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467:(meperidine). It is not known to have any analgesic activity in its own right, however other derivatives of pethidine with a 4-cyano group in place of the carboxylate ethyl ester have been found to be active, so pethidine intermediate A might also show opioid effects. It is scheduled by
474:. It is a Schedule II Narcotic controlled substance in the United States and has an ACSCN of 9232. The 2014 annual manufacturing quota was 6 grammes (as an end product, presumably for research use).
552:
Lomenzo SA, Rhoden JB, Izenwasser S, Wade D, Kopajtic T, Katz JL, Trudell ML (March 2005). "Synthesis and biological evaluation of meperidine analogues at monoamine transporters".
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526:[Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese).
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524:"RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial"
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InChI=1S/C13H16N2/c1-15-9-7-13(11-14,8-10-15)12-5-3-2-4-6-12/h2-6H,7-10H2,1H3
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152:1-methyl-4-phenylpiperidine-4-carbonitrile
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472:Single Convention on Narcotic Drugs
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420:Key:ZLFQTZYFXYOGLS-UHFFFAOYSA-N
611:Drugs not assigned an ATC code
554:Journal of Medicinal Chemistry
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592:Diversion Control Division
317:Chemical and physical data
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530:(published 2023-04-04).
500:Pethidine intermediate C
494:Pethidine intermediate B
443:Pethidine intermediate A
395:CN1CCC(CC1)(C#N)c2ccccc2
127:Narcotic Schedule I
21:Pethidine intermediate A
528:Diário Oficial da União
489:Methadone intermediate
484:Moramide intermediate
452:derivative that is a
621:4-Phenylpiperidines
23:
616:Synthetic opioids
566:10.1021/jm0401614
502:(pethidinic acid)
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374:Interactive image
267:CompTox Dashboard
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75:Legal status
69:Legal status
357: g·mol
306:100.020.771
136:Identifiers
115:Schedule II
605:Categories
538:2023-08-16
507:References
450:piperidine
362:3D model (
350:Molar mass
236:EL4L2474TY
207:ChemSpider
162:CAS Number
145:IUPAC name
465:pethidine
461:analgesic
454:precursor
171:3627-62-1
102:Anlage II
42:Routes of
626:Nitriles
574:15743177
532:Archived
478:See also
433:(verify)
90:Class A1
54:ATC code
456:to the
445:is a 4-
355:200.285
323:Formula
182:PubChem
100::
572:
520:Anvisa
458:opioid
447:phenyl
388:SMILES
256:C22687
125:
113:
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463:drug
408:InChI
364:JSmol
216:56289
196:62513
570:PMID
247:KEGG
227:UNII
61:none
562:doi
272:EPA
186:CID
48:N/A
607::
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568:.
558:48
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469:UN
337:16
331:13
121:UN
109:US
97:DE
84:BR
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343:2
340:N
334:H
328:C
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270:(
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111::
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
