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491:-Phenetidine has high renal toxicity and it is believed to be responsible for the adverse effects that led to the withdrawal of phenacetin and bucetin from pharmaceutical use.
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Kankuri, Esko; Solatunturi, Erkka; Vapaatalo, Heikki (2003). "Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro".
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of phenetidine. It is used as an intermediate in the synthesis of pharmaceutical drugs, dyes, and the sweetener
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481:. It is also used as a chemical intermediate in the manufacture of bucetin, phenacetin, ethoxyquin, and
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Except where otherwise noted, data are given for materials in their
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Colorless liquid; turns red to brown on exposure to air
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InChI=1S/C8H11NO/c1-2-10-8-5-3-7(9)4-6-8/h3-6H,2,9H2,1H3
443:) is a chemical compound with the molecular formula C
607:"Ethoxyquin: EFSA safety assessment inconclusive"
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609:. European Food Safety Authority. 2015-11-18.
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554:Institute for Occupational Safety and Health
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495:-Phenetidine is also a possible mutagen.
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408:116 °C (241 °F; 389 K)
381:254 °C (489 °F; 527 K)
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271:Key: IMPPGHMHELILKG-UHFFFAOYSA-N
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371:3 °C (37 °F; 276 K)
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518:(12th ed.). p. 1244.
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67:-Phenetidine; 4-Aminophenetole
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582:10.1016/S0049-3848(03)00416-X
469:of the pharmaceutical drugs
451:NO. It is one of the three
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550:GESTIS Substance Database
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477:and of the preservative
632:Human drug metabolites
51:Preferred IUPAC name
570:Thrombosis Research
388:Solubility in water
343: g·mol
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465:-Phenetidine is a
422:Infobox references
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430:Chemical compound
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292:CCOC1=CC=C(C=C1)N
224:CompTox Dashboard
114:Interactive image
16:(Redirected from
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31:-Phenetidine
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524:-Phenetidine
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437:-Phenetidine
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187:RTECS number
73:Identifiers
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62:Other names
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516:Merck Index
404:Flash point
348:Appearance
301:Properties
132:100.005.324
18:Phenetidine
621:Categories
499:References
483:phenacaine
479:ethoxyquin
475:phenacetin
467:metabolite
361:1.07 g/mL
336:Molar mass
212:9TSL224ZSE
101:3D model (
80:CAS Number
194:SI6465500
153:205-855-5
145:EC Number
627:Anilines
590:14592552
398:Hazards
90:156-43-4
552:of the
548:in the
546:Record
471:bucetin
453:isomers
357:Density
341:137.182
163:PubChem
588:
520:7373.
457:dulcin
285:SMILES
45:Names
260:InChI
103:JSmol
586:PMID
473:and
203:UNII
176:9076
65:para
578:doi
574:110
229:EPA
166:CID
623::
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522:p
493:p
489:p
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447:H
445:8
439:(
435:p
329:O
326:N
320:H
317:8
314:C
231:)
227:(
105:)
29:p
20:)
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