).
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McCammant, Matthew S.; Thompson, Stephen; Brooks, Allen F.; Krska, Shane W.; Scott, Peter J. H.; Sanford, Melanie S. (July 21, 2017).
298: 275:, and was also recognized by SNMMI in 2023 with the Sam Gambhir Trailblazer Award, created to honor the legacy and memory of the late 907:
Sharninghausen, Liam S.; Brooks, Allen F.; Winton, Wade P.; Makaravage, Katarina J.; Scott, Peter J. H.; Sanford, Melanie S. (2020).
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Makaravage, Katarina J.; Shao, Xia; Brooks, Allen F.; Yang, Lingyun; Sanford, Melanie S.; Scott, Peter J. H. (February 27, 2018).
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in the United States. He is Chief of Nuclear Medicine and director of the University of Michigan Positron Emission Tomography (
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Makaravage, Katarina J.; Brooks, Allen F.; Mossine, Andrew V.; Sanford, Melanie S.; Scott, Peter J. H. (October 10, 2016).
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Solid-Phase Organic Syntheses, Volume 2: Solid-Phase Palladium Chemistry (Wiley Series on Solid-Phase Organic Syntheses);
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Lee, So Jeong; Makaravage, Katarina J.; Brooks, Allen F.; Scott, Peter J. H.; Sanford, Melanie S. (January 18, 2019).
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https://www.iaea.org/publications/14925/production-and-quality-control-of-fluorine-18-labelled-radiopharmaceuticals
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in 2001, after conducting research with Raymond Jones. He subsequently obtained his PhD in organic chemistry from
246:. His methodology work aims to improve the synthesis of PET radiotracers and he has an active collaboration with 1199: 450:"Copper-mediated late-stage radiofluorination: five years of impact on preclinical and clinical PET imaging" 203: 195: 59: 1174: 1073: 291:
3. Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1 (Editor, 2012)
171: 111: 215: 1169: 564:"Synthesis of [18F]Arenes via the Copper-Mediated [18F]Fluorination of Boronic Acids" 219: 145: 1139: 1127: 1115: 1103: 1091: 1055: 297:
6. Production and Quality Control of Fluorine-18 Labelled Radiopharmaceuticals (co-authored with
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Academy for Radiology & Biomedical Imaging Research: 2019 Distinguished Investigator Award;
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5. Handbook of Radiopharmaceuticals (2nd Edition): Methodology and Applications (Editor, 2021)
255: 243: 207: 163: 62: 973: 936: 920: 879: 863: 822: 806: 765: 749: 708: 692: 651: 635: 591: 575: 534: 518: 477: 461: 132: 101: 795:"Copper-Mediated Aminoquinoline-Directed Radiofluorination of Aromatic Cāˆ’H Bonds with K18F" 1114:
Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1;
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Society of Nuclear Medicine and Molecular Imaging: 2023 Sam Gambhir Trailblazer Award.
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Scott runs a research group developing new metal-catalyzed methods for incorporating
624:"Copper(II)-Mediated [11C]Cyanation of Arylboronic Acids and Arylstannanes" 434: 396: 753: 696: 639: 579: 231: 32: 507:"Copper-Catalyzed [ 18 F]Fluorination of (Mesityl)(aryl)iodonium Salts" 465: 263:
Governor's Award in 2014. In 2019, Prof. Scott was elected as a Fellow of the
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Production and Quality Control of Fluorine-18 Labelled Radiopharmaceuticals;
985: 932: 875: 818: 761: 704: 647: 587: 530: 473: 319: 89: 993: 950: 893: 836: 810: 779: 722: 665: 605: 548: 491: 924: 681:"Copper-Mediated Radiofluorination of Arylstannanes with [18F]KF" 977: 909:"NHC-Copper Mediated Ligand-Directed Radiofluorination of Aryl Halides" 867: 1074:"Peter J. H. Scott, PhD, Receives SNMMI Sam Gambhir Trailblazer Award" 522: 435:"Copper-mediated Late-Stage Radiofluorination of Electron-rich Arenes" 125:
Perfluoroalkanesulfonyl linker units for solid phase organic synthesis
371:"PET Center | Radiology | Michigan Medicine | University of Michigan" 345: 118: 287:
1. Linker Strategies in Solid-phase Organic Synthesis (Editor, 2009)
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Peter Scott was born and grew up in North East England and attended
852:"Cā€“H 18F-fluorination of 8-methylquinolines with Ag[18F]F" 738:"Cu-Mediated Cā€“H 18F-Fluorination of Electron-Rich (Hetero)arenes" 124: 1140:
https://onlinelibrary.wiley.com/doi/book/10.1002/9781119500575
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https://onlinelibrary.wiley.com/doi/book/10.1002/9781118834114
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https://onlinelibrary.wiley.com/doi/book/10.1002/9781118140345
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https://onlinelibrary.wiley.com/doi/book/10.1002/9781118336953
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https://onlinelibrary.wiley.com/doi/book/10.1002/9780470749043
254:. Together they have developed methods for the Cu-mediated 416:"UM scientists improve synthesis of PET imaging molecules" 1024:
Fellows. The Times, March 12, 2019, p. 55, col. E&F.
320:"Radiology | Michigan Medicine | University of Michigan" 1090:
Linker Strategies in Solid-phase Organic Synthesis;
1008:"Michigan Green Chemistry Governor's Awards Program" 178:) Center, and runs a research group developing new 141: 131: 117: 107: 85: 68: 55: 47: 39: 23: 1185:British expatriate academics in the United States 273:Society of Nuclear Medicine and Molecular Imaging 202:in medicinal and pharmaceutical chemistry from 346:"Medicinal Chemistry | UM College of Pharmacy" 238:into bioactive molecules as well as novel PET 8: 198:. He received his undergraduate degree with 31: 20: 940: 883: 826: 769: 712: 655: 595: 538: 481: 913:Journal of the American Chemical Society 799:Angewandte Chemie International Edition 311: 617: 615: 7: 1138:Handbook of Radiopharmaceuticals; 454:Clinical and Translational Imaging 299:International Atomic Energy Agency 210:in 2005, where he was a member of 14: 1205:Alumni of Ustinov College, Durham 1190:Alumni of Loughborough University 414:Haynes, Sarah (October 3, 2018). 433:Scott, Peter; Sanford, Melanie. 1195:University of Michigan faculty 1: 1180:21st-century British chemists 142:Other academic advisors 98:Positron emission tomography 754:10.1021/acs.orglett.7b01902 697:10.1021/acs.orglett.6b02911 640:10.1021/acs.orglett.8b00242 580:10.1021/acs.orglett.5b02875 244:neurodegenerative disorders 1221: 466:10.1007/s40336-020-00368-y 265:Royal Society of Chemistry 182:methodology and novel PET 151: 78: 30: 397:"Peter J. Scott profile" 250:group that is funded by 966:Chemical Communications 856:Chemical Communications 248:Prof. Melanie Sanford's 204:Loughborough University 196:Whitley Bay High School 60:Loughborough University 811:10.1002/anie.201812701 172:University of Michigan 112:University of Michigan 18:American radiochemist 925:10.1021/jacs.0c02637 401:mcommunity.umich.edu 146:Huw Davies (chemist) 51:British and American 972:(79): 14805ā€“14808. 168:Rogel Cancer Center 978:10.1039/c5cc05919d 868:10.1039/c9cc00641a 377:. January 30, 2014 375:medicine.umich.edu 350:pharmacy.umich.edu 324:medicine.umich.edu 277:Sanjiv Sam Gambhir 200:first class honors 919:(16): 7362ā€“7367. 862:(20): 2976ā€“2979. 805:(10): 3119ā€“3122. 748:(14): 3939ā€“3942. 691:(20): 5440ā€“5443. 574:(23): 5780ā€“5783. 523:10.1021/ol501243g 517:(12): 3224ā€“3227. 326:. January 6, 2014 256:radiofluorination 208:Durham University 158:Peter J. H. Scott 155: 154: 80:Scientific career 63:Durham University 1212: 1154: 1148: 1142: 1136: 1130: 1124: 1118: 1112: 1106: 1100: 1094: 1088: 1082: 1081: 1070: 1064: 1063: 1052: 1046: 1045: 1039: 1031: 1025: 1022: 1016: 1015: 1004: 998: 997: 961: 955: 954: 944: 904: 898: 897: 887: 847: 841: 840: 830: 790: 784: 783: 773: 733: 727: 726: 716: 676: 670: 669: 659: 634:(6): 1530ā€“1533. 619: 610: 609: 599: 559: 553: 552: 542: 502: 496: 495: 485: 445: 439: 438: 430: 424: 423: 411: 405: 404: 393: 387: 386: 384: 382: 367: 361: 360: 358: 356: 342: 336: 335: 333: 331: 316: 137:Patrick G. Steel 133:Doctoral advisor 102:Nuclear Medicine 35: 21: 1220: 1219: 1215: 1214: 1213: 1211: 1210: 1209: 1160: 1159: 1158: 1157: 1149: 1145: 1137: 1133: 1125: 1121: 1113: 1109: 1101: 1097: 1089: 1085: 1072: 1071: 1067: 1056:"SNMMI Fellows" 1054: 1053: 1049: 1037: 1033: 1032: 1028: 1023: 1019: 1006: 1005: 1001: 963: 962: 958: 906: 905: 901: 849: 848: 844: 792: 791: 787: 742:Organic Letters 735: 734: 730: 685:Organic Letters 678: 677: 673: 628:Organic Letters 621: 620: 613: 568:Organic Letters 561: 560: 556: 511:Organic Letters 504: 503: 499: 447: 446: 442: 432: 431: 427: 413: 412: 408: 395: 394: 390: 380: 378: 369: 368: 364: 354: 352: 344: 343: 339: 329: 327: 318: 317: 313: 308: 302: 296: 294: 292: 290: 288: 285: 261:Green Chemistry 228: 212:Ustinov College 192: 100: 96: 92: 73: 26: 19: 12: 11: 5: 1218: 1216: 1208: 1207: 1202: 1200:Radiochemistry 1197: 1192: 1187: 1182: 1177: 1172: 1162: 1161: 1156: 1155: 1143: 1131: 1119: 1107: 1095: 1083: 1065: 1047: 1026: 1017: 999: 956: 899: 842: 785: 728: 671: 611: 554: 497: 460:(3): 167ā€“206. 440: 425: 406: 388: 362: 337: 310: 309: 307: 304: 284: 281: 227: 224: 191: 188: 180:radiochemistry 153: 152: 149: 148: 143: 139: 138: 135: 129: 128: 121: 115: 114: 109: 105: 104: 94:Radiochemistry 87: 83: 82: 76: 75: 70: 66: 65: 57: 53: 52: 49: 45: 44: 41: 37: 36: 28: 27: 24: 17: 13: 10: 9: 6: 4: 3: 2: 1217: 1206: 1203: 1201: 1198: 1196: 1193: 1191: 1188: 1186: 1183: 1181: 1178: 1176: 1175:Living people 1173: 1171: 1168: 1167: 1165: 1153: 1147: 1144: 1141: 1135: 1132: 1129: 1123: 1120: 1117: 1111: 1108: 1105: 1099: 1096: 1093: 1087: 1084: 1079: 1075: 1069: 1066: 1061: 1057: 1051: 1048: 1043: 1036: 1030: 1027: 1021: 1018: 1013: 1009: 1003: 1000: 995: 991: 987: 983: 979: 975: 971: 967: 960: 957: 952: 948: 943: 938: 934: 930: 926: 922: 918: 914: 910: 903: 900: 895: 891: 886: 881: 877: 873: 869: 865: 861: 857: 853: 846: 843: 838: 834: 829: 824: 820: 816: 812: 808: 804: 800: 796: 789: 786: 781: 777: 772: 767: 763: 759: 755: 751: 747: 743: 739: 732: 729: 724: 720: 715: 710: 706: 702: 698: 694: 690: 686: 682: 675: 672: 667: 663: 658: 653: 649: 645: 641: 637: 633: 629: 625: 618: 616: 612: 607: 603: 598: 593: 589: 585: 581: 577: 573: 569: 565: 558: 555: 550: 546: 541: 536: 532: 528: 524: 520: 516: 512: 508: 501: 498: 493: 489: 484: 479: 475: 471: 467: 463: 459: 455: 451: 444: 441: 436: 429: 426: 421: 420:lsa.umich.edu 417: 410: 407: 402: 398: 392: 389: 376: 372: 366: 363: 351: 347: 341: 338: 325: 321: 315: 312: 305: 303: 300: 282: 280: 278: 274: 270: 266: 262: 257: 253: 249: 245: 241: 237: 233: 225: 223: 221: 217: 213: 209: 205: 201: 197: 189: 187: 185: 181: 177: 173: 169: 165: 162: 159: 150: 147: 144: 140: 136: 134: 130: 127: 126: 122: 120: 116: 113: 110: 106: 103: 99: 95: 91: 88: 84: 81: 77: 71: 67: 64: 61: 58: 54: 50: 46: 43:July 27, 1979 42: 38: 34: 29: 22: 16: 1146: 1134: 1122: 1110: 1098: 1086: 1077: 1068: 1059: 1050: 1041: 1029: 1020: 1012:michigan.gov 1011: 1002: 969: 965: 959: 916: 912: 902: 859: 855: 845: 802: 798: 788: 745: 741: 731: 688: 684: 674: 631: 627: 571: 567: 557: 514: 510: 500: 457: 453: 443: 428: 419: 409: 400: 391: 379:. Retrieved 374: 365: 353:. Retrieved 349: 340: 328:. Retrieved 323: 314: 286: 283:Bibliography 242:for imaging 240:radiotracers 229: 216:SUNY Buffalo 193: 184:radiotracers 157: 156: 123: 108:Institutions 79: 15: 1170:1979 births 1042:acadrad.org 232:fluorine-18 48:Citizenship 25:Peter Scott 1164:Categories 306:References 220:Huw Davies 1078:snmmi.org 1060:snmmi.org 986:1359-7345 933:0002-7863 876:1359-7345 819:1433-7851 762:1523-7060 705:1523-7060 648:1523-7060 588:1523-7060 531:1523-7060 474:2281-5872 236:carbon-11 90:Chemistry 56:Education 994:26300287 951:32250612 894:30778496 837:30605563 780:28665619 723:27718581 666:29484880 606:26568457 549:24890658 492:33748018 301:, 2021) 226:Research 942:7314054 885:6556205 828:6476334 771:5525103 714:5078836 657:5892454 597:4672358 540:4076000 483:7968072 170:at the 992:  984:  949:  939:  931:  892:  882:  874:  835:  825:  817:  778:  768:  760:  721:  711:  703:  664:  654:  646:  604:  594:  586:  547:  537:  529:  490:  480:  472:  381:May 1, 355:May 1, 330:May 1, 218:under 119:Thesis 86:Fields 69:Awards 1038:(PDF) 252:NIBIB 164:CChem 990:PMID 982:ISSN 947:PMID 929:ISSN 890:PMID 872:ISSN 833:PMID 815:ISSN 776:PMID 758:ISSN 719:PMID 701:ISSN 662:PMID 644:ISSN 602:PMID 584:ISSN 545:PMID 527:ISSN 488:PMID 470:ISSN 383:2019 357:2019 332:2019 269:FRSC 234:and 190:Life 161:FRSC 40:Born 974:doi 937:PMC 921:doi 917:142 880:PMC 864:doi 823:PMC 807:doi 766:PMC 750:doi 709:PMC 693:doi 652:PMC 636:doi 592:PMC 576:doi 535:PMC 519:doi 478:PMC 462:doi 176:PET 1166:: 1076:. 1058:. 1040:. 1010:. 988:. 980:. 970:51 968:. 945:. 935:. 927:. 915:. 911:. 888:. 878:. 870:. 860:55 858:. 854:. 831:. 821:. 813:. 803:58 801:. 797:. 774:. 764:. 756:. 746:19 744:. 740:. 717:. 707:. 699:. 689:18 687:. 683:. 660:. 650:. 642:. 632:20 630:. 626:. 614:^ 600:. 590:. 582:. 572:17 570:. 566:. 543:. 533:. 525:. 515:16 513:. 509:. 486:. 476:. 468:. 456:. 452:. 418:. 399:. 373:. 348:. 322:. 279:. 186:. 1080:. 1062:. 1044:. 1014:. 996:. 976:: 953:. 923:: 896:. 866:: 839:. 809:: 782:. 752:: 725:. 695:: 668:. 638:: 608:. 578:: 551:. 521:: 494:. 464:: 458:8 437:. 422:. 403:. 385:. 359:. 334:. 267:(

Index


Loughborough University
Durham University
Chemistry
Radiochemistry
Positron emission tomography
Nuclear Medicine
University of Michigan
Thesis
Perfluoroalkanesulfonyl linker units for solid phase organic synthesis
Doctoral advisor
Huw Davies (chemist)
FRSC
CChem
Rogel Cancer Center
University of Michigan
PET
radiochemistry
radiotracers
Whitley Bay High School
first class honors
Loughborough University
Durham University
Ustinov College
SUNY Buffalo
Huw Davies
fluorine-18
carbon-11
radiotracers
neurodegenerative disorders

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